Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentaxolemma

KCNC1 MAPT ROBO1

6.83e-0521803GO:0030673
GeneOntologyCellularComponentneuron projection membrane

KCNC1 MAPT ROBO1 DAGLA

2.77e-0482804GO:0032589
GeneOntologyCellularComponentactin cytoskeleton

LLGL1 GAS2L2 MYO9B ROR1 LPP FMN2 ABLIM2 STK38L MYO16

3.50e-04576809GO:0015629
GeneOntologyCellularComponentmain axon

KCNC1 MAPT ROBO1 DAGLA

3.79e-0489804GO:0044304
GeneOntologyCellularComponentmale pronucleus

RIF1 STPG4

3.99e-048802GO:0001940
GeneOntologyCellularComponentfemale pronucleus

RIF1 STPG4

6.38e-0410802GO:0001939
DomainBBOX

TRIM49 TRIM51 TRIM49C TRIM49B

1.79e-0469764SM00336
DomainButyrophylin

TRIM49 TRIM51 TRIM49C TRIM49B

1.89e-0470764IPR003879
Domain-

TRIM49 TRIM51 TRIM49C TRIM49B

2.00e-04717644.10.45.10
Domainzf-B_box

TRIM49 TRIM51 TRIM49C TRIM49B

2.11e-0472764PF00643
DomainZF_BBOX

TRIM49 TRIM51 TRIM49C TRIM49B

3.17e-0480764PS50119
DomainZnf_B-box

TRIM49 TRIM51 TRIM49C TRIM49B

3.32e-0481764IPR000315
DomainSPRY

TRIM49 TRIM51 TRIM49C TRIM49B

5.85e-0494764PF00622
DomainSPRY_dom

TRIM49 TRIM51 TRIM49C TRIM49B

5.85e-0494764IPR003877
DomainB30.2/SPRY

TRIM49 TRIM51 TRIM49C TRIM49B

6.09e-0495764IPR001870
DomainB302_SPRY

TRIM49 TRIM51 TRIM49C TRIM49B

6.09e-0495764PS50188
DomainDUF4599

SPATA31C2 SPATA31C1

1.05e-0312762PF15371
DomainDUF4599

SPATA31C2 SPATA31C1

1.05e-0312762IPR027970
DomainC1_1

RASGRP4 MYO9B VAV2

1.62e-0357763PF00130
DomainZF_DAG_PE_1

RASGRP4 MYO9B VAV2

2.26e-0364763PS00479
DomainZF_DAG_PE_2

RASGRP4 MYO9B VAV2

2.26e-0364763PS50081
DomainC1

RASGRP4 MYO9B VAV2

2.36e-0365763SM00109
DomainPE/DAG-bd

RASGRP4 MYO9B VAV2

2.46e-0366763IPR002219
DomainDEP_dom

FMN2 PREX2

3.91e-0323762IPR000591
DomainFrizzled_dom

FZD7 ROR1

4.26e-0324762IPR020067
DomainFZ

FZD7 ROR1

4.26e-0324762PS50038
DomainFz

FZD7 ROR1

4.26e-0324762PF01392
Pubmed

Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.

TRIM49 TRIM51 TRIM49C TRIM49B

3.65e-081581419703589
Pubmed

Identification of a genomic reservoir for new TRIM genes in primate genomes.

TRIM49 TRIM51 TRIM49C TRIM49B

1.03e-071981422144910
Pubmed

Lineage-specific biology revealed by a finished genome assembly of the mouse.

TRIM49 TRIM51 SEPTIN4 TRIM49C TRIM49B

1.92e-075581519468303
Pubmed

Deletion of Lrp4 increases the incidence of microphthalmia.

FZD7 PITX2 FGFR3 BMP15 SMAD9

6.05e-076981530352686
Pubmed

Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms.

ESRP2 ESRP1

5.36e-06281225143390
Pubmed

The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events.

ESRP2 ESRP1

5.36e-06281219829082
Pubmed

Dual Roles for Epithelial Splicing Regulatory Proteins 1 (ESRP1) and 2 (ESRP2) in Cancer Progression.

ESRP2 ESRP1

5.36e-06281227401076
Pubmed

Genome-wide determination of a broad ESRP-regulated posttranscriptional network by high-throughput sequencing.

ESRP2 ESRP1

5.36e-06281222354987
Pubmed

Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population.

LPP BCL6

5.36e-06281223749188
Pubmed

An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition.

ESRP2 ESRP1

5.36e-06281220711167
Pubmed

ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes.

UBTF POLR1G

5.36e-0628129426281
Pubmed

Downregulated ESRP1/2 promotes lung metastasis of bladder carcinoma through altering FGFR2 splicing and macrophage polarization.

ESRP2 ESRP1

5.36e-06281237090731
Pubmed

The global Protein-RNA interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function.

ESRP2 ESRP1

5.36e-06281236238894
Pubmed

Epithelial splicing regulatory protein 1 and 2 (ESRP1 and ESRP2) upregulation predicts poor prognosis in prostate cancer.

ESRP2 ESRP1

5.36e-06281233339518
Pubmed

Ablation of the epithelial-specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number.

ESRP2 ESRP1

5.36e-06281227404344
Pubmed

[Expressions of bcl-6, lpp and miR-28 genes in diffuse large B cell lymphoma cell lines].

LPP BCL6

1.60e-05381219236753
Pubmed

Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitability.

KCNC1 KCNB2

1.60e-05381221791288
Pubmed

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans.

ZC3H14 MAPT

1.60e-05381219273536
Pubmed

Krüppel-like factor 10 (KLF10) is transactivated by the transcription factor C/EBPβ and involved in early 3T3-L1 preadipocyte differentiation.

CEBPB KLF10

1.60e-05381230026232
Pubmed

RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor.

UBTF POLR1G

1.60e-05381216809778
Pubmed

The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma.

ESRP2 ESRP1

1.60e-05381226522722
Pubmed

Case Report: Identification of Potential Prognosis-Related TP53 Mutation and BCL6-LPP Fusion in Primary Pituitary Lymphoma by Next Generation Sequencing: Two Cases.

LPP BCL6

1.60e-05381234381423
Pubmed

Splicing factor ratio as an index of epithelial-mesenchymal transition and tumor aggressiveness in breast cancer.

ESRP2 ESRP1

1.60e-05381227911856
Pubmed

Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression.

MYO9B ROBO1

1.60e-05381226529257
Pubmed

Repression of an interleukin-4-responsive promoter requires cooperative BCL-6 function.

CEBPB BCL6

3.20e-05481215659391
Pubmed

ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.

ESRP2 ESRP1

3.20e-05481219285943
Pubmed

An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates.

ESRP2 ESRP1

3.20e-05481233234718
Pubmed

Rho GEFs and cancer: linking gene expression and metastatic dissemination.

PREX2 VAV2

3.20e-05481223033535
Pubmed

TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP.

ESRP2 ESRP1

3.20e-05481222037216
Pubmed

iRhom2 mutation leads to aberrant hair follicle differentiation in mice.

RHBDF2 TCF7L1 SMAD9

4.72e-053081325546423
Pubmed

Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus.

MAPT PITX2

5.33e-05581231474533
Pubmed

During embryogenesis, esrp1 expression is restricted to a subset of epithelial cells and is associated with splicing of a number of developmentally important genes.

ESRP2 ESRP1

5.33e-05581223233200
Pubmed

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

PREX2 VAV2

7.99e-05681225538043
Pubmed

Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity.

ESRP2 ESRP1

7.99e-05681230485810
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MON2 GGA2 LMTK2 TNRC6B

1.05e-0410481410470851
Pubmed

Genetic specification of left-right asymmetry in the diaphragm muscles and their motor innervation.

PITX2 ROBO1

1.12e-04781228639940
Pubmed

Regulation of motility of myogenic cells in filling limb muscle anlagen by Pitx2.

MAPT PITX2

1.12e-04781222558231
Pubmed

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses.

PREX2 VAV2

1.12e-04781221178006
Pubmed

CTCF regulates the local epigenetic state of ribosomal DNA repeats.

UBTF POLR1G

1.49e-04881221059229
Pubmed

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.

PREX2 VAV2

1.49e-04881224659802
Pubmed

Left-right function of dmrt2 genes is not conserved between zebrafish and mouse.

DMRT2 PITX2

1.49e-04881221203428
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

STOX2 GGA2 LPP TNRC6B MYO16

1.61e-0421881533378226
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

ESRP2 RIF1 ZCWPW1 CEBPB MYO9B PARG PITX2 INTS3 SMAD9

1.72e-0485781925609649
Pubmed

Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk.

FZD7 ESRP1 TCF7L1

1.83e-044781332253237
Pubmed

FOXF2 is required for cochlear development in humans and mice.

ROR1 FGFR3

1.91e-04981230561639
Pubmed

SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation.

KLF10 SMAD9

2.38e-041081216101586
Pubmed

The X-linked splicing regulator MBNL3 has been co-opted to restrict placental growth in eutherians.

ESRP2 ESRP1

2.38e-041081235476669
Pubmed

Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections.

MAPT DAGLA

2.38e-041081221050275
Pubmed

Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding.

MAPT DAGLA

2.38e-041081220962221
Pubmed

A census of human transcription factors: function, expression and evolution.

CEBPB DMRT2 KLF10 UBTF PITX2 BCL6 POU2F3 TCF7L1 SMAD9

2.63e-0490881919274049
Pubmed

Prostate cancer risk associated loci in African Americans.

LMTK2 TNRC6B

2.91e-041181219549807
Pubmed

Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling.

MAPT ROBO1

2.91e-041181225030704
Pubmed

TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function.

TCF7L1 CLDN1

3.48e-041281221938009
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

STOX2 ROR1 LPP TNRC6B KCNB2

3.82e-0426381534702444
Pubmed

The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2.

PITX2 FGFR3

4.11e-041381215329346
Pubmed

Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.

UBTF POLR1G

4.11e-041381215226435
Pubmed

BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment.

PITX2 SMAD9

4.11e-041381218550712
Pubmed

A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.

SEC24D TBCK PITX2

4.58e-046481320332099
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

FZD7 RIF1 KLF10 FGFR3 TCF7L1 BMP15

4.76e-0442481621731673
Pubmed

NFATc1 balances quiescence and proliferation of skin stem cells.

TCF7L1 SMAD9

4.79e-041481218243104
Pubmed

The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.

UBTF POLR1G

5.52e-041581236271492
Pubmed

A simple method for 3D analysis of immunolabeled axonal tracts in a transparent nervous system.

MAPT ROBO1

5.52e-041581225456121
Pubmed

ALK5-mediated transforming growth factor β signaling in neural crest cells controls craniofacial muscle development via tissue-tissue interactions.

PITX2 SMAD9

5.52e-041581224912677
Pubmed

Deletion of Yy1 in mouse lung epithelium unveils molecular mechanisms governing pleuropulmonary blastoma pathogenesis.

ESRP2 ESRP1

5.52e-041581233158935
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

RIF1 KLF10 UBTF LPP PITX2 ABLIM2 POU2F3 TCF7L1

5.92e-0480881820412781
Pubmed

Whole-transcriptome splicing profiling of E7.5 mouse primary germ layers reveals frequent alternative promoter usage during mouse early embryogenesis.

UBTF PITX2

6.29e-041681229592913
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RHBDF2 MAPT TBCK LPP TNRC6B PSMD1 ABLIM2 INTS3 STK38L DAGLA VAV2

6.60e-041489811128611215
Pubmed

Msx1 and Msx2 are required for endothelial-mesenchymal transformation of the atrioventricular cushions and patterning of the atrioventricular myocardium.

PITX2 SMAD9

7.12e-041781218667074
Pubmed

Fgf8 controls regional identity in the developing thalamus.

PITX2 FGFR3

7.12e-041781218653561
Pubmed

Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis.

PITX2 SMAD9

7.12e-041781218832393
Pubmed

A cluster of cholinergic premotor interneurons modulates mouse locomotor activity.

MAPT PITX2

7.12e-041781220005822
Pubmed

Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural crest cells condensation and outflow tract septation.

PITX2 SMAD9

8.00e-041881232105214
Pubmed

Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract.

PITX2 SMAD9

8.00e-041881217601530
Pubmed

Threshold-specific requirements for Bmp4 in mandibular development.

PITX2 SMAD9

8.00e-041881215936012
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

MON2 ZC3H14 LLGL1 LMTK2 PSMD1

8.38e-0431381538270169
Pubmed

Non-cell autonomous control of precerebellar neuron migration by Slit and Robo proteins.

MAPT ROBO1

8.93e-041981229343636
Pubmed

A microarray analysis of the XX Wnt4 mutant gonad targeted at the identification of genes involved in testis vascular differentiation.

PITX2 ROBO1

8.93e-041981216844427
Pubmed

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.

SEPTIN4 MAPT ROBO1

9.78e-048381319799774
Pubmed

Isl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor.

CLDN1 SMAD9

9.91e-042081228650075
Pubmed

Molecular evolution of Sry and Sox gene.

UBTF TCF7L1

9.91e-042081211404013
Pubmed

Persistent Wnt/β-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme.

PITX2 SMAD9

9.91e-042081230570432
Pubmed

Dpy19l1, a multi-transmembrane protein, regulates the radial migration of glutamatergic neurons in the developing cerebral cortex.

ZC3H14 SCMH1

9.91e-042081222028030
Pubmed

RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1.

PITX2 SMAD9

9.91e-042081232662771
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 FZD7 ESRP2 CEBPB KLF10 RHBDF2 MYO9B LMTK2 PRRT4

1.07e-03110581935748872
Pubmed

MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis.

FGFR3 SMAD9

1.09e-032181222632802
Pubmed

Nde1 is required for heterochromatin compaction and stability in neocortical neurons.

MAPT UBTF

1.09e-032181235601919
Pubmed

Dlx transcription factors promote migration through repression of axon and dendrite growth.

MAPT ROBO1

1.09e-032181217582329
Pubmed

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors.

PITX2 TCF7L1

1.20e-032281217919533
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

FZD7 PITX2 TCF7L1

1.24e-039081319515997
Pubmed

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.

ROBO1 FGFR3 BCL6

1.40e-039481323431145
Pubmed

Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones.

KLF10 SMAD9

1.43e-032481224583261
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

STOX2 GGA2 LMTK2 SENP6 DAGLA MINDY1

1.49e-0352981614621295
Pubmed

The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling.

PITX2 SMAD9

1.55e-032581233846290
Pubmed

Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease.

PITX2 FGFR3

1.55e-032581221518438
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

CEBPB KLF10 PITX2 BCL6 POU2F3 TCF7L1

1.72e-0354481628473536
Pubmed

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections.

FZD7 MAPT

1.81e-032781217804636
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

KCNC1 SEPTIN4 ROBO1 VAV2 MYO16

1.88e-0337681524154525
Pubmed

BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation.

FGFR3 SMAD9

1.95e-032881219224984
Pubmed

Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure.

ESRP2 ESRP1

1.95e-032881232005677
Pubmed

Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins.

FGFR3 SMAD9

1.95e-032881219762422
CytobandEnsembl 112 genes in cytogenetic band chr13q33

BIVM CCDC168 MYO16

1.30e-0455813chr13q33
Cytoband8q13.2

KCNB2 PREX2

1.67e-04118128q13.2
Cytoband13q33.1

BIVM CCDC168

2.01e-041281213q33.1
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM49 TRIM51 TRIM49C TRIM49B

1.99e-049555459
GeneFamilyReceptor Tyrosine Kinases|CD molecules

ROR1 LMTK2 FGFR3

2.43e-0440553321
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MAPT LMTK2 PREX2 MYO16

2.23e-03181554694
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

GGA2 ARSB AZIN2 ROBO1 KCNB2 SPATA31C1 TCF7L1

3.62e-08180807886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 SEPTIN4 ROR1 PRRT4 VAV2 MYO16

1.21e-06190806305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCellCOVID-19_Mild-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

ESRP1 CCDC168 CSMD2 TCF7L1 MYO16

2.99e-061248055ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 ARSB BCL6 POLR1G CLDN1

1.00e-051598057bb76324d2026d4bd348126cb169c8411f0d7145
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

CEBPB SEPTIN4 MAPT FGFR3 PREX2

1.17e-05164805519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO1 DAGLA TCF7L1 PREX2 PCDH17

1.88e-05181805fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ABLIM2 STK38L PREX2 PCDH17

1.98e-05183805dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROBO1 ABLIM2 STK38L PREX2 PCDH17

1.98e-051838054759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LLGL1 MAPT TTC31 PARG TBCK

2.09e-05185805daea170d827226dda6750bf1838ffd82f070c4d4
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

COL7A1 STOX2 FGFR3 TCF7L1 CLDN1

2.20e-051878058407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 BCL6 PREX2 MYO16 PCDH17

2.25e-05188805433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell367C-Epithelial_cells-Epithelial-H_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

COL7A1 ABCA12 ESRP1 FGFR3 CLDN1

2.25e-0518880561422c7919ca0ea02d6be4302f11b169a3ce35e5
ToppCell367C-Epithelial_cells-Epithelial-H_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

COL7A1 ABCA12 ESRP1 FGFR3 CLDN1

2.25e-0518880518698f0b22ccbc2b93759acc1c8dbdb30a6b5a16
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROBO1 BCL6 PREX2 MYO16 PCDH17

2.31e-05189805f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 ROR1 PRRT4 VAV2 MYO16

2.37e-051908053f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 ROR1 PRRT4 VAV2 MYO16

2.37e-05190805e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 SEPTIN4 ROR1 VAV2 MYO16

2.55e-05193805c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

FZD7 STOX2 ROR1 TCF7L1 PCDH17

2.96e-05199805358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SEPTIN4 ROR1 LPP VAV2 MYO16

3.03e-052008051276bfa911fddada4235e12e3081baa53164574b
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2--L2-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

KCNC1 SEPTIN4 ROR1 VAV2 MYO16

3.03e-05200805c65e6336725856c4b5f6aeba1cf86a23ec815d34
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

KCNC1 SEPTIN4 ROR1 VAV2 MYO16

3.03e-05200805117a25b3b9cdbc2e198381350a8362bee25e82e7
ToppCelldistal-2-Epithelial-Basal|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ESRP2 COL7A1 FGFR3 POLR1G CLDN1

3.03e-052008059beb128841c50241aa819261f21bf66f881ea125
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-WFDC2|Neuronal / cells hierarchy compared to all cells using T-Statistic

KCNC1 SEPTIN4 ROR1 VAV2 MYO16

3.03e-05200805d459e51507bf26865e6e7e04411379ec82a3edf8
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ESRP1 CSMD2 TCF7L1 MYO16

7.87e-0512680469b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DMRT2 KCNC1 CCDC168 MYO16

7.87e-0512680484dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ESRP1 CSMD2 TCF7L1 MYO16

7.87e-051268046cb89754010d64875e115da6c5805efac7a4a82d
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL7A1 DMRT2 ABCA12 CLDN1

1.28e-0414380428e936c298a45f88d14f0146caf3d5a22d483cd5
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FZD7 CEBPB ROR1 ROBO1

1.32e-041448041c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

GGA2 DMRT2 SENP6 CSMD2

1.50e-0414980468661c8facfb638560bb2e2c20d509941286dacb
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZCWPW1 SENP6 ABLIM2 CSMD2

1.71e-041548041c62290a2558fd6401b27de5a867d243b143b00a
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL7A1 DMRT2 GCGR CLDN1

1.88e-0415880498712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 BCL6 POLR1G CLDN1

1.93e-04159804807ee55fe0d3645fbfb98f641dd0a0555b847cf5
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCWPW1 ARSB KCNC1 FAM8A1

2.02e-04161804334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCWPW1 ARSB KCNC1 FAM8A1

2.02e-0416180481d44438e4be4e68a59247e62f02026301a8a0c5
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ROR1 KCNB2 POU2F3 SMAD9

2.07e-041628040ccdb224ee3c585a6d0caffde5608d9d3cc452f8
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD7 DMRT2 GCGR POU2F3

2.07e-041628043dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD7 DMRT2 GCGR POU2F3

2.07e-041628040a7138266054ea5954649c8b61ef93905d56b068
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ROR1 KCNB2 POU2F3 SMAD9

2.07e-041628040d35752a7249b3c62b8007ec8a775c37d16b8d31
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD7 DMRT2 GCGR POU2F3

2.07e-0416280425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ROR1 KCNB2 POU2F3 SMAD9

2.07e-041628049ccee8e7e78e16b0149a94867e12d86d3b04f9b9
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

CEBPB SEPTIN4 MAPT PREX2

2.12e-04163804f1ec2625b52664308968b01d8e0275e1e0751480
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MON2 FZD7 KLF10 MYO9B

2.17e-04164804b77995958c938e10a526118f75d78cee72e0b207
ToppCellBasal_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 ABCA12 FGFR3 CLDN1

2.38e-0416880448089fa2d4a0f31a72405717119b767a92571f01
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

KCNC1 PRRT4 VAV2 MYO16

2.43e-04169804c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZCWPW1 CEBPB APEX2 FGFR3

2.43e-041698047cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 POLR1G TCF7L1 CLDN1

2.49e-04170804776d4224a682b6c648041827efd69794f88906f0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BCL6 KCNB2 PREX2 CLDN1

2.49e-041708045d5f208682be21ed58320f5fc083a7898f8712da
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN4 ROR1 ROBO1 TCF7L1

2.60e-0417280408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ARSB DMRT2 ROBO1 PCDH17

2.60e-0417280404fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ARSB DMRT2 ROBO1 PCDH17

2.60e-04172804dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEPTIN4 ROR1 ROBO1 TCF7L1

2.60e-04172804553701349444eb366df3c11f54bb093434f153c6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRIM49 SEC24D TRIM49C CLDN1

2.72e-04174804912a9e892b29d945666fc37c986009c97c668ac8
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS2L2 MAPT CLDN1 PCDH17

2.72e-041748049d5dcd46cf346c381dea68ada6665f7fb68114a3
ToppCellfacs-Marrow-KLS-18m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAS2L2 MAPT CLDN1 PCDH17

2.72e-0417480453cec5c666c45278a71c21dd9c62a052a97e0fdf
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

COL7A1 ROBO1 FGFR3 SMAD9

2.72e-04174804fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR1 FGFR3 CLDN1 SMAD9

2.72e-04174804c58328c2f262506a4518f49f148e29874faf9171
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CEBPB SEPTIN4 PREX2 PCDH17

2.78e-04175804282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STOX2 ROR1 TNRC6B MYO16

2.90e-04177804b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SEPTIN4 PITX2 FGFR3 TCF7L1

2.96e-041788048f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL7A1 DMRT2 CLDN1 PCDH17

2.96e-04178804fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellwk_20-22-Epithelial-Proximal_epithelial-basal_proximal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

COL7A1 DMRT2 POU2F3 CLDN1

2.96e-041788049534c4f4e950bb1498c1737ca1713e7f37d0aff2
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

LLGL1 MAPT TTC31 PARG

3.03e-0417980410c7d371937d9d93c12c8d3465430ef9e0c2ec81
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

CEBPB SEPTIN4 FGFR3 PREX2

3.09e-04180804adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

COL7A1 FGFR3 TCF7L1 CLDN1

3.22e-04182804759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

COL7A1 FGFR3 TCF7L1 CLDN1

3.22e-04182804caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL7A1 AZIN2 FGFR3 PCDH17

3.22e-041828043fddadb2ff75013ec6eeb415872667a6bae1da2d
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESRP2 ABCA12 BCL6 CLDN1

3.29e-0418380426b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FMN2 ROBO1 ABLIM2 TCF7L1

3.29e-04183804848fc6dd129150897ee339343e83c645b6e779eb
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 ARSB BCL6 CLDN1

3.29e-04183804107cc756c45d6e92181659868d91188814dae66d
ToppCell(7)_Epithelial-H_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL7A1 ABCA12 FGFR3 CLDN1

3.36e-041848041f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TCF7L1 PREX2 PCDH17 SMAD9

3.36e-04184804688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 PRRT4 VAV2 MYO16

3.36e-041848042ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARSB ROR1 ROBO1 PREX2

3.36e-0418480467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STOX2 BCL6 CLDN1 SMAD9

3.36e-04184804da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FMN2 ROBO1 ABLIM2 CLDN1

3.43e-0418580434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 ROR1 VAV2 MYO16

3.43e-04185804e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCellBAL-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

SEPTIN4 BIVM SKIDA1 MINDY1

3.43e-04185804e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 ARSB BCL6 CLDN1

3.43e-04185804ed7b26bdebfd0df2b4f5020a855a052d94ae7219
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FMN2 ROBO1 ABLIM2 CLDN1

3.43e-041858048816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEPTIN4 MAPT FGFR3 PRRT4

3.50e-041868049d6cb36aa0aae69fe584dad31deafcfdcc9fd1db
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 PREX2 VAV2 MYO16

3.50e-0418680477592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROR1 ROBO1 PRRT4 VAV2

3.50e-0418680496f6603cc75fa1ffc2a2fdb94ec0ec09498e540a
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

STOX2 ROR1 LMTK2 MYO16

3.50e-0418680409d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STOX2 BCL6 TCF7L1 VAV2

3.50e-04186804f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

STOX2 SCMH1 KCNB2 CLDN1

3.50e-04186804b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 SEPTIN4 ROR1 MYO16

3.50e-041868046379609b7ace80683f5754b16aa77f11b43766ae
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STOX2 BCL6 TCF7L1 VAV2

3.57e-04187804c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DMRT2 MAPT ABLIM2 PREX2

3.57e-04187804a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

STOX2 PREX2 PCDH17 SMAD9

3.64e-04188804d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STOX2 BCL6 TCF7L1 VAV2

3.64e-04188804af740fa78542438fdff627ea1f74f4eee43316be
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FZD7 ZCWPW1 MAPT FMN2

3.64e-04188804c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

STOX2 PREX2 PCDH17 SMAD9

3.72e-04189804c121817ddad164e9cfe382c43d0cbc9215508d02
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

DMRT2 MAPT ABLIM2 PREX2

3.72e-04189804d7ed96add29f219183c802895fbff519b627f635
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

STOX2 ROR1 ESRP1 FGFR3

3.79e-041908048aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEPTIN4 MAPT FGFR3 PRRT4

3.79e-0419080452213cd2a6a20772d4f49ba9ac0407abafa528db
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

COL7A1 FGFR3 TCF7L1 CLDN1

3.79e-04190804ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNC1 SEPTIN4 ROR1 MYO16

3.79e-041908048c9c230a509afaeee50644153974a5642b01a2b8
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FZD7 COL7A1 POLR1G TCF7L1

3.79e-0419080439fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBTF PARG LPP SENP6

3.87e-0419180460c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

CEBPB SEPTIN4 MAPT PREX2

3.87e-041918043379d145d34f89150f7b06d1340022cfc6b4a6ce
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A_EA

ESRP2 GGA2 KLF10 UBTF ROBO1 FGFR3

4.07e-051847861064_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

FZD7 COL7A1 MAPT MYO9B TNRC6B BCL6

5.47e-051947867001_UP
DrugMethyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; PC3; HT_HG-U133A

MON2 ZC3H14 MAPT MYO9B UBTF VAV2

5.47e-051947864325_DN
DrugIsopropamide iodide [71-81-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A

FZD7 GGA2 ZCWPW1 MAPT MYO9B VAV2

5.62e-051957863461_DN
DrugBoldine [476-70-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

MON2 GGA2 LLGL1 LMTK2 SENP6 DAGLA

5.79e-051967864122_DN
DrugBrompheniramine maleate [980-71-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A

FZD7 GGA2 MYO9B LPP MINDY1 VAV2

5.79e-051967863271_DN
Drugbenserazide hydrochloride; Down 200; 10uM; SKMEL5; HG-U133A

GGA2 APEX2 UBTF TNRC6B BCL6 CLDN1

5.79e-05196786631_DN
Drugrottlerin; Up 200; 10uM; MCF7; HT_HG-U133A_EA

ZCWPW1 KCNC1 ABCA12 LPP STK38L VAV2

5.79e-05196786825_UP
DrugProchlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A

GGA2 ZCWPW1 ARSB FGFR3 STK38L DAGLA

5.95e-051977862641_DN
DrugLycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A

MON2 COL7A1 LLGL1 FGFR3 VAV2 PCDH17

6.12e-051987863891_UP
DrugCarteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

RIF1 LLGL1 MYO9B PITX2 VAV2 PCDH17

6.12e-051987864096_UP
DrugAllantoin [97-59-6]; Up 200; 25.2uM; MCF7; HT_HG-U133A

MON2 GGA2 LMTK2 DAGLA MINDY1 VAV2

6.29e-051997865471_UP
DrugMolindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A

SEC24D ZCWPW1 MAPT UBTF LPP SENP6

6.29e-051997867337_DN
DrugNitrofurantoin [67-20-9]; Up 200; 16.8uM; PC3; HT_HG-U133A

MON2 RIF1 MAPT PITX2 FGFR3 CLDN1

6.29e-051997863674_UP
DrugProxyphylline [603-00-9]; Up 200; 16.8uM; PC3; HT_HG-U133A

FZD7 ZCWPW1 KCNC1 LPP BCL6 DAGLA

6.29e-051997867290_UP
DrugMethimazole [60-56-0]; Down 200; 35uM; MCF7; HT_HG-U133A

COL7A1 MAPT LPP LMTK2 FGFR3 PCDH17

6.47e-052007864372_DN
Diseaseresponse to steroid, systemic lupus erythematosus, idiopathic osteonecrosis of the femoral head

TRIM49 MYO16

4.23e-054792EFO_0020976, EFO_1001930, MONDO_0007915
DiseaseHodgkins lymphoma

KRT39 LPP POLR1G TCF7L1

7.10e-0582794EFO_0000183
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

1.05e-046792EFO_0021525
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

1.96e-048792EFO_0010913
Diseasecortical surface area measurement

MON2 DMRT2 MAPT MYO9B UBTF ROR1 SKIDA1 TNRC6B ROBO1 FGFR3 TCF7L1 MYO16

2.32e-0413457912EFO_0010736
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

2.52e-049792EFO_0007645
DiseasePancreatic Ductal Adenocarcinoma

ABCA12 ABLIM2

3.83e-0411792C1335302
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

5.42e-0413792EFO_0005939, EFO_0007018
Diseasebone density

FZD7 MAPT UBTF FMN2 TCF7L1 SMAD9

6.16e-04388796EFO_0003923
Diseasecortical thickness

MON2 MAPT UBTF ROR1 FMN2 TNRC6B ROBO1 FGFR3 MYO16 PCDH17

7.61e-0411137910EFO_0004840
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1

8.29e-0416792EFO_0021490
Diseaselevel of Phosphatidylcholine (20:4_0:0) in blood serum

DAGLA TCF7L1

1.05e-0318792OBA_2045110
Diseasevisceral adipose tissue measurement

ZC3H14 LLGL1 ROBO1 KCNB2 PCDH17 STPG4

1.85e-03481796EFO_0004765
Diseasediet measurement

SCMH1 SKIDA1 TNRC6B ROBO1 POLR1G POU2F3 DAGLA MYO16 PCDH17

1.94e-031049799EFO_0008111
Diseasepseudotumor cerebri

KCNB2 FAM8A1

2.21e-0326792EFO_1001132
DiseaseAdenocarcinoma of large intestine

ROR1 TBCK FGFR3

2.21e-0396793C1319315
Diseasehearing impairment

ARSB PITX2 FGFR3

2.34e-0398793C1384666

Protein segments in the cluster

PeptideGeneStartEntry
FSAYPLTKCPPPTIL

CSMD2

2286

Q7Z408
KFPPTAKPTCYLAPR

ABCA12

46

Q86UK0
PRVRPFYAVKCNSSP

AZIN2

61

Q96A70
SIYKTPNPSRSPCLP

BIVM

81

Q86UB2
SKPPPSTYQQAPRHF

ABLIM2

406

Q6H8Q1
YFQPSPSCPQASPDI

APEX2

396

Q9UBZ4
RTQQPFPPTVPTKAY

C7orf31

176

Q8N865
CLSPPSYTFPAPAAV

ESRP1

551

Q6NXG1
SQYLSPSKQPRDPPF

PCDH17

1076

O14917
REKFPEFCSSPSPPV

INTS3

491

Q68E01
PTVATTPYGPFPCKA

LLGL1

276

Q15334
KRPCYPRATKCEPSP

KRT39

406

Q6A163
AGPCSSFPKIPYSPV

MYO16

1626

Q9Y6X6
SVPRPSCVPYKYVPI

BMP15

351

O95972
RNCSTPGPDIKLYPF

PARG

941

Q86W56
PPPTELVCNRTFDKY

GCGR

51

P47871
SYAREPRCPKSLPPS

RASGRP4

426

Q8TDF6
PQSPRTRQPEPDFYC

MINDY1

101

Q8N5J2
LECSSPYKPRPPQSS

LPP

131

Q93052
SKYFSPPPPARSTEQ

LMTK2

1446

Q8IWU2
PAPCPLNYVSQKSVP

GGA2

426

Q9UJY4
SSSPAPVEKPYFPIC

MON2

296

Q7Z3U7
CPVATPIKPPVYNSR

POU2F3

341

Q9UKI9
DSPYKPPVTRCNFTP

KIR3DX1

301

Q9H7L2
STPFSYPELPDSCQP

NBPF3

501

Q9H094
FPFSCPRQLKVPPYL

FZD7

206

O75084
PNPDCQEKPERPSAY

KCNB2

556

Q92953
PRPPQLGSPNYCKSV

KCNC1

461

P48547
AYSPSPVEPPSKDFC

DMRT2

286

Q9Y5R5
CPRKTTSYPTPRPYP

CLDN1

186

O95832
PPVCSIRPFKSSEQY

GAS2L2

16

Q8NHY3
PSPADAKAPPTACYA

CEBPB

236

P17676
PSARNAPYFPCDKAS

BCL6

286

P41182
PVYFPAQDPRCDPKA

ARSB

511

P15848
RPQYPTLKCFAYSPP

DAGLA

486

Q9Y4D2
YPCGKFCPRPFETPL

FAM47A

296

Q5JRC9
CLTPPYSPSDFEPSQ

KLF10

91

Q13118
KPRPPPVSAQSAFSY

C5orf49

16

A4QMS7
ASFTTQPRPEPCPVY

COL7A1

1236

Q02388
RKSASFPPPPFYLNC

CCDC168

4941

Q8NDH2
RPPGLDYSFDTCKPP

FGFR3

571

P22607
PAPSQRCFKPYPLIT

FMN2

401

Q9NZ56
AAFPAYCSPQPSPQS

FAM8A1

136

Q9UBU6
SKPPRVPCQDLTEPY

FAM166A

71

Q6J272
IYTIPNCSFSPPLRP

TRIM49

431

P0CI25
PPFCSETPQETYRKV

STK38L

321

Q9Y2H1
FSYLRCDNPPSPSPK

SPATA31C2

46

B4DYI2
QYFCAPAPLSPSARP

SEPTIN4

91

O43236
FRTLYAASCPLPPAP

FAM83E

281

Q2M2I3
KESIPCPTESVYPPL

RIF1

2281

Q5UIP0
YPEIVRSPCKPPLNY

SKIDA1

181

Q1XH10
RSPCKPPLNYETAPL

SKIDA1

186

Q1XH10
CKPSTFAYPAPLEVP

PSMD1

806

Q99460
RFSCPPNFTAKPPAS

POLR1G

11

O15446
PPTPPYVYRDTCNSS

PITX2

266

Q99697
PCKLPCLSPPTYTTF

ESRP2

576

Q9H6T0
FSYLRCDNPPSPSPR

SPATA31C1

46

P0DKV0
ATLDYCRKSKPPNPP

SEC24D

426

O94855
PAPVHCFKQSYTPPS

SCMH1

41

Q96GD3
TYPDSFQQPPCSALP

SMAD9

176

O15198
FCPLSSQRTESPYKP

TEPP

26

Q6URK8
AFPYCDETSSVPKPR

ROR1

231

Q01973
PPAQKSYSLLPCSPN

ZCWPW1

21

Q9H0M4
PPPIKYTCIQEPNES

CD96

561

P40200
SCLIPDPSLYKNPSP

SPEM3

1011

A0A1B0GUW6
VQYLPPEKPCDSPAS

TCF7L1

456

Q9HCS4
YCPPSLCQVPPTEKS

STOX2

226

Q9P2F5
PAPVPKYASRSCVFR

STPG4

146

Q8N801
IYTIPNCSFSPPLRP

TRIM51

431

Q9BSJ1
IYTIPNCSFSPPLRP

TRIM49C

431

P0CI26
SPCSDYTVDFRPPSP

PRRT4

711

C9JH25
CSTYQPTPPLSPASK

SENP6

211

Q9GZR1
VCPEPPSSPKYVSSV

MAPT

431

P10636
TPQSAPRLYKLCEPP

PREX2

1586

Q70Z35
PYCRPTFPTSNNPRD

ROBO1

1586

Q9Y6N7
PYFSAECPDPPKTDL

TBCK

731

Q8TEA7
PAPCQRTYVKYPTPC

XP32

71

Q5T750
RRTPYSTCPEPGDPF

TMEM221

216

A6NGB7
IYTIPNCSFSPPLRP

TRIM49B

431

A6NDI0
YFPSSSVKPCPVDGR

VAV2

641

P52735
RPTKPPPNSYSLYCA

UBTF

296

P17480
PQRPQTEEKPFHCPY

ZNF382

286

Q96SR6
ACPPSFLPKRKNPAY

RHBDF2

71

Q6PJF5
APPAPPSSSQLCRYF

ZC3H14

671

Q6PJT7
DEAPCSPFSPSPSYK

TNRC6B

1151

Q9UPQ9
KSFLYPPQESEPCPQ

TTC31

111

Q49AM3
AKRRYSDPPTYCLPP

MYO9B

2136

Q13459