Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH2 DNAH8

1.03e-04181033GO:0008569
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD3 PCID2

8.73e-05181023GO:0044615
GeneOntologyCellularComponentgamma-tubulin complex

TUBG2 TUBG1 MARK4

1.41e-04211023GO:0000930
GeneOntologyCellularComponentpolar microtubule

TUBG1 KLHL22

2.34e-0451022GO:0005827
GeneOntologyCellularComponentaxonemal dynein complex

DNAH10 DNAH2 DNAH8

2.40e-04251023GO:0005858
GeneOntologyCellularComponentpericentriolar material

TUBG2 TUBG1 AKAP9

3.38e-04281023GO:0000242
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD3

6.48e-0481022GO:1990723
GeneOntologyCellularComponentinner dynein arm

DNAH10 DNAH2

1.03e-03101022GO:0036156
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD3

1.03e-03101022GO:0044614
MousePhenopregnancy-related premature death

KALRN INHBB AP3B1 SPAG17

1.13e-0523874MP:0008028
DomainTPR_REGION

RGPD4 TANC2 DNAH10 DNAH2 FIS1 RGPD3 GPSM2 EDRF1

2.92e-061651008PS50293
DomainTPR

RGPD4 TANC2 DNAH10 DNAH2 FIS1 RGPD3 GPSM2 EDRF1

2.92e-061651008PS50005
DomainDHC_N1

DNAH10 DNAH2 DNAH8

8.18e-0681003PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH2 DNAH8

8.18e-0681003IPR013594
DomainGamma_tubulin

TUBG2 TUBG1

2.84e-0521002IPR002454
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH2 DNAH8

5.19e-05141003IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH2 DNAH8

5.19e-05141003IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH2 DNAH8

5.19e-05141003IPR013602
DomainDHC_N2

DNAH10 DNAH2 DNAH8

5.19e-05141003PF08393
DomainMT

DNAH10 DNAH2 DNAH8

5.19e-05141003PF12777
DomainAAA_8

DNAH10 DNAH2 DNAH8

5.19e-05141003PF12780
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH2 DNAH8

5.19e-05141003IPR011704
DomainAAA_5

DNAH10 DNAH2 DNAH8

5.19e-05141003PF07728
DomainDHC_fam

DNAH10 DNAH2 DNAH8

6.47e-05151003IPR026983
DomainDynein_heavy_dom

DNAH10 DNAH2 DNAH8

6.47e-05151003IPR004273
DomainDynein_heavy

DNAH10 DNAH2 DNAH8

6.47e-05151003PF03028
DomainTPR-contain_dom

RGPD4 TANC2 FIS1 RGPD3 GPSM2 EDRF1

1.56e-041501006IPR013026
DomainTyr_kinase_CSF1/PDGF_rcpt

FLT3 PDGFRB

4.20e-0461002IPR016243
DomainFYVE

ZFYVE27 FGD2 PLEKHF1

4.92e-04291003PF01363
DomainFYVE

ZFYVE27 FGD2 PLEKHF1

4.92e-04291003SM00064
DomainGCC2_Rab_bind

RGPD4 RGPD3

5.86e-0471002IPR032023
DomainRab_bind

RGPD4 RGPD3

5.86e-0471002PF16704
DomainTyr_kinase_rcpt_3_CS

FLT3 PDGFRB

7.78e-0481002IPR001824
DomainRECEPTOR_TYR_KIN_III

FLT3 PDGFRB

7.78e-0481002PS00240
DomainZnf_FYVE-rel

ZFYVE27 FGD2 PLEKHF1

7.90e-04341003IPR017455
Domain-

RGPD4 TANC2 FIS1 RGPD3 GPSM2 EDRF1

8.65e-0420710061.25.40.10
DomainZnf_FYVE

ZFYVE27 FGD2 PLEKHF1

1.10e-03381003IPR000306
Domain-

RGPD4 RGPD3

1.24e-031010021.10.220.60
DomainZF_FYVE

ZFYVE27 FGD2 PLEKHF1

1.27e-03401003PS50178
DomainGrip

RGPD4 RGPD3

1.51e-03111002SM00755
DomainGRIP

RGPD4 RGPD3

1.51e-03111002PF01465
DomainTPR-like_helical_dom

RGPD4 TANC2 FIS1 RGPD3 GPSM2 EDRF1

1.59e-032331006IPR011990
DomainRan_BP1

RGPD4 RGPD3

1.81e-03121002PF00638
DomainGRIP_dom

RGPD4 RGPD3

1.81e-03121002IPR000237
DomainGRIP

RGPD4 RGPD3

1.81e-03121002PS50913
DomainRANBD1

RGPD4 RGPD3

1.81e-03121002PS50196
DomainRanBD

RGPD4 RGPD3

2.13e-03131002SM00160
DomainRan_bind_dom

RGPD4 RGPD3

2.13e-03131002IPR000156
DomainChemokine_rcpt

CCRL2 CCR7

3.24e-03161002IPR000355
DomainProtein_kinase_ATP_BS

FLT3 KALRN PDGFRB HUNK MARK4 MAPK4 NLK

4.27e-033791007IPR017441
Domain-

RGPD4 FGD2 KALRN PLEKHF1 ARHGEF12 RGPD3 FRMD3

5.05e-0339110072.30.29.30
Domain-

TUBG2 TUBG1

5.06e-032010023.30.1330.20
DomainTPR

RGPD4 TANC2 RGPD3 GPSM2

5.11e-031291004SM00028
Domain-

TUBG2 TUBG1

5.58e-032110021.10.287.600
DomainTPR_repeat

RGPD4 TANC2 RGPD3 GPSM2

5.69e-031331004IPR019734
DomainRhoGEF

FGD2 KALRN ARHGEF12

5.80e-03681003SM00325
DomainTubulin_C

TUBG2 TUBG1

6.11e-03221002SM00865
DomainTubulin_C

TUBG2 TUBG1

6.11e-03221002PF03953
Pubmed

Piezo mechanosensory channels regulate centrosome integrity and mitotic entry.

TUBG2 TUBG1 PIEZO2

1.07e-074105336574677
Pubmed

Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium.

TUBG2 IFT74 TUBG1

2.66e-075105321285373
Pubmed

Mammalian RanBP1 regulates centrosome cohesion during mitosis.

TUBG2 TUBG1 AKAP9

9.28e-077105312840069
Pubmed

The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblasts.

OFD1 TUBG2 TUBG1

9.28e-077105329372668
Pubmed

A ciliopathy complex builds distal appendages to initiate ciliogenesis.

OFD1 TUBG2 TUBG1

1.48e-068105334241634
Pubmed

A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development.

TUBG2 INHBB TUBG1

1.48e-068105315958512
Pubmed

Rack1 regulates cellular patterning and polarity in the mouse cochlea.

TUBG2 TUBG1 GPSM2

1.48e-068105336252648
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LRRC8E TANC2 OFD1 KALRN FNTB ITGA5 TUBG1 TBC1D24 ITPR2 FAM20C CHD5 MARK4 PDZD8 BCL2L13

6.14e-0611051051435748872
Pubmed

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

TUBG2 TUBG1

9.03e-062105228119396
Pubmed

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS2 genes independently contribute to the production and function of platelet dense granules, melanosomes, and lysosomes.

AP3B1 HPS1

9.03e-062105211861280
Pubmed

Susceptibility of Hermansky-Pudlak mice to bleomycin-induced type II cell apoptosis and fibrosis.

AP3B1 HPS1

9.03e-062105217363777
Pubmed

The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors.

FLT3 PDGFRB

9.03e-062105217229632
Pubmed

The T complex distorter 2 candidate gene, Dnahc8, encodes at least two testis-specific axonemal dynein heavy chains that differ extensively at their amino and carboxyl termini.

FGD2 DNAH8

9.03e-062105212297094
Pubmed

Unveiling a novel serpinB2-tripeptidyl peptidase II signaling axis during senescence.

TPP2 SERPINB2

9.03e-062105235466366
Pubmed

Defective surfactant secretion in a mouse model of Hermansky-Pudlak syndrome.

AP3B1 HPS1

9.03e-062105215790974
Pubmed

Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium.

PDGFRB MCAM

9.03e-062105217872908
Pubmed

MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.

TUBG2 TUBG1

9.03e-062105217442887
Pubmed

Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation.

ZFYVE27 PDZD8

9.03e-062105232917905
Pubmed

Overexpression of γ-tubulin in non-small cell lung cancer.

TUBG2 TUBG1

9.03e-062105222806905
Pubmed

The Ap3b1 gene regulates the ocular melanosome biogenesis and tyrosinase distribution differently from the Hps1 gene.

AP3B1 HPS1

9.03e-062105225160823
Pubmed

Mutation and methylation analysis of the chromodomain-helicase-DNA binding 5 gene in ovarian cancer.

KALRN CHD5

9.03e-062105218953434
Pubmed

CD146 is essential for PDGFRβ-induced pericyte recruitment.

PDGFRB MCAM

9.03e-062105229039032
Pubmed

Different functions of biogenesis of lysosomal organelles complex 3 subunit 1 (Hps1) and adaptor-related protein complex 3, beta 1 subunit (Ap3b1) genes on spermatogenesis and male fertility.

AP3B1 HPS1

9.03e-062105230786955
Pubmed

Aberrant lung structure, composition, and function in a murine model of Hermansky-Pudlak syndrome.

AP3B1 HPS1

9.03e-062105212777251
Pubmed

Gene knockout analysis of two gamma-tubulin isoforms in mice.

TUBG2 TUBG1

9.03e-062105215893303
Pubmed

Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.

TUBG2 TUBG1

9.03e-062105217287496
Pubmed

Lung-restricted macrophage activation in the pearl mouse model of Hermansky-Pudlak syndrome.

AP3B1 HPS1

9.03e-062105216547274
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH2 DNAH8

9.50e-061410539373155
Pubmed

Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain.

TUBG2 TUBG1 GPSM2

1.46e-0516105319332887
Pubmed

Huntingtin regulates mammary stem cell division and differentiation.

TUBG2 TUBG1 GPSM2

2.11e-0518105324749073
Pubmed

Cep120 is essential for kidney stromal progenitor cell growth and differentiation.

PDGFRB TUBG2 TUBG1

2.50e-0519105338177914
Pubmed

FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue.

TUBG2 TUBG1 AKAP9

2.50e-0519105334348145
Pubmed

The gamma-tubulin gene family in humans.

TUBG2 TUBG1

2.70e-053105210903841
Pubmed

Disorders of vesicles of lysosomal lineage: the Hermansky-Pudlak syndromes.

AP3B1 HPS1

2.70e-053105212125811
Pubmed

Potentiation of antileukemic therapies by the dual PI3K/PDK-1 inhibitor, BAG956: effects on BCR-ABL- and mutant FLT3-expressing cells.

FLT3 PDPK2P

2.70e-053105218184863
Pubmed

Pattern of segmental recombination in the distal inversion of mouse t haplotypes.

FGD2 DNAH8

2.70e-053105212226709
Pubmed

Lysosomal dysfunctions associated with mutations at mouse pigment genes.

AP3B1 HPS1

2.70e-0531052115747
Pubmed

Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.

TUBG2 TUBG1

2.70e-053105227015882
Pubmed

Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin.

TUBG2 TUBG1

2.70e-05310529566969
Pubmed

Identification of novel FLT3 kinase inhibitors.

FLT3 PDGFRB

2.70e-053105223567961
Pubmed

Matrix metalloproteinase activity in the lung is increased in Hermansky-Pudlak syndrome.

AP3B1 HPS1

2.70e-053105231272455
Pubmed

The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage.

TUBG2 TUBG1

2.70e-053105226021315
Pubmed

DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction.

TUBG2 TUBG1 GPSM2

3.95e-0522105333899739
Pubmed

PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division.

TUBG2 PDPK2P TUBG1

4.53e-0523105331504280
Pubmed

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

OFD1 TUBG2 TUBG1 AKAP9

4.89e-0566105412221128
Pubmed

Defining the membrane proteome of NK cells.

OFD1 PDGFRB LSG1 POLD1 FIS1 AP3B1 CTSA POLR3A ITPR2 CHD5 BYSL PDZD8 ABHD13

5.17e-0511681051319946888
Pubmed

Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes.

AP3B1 HPS1

5.40e-054105229190429
Pubmed

MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.

AP3B1 HPS1

5.40e-054105226719147
Pubmed

Loss of Necdin impairs myosin activation and delays cell polarization.

TUBG2 TUBG1

5.40e-054105220665884
Pubmed

Migratory properties of pulmonary dendritic cells are determined by their developmental lineage.

FLT3 CCR7

5.40e-054105223168837
Pubmed

Cilia organize ependymal planar polarity.

TUBG2 TUBG1

5.40e-054105220164345
Pubmed

The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.

AP3B1 HPS1

5.40e-054105223043085
Pubmed

CCR7 Is Important for Mesangial Cell Physiology and Repair.

PDGFRB CCR7

5.40e-054105229077526
Pubmed

Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia.

FLT3 PDGFRB

5.40e-054105228751768
Pubmed

Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells.

TUBG2 TUBG1

5.40e-054105216798874
Pubmed

Ofd1 controls dorso-ventral patterning and axoneme elongation during embryonic brain development.

OFD1 TUBG2 TUBG1

6.61e-0526105323300826
Pubmed

Conditional knockout mice for the distal appendage protein CEP164 reveal its essential roles in airway multiciliated cell differentiation.

TUBG2 TUBG1

8.97e-055105229244804
Pubmed

Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia.

TUBG2 TUBG1

8.97e-055105231390572
Pubmed

Progenitor cell defect correctable by bone marrow transplantation in five independent mouse models of platelet storage pool deficiency.

AP3B1 HPS1

8.97e-05510523516713
Pubmed

A two-kinesin mechanism controls neurogenesis in the developing brain.

TUBG2 TUBG1

8.97e-055105238040957
Pubmed

Regulation of microtubule formation in activated mast cells by complexes of gamma-tubulin with Fyn and Syk kinases.

TUBG2 TUBG1

8.97e-055105216751367
Pubmed

A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos.

TUBG2 TUBG1

8.97e-055105215680357
Pubmed

Mesenchymal stem cell migration is regulated by fibronectin through α5β1-integrin-mediated activation of PDGFR-β and potentiation of growth factor signals.

PDGFRB ITGA5

8.97e-055105221429937
Pubmed

SCFFBXW7 regulates G2-M progression through control of CCNL1 ubiquitination.

CUL1 CCNL1

8.97e-055105236278408
Pubmed

Exome sequencing identifies SLC24A5 as a candidate gene for nonsyndromic oculocutaneous albinism.

AP3B1 HPS1

8.97e-055105223364476
Pubmed

Analysis of Ellis van Creveld syndrome gene products: implications for cardiovascular development and disease.

TUBG2 TUBG1

8.97e-055105219251731
Pubmed

The essential role of centrosomal NDE1 in human cerebral cortex neurogenesis.

TUBG2 TUBG1

8.97e-055105221529752
Pubmed

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.

TUBG2 TUBG1

8.97e-055105218729223
Pubmed

Abnormal vesicular trafficking in mouse models of Hermansky-Pudlak syndrome.

AP3B1 HPS1

8.97e-055105211041359
Pubmed

The centrosomal E3 ubiquitin ligase FBXO31-SCF regulates neuronal morphogenesis and migration.

CUL1 TUBG1

8.97e-055105223469015
Pubmed

WDR62 is associated with the spindle pole and is mutated in human microcephaly.

TUBG2 TUBG1

8.97e-055105220890279
Pubmed

Speriolin is a novel human and mouse sperm centrosome protein.

TUBG2 TUBG1

8.97e-055105220542897
Pubmed

Novel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomalies.

TUBG2 TUBG1

8.97e-055105225877302
Pubmed

HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes.

TUBG2 TUBG1

8.97e-055105214767062
Pubmed

Centrosome-targeting region of CG-NAP causes centrosome amplification by recruiting cyclin E-cdk2 complex.

TUBG1 AKAP9

8.97e-055105215670215
Pubmed

Inflammation induces two types of inflammatory dendritic cells in inflamed lymph nodes.

FLT3 CCR7

8.97e-055105229546878
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

OFD1 LSG1 ARHGEF12 POLR3A UPF2 SNX6

1.18e-04251105629778605
Pubmed

The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP.

TUBG2 TUBG1

1.34e-046105238546045
Pubmed

Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor.

TUBG2 TUBG1

1.34e-046105230970247
Pubmed

Expression Analyses of Cep152, a Responsible Gene Product for Autosomal Recessive Primary Microcephaly, during Mouse Brain Development.

TUBG2 TUBG1

1.34e-046105235259752
Pubmed

Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells.

PDGFRB PIEZO2

1.34e-046105235273307
Pubmed

DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis.

TUBG2 TUBG1

1.34e-046105222842144
Pubmed

Cytoplasmic Cl- couples membrane remodeling to epithelial morphogenesis.

TUBG2 TUBG1

1.34e-046105229229864
Pubmed

Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton.

TUBG2 TUBG1

1.34e-046105210840040
Pubmed

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors.

TUBG2 TUBG1

1.34e-046105236334595
Pubmed

A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity.

TUBG2 TUBG1

1.34e-046105211237715
Pubmed

A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.

ACACB AP3B1 ITPR2 AKAP9 MORF4L2 CCNL1 BYSL MOV10

1.48e-04503105836217030
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

CUL1 TMEM126A LSG1 FIS1 POLR3A ITPR2 VPS13D AKAP9 UPF2 SNX6 BYSL PDZD8 BCL2L13 MOV10

1.65e-0414961051432877691
Pubmed

A proteome-scale map of the SARS-CoV-2-human contactome.

KALRN ANKRD36B AKAP9 MORF4L2 BYSL

1.86e-04173105536217029
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD3

1.88e-047105221205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD3

1.88e-047105218949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD3

1.88e-047105225187515
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD3

1.88e-04710529037092
Pubmed

HIV-1 Vpr hijacks EDD-DYRK2-DDB1DCAF1 to disrupt centrosome homeostasis.

TUBG2 TUBG1

1.88e-047105229724823
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD3

1.88e-04710528603673
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD3

1.88e-047105215710750
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD3

1.88e-047105226632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD3

1.88e-047105224403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD3

1.88e-047105223818861
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD3

1.88e-047105211353387
GeneFamilyDyneins, axonemal

DNAH10 DNAH2 DNAH8

3.48e-0517693536
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 TANC2 FIS1 RGPD3 GPSM2

7.75e-05115695769
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

ZFYVE27 FGD2 PLEKHF1

2.21e-043169381
GeneFamilyBeta 4-glycosyltransferases

B4GALT6 CHSY3

1.88e-0317692425
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

FGD2 KALRN ARHGEF12

2.05e-0366693722
GeneFamilyADAM metallopeptidase domain containing|CD molecules

FLT3 PDGFRB MCAM ITGA5 CCR7 ENPEP

3.89e-03394696471
GeneFamilyTubulins

TUBG2 TUBG1

4.40e-0326692778
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

DNAH10 DNAH2 CCDC175 VWA3B SPAG17 PPP1R42

4.84e-06185104630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH10 DNAH2 CCDC175 VWA3B SPAG17 PPP1R42

5.47e-061891046a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

DNAH10 DNAH2 CCDC175 VWA3B SPAG17 PPP1R42

5.47e-06189104627329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH2 CCDC175 AKAP9 VWA3B SPAG17

6.94e-06197104674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

INHBB ANKRD36B VPS13D AKAP9 ANKRD36 SPAG17

7.35e-06199104661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH10 DNAH2 CCDC175 VWA3B SPAG17 PPP1R42

7.56e-062001046926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DNAH10 DNAH2 CCDC175 VWA3B SPAG17 PPP1R42

7.56e-06200104606ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCellTracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN PDGFRB MCAM CHSY3 ENPEP FRMD3

7.56e-0620010469d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCellTracheal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN PDGFRB MCAM CHSY3 ENPEP FRMD3

7.56e-06200104678cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCellSevere-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DNAH10 HUNK RGPD3 PCID2 FRMD3

2.99e-05153104544572f87d403e314050ab935d2cd676c33d9c287
ToppCellSevere-B_naive-5|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DNAH10 HUNK RGPD3 PCID2 FRMD3

3.38e-051571045a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

KALRN PDGFRB MCAM ENPEP FRMD3

3.70e-05160104529c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 FGD2 SLC27A6 MYO9A CRPPA

3.70e-051601045a494001b1f6dec33624f98fa3c24bad6988d0425
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

DNAH2 CCDC175 CCR7 SPAG17 RIC3

3.92e-05162104591cc14aec8d580cf97a1929bc1acb00fcbcdb57a
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tnaive/CM_CD8|GI_small-bowel / Manually curated celltypes from each tissue

ACACB ITPR2 CCR7 PCID2 MOV10

4.67e-051681045c51244b4bdbfd961e2725306aa9cb25dd66d58bd
ToppCelldroplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 DNAH2 CCRL2 CCR7 KYNU

5.51e-0517410459019011eb8d9b7a95804fc11434f0fd42418103a
ToppCelldroplet-Tongue-Unstain-18m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 DNAH2 CCRL2 CCR7 KYNU

5.51e-051741045deafbd0c2523afe09cc42f8c7b33945f3f5c00b4
ToppCelldroplet-Tongue-Unstain-18m-Myeloid|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 DNAH2 CCRL2 CCR7 KYNU

5.51e-051741045f2eb0199f59e1e2f46da344c05289876bd254fa3
ToppCelldroplet-Tongue-nan-3m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 DNAH2 CCRL2 B4GALT6 CCR7

5.98e-0517710458f4b2f21091d981c12000489054198127098f62c
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 CCDC175 VWA3B SPAG17 PPP1R42

5.98e-051771045c38138fb5ad9766c2d240811210c854338cd612e
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

6.14e-051781045255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 CCDC175 VWA3B SPAG17 PPP1R42

6.14e-051781045de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

6.30e-0517910455e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 ACACB OFD1 KALRN CHD5

6.47e-0518010457368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

KALRN PDGFRB MCAM ENPEP FRMD3

6.64e-0518110458dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACACB PIK3C2G ATP6V0D2 MAPK4 FRMD3

6.64e-051811045e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

KALRN PDGFRB MCAM ENPEP FRMD3

6.82e-0518210452075efeae633550fb2eb026d0dfd741c8252482e
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

6.82e-0518210457ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

6.82e-051821045fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCelldroplet-Tongue-nan-24m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT3 DNAH2 CCRL2 CCR7 KYNU

6.82e-0518210450f06309318c064f0ebdb12a46226b90032290137
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

KALRN PDGFRB MCAM SLC35F4 ENPEP

7.00e-051831045818fd886e0188091310825f9145fa53328f2c979
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

KALRN PDGFRB MCAM ENPEP FRMD3

7.00e-051831045e3835db4795362b0442d5893baf2a78efcc20428
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

KALRN PDGFRB VPS13D ENPEP FRMD3

7.00e-051831045273db6a3b00a93ca852498471187b642b5368185
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FLT3 INHBB MCAM PIEZO2 FRMD3

7.00e-051831045439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

KALRN PDGFRB MCAM SLC35F4 ENPEP

7.00e-051831045cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 KALRN PIEZO2 PIK3C2G SPAG17

7.18e-0518410452cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 KALRN PIEZO2 PIK3C2G SPAG17

7.18e-051841045ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 KALRN PIEZO2 PIK3C2G SPAG17

7.18e-0518410452b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.18e-0518410455daff849625f2f41d56615569c0ed59cd733b34c
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ACACB ITPR2 FAM20C AFM KLB

7.37e-0518510451d874608aa2062024323512f68889219471b2f00
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.37e-0518510455e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.37e-0518510450998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.37e-0518510453e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.37e-05185104518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

KALRN PDGFRB MCAM ENPEP FRMD3

7.37e-051851045acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.56e-051861045f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.56e-05186104576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.56e-05186104585787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellRV-07._Pericyte|RV / Chamber and Cluster_Paper

KALRN PDGFRB MCAM ENPEP FRMD3

7.56e-051861045c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

KALRN PDGFRB MCAM ENPEP FRMD3

7.75e-051871045dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.75e-0518710459e10ed56090d82589bc457788282f664b70ace4b
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.75e-051871045bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.95e-05188104561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.95e-051881045803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.95e-05188104534b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.95e-0518810452b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

7.95e-0518810459a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FLT3 FGD2 CCRL2 CCR7 KYNU

8.15e-05189104535380ca9409206e82528bde4f3795057b015278a
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.15e-05189104568a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FLT3 FGD2 CCRL2 CCR7 KYNU

8.15e-05189104531c8bc506ad69f2ed5676bd7e5319bad1075c8d8
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.15e-051891045a3cd4c2da4feb9bdcd8957f3e344d095da1367b8
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.15e-051891045b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC27A6 PDGFRB PIEZO2 GPSM2 FRMD3

8.15e-0518910452a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellCiliated|World / shred by cell class for parenchyma

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.15e-051891045711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellcellseq2-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.15e-05189104593b1026bb1ba759e5704561c9a5de14a30c08894
ToppCellCF-Lymphoid-B_cell|CF / Disease state, Lineage and Cell class

FGD2 PUM3 CCR7 DNAH8 RIC3

8.35e-051901045374d8fd63c733178acab07682ed1519693efab45
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.35e-051901045169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.35e-0519010450cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.35e-0519010457031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.35e-05190104517829f4de31b3d9e4d71ba4817d18842aa699773
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.35e-051901045426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-0519110457b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-0519110452a8e6d560907e71e9f6e190ca0667da804e25641
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-05191104546c9d4d10c66c0fae1fa351924091b69ea2f38d4
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-0519110459f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-05191104528caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellMild_COVID-19-Epithelial-Ciliated|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045995e76bbf07674d95b8ef09e078cf6410af27a09
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-0519110455129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045a37f20172b85566b9039254a89680e37fd503fd5
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellBAL-Mild-Epithelial-Epithelial-Ciliated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-0519110452d36e08c5629cf73b6dd02cd173cafb52e8a3a7d
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-05191104515b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class (2021.01.30)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045b78547dae8328244a47c83346447bdd787efbcae
ToppCellwk_15-18-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045e81cd65dbf0ef1c2ab7088f73ce605d456dd3a7a
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.56e-051911045cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.77e-051921045097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellmulticiliated|World / shred by cell class for turbinate

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.77e-0519210450f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.99e-051931045aa3acc7571405169efb656d214f3a8cbf988362e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

8.99e-051931045ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellwk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

9.21e-051941045756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell3'-Distal_airway|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

9.21e-051941045e9ff4398e880d13894e52c0ba9cf19a7662c248b
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

9.21e-0519410451ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

9.21e-051941045b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAH10 DNAH2 VWA3B SPAG17 PPP1R42

9.44e-051951045d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DNAH2 CCRL2 UPF2 SERPINB2 ATP6V0D2

9.44e-051951045d53585715c7f5827c4f5a6db11cb31857ee9d4f0
Diseasecomplex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)

TUBG2 TUBG1

1.14e-0521002DOID:0090138 (implicated_via_orthology)
DiseaseColorectal Carcinoma

KALRN POLD1 NDST3 AKAP9 CHD5 PAN2 SPAG17 DNAH8 EDRF1 RIC3

1.38e-0470210010C0009402
DiseaseHermanski-Pudlak Syndrome

AP3B1 HPS1

5.03e-04101002C0079504
DiseaseHermansky-Pudlak syndrome

AP3B1 HPS1

5.03e-04101002cv:C0079504
Diseasevesicular integral-membrane protein VIP36 measurement

KALRN NLK

5.03e-04101002EFO_0022012
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

AP3B1 HPS1

1.16e-03151002DOID:2223 (implicated_via_orthology)
DiseaseMultiple congenital anomalies

POLD1 KYNU

1.50e-03171002C0000772
Diseasesusceptibility to mononucleosis measurement

CUL1 DNAH2 DNAH8

1.68e-03691003EFO_0008403
Diseaseaspartate measurement

NDST3 ENPEP

2.99e-03241002EFO_0010462

Protein segments in the cluster

PeptideGeneStartEntry
LKVNLLLVDYRGYGK

ABHD13

141

Q7L211
KYVVLSYLGLLSQEK

BCL2L13

16

Q9BXK5
FRKALIYQKKYLLLL

AKAP9

3711

Q99996
IYQKKYLLLLLGGFQ

AKAP9

3716

Q99996
YKGLKRVENIYLLNL

CCRL2

66

O00421
RVLNSYKIDYKLLLT

CHD5

861

Q8TDI0
NLGKDGLKYHYLIRL

AFM

421

P43652
NGLVVLTYIYFKRLK

CCR7

76

P32248
LQYLQELLALRKKYL

C13orf42

86

A0A1B0GVH6
LHGNLEKLKYLLLTY

ANKRD36

41

A6QL64
GNLEKLKYLLLTYYD

ANKRD36B

31

Q8N2N9
YDALRDNSLLYKKRL

AADACL3

346

Q5VUY0
LRLYTRKKPNYELLE

CCNL1

286

Q9UK58
RLTKYPLLLDNIAKY

ARHGEF12

936

Q9NZN5
TKLLTQYILNLGKYD

AP3B1

551

O00203
GKYILIIYENILKYI

NDST3

126

O95803
LGVVRIYNRKAKYLL

RAD21L1

61

Q9H4I0
DAYLRKLGLYRKLVA

OTUD4

26

Q01804
TYDRKLKNELLKYQL

OFD1

341

O75665
LLTLIRKYDFHLKYL

PIK3C2G

406

O75747
SIVNDKYGRKVLLYL

PUM3

431

Q15397
KYGRKVLLYLLSPRD

PUM3

436

Q15397
RKILLNRYFKGDYSI

ITPR2

1696

Q14571
VKERNILLYGLLISY

CRPPA

401

A4D126
ELIYGGVKYILKVAR

ACACB

816

O00763
RTALQLYRKYLELSK

PAN2

1141

Q504Q3
ASEYYKKTLLLARQL

GPSM2

261

P81274
SARYILKDYVSGKLL

LSG1

531

Q9H089
ILQYGLESLKRKTSY

IL31RA

476

Q8NI17
LQKYGRALRYIKLAL

EDRF1

706

Q3B7T1
AKLFMYQLLRGLKYI

MAPK4

126

P31152
NLYKGAVLYLLRGRK

HERC3

561

Q15034
YITAALKLLEKLYKV

HERC3

586

Q15034
YLKLLPYVLEKGSRR

INHBB

181

P09529
LSNGYISDVKLLYKI

F13B

96

P05160
EYEKALKYVRGLLQT

FIS1

86

Q9Y3D6
RKLTVGDVYKLLLRY

PARG

921

Q86W56
LKLIKQAGDRVLVYY

PDZD8

431

Q8NEN9
TRKELNLLQKLYGLY

DNAH8

1271

Q96JB1
TLKYSYKEVGLLLLY

KCNS2

321

Q9ULS6
YQLLLKDFLRYSEKA

KALRN

2066

O60229
LLLGYLHDFLKYLAK

MORF4L2

251

Q15014
KLRSLEQLYLSYNKL

LRRC8E

651

Q6NSJ5
TVLYSKYGGKDLLLL

LRIT3

516

Q3SXY7
LDYKVALNLTKYLKR

ENPEP

671

Q07075
SLRGEVLKLYKNLLY

ETFRF1

6

Q6IPR1
VLKLYKNLLYLGRDY

ETFRF1

11

Q6IPR1
GLSYAKNGELLKYIR

PDPK2P

131

Q6A1A2
GIFLYILYILFKLSK

RIC3

106

Q7Z5B4
VKVFLYQILRGLKYL

NLK

241

Q9UBE8
YLKLLSSQKYQILLY

CTSA

381

P10619
LYIIQEGRILYKGKS

DIO1

216

P49895
LIYILYKLGFFKRSL

ITGA5

1016

P08648
TYRNLFKKVYLLLKT

PCID2

321

Q5JVF3
YLRKTRGYLIKILDD

RGPD3

711

A6NKT7
YGDLLNYLRSKREKF

FLT3

696

P36888
PLKIKEELTRYLLYL

FRMD3

116

A2A2Y4
ILDKSYYLGLLRSKI

IFT74

91

Q96LB3
DKYRQLPLEKVYSLL

KLHL22

186

Q53GT1
GNKYITLKDYRILLK

C5orf60

86

A6NFR6
KLLRYSKERQYIDGL

B4GALT6

336

Q9UBX8
KLYYLLETLPNSIKR

CCDC175

101

P0C221
LLLENKKLKEYILYL

CCDC175

656

P0C221
FILLLKALLLSSYGK

ARV1

176

Q9H2C2
STYLRLQLLAKEEYK

FAM20C

506

Q8IXL6
LELYKRLKEFLKNYL

CUL1

86

Q13616
AIYFLLNKKLERYLS

HUNK

376

P57058
YIRKKTRLLVVLQGY

DNAAF9

816

Q5TEA3
LALLEEKLRYSNEKY

FAAH2

411

Q6GMR7
KYNEVTATYLLLGRK

MARK4

356

Q96L34
RYELLLKEYIQKLPA

FGD2

251

Q7Z6J4
IINREKLLQYLYSLK

FNTB

171

P49356
YLGKYLQEVLKAYLI

KLB

906

Q86Z14
SEGDLRRKLYVLKYL

HPS1

101

Q92902
LKLLLEKGYLYDRGK

DNAH10

2541

Q8IVF4
KYLELLSGYKKLLGE

DNAH2

2981

Q9P225
YLLISKKRYAGLLFS

POLD1

801

P28340
LGVNILHLSYLLYKK

BVES

101

Q8NE79
LDKKYALPYRVLDAL

BYSL

346

Q13895
LLLERLLGEGYKKKY

PDGFRB

956

P09619
LQEYVRKLLYKDLSK

UPF2

771

Q9HAU5
YLREKLNIGYIEDLK

SERPINB2

236

P05120
VLAVLGAVLYFLYKK

MCAM

571

P43121
ILVYGSIVLNKRKYR

PLEKHF1

61

Q96S99
YLRKTRGYLIKILDD

RGPD4

711

Q7Z3J3
LLQSKVGLLTYYVKL

BPY2

61

O14599
TLLFVITLYKLYKKG

TMCO2

81

Q7Z6W1
AYLGSEQYKLLIKAL

TMEM126A

171

Q9H061
SLLERLLTYNSLYKK

MOV10

701

Q9HCE1
RELYLKELRTQKLYT

FAM183A

21

A6NL82
RSLKKLEKLYLGGNY

PPP1R42

91

Q7Z4L9
KKLYLSSNLIQKIYR

SLITRK3

411

O94933
LDYLKRPGLTYLQKR

POLR3A

126

O14802
YLKLTFDLIEKGYLV

TANC2

656

Q9HCD6
LTNYLYLLALKKLTA

SLC35F4

261

A4IF30
RLQVSLKDYINYILK

SPAG17

1781

Q6Q759
KSLKALKLNYLDLYL

AKR1E2

86

Q96JD6
EYILDLLLLYKRHKG

CHSY3

536

Q70JA7
GYKVLYRVALAILKF

TBC1D24

236

Q9ULP9
TIKLLKGDLAYNYRG

TMX3

101

Q96JJ7
SYLLERLNDRYPKKL

TUBG1

151

P23258
KKEGYVLYDLIQLLA

PIEZO2

2011

Q9H5I5
QYSLKLEKGDYTIRL

TPP2

876

P29144
LKYYLRESQAAKDLL

SNX6

296

Q9UNH7
VLSYKRLEIYLEPLK

ZFYVE27

41

Q5T4F4
SYLLERLNDRYPKKL

TUBG2

151

Q9NRH3
KYGLKAQKLSLYDVL

VWA3B

396

Q502W6
NLKKSYVLLTRELYD

SLC27A6

596

Q9Y2P4
LNIELLRNKLYKSYL

ATP6V0D2

176

Q8N8Y2
LYKYKLIRGLLENNL

VPS13D

2241

Q5THJ4
LKLRLVSGRQYYLAL

GARIN5B

121

Q8N5Q1
ALRKKSVLLTGYLEY

KYNU

356

Q16719
LGAYVEKYLLEKSRL

MYO9A

311

B2RTY4