| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | transporter activity | APOL3 NPC1 PEX2 SLC17A2 SLC6A11 MFSD4A SLC49A3 KCNA4 KCNA6 SLC7A7 SLC7A6 SLC2A8 SV2A MFSD12 SLC16A10 | 2.44e-08 | 1289 | 42 | 15 | GO:0005215 |
| GeneOntologyMolecularFunction | transmembrane transporter activity | APOL3 PEX2 SLC17A2 SLC6A11 MFSD4A SLC49A3 KCNA4 KCNA6 SLC7A7 SLC7A6 SLC2A8 SV2A MFSD12 SLC16A10 | 6.51e-08 | 1180 | 42 | 14 | GO:0022857 |
| GeneOntologyMolecularFunction | amino acid transmembrane transporter activity | 2.66e-06 | 105 | 42 | 5 | GO:0015171 | |
| GeneOntologyMolecularFunction | organic cation transmembrane transporter activity | 2.75e-05 | 83 | 42 | 4 | GO:0015101 | |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | 3.19e-05 | 293 | 42 | 6 | GO:0008514 | |
| GeneOntologyMolecularFunction | secondary active transmembrane transporter activity | 3.38e-05 | 296 | 42 | 6 | GO:0015291 | |
| GeneOntologyMolecularFunction | carboxylic acid transmembrane transporter activity | 7.10e-05 | 207 | 42 | 5 | GO:0046943 | |
| GeneOntologyMolecularFunction | organic acid transmembrane transporter activity | 7.27e-05 | 208 | 42 | 5 | GO:0005342 | |
| GeneOntologyMolecularFunction | odorant binding | 1.45e-04 | 127 | 42 | 4 | GO:0005549 | |
| GeneOntologyMolecularFunction | L-arginine transmembrane transporter activity | 3.32e-04 | 13 | 42 | 2 | GO:0061459 | |
| GeneOntologyMolecularFunction | G protein-coupled receptor activity | 4.42e-04 | 884 | 42 | 8 | GO:0004930 | |
| GeneOntologyMolecularFunction | L-amino acid transmembrane transporter activity | 4.48e-04 | 71 | 42 | 3 | GO:0015179 | |
| GeneOntologyMolecularFunction | active transmembrane transporter activity | 4.55e-04 | 477 | 42 | 6 | GO:0022804 | |
| GeneOntologyMolecularFunction | basic amino acid transmembrane transporter activity | 8.01e-04 | 20 | 42 | 2 | GO:0015174 | |
| GeneOntologyMolecularFunction | D-glucose transmembrane transporter activity | 1.26e-03 | 25 | 42 | 2 | GO:0055056 | |
| GeneOntologyMolecularFunction | hexose transmembrane transporter activity | 1.26e-03 | 25 | 42 | 2 | GO:0015149 | |
| GeneOntologyMolecularFunction | monosaccharide transmembrane transporter activity | 1.47e-03 | 27 | 42 | 2 | GO:0015145 | |
| GeneOntologyMolecularFunction | delayed rectifier potassium channel activity | 1.58e-03 | 28 | 42 | 2 | GO:0005251 | |
| GeneOntologyMolecularFunction | sugar transmembrane transporter activity | 1.69e-03 | 29 | 42 | 2 | GO:0051119 | |
| GeneOntologyMolecularFunction | transmembrane signaling receptor activity | 1.70e-03 | 1353 | 42 | 9 | GO:0004888 | |
| GeneOntologyMolecularFunction | carbohydrate transmembrane transporter activity | 3.53e-03 | 42 | 42 | 2 | GO:0015144 | |
| GeneOntologyMolecularFunction | G-protein alpha-subunit binding | 3.69e-03 | 43 | 42 | 2 | GO:0001965 | |
| GeneOntologyMolecularFunction | symporter activity | 3.85e-03 | 150 | 42 | 3 | GO:0015293 | |
| GeneOntologyMolecularFunction | inorganic anion transmembrane transporter activity | 5.55e-03 | 171 | 42 | 3 | GO:0015103 | |
| GeneOntologyMolecularFunction | sulfur compound transmembrane transporter activity | 7.31e-03 | 61 | 42 | 2 | GO:1901682 | |
| GeneOntologyMolecularFunction | amino acid binding | 1.03e-02 | 73 | 42 | 2 | GO:0016597 | |
| GeneOntologyBiologicalProcess | amino acid transport | 4.04e-09 | 195 | 41 | 8 | GO:0006865 | |
| GeneOntologyBiologicalProcess | organic anion transport | SLC17A2 SLC6A11 PRKCD HTR1A SLC7A7 SLC7A6 SLC2A8 SV2A MFSD12 SLC16A10 | 4.83e-08 | 515 | 41 | 10 | GO:0015711 |
| GeneOntologyBiologicalProcess | amino acid transmembrane transport | 1.30e-07 | 120 | 41 | 6 | GO:0003333 | |
| GeneOntologyBiologicalProcess | carboxylic acid transport | 1.22e-06 | 410 | 41 | 8 | GO:0046942 | |
| GeneOntologyBiologicalProcess | organic acid transport | 1.27e-06 | 412 | 41 | 8 | GO:0015849 | |
| GeneOntologyBiologicalProcess | organic acid transmembrane transport | 1.94e-05 | 167 | 41 | 5 | GO:1903825 | |
| GeneOntologyBiologicalProcess | gamma-aminobutyric acid transport | 2.31e-05 | 28 | 41 | 3 | GO:0015812 | |
| GeneOntologyBiologicalProcess | L-leucine transport | 1.72e-04 | 10 | 41 | 2 | GO:0015820 | |
| GeneOntologyBiologicalProcess | organic cation transport | 1.94e-04 | 145 | 41 | 4 | GO:0015695 | |
| GeneOntologyBiologicalProcess | collagen metabolic process | 2.10e-04 | 148 | 41 | 4 | GO:0032963 | |
| GeneOntologyBiologicalProcess | neutral amino acid transport | 2.31e-04 | 60 | 41 | 3 | GO:0015804 | |
| GeneOntologyBiologicalProcess | regulation of gamma-aminobutyric acid secretion | 2.97e-04 | 13 | 41 | 2 | GO:0014052 | |
| GeneOntologyBiologicalProcess | carboxylic acid transmembrane transport | 3.03e-04 | 163 | 41 | 4 | GO:1905039 | |
| GeneOntologyBiologicalProcess | G protein-coupled receptor signaling pathway | 3.14e-04 | 1395 | 41 | 10 | GO:0007186 | |
| GeneOntologyBiologicalProcess | branched-chain amino acid transport | 3.46e-04 | 14 | 41 | 2 | GO:0015803 | |
| GeneOntologyBiologicalProcess | L-arginine transmembrane transport | 3.98e-04 | 15 | 41 | 2 | GO:1903826 | |
| GeneOntologyBiologicalProcess | carbohydrate transport | 5.00e-04 | 186 | 41 | 4 | GO:0008643 | |
| HumanPheno | Membranous nephropathy | 2.08e-05 | 4 | 10 | 2 | HP:0012578 | |
| Domain | MFS | 3.40e-09 | 108 | 41 | 7 | PS50850 | |
| Domain | MFS_dom | 1.53e-08 | 134 | 41 | 7 | IPR020846 | |
| Domain | MFS | 1.61e-08 | 77 | 41 | 6 | IPR011701 | |
| Domain | MFS_1 | 1.61e-08 | 77 | 41 | 6 | PF07690 | |
| Domain | K_chnl_volt-dep_Kv1 | 1.31e-04 | 8 | 41 | 2 | IPR003972 | |
| Domain | AA/rel_permease1 | 3.61e-04 | 13 | 41 | 2 | IPR002293 | |
| Domain | AA_permease_2 | 3.61e-04 | 13 | 41 | 2 | PF13520 | |
| Domain | AA-permease/SLC12A_dom | 1.06e-03 | 22 | 41 | 2 | IPR004841 | |
| Domain | AA_permease | 1.06e-03 | 22 | 41 | 2 | PF00324 | |
| Domain | K_chnl_volt-dep_Kv | 1.59e-03 | 27 | 41 | 2 | IPR003968 | |
| Domain | Sugar_transporter_CS | 2.24e-03 | 32 | 41 | 2 | IPR005829 | |
| Domain | VG_K_chnl | 2.38e-03 | 33 | 41 | 2 | IPR028325 | |
| Domain | Sugar_tr | 2.83e-03 | 36 | 41 | 2 | PF00083 | |
| Domain | MFS_sugar_transport-like | 2.83e-03 | 36 | 41 | 2 | IPR005828 | |
| Domain | GPCR_Rhodpsn_7TM | 3.21e-03 | 670 | 41 | 6 | IPR017452 | |
| Domain | 7tm_1 | 3.38e-03 | 677 | 41 | 6 | PF00001 | |
| Domain | G_PROTEIN_RECEP_F1_1 | 3.58e-03 | 685 | 41 | 6 | PS00237 | |
| Domain | G_PROTEIN_RECEP_F1_2 | 3.74e-03 | 691 | 41 | 6 | PS50262 | |
| Domain | GPCR_Rhodpsn | 3.77e-03 | 692 | 41 | 6 | IPR000276 | |
| Domain | BTB_2 | 6.04e-03 | 53 | 41 | 2 | PF02214 | |
| Domain | T1-type_BTB | 6.04e-03 | 53 | 41 | 2 | IPR003131 | |
| Domain | Channel_four-helix_dom | 6.95e-03 | 57 | 41 | 2 | IPR027359 | |
| Domain | - | 6.95e-03 | 57 | 41 | 2 | 1.20.120.350 | |
| Domain | C1_1 | 6.95e-03 | 57 | 41 | 2 | PF00130 | |
| Domain | ZF_DAG_PE_1 | 8.70e-03 | 64 | 41 | 2 | PS00479 | |
| Domain | ZF_DAG_PE_2 | 8.70e-03 | 64 | 41 | 2 | PS50081 | |
| Domain | C1 | 8.96e-03 | 65 | 41 | 2 | SM00109 | |
| Domain | PE/DAG-bd | 9.23e-03 | 66 | 41 | 2 | IPR002219 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 7.21e-05 | 32 | 36 | 3 | MM14957 | |
| Pathway | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 7.92e-05 | 33 | 36 | 3 | M188 | |
| Pubmed | 1.42e-06 | 2 | 42 | 2 | 15756301 | ||
| Pubmed | 1.42e-06 | 2 | 42 | 2 | 31705628 | ||
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 20388733 | ||
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 26603102 | ||
| Pubmed | Genome-wide interrogation of longitudinal FEV1 in children with asthma. | 4.27e-06 | 3 | 42 | 2 | 25221879 | |
| Pubmed | 4.27e-06 | 3 | 42 | 2 | 21159880 | ||
| Pubmed | Amino acid transport across mammalian intestinal and renal epithelia. | 7.19e-06 | 31 | 42 | 3 | 18195088 | |
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 9829974 | ||
| Pubmed | 8.53e-06 | 4 | 42 | 2 | 9878049 | ||
| Pubmed | Truncation of the Shaker-like voltage-gated potassium channel, Kv1.1, causes megencephaly. | 2.13e-05 | 6 | 42 | 2 | 14686897 | |
| Pubmed | 2.13e-05 | 6 | 42 | 2 | 18625718 | ||
| Pubmed | 2.98e-05 | 7 | 42 | 2 | 27619418 | ||
| Pubmed | CoREST is an integral component of the CoREST- human histone deacetylase complex. | 3.97e-05 | 8 | 42 | 2 | 11171972 | |
| Pubmed | 3.97e-05 | 8 | 42 | 2 | 19754958 | ||
| Pubmed | 5.10e-05 | 9 | 42 | 2 | 15901826 | ||
| Pubmed | 5.10e-05 | 9 | 42 | 2 | 21264952 | ||
| Pubmed | Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells. | 6.37e-05 | 10 | 42 | 2 | 1383027 | |
| Pubmed | 9.32e-05 | 12 | 42 | 2 | 17967884 | ||
| Pubmed | Odorant and vomeronasal receptor genes in two mouse genome assemblies. | 1.00e-04 | 74 | 42 | 3 | 15081110 | |
| Pubmed | A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export. | 1.07e-04 | 392 | 42 | 5 | 33144569 | |
| Pubmed | HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases. | 1.10e-04 | 13 | 42 | 2 | 23317503 | |
| Pubmed | 1.10e-04 | 13 | 42 | 2 | 23637329 | ||
| Pubmed | An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. | 1.10e-04 | 13 | 42 | 2 | 16079794 | |
| Pubmed | DEFOG: a practical scheme for deciphering families of genes. | 1.42e-04 | 219 | 42 | 4 | 12213199 | |
| Pubmed | Coordinated histone modifications mediated by a CtBP co-repressor complex. | 1.48e-04 | 15 | 42 | 2 | 12700765 | |
| Pubmed | Systematic protein-protein interaction mapping for clinically relevant human GPCRs. | 1.80e-04 | 697 | 42 | 6 | 28298427 | |
| Pubmed | 2.15e-04 | 18 | 42 | 2 | 12493763 | ||
| Pubmed | An integrated genetic map of the pearl locus of mouse chromosome 13. | 2.40e-04 | 19 | 42 | 2 | 8828042 | |
| Pubmed | Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. | 2.56e-04 | 1061 | 42 | 7 | 33845483 | |
| Pubmed | RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer. | 4.20e-04 | 25 | 42 | 2 | 31636387 | |
| Pubmed | 4.54e-04 | 26 | 42 | 2 | 7905852 | ||
| Pubmed | 4.54e-04 | 26 | 42 | 2 | 30378028 | ||
| Pubmed | Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. | 4.70e-04 | 125 | 42 | 3 | 32891193 | |
| Pubmed | 4.81e-04 | 126 | 42 | 3 | 17897319 | ||
| Pubmed | 5.28e-04 | 28 | 42 | 2 | 22002062 | ||
| Pubmed | 6.47e-04 | 31 | 42 | 2 | 29846670 | ||
| Pubmed | ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma. | 7.34e-04 | 33 | 42 | 2 | 36414381 | |
| Pubmed | Different evolutionary processes shaped the mouse and human olfactory receptor gene families. | 7.49e-04 | 340 | 42 | 4 | 11875048 | |
| Pubmed | 7.49e-04 | 340 | 42 | 4 | 11802173 | ||
| Pubmed | 7.74e-04 | 343 | 42 | 4 | 32295537 | ||
| Pubmed | 8.00e-04 | 346 | 42 | 4 | 14611657 | ||
| Pubmed | 8.33e-04 | 1293 | 42 | 7 | 15342556 | ||
| Pubmed | 8.74e-04 | 36 | 42 | 2 | 35167946 | ||
| Pubmed | Ion channel expression in the developing enteric nervous system. | 9.23e-04 | 37 | 42 | 2 | 25798587 | |
| Pubmed | 9.74e-04 | 38 | 42 | 2 | 33283408 | ||
| Pubmed | 1.04e-03 | 371 | 42 | 4 | 25241761 | ||
| Pubmed | 1.08e-03 | 40 | 42 | 2 | 16382104 | ||
| GeneFamily | Solute carriers | 2.97e-06 | 395 | 30 | 7 | 752 | |
| GeneFamily | Potassium voltage-gated channels | 2.00e-03 | 40 | 30 | 2 | 274 | |
| Coexpression | ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_DN | 1.43e-05 | 4 | 41 | 2 | MM459 | |
| ToppCell | 10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group | 1.03e-06 | 198 | 41 | 5 | 641e7be258303bb9782d19fcf8693f317581d3b8 | |
| Drug | dopamine | 4.02e-06 | 715 | 41 | 9 | CID000000681 | |
| Drug | sodium | SLC17A2 SLC6A11 PRKCD KCNA4 KCNA6 SLC7A7 SLC7A6 SLC2A8 ADCY9 SLC16A10 | 4.97e-06 | 944 | 41 | 10 | CID000000923 |
| Drug | AC1L1B9H | 1.17e-05 | 78 | 41 | 4 | CID000001341 | |
| Drug | BBCH | 1.54e-05 | 27 | 41 | 3 | CID000115288 | |
| Drug | staurosporine; Down 200; 0.1uM; MCF7; HG-U133A | 1.93e-05 | 184 | 41 | 5 | 423_DN | |
| Drug | Thalictruberine | 3.15e-05 | 5 | 41 | 2 | CID000181743 | |
| Disease | Liver Cirrhosis | 1.28e-05 | 103 | 41 | 4 | C0023890 | |
| Disease | Fibrosis, Liver | 1.39e-05 | 105 | 41 | 4 | C0239946 | |
| Disease | non-high density lipoprotein cholesterol measurement | 4.26e-04 | 713 | 41 | 6 | EFO_0005689 | |
| Disease | anxiety disorder (implicated_via_orthology) | 4.28e-04 | 22 | 41 | 2 | DOID:2030 (implicated_via_orthology) | |
| Disease | pulmonary function measurement, forced expiratory volume | 1.22e-03 | 37 | 41 | 2 | EFO_0003892, EFO_0004314 | |
| Disease | epilepsy (implicated_via_orthology) | 1.51e-03 | 163 | 41 | 3 | DOID:1826 (implicated_via_orthology) | |
| Disease | ejection fraction measurement | 1.64e-03 | 43 | 41 | 2 | EFO_0005527 | |
| Disease | non-alcoholic fatty liver disease | 2.07e-03 | 182 | 41 | 3 | EFO_0003095 | |
| Disease | comparative body size at age 10, self-reported | 2.70e-03 | 420 | 41 | 4 | EFO_0009819 | |
| Disease | Seizures | 3.45e-03 | 218 | 41 | 3 | C0036572 | |
| Disease | mean corpuscular hemoglobin concentration | 3.99e-03 | 1105 | 41 | 6 | EFO_0004528 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| FLAIILFPFGFICCF | 96 | O95415 | |
| TCPFCFGPFVTTEAY | 876 | Q6IQ32 | |
| GFICEFCQNTTVIFP | 601 | Q9H714 | |
| SIPFYGCALQFLVFC | 91 | Q8NH69 | |
| FSPESCQIFFGITAC | 91 | Q6ZW49 | |
| FFLFTICAGTECFLL | 101 | Q8NGQ6 | |
| FLVCGVIFGCLAFTF | 466 | Q8N468 | |
| FIATFFGQPTFCSVC | 161 | Q05655 | |
| FFGCTFVAFGPAFAL | 6 | Q96BI3 | |
| SFLFDVYFTCPKCGT | 271 | P28328 | |
| FCRATFSFCVSPLLV | 321 | Q86XP1 | |
| AAVFCIFIICFGPTN | 316 | P25116 | |
| FLFGVLFAICFSCLA | 121 | Q9NQ84 | |
| CVRNPGCVIFFSLVF | 346 | O15118 | |
| VCRECFTPFVNGSFF | 501 | P49023 | |
| GSFFTDPFFLVETLC | 256 | P17658 | |
| FFLPLAITAFCYVGC | 191 | O14842 | |
| FFIVALVLPFCESSC | 361 | P08908 | |
| GIFTCFDILFFDPAI | 241 | P43251 | |
| VAPALCFLLVCVGFF | 146 | O60503 | |
| CFLLVCVGFFLFTFT | 151 | O60503 | |
| CCQVVTFTFPFGFQG | 21 | O95236 | |
| CKFFCVPRDFTAFAL | 101 | O75072 | |
| CPVFDGLFEFCQLST | 101 | Q92769 | |
| TVCVLLSFPFIFSPC | 101 | Q6NUT3 | |
| VTSVFGLPFCDAFVI | 161 | Q5JRS4 | |
| FCGSSVIPQFFCDVP | 166 | Q96R54 | |
| CPGFSLGCFFFLTAL | 256 | Q96GQ5 | |
| CDFCYEFPFPTVATT | 286 | O75900 | |
| AFCIFSVLFTLFCVP | 446 | Q9NY64 | |
| LCFTVDFALGFTCFE | 441 | Q9NY99 | |
| FVLVCAFPSVFAIGA | 336 | Q7L0J3 | |
| CTFFSCILAVFFHTP | 431 | Q6UXD7 | |
| LSVFFPIVFCLCTIF | 416 | Q9UM01 | |
| FIFYIFGSTGCVCCL | 211 | O00624 | |
| GAFLIPYVVFFICCG | 86 | P48066 | |
| PYVVFFICCGIPVFF | 91 | P48066 | |
| FICCGIPVFFLETAL | 96 | P48066 | |
| FACFFICLITDPFLD | 226 | Q9H0V1 | |
| VFFPIVFCICSVFLV | 426 | Q92536 | |
| TCPFCTFKTFYPEVL | 711 | O75362 | |
| FGAFCPDIFLNTLSC | 226 | Q2T9J0 | |
| DTCFEFGVFPAILSF | 46 | P60604 | |
| FVVRCFACPSQALFF | 386 | P22459 | |
| FFCCPIVSVFTDLFG | 126 | Q8TF71 |