Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.93e-20	114	152	19	GO:0004843
GeneOntologyMolecularFunction	deubiquitinase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.03e-19	124	152	19	GO:0101005
GeneOntologyMolecularFunction	ubiquitin-like protein peptidase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	7.26e-19	137	152	19	GO:0019783
GeneOntologyMolecularFunction	cysteine-type peptidase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	4.59e-16	192	152	19	GO:0008234
GeneOntologyMolecularFunction	peptidase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 NUP98 USP17L5 TMPRSS5 USP17L10 USP17L19 ADAM22 AMZ2 USP17L18 USP17L17 ADAMTS9 AOPEP USP17L6P USP17L3 ADAMTS18 ADAMTS20 USP17L22 USP17L15 USP17L8 USP17L13	6.56e-13	654	152	27	GO:0008233
GeneOntologyMolecularFunction	acyltransferase activity	AMFR ZDHHC11B RNF148 BAAT TRIM34 TRIM6 ZDHHC4 CREBBP UBE4A RNF150 KMT2C FBXO25 RNF141 RNF122 ZDHHC11 GPAT2 TRIM38 MED12	2.57e-05	775	152	18	GO:0016746
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	AMFR ZSWIM8 ZMYND11 ZDHHC11B LMCD1 NUP98 KDM3B CIR1 AMBRA1 ACTN3 TRIM6 SKI CREBBP KMT2C ARID1B CBFA2T2 STON2 ZDHHC11 FBXO45 TRIM38 MED12 PHF13	6.84e-05	1160	152	22	GO:0030674
GeneOntologyMolecularFunction	molecular adaptor activity	AMFR ZSWIM8 ZMYND11 ZDHHC11B LMCD1 NUP98 KDM3B CIR1 AMBRA1 RICTOR ACTN3 TRIM6 SKI CREBBP KMT2C ARID1B CBFA2T2 STON2 ZDHHC11 FBXO45 NLRP4 TRIM38 MED12 PHF13	9.14e-05	1356	152	24	GO:0060090
GeneOntologyMolecularFunction	zinc ion binding	ZSWIM8 ZMYND11 LHX4 ZCCHC10 LMCD1 TRIM34 LHX3 TRIM6 SKI CREBBP L3MBTL1 PRICKLE3 ADAMTS9 AOPEP ZNF330 ADAMTS20 TRIM38	4.55e-04	891	152	17	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	ZSWIM8 ZMYND11 LHX4 ZCCHC10 LMCD1 TRIM34 LHX3 TRIM6 SKI TF CREBBP PPM1B L3MBTL1 PRICKLE3 ADAMTS9 AOPEP ZNF330 ADAMTS20 MUC2 TRIM38	7.07e-04	1189	152	20	GO:0046914
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC11B ZDHHC4 ZDHHC11	9.89e-04	26	152	3	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC11B ZDHHC4 ZDHHC11	9.89e-04	26	152	3	GO:0019707
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	AMFR RNF148 TRIM34 TRIM6 UBE4A RNF150 FBXO25 RNF141 RNF122 TRIM38 MED12	1.02e-03	473	152	11	GO:0004842
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate phosphatase activity	MTMR4 PIP4P1 MTMR3	1.11e-03	27	152	3	GO:0034593
GeneOntologyMolecularFunction	chromatin insulator sequence binding	ZNF692 CTCFL	1.18e-03	7	152	2	GO:0043035
GeneOntologyMolecularFunction	transcription coregulator activity	ZMYND11 LMCD1 NUP98 KDM3B CIR1 SKI CREBBP KMT2C ARID1B CBFA2T2 TRIM38 MED12	1.26e-03	562	152	12	GO:0003712
GeneOntologyMolecularFunction	phosphatidylinositol phosphate phosphatase activity	MTMR4 PIP4P1 MTMR3	1.51e-03	30	152	3	GO:0052866
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC11B ZDHHC4 ZDHHC11	1.51e-03	30	152	3	GO:0016417
GeneOntologyMolecularFunction	nodal binding	CFC1 CFC1B	1.56e-03	8	152	2	GO:0038100
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	AMFR RNF148 TRIM34 TRIM6 UBE4A RNF150 FBXO25 RNF141 RNF122 TRIM38 MED12	1.91e-03	512	152	11	GO:0019787
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	AMFR RNF148 TRIM34 TRIM6 UBE4A RNF150 RNF122 TRIM38 MED12	2.23e-03	372	152	9	GO:0061630
GeneOntologyMolecularFunction	rDNA binding	BNC2 BNC1	2.49e-03	10	152	2	GO:0000182
GeneOntologyMolecularFunction	aminoacyltransferase activity	AMFR RNF148 TRIM34 TRIM6 UBE4A RNF150 FBXO25 RNF141 RNF122 TRIM38 MED12	2.56e-03	532	152	11	GO:0016755
GeneOntologyMolecularFunction	palmitoyltransferase activity	ZDHHC11B ZDHHC4 ZDHHC11	2.78e-03	37	152	3	GO:0016409
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	MTMR4 MTMR3	3.03e-03	11	152	2	GO:0052629
GeneOntologyMolecularFunction	lysozyme activity	LYZL1 LYZL2	3.03e-03	11	152	2	GO:0003796
GeneOntologyBiologicalProcess	protein deubiquitination	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	6.64e-20	125	152	19	GO:0016579
GeneOntologyBiologicalProcess	protein modification by small protein removal	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.06e-18	144	152	19	GO:0070646
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	AMFR USP17L21 ZSWIM8 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 AMBRA1 TRIM34 USP17L10 USP17L19 TRIM6 USP17L18 UBE4A FBXO25 USP17L17 RNF141 USP17L6P USP17L3 FBXO32 USP17L22 RNF122 FBXO45 TRIM38 MED12 USP17L15 USP17L8 USP17L13	1.89e-12	1009	152	32	GO:0070647
GeneOntologyBiologicalProcess	post-translational protein modification	AMFR USP17L21 ZSWIM8 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 AMBRA1 TRIM34 USP17L10 USP17L19 TRIM6 USP17L18 UBE4A FBXO25 USP17L17 RNF141 USP17L6P USP17L3 FBXO32 USP17L22 RNF122 FBXO45 TRIM38 MED12 USP17L15 USP17L8 USP17L13	9.78e-12	1074	152	32	GO:0043687
GeneOntologyBiologicalProcess	medial motor column neuron differentiation	LHX4 LHX3	5.40e-05	2	152	2	GO:0021526
GeneOntologyBiologicalProcess	regulation of defense response to virus	ZDHHC11B USP17L2 TRIM6 PPM1B ZDHHC11 TRIM38	5.43e-05	90	152	6	GO:0050688
GeneOntologyBiologicalProcess	motor neuron axon guidance	PLXNA3 LHX4 LHX3 PLXNA4	1.24e-04	35	152	4	GO:0008045
GeneOntologyCellularComponent	endoplasmic reticulum membrane	AMFR USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 ZDHHC4 USP17L18 USP17L17 TMEM259 USP17L6P USP17L3 TMEM151A USP17L22 ZDHHC11 USP17L15 NOTCH4 USP17L8 USP17L13	2.60e-05	1293	154	24	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	AMFR USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 ZDHHC4 USP17L18 USP17L17 TMEM259 USP17L6P USP17L3 TMEM151A USP17L22 ZDHHC11 USP17L15 NOTCH4 USP17L8 USP17L13	2.80e-05	1299	154	24	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	AMFR USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 ZDHHC4 USP17L18 USP17L17 TMEM259 USP17L6P USP17L3 TMEM151A USP17L22 ZDHHC11 USP17L15 NOTCH4 USP17L8 USP17L13	3.94e-05	1327	154	24	GO:0042175
Domain	HABP4_PAI-RBP1	USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13	1.70e-25	16	149	13	PF04774
Domain	HABP4_PAIRBP1-bd	USP17L21 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L13	1.70e-25	16	149	13	IPR006861
Domain	UCH	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13	6.04e-21	71	149	17	PF00443
Domain	USP_2	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13	6.04e-21	71	149	17	PS00973
Domain	USP_3	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13	7.86e-21	72	149	17	PS50235
Domain	USP_dom	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13	7.86e-21	72	149	17	IPR028889
Domain	Peptidase_C19_UCH	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13	7.86e-21	72	149	17	IPR001394
Domain	USP_CS	USP17L21 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13	7.18e-20	66	149	16	IPR018200
Domain	USP_1	USP17L21 USP17L4 USP17L2 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L8 USP17L13	2.03e-19	70	149	16	PS00972
Domain	-	DPF1 AMFR ZMYND11 RNF148 NSD2 TRIM34 TRIM6 UBE4A RNF150 KMT2C MTMR4 RNF141 MTMR3 RNF122 FGD6 TRIM38 PHF13	1.15e-07	449	149	17	3.30.40.10
Domain	Znf_RING/FYVE/PHD	DPF1 AMFR ZMYND11 RNF148 NSD2 TRIM34 TRIM6 UBE4A RNF150 KMT2C MTMR4 RNF141 MTMR3 RNF122 FGD6 TRIM38 PHF13	1.58e-07	459	149	17	IPR013083
Domain	RING	DPF1 AMFR ZMYND11 RNF148 NSD2 TRIM34 TRIM6 RNF150 KMT2C RNF141 RNF122 TRIM38	6.27e-06	305	149	12	SM00184
Domain	Znf_RING	DPF1 AMFR ZMYND11 RNF148 NSD2 TRIM34 TRIM6 RNF150 KMT2C RNF141 RNF122 TRIM38	1.22e-05	326	149	12	IPR001841
Domain	LIM	LHX4 LMCD1 LHX3 LHX8 PRICKLE3 ABLIM2	1.85e-05	69	149	6	PF00412
Domain	EGF_3	ADAM22 LRP8 CRELD1 MALRD1 CFC1 UMOD CFC1B EGFL8 NOTCH4 OTOG	1.95e-05	235	149	10	PS50026
Domain	-	LHX4 LMCD1 LHX3 LHX8 PRICKLE3 ABLIM2	2.01e-05	70	149	6	2.10.110.10
Domain	LIM	LHX4 LMCD1 LHX3 LHX8 PRICKLE3 ABLIM2	2.18e-05	71	149	6	SM00132
Domain	Znf_LIM	LHX4 LMCD1 LHX3 LHX8 PRICKLE3 ABLIM2	2.18e-05	71	149	6	IPR001781
Domain	LIM_DOMAIN_1	LHX4 LMCD1 LHX3 LHX8 PRICKLE3 ABLIM2	2.18e-05	71	149	6	PS00478
Domain	LIM_DOMAIN_2	LHX4 LMCD1 LHX3 LHX8 PRICKLE3 ABLIM2	2.18e-05	71	149	6	PS50023
Domain	Znf_FYVE_PHD	DPF1 ZMYND11 NSD2 KMT2C MTMR4 MTMR3 FGD6 PHF13	2.38e-05	147	149	8	IPR011011
Domain	EGF-like_dom	ADAM22 LRP8 CRELD1 MALRD1 CFC1 UMOD CFC1B EGFL8 NOTCH4 OTOG	3.20e-05	249	149	10	IPR000742
Domain	Pept_M12B_GON-ADAMTSs	ADAMTS9 ADAMTS20	6.32e-05	2	149	2	IPR012314
Domain	GON	ADAMTS9 ADAMTS20	6.32e-05	2	149	2	PS51046
Domain	GON	ADAMTS9 ADAMTS20	6.32e-05	2	149	2	PF08685
Domain	LYZL1/LYZL2	LYZL1 LYZL2	6.32e-05	2	149	2	IPR030057
Domain	EGF	ADAM22 LRP8 CRELD1 MALRD1 CFC1 UMOD CFC1B EGFL8 NOTCH4	1.15e-04	235	149	9	SM00181
Domain	ZINC_PROTEASE	ADAM22 AMZ2 ADAMTS9 AOPEP ADAMTS18 ADAMTS20	1.34e-04	98	149	6	PS00142
Domain	CFC	CFC1 CFC1B	1.89e-04	3	149	2	PF09443
Domain	Cryptic/Cripto_CFC-dom	CFC1 CFC1B	1.89e-04	3	149	2	IPR019011
Domain	EGF_1	ADAM22 LRP8 CRELD1 MALRD1 CFC1 UMOD CFC1B EGFL8 NOTCH4	2.12e-04	255	149	9	PS00022
Domain	EGF-like_CS	ADAM22 LRP8 CRELD1 MALRD1 CFC1 UMOD CFC1B EGFL8 NOTCH4	2.52e-04	261	149	9	IPR013032
Domain	Pep_M12B_propep	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	2.58e-04	39	149	4	PF01562
Domain	Peptidase_M12B_N	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	2.58e-04	39	149	4	IPR002870
Domain	EGF_2	ADAM22 LRP8 CRELD1 MALRD1 CFC1 UMOD CFC1B EGFL8 NOTCH4	2.82e-04	265	149	9	PS01186
Domain	DISINTEGRIN_1	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	2.84e-04	40	149	4	PS00427
Domain	Reprolysin	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	2.84e-04	40	149	4	PF01421
Domain	ADAM_MEPRO	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	2.84e-04	40	149	4	PS50215
Domain	DISINTEGRIN_2	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	2.84e-04	40	149	4	PS50214
Domain	Peptidase_M12B	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	2.84e-04	40	149	4	IPR001590
Domain	Disintegrin_dom	ADAM22 ADAMTS9 ADAMTS18 ADAMTS20	3.13e-04	41	149	4	IPR001762
Domain	PHD	DPF1 ZMYND11 NSD2 KMT2C PHF13	3.33e-04	75	149	5	PF00628
Domain	Znf_PHD-finger	DPF1 ZMYND11 NSD2 KMT2C PHF13	4.24e-04	79	149	5	IPR019787
Domain	zf-C3HC4	AMFR RNF148 TRIM34 TRIM6 RNF150 RNF141 RNF122 TRIM38	4.29e-04	223	149	8	PF00097
Domain	Znf_C3HC4_RING-type	AMFR RNF148 TRIM34 TRIM6 RNF150 RNF141 RNF122	4.66e-04	172	149	7	IPR018957
Domain	-	ADAM22 AMZ2 ADAMTS9 ADAMTS18 ADAMTS20	4.75e-04	81	149	5	3.40.390.10
Domain	MetalloPept_cat_dom	ADAM22 AMZ2 ADAMTS9 ADAMTS18 ADAMTS20	4.75e-04	81	149	5	IPR024079
Domain	zf-MYND	ZMYND11 DEAF1 CBFA2T2	5.96e-04	21	149	3	PF01753
Domain	EGF_CA	LRP8 CRELD1 UMOD EGFL8 NOTCH4	6.26e-04	86	149	5	PF07645
Domain	ZF_RING_2	AMFR RNF148 TRIM34 TRIM6 RNF150 KMT2C RNF141 RNF122 TRIM38	6.60e-04	298	149	9	PS50089
Domain	ZF_MYND_1	ZMYND11 DEAF1 CBFA2T2	6.86e-04	22	149	3	PS01360
Domain	Znf_MYND	ZMYND11 DEAF1 CBFA2T2	6.86e-04	22	149	3	IPR002893
Domain	ZF_MYND_2	ZMYND11 DEAF1 CBFA2T2	6.86e-04	22	149	3	PS50865
Domain	PHD	DPF1 ZMYND11 NSD2 KMT2C PHF13	7.32e-04	89	149	5	SM00249
Domain	zf-RING_2	AMFR RNF148 RNF150 RNF122	7.82e-04	52	149	4	PF13639
Domain	ADAM_spacer1	ADAMTS9 ADAMTS18 ADAMTS20	7.84e-04	23	149	3	IPR010294
Domain	ADAM_spacer1	ADAMTS9 ADAMTS18 ADAMTS20	7.84e-04	23	149	3	PF05986
Domain	Znf_PHD	DPF1 ZMYND11 NSD2 KMT2C PHF13	8.10e-04	91	149	5	IPR001965
Domain	Peptidase_M12B_ADAM-TS	ADAMTS9 ADAMTS18 ADAMTS20	8.91e-04	24	149	3	IPR013273
Domain	PET	LMCD1 PRICKLE3	9.29e-04	6	149	2	PF06297
Domain	PET_domain	LMCD1 PRICKLE3	9.29e-04	6	149	2	IPR010442
Domain	PET	LMCD1 PRICKLE3	9.29e-04	6	149	2	PS51303
Domain	ZF_PHD_2	DPF1 ZMYND11 NSD2 KMT2C PHF13	9.84e-04	95	149	5	PS50016
Domain	DHHC	ZDHHC4 KMT2C ZDHHC11	1.01e-03	25	149	3	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC4 KMT2C ZDHHC11	1.01e-03	25	149	3	IPR001594
Domain	ZF_PHD_1	DPF1 ZMYND11 NSD2 KMT2C PHF13	1.03e-03	96	149	5	PS01359
Domain	EGF_Ca-bd_CS	LRP8 CRELD1 UMOD EGFL8 NOTCH4	1.08e-03	97	149	5	IPR018097
Domain	EGF_CA	LRP8 CRELD1 UMOD EGFL8 NOTCH4	1.18e-03	99	149	5	PS01187
Domain	ASX_HYDROXYL	LRP8 CRELD1 UMOD EGFL8 NOTCH4	1.24e-03	100	149	5	PS00010
Domain	Glyco_hydro_22_lys	LYZL1 LYZL2	1.29e-03	7	149	2	IPR000974
Domain	Glyco_hydro_22_CS	LYZL1 LYZL2	1.29e-03	7	149	2	IPR019799
Domain	ARF	ARL5A ARL5C ARL2	1.56e-03	29	149	3	PS51417
Domain	Small_GTPase_ARF	ARL5A ARL5C ARL2	1.56e-03	29	149	3	IPR024156
Domain	FYVE	MTMR4 MTMR3 FGD6	1.56e-03	29	149	3	PF01363
Domain	FYVE	MTMR4 MTMR3 FGD6	1.56e-03	29	149	3	SM00064
Domain	EGF-type_Asp/Asn_hydroxyl_site	LRP8 CRELD1 UMOD EGFL8 NOTCH4	1.60e-03	106	149	5	IPR000152
Domain	TSP_1	THSD7A ADAMTS9 ADAMTS18 ADAMTS20	1.61e-03	63	149	4	PF00090
Domain	Glyco_hydro_22	LYZL1 LYZL2	1.72e-03	8	149	2	IPR001916
Domain	LACTALBUMIN_LYSOZYME_2	LYZL1 LYZL2	1.72e-03	8	149	2	PS51348
Domain	Lys	LYZL1 LYZL2	1.72e-03	8	149	2	PF00062
Domain	LACTALBUMIN_LYSOZYME_1	LYZL1 LYZL2	1.72e-03	8	149	2	PS00128
Domain	LYZ1	LYZL1 LYZL2	1.72e-03	8	149	2	SM00263
Domain	TSP1	THSD7A ADAMTS9 ADAMTS18 ADAMTS20	1.81e-03	65	149	4	SM00209
Domain	TSP1_rpt	THSD7A ADAMTS9 ADAMTS18 ADAMTS20	1.81e-03	65	149	4	IPR000884
Domain	TSP1	THSD7A ADAMTS9 ADAMTS18 ADAMTS20	1.81e-03	65	149	4	PS50092
Domain	Arf	ARL5A ARL5C ARL2	1.90e-03	31	149	3	PF00025
Domain	Plexin_cytopl	PLXNA3 PLXNA4	2.19e-03	9	149	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA3 PLXNA4	2.19e-03	9	149	2	IPR013548
Domain	Plexin	PLXNA3 PLXNA4	2.19e-03	9	149	2	IPR031148
Domain	Small_GTPase_ARF/SAR	ARL5A ARL5C ARL2	2.28e-03	33	149	3	IPR006689
Domain	ZF_RING_1	AMFR RNF148 TRIM34 TRIM6 RNF150 RNF141 RNF122 TRIM38	2.36e-03	291	149	8	PS00518
Domain	Znf_FYVE-rel	MTMR4 MTMR3 FGD6	2.48e-03	34	149	3	IPR017455
Domain	Na_channel_asu	SCN11A SCN7A	2.73e-03	10	149	2	IPR001696
Domain	Na_trans_assoc	SCN11A SCN7A	2.73e-03	10	149	2	IPR010526
Domain	Na_trans_assoc	SCN11A SCN7A	2.73e-03	10	149	2	PF06512
Domain	Lysozyme-like_dom	LYZL1 LYZL2	2.73e-03	10	149	2	IPR023346
Domain	EGF_CA	LRP8 CRELD1 UMOD EGFL8 NOTCH4	2.96e-03	122	149	5	SM00179
Domain	EGF-like_Ca-bd_dom	LRP8 CRELD1 UMOD EGFL8 NOTCH4	3.18e-03	124	149	5	IPR001881
Domain	EGF	LRP8 MALRD1 UMOD EGFL8 NOTCH4	3.41e-03	126	149	5	PF00008
Domain	Znf_FYVE	MTMR4 MTMR3 FGD6	3.42e-03	38	149	3	IPR000306
Pathway	REACTOME_RAS_PROCESSING	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 ARL2 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	7.54e-29	45	114	19	MM15671
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-14	191	114	18	MM15289
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.73e-13	221	114	18	M27578
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	3.18e-12	262	114	18	MM15286
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 ARL2 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	8.80e-12	318	114	19	MM15278
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.90e-11	299	114	18	M27574
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	AMFR USP17L21 USP17L4 GOLGA8J USP17L2 THSD7A USP17L12 USP17L1 RBBP5 USP17L20 USP17L11 NUP98 USP17L5 ST3GAL1 USP17L10 USP17L19 TF USP17L18 AAAS USP17L17 ADAMTS9 GOLGA8H USP17L6P USP17L3 ADAMTS18 ADAMTS20 UMOD FBXO32 USP17L22 MUC2 USP17L15 USP17L8 USP17L13	7.77e-09	1389	114	33	MM15307
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	AMFR USP17L21 USP17L4 USP17L2 THSD7A USP17L12 USP17L1 RBBP5 USP17L20 USP17L11 USP17L24 NUP98 USP17L5 ST3GAL1 USP17L10 USP17L19 TF CREBBP USP17L18 AAAS USP17L17 ADAMTS9 USP17L3 ADAMTS18 ADAMTS20 UMOD FBXO32 USP17L22 USP17L15 USP17L8 USP17L13	4.12e-07	1475	114	31	M19806
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD7A ADAMTS9 ADAMTS18 ADAMTS20 NOTCH4	2.20e-04	68	114	5	M27303
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD7A ST3GAL1 ADAMTS9 ADAMTS18 ADAMTS20 MUC2	2.52e-04	109	114	6	MM15164
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTS9 ADAMTS18 ADAMTS20	2.68e-04	39	114	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD7A ADAMTS9 ADAMTS18 ADAMTS20	2.68e-04	39	114	4	MM15165
Pathway	WP_PHOSPHOINOSITIDES_METABOLISM	MTMR4 PIK3C2A PIP4P1 MTMR3	6.49e-04	49	114	4	M40046
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 NUP98 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	3.24e-41	24	156	19	8995226
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.57e-40	21	156	18	8622927
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.57e-40	21	156	18	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.57e-40	21	156	18	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.57e-40	21	156	18	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.57e-40	21	156	18	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.57e-40	21	156	18	18980247
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.41e-39	22	156	18	9154835
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	9.16e-38	25	156	18	21115691
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.97e-37	26	156	18	35816173
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	6.04e-37	33	156	19	20228807
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	20403174
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	14699124
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	15780755
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	11941478
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	17109758
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	20388806
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	20715989
Pubmed	Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	9806828
Pubmed	The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	20368735
Pubmed	The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	10936051
Pubmed	The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.36e-36	34	156	19	21448158
Pubmed	Cytokine-regulated protein degradation by the ubiquitination system.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.97e-36	35	156	19	16611142
Pubmed	Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.97e-36	35	156	19	21239494
Pubmed	The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	6.27e-36	36	156	19	20147298
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	6.50e-36	29	156	18	32527007
Pubmed	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	1.28e-35	37	156	19	20228808
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	3.13e-30	50	156	18	31806660
Pubmed	High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8	3.78e-15	10	156	7	24207026
Pubmed	Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8	2.48e-14	12	156	7	24695638
Pubmed	ES cell neural differentiation reveals a substantial number of novel ESTs.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8	1.07e-13	14	156	7	11793228
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8	1.54e-12	19	156	7	28067227
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 TMPRSS5 USP17L10 USP17L19 USP17L18 USP17L17 PLXNA4 USP17L6P USP17L3 USP17L22 GPAT2 USP17L15 USP17L8 USP17L13	3.76e-12	674	156	21	37196079
Pubmed	A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.	USP17L21 USP17L12 USP17L20 USP17L11 USP17L19 USP17L18 USP17L17 ASMT	7.04e-08	119	156	8	28625976
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP17L4 USP17L2 USP17L1 USP17L6P USP17L3 USP17L15 USP17L8	8.40e-08	81	156	7	12838346
Pubmed	Embryonic demise caused by targeted disruption of a cysteine protease Dub-2.	USP17L2 USP17L15 USP17L13	3.53e-07	4	156	3	22984479
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	AMFR TRIM34 UBE4A RNF150 RNF122 TRIM38	1.61e-05	118	156	6	19690564
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS9 ADAMTS18 ADAMTS20	1.89e-05	12	156	3	25770910
Pubmed	ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.	ZDHHC11B ZDHHC11	2.00e-05	2	156	2	28331227
Pubmed	Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions.	BNC2 BNC1	2.00e-05	2	156	2	16891417
Pubmed	Enhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance.	INSR TF	2.00e-05	2	156	2	32382087
Pubmed	Activation of a muscle-specific enhancer by the Ski proto-oncogene.	MYOD1 SKI	2.00e-05	2	156	2	7659522
Pubmed	The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.	CFC1 CFC1B	2.00e-05	2	156	2	11174844
Pubmed	Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction.	TRIM34 TRIM6	2.00e-05	2	156	2	24314652
Pubmed	Testis-specific hnRNP is expressed in colorectal cancer cells and accelerates cell growth mediating ZDHHC11 mRNA stabilization.	ZDHHC11B ZDHHC11	2.00e-05	2	156	2	35384384
Pubmed	Discordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals.	TRIM34 TRIM6	2.00e-05	2	156	2	18159944
Pubmed	Decreased Expression of BNC1 and BNC2 Is Associated with Genetic or Epigenetic Regulation in Hepatocellular Carcinoma.	BNC2 BNC1	2.00e-05	2	156	2	26821013
Pubmed	The multifunctional role of the co-activator CBP in transcriptional regulation.	MYOD1 CREBBP	2.00e-05	2	156	2	9238849
Pubmed	Molecular cloning and expression analysis of the mouse Spot-2 gene in pituitary development.	LHX4 LHX3	2.00e-05	2	156	2	12684778
Pubmed	Lhx4 surpasses its paralog Lhx3 in promoting the differentiation of spinal V2a interneurons.	LHX4 LHX3	2.00e-05	2	156	2	38970652
Pubmed	Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.	ADAMTS9 ADAMTS20	2.00e-05	2	156	2	12514189
Pubmed	Nomenclature of voltage-gated sodium channels.	SCN11A SCN7A	2.00e-05	2	156	2	11144347
Pubmed	Pathophysiology of syndromic combined pituitary hormone deficiency due to a LHX3 defect in light of LHX3 and LHX4 expression during early human development.	LHX4 LHX3	2.00e-05	2	156	2	15567726
Pubmed	Intrinsic flexibility of NLRP pyrin domains is a key factor in their conformational dynamics, fold stability, and dimerization.	NLRP14 NLRP4	2.00e-05	2	156	2	25403012
Pubmed	Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.	CFC1 CFC1B	2.00e-05	2	156	2	11327798
Pubmed	Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.	PLXNA3 PLXNA4	2.00e-05	2	156	2	24619647
Pubmed	Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.	CFC1 CFC1B	2.00e-05	2	156	2	11024280
Pubmed	Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.	CFC1 CFC1B	2.00e-05	2	156	2	11062482
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	DPF1 RBBP5 KDM3B SKI CREBBP ARID1B SAP130 MED12	3.04e-05	268	156	8	33640491
Pubmed	Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.	RBBP5 CREBBP KMT2C	3.11e-05	14	156	3	12482968
Pubmed	Maternal Cripto is critical for proper development of the mouse placenta and the placental vasculature.	CFC1 CFC1B NOTCH4	3.87e-05	15	156	3	33730615
Pubmed	The mouse germ-cell-specific leucine-rich repeat protein NALP14: a member of the NACHT nucleoside triphosphatase family.	NLRP14 NLRP4	5.98e-05	3	156	2	15590904
Pubmed	Mitogen-activated protein kinase kinase 1 (MEK1) stabilizes MyoD through direct phosphorylation at tyrosine 156 during myogenic differentiation.	MYOD1 FBXO32	5.98e-05	3	156	2	21454680
Pubmed	Molecular cloning of ring finger protein 21 (RNF21)/interferon-responsive finger protein (ifp1), which possesses two RING-B box-coiled coil domains in tandem.	TRIM34 TRIM6	5.98e-05	3	156	2	11013086
Pubmed	Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex.	PLXNA3 PLXNA4	5.98e-05	3	156	2	18523013
Pubmed	ZDHHC19 localizes to the cell membrane of spermatids and is involved in spermatogenesis†.	ZDHHC11B ZDHHC11	5.98e-05	3	156	2	34897408
Pubmed	Identification of a conserved protein that interacts with specific LIM homeodomain transcription factors.	LHX4 LHX3	5.98e-05	3	156	2	10788441
Pubmed	Comparison of the expression patterns of two LIM-homeodomain genes, Lhx6 and L3/Lhx8, in the developing palate.	LHX3 LHX8	5.98e-05	3	156	2	12086327
Pubmed	CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity.	NUP98 CREBBP	5.98e-05	3	156	2	9858599
Pubmed	Mediator modulates Gli3-dependent Sonic hedgehog signaling.	CREBBP MED12	5.98e-05	3	156	2	17000779
Pubmed	Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.	CFC1 CFC1B	5.98e-05	3	156	2	16835440
Pubmed	c-Ski activates MyoD in the nucleus of myoblastic cells through suppression of histone deacetylases.	MYOD1 SKI	5.98e-05	3	156	2	17352741
Pubmed	A new Adamts9 conditional mouse allele identifies its non-redundant role in interdigital web regression.	ADAMTS9 ADAMTS20	5.98e-05	3	156	2	24753090
Pubmed	PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking.	MTMR4 MTMR3	5.98e-05	3	156	2	30944173
Pubmed	Expression and function of the LIM homeobox containing genes Lhx3 and Lhx4 in the mouse placenta.	LHX4 LHX3	5.98e-05	3	156	2	18425848
Pubmed	KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells.	RBBP5 CREBBP	5.98e-05	3	156	2	36893259
Pubmed	Degradomic Identification of Membrane Type 1-Matrix Metalloproteinase as an ADAMTS9 and ADAMTS20 Substrate.	ADAMTS9 ADAMTS20	5.98e-05	3	156	2	37169079
Pubmed	FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphotidylinositol 3-phosphate.	MTMR4 MTMR3	5.98e-05	3	156	2	11302699
Pubmed	DNA sequence and analysis of human chromosome 8.	USP17L4 USP17L1 USP17L3 USP17L8	6.50e-05	48	156	4	16421571
Pubmed	Rap2 function requires palmitoylation and recycling endosome localization.	GOLGA8J TF GOLGA8H	1.11e-04	21	156	3	19061864
Pubmed	Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment.	GOLGA8J TF GOLGA8H	1.11e-04	21	156	3	15229288
Pubmed	Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C.	MYOD1 CREBBP	1.19e-04	4	156	2	9001254
Pubmed	Differential roles of p300 and PCAF acetyltransferases in muscle differentiation.	MYOD1 CREBBP	1.19e-04	4	156	2	9659901
Pubmed	ZDHHC11 modulates innate immune response to DNA virus by mediating MITA-IRF3 association.	ZDHHC11B ZDHHC11	1.19e-04	4	156	2	29429998
Pubmed	Alpha7 integrin expression is negatively regulated by deltaEF1 during skeletal myogenesis.	MYOD1 ITGA7	1.19e-04	4	156	2	16129691
Pubmed	An expanded clade of rodent Trim5 genes.	TRIM34 TRIM6	1.19e-04	4	156	2	19147168
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA3 PLXNA4	1.19e-04	4	156	2	11306810
Pubmed	Interaction between acetylated MyoD and the bromodomain of CBP and/or p300.	MYOD1 CREBBP	1.19e-04	4	156	2	11463815
Pubmed	Cripto in tumors and embryo development.	CFC1 CFC1B	1.19e-04	4	156	2	11825688
Pubmed	Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins.	PLXNA3 PLXNA4	1.19e-04	4	156	2	15721238
Pubmed	Antiretroviral potential of human tripartite motif-5 and related proteins.	TRIM34 TRIM6	1.19e-04	4	156	2	16828831
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA3 PLXNA4	1.19e-04	4	156	2	25518740
Pubmed	Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification.	LHX4 LHX3	1.19e-04	4	156	2	22025611
Pubmed	KDM3B is the H3K9 demethylase involved in transcriptional activation of lmo2 in leukemia.	KDM3B CREBBP	1.19e-04	4	156	2	22615488
Pubmed	CREB-binding protein/p300 activates MyoD by acetylation.	MYOD1 CREBBP	1.19e-04	4	156	2	10944526
Pubmed	Role of the EGF-CFC gene cripto in cell differentiation and embryo development.	CFC1 CFC1B	1.19e-04	4	156	2	11992720
Pubmed	Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma.	NSD2 CREBBP	1.19e-04	4	156	2	33589584
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	CREBBP KMT2C	1.19e-04	4	156	2	28398509
Pubmed	Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.	ADAMTS9 ADAMTS18	1.19e-04	4	156	2	16507336
Cytoband	4p16.1	USP17L21 USP17L12 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P ABLIM2 USP17L22 USP17L15 USP17L13	1.89e-22	79	155	15	4p16.1
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	USP17L21 USP17L12 USP17L20 NSD2 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P ABLIM2 USP17L22 USP17L15 USP17L13	6.81e-17	222	155	16	chr4p16
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	DEAF1 MYOD1 NUP98 TRIM34 TRIM6 NLRP14 PIK3C2A RNF141 MUC2 OTOG	2.42e-05	564	155	10	chr11p15
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	USP17L4 USP17L2 USP17L1 FBXO25 USP17L3 USP17L8	1.53e-04	234	155	6	chr8p23
Cytoband	8p23.1	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	1.85e-04	154	155	5	8p23.1
GeneFamily	LIM class homeoboxes	LHX4 LHX3 LHX8	3.92e-05	12	104	3	522
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS9 ADAMTS18 ADAMTS20	1.68e-04	19	104	3	50
GeneFamily	PHD finger proteins	DPF1 ZMYND11 NSD2 KMT2C PHF13	1.71e-04	90	104	5	88
GeneFamily	Ring finger proteins	AMFR RNF148 TRIM34 TRIM6 RNF150 RNF141 RNF122 TRIM38	1.89e-04	275	104	8	58
GeneFamily	Zinc fingers MYND-type	ZMYND11 DEAF1 CBFA2T2	2.28e-04	21	104	3	87
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF132 BNC2 ZNF311 ZNF155 ZBTB41 ZNF224 ZBTB42 ZNF692 ZNF461 BNC1 CTCFL ZNF330 ZNF264	2.40e-04	718	104	13	28
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC11B ZDHHC4 ZDHHC11	3.43e-04	24	104	3	76
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	MTMR4 MTMR3 FGD6	7.39e-04	31	104	3	81
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	ARL5A ARL5C ARL2	7.39e-04	31	104	3	357
GeneFamily	Phosphoinositide phosphatases	MTMR4 PIP4P1 MTMR3	8.12e-04	32	104	3	1079
GeneFamily	Lysozymes, c-type	LYZL1 LYZL2	1.15e-03	9	104	2	1174
GeneFamily	Plexins	PLXNA3 PLXNA4	1.15e-03	9	104	2	683
GeneFamily	Cyclins\|F-boxes other	FBXO25 FBXO32 FBXO45	1.45e-03	39	104	3	560
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR4 MTMR3	3.28e-03	15	104	2	903
GeneFamily	WD repeat domain containing	RBBP5 WDR55 AMBRA1 AAAS EML5 WDR86	4.06e-03	262	104	6	362
GeneFamily	LIM domain containing	LMCD1 PRICKLE3 ABLIM2	4.76e-03	59	104	3	1218
GeneFamily	PWWP domain containing	ZMYND11 NSD2	7.02e-03	22	104	2	1147
GeneFamily	NLR family	NLRP14 NLRP4	9.02e-03	25	104	2	666
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	NLRP14 NLRP4	9.02e-03	25	104	2	994
Coexpression	MADAN_DPPA4_TARGETS	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	2.72e-23	86	154	18	MM1312
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	4.44e-21	112	154	18	MM1095
Coexpression	GERY_CEBP_TARGETS	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	3.38e-18	160	154	18	MM1155
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L19 PPM1B USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 ARAP2 USP17L8 USP17L13	1.54e-09	647	154	20	MM981
Coexpression	MARSON_BOUND_BY_FOXP3_STIMULATED	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 SSMEM1 USP17L5 USP17L10 USP17L19 RGS3 AMZ2 USP17L18 DAP3 USP17L17 ZNF330 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	7.93e-08	1072	154	23	MM1031
Coexpression	GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L5 TRIM34 USP17L10 USP17L19 GFER PPM1B USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 ARAP2 USP17L8 USP17L13	3.06e-06	1226	154	22	MM979
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 LMCD1 ADAM22 SSC5D PLXNA4 WDR86 FBXO32	2.83e-06	183	149	7	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	BNC2 LMCD1 DGKB ITGA7 AOPEP PLXNA4 FBXO32	3.27e-06	187	149	7	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	3.38e-06	188	149	7	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	BNC2 LMCD1 RNF150 SSC5D PLXNA4 FBXO32 PLP1	3.63e-06	190	149	7	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD7A INSR N4BP3 RGS3 ADAMTS9 EGFL8 NOTCH4	4.45e-06	196	149	7	ae46d4b00be92e64e46252dcc156161b171eded4
ToppCell	15-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	LMCD1 RNF150 SSC5D AOPEP PLXNA4 FBXO32 PLP1	4.45e-06	196	149	7	0e45817625b96d21a8cc4dfbbd465ee6403b6802
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	4.92e-06	199	149	7	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	4.92e-06	199	149	7	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	4.92e-06	199	149	7	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	5.08e-06	200	149	7	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	5.08e-06	200	149	7	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	5.08e-06	200	149	7	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	5.08e-06	200	149	7	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 LMCD1 SCN7A PLXNA4 WDR86 FBXO32	2.05e-05	166	149	6	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF692 ARL5A LRP8 EML5 WDR86 PHF13	2.84e-05	176	149	6	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARL5A LRP8 ARL5C EML5 WDR86 PHF13	2.94e-05	177	149	6	f360f7099570d248531897b96e0de282e58f59e9
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BNC2 BNC1 ADAMTS9 CFC1 CFC1B TMEM151A	2.94e-05	177	149	6	0912a291cff32a4ff8a2d7680ed1a1cd867fb90f
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THSD7A LMCD1 INSR PIK3C2A ADAMTS9 NOTCH4	3.13e-05	179	149	6	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BNC2 LMCD1 RNF150 PLXNA4 FBXO32 PLP1	3.33e-05	181	149	6	25915e2500430a902db37d79a749ce2990b69810
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 LMCD1 ADAM22 RNF150 PLXNA4 FBXO32	3.76e-05	185	149	6	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 LMCD1 ADAM22 SSC5D PLXNA4 FBXO32	3.76e-05	185	149	6	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 ARHGEF25 ADAM22 SSC5D PLXNA4 FBXO32	3.76e-05	185	149	6	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BNC2 BNC1 ADAMTS9 CFC1 PLXNA4 TMEM151A	4.11e-05	188	149	6	e2bee29865805d4db30b090d4bce9a1f5311cf51
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMPRSS5 ITGA7 CTCFL SCN7A EGFL8 PLP1	4.11e-05	188	149	6	502045a39ffb1e92bd9499848368e8fa971edb88
ToppCell	facs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOD1 TMPRSS5 ACTN3 ITGA7 ADAMTS20 PLP1	4.11e-05	188	149	6	794fc1d9a726945c42f7eac221eed938309b47a9
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD7A N4BP3 RGS3 ADAMTS9 EGFL8 NOTCH4	4.23e-05	189	149	6	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LMCD1 ITGA7 ARHGEF25 ADAM22 SSC5D FBXO32	4.62e-05	192	149	6	992d08092edbc68c47b945deb8708379738c239a
ToppCell	IPF-Epithelial-Mesothelial\|Epithelial / Disease state, Lineage and Cell class	BNC2 BNC1 ADAMTS9 PLXNA4 TMEM151A ABLIM2	4.90e-05	194	149	6	d8a26da856a85e3d001d406e992cb18fdd58baef
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	LMCD1 SSC5D AOPEP PLXNA4 FBXO32 PLP1	5.04e-05	195	149	6	4dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	LMCD1 SSC5D AOPEP PLXNA4 FBXO32 PLP1	5.18e-05	196	149	6	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	LMCD1 SSC5D AOPEP PLXNA4 FBXO32 PLP1	5.48e-05	198	149	6	2d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCell	tumor_Lung-Endothelial_cells-Tumor_ECs\|tumor_Lung / Location, Cell class and cell subclass	THSD7A LMCD1 INSR ADAMTS9 ADAMTS18 NOTCH4	5.48e-05	198	149	6	5228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ARHGEF25 TF RGS3 ADAMTS9 WDR86 FBXO32	5.48e-05	198	149	6	a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ARHGEF25 TF RGS3 ADAMTS9 WDR86 FBXO32	5.48e-05	198	149	6	8b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 DGKB ITGA7 RGS3 RNF150 FBXO32	5.48e-05	198	149	6	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ARHGEF25 TF RGS3 ADAMTS9 WDR86 FBXO32	5.48e-05	198	149	6	4739b2e4ab141c66772e61686b45614a1839483e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 ADAM22 SSC5D FBXO32 PLP1	5.80e-05	200	149	6	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LMCD1 DGKB ITGA7 RNF150 ADAMTS9 FBXO32	5.80e-05	200	149	6	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 PTGFR SSC5D PLXNA4 FBXO32	5.80e-05	200	149	6	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LMCD1 ADAM22 SSC5D PLXNA4 FBXO32 PLP1	5.80e-05	200	149	6	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	DPF1 SCN11A SKI TMEM259 PLP1 PHF13	5.80e-05	200	149	6	a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	LMCD1 ADAM22 SSC5D PLXNA4 WDR86 FBXO32	5.80e-05	200	149	6	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LMCD1 ARHGEF25 SSC5D PLXNA4 FBXO32 PLP1	5.80e-05	200	149	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-2\|TCGA-Bladder / Sample_Type by Project: Shred V9	DGKB PTGFR RNF150 SCN7A PLP1	1.12e-04	141	149	5	1baa054c2ae3b446d1954244b7fbf8af824ef345
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 USP17L17 USP17L6P USP17L3 USP17L22 USP17L15 USP17L8 USP17L13	3.39e-32	46	151	19	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L19 USP17L18 KMT2C USP17L17 USP17L6P USP17L3 USP17L22 SAP130 USP17L15 USP17L8 USP17L13	4.01e-32	69	151	21	DOID:1682 (implicated_via_orthology)
Disease	double outlet right ventricle (implicated_via_orthology)	CFC1 CFC1B	7.78e-05	3	151	2	DOID:6406 (implicated_via_orthology)
Disease	dextro-looped transposition of the great arteries (implicated_via_orthology)	CFC1 CFC1B	1.55e-04	4	151	2	DOID:0060770 (implicated_via_orthology)
Disease	right atrial isomerism (implicated_via_orthology)	CFC1 CFC1B	1.55e-04	4	151	2	DOID:0060856 (implicated_via_orthology)
Disease	Combined pituitary hormone deficiencies, genetic form	LHX4 LHX3	2.58e-04	5	151	2	cv:C4273747
Disease	panhypopituitarism (is_implicated_in)	LHX4 LHX3	5.37e-04	7	151	2	DOID:9410 (is_implicated_in)
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR4 MTMR3	9.15e-04	9	151	2	DOID:0111225 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN11A SCN7A	1.14e-03	10	151	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN11A SCN7A	1.14e-03	10	151	2	DOID:0080422 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	AMFR NSD2 MYOD1 NUP98 ZDHHC4 DAP3 ARID1B NLRP14 PRICKLE3 MTMR3 SLC28A1 MED12 CNR2 NOTCH4	1.28e-03	1074	151	14	C0006142
Disease	epilepsy (implicated_via_orthology)	SCN11A ITGA7 PRICKLE3 SCN7A ATP1A3	1.55e-03	163	151	5	DOID:1826 (implicated_via_orthology)
Disease	visceral heterotaxy (is_implicated_in)	CFC1 CFC1B	1.66e-03	12	151	2	DOID:0050545 (is_implicated_in)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN11A SCN7A	1.66e-03	12	151	2	DOID:0060170 (implicated_via_orthology)
Disease	dementia (is_implicated_in)	LRP8 NOTCH4	1.66e-03	12	151	2	DOID:1307 (is_implicated_in)
Disease	extrapulmonary tuberculosis	THSD7A DGKB	1.66e-03	12	151	2	MONDO_0000368
Disease	acute myeloid leukemia (implicated_via_orthology)	NUP98 CREBBP	1.66e-03	12	151	2	DOID:9119 (implicated_via_orthology)
Disease	Mental Depression	DEAF1 DGKB ASMT ATP1A3 MED12 CNR2	2.02e-03	254	151	6	C0011570
Disease	dystonia (is_implicated_in)	AOPEP TMEM151A	2.27e-03	14	151	2	DOID:543 (is_implicated_in)
Disease	forced expiratory volume	BNC2 THSD7A DGKB LHX3 ACTN3 SKI PTGFR SSC5D PLXNA4 FGD6 PHF13	2.54e-03	789	151	11	EFO_0004314
Disease	filaggrin gene expression measurement	RGS3 RNF150	2.98e-03	16	151	2	EFO_0020899
Disease	cognitive behavioural therapy	ARL5A SCN7A ABLIM2	3.30e-03	58	151	3	EFO_0007820
Disease	pre-malignant neoplasm (biomarker_via_orthology)	INSR MUC2	3.36e-03	17	151	2	DOID:0060071 (biomarker_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	DPF1 KDM3B CREBBP ARID1B ATP1A3	3.37e-03	195	151	5	DOID:1574 (implicated_via_orthology)
Disease	velopharyngeal dysfunction	BNC2 SLC28A1 UMOD FBXO45	3.63e-03	122	151	4	EFO_0009336
Disease	ischemia (biomarker_via_orthology)	ARID1B MUC2	3.77e-03	18	151	2	DOID:326 (biomarker_via_orthology)
Disease	Depressive disorder	DEAF1 DGKB ASMT ATP1A3 MED12 CNR2	3.82e-03	289	151	6	C0011581
Disease	Congenital hernia of foramen of Morgagni	MYOD1 INSR	4.20e-03	19	151	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	MYOD1 INSR	4.20e-03	19	151	2	C0265700

Protein segments in the cluster

Peptide	Gene	Start	Entry
SCCLRVFAWHPHTNK	AAAS	151	Q9NRG9
LCCASTTHDLRLHWG	BAAT	371	Q14032
WGGKHCHVDVDECRT	EGFL8	136	Q99944
SGLRRWLDHSKHCLS	ARHGEF25	76	Q86VW2
SIKDHQWHIQACCAL	ARL5A	146	Q9Y689
TIKDHSWHIQGCCAL	ARL5C	146	A6NH57
SRWINLHRHSEKCGS	CTCFL	556	Q8NI51
LRTCDQCKHGWVAHA	BNC2	131	Q6ZN30
SWSCHLCLRHLKEKA	DPF1	366	Q92782
CDQCKHGWVAHALSK	BNC1	56	Q01954
NELKCVCNRHWIGSD	ADAM22	696	Q9P0K1
ISHWKNCTRHDCPVC	CREBBP	416	Q92793
TCNECKHHVETRWHC	CREBBP	1706	Q92793
LVALDKHWHLGCFKC	ABLIM2	166	Q6H8Q1
HWQDSLAKRCICVSN	ARID1B	2006	Q8NFD5
EKHHWHLCCDSSRTQ	ARAP2	1511	Q8WZ64
IGHIFGLRHCQWLAC	AMZ2	256	Q86W34
HLCGTRLCHEIAHAW	AOPEP	471	Q8N6M6
TCLHWACKRNHGQVV	ANKRD40	46	Q6AI12
ARVLHDWADGKCSHL	ASMT	251	P46597
LEHGAWTLRACHLCR	CFC1B	126	P0CG36
KCVHSLIGHRRTPWC	AMBRA1	86	Q9C0C7
LEHGAWTLRACHLCR	CFC1	126	P0CG37
CKSLWCHRVGHRCET	ADAMTS18	541	Q8TE60
LRWHVIGKSECSSQC	ADAMTS20	906	P59510
IRSSAHHCLAHWKKC	CNR2	306	P34972
HHCLAHWKKCVRGLG	CNR2	311	P34972
ERGLHCSAVSCKNWL	RBFA	31	Q8N0V3
HWKCVELAHEIRSCP	RGS3	351	P49796
SIRSHHWCIQGCSAV	ARL2	146	P36404
CCKVIRHSLWGTHVV	MMADHC	261	Q9H3L0
RCSRVWGTTCTKHPH	PAPSS2	341	O95340
ESNCLQCKKGWALHH	CRELD1	226	Q96HD1
WALHHLKCVDIDECG	CRELD1	236	Q96HD1
CLFKAEHWNRCHKLI	NUP98	1636	P52948
CGTRSSSQWHHNCLI	KMT2C	441	Q8NEZ4
AWCRRGKLKENNHCH	LYZL1	81	Q6UWQ5
AWCRRGKLKENNHCH	LYZL2	81	Q7Z4W2
VIHDCRWLSDCLSHQ	EXD1	156	Q8NHP7
AALCQRHDWHTLCKD	IL17RE	301	Q8NFR9
KIFCARQNCSHDWGI	DDX58	861	O95786
CQHKDWERHHRLCGQ	CBFA2T2	531	O43439
QCCGVHVISLHIWEL	PTGFR	321	P43088
GWCISEHRCQLRTHC	PLXNA3	806	P51805
HCGWCVLHNTCTRKE	PLXNA4	526	Q9HCM2
HPDRSLSVCWEQHCK	L3MBTL1	721	Q9Y468
CLGSHEHIQNCRKWD	PIK3C2A	486	O00443
ICLDWRNHTHGACLV	MUC2	4746	Q02817
GHHQAGRCLLWACKA	MYOD1	86	P15172
WRAQCRCKHSHEEHA	FAM221B	326	A6H8Z2
HAHVNVSWCFVCSKG	NSD2	826	O96028
SHSWLCDGRLLCLHD	KDM3B	1381	Q7LBC6
ALDRHWHSKCLKCSD	LHX3	46	Q9UBR4
LDRHWHSSCLKCADC	LHX4	46	Q969G2
CSRCGRHIHSTDWVR	LHX8	136	Q68G74
LLCEWAVSCKRSGRH	MED12	506	Q93074
TLHFCRHCSILFWKD	FBXO25	316	Q8TCJ0
CWHHICSVLTTSGHL	NLRP4	626	Q96MN2
INGQFVERCWTHSHC	INSR	201	P06213
VERCWTHSHCQKVCP	INSR	206	P06213
GCDILKCHNWDAVRH	RICTOR	981	Q6R327
LAWHRKHFVCEGCEQ	LMCD1	326	Q9NZU5
EFWLAKRRHHCRNCG	MTMR4	1126	Q9NYA4
IHPVCSLCWSRDGHK	RBBP5	66	Q15291
CQDCWAGHQTHVLSK	IGF2BP2-AS1	56	Q96M15
VLCWVHSCGHEGHLR	GTSCR1	16	Q86UQ5
GFLLHGWRKICQHCK	PRICKLE3	36	O43900
LDHFWCRHTRACIEK	MALRD1	826	Q5VYJ5
KCQGDASRLCHTHGW	GLG1	566	Q92896
WSECLVTCGKGHKHR	ADAMTS9	1061	Q9P2N4
LVCKHWYRCLHGDEN	FBXO45	61	P0C2W1
TFCQRKDWKDHQHIC	DEAF1	526	O75398
WGCSHRICSRVHLAQ	GPAT2	366	Q6NUI2
WCQITLHNKCASHLK	DGKB	341	Q9Y6T7
KELCFIHHWRERCHQ	GOLGA8J	476	A6NMD2
KELCFIHHWRDRCHQ	GOLGA8H	476	P0CJ92
DAICCHTSTSKRHWL	TMEM259	391	Q4ZIN3
HTWVALSHIAGLCNR	ATP1A3	406	P13637
ASGTVWLKHQHDRVC	ITGA7	601	Q13683
ISGDVCVWKDHILCR	EML5	1581	Q05BV3
GDTLQLCKHCHILSW	FBXO32	311	Q969P5
LCKHCHILSWKGTDH	FBXO32	316	Q969P5
RVICGHCKNTFLWTE	PIP4P1	171	Q86T03
FTCDNGHCIHERWKC	LRP8	91	Q14114
AFWLASRKHHCRNCG	MTMR3	1131	Q13615
AHQCCQHGVAVDWRT	OTOG	1221	Q6ZRI0
HKSCVDPWLLDHRTC	RNF150	301	Q9ULK6
LSLCHVIHFCAKQDW	DAP3	136	P51398
CWLCERSQEHRGHHT	TRIM34	116	Q9BYJ4
ICWRCERAPQHKGHT	TRIM38	111	O00635
CAHVEGWTTLHTNCK	THSD7A	86	Q9UPZ6
RHCLHCKALRTNEWL	SSMEM1	196	Q8WWF3
CTHCIGQRKLSAWFD	ST3GAL1	61	Q11201
VCNWVVDTCLHKGSR	PPM1B	271	O75688
QSLGSSLCRESHWKC	TMEM151A	31	Q8N4L1
LGLCHHRGWKAHICS	SSC5D	96	A1L4H1
SHSRCWLLFRDGQCH	NOTCH4	1216	Q99466
VEHHKTCRSLGRSLW	URB1	1571	O60287
VHSHKALENRTCHWG	SKI	261	P12755
TTKWIKLHECRFHGC	STON2	636	Q8WXE9
TGKWSCVEERICHLQ	ANKRD20A12P	16	Q8NF67
CGHLFHNSCLRSWLE	AMFR	356	Q9UKV5
SWKDGLALCALIHRH	ACTN3	186	Q08043
RTRACFTQWLCHLHN	GFER	161	P55789
HASQGWLVRFKECHC	CENPBD1P	136	B2RD01
VRCIKCHKWGHVNTD	CIR1	126	Q86X95
CHKWGHVNTDRECPL	CIR1	131	Q86X95
ECHTWIHLSCAKIRK	PHF13	251	Q86YI8
WRSQIKCLHCHGISD	USP17L3	201	A6NCW0
KSSLICHWRVHTGER	ZNF132	611	P52740
VKWCALSHHERLKCD	TF	361	P02787
WRSQIKCLHCHGISD	USP17L4	201	A6NCW7
GIVSRKACAHWSGHC	UMOD	241	P07911
CQHAFHRKCLVKWLE	RNF122	111	Q9H9V4
HKACIDPWLLAHRTC	RNF148	281	Q8N7C7
HSFCQKCIDKWSDRH	RNF141	171	Q8WVD5
RSKHCSVCNWCVHRF	ZDHHC4	161	Q9NPG8
HIECTHGGKRKWTCF	ZBTB41	536	Q5SVQ8
CRAQGWKVHLCAAQL	SAP130	941	Q9H0E3
WRSQIKCLHCHGISD	USP17L18	201	D6R9N7
TLTWRRHHCRACGKI	FGD6	1236	Q6ZV73
WRSQIKCLHCHGISD	USP17L5	201	A8MUK1
QICWSLGHLRLTHHK	TMPRSS5	146	Q9H3S3
WRSQIKCLHCHGISD	USP17L21	201	D6R901
WRSQIKCLHCHGISD	USP17L13	201	C9JLJ4
WRSQIKCLHCHGISD	USP17L19	201	D6RCP7
CAWQTALCQHLHLTG	TSTD2	186	Q5T7W7
WRSQIKCLHCHGISD	USP17L1	201	Q7RTZ2
QHVRCQKCLEFGHWT	ZCCHC10	41	Q8TBK6
LLFACSKHHCAVSWR	SLC28A1	191	O00337
FDHHCKWINNCVGSR	ZDHHC11	151	Q9H8X9
TVVHTREKPHACRWC	ZBTB42	381	B2RXF5
CGKSFCWSTNLIRHA	ZNF264	516	O43296
WRSQIKCLHCHGISD	USP17L12	201	C9JPN9
WCTHVVALCLFRIHN	ZSWIM8	196	A7E2V4
CSIKCQQEHWHAEHK	ZMYND11	581	Q15326
WRSQIKCLHCHGISD	USP17L24	201	Q0WX57
ELWSSGHHLKACRAV	WDR55	76	Q9H6Y2
ECGKSFRWSSCLLNH	ZNF155	376	Q12901
WRSQIKCLHCHGISD	USP17L8	201	P0C7I0
FVCHIDKDCQLPRWH	SCN7A	656	Q01118
VRHTLEHFCHKWCRK	SCN11A	846	Q9UI33
AWVCHGRKCLSTHAC	ZNF330	106	Q9Y3S2
KHCILSWLGNCLHAN	UBE4A	396	Q14139
WRSQIKCLHCHGISD	USP17L6P	201	Q6QN14
WASCLLKHQRLHSGE	ZNF224	551	Q9NZL3
FDHHCKWINNCVGSR	ZDHHC11B	151	P0C7U3
WRSQIKCLHCHGISD	USP17L22	201	D6RA61
WRSQIKCLHCHGISD	USP17L15	201	C9J2P7
WRSQIKCLHCHGISD	USP17L17	201	D6RBQ6
KVWQVASGCCHQTLR	WDR86	176	Q86TI4
WRSQIKCLHCHGISD	USP17L2	201	Q6R6M4
CWLCERSQEHRGHHT	TRIM6	116	Q9C030
WRSQIKCLHCHGISD	USP17L20	201	D6RJB6
ICGFTCRQKASLNWH	ZNF692	421	Q9BU19
CWKAFVHCSQLKHLR	ZNF461	251	Q8TAF7
WRSQIKCLHCHGISD	USP17L10	201	C9JJH3
LHECARCGKNFSWHS	ZNF311	246	Q5JNZ3
RCGKNFSWHSDLILH	ZNF311	251	Q5JNZ3
WRSQIKCLHCHGISD	USP17L11	201	C9JVI0
KELCFIHHWRERCHQ	GOLGA8IP	476	A6NC78
DRITHCWQDLCSVLH	NLRP14	656	Q86W24
KLWRSNGSLHTLACH	N4BP3	141	O15049
QAHSLERVCHCLGKW	PLP1	131	P60201