Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

3.04e-0843111615GO:0004984
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 PROKR1 HCAR3 OR4M2 TAS1R2 OR2D3 OR4C13 OR4X2 TACR1

3.48e-0888411621GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4C45 OR4M1 OR2B3 ABCA7 OR4M2B OR5AL1 PROKR1 HCAR3 OR4M2 INTS6 PTPRK TAS1R2 OR2D3 OR4C13 OR4X2 TACR1 ALK

1.93e-07135311625GO:0004888
GeneOntologyMolecularFunctionnicotinic acid receptor activity

HCAR2 HCAR3

3.35e-0521162GO:0070553
GeneOntologyMolecularFunctionprotein serine kinase activity

TRPM7 NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40

5.15e-0536311610GO:0106310
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXO1 SOX9 SOX10 TBX3 ERG RUNX2 HOXC13 ZBED4 BARHL1 BARHL2 NFKB2 PAX9

1.02e-0456011612GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXO1 SOX9 SOX10 TBX3 ERG RUNX2 HOXC13 ZBED4 BARHL1 BARHL2 NFKB2 PAX9

1.13e-0456611612GO:0001216
GeneOntologyMolecularFunctionprotein kinase activity

TRPM7 NEK10 PDK4 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40 ALK

1.94e-0460011612GO:0004672
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TRPM7 NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40

2.77e-0444611610GO:0004674
GeneOntologyMolecularFunctionphosphodiesterase I activity

ENPP2 ENPP3

3.31e-0451162GO:0004528
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACB

6.89e-0471162GO:0004691
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TRPM7 NEK10 PDK4 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40 ALK

8.63e-0470911612GO:0016773
GeneOntologyMolecularFunctionodorant binding

OR8D1 OR8D2 OR5M1 OR5AS1 OR5AL1

8.78e-041271165GO:0005549
GeneOntologyMolecularFunctioncyclic nucleotide-dependent protein kinase activity

PRKACA PRKACB

1.17e-0391162GO:0004690
GeneOntologyMolecularFunctionAMP-activated protein kinase activity

PRKACA PRKACB

1.46e-03101162GO:0004679
GeneOntologyMolecularFunctionkinase activity

TRPM7 NEK10 PDK4 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40 ALK

1.63e-0376411612GO:0016301
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

FOXO1 SOX9 SOX10 TBX3 IRX5 ERG NFKBIZ IRX1 RUNX2 IRX4 HOXC13 ZBED4 BARHL1 BARHL2 NFKB2 ZFHX3 NR3C2 PAX9

1.86e-03145911618GO:0000977
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 TAS1R2 OR2D3 OR4C13 OR4X2

8.18e-0948511216GO:0050907
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

1.26e-0843211215GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 TAS1R2 OR2D3 OR4C13 OR4X2

2.41e-0852411216GO:0009593
GeneOntologyBiologicalProcesssensory perception of smell

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

3.35e-0846511215GO:0007608
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 TAS1R2 OR2D3 OR4C13 OR4X2

4.37e-0854711216GO:0007606
GeneOntologyBiologicalProcessdetection of stimulus

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 CDHR2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 TAS1R2 OR2D3 OR4C13 OR4X2 TACR1

6.58e-0872211218GO:0051606
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 PROKR1 HCAR3 OR4M2 PRKACA PRKACB TAS1R2 OR2D3 OR4C13 NR3C2 OR4X2 TACR1 ALK

9.09e-08139511225GO:0007186
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 TAS1R2 OR2D3 OR4C13 OR4X2

1.02e-0758211216GO:0050906
GeneOntologyBiologicalProcesssensory perception

OR2A14 OR8D1 IRX5 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2B OR5AL1 OR4M2 BARHL1 TAS1R2 OR2D3 OR4C13 OR4X2

1.83e-05107211218GO:0007600
GeneOntologyBiologicalProcessnegative regulation of lipid catabolic process

HCAR2 HCAR1 HCAR3 ALK

3.37e-05341124GO:0050995
GeneOntologyBiologicalProcesshigh-density lipoprotein particle assembly

ABCA7 PRKACA PRKACB

4.28e-05131123GO:0034380
GeneOntologyBiologicalProcesscilium movement

NEK10 ASH1L OR4M1 GARIN2 CFAP65 OR4M2 TACR1 DNAH8

9.03e-052611128GO:0003341
GeneOntologyBiologicalProcesspositive regulation of cilium-dependent cell motility

OR4M1 OR4M2 TACR1

1.20e-04181123GO:2000155
GeneOntologyBiologicalProcesspositive regulation of flagellated sperm motility

OR4M1 OR4M2 TACR1

1.20e-04181123GO:1902093
GeneOntologyBiologicalProcesspositive regulation of cilium movement

OR4M1 OR4M2 TACR1

1.42e-04191123GO:0003353
GeneOntologyBiologicalProcesscilium movement involved in cell motility

ASH1L OR4M1 GARIN2 CFAP65 OR4M2 TACR1 DNAH8

1.51e-042101127GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

ASH1L OR4M1 GARIN2 CFAP65 OR4M2 TACR1 DNAH8

1.74e-042151127GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

ASH1L OR4M1 GARIN2 CFAP65 OR4M2 TACR1 DNAH8

1.74e-042151127GO:0001539
GeneOntologyBiologicalProcesspositive regulation of adiponectin secretion

HCAR2 HCAR3

1.74e-0441122GO:0070165
DomainGPCR_Rhodpsn_7TM

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4M1 OR2B3 PROKR1 HCAR3 OR4M2 OR2D3 OR4C13 OR4X2 TACR1

4.94e-0767011217IPR017452
Domain7tm_1

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4M1 OR2B3 PROKR1 HCAR3 OR4M2 OR2D3 OR4C13 OR4X2 TACR1

5.70e-0767711217PF00001
DomainG_PROTEIN_RECEP_F1_1

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4M1 OR2B3 PROKR1 HCAR3 OR4M2 OR2D3 OR4C13 OR4X2 TACR1

6.71e-0768511217PS00237
DomainG_PROTEIN_RECEP_F1_2

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4M1 OR2B3 PROKR1 HCAR3 OR4M2 OR2D3 OR4C13 OR4X2 TACR1

7.57e-0769111217PS50262
DomainGPCR_Rhodpsn

OR2A14 HCAR2 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 HCAR1 OR4M1 OR2B3 PROKR1 HCAR3 OR4M2 OR2D3 OR4C13 OR4X2 TACR1

7.72e-0769211217IPR000276
DomainIRO

IRX5 IRX1 IRX4

4.14e-0661123SM00548
DomainIroquois_homeo

IRX5 IRX1 IRX4

4.14e-0661123IPR003893
DomainOlfact_rcpt

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4M1 OR2B3 OR4M2 OR2D3 OR4C13 OR4X2

4.24e-0639311212IPR000725
DomainE-NPP

ENPP6 ENPP2 ENPP3

7.22e-0671123IPR024873
DomainPhosphodiest

ENPP6 ENPP2 ENPP3

2.44e-05101123PF01663
DomainPhosphodiest/P_Trfase

ENPP6 ENPP2 ENPP3

2.44e-05101123IPR002591
DomainHCAR2/3_rcpt

HCAR2 HCAR3

3.56e-0521122IPR028017
DomainSox_N

SOX9 SOX10

1.07e-0431122IPR022151
DomainSox_N

SOX9 SOX10

1.07e-0431122PF12444
DomainDUF2075

SLFN13 SLFN11

1.07e-0431122IPR018647
DomainDUF2075

SLFN13 SLFN11

1.07e-0431122PF09848
DomainHomeobox_CS

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3

1.30e-041861127IPR017970
DomainHomeobox_KN

IRX5 IRX1 IRX4

1.34e-04171123PF05920
DomainHomeobox_KN_domain

IRX5 IRX1 IRX4

1.34e-04171123IPR008422
DomainS_TKc

NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40

3.13e-043591129SM00220
DomainKinase-like_dom

TRPM7 NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40 ALK

4.14e-0454211211IPR011009
DomainPROTEIN_KINASE_ATP

NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40 ALK

4.41e-0445911210PS00107
DomainPkinase

NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40

4.82e-043811129PF00069
DomainNUC

ENPP2 ENPP3

5.26e-0461122SM00477
DomainEndonuclease_NS

ENPP2 ENPP3

5.26e-0461122SM00892
DomainDNA/RNA_non-sp_Endonuclease

ENPP2 ENPP3

5.26e-0461122IPR001604
Domain-

ENPP2 ENPP3

5.26e-04611223.40.570.10
DomainEndonuclease_NS

ENPP2 ENPP3

5.26e-0461122PF01223
DomainExtracellular_endonuc_su_A

ENPP2 ENPP3

5.26e-0461122IPR020821
DomainHomeobox

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3

5.26e-042341127PF00046
DomainHOMEOBOX_1

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3

5.54e-042361127PS00027
DomainHOX

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3

5.68e-042371127SM00389
DomainHOMEOBOX_2

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3

5.97e-042391127PS50071
DomainHomeobox_dom

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3

5.97e-042391127IPR001356
DomainProt_kinase_dom

NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40 ALK

7.20e-0448911210IPR000719
DomainAlbA_2

SLFN13 SLFN11

7.34e-0471122PF04326
DomainSchlafen

SLFN13 SLFN11

7.34e-0471122IPR029684
DomainSchlafen_AAA_dom

SLFN13 SLFN11

7.34e-0471122IPR007421
DomainPROTEIN_KINASE_DOM

NEK10 NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40 ALK

7.66e-0449311210PS50011
DomainAlkaline_phosphatase_core

ENPP6 ENPP2 ENPP3

8.35e-04311123IPR017850
DomainAlkaline_Pase-like_a/b/a

ENPP6 ENPP2 ENPP3

8.35e-04311123IPR017849
Domain-

ENPP6 ENPP2 ENPP3

8.35e-043111233.40.720.10
DomainHomeodomain-like

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3 PAX9

8.78e-043321128IPR009057
DomainSomatomedin_B

ENPP2 ENPP3

9.75e-0481122PF01033
DomainSO

ENPP2 ENPP3

1.25e-0391122SM00201
DomainSer/Thr_kinase_AS

NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40

1.40e-033571128IPR008271
DomainPROTEIN_KINASE_ST

NEK4 NEK2 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 STK40

1.52e-033621128PS00108
DomainSomatomedin_B_dom

ENPP2 ENPP3

1.55e-03101122IPR001212
DomainSMB_1

ENPP2 ENPP3

1.55e-03101122PS00524
DomainSMB_2

ENPP2 ENPP3

1.55e-03101122PS50958
Domain-

IRX5 IRX1 IRX4 HOXC13 BARHL1 BARHL2 ZFHX3

1.59e-0328311271.10.10.60
DomainProtein_kinase_ATP_BS

NEK10 NEK4 CSNK1A1L MAPKAPK3 PRKACA PRKACB RPS6KA6 ALK

2.03e-033791128IPR017441
DomainPept_M10A_Zn_BS

MMP8 MMP13

3.56e-03151122IPR021158
Domainp53-like_TF_DNA-bd

TBX3 RUNX2 NFKB2

3.95e-03531123IPR008967
DomainPost-SET_dom

ASH1L KMT2A

4.05e-03161122IPR003616
DomainPostSET

ASH1L KMT2A

4.05e-03161122SM00508
DomainMAM_1

PTPRK ALK

4.05e-03161122PS00740
DomainPOST_SET

ASH1L KMT2A

4.05e-03161122PS50868
DomainHemopexin_CS

MMP8 MMP13

4.57e-03171122IPR018486
DomainAGC-kinase_C

PRKACA PRKACB RPS6KA6

4.62e-03561123IPR000961
DomainAGC_KINASE_CTER

PRKACA PRKACB RPS6KA6

4.62e-03561123PS51285
DomainS_TK_X

PRKACA PRKACB RPS6KA6

4.62e-03561123SM00133
DomainMAM

PTPRK ALK

5.12e-03181122PF00629
DomainMAM_dom

PTPRK ALK

5.12e-03181122IPR000998
DomainMAM_2

PTPRK ALK

5.12e-03181122PS50060
DomainPept_M10A_stromelysin-type

MMP8 MMP13

5.12e-03181122IPR016293
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR4M2 PRKACA PRKACB OR2D3 OR4C13 OR4X2

2.96e-083899215M14091
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

4.86e-074179214M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR2B3 OR5AL1 OR4M2 TAS1R2 OR2D3 OR4C13 OR4X2

1.44e-056369215M41834
PathwayWP_IL18_SIGNALING

HCAR2 TRPM7 NFKBIZ RUNX2 NFKB2 TACR1 STK40 MMP8 MMP13

7.17e-05273929M39818
PathwayWP_DOPAMINE_METABOLISM

DDC PRKACA PRKACB

7.34e-0513923M39622
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

PRKACA PRKACB RPS6KA6 LRRC7

7.62e-0535924MM15109
PathwayKEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES

ST8SIA1 GLB1 SLC33A1

1.16e-0415923M8535
PathwayREACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS

PRKACA PRKACB RPS6KA6

1.16e-0415923MM15103
PathwayREACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS

PRKACA PRKACB

4.16e-045922M26988
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

1.64e-103401181311875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

1.64e-103401181311802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

1.83e-103431181332295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4C45 OR4M1 OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

2.03e-103461181314611657
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXO1 SOX9 SOX10 TBX3 IRX5 ERG ASH1L IRX1 RUNX2 IRX4 HOXC13 ZBED4 BARHL1 BARHL2 NFKB2 KMT2A ZFHX3 NR3C2 PAX9

2.50e-109081181919274049
Pubmed

International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B).

HCAR2 HCAR1 HCAR3

3.81e-083118321454438
Pubmed

Effects of high fat diet on GPR109A and GPR81 gene expression.

HCAR2 HCAR1 HCAR3

3.81e-083118322842580
Pubmed

Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases.

HCAR2 HCAR1 HCAR3

3.81e-083118334852802
Pubmed

Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification.

SOX9 RUNX2 PRKACA PRKACB

4.08e-0811118420534695
Pubmed

The human olfactory receptor gene family.

OR2A14 OR8D1 OR8D2 OR5M1 OR2B2 OR5AS1 OR4M1 OR2B3 OR5AL1 OR4M2 OR2D3 OR4C13 OR4X2

4.25e-085411181314983052
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

SOX9 SOX10 TBX3 IRX5 ERG IRX1 RUNX2 HOXC13 BARHL1 BARHL2 NFKB2 NR3C2 PAX9

4.54e-085441181328473536
Pubmed

Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81).

HCAR2 HCAR1 HCAR3

1.52e-074118319633298
Pubmed

Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes.

SOX9 RUNX2 MMP13

1.52e-074118320196777
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

FOXO1 SOX9 SOX10 IRX5 ERG IRX4 BARHL1 ZFHX3 NR3C2

3.08e-07263118920932939
Pubmed

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.

SOX9 TBX3 IRX5 IRX1 RUNX2 BARHL1 BARHL2 PAX9

3.12e-07191118824146773
Pubmed

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.

HCAR2 HCAR1 HCAR3

3.79e-075118319047060
Pubmed

Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice.

SOX9 RUNX2 PAX9 MMP13

4.69e-0719118434732852
Pubmed

Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos.

IRX5 IRX1 IRX4

7.56e-076118320408909
Pubmed

Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development.

IRX5 IRX1 IRX4

7.56e-076118311042145
Pubmed

Iroquois homeobox 3 regulates odontoblast proliferation and differentiation mediated by Wnt5a expression.

IRX5 IRX1 IRX4

7.56e-076118336773339
Pubmed

Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast.

IRX5 IRX1 IRX4

7.56e-076118310370142
Pubmed

The prepattern transcription factor Irx3 directs nephron segment identity.

IRX5 IRX1 IRX4

1.32e-067118317875669
Pubmed

Bmp2 and Notch cooperate to pattern the embryonic endocardium.

SOX9 TBX3 IRX5 IRX4

1.78e-0626118429853617
Pubmed

Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol.

IRX5 IRX1 IRX4

2.11e-068118311118473
Pubmed

The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.

IRX5 IRX1 IRX4

3.15e-069118314585979
Pubmed

Gene and cluster-specific expression of the Iroquois family members during mouse development.

IRX5 IRX1 IRX4

3.15e-069118311520674
Pubmed

PRMT5 is necessary to form distinct cartilage identities in the knee and long bone.

SOX9 RUNX2 MMP13

4.49e-0610118331442442
Pubmed

Med23 Regulates Sox9 Expression during Craniofacial Development.

SOX9 SOX10 RUNX2

4.49e-0610118333155500
Pubmed

Trps1 is necessary for normal temporomandibular joint development.

SOX9 RUNX2 MMP13

4.49e-0610118322427063
Pubmed

Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.

TBX3 IRX1 DDC IRX4

4.77e-0633118416870172
Pubmed

SHP2 Regulates the Osteogenic Fate of Growth Plate Hypertrophic Chondrocytes.

SOX9 RUNX2 MMP13

6.16e-0611118328983104
Pubmed

JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice.

SOX9 RUNX2 MMP13

6.16e-0611118325587042
Pubmed

Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart.

IRX5 IRX1 IRX4

6.16e-0611118310926765
Pubmed

Replacing Shox2 with human SHOX leads to congenital disc degeneration of the temporomandibular joint in mice.

SOX9 RUNX2 MMP13

6.16e-0611118324248941
Pubmed

ISL1 regulates lung branching morphogenesis via Shh signaling pathway.

SOX9 TBX3 IRX1

8.19e-0612118337442233
Pubmed

The ubiquitin ligase Nedd4 regulates craniofacial development by promoting cranial neural crest cell survival and stem-cell like properties.

SOX9 SOX10 RUNX2

8.19e-0612118324080509
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR2A14 OR5M1 OR2B3 OR5AL1 OR2D3 OR4C13 OR4X2

1.04e-05219118712213199
Pubmed

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate.

SOX9 RUNX2 MMP13

1.06e-0513118337296099
Pubmed

Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.

HCAR2 HCAR3

1.14e-052118228186140
Pubmed

The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.

HCAR2 HCAR3

1.14e-052118230154797
Pubmed

Glucose regulates tissue-specific chondro-osteogenic differentiation of human cartilage endplate stem cells via O-GlcNAcylation of Sox9 and Runx2.

SOX9 RUNX2

1.14e-052118231779679
Pubmed

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

PRKACA PRKACB

1.14e-05211823023318
Pubmed

Reduced activity and cytoplasmic localization of Runx2 is observed in C3h10t1/2 cells overexpressing Tbx3.

TBX3 RUNX2

1.14e-052118221455926
Pubmed

NEK2 promotes the development of ovarian endometriosis and impairs decidualization by phosphorylating FOXO1.

FOXO1 NEK2

1.14e-052118238795132
Pubmed

The role of HCA2 (GPR109A) in regulating macrophage function.

HCAR2 HCAR3

1.14e-052118223882124
Pubmed

Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.

HCAR2 HCAR3

1.14e-052118236891315
Pubmed

Endogenous Collagenases Regulate Osteoclast Fusion.

MMP8 MMP13

1.14e-052118232370054
Pubmed

In vitro osteogenic potential of human mesenchymal stem cells is predicted by Runx2/Sox9 ratio.

SOX9 RUNX2

1.14e-052118224980654
Pubmed

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a.

HCAR2 HCAR3

1.14e-052118238007572
Pubmed

AKT-mediated phosphorylation of Sox9 induces Sox10 transcription in a murine model of HER2-positive breast cancer.

SOX9 SOX10

1.14e-052118233985544
Pubmed

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.

HCAR2 HCAR3

1.14e-052118224691444
Pubmed

Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue-specific mechanisms.

HCAR2 HCAR3

1.14e-052118231347703
Pubmed

Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation.

RUNX2 MMP13

1.14e-052118210330183
Pubmed

Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.

HCAR2 HCAR3

1.14e-052118230659164
Pubmed

Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype.

MMP8 MMP13

1.14e-052118219233360
Pubmed

Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium.

HCAR2 HCAR3

1.14e-052118219223991
Pubmed

Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.

HCAR2 HCAR3

1.14e-052118223967184
Pubmed

Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice.

HCAR2 HCAR3

1.14e-052118226371038
Pubmed

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.

HCAR2 HCAR3

1.14e-052118234653248
Pubmed

Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).

HCAR2 HCAR3

1.14e-052118219136666
Pubmed

G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.

HCAR2 HCAR3

1.14e-052118233488584
Pubmed

Lactate-induced activation of HCA2 improves survival in mice with sepsis.

HCAR2 HCAR3

1.14e-052118230951370
Pubmed

Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC-ERK1/2-AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet.

HCAR2 HCAR3

1.14e-052118231858105
Pubmed

Exploring the role of the metabolite-sensing receptor GPR109a in diabetic nephropathy.

HCAR2 HCAR3

1.14e-052118232068460
Pubmed

The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome.

HCAR2 HCAR3

1.14e-052118230657794
Pubmed

Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.

HCAR2 HCAR3

1.14e-052118234092246
Pubmed

Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.

SOX9 SOX10

1.14e-052118225629959
Pubmed

Investigation of -PRKACA/-PRKACB fusion genes in oncocytic tumors of the pancreatobiliary and other systems.

PRKACA PRKACB

1.14e-052118236152045
Pubmed

PRKACA/PRKACB Fusions in Pancreatobiliary Intraductal Oncocytic Papillary Neoplasms Including Those With Atypical Morphology: An Analysis of 22 Cases Expanding Morphologic Spectrum.

PRKACA PRKACB

1.14e-052118238841868
Pubmed

The ERG-Regulated LINC00920 Promotes Prostate Cancer Cell Survival via the 14-3-3ε-FOXO Pathway.

FOXO1 ERG

1.14e-052118232646965
Pubmed

Molecular identification of high and low affinity receptors for nicotinic acid.

HCAR2 HCAR3

1.14e-052118212522134
Pubmed

Expression of SOX9 and SOX10 in central neuroepithelial tumor.

SOX9 SOX10

1.14e-052118216791471
Pubmed

G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.

HCAR2 HCAR3

1.14e-052118230271409
Pubmed

Niacin fine-tunes energy homeostasis through canonical GPR109A signaling.

HCAR2 HCAR3

1.14e-052118230596513
Pubmed

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.

HCAR2 HCAR3

1.14e-052118235320002
Pubmed

DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes.

RUNX2 MMP13

1.14e-052118228798419
Pubmed

GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.

HCAR2 HCAR3

1.14e-052118216322797
Pubmed

Nicotinic acid receptor agonists.

HCAR2 HCAR3

1.14e-052118218983141
Pubmed

Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms.

HCAR2 HCAR3

1.14e-052118231366236
Pubmed

Molecular and behavioral effects of a null mutation in all PKA C beta isoforms.

PRKACA PRKACB

1.14e-052118212139926
Pubmed

Mammalian BarH1 confers commissural neuron identity on dorsal cells in the spinal cord.

BARHL1 BARHL2

1.14e-052118212657654
Pubmed

GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice.

HCAR2 HCAR3

1.14e-052118235489706
Pubmed

Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase.

PRKACA PRKACB

1.14e-05211822833513
Pubmed

Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis.

HCAR2 HCAR3

1.14e-052118219561068
Pubmed

Identification and characterization of Runx2 phosphorylation sites involved in matrix metalloproteinase-13 promoter activation.

RUNX2 MMP13

1.14e-052118219264160
Pubmed

The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.

HCAR2 HCAR3

1.14e-052118224371223
Pubmed

High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.

HCAR2 HCAR3

1.14e-052118221774590
Pubmed

FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression.

FOXO1 PDK4

1.14e-052118228687587
Pubmed

Tranilast stimulates endochondral ossification by upregulating SOX9 and RUNX2 promoters.

SOX9 RUNX2

1.14e-052118226777999
Pubmed

Global consequences of activation loop phosphorylation on protein kinase A.

PRKACA PRKACB

1.14e-052118219965870
Pubmed

GPR109a Regulates Phenotypic and Functional Alterations in Macrophages and the Progression of Type 1 Diabetes.

HCAR2 HCAR3

1.14e-052118236208084
Pubmed

Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1.

ESRP1 ALK

1.14e-052118227119231
Pubmed

The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells.

HCAR2 HCAR3

1.14e-052118226656756
Pubmed

Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro.

SOX9 SOX10

1.14e-052118215896776
Pubmed

Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.

HCAR2 HCAR3

1.14e-052118237597514
Pubmed

The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.

HCAR2 HCAR3

1.14e-052118233924461
Pubmed

Ketone Body 3-Hydroxybutyrate Ameliorates Atherosclerosis via Receptor Gpr109a-Mediated Calcium Influx.

HCAR2 HCAR3

1.14e-052118233977048
Pubmed

Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism.

HCAR1 HCAR3

1.14e-052118225839160
Pubmed

SOX9 determines RUNX2 transactivity by directing intracellular degradation.

SOX9 RUNX2

1.14e-052118220593410
Pubmed

PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily.

HCAR2 HCAR3

1.14e-052118211745392
GeneFamilyHydroxy-carboxylic acid receptors

HCAR2 HCAR1 HCAR3

1.23e-073913200
GeneFamilyNeuroblastoma breakpoint family

NBPF12 NBPF26 NBPF20 NBPF1

4.94e-0623914662
GeneFamilyTALE class homeoboxes and pseudogenes

IRX5 IRX1 IRX4

2.95e-0426913526
GeneFamilyOlfactory receptors, family 4

OR4C45 OR4M1 OR4M2 OR4C13 OR4X2

4.87e-04129915151
GeneFamilySchlafen family

SLFN13 SLFN11

5.18e-0479121110
GeneFamilyMitogen-activated protein kinase-activated protein kinases

MAPKAPK3 RPS6KA6

1.34e-03119121156
GeneFamilyOlfactory receptors, family 2

OR2A14 OR2B2 OR2B3 OR2D3

2.55e-03113914149
GeneFamilySRY-boxes

SOX9 SOX10

4.05e-0319912757
CoexpressionBENPORATH_SUZ12_TARGETS

SOX9 SOX10 TBX3 IRX5 ERG ST8SIA1 IRX1 PCDH17 IRX4 HOXC13 BARHL1 BARHL2 RPS6KA6 ZFHX3 TACR1 SLFN11 PAX9

2.16e-06103511317M9898
CoexpressionWANG_MLL_TARGETS

HCAR2 PDK4 ENPP3 PARP14 HCAR3 HOXC13 RPS6KA6 PAX9 MMP13

7.39e-063061139MM1076
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

STARD13 TBX3 ITGA1 RUNX2 CPED1 CEP120 ZFHX3 LRRC7

4.24e-081931168e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERG ENPP2 ST8SIA1 CPED1 CEP120 KCNT2 ZFHX3

6.09e-07187116713731298bc562ec29582f5da1b4c97261284f6f1
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TBX3 ERG ITGA1 CPED1 CEP120 ZFHX3 LRRC7

6.54e-071891167b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TBX3 ERG ITGA1 CPED1 CEP120 ZFHX3 LRRC7

6.54e-071891167f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TBX3 ERG HCAR1 NBPF26 NFKBIZ NEK4

3.68e-061581166de65af8d3b8514b17978155f31975e2347b75251
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

TBX3 ERG ENPP2 PCDH17 KIAA1549L TACR1

5.42e-061691166605cc2638271803cf1d972ab3fa8f13f89666376
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

TBX3 ERG ENPP2 PCDH17 KIAA1549L TACR1

5.42e-061691166337be3bf485b54afad86e256cb0c4c1d0c2a9a2a
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 TBX3 GCNT3 NEK10 PDK4 RUNX2

7.77e-06180116649829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 ERG ENPP2 OR5AS1 PCDH17 TACR1

8.28e-0618211663cbeaf7904a76c32137a00abb20e302d3d3c8bb8
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

STARD13 TBX3 ERG ITGA1 PCDH17 SLC14A1

8.81e-0618411665f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 SOX9 MYOM1 PDK4 SLC14A1 DISP3

8.81e-06184116622c18964818fc9c8f18051f836d718937b0d8d12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ERG ENPP2 ST8SIA1 CPED1 CEP120 ZFHX3

9.09e-0618511669f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

SORBS2 MYOM1 TRPM7 NEK10 SLC7A6 CPED1

9.96e-0618811660758b474457efa36488e0195f7357100f4b6a090
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Trm_Th1/Th17|lymph-node_spleen / Manually curated celltypes from each tissue

NFKBIZ ITGA1 RUNX2 INTS6 NFKB2 TAS1R2

9.96e-061881166a20521198c6db17589535fb439533329582c9dd2
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_early|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CELF4 IRX5 ESRP1 IRX1 DDC NEK2

1.03e-051891166a6c62b456982067ad4d224a2efa3919969000693
ToppCell18-Airway-Epithelial-Submucosal_gland|Airway / Age, Tissue, Lineage and Cell class

SOX9 SORBS2 GCNT3 ENPP3 NFKBIZ PAX9

1.03e-051891166c1ea2dc44cf5340378e56e0ffc2e6f64e6c95a58
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

TBX3 SORBS2 ERG ITGA1 PCDH17 PTPRK

1.06e-051901166812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

TBX3 SORBS2 PDK4 ITGA1 PCDH17 PTPRK

1.06e-0519011667f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 TBX3 ITGA1 ST8SIA1 RUNX2 CPED1

1.06e-0519011662e592323085ba9c019d678ac2a784462ab470ed9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STARD13 TBX3 ITGA1 ST8SIA1 RUNX2 CPED1

1.06e-051901166445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

SOX9 IRX5 ENPP2 ST8SIA1 IRX1 MAPKAPK3

1.09e-05191116606107849463a1ccb78a5ccd3ae31619ef6bedda3
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

SORBS2 MYOM1 TRPM7 PDK4 SLC7A6 CPED1

1.12e-051921166ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 SOX9 PDK4 NBPF26 SLC14A1 ACSBG1

1.12e-05192116643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 ZNF609 SORBS2 ASH1L CUBN PTPRK

1.12e-051921166e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 SOX9 PDK4 NBPF26 SLC14A1 ACSBG1

1.16e-051931166b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 SOX9 PDK4 NBPF26 SLC14A1 ACSBG1

1.16e-05193116640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 SORBS2 IRX5 PDK4 ESRP1 IRX1

1.16e-05193116622ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 SOX10 SORBS2 IRX5 PDK4 IRX1

1.19e-0519411660ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERG MYOM1 ITGA1 CPED1 KCNT2 ZFHX3

1.19e-051941166ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CELF4 IRX5 C1QL4 BARHL1 BARHL2 ZFHX3

1.26e-0519611660767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCellSubstantia_nigra|World / BrainAtlas - Mouse McCarroll V32

IRX5 IRX1 CUBN DDC ZFHX3

1.28e-05115116518174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ENPP6 SORBS2 ERG ENPP2 PCDH17 TACR1

1.30e-0519711667a1a3839b2c965136663241b0d4e96c64cfb656a
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

FOXO1 SOX10 PDK4 ENPP2 SLC14A1 ACSBG1

1.41e-052001166e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial|GW16 / Sample Type, Dataset, Time_group, and Cell type.

STARD13 NFKBIZ ITGA1 CPED1 NFKB2 SLFN11

1.41e-05200116625f4c051c2e869481f33c22ad54de97efac444ad
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

STARD13 NFKBIZ ITGA1 CPED1 NFKB2 SLFN11

1.41e-052001166da45a85a4667965b24ba824af871157af5b4cd19
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Cck_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CDHR2 BARHL1 BARHL2 PAX9

4.20e-057411647c77b7d84fd8d9d823bbfc586f2b95865e75ab0b
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Cck_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CDHR2 BARHL1 BARHL2 PAX9

4.20e-05741164e008982158a3fbade8af9434eb32f20e00f92ba8
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CDHR2 BARHL1 BARHL2 PAX9

4.20e-05741164b4b961beb98ccf7551bb51773555615586da597d
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CDHR2 BARHL1 BARHL2 PAX9

4.20e-05741164ce00c59e0663093e33317227d31058a08db2d071
ToppCellSerous|World / shred by cell class for turbinate

SOX9 SOX10 TBX3 IRX4 SLC14A1

4.59e-0515011656a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCellCerebellum-Macroglia-ASTROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

SOX9 IRX5 IRX1 SLC14A1 ACSBG1

4.74e-05151116571841d2001200d1595c85c2b007ee20791a72927
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1|Cerebellum / BrainAtlas - Mouse McCarroll V32

SOX9 IRX5 IRX1 SLC14A1 ACSBG1

4.74e-05151116560aced0c1cc6b509b73308d03d58a3c44d712ef4
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

STARD13 SOX10 ENPP2 NBPF26 ITGA1

5.70e-0515711652c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX9 GARIN2 HCAR3 KCNT2 PTPRK

6.42e-0516111650d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCellBasal_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SOX9 IRX5 DDOST CSNK1A1L PAX9

6.81e-051631165679e25e5548d157d49a73057a3b5617dccda260f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX10 TBX3 SORBS2 PCDH17 ALK

7.01e-05164116557301178e420983c0cb72178e288a3a0449fdda3
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NFKBIZ ITGA1 NBPF20 MAPKAPK3 MMP8

7.01e-0516411651aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell15-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

SOX10 IRX1 IRX4 KIAA1549L PAX9

8.30e-05170116561f8dd5e27df1b8d01ccfd0d25247b34aa8d182c
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ENPP6 RUNX2 KIAA1549L LRRC7 TACR1

8.30e-051701165fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SORBS2 IRX5 CDHR2 ESRP1 IRX1

8.53e-051711165a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX10 TBX3 SORBS2 PCDH17 ALK

8.77e-051721165bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX9 GCNT3 TTLL12 RABL6 RPS6KA6

9.01e-05173116581c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCell(6)_Endothelial_cells-(6)_Endothelial-E|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

TBX3 ITGA1 PARP14 PCDH17 SLC14A1

9.26e-0517411654a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ERG ENPP2 KIAA1549L SLC14A1 TACR1

9.26e-0517411653d4c05ea5719ca65e85d1f15198453034791087c
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXO1 TBX3 ITGA1 KCNT2 SLC14A1

9.51e-0517511651799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FOXO1 ITGA1 ST8SIA1 RUNX2 INTS6

9.51e-0517511656374ab186d7ccf7f6dfb858267edba8962789e15
ToppCellfacs-GAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX10 ST8SIA1 RUNX2 PAX9 DNAH8

9.77e-051761165acd05ca8952710feedbfe377b1330f3c2406d044
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 GCNT3 PDK4 HCAR1 IRX1

1.00e-0417711651dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERG ASH1L ITGA1 PARP14 NR3C2

1.03e-04178116501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ENPP6 SOX10 VPS37A ENPP2 IRX1

1.03e-041781165b1357ceb84b83fab53c0394c1af73cbd009f571a
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

STARD13 TBX3 ERG ITGA1 PCDH17

1.09e-041801165b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellEndothelial-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

TBX3 ERG ITGA1 PCDH17 SLC14A1

1.09e-0418011654c3376169770ee9f9283daae44c17f35e46bfd19
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ENPP6 SOX10 IRX5 ESRP1

1.11e-049511640ac6cba7e0ed6083f777287f39a871461fa1bca4
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

TBX3 ERG ITGA1 PCDH17 SLC14A1

1.11e-04181116561608123959483ff60f07d8467996853c4371b6a
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX10 TBX3 PCDH17 NEK2 BARHL2

1.11e-041811165f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SOX10 TBX3 SORBS2 PCDH17 ACSBG1

1.14e-041821165d6740bca2b974122b8451989365a94a81140afd1
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ERG CPED1 CEP120 ZFHX3 LRRC7

1.17e-041831165e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FOXO1 HCAR2 NFKBIZ HCAR3 NFKB2

1.17e-041831165f9a3af96c0fb7d5c4d7df6db8b2c42e322418c08
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX9 SOX10 IRX5 ESRP1 IRX1

1.20e-041841165204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SORBS2 ERG ENPP2 PCDH17 SLC14A1

1.20e-041841165842473fa415575441b595073a994b6d621169776
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

ZBED4 SLFN13 XPNPEP3 PRKACA SLFN11

1.20e-0418411650e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX9 SOX10 IRX5 ESRP1 IRX1

1.20e-0418411659365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 SOX10 IRX5 ESRP1 IRX1

1.20e-0418411657cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 IRX5 IRX1 SLC14A1 ACSBG1

1.20e-041841165f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX9 SOX10 IRX5 ESRP1 IRX1

1.20e-04184116553b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 ITGA1 CPED1 PCDH17 ZFHX3

1.23e-04185116551dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

NEK10 PDK4 NEK2 CEP120 SLFN11

1.23e-0418511659a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

ZBED4 SLFN13 XPNPEP3 PRKACA SLFN11

1.23e-0418511651979d189c204f4c2893e3170a514ee7d5523406c
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

SORBS2 MYOM1 TRPM7 PDK4 CPED1

1.23e-0418511656baccb26f999145e51b91d94315bf8d4655bef31
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERG ST8SIA1 CEP120 ZFHX3 LRRC7

1.23e-0418511651ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYOM1 ITGA1 CPED1 PCDH17 ZFHX3

1.23e-041851165a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

TBX3 ERG ITGA1 PCDH17 SLC14A1

1.23e-041851165a28187c2fd23564314b35759479ff2ca21f61485
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SOX9 ERG ST8SIA1 CEP120 ZFHX3

1.27e-0418611657def03dd856b765bd3f493288641981c4f7fd26e
ToppCell343B-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 ITGA1 PARP14 PCDH17 PTPRK

1.27e-041861165dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SOX9 ERG ST8SIA1 ZFHX3 LRRC7

1.27e-0418611654d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SORBS2 IRX5 ESRP1 IRX1 NR3C2

1.27e-041861165bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

TBX3 ERG ENPP2 CUBN PCDH17

1.27e-0418611652e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

TBX3 ERG ENPP2 CUBN PCDH17

1.27e-041861165c3449e54454009973818fc1101933c6f0168258c
ToppCell343B-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TBX3 ITGA1 PARP14 PCDH17 PTPRK

1.27e-041861165080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PAPPA2 ST8SIA1 KCNT2 ZFHX3 LRRC7

1.30e-0418711655258674d0346e5c51a4b965efcdc1790c970845d
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HCAR2 IRX5 ESRP1 IRX1 PAX9

1.30e-041871165380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCelldroplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HCAR2 IRX5 ESRP1 IRX1 PAX9

1.30e-0418711655b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SORBS2 IRX5 ESRP1 IRX1 NR3C2

1.30e-041871165db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TBX3 ERG CPED1 CEP120 ZFHX3

1.30e-041871165387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 PDK4 NBPF26 SLC14A1 ACSBG1

1.30e-0418711655d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCellE12.5-Epithelial-epithelial_progenitor_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SOX10 SORBS2 IRX5 ESRP1 IRX1

1.30e-041871165ab6f4d387218b4651fdadbf269806c1ddc96a1d2
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX9 NBPF26 SLC14A1 ACSBG1 NFKB2

1.30e-041871165401be371b32066db926de3415bb4ce9465749dc3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TBX3 MYOM1 ITGA1 ST8SIA1 CPED1

1.30e-04187116515d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 PDK4 NBPF26 SLC14A1 ACSBG1

1.30e-0418711655c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FOXO1 PDK4 NBPF26 SLC14A1 ACSBG1

1.30e-04187116593c78fc7f126132eb84feb47be2c4e8c568b9e91
Diseasechemokine (C-C motif) ligand 27 measurement

STARD13 UBAP2 NEK10 NEK4 LRRC7

5.73e-06701075EFO_0008082
Diseasemucocutaneous lymph node syndrome

ENPP6 OR2B2 CUBN ZFHX3

1.72e-04761074EFO_0004246
DiseaseProstatic Neoplasms

FOXO1 TBX3 ERG ASH1L PTPRK PRKACB KMT2A ZFHX3 MMP13

4.15e-046161079C0033578
DiseaseMalignant neoplasm of prostate

FOXO1 TBX3 ERG ASH1L PTPRK PRKACB KMT2A ZFHX3 MMP13

4.15e-046161079C0376358
DiseaseOdontome

TBX3 RUNX2

5.75e-04101072C0524730
DiseaseTooth Abnormalities

TBX3 RUNX2

5.75e-04101072C0040427
Diseaseserum metabolite measurement

ENPP6 SORBS2 SLC7A6 CPED1 ABCA7 DDC LARP4B KCNT2 MAPKAPK3 ZFHX3 ALK

6.48e-0494510711EFO_0005653
Diseasecentral corneal thickness

FOXO1 OR5AS1 RUNX2 DISP3 KMT2A NR3C2

9.37e-043091076EFO_0005213
Diseaseglutaroyl carnitine measurement

SLC7A6 TACR1

9.90e-04131072EFO_0021005
Diseasetrimethylamine-N-oxide measurement

CUBN TAS1R2

1.15e-03141072EFO_0010541
DiseaseHypodontia

IRX5 PAX9

1.15e-03141072C0020608
DiseaseWithdrawal Symptoms

RUNX2 PER3 TACR1

1.24e-03581073C0087169
DiseaseDrug Withdrawal Symptoms

RUNX2 PER3 TACR1

1.24e-03581073C0086189
DiseaseSubstance Withdrawal Syndrome

RUNX2 PER3 TACR1

1.24e-03581073C0038587
Disease5-oxoproline measurement

CYC1 DNAH8

1.51e-03161072EFO_0010988
Diseasepro-hydroxy-pro measurement

NR3C2 ALK

1.51e-03161072EFO_0021132
Diseasearterial stiffness measurement

FOXO1 NEK10 PTPRK

1.64e-03641073EFO_0004517
DiseaseCraniofacial Abnormalities

SOX9 IRX5 RUNX2 MMP13

2.54e-031561074C0376634
DiseaseDisproportionate short stature

SOX9 RUNX2 MMP13

2.79e-03771073C0878659
DiseaseLung diseases

IRX5 IRX1 MMP8

2.90e-03781073C0024115
Diseasewhite matter microstructure measurement

SOX9 CELF4 OR2B2 OR2B3 RUNX2 CPED1

3.02e-033901076EFO_0005674
DiseaseOvarian Serous Adenocarcinoma

TRPM7 ALK

3.14e-03231072C1335177
DiseaseIntrahepatic Cholangiocarcinoma

PRKACA PRKACB

3.41e-03241072C0345905
Diseaseperiodontal measurement

ASH1L IRX1

3.41e-03241072EFO_0007780
DiseaseExtrahepatic Cholangiocarcinoma

PRKACA PRKACB

3.41e-03241072C3805278
Diseaseobsolete aging

GCNT3 LARP4B BARHL2 TAS1R2 ZFHX3

3.54e-032791075GO_0007568

Protein segments in the cluster

PeptideGeneStartEntry
YTAGPQPLNTFYKAM

SLC33A1

366

O00400
YFRTFPMPSNKSYVV

C21orf62

201

Q9NYP8
FPLSSTGFYPSYGMP

ASH1L

1371

Q9NR48
SYCSPPSSLMTYFFP

DISP3

331

Q9P2K9
LLTFDIGYGSFMYPV

CPED1

361

A4D0V7
FTCPMPGVYFFAYHV

C1QL4

146

Q86Z23
SSLYKYPSDLPYMGS

ERG

406

P11308
SALQRMFPSPYFYPQ

BARHL1

251

Q9BZE3
MFPSPYFYPQSLVSN

BARHL1

256

Q9BZE3
LYFNPYFPGQAIAMA

CYC1

231

P08574
FFAYFPTASSYPAML

DDC

76

P20711
YGWSITPLMYPASFF

ABCA7

1626

Q8IZY2
PSTAYYPAGTQLFMN

ESRP1

586

Q6NXG1
PGALMYPNYAFRETS

MMP8

231

P22894
VSSPSLATSPMYFDY

PCDH17

786

O14917
PPGSSYFRYAESSMK

RABL6

201

Q3YEC7
LSYMPRAASAAFPYG

RFWD3

591

Q6PCD5
SFESYLKTMPPYYLG

INTS6

411

Q9UL03
FGYPYSSAPQFLMAT

IRX4

6

P78413
MSYPQGYLYQPSASL

IRX5

1

P78411
FFGSITFMYFKPPSS

OR8D1

251

Q8WZ84
LMFGPSIYIYARPFD

OR4M2B

251

A0A0X1KG70
LFSYTYSTAPTPVMD

PDK4

306

Q16654
FYSLFNPMLNPLIYS

OR2A14

276

Q96R47
FYGTAIYMYLQPPSS

OR2B3

251

O76000
AQVSPYMTYSAAPSG

PAX9

281

P55771
FFGSITFMYFKPPSS

OR8D2

251

Q9GZM6
GVLIYEMAAGYPPFF

PRKACA

226

P17612
MTSPLNLSYFYGASP

NFKBIZ

26

Q9BYH8
TVNPFPFMDGSYFSF

NR3C2

446

P08235
IMYILLCGFPPFYSN

MAPKAPK3

231

Q16644
SFAKTFVGTPYYMSP

NEK2

171

P51955
YRGYPPMEQMFSFSQ

LRRC7

1076

Q96NW7
NSMLDPVVYYFSSPS

HCAR2

286

Q8TDS4
QYPYIPPMTEFFFDG

CFAP65

626

Q6ZU64
RYATSFYFPPMYSPQ

LARP4B

336

Q92615
YTLPAFYMGNFSIPS

GLB1

546

P16278
YPAFPFPYLDTFMTV

PER3

836

P56645
GCILYQMATLSPPFY

NEK10

716

Q6ZWH5
FPIYTYTGKSHFMLP

MMP13

241

P45452
ISPALGSPMYLFLSY

OR4C45

46

A6NMZ5
LMFGPSIYIYARPFD

OR4M1

251

Q8NGD0
LMFGPSIYIYARPFD

OR4M2

251

Q8NGB6
SLGSPMYFFLSYLSF

OR4X2

46

Q8NGF9
LIGTPYYMSPELFSN

NEK4

166

P51957
MFEPSFCFYTGYKIP

DNAH8

4141

Q96JB1
GAVHTAFPFTPTYMY

KIAA1549L

701

Q6ZVL6
AFPFTPTYMYARTGH

KIAA1549L

706

Q6ZVL6
LFYTMLAGYTPFANG

RPS6KA6

611

Q9UK32
SLGYVFMYFNRTSLP

CSNK1A1L

206

Q8N752
MSSNLEYAKGYPPYS

KCNT2

661

Q6UVM3
LFYGSGIFTYMRPNS

OR2D3

266

Q8NGH3
PSLRSPMYFFLAYLS

OR4C13

51

Q8NGP0
FPNMTSNGYPVLYPT

ITGA1

1006

P56199
FIPSAYPYYASAFSM

DDOST

421

P39656
YSTPSMYFELPDSFQ

NBPF1

1156

Q3BBV0
FYGALLFMYLQPTTS

OR5AS1

251

Q8N127
NKMPLSVFPYYASLG

PARP14

291

Q460N5
TRFPGAPFTNYMSYT

PAPPA2

796

Q9BXP8
TFYMAEGIFNSPGYP

CUBN

1741

O60494
DPLTYGMSGPNAYFF

CDHR2

56

Q9BYE9
YQKYTYGQSSMSPLP

FOXO1

421

Q12778
GVLIYEMAAGYPPFF

PRKACB

226

P22694
YFSAPGVMNFGNPSY

CASC3

621

O15234
LRYSYPFFGSAAPIM

CEP120

476

Q8N960
VAINGSFPSIYMPYN

ENPP3

276

O14638
SFPSIYMPYNGSVPF

ENPP3

281

O14638
PPYNLTMFTGNAYIV

GCNT3

286

O95395
GPHFMSSPYNYRLYS

ACSBG1

481

Q96GR2
AGNYSALQRMFPSPY

BARHL2

301

Q9NY43
PSFASSYQAMPGYLD

HOXC13

176

P31276
NMFFGLTPLYGVRSY

KMT2A

2626

Q03164
SMLDPLVYYFSSPSF

HCAR1

271

Q9BXC0
DFPSLSYPNYYTLMT

ENPP6

66

Q6UWR7
SPMDYPASYSLAGTQ

SLFN13

531

Q68D06
IYSCMGFSPQAYPAF

C3orf56

61

Q8N813
MSYGFLFPPYLSSSP

ENPP2

676

Q13822
AMSGGAPYYFAAELP

PTPRK

661

Q15262
FYGTAISMYLQPPSP

OR2B2

251

Q9GZK3
FTAILTPYMYAGTGP

GARIN2

211

Q8N9W8
YYGTSSGSYQFPMVP

RUNX2

446

Q13950
PSHLMSQQYRPYSFF

MRPS5

76

P82675
MFSQVPRTPASGCYY

STARD13

1

Q9Y3M8
LFFTYQGIPYPITMC

SULT6B1

26

Q6IMI4
TMLYGQFPFYDSIPQ

STK40

266

Q8N2I9
GLAMSPFGSLFPYPY

TBX3

591

O15119
PFGSLFPYPYTYMAA

TBX3

596

O15119
SFYLFHPLAYGMVGP

POMT2

716

Q9UKY4
TPSMYFELPDSFQHY

NBPF12

1401

Q5TAG4
TPSMYFELPDSFQHY

NBPF20

5151

P0DPF2
TPSMYFELPDSFQHY

NBPF26

846

B4DH59
MQAYSNPGYSSFPSP

RFFL

26

Q8WZ73
MSFPQLGYPQYLSAA

IRX1

1

P78414
IFYGTIIFMYPQPKS

OR5AL1

266

P0C617
TIPYMYGFLSGFSQS

OR5M1

146

Q8NGP8
NSMLDPVVYYFSSPS

HCAR3

286

P49019
LAFPQGYYSTTETMP

TACR1

161

P25103
YNPTYETMFAPEFGP

CDC40

81

O60508
YYDNVLPFSGFHAMP

ST8SIA1

311

Q92185
SPMDYPASYSLAGTQ

SLFN11

531

Q7Z7L1
PLCTFYFSNMLGFYP

MT-ND5

516

P03915
GLYSTFTYMNPAQRP

SOX9

461

P48436
MSYYQRPFSPSAYSL

SORBS2

1

O94875
EIFSLGYMPYPSKSN

ALK

1321

Q9UM73
FNPMAIPFGAYGAYA

CELF4

251

Q9BZC1
TSFPFNFSYSDYDMP

PROKR1

31

Q8TCW9
SYTGLPYYTGMPSAF

UBAP2

911

Q5T6F2
LYSAFSYMGPSQRPL

SOX10

421

P56693
MMQNYPGSYLPSSYS

ZNF609

1251

O15014
MPSPQFIKSYFSSFT

TOMM70

251

O94826
MYLSATGHYNPFFPA

SLC14A1

186

Q13336
TAPFFYMPQQVAYTL

TTLL12

211

Q14166
LFYPERNTPAYFNSM

TAS1R2

816

Q8TE23
LLVPMYYIPAGSFSG

SLC35F6

226

Q8N357
GAAAAMSSPPQYYTI

TMEM174

171

Q8WUU8
GVPFYFMGVYLPESR

SLC7A6

461

Q92536
SNPTYYMSNDIPYTF

XPNPEP3

101

Q9NQH7
AGLYPSARSMFSPYR

PRR23C

176

Q6ZRP0
LTSPFKPAMDTNYYY

TRPM7

1541

Q96QT4
AFPYLYSNPSGMSPY

VPS37A

136

Q8NEZ2
MSDSYLPSYYSPSIG

YTHDF2

51

Q9Y5A9
YGMEGLFPYSPALSQ

ZFHX3

3336

Q15911
APSYFSRTAIPGMYD

ZBED4

696

O75132
STMPLSFGVTPYGYA

MYOM1

386

P52179
LGFFPSSLAYSPYQS

NFKB2

376

Q00653