Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribonucleoside-diphosphate reductase activity	RRM2B RRM1	5.23e-05	3	84	2	GO:0061731
GeneOntologyMolecularFunction	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	RRM2B RRM1	5.23e-05	3	84	2	GO:0004748
GeneOntologyMolecularFunction	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	RRM2B RRM1	1.73e-04	5	84	2	GO:0016728
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1F CACNA2D4 CATSPERD CACNA1I	3.32e-05	46	83	4	GO:0005891
GeneOntologyCellularComponent	ribonucleoside-diphosphate reductase complex	RRM2B RRM1	4.66e-05	3	83	2	GO:0005971
GeneOntologyCellularComponent	calcium channel complex	CACNA1F CACNA2D4 CATSPERD CACNA1I	2.04e-04	73	83	4	GO:0034704
Domain	ARM-type_fold	FOCAD CSE1L AP1G1 NBEA WDFY3 ARMCX2 USP9Y ARMC1 HTT SYMPK XPO7	2.34e-07	339	81	11	IPR016024
Domain	ARM-like	CSE1L AP1G1 NBEA WDFY3 ARMCX2 USP9Y ARMC1 HTT SYMPK XPO7	2.57e-07	270	81	10	IPR011989
Domain	-	CSE1L AP1G1 WDFY3 ARMCX2 ARMC1 HTT SYMPK	5.03e-05	222	81	7	1.25.10.10
Domain	VPS13_C	VPS13D VPS13B	1.11e-04	4	81	2	PF16909
Domain	SHR-BD	VPS13D VPS13B	1.11e-04	4	81	2	IPR009543
Domain	VPS13_C	VPS13D VPS13B	1.11e-04	4	81	2	IPR031645
Domain	SHR-BD	VPS13D VPS13B	1.11e-04	4	81	2	PF06650
Domain	Keratin_2_head	KRT3 KRT84 KRT79	1.49e-04	24	81	3	IPR032444
Domain	Keratin_2_head	KRT3 KRT84 KRT79	1.49e-04	24	81	3	PF16208
Domain	DUF4704	NBEA WDFY3	1.84e-04	5	81	2	IPR031570
Domain	DUF4704	NBEA WDFY3	1.84e-04	5	81	2	PF15787
Domain	Keratin_II	KRT3 KRT84 KRT79	1.90e-04	26	81	3	IPR003054
Domain	Acid_Pase_AS	ACP2 PPIP5K2	2.76e-04	6	81	2	IPR033379
Domain	Val/Leu/Ile-tRNA-synth_edit	IARS1 LARS1	2.76e-04	6	81	2	IPR009008
Domain	PH_BEACH	NBEA WDFY3	2.76e-04	6	81	2	PF14844
Domain	Anticodon_1	IARS1 LARS1	2.76e-04	6	81	2	PF08264
Domain	M/V/L/I-tRNA-synth_anticd-bd	IARS1 LARS1	2.76e-04	6	81	2	IPR013155
Domain	-	IARS1 LARS1	2.76e-04	6	81	2	3.90.740.10
Domain	aa-tRNA-synth_Ia	IARS1 LARS1	3.85e-04	7	81	2	IPR002300
Domain	HIS_ACID_PHOSPHAT_2	ACP2 PPIP5K2	3.85e-04	7	81	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	ACP2 PPIP5K2	3.85e-04	7	81	2	PS00616
Domain	tRNA-synt_1	IARS1 LARS1	3.85e-04	7	81	2	PF00133
Domain	PH-BEACH_dom	NBEA WDFY3	5.11e-04	8	81	2	IPR023362
Domain	VPS13_N	VPS13D VPS13B	5.11e-04	8	81	2	IPR026854
Domain	His_Pase_clade-2	ACP2 PPIP5K2	5.11e-04	8	81	2	IPR000560
Domain	His_Phos_2	ACP2 PPIP5K2	5.11e-04	8	81	2	PF00328
Domain	-	NBEA WDFY3	5.11e-04	8	81	2	2.30.29.40
Domain	VWA_3	VWA3A CACNA2D4	5.11e-04	8	81	2	PF13768
Domain	Chorein_N	VPS13D VPS13B	5.11e-04	8	81	2	PF12624
Domain	PH_BEACH	NBEA WDFY3	5.11e-04	8	81	2	PS51783
Domain	BEACH_dom	NBEA WDFY3	6.56e-04	9	81	2	IPR000409
Domain	BEACH	NBEA WDFY3	6.56e-04	9	81	2	PS50197
Domain	Beach	NBEA WDFY3	6.56e-04	9	81	2	PF02138
Domain	-	NBEA WDFY3	6.56e-04	9	81	2	1.10.1540.10
Domain	Beach	NBEA WDFY3	6.56e-04	9	81	2	SM01026
Domain	VDCCAlpha1	CACNA1F CACNA1I	8.17e-04	10	81	2	IPR002077
Domain	-	IARS1 LARS1	9.96e-04	11	81	2	1.10.730.10
Domain	IMPORTIN_B_NT	CSE1L XPO7	1.63e-03	14	81	2	PS50166
Domain	IBN_N	CSE1L XPO7	1.88e-03	15	81	2	PF03810
Domain	tRNAsynth_Ia_anticodon-bd	IARS1 LARS1	1.88e-03	15	81	2	IPR009080
Domain	IBN_N	CSE1L XPO7	2.14e-03	16	81	2	SM00913
Domain	Importin-beta_N	CSE1L XPO7	2.42e-03	17	81	2	IPR001494
Domain	PH_dom-like	GTF2H1 CDC42BPA DEF6 RALGPS2 NBEA WDFY3 EXOC8	2.49e-03	426	81	7	IPR011993
Domain	Intermediate_filament_CS	KRT3 KRT84 KRT79	2.59e-03	63	81	3	IPR018039
Domain	aa-tRNA-synth_I_CS	IARS1 LARS1	2.72e-03	18	81	2	IPR001412
Domain	AA_TRNA_LIGASE_I	IARS1 LARS1	3.03e-03	19	81	2	PS00178
Domain	His_PPase_superfam	ACP2 PPIP5K2	3.36e-03	20	81	2	IPR029033
Domain	-	ACP2 PPIP5K2	3.36e-03	20	81	2	3.40.50.1240
Domain	Filament	KRT3 KRT84 KRT79	3.63e-03	71	81	3	SM01391
Domain	IF	KRT3 KRT84 KRT79	3.78e-03	72	81	3	PS00226
Domain	Filament	KRT3 KRT84 KRT79	3.93e-03	73	81	3	PF00038
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FOCAD PTPRK ADAMTS9 DROSHA SYNE1 POLG LARS1 ADNP2 SESN3 MACF1 NBEA WDFY3 REV3L USP9Y PADI2 HMG20A EXOC4	9.88e-09	1285	84	17	35914814
Pubmed	Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13.	KRT3 KRT84 KRT79	1.13e-06	9	84	3	15737194
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AMER1 AP1G1 KRT84 POLG RALGPS2 MACF1 ACCSL PRAMEF13 PLA2G15 UBE2Q2 VPS13B KIAA0753 NCKAP1L	1.97e-06	1084	84	13	11544199
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	CSE1L AP1G1 IARS1 EXOC8 EXOC4 XPO7	5.65e-06	183	84	6	23956138
Pubmed	Investigation of the association of hRRM1 and p53R2 gene polymorphisms in head and neck squamous cell carcinomas.	RRM2B RRM1	5.76e-06	2	84	2	24861915
Pubmed	Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine.	RRM2B RRM1	5.76e-06	2	84	2	24215511
Pubmed	A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage.	RRM2B RRM1	5.76e-06	2	84	2	10716435
Pubmed	Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication.	RRM2B RRM1	5.76e-06	2	84	2	28416140
Pubmed	p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint.	RRM2B RRM1	5.76e-06	2	84	2	11719458
Pubmed	Clinical, pathological and genetic spectrum in 89 cases of mitochondrial progressive external ophthalmoplegia.	RRM2B POLG	1.73e-05	3	84	2	32161153
Pubmed	Ribonucleotide reductase expression in cervical cancer: a radiation therapy oncology group translational science analysis.	RRM2B RRM1	1.73e-05	3	84	2	23552804
Pubmed	SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.	EXOC8 EXOC4	1.73e-05	3	84	2	21658605
Pubmed	Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.	RRM2B RRM1	1.73e-05	3	84	2	18997010
Pubmed	Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion.	RRM2B RRM1	1.73e-05	3	84	2	17486094
Pubmed	In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase.	RRM2B RRM1	1.73e-05	3	84	2	14729598
Pubmed	α2δ-4 Is Required for the Molecular and Structural Organization of Rod and Cone Photoreceptor Synapses.	CACNA1F CACNA2D4	1.73e-05	3	84	2	29875267
Pubmed	Characterization of enzymatic properties of human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits.	RRM2B RRM1	1.73e-05	3	84	2	16376858
Pubmed	The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53.	RRM2B RRM1	3.45e-05	4	84	2	14583450
Pubmed	Analysis of the human VPS13 gene family.	VPS13D VPS13B	3.45e-05	4	84	2	15498460
Pubmed	Mouse all-cone retina models of Cav1.4 synaptopathy.	CACNA1F CACNA2D4	3.45e-05	4	84	2	37181655
Pubmed	Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase.	RRM2B RRM1	3.45e-05	4	84	2	20159953
Pubmed	Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells.	RRM2B RRM1	3.45e-05	4	84	2	11517226
Pubmed	Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits.	RRM2B RRM1	3.45e-05	4	84	2	12615712
Pubmed	Cellular apoptosis susceptibility gene capts maps to mouse chromosome 2.	CSE1L MC3R	3.45e-05	4	84	2	9545506
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPM6B CSE1L AP1G1 IARS1 SYNE1 MRPL48 LARS1 KIAA1549 MACF1 NBEA KRT79 DNAH6 EXOC4	3.78e-05	1431	84	13	37142655
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	VPS13D AMER1 CDC42BPA RALGPS2 MPDZ MACF1 PPIP5K2 NEK9 KIAA0753 EXOC4	4.34e-05	861	84	10	36931259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FOCAD SYNE1 MACF1 ZSWIM6 TRAK2 VPS13B XPO7	5.96e-05	407	84	7	12693553
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	GTF2H1 AMER1 CSE1L IARS1 RALGPS2 LARS1 PPIP5K2 NEK9 CCDC144A EXOC8 HMG20A EXOC4	7.75e-05	1321	84	12	27173435
Pubmed	Subunit structure of the mammalian exocyst complex.	EXOC8 EXOC4	8.59e-05	6	84	2	9405631
Pubmed	Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.	RRM2B HTT	8.59e-05	6	84	2	32876667
Pubmed	Arl13b and the exocyst interact synergistically in ciliogenesis.	EXOC8 EXOC4	8.59e-05	6	84	2	26582389
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 MACF1 KIAA0753 XPO7	1.08e-04	101	84	4	9872452
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	CSE1L IARS1 ACP2 ITGA3 ARIH1 RRM1 PLA2G15 FBXL5	1.20e-04	613	84	8	22268729
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TRAK2 ARMCX2 VPS13B CCDC144A	1.26e-04	105	84	4	9628581
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	CSE1L AP1G1 IARS1 LARS1 RRM1 NEK9 EXOC4 SYMPK	1.57e-04	638	84	8	33239621
Pubmed	Heat shock protein 90 mediates protein-protein interactions between human aminoacyl-tRNA synthetases.	IARS1 LARS1	1.60e-04	8	84	2	10913161
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1F CACNA1I	1.60e-04	8	84	2	28330839
Pubmed	Structural analysis of the high molecular mass aminoacyl-tRNA synthetase complex. Effects of neutral salts and detergents.	IARS1 LARS1	1.60e-04	8	84	2	1651330
Pubmed	Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1.	IARS1 LARS1	1.60e-04	8	84	2	36347866
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	VPS13D ADAMTS9 MACF1 ARMCX2 NEK9 KIAA0753 EXOC4	1.95e-04	493	84	7	15368895
Pubmed	A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.	CSE1L IARS1 LARS1 ITGA3	1.97e-04	118	84	4	27377895
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	CDC42BPA ADAMTS9 DROSHA SYNE1 MACF1 ARMCX2 NEK9	2.05e-04	497	84	7	23414517
Pubmed	The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene.	EXOC8 EXOC4	2.05e-04	9	84	2	11406615
Pubmed	The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin.	EXOC8 EXOC4	2.05e-04	9	84	2	12687004
Pubmed	Exorcising the exocyst complex.	EXOC8 EXOC4	2.05e-04	9	84	2	22420621
Pubmed	The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy.	WDFY3 HTT	2.05e-04	9	84	2	20417604
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1F CACNA1I	2.05e-04	9	84	2	16382099
Pubmed	Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments.	EXOC8 EXOC4	2.05e-04	9	84	2	9655500
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ZNF131 CDC42BPA SYNE1 MRPL48 KIAA1549 MPDZ MACF1 RRM1 VPS13B ARMC1 KIAA0753 EXOC4	2.34e-04	1487	84	12	33957083
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	AMER1 CDC42BPA POLG STYXL1 MACF1 ZSWIM6 ARIH1 NEK9 VPS13B HTT EXOC4 XPO7	2.37e-04	1489	84	12	28611215
Pubmed	The human EPRS locus (formerly the QARS locus): a gene encoding a class I and a class II aminoacyl-tRNA synthetase.	IARS1 LARS1	2.56e-04	10	84	2	8188258
Pubmed	The C-terminal appended domain of human cytosolic leucyl-tRNA synthetase is indispensable in its interaction with arginyl-tRNA synthetase in the multi-tRNA synthetase complex.	IARS1 LARS1	2.56e-04	10	84	2	16055448
Pubmed	Tetraspanin CD151 promotes cell migration by regulating integrin trafficking.	PRTG ITGA3	2.56e-04	10	84	2	17716972
Pubmed	Interplay between cell-adhesion molecules governs synaptic wiring of cone photoreceptors.	CACNA1F CACNA2D4	2.56e-04	10	84	2	32879010
Pubmed	The appended C-domain of human methionyl-tRNA synthetase has a tRNA-sequestering function.	IARS1 LARS1	2.56e-04	10	84	2	11714285
Pubmed	Ral GTPases regulate exocyst assembly through dual subunit interactions.	EXOC8 EXOC4	2.56e-04	10	84	2	14525976
Pubmed	Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib.	ARIH1 UBE2Q2	2.56e-04	10	84	2	33607208
Pubmed	Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit.	IARS1 LARS1	2.56e-04	10	84	2	8052601
Pubmed	Evolution of the Glx-tRNA synthetase family: the glutaminyl enzyme as a case of horizontal gene transfer.	IARS1 LARS1	2.56e-04	10	84	2	8078941
Pubmed	Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.	IARS1 LARS1	2.56e-04	10	84	2	22424946
Pubmed	Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescues Escherichia coli double-defective mutant.	IARS1 LARS1	2.56e-04	10	84	2	9278442
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	CSE1L CDC42BPA DROSHA SYNE1 MRPL48 MACF1 PPIP5K2 USP9Y HMG20A SYMPK	2.80e-04	1082	84	10	38697112
Pubmed	The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2.	TRAK2 ARMCX2	3.13e-04	11	84	2	22569362
Pubmed	Dynamic Organization of Aminoacyl-tRNA Synthetase Complexes in the Cytoplasm of Human Cells.	IARS1 LARS1	3.13e-04	11	84	2	19289464
Pubmed	Expression of human aspartyl-tRNA synthetase in Escherichia coli. Functional analysis of the N-terminal putative amphiphilic helix.	IARS1 LARS1	3.13e-04	11	84	2	8449960
Pubmed	The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.	CACNA1F CACNA2D4	3.13e-04	11	84	2	28262416
Pubmed	Dissection of the structural organization of the aminoacyl-tRNA synthetase complex.	IARS1 LARS1	3.13e-04	11	84	2	19131329
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	CSE1L CDC42BPA IARS1 LARS1 MPDZ MACF1 RRM1 EXOC4	3.17e-04	708	84	8	39231216
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	VPS13D CDC42BPA MACF1	3.43e-04	56	84	3	9455484
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	GTF2H1 DROSHA ADNP2 KIAA1549 MACF1 WDFY3 ITGA3 REV3L PADI2 HMG20A	3.57e-04	1116	84	10	31753913
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	GTF2H1 CSE1L AP1G1 IARS1 LARS1 ADNP2 MACF1 WDFY3 RRM1 NEK9 EXOC4	4.08e-04	1353	84	11	29467282
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FOCAD CACNA1F ADAMTS9 DROSHA IARS1 NBEA REV3L SYMPK	4.10e-04	736	84	8	29676528
Pubmed	Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein.	IARS1 LARS1	4.42e-04	13	84	2	9878398
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	CSE1L PTPRK AP1G1 IARS1 LARS1 EXOC8 EXOC4 SYMPK XPO7	4.52e-04	942	84	9	31073040
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	KRT3 CSE1L IARS1 KRT84 MRPL48 LARS1 MACF1 USP9Y RRM1 KRT79	4.61e-04	1153	84	10	29845934
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	KRT3 IARS1 KRT84 USP9Y KRT79	4.76e-04	266	84	5	19380743
Pubmed	New consensus nomenclature for mammalian keratins.	KRT3 KRT84 KRT79	4.86e-04	63	84	3	16831889
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SYNE1 MACF1 NBEA EXOC4	5.03e-04	151	84	4	17043677
Pubmed	p38 is essential for the assembly and stability of macromolecular tRNA synthetase complex: implications for its physiological significance.	IARS1 LARS1	5.15e-04	14	84	2	12060739
Pubmed	Human tyrosinase gene, mapped to chromosome 11 (q14----q21), defines second region of homology with mouse chromosome 7.	ACP2 RRM1	5.15e-04	14	84	2	3146546
Pubmed	Pellino-2 in nonimmune cells: novel interaction partners and intracellular localization.	MPDZ NEK9	5.15e-04	14	84	2	34674267
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	SYNE1 MACF1 REV3L HTT	5.16e-04	152	84	4	34299191
Pubmed	Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.	MPDZ EXOC4	5.93e-04	15	84	2	20237282
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1F CACNA2D4	5.93e-04	15	84	2	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1F CACNA2D4	5.93e-04	15	84	2	24453333
Pubmed	The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.	EXOC8 EXOC4	5.93e-04	15	84	2	24056301
Pubmed	Huntingtin: an iron-regulated protein essential for normal nuclear and perinuclear organelles.	HTT SYMPK	5.93e-04	15	84	2	11092755
Pubmed	Huntingtin interacts with a family of WW domain proteins.	HTT SYMPK	5.93e-04	15	84	2	9700202
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	AP1G1 IARS1 MRPL48 MACF1 ARIH1 HMG20A EXOC4	6.38e-04	601	84	7	33658012
Pubmed	Whole genome RNAi screens reveal a critical role of REV3 in coping with replication stress.	REV3L RRM1	6.77e-04	16	84	2	25113059
Pubmed	The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.	CSE1L IARS1 LARS1	6.90e-04	71	84	3	29346117
Pubmed	The human plasma proteome: a nonredundant list developed by combination of four separate sources.	IL15 CSE1L PTPRK MAPK7	7.02e-04	165	84	4	14718574
Pubmed	RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.	EXOC8 EXOC4	7.66e-04	17	84	2	21241894
Pubmed	Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.	SYNE1 EXOC4	7.66e-04	17	84	2	17903302
Pubmed	The DNA sequence and comparative analysis of human chromosome 5.	ZNF131 SPZ1 RIMOC1	8.10e-04	75	84	3	15372022
Pubmed	A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.	PTPRK ARMCX2 HTT	8.10e-04	75	84	3	15383276
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	CSE1L IARS1 LARS1 RRM1	9.50e-04	179	84	4	36261009
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	SYNE1 MACF1	1.06e-03	20	84	2	21689717
Pubmed	The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.	CSE1L IARS1 LARS1 SYMPK XPO7	1.09e-03	320	84	5	28685749
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	GPM6B CSE1L EVA1A MPDZ MACF1	1.12e-03	322	84	5	26514267
GeneFamily	Calcium voltage-gated channel subunits	CACNA1F CACNA2D4 CACNA1I	8.14e-05	26	59	3	253
GeneFamily	Keratins, type II	KRT3 KRT84 KRT79	9.13e-05	27	59	3	609
GeneFamily	Exportins	CSE1L XPO7	2.18e-04	7	59	2	547
GeneFamily	Exocyst complex	EXOC8 EXOC4	3.71e-04	9	59	2	1055
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEA WDFY3	3.71e-04	9	59	2	1230
GeneFamily	Aminoacyl tRNA synthetases, Class I	IARS1 LARS1	1.73e-03	19	59	2	131
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS9 ADAMTS14	1.73e-03	19	59	2	50
GeneFamily	DNA polymerases	POLG REV3L	2.53e-03	23	59	2	535
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARMCX2 ARMC1	8.68e-03	43	59	2	409
Coexpression	GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP	IL15 CDC42BPA RALGPS2 PLA2G15 UBE2Q2 FBXL5	1.88e-05	171	84	6	M6746
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	VPS13D SYNE1 SESN3 MACF1 NEK9 HMG20A	2.85e-05	184	84	6	M9005
Coexpression	GSE3982_MAC_VS_BCELL_DN	HAUS7 PTPRK SYNE1 POLG DEF6 RALGPS2	4.17e-05	197	84	6	M5495
Coexpression	GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN	IL15 ADNP2 TRAK2 REV3L HMG20A XPO7	4.41e-05	199	84	6	M8974
Coexpression	GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP	FOCAD MACF1 PLA2G15 NEK9 VPS13B XPO7	4.54e-05	200	84	6	M3271
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP	CSE1L TRAK2 KCTD18 VPS13B HMG20A XPO7	4.54e-05	200	84	6	M8497
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	VWA3A PTPRK SYNE1 MPDZ NBEA DNAH6	1.88e-06	195	84	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	VWA3A PTPRK SYNE1 MPDZ NBEA DNAH6	1.88e-06	195	84	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	VWA3A PTPRK SYNE1 MPDZ MACF1 DNAH6	1.94e-06	196	84	6	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	VWA3A PTPRK SYNE1 MPDZ MACF1 DNAH6	1.94e-06	196	84	6	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	FOCAD NBEA ZSWIM6 WDFY3 VPS13B EXOC4	2.12e-06	199	84	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL6B DROSHA RRH MPDZ NEK9	1.44e-05	163	84	5	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SYNE1 SESN3 MACF1 ARIH1 CCDC144A	1.81e-05	171	84	5	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWA3A IL15 KCNT2 SYNE1 ITGA3	2.85e-05	188	84	5	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VWA3A IL15 KCNT2 SYNE1 ITGA3	2.85e-05	188	84	5	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	VWA3A PTPRK MPDZ ITGA3 DNAH6	3.16e-05	192	84	5	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRK MACF1 ZSWIM6 VPS13B EXOC4	3.16e-05	192	84	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 SESN3 MACF1 USP9Y VPS13B	3.23e-05	193	84	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	PTPRK ZSWIM6 WDFY3 VPS13B EXOC4	3.65e-05	198	84	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GPM6B SYNE1 RALGPS2 MACF1 REV3L	3.74e-05	199	84	5	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GPM6B SYNE1 RALGPS2 MACF1 REV3L	3.83e-05	200	84	5	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
Computational	Neighborhood of RAB10	LARS1 SESN3 MACF1 NEK9 VPS13B FBXL5	1.55e-04	176	50	6	GCM_RAB10
Drug	Methyldopate hydrochloride [2508-79-4]; Up 200; 14.6uM; MCF7; HT_HG-U133A	GPM6B ADAMTS9 DEF6 CACNA1I WDFY3 PLA2G15 SYMPK	8.30e-06	199	83	7	4986_UP
Drug	AC1L2O7O	RRM2B RRM1	1.31e-05	2	83	2	CID000075180
Drug	tris(tetrabutylammonium) hydrogen pyrophosphate	RRM2B RRM1	1.31e-05	2	83	2	CID011115639
Drug	2-amino-1-hydroxyguanidine	RRM2B RRM1	1.31e-05	2	83	2	CID005464082
Drug	NSC636979	IARS1 LARS1	1.31e-05	2	83	2	CID000367344
Drug	SureCN843110	RRM2B RRM1	1.31e-05	2	83	2	CID014570995
Drug	v 1394	RRM2B RRM1	1.31e-05	2	83	2	CID000101484
Drug	AC1L2J0W	RRM2B POLG REV3L RRM1	1.65e-05	42	83	4	CID000072957
Drug	Adenosine phosphonoacetic acid	RRM2B RRM1	3.93e-05	3	83	2	CID000448505
Drug	AC1N8OVF	RRM2B RRM1	3.93e-05	3	83	2	CID004347182
Drug	2'-deoxytoyocamycin	RRM2B RRM1	3.93e-05	3	83	2	CID000204132
Drug	2'-chloro-2'-dudp	RRM2B RRM1	3.93e-05	3	83	2	CID003082518
Drug	1-amino-3-hydroxyguanidine	RRM2B RRM1	3.93e-05	3	83	2	CID009571038
Drug	Bild 1351	RRM2B RRM1	3.93e-05	3	83	2	CID005478827
Drug	beta-dimethylaminopropiophenone	RRM2B RRM1	3.93e-05	3	83	2	CID000077042
Drug	3,4-dihydroxybenzaldoxime	RRM2B RRM1	3.93e-05	3	83	2	CID005388593
Drug	hydroxyguanidine sulfate	RRM2B RRM1	3.93e-05	3	83	2	CID000080667
Drug	2D ABR	RRM2B RRM1	3.93e-05	3	83	2	CID000125209
Drug	NSC-137029	RRM2B RRM1	3.93e-05	3	83	2	CID000421633
Drug	Bild 1357	RRM2B RRM1	3.93e-05	3	83	2	CID000515298
Drug	2'-azido-2'-deoxycytidine 5'-diphosphate	RRM2B RRM1	3.93e-05	3	83	2	CID000170963
Drug	AC1LAKEY	RRM2B RRM1	3.93e-05	3	83	2	CID000515340
Drug	Val-Val-Asn-Asp-Leu	RRM2B RRM1	3.93e-05	3	83	2	CID000515343
Drug	6-aminothymine	RRM2B RRM1	3.93e-05	3	83	2	CID000065245
Drug	dial-CDP	RRM2B RRM1	3.93e-05	3	83	2	CID005487791
Drug	cyclo(Sar-Sar	RRM2B RRM1	3.93e-05	3	83	2	CID000078761
Drug	F-ara-ATP	RRM2B POLG RRM1	6.84e-05	22	83	3	CID000126498
Drug	3'-deoxythymidine	RRM2B POLG REV3L RRM1	7.31e-05	61	83	4	CID000005280
Drug	Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A	ANOS1 CDC42BPA SYNE1 DEF6 MAPK7 PADI2	7.54e-05	193	83	6	7059_DN
Drug	2-formylpyridine thiosemicarbazonato copper(II	RRM2B RRM1	7.84e-05	4	83	2	CID009576822
Drug	4-nitro-benzohydrazide	RRM2B RRM1	7.84e-05	4	83	2	CID003693744
Drug	AC1O7EGN	RRM2B RRM1	7.84e-05	4	83	2	CID006446439
Drug	BPYTA	RRM2B RRM1	7.84e-05	4	83	2	CID003034633
Drug	2-formylpyridine thiosemicarbazone	RRM2B RRM1	7.84e-05	4	83	2	CID001638752
Drug	p-propoxyphenol	RRM2B RRM1	7.84e-05	4	83	2	CID000029352
Drug	Dacisteine	RRM2B RRM1	7.84e-05	4	83	2	CID000065690
Drug	2'-azido-2'-deoxyuridine	RRM2B RRM1	7.84e-05	4	83	2	CID000168629
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; PC3; HT_HG-U133A	GPM6B ANOS1 CDC42BPA MAPK7 ARMCX2 HTT	7.98e-05	195	83	6	6698_DN
Drug	Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; MCF7; HT_HG-U133A	GPM6B VPS13D CDC42BPA MAPK7 VPS13B SYMPK	8.21e-05	196	83	6	5461_DN
Drug	0297417-0002B [362658-29-5]; Down 200; 10uM; MCF7; HT_HG-U133A	CDC42BPA CCNE2 POLG MPDZ RRM1 XPO7	8.21e-05	196	83	6	6902_DN
Drug	Dimethadione [695-53-4]; Down 200; 31uM; HL60; HT_HG-U133A	GPM6B VPS13D CSE1L POLG PLA2G15 HTT	8.21e-05	196	83	6	3029_DN
Drug	PNU-0293363 [326823-19-2]; Up 200; 10uM; PC3; HT_HG-U133A	GPM6B CCNE2 DEF6 MPDZ MAPK7 RRM1	8.21e-05	196	83	6	6568_UP
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A	VPS13D SYNE1 DEF6 WDFY3 MAPK7 NEK9	8.44e-05	197	83	6	4767_DN
Drug	Fluorocurarine chloride [22273-09-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	FOCAD VPS13D WDFY3 MAPK7 NEK9 SYMPK	8.68e-05	198	83	6	6083_DN
Drug	ara-C triphosphate	RRM2B POLG RRM1	8.95e-05	24	83	3	CID000455319
Drug	globomycin	IARS1 LARS1 RRM1	1.14e-04	26	83	3	CID000115071
Drug	dFdCTP	RRM2B POLG RRM1	1.28e-04	27	83	3	CID000130659
Drug	motropin	RRM2B RRM1	1.30e-04	5	83	2	CID000064657
Drug	AC1NQVLK	RRM2B RRM1	1.30e-04	5	83	2	CID002732427
Drug	8-in	ARIH1 HTT	1.30e-04	5	83	2	CID000003711
Drug	A1110U	RRM2B RRM1	1.30e-04	5	83	2	CID003006964
Drug	2-methylene-3-furanone	RRM2B RRM1	1.30e-04	5	83	2	CID000124504
Drug	348U87	RRM2B RRM1	1.30e-04	5	83	2	CID003006985
Drug	2-hydroxy-1-naphthylaldehyde benzoyl hydrazone	RRM2B RRM1	1.30e-04	5	83	2	CID005384003
Drug	p-butoxyphenol	RRM2B RRM1	1.30e-04	5	83	2	CID000031233
Drug	mdGuo	RRM2B RRM1	1.30e-04	5	83	2	CID000126596
Drug	bruceine	RRM2B RRM1	1.30e-04	5	83	2	CID000122785
Drug	acetylpyrazine	RRM2B RRM1	1.30e-04	5	83	2	CID000030914
Drug	MdAdo	RRM2B RRM1	1.30e-04	5	83	2	CID000175972
Drug	N-hydroxy-N'-methylurea	RRM2B RRM1	1.30e-04	5	83	2	CID000096412
Drug	Citrusinine-I	RRM2B RRM1	1.30e-04	5	83	2	CID005487772
Drug	AC1Q6S3R	RRM2B POLG REV3L RRM1	1.32e-04	71	83	4	CID000000625
Drug	ganciclovir	AP1G1 RRM2B POLG REV3L RRM1	1.62e-04	140	83	5	CID000003454
Drug	dideoxyinosine	CACNA2D4 RRM2B POLG RRM1	1.64e-04	75	83	4	CID000003043
Drug	AC1L1GVK	RRM2B POLG REV3L RRM1	1.73e-04	76	83	4	CID000003860
Drug	AC1Q6S3S	HAUS7 RRM2B POLG REV3L RRM1	1.73e-04	142	83	5	CID000001151
Drug	3-acetylisoquinoline	RRM2B RRM1	1.95e-04	6	83	2	CID000124656
Drug	VF 122	RRM2B RRM1	1.95e-04	6	83	2	CID000100590
Drug	MK-410	RRM2B RRM1	1.95e-04	6	83	2	CID006451644
Drug	Tdho	RRM2B RRM1	1.95e-04	6	83	2	CID003037009
Drug	2'-chloro-2'-deoxyadenosine	RRM2B RRM1	1.95e-04	6	83	2	CID000100327
Drug	9-aminoacridine	SYNE1 POLG REV3L ARMC1	2.00e-04	79	83	4	CID000007019
Drug	1q1m	SYNE1 MC3R RRM1	2.15e-04	32	83	3	CID000447994
Drug	CNS 1145	CACNA1F CACNA2D4 CACNA1I	2.36e-04	33	83	3	CID000190902
Drug	IHC-64	CACNA1F CACNA2D4 CACNA1I	2.36e-04	33	83	3	CID000162753
Drug	TRIBIZ	GPM6B CSE1L RRM1	2.36e-04	33	83	3	CID000449279
Drug	monomethyl azelate	RRM2B RRM1	2.72e-04	7	83	2	CID000075009
Drug	maltolate	IL15 RRM2B RRM1	2.81e-04	35	83	3	CID000092427
Drug	benzohydroxamic acid	ANOS1 RRM2B RRM1	2.81e-04	35	83	3	CID000010313
Drug	S)-HPMPA	RRM2B POLG RRM1	3.06e-04	36	83	3	CID000072253
Drug	AC1Q6S3Y	RRM2B POLG REV3L RRM1	3.31e-04	90	83	4	CID000000646
Drug	corundum	CSE1L ARIH1 HTT	3.59e-04	38	83	3	CID000014769
Drug	GC Q	RRM2B RRM1	3.62e-04	8	83	2	CID006420157
Drug	parabactin	RRM2B RRM1	3.62e-04	8	83	2	CID005487017
Drug	B Hm	RRM2B RRM1	3.62e-04	8	83	2	CID000100038
Drug	hydroxamate 11	RRM2B RRM1	3.62e-04	8	83	2	CID010001582
Drug	AC1MHU3O	RRM2B RRM1	3.62e-04	8	83	2	CID003032423
Drug	N3UDP	RRM2B RRM1	3.62e-04	8	83	2	CID000169817
Disease	MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY SYNDROME	RRM2B POLG	2.34e-05	3	83	2	C0872218
Disease	Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1	RRM2B POLG	7.77e-05	5	83	2	C1834846
Disease	cerebellar ataxia (is_implicated_in)	SYNE1 POLG	7.77e-05	5	83	2	DOID:0050753 (is_implicated_in)
Disease	Seizures	RRM2B POLG MPDZ MACF1 NBEA	3.82e-04	218	83	5	C0036572
Disease	Night blindness, congenital stationary	CACNA1F CACNA2D4	1.03e-03	17	83	2	C0339535
Disease	blood pressure	SYNE1 EXOC4	1.74e-03	22	83	2	EFO_0004325

Protein segments in the cluster

Peptide	Gene	Start	Entry
YTQLLEITLHLQQAM	ACCSL	26	Q4AC99
SIVVVDHLSYNTLMA	BHLHB9	521	Q6PI77
TILYQFLMNEVVHTS	ARL5B	31	Q96KC2
YTIDMHSQLELTASL	CATSPERD	401	Q86XM0
NIQTHTNYLAMLEEV	CCNE2	356	O96020
LLASEIYDILQSSNM	ARMC1	101	Q9NVT9
TLEMELSNSHLVQGY	AMER1	901	Q5JTC6
MTITNDYQHLLVNSI	ARMCX2	496	Q7L311
TLMNIVDEIYHDESL	ADAMTS14	286	Q8WXS8
SQDALMYHILTSDIH	ADNP2	226	Q6IQ32
EHIEMLANATTLAYL	PLA2G15	391	Q8NCC3
HVEMALLSNILAAYS	EVA1A	11	Q9H8M9
SQTEHNIVATYLIMA	RRH	21	O14718
SPEQHNLSLYSMELV	KIAA1549	66	Q9HCM3
YEVLTAEQILQHMVE	ARIH1	101	Q9Y4X5
LIQLITNSVEMHAYT	AP1G1	441	O43747
LLNTVALAMQHYEQT	CACNA1F	1201	O60840
MTHENYIILQDLSFS	ANOS1	481	P23352
ELMLSLHEYTQAIDL	MAPK7	231	Q13164
LYMEEIQLLQSHISE	KRT84	301	Q9NSB2
LEQQLTSDIIMSDSY	GPR61	426	Q9BZJ8
NHFMDNTTLLIELEY	NEK9	116	Q8TD19
DTIDSYMNRLHSIIL	HMG20A	311	Q9NP66
EDLIQSMHIDATLYT	IL15	61	P40933
RTLYDAELSQMQSHI	KRT3	336	P12035
QLYEMELSQVQTHVS	KRT79	281	Q5XKE5
VDYTLQTSLSMVNHR	ITGA3	756	P26006
VQSSAVDYLHLMLVA	POLG	1101	P54098
LNLTELALTMNHVYS	NCKAP1L	681	P55160
DEMNDHQSTLSYILI	KCNT2	1071	Q6UVM3
VSIHVSLLEYMAQDI	PADI2	266	Q9Y2J8
ESEMYQLSHLLTEQK	EXOC8	81	Q8IYI6
DHALLSEVIQLMQYV	GPM6B	76	Q13491
ENLLFQLMTHSYINV	MACF1	1966	Q9UPN3
NASLVLYLQTSETHM	PRTG	766	Q2VWP7
LVYSAHDTTLVALQM	ACP2	281	P11117
HDTTLVALQMALDVY	ACP2	286	P11117
HLANEMETYSLRSNI	KCTD18	106	Q6PI47
TVQDLLNLMHDLSAY	EXOC4	586	Q96A65
ENLQHYILTLMSIVA	ADAMTS9	311	Q9P2N4
YLIENTMHILTVNAV	DNAH6	446	Q9C0G6
DQSSVYLKLLMHETQ	HTT	956	P42858
VLAAATYLQMEHVVQ	BCL6B	111	Q8N143
ISTLADTQENVMEYL	CACNA2D4	456	Q7Z3S7
IICLNVVTMSLEHYN	CACNA1I	1496	Q9P0X4
SHSVYENFMLLIEQL	CCDC144B	611	Q3MJ40
TSYSQLLQVVMAVAD	HAUS7	306	Q99871
TLSMAIHEVYQELIQ	DEF6	201	Q9H4E7
NALETIMIAIVHSDY	MC3R	91	P41968
IYNVHSDNKLSEMLS	FBXL5	76	Q9UKA1
SHSVYENFMLLIEQL	CCDC144A	611	A2RUR9
MVLDTLLVIVDSHYQ	FOCAD	1001	Q5VW36
IIYLNSIQELEIHNM	PRAMEF13	201	Q5VWM6
DLLQHINLMKTSDSY	PTPRK	871	Q15262
LYELNNLHALMAVVS	RALGPS2	131	Q86X27
DSIMQLVATEYLFIH	DROSHA	1151	Q9NRR4
MTEHYVTQLELQDLQ	SYNE1	3456	Q8NF91
LMNESSELHTQLAKY	SYNE1	4591	Q8NF91
SNLLELYTQAILDMT	RIMOC1	61	A6NDU8
VNEVLIHSSQYLMEV	LARS1	891	Q9P2J5
MENIVYLTNSLELEH	LARS1	1021	Q9P2J5
DELQSILNYLLTMHE	NBEA	701	Q8NFP9
LNIHLTAYDMTLAES	MRPL48	91	Q96GC5
VSVQDKDTLSIHYLM	IARS1	791	P41252
EEMYRLQQLSVSATH	KIAA0753	661	Q2KHM9
YLAEMVIAIDSVHQL	CDC42BPA	181	Q5VT25
FQILIENVHSEMYSL	RRM2B	126	Q7LG56
TKTYNDIDMVTHLLA	TRAK2	106	O60296
YLSTNLVSHIEEMLQ	GTF2H1	516	P32780
AYSIESVIMQINATL	UBE2Q2	316	Q8WVN8
MELSDANLQTLTEYL	CSE1L	1	P55060
QTYILDSVMDHLLAA	WDFY3	2006	Q8IZQ1
LHMSLEELYTQNLLQ	MPDZ	896	O75970
MEEAILLNQTSLVTY	OR4E1	1	P0C645
MATLLDHDLSETIYQ	REV3L	1891	O60673
AIIAYLMHSNEQTLQ	STYXL1	256	Q9Y6J8
LASLALNMYVTSEHT	RRM1	446	P23921
TQVMSLHTQYLESFL	SESN3	76	P58005
HALVTLVAENLATYM	USP9Y	611	O00507
MSEVIQAYETLHANL	SYMPK	271	Q92797
TLAMTHLNLSYNQDT	ZSWIM6	1051	Q9HCJ5
LDSSQRHLYSNVMLE	ZNF570	31	Q96NI8
MYAEQLVHVVSSLTQ	VPS13B	706	Q7Z7G8
YSLLEVLTQDHMNFI	XPO7	891	Q9UIA9
SHDTYSLQLMAALLE	SPZ1	311	Q9BXG8
SHMSELPEQVQVSYL	ZNF131	511	P52739
SSDIQLYHSETLELM	PPIP5K2	686	O43314
LDISATNSMYIIHIQ	VWA3A	516	A6NCI4
YTQLATSHMLELSIQ	VPS13D	3861	Q5THJ4