Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidase activity

PCSK1 PRSS35 PAPPA2 DPP6 PRSS12 CPA1 ADAMTS13 ST14 SCRN2 DPP9 ADAMTS6 DPEP2 ADAMTS17 ADAMTS18 PRSS42P

2.37e-0565413015GO:0008233
GeneOntologyMolecularFunctiondolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity

ALG10B ALG10

4.21e-0521302GO:0106073
GeneOntologyMolecularFunctionmetallopeptidase activity

PAPPA2 CPA1 ADAMTS13 ADAMTS6 DPEP2 ADAMTS17 ADAMTS18

3.40e-042001307GO:0008237
GeneOntologyMolecularFunctionserine-type peptidase activity

PCSK1 PRSS35 DPP6 PRSS12 ST14 DPP9 PRSS42P

4.19e-042071307GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

PCSK1 PRSS35 DPP6 PRSS12 ST14 DPP9 PRSS42P

4.83e-042121307GO:0017171
GeneOntologyMolecularFunctionendopeptidase activity

PCSK1 PRSS35 PAPPA2 PRSS12 ADAMTS13 ST14 ADAMTS6 ADAMTS17 ADAMTS18 PRSS42P

5.17e-0443013010GO:0004175
GeneOntologyMolecularFunctionexopeptidase activity

DPP6 CPA1 SCRN2 DPP9 DPEP2

7.67e-041101305GO:0008238
MousePhenobile duct inflammation

MAP3K14 PKD1 PKHD1

6.99e-0661003MP:0003254
MousePhenodecreased width of hypertrophic chondrocyte zone

INTU KDM6B XYLT1 PKD1 ADAMTS17

1.17e-05421005MP:0003409
DomainGalactose-bd-like

PCSK1 EPHB6 CNTNAP3B MANBA MYCBP2 CNTNAP3 NTNG1 GLB1

2.50e-07941278IPR008979
Domain-

PCSK1 EPHB6 MANBA MYCBP2 CNTNAP3 NTNG1 GLB1

6.39e-077312772.60.120.260
Domain-

WSB1 FBXW9 EML6 FSTL4 WDR38 EML5 PLXNC1 NLE1 WDR12 DCAF11 SEC13

1.73e-05333127112.130.10.10
DomainWD40/YVTN_repeat-like_dom

WSB1 FBXW9 EML6 FSTL4 WDR38 EML5 PLXNC1 NLE1 WDR12 DCAF11 SEC13

1.83e-0533512711IPR015943
DomainPeptidase_M12B_ADAM-TS

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.95e-05241274IPR013273
DomainG-protein_beta_WD-40_rep

WSB1 FBXW9 WDR38 NLE1 WDR12 DCAF11

2.47e-05851276IPR020472
DomainAlg10

ALG10B ALG10

4.59e-0521272IPR016900
DomainDUF2181

FAM151B FAM151A

4.59e-0521272IPR019356
DomainNLE

NLE1 WDR12

4.59e-0521272IPR012972
DomainNLE

NLE1 WDR12

4.59e-0521272PF08154
DomainDUF2181

FAM151B FAM151A

4.59e-0521272PF10223
DomainDIE2_ALG10

ALG10B ALG10

4.59e-0521272PF04922
DomainTSP_1

ADGRB1 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

6.89e-05631275PF00090
DomainWD40

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

7.05e-052591279PF00400
DomainTSP1

ADGRB1 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

8.00e-05651275SM00209
DomainTSP1_rpt

ADGRB1 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

8.00e-05651275IPR000884
DomainTSP1

ADGRB1 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

8.00e-05651275PS50092
DomainWD40

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

9.15e-052681279SM00320
DomainWD40_repeat

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

1.02e-042721279IPR001680
DomainPLAC

ADAMTS6 ADAMTS17 ADAMTS18

1.06e-04141273PF08686
DomainWD_REPEATS_1

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

1.21e-042781279PS00678
DomainWD_REPEATS_2

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

1.24e-042791279PS50082
DomainWD_REPEATS_REGION

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

1.24e-042791279PS50294
DomainWD40_repeat_CS

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12

1.31e-041641277IPR019775
DomainDISINTEGRIN_1

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.54e-04401274PS00427
DomainReprolysin

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.54e-04401274PF01421
DomainADAM_MEPRO

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.54e-04401274PS50215
DomainDISINTEGRIN_2

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.54e-04401274PS50214
DomainPeptidase_M12B

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.54e-04401274IPR001590
DomainDisintegrin_dom

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.70e-04411274IPR001762
DomainWD40_repeat_dom

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

1.98e-042971279IPR017986
Domain-

PAPPA2 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

2.28e-048112753.40.390.10
DomainMetalloPept_cat_dom

PAPPA2 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

2.28e-04811275IPR024079
DomainPLAC

ADAMTS6 ADAMTS17 ADAMTS18

2.75e-04191273PS50900
DomainPLAC

ADAMTS6 ADAMTS17 ADAMTS18

2.75e-04191273IPR010909
DomainAnaphylatoxin_comp_syst

C4A C4B

4.53e-0451272IPR018081
DomainAnaphylatoxn_comp_syst_dom

C4A C4B

4.53e-0451272IPR001840
DomainADAM_spacer1

ADAMTS6 ADAMTS17 ADAMTS18

4.92e-04231273IPR010294
DomainADAM_spacer1

ADAMTS6 ADAMTS17 ADAMTS18

4.92e-04231273PF05986
DomainZINC_PROTEASE

PAPPA2 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

5.50e-04981275PS00142
DomainPectin_lyas_fold

SHCBP1 PKHD1

6.76e-0461272IPR012334
DomainPbH1

SHCBP1 PKHD1

6.76e-0461272SM00710
Domain-

SHCBP1 PKHD1

6.76e-04612722.160.20.10
DomainHELP

EML6 EML5

6.76e-0461272PF03451
Domain-

DPP6 DPP9

6.76e-04612722.140.10.30
DomainDPPIV_N

DPP6 DPP9

6.76e-0461272PF00930
DomainHELP

EML6 EML5

6.76e-0461272IPR005108
DomainPbH1

SHCBP1 PKHD1

6.76e-0461272IPR006626
DomainPeptidase_S9B_N

DPP6 DPP9

6.76e-0461272IPR002469
DomainANATO

C4A C4B

9.42e-0471272SM00104
DomainANAPHYLATOXIN_2

C4A C4B

9.42e-0471272PS01178
DomainANAPHYLATOXIN_1

C4A C4B

9.42e-0471272PS01177
DomainANATO

C4A C4B

9.42e-0471272PF01821
DomainAnaphylatoxin/fibulin

C4A C4B

9.42e-0471272IPR000020
DomainAbhydrolase_1

SERHL2 SERHL ABHD12

1.20e-03311273PF00561
DomainMacrogloblnA2_thiol-ester-bond

C4A C4B

1.25e-0381272IPR019565
DomainPectin_lyase_fold/virulence

SHCBP1 PKHD1

1.25e-0381272IPR011050
DomainThiol-ester_cl

C4A C4B

1.25e-0381272PF10569
DomainMacrogloblnA2_CS

C4A C4B

1.25e-0381272IPR019742
DomainAB_hydrolase_1

SERHL2 SERHL ABHD12

1.44e-03331273IPR000073
Domain-

MANBA LCT GLB1

1.71e-033512733.20.20.80
DomainA2M

C4A C4B

1.99e-03101272PF00207
DomainA2M_N_2

C4A C4B

1.99e-03101272IPR011625
DomainA2M_comp

C4A C4B

1.99e-03101272IPR011626
DomainA2M_recep

C4A C4B

1.99e-03101272PF07677
DomainA2M_comp

C4A C4B

1.99e-03101272PF07678
DomainA2M_N

C4A C4B

1.99e-03101272PF01835
DomainA2M_N

C4A C4B

1.99e-03101272IPR002890
DomainA-macroglobulin_rcpt-bd

C4A C4B

1.99e-03101272IPR009048
DomainALPHA_2_MACROGLOBULIN

C4A C4B

1.99e-03101272PS00477
DomainA2M_N_2

C4A C4B

1.99e-03101272PF07703
DomainMacroglobln_a2

C4A C4B

1.99e-03101272IPR001599
DomainGlyco_hydro_catalytic_dom

MANBA LCT GLB1

2.18e-03381273IPR013781
DomainPep_M12B_propep

ADAMTS6 ADAMTS17 ADAMTS18

2.35e-03391273PF01562
DomainPeptidase_M12B_N

ADAMTS6 ADAMTS17 ADAMTS18

2.35e-03391273IPR002870
DomainPeptidase_S9

DPP6 DPP9

2.42e-03111272PF00326
DomainPeptidase_S9

DPP6 DPP9

2.42e-03111272IPR001375
DomainPept_M10_metallopeptidase

ADAMTS13 ADAMTS17 ADAMTS18

3.11e-03431273IPR001818
Domain6-blade_b-propeller_TolB-like

WSB1 LRP1B TENM4

3.77e-03461273IPR011042
DomainLDLRA_1

LRP1B ST14 PKD1

4.25e-03481273PS01209
DomainLDLRA_2

LRP1B ST14 PKD1

4.50e-03491273PS50068
DomainTRYPSIN_HIS

PRSS35 PRSS12 ST14 PRSS42P

5.37e-031031274IPR018114
DomainEGF

CNTNAP3B VASN CNTNAP3 NTNG1 LRP1B TENM4

5.44e-032351276SM00181
DomainEGF_3

CNTNAP3B VASN CNTNAP3 NTNG1 LRP1B TENM4

5.44e-032351276PS50026
Domain-

EPHB6 PAPPA2 CRLF1 MYCBP2 VASN FSTL4 DAG1 CSF3R PLXNC1 CD101 PKHD1

5.58e-03663127112.60.40.10
DomainGlycoside_hydrolase_SF

MANBA LCT GLB1

5.61e-03531273IPR017853
DomainPropept_inh

PCSK1 CPA1

5.84e-03171272IPR009020
DomainC345C

C4A C4B

5.84e-03171272SM00643
DomainTRYPSIN_SER

PRSS35 PRSS12 ST14 PRSS42P

5.94e-031061274PS00135
DomainTRYPSIN_HIS

PRSS35 PRSS12 ST14 PRSS42P

6.14e-031071274PS00134
DomainTerpenoid_cyclase/PrenylTrfase

C4A C4B

6.54e-03181272IPR008930
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

DAG1 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

6.47e-0568885M27303
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

9.87e-0539884M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

9.87e-0539884MM15165
Pubmed

Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

ADAMTS13 ADAMTS17 ADAMTS18

1.89e-067133311867212
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

UBR2 CRLF1 MANBA MYCBP2 VASN CNTNAP3 SREBF1 FSTL4 DAG1 LRP1B CDKAL1 FZD6 OLFML2A GLB1 C4A TTC17 ABHD12

3.58e-0612011331735696571
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

SCN11A VASN CD2AP ATAD2 SCRN2 EML5 GLB1 ARSF SLC15A2 FAM151A PKD1 PKHD1 GEMIN4 SAMM50 SEC13

8.52e-0610161331519056867
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADGRB1 ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

1.06e-0575133520637190
Pubmed

Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.

DAG1 CPA1 PKD1 PKHD1

1.09e-0536133425715395
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS13 ADAMTS17 ADAMTS18

1.17e-0512133325770910
Pubmed

Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.

C4A C4B

1.45e-052133222737222
Pubmed

Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.

C4A C4B

1.45e-052133216565498
Pubmed

Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.

C4A C4B

1.45e-052133215998580
Pubmed

High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.

C4A C4B

1.45e-052133219062096
Pubmed

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

C4A C4B

1.45e-052133219933335
Pubmed

Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.

C4A C4B

1.45e-05213322459207
Pubmed

Antigen-induced B cell apoptosis is independent of complement C4.

C4A C4B

1.45e-052133217645767
Pubmed

Anti-DNA autoreactivity in C4-deficient mice.

C4A C4B

1.45e-052133212207352
Pubmed

Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo.

SERHL2 SERHL

1.45e-052133211352564
Pubmed

Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.

C4A C4B

1.45e-052133227758680
Pubmed

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.

C4A C4B

1.45e-052133222387014
Pubmed

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

C4A C4B

1.45e-052133223749435
Pubmed

Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.

C4A C4B

1.45e-052133223918728
Pubmed

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.

C4A C4B

1.45e-05213323037333
Pubmed

Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.

C4A C4B

1.45e-052133211726230
Pubmed

Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.

C4A C4B

1.45e-05213324216347
Pubmed

Sequence determination of the thiolester site of the fourth component of human complement.

C4A C4B

1.45e-05213326950384
Pubmed

Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.

C4A C4B

1.45e-05213328660986
Pubmed

Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.

C4A C4B

1.45e-05213328428773
Pubmed

Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.

C4A C4B

1.45e-052133224638111
Pubmed

Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.

HDAC6 PKD1

1.45e-052133228887310
Pubmed

Transcriptional repression of C4 complement by hepatitis C virus proteins.

C4A C4B

1.45e-052133221345967
Pubmed

Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.

C4A C4B

1.45e-05213322572548
Pubmed

The complement component C4 of mammals.

C4A C4B

1.45e-05213322302180
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

1.45e-052133226807827
Pubmed

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.

C4A C4B

1.45e-052133222151770
Pubmed

C4d-positive chronic rejection: a frequent entity with a poor outcome.

C4A C4B

1.45e-052133218091514
Pubmed

Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.

C4A C4B

1.45e-052133229080553
Pubmed

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

C4A C4B

1.45e-05213326589636
Pubmed

JmjC-KDMs KDM3A and KDM6B modulate radioresistance under hypoxic conditions in esophageal squamous cell carcinoma.

KDM3A KDM6B

1.45e-052133233318475
Pubmed

C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.

C4A C4B

1.45e-052133225339671
Pubmed

A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.

C4A C4B

1.45e-052133217728371
Pubmed

Structure and organization of the C4 genes.

C4A C4B

1.45e-05213326149580
Pubmed

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.

C4A C4B

1.45e-05213326149581
Pubmed

The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.

C4A C4B

1.45e-052133212115608
Pubmed

Biochemistry and biology of anaphylatoxins.

C4A C4B

1.45e-05213323542363
Pubmed

C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.

C4A C4B

1.45e-05213322387317
Pubmed

Cell-specific role of histone deacetylase 6 in chemotherapy-induced mechanical allodynia and loss of intraepidermal nerve fibers.

RAG2 HDAC6

1.45e-052133231356453
Pubmed

Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.

C4A C4B

1.45e-052133216908004
Pubmed

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein.

PKD1 PKHD1

1.45e-052133211919560
Pubmed

Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.

C4A C4B

1.45e-05213327365238
Pubmed

Replication the association of 2q32.2-q32.3 and 14q32.11 with hepatocellular carcinoma.

EFCAB11 STAT4

1.45e-052133225665738
Pubmed

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

C4A C4B

1.45e-05213327391573
Pubmed

Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.

C4A C4B

1.45e-052133217971360
Pubmed

Clinical features of patients with homozygous complement C4A or C4B deficiency.

C4A C4B

1.45e-052133229928053
Pubmed

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.

C4A C4B

1.45e-052133217971229
Pubmed

Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.

C4A C4B

1.45e-05213326881182
Pubmed

Partial C4 deficiency in juvenile idiopathic arthritis patients.

C4A C4B

1.45e-052133217921792
Pubmed

Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.

C4A C4B

1.45e-052133221880985
Pubmed

Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.

C4A C4B

1.45e-05213326978711
Pubmed

Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.

C4A C4B

1.45e-052133235898513
Pubmed

Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.

C4A C4B

1.45e-052133228873507
Pubmed

Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.

C4A C4B

1.45e-0521332276882
Pubmed

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.

C4A C4B

1.45e-05213326832377
Pubmed

Association of polymorphisms in the haplotype block spanning the alternatively spliced exons of the NTNG1 gene at 1p13.3 with schizophrenia in Japanese populations.

NTNG1 OGG1

1.45e-052133218384956
Pubmed

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.

C4A C4B

1.45e-05213323794341
Pubmed

Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.

C4A C4B

1.45e-052133222785613
Pubmed

Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.

C4A C4B

1.45e-052133232691186
Pubmed

The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.

C4A C4B

1.45e-05213328390682
Pubmed

Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).

C4A C4B

1.45e-05213323902619
Pubmed

Structural polymorphism of murine C4 and its linkage to H-2.

C4A C4B

1.45e-05213327373044
Pubmed

The chemical structure of the C4d fragment of the human complement component C4.

C4A C4B

1.45e-05213323696167
Pubmed

Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.

C4A C4B

1.45e-05213321357031
Pubmed

Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.

C4A C4B

1.45e-052133216098595
Pubmed

The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.

CNTNAP3B CNTNAP3

1.45e-052133231150793
Pubmed

Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.

C4A C4B

1.45e-052133215787745
Pubmed

Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

C4A C4B

1.45e-052133230026462
Pubmed

A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.

C4A C4B

1.45e-05213326559257
Pubmed

Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.

C4A C4B

1.45e-052133234299197
Pubmed

Assessment of complement C4 gene copy number using the paralog ratio test.

C4A C4B

1.45e-052133220506482
Pubmed

Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.

C4A C4B

1.45e-052133212480675
Pubmed

Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.

C4A C4B

1.45e-052133226800705
Pubmed

Murine complement C4 is not required for experimental autoimmune encephalomyelitis.

C4A C4B

1.45e-052133215390104
Pubmed

Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.

C4A C4B

1.45e-05213321699796
Pubmed

Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.

C4A C4B

1.45e-05213322997024
Pubmed

Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.

C4A C4B

1.45e-05213323624865
Pubmed

Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.

C4A C4B

1.45e-052133221857912
Pubmed

Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.

C4A C4B

1.45e-05213326208559
Pubmed

The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.

C4A C4B

1.45e-05213324514997
Pubmed

The inheritance of susceptibility to the Gross leukemia virus in mice.

C4A C4B

1.45e-05213325919331
Pubmed

An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.

C4A C4B

1.45e-05213323167981
Pubmed

Pathogenicity analysis of novel variations in Chinese Han patients with polycystic kidney disease.

PKD1 PKHD1

1.45e-052133228578020
Pubmed

The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.

C4A C4B

1.45e-05213327545960
Pubmed

Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.

C4A C4B

1.45e-052133230041577
Pubmed

Complete cDNA sequence of the fourth component of murine complement.

C4A C4B

1.45e-05213323862104
Pubmed

The BS variant of C4 protects against age-related loss of white matter microstructural integrity.

C4A C4B

1.45e-052133234358307
Pubmed

Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.

C4A C4B

1.45e-052133218360261
Pubmed

Schizophrenia risk from complex variation of complement component 4.

C4A C4B

1.45e-052133226814963
Pubmed

NF-κB-inducing kinase contributes to normal development of cortical thymic epithelial cells: its possible role in shaping a proper T-cell repertoire.

RAG2 MAP3K14

1.45e-052133232145062
Pubmed

Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.

C4A C4B

1.45e-05213328132550
Pubmed

Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.

C4A C4B

1.45e-05213322395880
Pubmed

Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.

C4A C4B

1.45e-052133226814708
Pubmed

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).

C4A C4B

1.45e-05213326192448
Pubmed

Complete primary structure of human C4a anaphylatoxin.

C4A C4B

1.45e-05213326167582
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS13 ADAMTS6 ADAMTS17 ADAMTS18

2.30e-061992450
GeneFamilyWD repeat domain containing

WSB1 FBXW9 EML6 WDR38 EML5 NLE1 WDR12 DCAF11 SEC13

7.48e-06262929362
GeneFamilyAlpha-1,2-glucosyltransferases

ALG10B ALG10

2.56e-052922448
GeneFamilyProteases, serine

PRSS35 PRSS12 ST14 PRSS42P

2.97e-0463924738
GeneFamilyCD molecules|DASH family

DPP6 DPP9

5.29e-0479221205
GeneFamilyC3 and PZP like, alpha-2-macroglobulin domain containing

C4A C4B

9.01e-0499221234
CoexpressionGSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_DN

PCSK1 EPHB6 PRSS12 LCT GLB1 CSF3R CD101 SEC13

7.76e-061971338M8339
CoexpressionGSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN

BAZ2B TTC27 LCT STAT4 FZD6 XYLT1 GLB1 UGDH

8.66e-062001338M8027
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PAPPA2 WSB1 LRP1B SLC16A5 ADAMTS17 PKHD1 ABTB2

9.64e-08187133877886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PAPPA2 WSB1 CD2AP LRP1B ADAMTS17 PKHD1 ABTB2

9.64e-081871338f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

TRPM6 PAPPA2 MMS22L FSTL4 LRP1B ARHGAP6 ADAMTS17 PKHD1

1.00e-071881338df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 PAPPA2 WSB1 CD2AP LRP1B ADAMTS17 PKHD1 ABTB2

1.05e-071891338e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBR2 MMS22L MYCBP2 CDKAL1 CCNT2 ALG10 TTC17 EDRF1

1.13e-0719113389454f642c3621370fa23640b631301346b300950
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 EML6 SLC16A5 FAM151A C4A C4B

4.17e-07951336a09443e527d37adb637a66ca857525dab1c39a9b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK1 EPHB6 FSTL4 LRP1B FZD6 TENM4 DNAH6

1.14e-061791337b35a7f8115c997c390201da01d7cb10b10769aec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 WSB1 CD2AP EML6 FSTL4 SHCBP1 ABTB2

1.19e-061801337788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB6 RAG2 HBP1 KDM6B SLC16A5 EIF4E3 ABTB2

1.64e-061891337a1773ef8fe4518d8f3b17c6fb2c3ff3bbc4d79ad
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 WSB1 CD2AP FSTL4 LRP1B PKHD1 ABTB2

1.64e-06189133790aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 WSB1 CD2AP FSTL4 LRP1B PKHD1 ABTB2

1.70e-0619013374836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PAPPA2 DPP6 CNTNAP3 NTNG1 LRP1B ADAMTS17 ADAMTS18

1.76e-061911337156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

PAPPA2 LRP1B ARFGEF3 ARHGAP6 TENM4 SLC16A5 PKHD1

2.09e-06196133704f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-6|TCGA-Stomach / Sample_Type by Project: Shred V9

PAPPA2 TTI2 FSTL4 DNAJC6 TTC17

1.08e-05971335489f5e12eb67b1850f1f2d7d4b229df1f4ceefe3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B TRANK1 OTOGL PKHD1 C4B DNAH6

1.19e-05169133612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB6 MMS22L ATAD2 RCC2 XYLT1 RASAL3

1.36e-051731336de124fb7ded04664d4184bf12f1f201c0784f07c
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 CRLF1 MANBA PRSS12 ADAMTS6 C4B

1.65e-051791336e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRN2 RASAL3 SLC16A5 PKHD1 DNAH6 ABHD12

1.75e-05181133641969fe4d94ee77b12ecde32170aaf0b13e49644
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCRN2 RASAL3 SLC16A5 PKHD1 DNAH6 ABHD12

1.75e-0518113363f50e61dc2a52d71a5801584617607e6246adcf2
ToppCelldroplet-Lung-nan-21m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 CRLF1 ST14 ARFGEF3 WDR38 SLC15A2

1.81e-05182133640539ade8c3cd12b61f1cd0d493828e58282796b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B ARFGEF3 TRANK1 TENM4 OTOGL PKHD1

1.92e-0518413362cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B ARFGEF3 TRANK1 TENM4 OTOGL PKHD1

1.92e-051841336ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B ARFGEF3 TRANK1 TENM4 OTOGL PKHD1

1.92e-0518413362b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

UBR2 MMS22L MYCBP2 CDKAL1 CCNT2 TTC17

1.98e-051851336a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 WSB1 CD2AP FSTL4 LRP1B ABTB2

2.04e-051861336d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 WSB1 FSTL4 LRP1B SHCBP1 ABTB2

2.04e-05186133608632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

BAZ2B LRP1B TENM4 CSF3R OTOGL PKHD1

2.04e-05186133623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

UBR2 MMS22L MYCBP2 CDKAL1 CCNT2 TTC17

2.04e-0518613368571956890fc9894d766ba294a28e376b4aba428
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Parm1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PAPPA2 PRSS12 NTNG1 XYLT1 ADAMTS18

2.09e-0511113351847dde68d349114286bc3317be6339666df4aa2
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST14 STAT4 OLFML2A SLC15A2 PKHD1 ABTB2

2.17e-051881336842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST14 STAT4 OLFML2A SLC15A2 PKHD1 ABTB2

2.17e-051881336a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 CD2AP EML6 FSTL4 PKHD1 ABTB2

2.24e-0518913368ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 FSTL4 LRP1B ARHGAP6 ADAMTS17 PKHD1

2.24e-051891336975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD2AP LRP1B ARHGAP6 SLC16A5 PKHD1 ABTB2

2.37e-0519113363e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAPPA2 LRP1B ARHGAP6 TENM4 PKHD1 ABTB2

2.37e-051911336fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell11.5-Airway-Epithelial-Bud_tip_adjacent|Airway / Age, Tissue, Lineage and Cell class

CRLF1 TMEM54 ST14 FZD6 PKHD1 GPRIN2

2.44e-051921336fbb34a959b9bd9cb72a5195a07f4653a957e4ca8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD2AP LRP1B ARHGAP6 SLC16A5 PKHD1 ABTB2

2.59e-05194133604bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 CD2AP MAP3K14 LRP1B PKHD1 ABTB2

2.59e-05194133646070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 CD2AP MAP3K14 LRP1B PKHD1 ABTB2

2.59e-051941336abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CRLF1 TMEM54 ST14 FZD6 ARFGEF3 PKHD1

2.59e-051941336c011cd59bb4ca4134331cba0f5d73bdbd7011d64
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CD2AP LRP1B ARHGAP6 SLC16A5 PKHD1 ABTB2

2.59e-05194133669bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellmild-Myeloid-Neutrophils_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

BAZ2B CNTNAP3 KDM6B CSF3R PLXNC1 DPEP2

2.59e-051941336ccd911ce3251cd1c60f1fb2ce00650fbe7a379bb
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WSB1 CRLF1 DAG1 HBP1 OLFML2A TENM4

2.82e-0519713365bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DISC1 STAT4 RASAL3 CSF3R PLXNC1 DPEP2

2.82e-0519713360523aec9713ae21e6b879aa98e07fa2576610d5f
ToppCellControl-Control-Myeloid-Neutrophil|Control / Disease, condition lineage and cell class

UBR2 BAZ2B CNTNAP3 TRANK1 CSF3R PLXNC1

3.07e-05200133695c41f147a1594d49e73cb56d86d301c3115ce20
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

DPP6 CD2AP EML5 SLC15A2 PKHD1 ALDH4A1

3.07e-0520013362dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E-|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 FSTL4 LRP1B FZD6 TENM4 DNAH6

3.07e-0520013361a3d29a580d1b405a74869a1da3e818c581fc559
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E---L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 FSTL4 LRP1B FZD6 TENM4 DNAH6

3.07e-0520013366f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E--|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 FSTL4 LRP1B FZD6 TENM4 DNAH6

3.07e-05200133686705dfc05b3e1576543b93883c88fb55b742855
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E|Neuronal / cells hierarchy compared to all cells using T-Statistic

PCSK1 FSTL4 LRP1B FZD6 TENM4 DNAH6

3.07e-052001336db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 GLB1 SLC16A5 C4A C4B

3.42e-051231335a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCellEntopeduncular-Macroglia-ASTROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PRSS35 ANKRD66 BIRC7 SLC15A2 ACSS3

4.29e-051291335c37bdd6c0b2944fbfa064922954ea0e263160e2a
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PRSS35 ANKRD66 BIRC7 SLC15A2 ACSS3

4.29e-0512913358648ae59f7aca0f5b4983bdb4a65b03b2ca761e1
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Gabra5)|Hippocampus / BrainAtlas - Mouse McCarroll V32

PAPPA2 OTOGL ADAMTS18 ZNF541

6.43e-05721334480653f8bd0ef118cb8d541103692e3ec8a1b58d
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1B OTOGL MYLK4 PKHD1 GPRIN2

7.49e-05145133596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAP3K14 FAM151B PLXNC1 STARD9 GEMIN4

8.79e-0515013357a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L TMEM54 ATAD2 SLC15A2 ADAMTS18

1.06e-041561335b28bbdb515317368f1231b0b15d7442352f3b400
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LRP1B ARFGEF3 ARHGAP6 ADAMTS17

1.23e-0416113354bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

PRSS35 CNTNAP3B CNTNAP3 RASAL3 STARD9

1.23e-041611335b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

CNTNAP3B CNTNAP3 CSF3R PLXNC1 ACSS3

1.23e-04161133598c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK1 LRP1B OTOGL MYLK4 PKHD1

1.26e-041621335bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellwk_20-22-Hematologic-Myeloid-GMP|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RCC2 CSF3R SHCBP1 PRRT3 FUT4

1.41e-041661335d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCellPND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBXW9 TMEM54 DNAJC6 MLH1 ADAMTS18

1.45e-04167133529d271643f3a1718b53db77b7d093ec94225a824
ToppCellPND14-Immune-Immune_Myeloid-Dendritic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L EFCAB11 ATAD2 DPEP2 SHCBP1

1.49e-0416813359b8a74abb83c64f0b5829dcb4275f722c82b45dc
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L EFCAB11 ATAD2 DPEP2 SHCBP1

1.49e-0416813354b152b8d0f4a66faf664dfacb7914b18d60ce64a
ToppCellPND14-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L EFCAB11 ATAD2 DPEP2 SHCBP1

1.49e-041681335c3169ad8f4130ef18777ed86770bb722ffb5db85
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

CNTNAP3B CNTNAP3 CSF3R PLXNC1 ACSS3

1.54e-0416913356e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TRPM6 CNTNAP3 ATAD2 PLXNC1 FUT4

1.58e-041701335cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRB1 LRP1B OTOGL PLXNC1 ADAMTS18

1.58e-0417013355570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZMYND19 MANBA DISC1 EML6 XYLT1

1.67e-041721335eba1568d4307e91c94fc616549057cbed8df5840
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 XYLT1 SCRN2 RASAL3 EML5

1.71e-0417313356e92983d9f8a2a37f23e60a0d5bb1738217897bc
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CNTNAP3 LRP1B OTOGL CD101 ADAMTS17

1.71e-041731335b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK1 XYLT1 SCRN2 RASAL3 EML5

1.71e-0417313354c788c1dad1da495b3b5c10f95e779848dfe85dc
ToppCellsevere_influenza-Neutrophil|World / disease group, cell group and cell class (v2)

CNTNAP3B CNTNAP3 CSF3R PLXNC1 ACSS3

1.76e-041741335f9f07436b7d3f190800cd85d229f007032f391e1
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 EML6 FAM151A C4B

1.81e-0494133400b932421d77f0fd8d6ffe439c992ebc95ad7c94
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPP6 SCN11A EML6 DNAJC6 EML5

1.86e-04176133504dad262929581872e5bbc66cd8182c963e7e52f
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAJC6 XYLT1 RNF123 DOCK6 GPRIN2

1.91e-041771335a235ff4f37a7622216526191efc4832fb8ed6957
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCSK1 TMEM54 SREBF1 FUT4 GPRIN2

1.91e-04177133543dce527392f3b8364bb6a55268ce9d6518d3a29
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CRLF1 ANKRD66 WDR38 DNAI7 DNAH6

2.01e-0417913350e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRSS35 ADGRB1 ATAD2 TENM4 ZNF541

2.01e-041791335ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB1 NTNG1 OGG1 ALG10B OLFML2A

2.01e-041791335c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTNAP3B EML6 FSTL4 SHCBP1 ABTB2

2.06e-041801335023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell18-Airway-Epithelial-Submucosal_gland_basal|Airway / Age, Tissue, Lineage and Cell class

ADGRB1 ST14 ADAMTS17 ADAMTS18 ABTB2

2.11e-04181133533938e6521712058312879f84f4ae381c2bfc379
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPP6 DNAJC6 XYLT1 ARFGEF3 EML5

2.11e-0418113357f99002a6411117cc2361334c7c9228e20c574b4
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG2 KDM6B SLC16A5 WDR12 EIF4E3

2.22e-0418313356a15ffb56381b724ef4d574e7b2835e00e1a0092
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WSB1 EML6 FSTL4 SHCBP1 ABTB2

2.22e-041831335d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MANBA TMEM54 ARFGEF3 SLC16A5 DPEP2

2.22e-0418313357eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAG2 KDM6B SLC16A5 WDR12 EIF4E3

2.28e-041841335b80d3f2b76927842a54bc89a87cd70469a6d825a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 LRP1B ARHGAP6 TENM4 ADAMTS17

2.28e-041841335e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM54 FSTL4 ST14 SLC15A2 ADAMTS18

2.28e-041841335e93633d89a9c54c8d2819f56372815b4ca149f06
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK1 FSTL4 LRP1B TENM4 DNAH6

2.28e-0418413359cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCellCOPD-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

NTNG1 UGDH ADAMTS17 C4A C4B

2.34e-04185133523579988036fc1925992c31919750f9b3fe9f790
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WSB1 KDM6B CSF3R DPEP2 PKHD1

2.34e-04185133542690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MANBA KDM6B STAT4 XYLT1 ABTB2

2.34e-041851335a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CNTNAP3B CNTNAP3 ARHGAP6 SLC15A2 ADAMTS17

2.40e-041861335948815663c212c4311329d503b5991cbbbff9808
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 LCT ST14 ARFGEF3 PKHD1

2.40e-0418613353c4994a1a7db06a61da8170e45e06aaef7896592
ToppCellfacs-Lung-EPCAM-24m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 LCT ST14 ARFGEF3 PKHD1

2.40e-041861335a583d6fc0f1e729f6e9fd18d7b49d6eab9ca32b9
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Proliferative_AT2_Progenitor|E16.5-samps / Age Group, Lineage, Cell class and subclass

CRLF1 FSTL4 SCRN2 SLC15A2 ADAMTS18

2.46e-041871335e986901f5a1e09cbc9ba37e3c62845ff90ceda95
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CRLF1 ANKRD66 WDR38 DNAI7 DNAH6

2.46e-0418713352b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellCOVID-19-kidney-Mito-rich_Distal|kidney / Disease (COVID-19 only), tissue and cell type

PAPPA2 LRP1B ARHGAP6 TENM4 PKHD1

2.46e-0418713352ce8038d9d1302e850c1bb536e755598f77ba4b9
Disease3-(3-amino-3-carboxypropyl)uridine measurement

ATAD2 ZHX1

1.90e-0521292EFO_0800632
DiseaseDepression, Bipolar

DISC1 NTNG1 TRANK1 TENM4 STARD9

2.57e-05791295C0005587
DiseaseLong Qt Syndrome 2

ALG10B ALG10

5.67e-0531292C3150943
DiseaseManic Disorder

NTNG1 TRANK1 TENM4 STARD9

2.70e-04711294C0024713
Diseasenonsyndromic deafness (implicated_via_orthology)

ALG10B ALG10

2.81e-0461292DOID:0050563 (implicated_via_orthology)
DiseaseManic

NTNG1 TRANK1 TENM4 STARD9

3.87e-04781294C0338831
Diseasepolycystic liver disease (implicated_via_orthology)

HDAC6 PKD1

3.93e-0471292DOID:0050770 (implicated_via_orthology)
DiseaseDevelopmental Coordination Disorder

DISC1 OGG1

5.22e-0481292C0011757
Diseaseosteosarcoma

ADAMTS6 ADAMTS17

5.22e-0481292EFO_0000637
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3

5.22e-0481292DOID:0060308 (implicated_via_orthology)
DiseaseMotor Skills Disorders

DISC1 OGG1

5.22e-0481292C0026613
DiseaseGraves' disease (is_implicated_in)

OGG1 C4A C4B

6.65e-04391293DOID:12361 (is_implicated_in)
DiseaseLymphoma

OGG1 CSF3R MLH1

7.17e-04401293C0024299
Diseasehepatocellular carcinoma

EFCAB11 STAT4 GLB1

7.71e-04411293EFO_0000182
Diseasewaist-hip ratio

PAPPA2 MMS22L MYCBP2 VASN MAP3K14 DAG1 CPA1 CDKAL1 OLFML2A WDR38 RNF123 ADAMTS6 PKD1 DOCK6

9.69e-04122612914EFO_0004343
Diseasecysteine-glutathione disulfide measurement

SERHL FSTL4

1.02e-03111292EFO_0021001
Diseaselip morphology measurement

DPP6 HDAC6 DISC1 FSTL4 XYLT1

1.48e-031891295EFO_0007845
Diseaseserum alanine aminotransferase measurement

EFCAB11 MANBA DISC1 CD2AP NTNG1 XYLT1 TRANK1 TENM4 MLH1 ADAMTS18 SAMM50

1.54e-0386912911EFO_0004735
Diseaselysophosphatidylcholine 15:0 measurement

LRP1B PKHD1

1.67e-03141292EFO_0020941
Diseasepolycystic kidney disease (implicated_via_orthology)

HDAC6 PKD1

1.67e-03141292DOID:0080322 (implicated_via_orthology)
Diseasediffuse plaque measurement

FSTL4 DNAJC6 LRP1B CDKAL1 XYLT1 ARFGEF3 TENM4 PLXNC1 MYLK4 ADAMTS18

1.87e-0375812910EFO_0010699
DiseaseBody Weight

PCSK1 CDKAL1

1.92e-03151292C0005910
Diseasethird ventricle volume measurement

HPS6 ABTB2

1.92e-03151292EFO_0010335
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

PKD1 PKHD1

2.19e-03161292DOID:0110861 (implicated_via_orthology)
Diseaserenal cell carcinoma (is_marker_for)

ADGRB1 KDM6B ST14 MLH1

2.45e-031281294DOID:4450 (is_marker_for)
Diseaseretinopathy

KLHL22 TENM4

2.47e-03171292EFO_0003839
DiseaseSjogren's syndrome (implicated_via_orthology)

MAP3K14 ST14

2.47e-03171292DOID:12894 (implicated_via_orthology)
Diseasesystemic lupus erythematosus (is_implicated_in)

STAT4 C4A C4B

2.56e-03621293DOID:9074 (is_implicated_in)
Diseaseobesity (implicated_via_orthology)

PCSK1 KDM3A HDAC6 STAT4 SLC15A2

2.60e-032151295DOID:9970 (implicated_via_orthology)
Diseasemyelodysplastic syndrome (is_marker_for)

DDX42 CSF3R

3.42e-03201292DOID:0050908 (is_marker_for)
Diseaseblood aluminium measurement

DPP6 BAZ2B

3.42e-03201292EFO_0007575
Diseaserenal cell carcinoma (is_implicated_in)

OGG1 C4A C4B

3.47e-03691293DOID:4450 (is_implicated_in)
DiseaseNon-alcoholic Fatty Liver Disease

RAG2 SREBF1 ALDH4A1

3.61e-03701293C0400966
DiseaseNonalcoholic Steatohepatitis

RAG2 SREBF1 ALDH4A1

3.61e-03701293C3241937
DiseaseLupus Erythematosus, Systemic

STAT4 C4A C4B

3.76e-03711293C0024141
Diseasekidney disease (biomarker_via_orthology)

SREBF1 XYLT1

3.77e-03211292DOID:557 (biomarker_via_orthology)
Diseasemigraine disorder, endometriosis

DPP6 FSTL4 LRP1B

4.06e-03731293EFO_0001065, MONDO_0005277
Diseasebrain infarction, neuritic plaque measurement, Lewy body dementia, cerebral amyloid angiopathy, neurofibrillary tangles measurement

CDKAL1 ABTB2

4.14e-03221292EFO_0004277, EFO_0006790, EFO_0006792, EFO_0006797, EFO_0006798

Protein segments in the cluster

PeptideGeneStartEntry
VRWIPKDDSGSVWKA

ARSF

456

P54793
AADKWLTGLAEWHVP

AADAT

336

Q8N5Z0
WSNWEIPVSTDGKHW

CCNT2

206

O60583
TPLSWWVGRTNETHT

CNTNAP3

696

Q9BZ76
GVWIPVSLHRPWESS

ERVK13-1

256

Q9NX77
TLWLPDSLTTWEIHG

C4B

796

P0C0L5
WESLRKAHGTPTWVK

ADGRB1

1531

O14514
PGAEWWRTTDAHTRT

BAZ2B

111

Q9UIF8
AIWIDTGIHSREWVT

CPA1

171

P15085
DWNDRTPLHWAAIKG

ANKRD66

41

B4E2M5
LQSWKRGDDPWTEHA

BIRC7

131

Q96CA5
SIGVPWTLHTWLESL

BTBD11

816

A6QL63
PWTGAGLRWKHTSSL

ALDH4A1

16

P30038
VKPAIWIFAWSEHVV

ALG10B

76

Q5I7T1
HIHVWWEIVGPTLKA

ATAD2

861

Q6PL18
IHLISKETGEAGWWR

CD2AP

296

Q9Y5K6
VTSSEVWKRWKHLDP

LINC00313

31

P59037
GDAHSWDTLLRKWEP

DISC1

321

Q9NRI5
ELTPIAAVHGRWSSW

ADAMTS13

376

Q76LX8
KPQDSLFIWTHSGWE

ADAMTS17

796

Q8TE56
RPIHGQWSAWSKWSE

ADAMTS18

586

Q8TE60
HCGVSDFTRSGKPWW

ADAMTS6

206

Q9UKP5
AWTIDWPRKFDVAGT

ADAMTS6

771

Q9UKP5
DWTPDIKHSKIWFGS

RAG2

306

P55895
HSLLITTEGKLWSWG

RCC2

161

Q9P258
REETWLSVWVHEAKG

RASAL3

301

Q86YV0
VTIGVWHTVPAVWWK

ABHD12

136

Q8N2K0
TLGTKRNSTHEGWVW

FBXW9

216

Q5XUX1
GWPWQVSLRLKSSHG

PRSS12

641

P56730
LRPKHAWAVSAAGWV

P2RY11

141

Q96G91
IAVHPEKGLLFWTEW

LRP1B

2001

Q9NZR2
GTRDIHPAVWDSVNW

EDRF1

951

Q3B7T1
DPLGFSWWIITHVAS

MMS22L

346

Q6ZRQ5
SRKQGLVAWVVSHWD

FUT4

351

P22083
LTKPGLWSTLHGDAW

KDM6B

276

O15054
TGWLDHWGQPHSTIK

GLB1

271

P16278
VSAAGKEALPSWLHW

DAG1

96

Q14118
EILHSGPSKWNWLTR

DDX42

476

Q86XP3
VHIWKTNSLPLRFWV

PLXNC1

1406

O60486
AWRKLWPSVAFAEGS

JRK

381

O75564
WHPFEEKIVSSSWDG

DCAF11

491

Q8TEB1
VTFSLGWTTGWHPEK

FAM151B

161

Q6UXP7
KSWRISASEALKHPW

MYLK4

346

Q86YV6
GDRVKLWVTFHEPWV

LCT

531

P09848
RWREQSPAHWSGVLA

OGG1

46

O15527
TGWHPDSAAVLWRRV

RALGAPA2

921

Q2PPJ7
GVPLHSSWTFWLDRS

EIF4E3

46

Q8N5X7
VGIIHQTKWSWRRTG

INTU

186

Q9ULD6
PFDIWGTWHSTLKSG

ARHGAP6

731

O43182
TWPWDKDAVTHLGGI

PAPPA2

701

Q9BXP8
EQKAVWFHAVAWGTP

FZD6

321

O60353
DHKWIISDGPVDALW

DNAH6

1831

Q9C0G6
AGGAESPLSVSWWHI

CD101

436

Q93033
NTWHTLADGPVRRAW

KLHL22

471

Q53GT1
WPWLSGTIRAVSHTD

KDM3A

41

Q9Y4C1
GNPENVRWRKSVTHW

DOCK6

1346

Q96HP0
KWTKPARAGSEVEWT

C2CD2L

321

O14523
PVSWWQGSGKRLSHR

C18orf15

51

Q96N68
SGEWEVLARHGSKIW

DPP9

491

Q86TI2
LLHWPVWVGAKISHG

FAM151A

436

Q8WW52
PGIQKIWIRTWGCSH

CDKAL1

61

Q5VV42
PVSNADWVWLVKRLH

ARFGEF3

1891

Q5TH69
VWVLSWGDVHKSRPS

FSTL4

556

Q6MZW2
HTVLWAGETKWKPVG

DNAJC6

841

O75061
PVVVRWDAEGKHWRT

DNAI7

451

Q6TDU7
GHWSDWSPSLELRTT

CSF3R

316

Q99062
ISKNITVETWWPHGH

MANBA

281

O00462
HWTAKLPAKWSVSES

DPEP2

451

Q9H4A9
SWPSTVWHCFLKGTR

HBP1

206

O60381
SVGLDPEHTITIWRW

EML5

1486

Q05BV3
PEHTITIWRWQEGAK

EML5

1491

Q05BV3
HTITVWRWQEGAKVA

EML6

1486

Q6ZMW3
GRFWPHLKASNWSTT

HDAC6

281

Q9UBN7
EILKTHIAHWWSPDG

DPP6

296

P42658
KARPSAGGHWWSSTV

GPRIN2

81

O60269
ATTWPGVAHVLLIWS

HPS6

206

Q86YV9
SKKAGIWSEWSHPTA

CRLF1

321

O75462
RTWEASPSEHRKWVE

EFCAB11

11

Q9BUY7
SFPIWKTSHTVKWEG

SAMM50

216

Q9Y512
AVPWGHIAAKAWGSL

SERHL2

16

Q9H4I8
SGDIPKRQHWLDWAA

SLC15A2

271

Q16348
SLKISWNPWRHGLSS

PRRT3

911

Q5FWE3
TLWLPDSLTTWEIHG

C4A

796

P0C0L4
TPLSWWVGRTNETHT

CNTNAP3B

696

Q96NU0
WDRKTTIHIKVGPQW

OTOGL

1056

Q3ZCN5
HWWEQPGVEARTLLK

P2RX6

301

O15547
ATPHSLGSVWKIRVW

PKD1

3171

P98161
TPWKWRGHSDIDFAV

OLFML2A

511

Q68BL7
LAPDGSFAWSWRVKH

MAP3K14

926

Q99558
GRHPSTFWQSATWKE

NTNG1

111

Q9Y2I2
AVPWGHIAAKAWGSL

SERHL

16

Q9NQF3
HSDWVRDVAWAPSIG

SEC13

211

P55735
RHWVLSISWSPDGRK

NLE1

156

Q9NVX2
AGHSKWITGLSWEPL

NLE1

196

Q9NVX2
HAVILSRPSWLWGAE

SCRN2

71

Q96FV2
PDSVSSWHLKRWTKV

EPHB6

141

O15197
RGESHWWMKGSTPTQ

MYCBP2

4156

O75592
HVWTLSWSTQIGDLP

PKHD1

846

P08F94
LEKVLEPSGWRAVWH

SHCBP1

106

Q8NEM2
EPSGWRAVWHTNVFK

SHCBP1

111

Q8NEM2
TATKADHWSQGWAPL

STARD9

1661

Q9P2P6
GSIPNSWKWTVEHIV

MLH1

706

P40692
REHEWIVKLASGSWI

SOWAHB

596

A6NEL2
PVAKWWASLTAVVIH

SREBF1

871

P36956
VPWKLHIWIESLRTS

ABTB2

741

Q8N961
IKPAIWIFGWSEHVV

ALG10

76

Q5BKT4
RVPVLDHWWQTETGS

ACSS3

441

Q9H6R3
FPLTSHWWAALGISK

TMEM244

111

Q5VVB8
HWVPREKILTTNTWS

UGDH

201

O60701
WGWRPKAEETSSKQR

ZMYND19

106

Q96E35
LRPGVWTVKILHHWV

XYLT1

816

Q86Y38
THQLLELRPWWGKSS

TMEM54

181

Q969K7
SHSLRKIWTVGIPPW

TRPM6

196

Q9BX84
ASSRTSHEWLLWPKA

SLC16A5

476

O15375
KHVFSWTLQQVTRPW

TTI2

226

Q6NXR4
LPRGWNWVDVVKHLS

RWDD4

166

Q6NW29
TWWPHCSSREGKEST

RNF123

456

Q5XPI4
EHLPGKSFTFWTWLE

STAT4

541

Q14765
WTRVKNTHIPKGWAR

PRSS35

251

Q8N3Z0
SHVFPAGKAIWVTGW

ST14

736

Q9Y5Y6
WFSAQRLKHGVSWTP

ZHX1

331

Q9UKY1
WPWQVSVRTKGRHIC

PRSS42P

91

Q7Z5A4
GRWTSPDHELWKHLS

TENM4

2426

Q6N022
TWLLVLVSSHVTWGP

PIGZ

186

Q86VD9
EFKSWWPATSHIIGK

MARS2

296

Q96GW9
SVKSSPVAHSILWIW

TTC17

471

Q96AE7
PVAHSILWIWGRDSD

TTC17

476

Q96AE7
LSWFGPWVRESHVTL

VASN

306

Q6EMK4
LASGSWDKTIHIWKP

WDR38

206

Q5JTN6
TSVPKTLGVRHDWTW

SCN11A

901

Q9UI33
HTGWVTSVKWSPTHE

WDR12

341

Q9GZL7
WSQGHRTVKLVPWSQ

WSB1

51

Q9Y6I7
DCDWRWDPVHTKGSI

TRANK1

2601

O15050
VRHKLTAIQSLPWWT

TTC27

171

Q6P3X3
TGSALKEIPSGWHLW

UBR2

1491

Q8IWV8
KEIPSGWHLWRSVRA

UBR2

1496

Q8IWV8
RPKASWDLWSVHFTQ

UHRF1BP1

686

Q6BDS2
WVLQDRVLSSSHPWG

SIGLEC16

271

A6NMB1
TDEHVASLVWKPWGD

ZNF541

1076

Q9H0D2
TFSPDVWIKSLSWLH

GEMIN4

746

P57678
VHTWGENPIGTWTLR

PCSK1

556

P29120