Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDEAD/H-box RNA helicase binding

SMAD1 SMAD3 SMAD5

3.72e-0591553GO:0017151
GeneOntologyMolecularFunctionG-protein beta/gamma-subunit complex binding

GNAI1 GNAI3 GNAT1 GNAT2

3.89e-05251554GO:0031683
GeneOntologyMolecularFunctioncomplement component C3b receptor activity

CR1 CR1L

5.99e-0521552GO:0004877
GeneOntologyMolecularFunctioncomplement component C4b receptor activity

CR1 CR1L

5.99e-0521552GO:0001861
GeneOntologyMolecularFunctioncomplement component C4b binding

CR1 CR1L

1.79e-0431552GO:0001855
GeneOntologyMolecularFunctionI-SMAD binding

SMAD1 SMAD3 SMAD5

2.88e-04171553GO:0070411
GeneOntologyMolecularFunctionhistone H4K20 demethylase activity

PHF8 PHF2

3.56e-0441552GO:0035575
GeneOntologyMolecularFunctionG protein-coupled serotonin receptor binding

GNAI1 GNAI3

5.90e-0451552GO:0031821
GeneOntologyMolecularFunctionhistone H4 demethylase activity

PHF8 PHF2

5.90e-0451552GO:0141058
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

PLXNA3 MRC1 IL12RB2 GPR65 ROR1 GRID2 PTPRU GRM3 CR1 CR1L CHRNA2 TLR10 CD3E TNFRSF8 OR6C4 TLR5 MTNR1B ADGRE4P TRPV4 CCR3 GNAT2 IL17RD

7.77e-04135315522GO:0004888
GeneOntologyBiologicalProcessnegative regulation of complement activation, classical pathway

CD46 CR1 CR1L

2.22e-0581543GO:0045959
GeneOntologyBiologicalProcessregulation of complement activation, classical pathway

CD46 CR1 CR1L

4.71e-05101543GO:0030450
GeneOntologyBiologicalProcessbackground adaptation

GNAT1 GNAT2

5.54e-0521542GO:0120302
GeneOntologyBiologicalProcessnegative regulation of rDNA heterochromatin formation

PHF8 PHF2

5.54e-0521542GO:0061188
GeneOntologyCellularComponentheteromeric SMAD protein complex

SMAD1 SMAD3 SMAD5

2.44e-0581613GO:0071144
GeneOntologyCellularComponentSMAD protein complex

SMAD1 SMAD3 SMAD5

5.17e-05101613GO:0071141
GeneOntologyCellularComponentextrinsic component of cytoplasmic side of plasma membrane

CARMIL2 GNAI1 GNAI3 GNAT1 GNAT2

7.08e-05561615GO:0031234
GeneOntologyCellularComponentside of membrane

IL12RB2 CARMIL2 RASA3 ANO1 MIEN1 CR1 CR1L TFRC CD3E EFNA5 MUC17 CCR3 GNAI1 GNAI3 GNAT1 GNAT2 MSLN CD276

1.45e-0487516118GO:0098552
GeneOntologyCellularComponentheterotrimeric G-protein complex

GNAI1 GNAI3 GNAT1 GNAT2

1.47e-04351614GO:0005834
GeneOntologyCellularComponentGTPase complex

GNAI1 GNAI3 GNAT1 GNAT2

2.75e-04411614GO:1905360
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

CARMIL2 RASA3 MIEN1 GNAI1 GNAI3 GNAT1 GNAT2

5.89e-041851617GO:0009898
GeneOntologyCellularComponentextrinsic component of plasma membrane

CARMIL2 APC2 GNAI1 GNAI3 GNAT1 GNAT2

6.81e-041371616GO:0019897
GeneOntologyCellularComponentcell surface

HYAL4 MRC1 IL12RB2 ROR1 ANO1 CD46 ADAMTS13 CR1 CR1L TFRC CD3E EFNA5 MUC17 MRC2 ADGRE4P TRPV4 CCR3 MSLN CD276

9.35e-04111116119GO:0009986
DomainGprotein_alpha_I

GNAI1 GNAI3 GNAT1 GNAT2

2.95e-0781534IPR001408
DomainCUB

ADAMTS13 BMP1 MEGF8 C1R TNFAIP6 SEZ6

4.58e-06531536PS01180
DomainCUB_dom

ADAMTS13 BMP1 MEGF8 C1R TNFAIP6 SEZ6

7.04e-06571536IPR000859
DomainGproteinA_insert

GNAI1 GNAI3 GNAT1 GNAT2

7.30e-06161534IPR011025
Domain-

GNAI1 GNAI3 GNAT1 GNAT2

7.30e-061615341.10.400.10
DomainG-alpha

GNAI1 GNAI3 GNAT1 GNAT2

7.30e-06161534PF00503
DomainG_alpha

GNAI1 GNAI3 GNAT1 GNAT2

7.30e-06161534SM00275
DomainGprotein_alpha_su

GNAI1 GNAI3 GNAT1 GNAT2

9.48e-06171534IPR001019
DomainEGF

HYAL4 ZAN MEP1A BMP1 TENM4 MEGF8 MUC17 ADGRE4P TENM1 C1R

2.45e-0523515310SM00181
DomainEGF_3

ZAN SSPOP MEP1A BMP1 TENM4 MEGF8 MUC17 ADGRE4P TENM1 C1R

2.45e-0523515310PS50026
DomainDWB

SMAD1 SMAD3 SMAD5

2.93e-0581533SM00524
DomainMH2

SMAD1 SMAD3 SMAD5

2.93e-0581533PS51076
DomainMH1

SMAD1 SMAD3 SMAD5

2.93e-0581533PS51075
Domain-

SMAD1 SMAD3 SMAD5

2.93e-05815333.90.520.10
DomainMAD_homology_MH1

SMAD1 SMAD3 SMAD5

2.93e-0581533IPR013019
DomainDwarfin

SMAD1 SMAD3 SMAD5

2.93e-0581533IPR013790
DomainMH2

SMAD1 SMAD3 SMAD5

2.93e-0581533PF03166
DomainSMAD_dom_Dwarfin-type

SMAD1 SMAD3 SMAD5

2.93e-0581533IPR001132
DomainEGF_1

HYAL4 ZAN SSPOP MEP1A BMP1 TENM4 MEGF8 MUC17 TENM1 C1R

4.90e-0525515310PS00022
DomainCUB

BMP1 MEGF8 C1R TNFAIP6 SEZ6

4.93e-05491535PF00431
DomainCUB

BMP1 MEGF8 C1R TNFAIP6 SEZ6

5.44e-05501535SM00042
Domain-

BMP1 MEGF8 C1R TNFAIP6 SEZ6

6.58e-055215352.60.120.290
DomainSushi

CD46 CR1 CR1L C1R SEZ6

6.58e-05521535PF00084
DomainEGF_2

HYAL4 ZAN SSPOP MEP1A BMP1 TENM4 MEGF8 MUC17 TENM1 C1R

6.76e-0526515310PS01186
DomainCCP

CD46 CR1 CR1L C1R SEZ6

7.91e-05541535SM00032
DomainSUSHI

CD46 CR1 CR1L C1R SEZ6

9.43e-05561535PS50923
DomainSushi_SCR_CCP_dom

CD46 CR1 CR1L C1R SEZ6

1.03e-04571535IPR000436
DomainMAD_homology1_Dwarfin-type

SMAD1 SMAD3 SMAD5

1.12e-04121533IPR003619
DomainDWA

SMAD1 SMAD3 SMAD5

1.12e-04121533SM00523
DomainMH1

SMAD1 SMAD3 SMAD5

1.12e-04121533PF03165
DomainEGF-like_dom

ZAN MEP1A BMP1 TENM4 MEGF8 MUC17 ADGRE4P TENM1 C1R

2.17e-042491539IPR000742
DomainMAM_1

ZAN PTPRU MEP1A

2.79e-04161533PS00740
DomainSMAD_dom-like

SMAD1 SMAD3 SMAD5

2.79e-04161533IPR017855
Domain-

SMAD1 SMAD3 SMAD5

2.79e-041615332.60.200.10
DomainMAM

ZAN PTPRU MEP1A

3.37e-04171533SM00137
DomainTox-GHH_dom

TENM4 TENM1

3.96e-0441532IPR028916
DomainMABP

DENND4A DENND4B

3.96e-0441532PS51498
DomainTox-GHH

TENM4 TENM1

3.96e-0441532PF15636
DomainMABP

DENND4A DENND4B

3.96e-0441532IPR023341
DomainTen_N

TENM4 TENM1

3.96e-0441532IPR009471
DomainTen_N

TENM4 TENM1

3.96e-0441532PF06484
DomainTENEURIN_N

TENM4 TENM1

3.96e-0441532PS51361
DomainMAM

ZAN PTPRU MEP1A

4.02e-04181533PF00629
DomainMAM_dom

ZAN PTPRU MEP1A

4.02e-04181533IPR000998
DomainMAM_2

ZAN PTPRU MEP1A

4.02e-04181533PS50060
DomainYD

TENM4 TENM1

6.56e-0451532IPR006530
DomainPeptidase_M12A

MEP1A BMP1

9.79e-0461532IPR001506
DomainAstacin

MEP1A BMP1

9.79e-0461532PF01400
DomainTIR_dom

TLR10 TLR5 IL17RD

1.09e-03251533IPR000157
DomainEGF-like_CS

ZAN MEP1A BMP1 TENM4 MEGF8 MUC17 TENM1 C1R

1.42e-032611538IPR013032
DomainPPR

DENND4A DENND4B

1.81e-0381532PS51375
DomainKringle-like

MRC1 ROR1 MRC2

2.25e-03321533IPR013806
DomainPeptidase_S8_His-AS

TPP2 MBTPS1

2.31e-0391532IPR022398
DomainPeptidase_S8_Ser-AS

TPP2 MBTPS1

2.31e-0391532IPR023828
DomainPeptidase_S8_subtilisin-rel

TPP2 MBTPS1

2.87e-03101532IPR015500
DomainSUBTILASE_ASP

TPP2 MBTPS1

2.87e-03101532PS00136
DomainSUBTILASE_HIS

TPP2 MBTPS1

2.87e-03101532PS00137
DomainSUBTILASE_SER

TPP2 MBTPS1

2.87e-03101532PS00138
DomainIGc2

CILP CADM4 ROR1 CD3E CADM1 CD276 MYBPC3

3.28e-032351537SM00408
DomainIg_sub2

CILP CADM4 ROR1 CD3E CADM1 CD276 MYBPC3

3.28e-032351537IPR003598
Domain-

TPP2 MBTPS1

3.49e-031115323.40.50.200
DomainDUF1220

NBPF9 NBPF14

3.49e-03111532PF06758
DomainPeptidase_S8/S53_dom

TPP2 MBTPS1

3.49e-03111532IPR000209
DomainNBPF_dom

NBPF9 NBPF14

3.49e-03111532IPR010630
DomainPeptidase_S8

TPP2 MBTPS1

3.49e-03111532PF00082
DomainNBPF

NBPF9 NBPF14

3.49e-03111532PS51316
DomainC8

ZAN SSPOP

4.17e-03121532PF08742
DomainTIL

ZAN SSPOP

4.17e-03121532PF01826
DomainC2-set_2

CADM4 CADM1 CD276

4.57e-03411533PF08205
DomainCD80_C2-set

CADM4 CADM1 CD276

4.57e-03411533IPR013162
DomainUnchr_dom_Cys-rich

ZAN SSPOP

4.90e-03131532IPR014853
DomainC8

ZAN SSPOP

4.90e-03131532SM00832
Domain-

MRC1 MRC2

4.90e-031315322.10.10.10
DomainNHL

TENM4 TENM1

4.90e-03131532PS51125
DomainEGF_CA

BMP1 MEGF8 ADGRE4P C1R

5.47e-03861534PF07645
DomainGelsolin

VILL SEC24B

5.69e-03141532PF00626
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH12

5.69e-03141532IPR024317
DomainFN_type2_col-bd

MRC1 MRC2

5.69e-03141532IPR000562
DomainFN2_2

MRC1 MRC2

5.69e-03141532PS51092
DomainDynein_heavy_dom-2

DNAH3 DNAH12

5.69e-03141532IPR013602
DomainDHC_N2

DNAH3 DNAH12

5.69e-03141532PF08393
DomainGelsolin-like_dom

VILL SEC24B

5.69e-03141532IPR007123
DomainTIL_dom

ZAN SSPOP

5.69e-03141532IPR002919
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH12

5.69e-03141532IPR011704
DomainFN2_1

MRC1 MRC2

5.69e-03141532PS00023
DomainAAA_8

DNAH3 DNAH12

5.69e-03141532PF12780
DomainuDENN

DENND4A DENND4B

5.69e-03141532SM00800
Domainfn2

MRC1 MRC2

5.69e-03141532PF00040
DomainFN2

MRC1 MRC2

5.69e-03141532SM00059
DomainNeurexin-like

CADM4 CADM1

5.69e-03141532IPR003585
Domain4.1m

CADM4 CADM1

5.69e-03141532SM00294
DomainAAA_5

DNAH3 DNAH12

5.69e-03141532PF07728
DomainDHC_fam

DNAH3 DNAH12

6.53e-03151532IPR026983
DomainuDENN

DENND4A DENND4B

6.53e-03151532PF03456
DomainDynein_heavy

DNAH3 DNAH12

6.53e-03151532PF03028
DomainDynein_heavy_dom

DNAH3 DNAH12

6.53e-03151532IPR004273
DomainDENN

DENND4A DENND4B

7.42e-03161532SM00799
DomainVWF_type-D

ZAN SSPOP

7.42e-03161532IPR001846
DomainDENN

DENND4A DENND4B

7.42e-03161532PF02141
DomainVWFD

ZAN SSPOP

7.42e-03161532PS51233
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF8 NBPF20 NBPF19 NBPF9 NBPF10 NBPF14

4.77e-1021162616079250
Pubmed

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.

GNAI1 GNAI3 GNAT1 GNAT2

9.32e-081016248521505
Pubmed

BMP signaling initiates a neural crest differentiation program in embryonic rat CNS stem cells.

GDF6 SMAD1 SMAD5

9.92e-083162315246821
Pubmed

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.

GNAI1 GNAI3 GNAT1 GNAT2

3.14e-071316248208289
Pubmed

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.

GNAI1 GNAI3 GNAT1 GNAT2

3.14e-0713162416892066
Pubmed

Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus.

SMAD1 SMAD3 SMAD5

3.95e-074162319247629
Pubmed

Interaction of TGFβ and BMP signaling pathways during chondrogenesis.

BMP1 SMAD1 SMAD5

3.95e-074162321297990
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MBTPS1 PPM1E FRMPD1 HEATR5A URB2 PHF8 PLEKHH1 TENM4 MEGF8 KLHL13 DENND4B AQR

5.21e-074071621212693553
Pubmed

Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).

GNAI1 GNAI3 GNAT1 GNAT2

5.95e-0715162411118617
Pubmed

The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo.

FBXL5 TFRC SMAD1 SMAD5

7.90e-0716162421907140
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ARHGAP32 GBF1 UBR4 APC2 PAIP1 NBPF20 TULP3 NBPF19 NBPF9 AJUBA NBPF14 SMAD1

9.28e-074301621235044719
Pubmed

The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines.

SMAD1 SMAD3 SMAD5

9.85e-075162315647271
Pubmed

G-protein alpha subunit interaction and guanine nucleotide dissociation inhibitor activity of the dual GoLoco motif protein PCP-2 (Purkinje cell protein-2).

PTPRU GNAI1 GNAI3

9.85e-075162316298104
Pubmed

The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter.

SMAD1 SMAD3 SMAD5

9.85e-075162317251190
Pubmed

Smad1-Smad5 ovarian conditional knockout mice develop a disease profile similar to the juvenile form of human granulosa cell tumors.

SMAD1 SMAD3 SMAD5

9.85e-075162319819941
Pubmed

Brightfield proximity ligation assay reveals both canonical and mixed transforming growth factor-β/bone morphogenetic protein Smad signaling complexes in tissue sections.

SMAD1 SMAD3 SMAD5

9.85e-075162325141865
Pubmed

Mad-related genes in the human.

SMAD1 SMAD3 SMAD5

9.85e-07516238673135
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

NBPF8 UBR4 KLHL11 KLHL13 NBPF9 NBPF10 TNFAIP6 NBPF14

1.44e-06170162823314748
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ARHGAP32 WDR64 UBR4 XPC URB2 NEB WDR19 PLEKHH1 USP6 CADM1 DNAH12 MEGF8 LPO IL17RD

1.94e-066381621431182584
Pubmed

Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity.

SMAD1 SMAD3 SMAD5

1.96e-066162318393632
Pubmed

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes.

SMAD1 SMAD3 SMAD5

1.96e-066162310400677
Pubmed

Requirement of Gαi1/3-Gab1 signaling complex for keratinocyte growth factor-induced PI3K-AKT-mTORC1 activation.

GNAI1 GNAI3 GNAT1

1.96e-066162325078664
Pubmed

Smad7 is required for the development and function of the heart.

SMAD1 SMAD3 SMAD5

1.96e-066162318952608
Pubmed

Immunohistochemical expression of Smads 1-6 in the 15-day gestation mouse embryo: signaling by BMPs and TGF-betas.

SMAD1 SMAD3 SMAD5

1.96e-066162311169847
Pubmed

Dynamic regulation of Smad expression during mesenchyme to epithelium transition in the metanephric kidney.

SMAD1 SMAD3 SMAD5

1.96e-066162311850197
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

ARHGAP32 FAM120B CADM4 CD46 PTPRU TULP3 CADM1 PWP2 DHX34 CD276

1.97e-063071621037499664
Pubmed

Regulation of transforming growth factor-beta and bone morphogenetic protein signalling by transcriptional coactivator GCN5.

SMAD1 SMAD3 SMAD5

3.42e-067162315009097
Pubmed

Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski.

SMAD1 SMAD3 SMAD5

3.42e-067162314699069
Pubmed

Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.

SMAD1 SMAD3 SMAD5

3.42e-067162310376010
Pubmed

Negative regulation of BMP/Smad signaling by Tob in osteoblasts.

SMAD1 SMAD3 SMAD5

3.42e-067162311163184
Pubmed

Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2.

SMAD1 SMAD3 SMAD5

3.42e-067162315150273
Pubmed

Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.

SMAD1 SMAD3 SMAD5

3.42e-067162312370310
Pubmed

The regulation of the complement system: insights from genetically-engineered mice.

CD46 CR1 CR1L

3.42e-067162312914820
Pubmed

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.

SMAD1 SMAD3 SMAD5

3.42e-067162314580334
Pubmed

Pkd1 is required for male reproductive tract development.

SMAD1 SMAD3 SMAD5

3.42e-067162323933588
Pubmed

Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.

GNAI1 GNAI3 GNAT1 GNAT2

4.48e-062416242902634
Pubmed

A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension.

SMAD1 SMAD3 SMAD5

5.46e-068162319211612
Pubmed

Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells.

SMAD1 SMAD3 SMAD5

5.46e-068162310647776
Pubmed

Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin.

SMAD1 SMAD3 SMAD5

5.46e-068162312714599
Pubmed

Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter.

SMAD1 SMAD3 SMAD5

5.46e-068162310531362
Pubmed

Computational modelling of Smad-mediated negative feedback and crosstalk in the TGF-β superfamily network.

SMAD1 SMAD3 SMAD5

5.46e-068162323804438
Pubmed

Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.

CD46 CR1 CR1L

5.46e-068162314670299
Pubmed

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

SMAD1 SMAD3 SMAD5

5.46e-068162311278251
Pubmed

TGF-beta signaling by Smad proteins.

SMAD1 SMAD3 SMAD5

5.46e-068162310708949
Pubmed

GATA4 is essential for bone mineralization via ERα and TGFβ/BMP pathways.

SMAD1 SMAD3 SMAD5

8.16e-069162324932701
Pubmed

Holding their own: the noncanonical roles of Smad proteins.

SMAD1 SMAD3 SMAD5

8.16e-069162319018011
Pubmed

TGF-beta signal transduction.

SMAD1 SMAD3 SMAD5

8.16e-06916239759503
Pubmed

Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming.

SMAD1 SMAD3 SMAD5

8.16e-069162330134160
Pubmed

Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations.

SMAD1 SMAD3 SMAD5

8.16e-069162324816837
Pubmed

Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability.

BMP1 SMAD1 SMAD5

8.16e-069162316087734
Pubmed

Dullard/Ctdnep1 regulates endochondral ossification via suppression of TGF-β signaling.

SMAD1 SMAD3 SMAD5

8.16e-069162325155999
Pubmed

The Smad pathway.

SMAD1 SMAD3 SMAD5

8.16e-069162310708948
Pubmed

G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.

GNAI1 GNAI3 GNAT1 GNAT2

8.51e-062816248858601
Pubmed

TGF-β signaling inhibits canonical BMP signaling pathway during palate development.

SMAD1 SMAD3 SMAD5

1.16e-0510162329247325
Pubmed

Spatio-temporal distribution of Smads and role of Smads/TGF-β/BMP-4 in the regulation of mouse bladder organogenesis.

SMAD1 SMAD3 SMAD5

1.16e-0510162323620745
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF8 NBPF9 NBPF14

1.16e-0510162322973535
Pubmed

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).

SMAD1 SMAD3 SMAD5

1.16e-0510162315221015
Pubmed

Protein Arginine Methyltransferase PRMT1 Is Essential for Palatogenesis.

SMAD1 SMAD3 SMAD5

1.16e-0510162329986157
Pubmed

Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice.

SMAD1 SMAD3 SMAD5

1.16e-0510162312543979
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

HYAL4 PLXNA3 ARHGAP32 NBEAL1 CR1 CR1L PDLIM5 TENM1 GNAI3 IL17RD DHX34 PRDM14

1.18e-055521621210737800
Pubmed

Mechanical feedback defines organizing centers to drive digit emergence.

SMAD1 SMAD3 SMAD5

1.59e-0511162335413235
Pubmed

Cardiac disease and arrhythmogenesis: Mechanistic insights from mouse models.

PPP1R13L CACNA1G MYBPC3

1.59e-0511162327766308
Pubmed

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.

SMAD1 SMAD3 SMAD5

1.59e-0511162327741240
Pubmed

Downregulation of bone morphogenetic protein receptor axis during HIV-1 and cocaine-mediated pulmonary smooth muscle hyperplasia: implications for HIV-related pulmonary arterial hypertension.

SMAD1 SMAD3 SMAD5

1.59e-0511162324008158
Pubmed

BMPR-II is dispensable for formation of the limb skeleton.

SMAD1 SMAD3 SMAD5

2.12e-0512162321538804
Pubmed

Smad expression during kidney development.

SMAD1 SMAD3 SMAD5

2.12e-0512162314656760
Pubmed

Crim1KST264/KST264 mice implicate Crim1 in the regulation of vascular endothelial growth factor-A activity during glomerular vascular development.

SMAD1 SMAD3 SMAD5

2.12e-0512162317460146
Pubmed

Functional identification of transcription control sequences of the mouse Crry gene.

CR1 CR1L

2.16e-05216228335915
Pubmed

The Biology of Cell-free DNA Fragmentation and the Roles of DNASE1, DNASE1L3, and DFFB.

DFFB DNASE1

2.16e-052162232004449
Pubmed

Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1.

MRC1 MRC2

2.16e-052162219224860
Pubmed

Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina.

GNAT1 GNAT2

2.16e-05216222534964
Pubmed

Crry/p65, a membrane complement regulatory protein, has costimulatory properties on mouse T cells.

CR1 CR1L

2.16e-052162210779754
Pubmed

Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion.

CR1 CR1L

2.16e-052162216444293
Pubmed

Mannose receptor regulation of macrophage cell migration.

MRC1 MRC2

2.16e-052162217596337
Pubmed

Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Crry, the two genetic homologues of human CR1.

CR1 CR1L

2.16e-05216221730912
Pubmed

TRPV4 heats up ANO1-dependent exocrine gland fluid secretion.

ANO1 TRPV4

2.16e-052162229187363
Pubmed

BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells.

SMAD1 SMAD5

2.16e-052162226711875
Pubmed

The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signalling.

SMAD1 SMAD5

2.16e-052162211451566
Pubmed

Association of human mannose receptor in sexual transmission of human immunodeficiency virus in serodiscordant couples.

MRC1 MRC2

2.16e-052162223148569
Pubmed

Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.

CR1 CR1L

2.16e-052162219740350
Pubmed

Modulation of water efflux through functional interaction between TRPV4 and TMEM16A/anoctamin 1.

ANO1 TRPV4

2.16e-052162224509911
Pubmed

Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium.

TRPV4 CACNA1G

2.16e-052162219617313
Pubmed

Coding sequence, exon-intron structure and chromosomal localization of murine TNF-stimulated gene 6 that is specifically expressed by expanding cumulus cell-oocyte complexes.

NEB TNFAIP6

2.16e-05216229427551
Pubmed

CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor.

MRC1 MRC2

2.16e-052162215047828
Pubmed

Modulation of D-serine levels in brains of mice lacking PICK1.

SRR PICK1

2.16e-052162218191108
Pubmed

Functional interchangeability of rod and cone transducin alpha-subunits.

GNAT1 GNAT2

2.16e-052162219815523
Pubmed

Elevated PICK1 mRNA in schizophrenia increased SRR mRNA in suicide.

SRR PICK1

2.16e-052162220385472
Pubmed

Expansion of the complement receptor gene family. Identification in the mouse of two new genes related to the CR1 and CR2 gene family.

CR1 CR1L

2.16e-05216222952719
Pubmed

BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development.

SMAD1 SMAD5

2.16e-052162232210087
Pubmed

Scotopic and photopic visual thresholds and spatial and temporal discrimination evaluated by behavior of mice in a water maze.

GNAT1 GNAT2

2.16e-052162216683905
Pubmed

Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor.

MRC1 MRC2

2.16e-052162217360361
Pubmed

Requirement of Gαi1 and Gαi3 in interleukin-4-induced signaling, macrophage M2 polarization and allergic asthma response.

GNAI1 GNAI3

2.16e-052162233754034
Pubmed

BMP receptor-integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow.

SMAD1 SMAD5

2.16e-052162223387849
Pubmed

The extended multidomain solution structures of the complement protein Crry and its chimeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy.

CR1 CR1L

2.16e-052162212767833
Pubmed

Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.

SMAD1 SMAD5

2.16e-05216228799132
Pubmed

Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium.

CADM4 CADM1

2.16e-052162235213073
Pubmed

Regulation of complement activity via the alternative pathway in placentas of mouse spontaneous abortions.

CR1 CR1L

2.16e-052162220484840
Pubmed

Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.

SMAD1 SMAD3

2.16e-052162220147459
Pubmed

Adaptation to background light enables contrast coding at rod bipolar cell synapses.

GNAT1 GNAT2

2.16e-052162224373883
Pubmed

Diminished Cone Sensitivity in cpfl3 Mice Is Caused by Defective Transducin Signaling.

GNAT1 GNAT2

2.16e-052162232315379
Cytoband1q21.1

NBPF8 NBPF9 NBPF10 NBPF14

7.11e-056216241q21.1
Cytoband19q13.32

FKRP HIF3A PPP1R13L KPTN

1.42e-0474162419q13.32
Cytoband4q22

GRID2 PDLIM5

4.38e-04916224q22
GeneFamilyNeuroblastoma breakpoint family

NBPF8 NBPF26 NBPF20 NBPF19 NBPF9 NBPF10 NBPF14

4.73e-11231077662
GeneFamilySMAD family

SMAD1 SMAD3 SMAD5

1.10e-0581073750
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CD46 CR1 CR1L C1R SEZ6

2.17e-055710751179
GeneFamilyComplement system|Sushi domain containing

CD46 CR1 CR1L C1R

5.90e-05361074492
GeneFamilyADAM metallopeptidase domain containing|CD molecules

MRC1 CD46 CR1 TFRC TLR10 CD3E MRC2 TNFRSF8 CCR3 CD276

1.16e-0439410710471
GeneFamilyBone morphogenetic proteins|Astacins

MEP1A BMP1

5.12e-0461072894
GeneFamilyCD molecules|Toll like receptors

TLR10 TLR5

1.51e-03101072948
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

CADM4 CADM1 CD276

1.70e-03401073592
GeneFamilyDyneins, axonemal

DNAH3 DNAH12

4.45e-03171072536
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_200

CADM1 EFNA5 TENM4 CACNA1G TNFAIP6 IL17RD

8.25e-06651566gudmap_kidney_P3_CapMes_Crym_k4_200
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1E PLPPR1 CADM1 EFNA5 TENM4 KLHL13 PCCA DNASE1

5.15e-071911628963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

RASA3 BMP1 ELFN1 MRC2 C1R TRPV4 AJUBA SMAD3

6.02e-0719516285562665dd3beb70e2358aa32611a337bef5731c1
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 LMLN CFAP74

2.91e-061691627fba841664939c771881ba97f14ef1df6635c04ff
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

PPM1E BMP1 CADM1 MRC2 TRPV4 GNAI1 CD276

3.40e-061731627c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROR1 ADAMTS13 CR1L BMP1 TENM1 C1R TRPV4

3.95e-061771627ac90e4ce5be304a5a7473736397327010f2d1999
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF26 OTOP3 PLPPR1 NBPF19 CCNYL1 NBPF10 MSLN

4.41e-0618016277c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF26 OTOP3 NBPF19 CCNYL1 NBPF9 NBPF10 MSLN

4.41e-061801627b234668bf181522807470e396792e1b54890b719
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CILP GRID2 KCND3 MRC2 TENM1 C1R AJUBA

5.28e-0618516279faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLPPR1 CADM1 EFNA5 TENM4 KLHL13 GNAI1 DNASE1

5.47e-0618616271850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLPPR1 CADM1 EFNA5 TENM4 KLHL13 GNAI1 DNASE1

5.47e-0618616274dafc215c42e7949f932a3627359c107943b5d6b
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

PPM1E CADM1 EFNA5 TENM4 KLHL13 TLR5 GNAI1

5.67e-0618716272ce8038d9d1302e850c1bb536e755598f77ba4b9
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ROR1 PPM1E NEB PDLIM5 KCND3 FGF12 MYBPC3

5.87e-0618816276d249fe92d51a19da19ec14bb2262d394255d577
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

ROR1 PPP1R13L CADM1 EFNA5 KCND3 FGF12 MYBPC3

5.87e-0618816270758b474457efa36488e0195f7357100f4b6a090
ToppCellCOPD-Myeloid-cMonocyte|COPD / Disease state, Lineage and Cell class

NBPF26 NBPF19 ACSL3 NBPF10 TNFAIP6 NBPF14 DHX34

6.08e-061891627d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR1 ANO1 GRID2 EFNA5 TENM4 KLHL13 SMAD3

6.08e-06189162745e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR1 ANO1 GRID2 EFNA5 TENM4 KLHL13 SMAD3

6.51e-061911627b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GDF6 PTPRU PLPPR1 CHRNA2 DACT1 ELFN1

6.54e-061251626d05556ea185c15815a4f8643f1c01185badbeece
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 ANO1 PLPPR1 CHRNA2 ELFN1 TOX3 TENM1

6.74e-061921627bf1943715085c4124b1675888b0615c9500ec888
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 ANO1 PLPPR1 CHRNA2 ELFN1 TOX3 TENM1

7.21e-06194162702a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

ROR1 PDLIM5 CADM1 EFNA5 KCND3 FGF12 MYBPC3

7.46e-061951627f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF26 CD46 MEP1A NBPF19 CCNYL1 NBPF10 MSLN

7.46e-061951627e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCell15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

ROR1 GDF6 BMP1 DACT1 MRC2 C1R TNFAIP6

7.71e-06196162754aefcebf13704f51de84379e2e22ec0734b9461
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GDF6 PTPRU PLPPR1 CHRNA2 DACT1 ELFN1

7.84e-061291626f83187c0bb06528127b8d2d56674ab1946846951
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF26 OTOP3 MEP1A NBPF19 CCNYL1 VILL MSLN

8.51e-06199162701d101b0fd5326947a9e5dddae6c2f93ab6e0a4d
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF26 OTOP3 MEP1A NBPF19 CCNYL1 VILL MSLN

8.51e-0619916276d439c0c5e6b72fcb8d4dc72e7445eb6a01fe095
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA3 CADM4 GRM3 PLEKHH1 GNAI1 NIPA1 TNFAIP6

8.79e-06200162756f1f007ba8c9188a4b10e52744f1e50dc0f155a
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ROR1 SLC6A19 GRID2 EFNA5 CACNA1G CD276

1.30e-0514116267ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRU PLPPR1 CHRNA2 DACT1 ELFN1 TOX3

1.47e-05144162671107275767a0728541a3695715c44874b3e5efc
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

PPM1E BMP1 CADM1 MRC2 TRPV4 CD276

1.65e-05147162687c24843cb0e87ad42e725d08423131a5d2d25a3
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A GPR65 NEB MRC2 TNFAIP6 MYBPC3

2.00e-05152162618194f757d319958f26e5a91f56d89f25711236f
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

BMP1 CADM1 MRC2 TRPV4 PLP2 CD276

2.66e-051601626ab769516f9f7798d1390ef215caf22a2d3d53e63
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRU PLPPR1 CHRNA2 DACT1 ELFN1 TOX3

2.76e-051611626dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

TTC21A PPM1E ADAMTS13 CFAP43 DNAH12 CFAP74

2.96e-05163162643194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellfacs-Kidney-nan-3m-Lymphocytic|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 DENND4A DFFB CD3E PPP3CC GNAT2

3.17e-051651626ba041deb0d9c187f251493ccd4794b5f09abd5aa
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA3 IL12RB2 ZAN PPM1E TULP3 GCLC

3.17e-0516516260edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA3 IL12RB2 ZAN PPM1E TULP3 GCLC

3.17e-051651626fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 IDUA CADM1 ADGRE4P TRPV4 CD276

3.28e-05166162691eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

CILP BMP1 DACT1 MRC2 C1R TNFAIP6

3.50e-051681626aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL12RB2 WDR64 CD3E CADM1 TNFRSF8 WSCD2

3.74e-051701626aeac9de12efc727313946a77823aba8ab7cdfbfb
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL12RB2 WDR64 CD3E CADM1 TNFRSF8 WSCD2

3.74e-0517016269a21048b0248a0cae00ec2d71d5056a678495385
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

ZAN ANO1 TLR10 CADM1 KCND3 KLHL13

4.00e-0517216261215f61f115b042f84721b64c2ed1f48081535f1
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 ADAT3 GPR65 PPP1R13L TLR5 TRPV4

4.13e-05173162612c6875f881cb0fbff09d753b53c1cce7a95527f
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP CD46 KLHL11 KCND3 CACNA1G MSLN

4.40e-05175162659249c9e83952d7277010e7be3c779e26399eb5d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP CD46 KLHL11 KCND3 CACNA1G MSLN

4.40e-051751626b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DENND4A PPM1E MCMDC2 PLBD2 VILL

4.69e-051771626384f841aa7b2d05815af7885e481f5affc55d897
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DENND4A PPM1E MCMDC2 PLBD2 VILL

4.69e-0517716260e9e44119653abfd270e602e5e477a15e774638f
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 APC2 SSPOP DACT1 GNAI1 AJUBA

4.69e-0517716268684d47a547e2a06496f15e8da0200ecddc431e0
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 APC2 SSPOP DACT1 GNAI1 AJUBA

4.69e-05177162665709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DENND4A PPM1E MCMDC2 PLBD2 VILL

4.69e-051771626c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

PLK2 ROR1 TLR10 CADM1 KCND3 MRC2

4.69e-05177162633cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAH3 PPM1E TMEM212 CFAP43 DNAH12 CFAP74

4.84e-051781626de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CADM4 ANO1 DDC MICU1 CADM1 NIPA1

4.84e-051781626a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CADM4 ANO1 DDC MICU1 CADM1 NIPA1

4.84e-051781626b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

4.99e-0517916265e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1E PLPPR1 CADM1 EFNA5 GNAI1 DNASE1

5.15e-051801626a17dbe03597b81e7a1fe2bf2d23e59e55c615a2a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DNAH3 PLPPR1 ELFN1 KLHL13 TOX3 TENM1

5.15e-051801626b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1E PLPPR1 CADM1 EFNA5 GNAI1 DNASE1

5.15e-051801626eee71184ebed2694d3e60f579a44b3cf7dd2cd35
ToppCellCOVID-19_Convalescent|World / Disease condition and Cell class

NBPF26 NBPF20 NBPF19 HAUS4 NBPF14 TRAV14DV4

5.31e-051811626a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD1 DACT1 CADM1 TENM4 GNAI1 AJUBA

5.47e-051821626aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD1 DACT1 CADM1 TENM4 GNAI1 AJUBA

5.47e-0518216269edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH3 TMEM212 CFAP43 DNAH12 CFAP74 TRPV4

5.47e-0518216267ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 GRID2 NBPF19 NBPF10 TENM1 NBPF14

5.81e-051841626658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 PPM1E TMEM212 CFAP43 DNAH12 CFAP74

5.81e-0518416265daff849625f2f41d56615569c0ed59cd733b34c
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF26 OTOP3 NBPF19 CCNYL1 NBPF10 MSLN

5.99e-051851626c3d1a312569f3d619f7295812741cbf068ec6c1f
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

ROR1 PDLIM5 CADM1 EFNA5 FGF12 MYBPC3

5.99e-0518516266baccb26f999145e51b91d94315bf8d4655bef31
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PLPPR1 CADM1 EFNA5 TENM4 GNAI1 DNASE1

5.99e-05185162603f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

5.99e-0518516265e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRID2 ADAMTS13 EFNA5 TENM4 KLHL13 SMAD3

5.99e-0518516263b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1E PLPPR1 CADM1 EFNA5 KLHL13 DNASE1

6.36e-051871626b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

MRC1 NEB CADM1 BRCA2 OSBPL1A TRPV4

6.36e-05187162659e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GDF6 PPM1E CADM1 EFNA5 KLHL13 GNAI1

6.55e-0518816262ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DNAH3 PPM1E TMEM212 CFAP43 DNAH12 CFAP74

6.55e-0518816262b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

6.74e-051891626a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

ROR1 PDLIM5 EFNA5 KCND3 FGF12 MYBPC3

6.74e-0518916265e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1E PLPPR1 CADM1 EFNA5 TENM4 KLHL13

6.94e-051901626cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

ROR1 PDLIM5 EFNA5 KCND3 FGF12 MYBPC3

6.94e-051901626de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1E CADM1 EFNA5 TENM4 KLHL13 DNASE1

6.94e-0519016263dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

ROR1 PDLIM5 EFNA5 KCND3 FGF12 MYBPC3

6.94e-051901626fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

7.15e-0519116261e21de183a9c09cfb6aad3f9b948087fb6bad061
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

ROR1 PDLIM5 EFNA5 KCND3 FGF12 MYBPC3

7.15e-05191162625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellE16.5-Epithelial-Epithelial_Airway|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

7.35e-051921626bb7eb51bc079acacde42d8e55ba06d03eba2ea28
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 FRMPD1 ANO1 KLHL13 TOX3 TENM1

7.35e-0519216260003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

ROR1 PDLIM5 EFNA5 KCND3 FGF12 MYBPC3

7.35e-051921626ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ROR1 ANO1 DACT1 EFNA5 TOX3 SMAD3

7.57e-051931626e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ROR1 PDLIM5 CADM1 EFNA5 FGF12 MYBPC3

7.57e-051931626dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBF1 UBR4 DPP3 NEB DDC BMP1

7.57e-051931626471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBF1 UBR4 DPP3 NEB DDC BMP1

7.57e-051931626fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 GRID2 PTPRU ELFN1 TOX3 TENM1

7.57e-051931626658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 GRID2 PTPRU ELFN1 TOX3 TENM1

7.79e-05194162683863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellRA-03._Atrial_Cardiomyocyte|RA / Chamber and Cluster_Paper

ROR1 PDLIM5 EFNA5 KCND3 FGF12 MYBPC3

7.79e-051941626c3535f7cc0076653c72db582047cff053c322397
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

8.01e-0519516263486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

GRM3 CADM1 EFNA5 KLHL13 GNAI1 SEZ6

8.01e-051951626574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

8.01e-051951626e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

PPM1E CADM1 EFNA5 TENM4 KLHL13 GNAI1

8.24e-05196162604f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell15-Trachea-Mesenchymal|Trachea / Age, Tissue, Lineage and Cell class

ROR1 BMP1 DACT1 MRC2 C1R TNFAIP6

8.24e-0519616267e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCellfacs-Brain_Non-Myeloid-Cortex|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP32 CADM4 GRM3 PLEKHH1 ACSL3 NIPA1

8.24e-051961626256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANO1 PLPPR1 CHRNA2 ELFN1 TOX3 TENM1

8.24e-0519616267af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAH3 TTC21A TMEM212 CFAP43 DNAH12 CFAP74

8.24e-051961626d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 TTC21A CFAP43 DNAH12 LMLN CFAP74

8.47e-05197162674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF26 OTOP3 NBPF19 CCNYL1 NBPF10 MSLN

8.71e-051981626efdbac7a3a02bff4ca48841772e0c136556c2b9b
DrugSulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A

APC2 ADAMTS13 PHF8 KLHL11 BMP1 MEGF8 VILL KCND3 TRPV4 CACNA1G

1.22e-06198157105257_UP
Drugaspirin, USP; Down 200; 100uM; HL60; HT_HG-U133A

GPR65 MCPH1 RASA3 FRMPD1 TMEM212 BMP1 MEGF8 KCND3 TNFRSF8 CACNA1G

1.33e-06200157102664_DN
DrugOxyphenbutazone [129-20-4]; Down 200; 12.4uM; HL60; HT_HG-U133A

TMEM212 URB2 NEB CR1 BMP1 CADM1 MRC2 TNFRSF8 SMAD5

8.40e-0619415796160_DN
DrugPesticides

NBPF8 NBPF20 NBPF9 MTNR1B NBPF10 GNAI3 NBPF14 SMAD5

9.82e-061501578ctd:D010575
DrugOxytetracycline dihydrate [6153-64-6]; Up 200; 8uM; PC3; HT_HG-U133A

RASA3 FKRP APC2 PPM1E FRMPD1 KCND3 TNFRSF8 FGF12 DHX34

1.03e-0519915795772_UP
DiseaseMcCune Albright syndrome (implicated_via_orthology)

GNAI1 GNAI3 GNAT1 GNAT2

4.91e-0881544DOID:1858 (implicated_via_orthology)
Diseaseatypical hemolytic-uremic syndrome (is_marker_for)

CD46 ADAMTS13

8.09e-0531542DOID:0080301 (is_marker_for)
Diseasemuscle measurement

PLK2 NEB

1.61e-0441542EFO_0004515
DiseaseColorectal Carcinoma

DNAH3 APC2 PPM1E PHETA1 GRID2 CD46 PTPRU TFRC DACT1 KCND3 TENM1 SMAD3

3.32e-0470215412C0009402
DiseaseBare Lymphocyte Syndrome

TFRC CD3E

4.00e-0461542C0242583
Diseaseblood sedimentation

CR1 CR1L

5.59e-0471542EFO_0004304
Diseasesyndromic X-linked intellectual disability (implicated_via_orthology)

PHF8 PHF2

7.42e-0481542DOID:0060309 (implicated_via_orthology)
DiseaseSudden Cardiac Arrest

KCND3 MYBPC3

7.42e-0481542C1720824
DiseaseSudden Cardiac Death

PPP1R13L MYBPC3

7.42e-0481542C0085298
Diseasebody shape measurement

FGF12 DNASE1

7.42e-0481542EFO_0801227
DiseaseBipolar Disorder

ROR1 PHETA1 GRM3 DDC CHRNA2 PDLIM5 TENM4 PPP3CC BRCA2

9.39e-044771549C0005586
Diseaseasparaginase-induced acute pancreatitis

NEB PDLIM5

9.51e-0491542EFO_1001507
Diseasediabetes mellitus biomarker

GRID2 CCR3

1.18e-03101542EFO_0006842
DiseaseAlzheimer disease, gastroesophageal reflux disease

PTPRU PPP1R13L GRM3 CR1L CHRNA2 DNAH12

1.29e-032281546EFO_0003948, MONDO_0004975
DiseaseSystemic lupus erythematosus

TLR5 DNASE1

1.44e-03111542cv:C0024141
Diseasebeta wave measurement

KCND3 OSBPL1A

1.73e-03121542EFO_0006871
Diseasesystemic lupus erythematosus (is_marker_for)

CD46 ADAMTS13 CCR3

1.91e-03471543DOID:9074 (is_marker_for)
DiseaseAmino Acid Metabolism, Inherited Disorders

XPC GCLC

2.03e-03131542C0750905
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

SMAD1 SMAD5

2.03e-03131542DOID:0050787 (implicated_via_orthology)
DiseaseAmino Acid Metabolism, Inborn Errors

XPC GCLC

2.03e-03131542C0002514
DiseaseTourette syndrome

PTPRU TENM4 CD276

2.28e-03501543EFO_0004895
Diseasepulse pressure measurement

NBEAL1 ANO1 HEATR5A CD46 CR1L SSPOP PDLIM5 CD3E TENM4 MEGF8 GCAT MRC2 MTNR1B DHX34 SMAD3 MYBPC3

2.59e-03139215416EFO_0005763
Diseasepancreatic cancer (is_implicated_in)

XPC BRCA2 MSLN SMAD3

2.86e-031121544DOID:1793 (is_implicated_in)
Diseaseidiopathic scoliosis (implicated_via_orthology)

MBTPS1 SSPOP

3.10e-03161542DOID:0060250 (implicated_via_orthology)
Diseaseovarian cancer (is_implicated_in)

TFRC BRCA2 MSLN

3.16e-03561543DOID:2394 (is_implicated_in)
DiseaseColorectal Neoplasms

APC2 PPM1E PHETA1 TFRC DACT1 SMAD3

3.42e-032771546C0009404
DiseaseWithdrawal Symptoms

GNAI1 SMAD1 SMAD5

3.49e-03581543C0087169
DiseaseDrug Withdrawal Symptoms

GNAI1 SMAD1 SMAD5

3.49e-03581543C0086189
DiseaseSubstance Withdrawal Syndrome

GNAI1 SMAD1 SMAD5

3.49e-03581543C0038587
DiseaseMAJOR AFFECTIVE DISORDER 2

PHETA1 DDC

3.50e-03171542C1839839
DiseaseTactile Amnesia

GNAI1 GNAI3

3.50e-03171542C0750906
DiseaseAmnestic State

GNAI1 GNAI3

3.50e-03171542C0750907
DiseaseDissociative Amnesia

GNAI1 GNAI3

3.50e-03171542C0236795
DiseaseHysterical amnesia

GNAI1 GNAI3

3.50e-03171542C0233750
DiseaseTemporary Amnesia

GNAI1 GNAI3

3.50e-03171542C0233796
DiseaseAmnesia

GNAI1 GNAI3

3.50e-03171542C0002622
DiseaseGlobal Amnesia

GNAI1 GNAI3

3.50e-03171542C0262497
DiseaseMHPG measurement, 5-HIAA measurement

CADM1 KLHL13

3.50e-03171542EFO_0005132, EFO_0005133
DiseaseAlzheimer disease, family history of Alzheimer’s disease

CR1 CR1L CHRNA2 IL17RD

3.56e-031191544EFO_0009268, MONDO_0004975
DiseaseOmenn Syndrome

TFRC CD3E

4.37e-03191542C2700553
Diseasecortical surface area measurement

ZAN MCPH1 NBEAL1 ROR1 IDUA MPRIP DACT1 HAUS4 EFNA5 TOX3 WSCD2 AJUBA IL17RD PCCA SMAD5

4.64e-03134515415EFO_0010736
Diseasedaytime rest measurement

FAM120B EFNA5 GCLC MTNR1B WSCD2 CCR3

4.64e-032951546EFO_0007828
DiseaseSevere Combined Immunodeficiency

TFRC CD3E

4.83e-03201542C0085110

Protein segments in the cluster

PeptideGeneStartEntry
ISYLCPDDVGYLASV

URB2

751

Q14146
DEDGLPYLCTGYDLY

ADAT3

271

Q96EY9
CGTYLASYSSLPEFE

CFAP43

121

Q8NDM7
ELYSNPFYCSCELLG

ELFN1

186

P0C7U0
VNGSVYCEEDYLFSG

AJUBA

381

Q96IF1
TYEALCDYNGFPFRE

CARMIL2

161

Q6F5E8
TADLTGCYDLPEDYI

GRM3

556

Q14832
FYEVGCVSTPLEAGY

ABHD16A

291

O95870
FLAGIIDYDHPDCYE

ADGRE4P

91

Q86SQ3
DCCAEIYPDVTYAFV

CHRNA2

246

Q15822
VPGDASYTCETAGYF

AQR

921

O60306
ITCSSYRGYPEAEVF

CD276

381

Q5ZPR3
LCLYEDGTELTEDYF

DFFB

46

O76075
DAAYAGSAFICPEFR

DDC

271

P20711
DEDSYIVFTYRPCGC

BMP1

171

P13497
EPSEGCFYDYVKISA

C1R

66

P00736
AGSAELYCASDIYEA

CCNYL1

21

Q8N7R7
LYCASDIYEAVSGDA

CCNYL1

26

Q8N7R7
YGSQLAPETFYRECD

ADAMTS13

1286

Q76LX8
GLICRYPQEDYESFS

DENND4A

211

Q7Z401
YCSYEGAVDLDALTD

NBEAL1

2241

Q6ZS30
SLCPFYGEDFYCEIP

RASA3

56

Q14644
CYPEYAGSNTYEEAA

GNAI1

286

P63096
DDYINASCVEGLSPY

PTPN23

1241

Q9H3S7
EASGPAIACQYFTLY

OTOP3

361

Q7RTS5
ISAYDDELAFYGILP

KCND3

111

Q9UK17
GEIDLSACYDVTEYP

MPRIP

431

Q6WCQ1
IAVYFDYSCEGDVPG

IL17RD

476

Q8NFM7
YGLDLCEFPLDYTSQ

MCMDC2

111

Q4G0Z9
ALEALSCGESSYDDY

MCPH1

401

Q8NEM0
FEYLDAVTYSCDPAP

CD46

181

P15529
YYASGCSIAKFPEDG

MBTPS1

786

Q14703
CYPEYTGSNTYEEAA

GNAI3

286

P08754
ICFPDYDGPNTYEDA

GNAT1

281

P11488
YGGSVEIADYCPFSQ

LMLN

471

Q96KR4
IYCDYLDFGINLTPE

IL12RB2

176

Q99665
FFVGSLEYDPRIYSC

MTNR1B

176

P49286
YTLGECGLISFSDYI

MICU1

196

Q9BPX6
LEYVAINDPDCSFYT

GRID2

746

O43424
CAGDSEFYSYVEFPI

PLXNA3

266

P51805
YCDYEPGSEYNLDSI

KPTN

116

Q9Y664
ANSYPYDFVDCSAID

LPO

686

P22079
AASPFYRGYVSDIDC

GCLC

281

P48506
PFEAISYLTGECNYG

DNAH12

2696

Q6ZR08
DEDSETYFYPCPCGD

DPH3

16

Q96FX2
CTYDYLFVYDGDSPR

MEGF8

81

Q7Z7M0
YGSEEDLCALPYHEV

MRC2

161

Q9UBG0
YEGYATVTDAPPECF

DPP3

641

Q9NY33
DTLDTLTAFYPGYLC

MSLN

436

Q13421
LSVDPDAECKYGLYF

ANO1

41

Q5XXA6
EDAILYPSCYDANAG

GCAT

126

O75600
YPSCYDANAGLFEAL

GCAT

131

O75600
VFHLEDGEPYCETDY

PDLIM5

516

Q96HC4
DGEPYCETDYYALFG

PDLIM5

521

Q96HC4
VVEYCEPCGFEATYL

MIEN1

26

Q9BRT3
VECRVYAEDPYKSFG

PCCA

396

P05165
ETCPGLFLYTKVEDY

PRSS54

246

Q6PEW0
TECLYSVDPATFDAY

OSBPL1A

776

Q9BXW6
YCDYGPLVELACSDT

OR6C4

176

Q8NGE1
YSPDGALCDVDAYGT

ARHGAP32

1661

A7KAX9
GCEDYPTLSEYVQDF

PAIP1

151

Q9H074
ATCLFGYDAYVTFPV

PLP2

121

Q04941
FGIRPDDYLYSLCSE

PIPSL

101

A2A3N6
FCYDVALEYLEGLES

PTPRU

1431

Q92729
TEDYLILACDGFYDT

PPM1E

426

Q8WY54
GSPLFGCLYEANDYE

NEU2

346

Q9Y3R4
LYEYKVFGVLEDCSP

PCTP

51

Q9UKL6
ISDEGRYFCQLYTDP

CADM1

116

Q9BY67
PTEEAVYCFYGNDSD

APC2

1501

O95996
VACGSLEYDPYSIYE

HEATR5A

746

Q86XA9
GDYLSECVGYFVDED

KLHL11

371

Q9NVR0
YDDVLSCEYYSPILD

KLHL13

551

Q9P2N7
DYILFDCPGQIELYT

GPN3

101

Q9UHW5
PYAYVASDSEYSAEC

DACT1

716

Q9NYF0
GLAPFVYLSDECYNL

BRCA2

3086

P51587
FSEPGSCYEELLKYL

CACNA1G

426

O43497
FGTTSYYDDVGLLCE

CCR3

11

P51677
FYSCEPSYDLRGAAS

CR1

1676

P17927
PFDALTYLTGECNYG

DNAH3

3721

Q8TD57
EYFYPSTDCVDFAPS

COLCA2

121

A8K830
VSAVDSYYYDDGCEP

DNASE1

111

P24855
DPVAFEYLYLQSCSD

FRMPD1

276

Q5SYB0
DDFEFPIGTYLNYEC

CR1L

51

Q2VPA4
YYIPAEDFSGLAVID

HYAL4

131

Q2M3T9
LEDEGGYFCQLYTED

CADM4

96

Q8NFZ8
EFSELEQSGYYVCYP

CD3E

86

P07766
YYDACSEGLRAASPA

IDUA

201

P35475
YCYDGFPELRAELFE

DENND4B

701

O75064
DYLDVFCPHYEDSVP

EFNA5

56

P52803
IPSFVTELYINYDCD

GBF1

531

Q92538
DLVSACPSLNDEYFY

FBXL5

646

Q9UKA1
CFGTVVGDTPAYLYE

FKRP

296

Q9H9S5
CFTLLCYYDPNSDAD

HAUS4

176

Q9H6D7
GPGVCFRLYAESDYD

DHX34

496

Q14147
LPLDTQCGDYYSALY

SEC24B

81

O95487
PYREGYADCATYLAD

PPP1R13L

736

Q8WUF5
ALECFDSSVFGAIYY

NIPA1

251

Q7RTP0
SPSEVDFGYCTIYEA

CFAP74

921

Q9C0B2
PEDEAEYYCLLSYSG

IGLV7-46

101

A0A075B6I9
LGEDTDYLIYDTCPY

FAM120B

176

Q96EK7
PNLYYGELCEEVVSS

MUC17

4161

Q685J3
TTTDYDTDKLFGYCP

MRC1

196

P22897
GEGYLYSSDVFTPEC

FGF12

131

P61328
LEYEAYHCEGVCDFP

GDF6

376

Q6KF10
GYVDECARSSPVDYF

SLC6A19

161

Q695T7
YATCDAPVDNAGFLY

PHETA1

11

Q8N4B1
LDACFKDSDYVYPSL

PHF2

866

O75151
FDGLAFTYPGACEYL

SSPOP

1026

A2VEC9
YGDCYEKFLDIPVSL

PRDM14

366

Q9GZV8
CLYESYFDPGKSISE

TLR10

666

Q9BXR5
FLSLCYEYLGGESSI

TMEM184B

126

Q9Y519
DSCQPYGSSFYALEE

NBPF8

766

Q3BBV2
DSCQPYGSSFYALEE

NBPF9

801

P0DPF3
DSCQPYGSSFYALEE

NBPF10

801

Q6P3W6
DSCQPYGSSFYALEE

NBPF10

2021

Q6P3W6
DSCQPYGSSFYALEE

NBPF10

3241

Q6P3W6
DSCQPYGSSFYALEE

NBPF14

461

Q5TI25
DSCQPYGSSFYALEE

NBPF19

1506

A0A087WUL8
DSCQPYGSSFYALEE

NBPF19

2726

A0A087WUL8
DSCQPYGSSFYALEE

NBPF20

186

P0DPF2
DSCQPYGSSFYALEE

NBPF20

1406

P0DPF2
DSCQPYGSSFYALEE

NBPF20

2626

P0DPF2
DSCQPYGSSFYALEE

NBPF20

3846

P0DPF2
DSCQPYGSSFYALEE

NBPF20

5066

P0DPF2
DSCQPYGSSFYALEE

NBPF26

761

B4DH59
VAGYSPDDLIGCSAY

HIF3A

261

Q9Y2N7
YSPEECLEFKAIIYG

GNAT2

61

P19087
SCVDFKPYEGESSYI

MEP1A

106

Q16819
SGEDPATCAFQRDYY

SPP2

96

Q13103
PCFYQDFSTEIPADY

SCAMP2

131

O15127
VSVGYEYETCPDFIL

TENM1

1101

Q9UKZ4
SDGFVYCPVNDATYE

WDR19

536

Q8NEZ3
YGASIVYCEPSDESR

SRR

121

Q9GZT4
AGTVLLAYYFECTDT

PLPPR1

26

Q8TBJ4
PAVSFCFCEDTDYPY

TFRC

551

P02786
LYYVGGEVYAECLSD

SMAD5

336

Q99717
LYYVGGEVYAECLSD

SMAD1

336

Q15797
LYPGCDTLDKVFTYA

ACSL3

81

O95573
FCDDQSPDAYSAYVL

CILP

811

O75339
ASPGYSDEYEEDGFC

ROR1

156

Q01973
FLGDYVDRGYFSIEC

PPP3CC

111

P48454
PGCLADYVEIYDSYD

TNFAIP6

186

P98066
LESALLGPYCFYSFS

TMEM212

96

A6NML5
IFETIYYGALEASCD

RRM1

531

P23921
LYYIGGEVFAECLSD

SMAD3

296

P84022
LDKTYFGPYDETTCI

PWP2

136

Q15269
CTAPAKYTVFDAEGY

MOSPD3

71

O75425
TGAASFLCRYPEYDG

TPP2

21

P29144
PDYYLDEAGRCTACV

TNFRSF8

246

P28908
LSEAFVSVGYEYESC

TENM4

1131

Q6N022
VSVGYEYESCPDLIL

TENM4

1136

Q6N022
DVGLDCFFYISVYPG

SEZ6

266

Q53EL9
GDPASLDFAQCLGYY

TOX3

11

O15405
LDCTYDTSDPSYGLF

TRAV14DV4

41

A0A0A6YYC5
GSEYFEKLDPYFLVC

TTC21A

446

Q8NDW8
DPILYCFVTETGRYD

GPR65

286

Q8IYL9
YAIPPDACSLDSDYS

PLEKHH1

541

Q9ULM0
ESDCFCSYFRPGIIY

VILL

101

O15195
LGACFKDAEYIYPSL

PHF8

841

Q9UPP1
SYPGTIFSCDDFYIL

PLBD2

301

Q8NHP8
YYAELGQCSVFPATD

PLK2

546

Q9NYY3
AEEFESCGTPSYFIV

WSCD2

306

Q2TBF2
YEAIYPETAAILGYC

XPC

656

Q01831
ADIYCVYPDSFSGVS

TLR5

606

O60602
YDLCVDALSPTFYFL

UBR4

2026

Q5T4S7
EFDGYYLESDPCLVC

UBR4

3521

Q5T4S7
DDEEYSCIALGEPLY

PICK1

271

Q9NRD5
YFYFGELPLSLAACT

TRPV4

281

Q9HBA0
DDVFTLDYNYPLCAV

TULP3

411

O75386
YSEYNPEVGYCRDLS

USP6

176

P35125
CEIFGYFSSEEDPIA

WDR64

91

B1ANS9
CSVYGDPRYLTFDGF

ZAN

2331

Q9Y493
LAGGYDTIFSLCDDY

KCNF1

56

Q9H3M0
LDGYSVEYCPEGCSE

MYBPC3

901

Q14896
IGCYAYDTPDFTLAE

NEB

5346

P20929