Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionserine-type endopeptidase activity

HGF C1RL ST14 PRSS46P FAP KLK5 PLG

1.96e-041901257GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

HGF C1RL ST14 PRSS46P FAP KLK5 PLG

3.30e-042071257GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

HGF C1RL ST14 PRSS46P FAP KLK5 PLG

3.81e-042121257GO:0017171
GeneOntologyMolecularFunctionurea channel activity

AQP7P3 AQP7

3.84e-0451252GO:0015265
GeneOntologyMolecularFunctionhypotaurine monooxygenase activity

FMO3 FMO4

3.84e-0451252GO:0047822
GeneOntologyMolecularFunctionN,N-dimethylaniline monooxygenase activity

FMO3 FMO4

5.74e-0461252GO:0004499
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

NRG2 MST1R IGF1R KIT

7.38e-04651254GO:0004714
GeneOntologyMolecularFunctionglycerol channel activity

AQP7P3 AQP7

8.00e-0471252GO:0015254
GeneOntologyBiologicalProcesscell differentiation involved in embryonic placenta development

ST14 SPINT2 FZD5 HAND1 PLG

1.90e-06341265GO:0060706
GeneOntologyBiologicalProcesslabyrinthine layer development

ST14 SYDE1 SPINT2 FZD5 PLG

4.49e-05641265GO:0060711
GeneOntologyBiologicalProcessmyotube differentiation

NPHS1 AVPR1A NTN3 CNTNAP1 XBP1 CNTNAP2 CDON

6.75e-051641267GO:0014902
GeneOntologyBiologicalProcessbranching involved in labyrinthine layer morphogenesis

ST14 SPINT2 FZD5

7.71e-05141263GO:0060670
GeneOntologyBiologicalProcessembryonic placenta development

ST14 SYDE1 SPINT2 FZD5 HAND1 PLG

9.11e-051191266GO:0001892
GeneOntologyBiologicalProcessepithelial cell differentiation involved in embryonic placenta development

ST14 SPINT2

1.11e-0431262GO:0060671
GeneOntologyBiologicalProcessepithelial cell morphogenesis involved in placental branching

ST14 SPINT2

1.11e-0431262GO:0060672
GeneOntologyBiologicalProcessneuromuscular junction development, skeletal muscle fiber

CNTNAP1 CNTNAP2

1.11e-0431262GO:0098529
GeneOntologyCellularComponentextracellular matrix

NPHS1 ADAMTS19 ANG COL26A1 NTN3 LAMB3 SSPOP ITGB4 ENAM SRPX2 SBSPON NCAN LRRN2 PLG FBN3 CDON

1.92e-0665612516GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

NPHS1 ADAMTS19 ANG COL26A1 NTN3 LAMB3 SSPOP ITGB4 ENAM SRPX2 SBSPON NCAN LRRN2 PLG FBN3 CDON

2.00e-0665812516GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

NPHS1 ANG COL26A1 NTN3 LAMB3 SSPOP ITGB4 SRPX2 SBSPON NCAN PLG CDON

8.17e-0553012512GO:0062023
GeneOntologyCellularComponentcell surface

SIGLEC8 FOLR3 CUBN ITGB4 ST14 MST1R FAP SRPX2 CSF2RA FZD5 CNTNAP2 TRPV4 ADGRE5 PLG CLEC10A KIT ADGRA3 CDON

1.08e-04111112518GO:0009986
GeneOntologyCellularComponentbasal part of cell

ABCC1 NAIP AQP7P3 ITGB4 AQP7 ST14 FAP SLCO4C1 SLC22A3

4.55e-043781259GO:0045178
GeneOntologyCellularComponentbasement membrane

NPHS1 ANG NTN3 LAMB3 ITGB4

8.37e-041221255GO:0005604
GeneOntologyCellularComponentexternal side of plasma membrane

SIGLEC8 FOLR3 CUBN ST14 CSF2RA ADGRE5 PLG CLEC10A KIT ADGRA3

1.13e-0351912510GO:0009897
GeneOntologyCellularComponentbasal plasma membrane

ABCC1 NAIP AQP7P3 ITGB4 AQP7 ST14 SLCO4C1 SLC22A3

1.32e-033541258GO:0009925
DomainIg-like_fold

NPHS1 KALRN SIGLEC8 NRG2 CAMTA2 ITGB4 SIGLEC15 MST1R CILP2 IGF1R CSF2RA CNTN5 NCAN GPCPD1 LRRN2 IGSF1 KIT ADGRA3 CDON

2.04e-0770612419IPR013783
DomainGalactose-bd-like

CEP104 NTN3 CNTNAP1 LAMB3 SSPOP GLB1 SUN5 CNTNAP2

2.08e-07941248IPR008979
Domain-

NPHS1 KALRN SIGLEC8 NRG2 ITGB4 SIGLEC15 MST1R CILP2 IGF1R CSF2RA CNTN5 NCAN GPCPD1 LRRN2 IGSF1 KIT ADGRA3 CDON

3.89e-07663124182.60.40.10
DomainTSP_1

ADAMTS19 ISM1 SSPOP CILP2 SEMA5B SBSPON

3.78e-06631246PF00090
DomainIGc2

NPHS1 KALRN SIGLEC8 NRG2 CILP2 CNTN5 LRRN2 IGSF1 KIT CDON

3.83e-0623512410SM00408
DomainIg_sub2

NPHS1 KALRN SIGLEC8 NRG2 CILP2 CNTN5 LRRN2 IGSF1 KIT CDON

3.83e-0623512410IPR003598
DomainTSP1

ADAMTS19 ISM1 SSPOP CILP2 SEMA5B SBSPON

4.55e-06651246SM00209
DomainTSP1_rpt

ADAMTS19 ISM1 SSPOP CILP2 SEMA5B SBSPON

4.55e-06651246IPR000884
DomainTSP1

ADAMTS19 ISM1 SSPOP CILP2 SEMA5B SBSPON

4.55e-06651246PS50092
DomainIG

NPHS1 KALRN SIGLEC8 NRG2 SIGLEC15 CILP2 CNTN5 NCAN LRRN2 IGSF1 KIT ADGRA3 CDON

4.59e-0642112413SM00409
DomainIg_sub

NPHS1 KALRN SIGLEC8 NRG2 SIGLEC15 CILP2 CNTN5 NCAN LRRN2 IGSF1 KIT ADGRA3 CDON

4.59e-0642112413IPR003599
DomainIg_I-set

NPHS1 KALRN SIGLEC8 NRG2 CILP2 CNTN5 LRRN2 ADGRA3 CDON

5.01e-061901249IPR013098
DomainI-set

NPHS1 KALRN SIGLEC8 NRG2 CILP2 CNTN5 LRRN2 ADGRA3 CDON

5.01e-061901249PF07679
DomainEGF_1

NTN3 CNTNAP1 NRG2 LAMB3 CUBN SSPOP ITGB4 NCAN CNTNAP2 FBN3

7.87e-0625512410PS00022
DomainEGF_2

NTN3 CNTNAP1 NRG2 LAMB3 CUBN SSPOP ITGB4 NCAN CNTNAP2 FBN3

1.10e-0526512410PS01186
DomainIG_LIKE

NPHS1 KALRN SIGLEC8 NRG2 SIGLEC15 CILP2 CNTN5 NCAN LRRN2 IGSF1 KIT ADGRA3 CDON

2.36e-0549112413PS50835
DomainIg-like_dom

NPHS1 KALRN SIGLEC8 NRG2 SIGLEC15 CILP2 CNTN5 NCAN LRRN2 IGSF1 KIT ADGRA3 CDON

3.03e-0550312413IPR007110
DomainEGF-like_CS

NTN3 CNTNAP1 NRG2 LAMB3 CUBN ITGB4 NCAN CNTNAP2 FBN3

6.21e-052611249IPR013032
DomainPeptidase_S1A

HGF C1RL ST14 PRSS46P KLK5 PLG

1.07e-041131246IPR001314
DomainTRYPSIN_DOM

HGF C1RL ST14 PRSS46P KLK5 PLG

1.18e-041151246PS50240
DomainTryp_SPc

HGF C1RL ST14 PRSS46P KLK5 PLG

1.30e-041171246SM00020
DomainTrypsin_dom

HGF C1RL ST14 PRSS46P KLK5 PLG

1.56e-041211246IPR001254
DomainTrypsin

HGF C1RL ST14 PRSS46P KLK5 PLG

1.56e-041211246PF00089
DomainPeptidase_S1_PA

HGF C1RL ST14 PRSS46P KLK5 PLG

1.71e-041231246IPR009003
DomainEGF_3

CNTNAP1 NRG2 CUBN SSPOP NCAN CNTNAP2 ADGRE5 FBN3

1.75e-042351248PS50026
DomainEGF

CNTNAP1 NRG2 CUBN NCAN CNTNAP2 FBN3

1.95e-041261246PF00008
DomainFN3

NPHS1 KALRN ITGB4 IGF1R CSF2RA CNTN5 CDON

2.37e-041851247SM00060
Domainig

NPHS1 SIGLEC8 CNTN5 IGSF1 KIT ADGRA3 CDON

2.79e-041901247PF00047
DomainImmunoglobulin

NPHS1 SIGLEC8 CNTN5 IGSF1 KIT ADGRA3 CDON

2.79e-041901247IPR013151
DomainCUB

C1RL CUBN ST14 CSMD1

3.11e-04491244PF00431
DomainCUB

C1RL CUBN ST14 CSMD1

3.37e-04501244SM00042
DomainFA58C

CNTNAP1 SSPOP CNTNAP2

3.48e-04211243SM00231
DomainFA58C_3

CNTNAP1 SSPOP CNTNAP2

3.48e-04211243PS50022
DomainFA58C_1

CNTNAP1 SSPOP CNTNAP2

3.48e-04211243PS01285
DomainFA58C_2

CNTNAP1 SSPOP CNTNAP2

3.48e-04211243PS01286
DomainFN3

NPHS1 KALRN ITGB4 IGF1R CSF2RA CNTN5 CDON

3.69e-041991247PS50853
Domain-

C1RL CUBN ST14 CSMD1

3.92e-045212442.60.120.290
DomainCUB

C1RL CUBN ST14 CSMD1

4.21e-04531244PS01180
DomainFlavin_mOase

FMO3 FMO4

4.32e-0451242IPR000960
DomainDiMe-aniline_mOase

FMO3 FMO4

4.32e-0451242IPR012143
DomainFMO-like

FMO3 FMO4

4.32e-0451242PF00743
DomainPAN_AP

HGF PLG

4.32e-0451242SM00473
DomainFlavin_mOase-like

FMO3 FMO4

4.32e-0451242IPR020946
DomainFN3_dom

NPHS1 KALRN ITGB4 IGF1R CSF2RA CNTN5 CDON

4.95e-042091247IPR003961
DomainF5_F8_type_C

CNTNAP1 SSPOP CNTNAP2

5.22e-04241243PF00754
DomainFA58C

CNTNAP1 SSPOP CNTNAP2

5.22e-04241243IPR000421
DomainSushi_SCR_CCP_dom

C1RL SRPX2 NCAN CSMD1

5.57e-04571244IPR000436
DomainCUB_dom

C1RL CUBN ST14 CSMD1

5.57e-04571244IPR000859
DomainTRYPSIN_HIS

C1RL ST14 PRSS46P KLK5 PLG

6.20e-041031245IPR018114
DomainPEROXIDASE_1

MPO EPX

6.45e-0461242PS00435
DomainConA-like_dom

TRIM25 CNTNAP1 TRIM77 ITGB4 NBEAL2 CNTNAP2 NEURL4

6.54e-042191247IPR013320
DomainTRYPSIN_HIS

C1RL ST14 PRSS46P KLK5 PLG

7.37e-041071245PS00134
Domainfn3

NPHS1 KALRN ITGB4 IGF1R CNTN5 CDON

7.46e-041621246PF00041
DomainPan_app

HGF PLG

8.98e-0471242IPR003609
DomainPAN

HGF PLG

8.98e-0471242PS50948
DomainPAN_1

HGF PLG

8.98e-0471242PF00024
DomainEGF

CNTNAP1 NRG2 CUBN NCAN CNTNAP2 ADGRE5 FBN3

9.88e-042351247SM00181
DomainCarb-bd-like_fold

CILP2 GPCPD1

1.19e-0381242IPR013784
DomainEGF-like_dom

CNTNAP1 NRG2 CUBN NCAN CNTNAP2 ADGRE5 FBN3

1.38e-032491247IPR000742
Domain-

CNTNAP1 SSPOP GLB1 CNTNAP2

1.41e-037312442.60.120.260
DomainAn_peroxidase

MPO EPX

1.90e-03101242PF03098
DomainHaem_peroxidase_animal

MPO EPX

1.90e-03101242IPR019791
DomainHaem_peroxidase

MPO EPX

1.90e-03101242IPR010255
DomainPEROXIDASE_3

MPO EPX

1.90e-03101242PS50292
Domain-

MPO EPX

1.90e-031012421.10.640.10
DomainTRYPSIN_SER

C1RL ST14 KLK5 PLG

3.05e-03901244IPR033116
DomainPSI

ITGB4 MST1R SEMA5B

3.10e-03441243IPR016201
DomainPSI

ITGB4 MST1R SEMA5B

3.52e-03461243SM00423
DomainNeurexin-like

CNTNAP1 CNTNAP2

3.78e-03141242IPR003585
Domain4.1m

CNTNAP1 CNTNAP2

3.78e-03141242SM00294
DomainGrowth_fac_rcpt_

NTN3 CUBN IGF1R ADGRE5 FBN3

3.87e-031561245IPR009030
DomainEGF_Ca-bd_CS

CUBN NCAN ADGRE5 FBN3

3.99e-03971244IPR018097
DomainEGF_CA

CUBN NCAN ADGRE5 FBN3

4.29e-03991244PS01187
DomainASX_HYDROXYL

CUBN NCAN ADGRE5 FBN3

4.44e-031001244PS00010
DomainLaminin_N

NTN3 LAMB3

4.94e-03161242IPR008211
DomainLamNT

NTN3 LAMB3

4.94e-03161242SM00136
DomainLAMININ_NTER

NTN3 LAMB3

4.94e-03161242PS51117
DomainLaminin_N

NTN3 LAMB3

4.94e-03161242PF00055
DomainSushi

SRPX2 NCAN CSMD1

4.98e-03521243PF00084
DomainEGF-type_Asp/Asn_hydroxyl_site

CUBN NCAN ADGRE5 FBN3

5.46e-031061244IPR000152
DomainTRYPSIN_SER

C1RL ST14 KLK5 PLG

5.46e-031061244PS00135
DomainCCP

SRPX2 NCAN CSMD1

5.54e-03541243SM00032
DomainKringle_CS

HGF PLG

5.57e-03171242IPR018056
DomainEMI

COL26A1 SSPOP

5.57e-03171242PS51041
DomainKRINGLE_1

HGF PLG

5.57e-03171242PS00021
DomainKR

HGF PLG

5.57e-03171242SM00130
DomainKringle

HGF PLG

5.57e-03171242IPR000001
DomainKRINGLE_2

HGF PLG

5.57e-03171242PS50070
DomainKringle

HGF PLG

5.57e-03171242PF00051
DomainSUSHI

SRPX2 NCAN CSMD1

6.13e-03561243PS50923
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS19 FMO3 B3GALT6 CUBN SSPOP CSF2RA GLB1 SEMA5B SBSPON NCAN

1.20e-0525010110M27554
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS19 B3GALT6 SSPOP GLB1 SEMA5B SBSPON NCAN

7.41e-051431017M27275
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS19 SSPOP SEMA5B SBSPON

1.68e-04391014M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS19 SSPOP SEMA5B SBSPON

1.68e-04391014MM15165
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LARGE2 ABCC1 MAN2B1 DIPK1A CNTNAP1 B3GALT6 LAMB3 C1RL ITGB4 MST1R FAP ZC3H11A IGF1R GLB1 SLC22A3 ADGRE5 SDF2 ADGRA3 CDON

9.10e-0812011281935696571
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS19 ISM1 CUBN SSPOP CILP2 SEMA5B

3.61e-0775128620637190
Pubmed

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

HGF MST1R IGF1R KIT

3.35e-0628128418593464
Pubmed

Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.

CNTNAP1 CNTN5 CNTNAP2

1.05e-0512128324411736
Pubmed

Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.

MPO EPX

1.34e-052128226386352
Pubmed

Linkage of shambling with sex in linkage group VII of the mouse.

CNTNAP1 KIT

1.34e-05212825661165
Pubmed

Over-expression of AQP7 contributes to improve insulin resistance in adipocytes.

AQP7P3 AQP7

1.34e-052128222877989
Pubmed

Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.

MPO EPX

1.34e-052128228260049
Pubmed

Generation of a prostate from a single adult stem cell.

ISM1 KIT

1.34e-052128218946470
Pubmed

Aquaporin 7 is upregulated through the PI3K-Akt pathway and modulates decidualisation of endometrial stromal cells.

AQP7P3 AQP7

1.34e-052128237879294
Pubmed

Novel ENAM and LAMB3 mutations in Chinese families with hypoplastic amelogenesis imperfecta.

LAMB3 ENAM

1.34e-052128225769099
Pubmed

Replication analysis of genetic association of the NCAN-CILP2 region with plasma lipid levels and non-alcoholic fatty liver disease in Asian and Pacific ethnic groups.

CILP2 NCAN

1.34e-052128226758378
Pubmed

Prolonged Starvation Causes Up-Regulation of AQP1 in Adipose Tissue Capillaries of AQP7 Knock-Out Mice.

AQP7P3 AQP7

1.34e-052128227455244
Pubmed

Involvement of aquaporin-7 in the cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells.

AQP7P3 AQP7

1.34e-052128221968069
Pubmed

Activation of proHGF by St14 induces mouse embryonic stem cell differentiation.

HGF ST14

1.34e-052128227316827
Pubmed

Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.

AQP7P3 AQP7

1.34e-052128237432580
Pubmed

Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.

AQP7P3 AQP7

1.34e-052128217576812
Pubmed

Predictive values of FAP and HGF for tumor angiogenesis and metastasis in colorectal cancer.

HGF FAP

1.34e-052128228895412
Pubmed

Matriptase/epithin participates in mammary epithelial cell growth and morphogenesis through HGF activation.

HGF ST14

1.34e-052128219853659
Pubmed

Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells.

ST14 SPINT2

1.34e-052128225786220
Pubmed

Aquaporin 7 expression in postimplantation mouse uteri: a potential role for glycerol transport in uterine decidualization.

AQP7P3 AQP7

1.34e-052128221130427
Pubmed

The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.

AQP7P3 AQP7

1.34e-052128219297367
Pubmed

Expression of the mouse anti-müllerian hormone gene suggests a role in both male and female sexual differentiation.

AMH KIT

1.34e-05212821782869
Pubmed

Dynamic subcellular localization of aquaporin-7 in white adipocytes.

AQP7P3 AQP7

1.34e-052128225643985
Pubmed

Molecular characterization of human Aquaporin-7 gene and its chromosomal mapping.

AQP7P3 AQP7

1.34e-05212829714739
Pubmed

Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect.

MPO EPX

1.34e-05212827809065
Pubmed

Cryoprotectants up-regulate expression of mouse oocyte AQP7, which facilitates water diffusion during cryopreservation.

AQP7P3 AQP7

1.34e-052128223290745
Pubmed

Hepatocyte growth factor/c-Met signalling is important for the selection of transplanted hepatocytes.

HGF MST1R

1.34e-052128222287599
Pubmed

Serum hepatocyte growth factor activator inhibitor type I (HAI-I) and type 2 (HAI-2) in prostate cancer.

ST14 SPINT2

1.34e-052128216353247
Pubmed

Localization of the human estrogen-responsive finger protein (EEP) gene (ZNF147) within a YAC contig containing the myeloperoxidase (MPO) gene.

MPO TRIM25

1.34e-05212828530055
Pubmed

Roles of Fibroblast Activation Protein and Hepatocyte Growth Factor Expressions in Angiogenesis and Metastasis of Gastric Cancer.

HGF FAP

1.34e-052128229134462
Pubmed

Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer.

AQP7P3 AQP7

1.34e-052128232631905
Pubmed

Matriptase is required for the active form of hepatocyte growth factor induced Met, focal adhesion kinase and protein kinase B activation on neural stem/progenitor cell motility.

HGF ST14

1.34e-052128224685580
Pubmed

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.

MPO EPX

1.34e-052128227836774
Pubmed

Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel.

AQP7P3 AQP7

1.34e-052128211457862
Pubmed

Cardioprotective effect of St. Thomas' Hospital No. 2 solution against age-related changes in aquaporin-7-deficient mice.

AQP7P3 AQP7

1.34e-052128237691043
Pubmed

Recovery and maintenance of nephrin expression in cultured podocytes and identification of HGF as a repressor of nephrin.

NPHS1 HGF

1.34e-052128217244893
Pubmed

Aquaporin7 expression during perinatal development of mouse brain.

AQP7P3 AQP7

1.34e-052128217052846
Pubmed

GSK1904529A, a Potent IGF-IR Inhibitor, Reverses MRP1-Mediated Multidrug Resistance.

ABCC1 IGF1R

1.34e-052128228266043
Pubmed

Morphologic and functional analysis of sperm and testes in Aquaporin 7 knockout mice.

AQP7P3 AQP7

1.34e-052128217123523
Pubmed

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.

AQP7P3 AQP7

1.34e-052128211972053
Pubmed

Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.

AQP7P3 AQP7

1.34e-052128215591341
Pubmed

Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation.

AQP7P3 AQP7

1.34e-052128215746100
Pubmed

Aquaporin7 plays a crucial role in tolerance to hyperosmotic stress and in the survival of oocytes during cryopreservation.

AQP7P3 AQP7

1.34e-052128226634435
Pubmed

The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.

ST14 SPINT2

1.34e-052128229118397
Pubmed

The alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signaling.

CSF2RA KIT

1.34e-052128216760463
Pubmed

AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism.

AQP7P3 AQP7

1.34e-052128217077387
Pubmed

A new role for aquaporin 7 in insulin secretion.

AQP7P3 AQP7

1.34e-052128222415076
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

KALRN CNTN5 LRRN2 IGSF1 ADGRA3 CDON

3.16e-05162128625826454
Pubmed

TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts.

HGF LAMB3 KIT

3.82e-0518128323041440
Pubmed

Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9.

AQP7P3 AQP7

4.02e-053128212351427
Pubmed

Anti-obesity effect of carboxymethyl chitin by AMPK and aquaporin-7 pathways in 3T3-L1 adipocytes.

AQP7P3 AQP7

4.02e-053128220573496
Pubmed

Sex-specific association of rs16996148 SNP in the NCAN/CILP2/PBX4 and serum lipid levels in the Mulao and Han populations.

CILP2 NCAN

4.02e-053128222208664
Pubmed

The potential for repositioning antithyroid agents as antiasthma drugs.

MPO EPX

4.02e-053128227444178
Pubmed

Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice.

AQP7P3 AQP7

4.02e-053128215998844
Pubmed

Construction of a D2.B6-Fv-2r congenic mouse strain: nonlethality of the homozygous Fv-2' genotype.

MST1R GLB1

4.02e-05312826939921
Pubmed

Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α.

TRIM25 XBP1

4.02e-053128235871160
Pubmed

Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase.

AQP7P3 AQP7

4.02e-053128216009937
Pubmed

Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1B.

CNTNAP1 CNTNAP2

4.02e-053128220164332
Pubmed

Peroxidasin and eosinophil peroxidase, but not myeloperoxidase, contribute to renal fibrosis in the murine unilateral ureteral obstruction model.

MPO EPX

4.02e-053128230565999
Pubmed

The evolutionary conservation of the mammalian peroxidase genes.

MPO EPX

4.02e-053128212584448
Pubmed

Expression of aquaporin-7 and aquaporin-9 in tanycyte cells and choroid plexus during mouse estrus cycle.

AQP7P3 AQP7

4.02e-053128227746040
Pubmed

MDFI promotes the proliferation and tolerance to chemotherapy of colorectal cancer cells by binding ITGB4/LAMB3 to activate the AKT signaling pathway.

LAMB3 ITGB4

4.02e-053128238375821
Pubmed

The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans.

ST14 MST1R

4.02e-053128217456594
Pubmed

Aquaporin isoforms involved in physiological volume regulation of murine spermatozoa.

AQP7P3 AQP7

4.02e-053128218829704
Pubmed

Cross-talk between the proto-oncogenes Met and Ron.

HGF MST1R

4.02e-053128210871856
Pubmed

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

EPX ALOX15

4.02e-053128228566277
Pubmed

Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.

FMO3 FMO4

4.02e-053128211551524
Pubmed

TNIP1/ANXA6 and CSMD1 variants interacting with cigarette smoking, alcohol intake affect risk of psoriasis.

TNIP1 CSMD1

4.02e-053128223541940
Pubmed

Adipocyte lipolysis drives acute stress-induced insulin resistance.

AQP7P3 AQP7

4.02e-053128233097799
Pubmed

Association of Aquaporin 7 and 9 with Obesity and Fatty Liver in db/db Mice.

AQP7P3 AQP7

4.02e-053128238064372
Pubmed

Caspr and caspr2 are required for both radial and longitudinal organization of myelinated axons.

CNTNAP1 CNTNAP2

4.02e-053128225378149
Pubmed

Channel-dependent permeation of water and glycerol in mouse morulae.

AQP7P3 AQP7

4.02e-053128216339044
Pubmed

Matriptase drives early-onset intestinal failure in a mouse model of congenital tufting enteropathy.

ST14 SPINT2

4.02e-053128231628112
Pubmed

Potent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity.

ST14 SPINT2

4.02e-053128218713750
Pubmed

Thiocyanate modulates the catalytic activity of mammalian peroxidases.

MPO EPX

4.02e-053128215894800
Pubmed

Preservations of nephrin and synaptopodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice.

NPHS1 HGF

4.02e-053128221342325
Pubmed

Axonal domain disorganization in Caspr1 and Caspr2 mutant myelinated axons affects neuromuscular junction integrity, leading to muscle atrophy.

CNTNAP1 CNTNAP2

4.02e-053128228370195
Pubmed

The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model.

KALRN XBP1

4.02e-053128227646263
Pubmed

The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17.

MPO EPX

4.02e-053128210828600
Pubmed

Local injection of hepatocyte growth factor/scatter factor (HGF/SF) alters cyclic growth of murine hair follicles.

HGF KIT

4.02e-05312829540971
Pubmed

Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells.

SLC6A18 AMH SRPX2

4.52e-0519128325855264
Pubmed

Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.

ABCC1 ITGB4 IGF1R ADGRE5

5.16e-0555128438945485
Pubmed

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

NPHS1 GLIS3 CUBN

6.17e-0521128327591083
Pubmed

Mechanisms of Broad-Band UVB Irradiation‒Induced Itch in Mice.

TRPV4 KIT

8.02e-054128233812858
Pubmed

cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases.

MPO ALOX15

8.02e-05412828188678
Pubmed

Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin.

ST14 SPINT2

8.02e-054128229438412
Pubmed

Early-onset tufting enteropathy in HAI-2-deficient mice is independent of matriptase-mediated cleavage of EpCAM.

ST14 SPINT2

8.02e-054128237539662
Pubmed

Correlation of clinicopathological parameters with HGF, c-Met, EGFR, and IGF-1R expression in uveal melanoma.

HGF IGF1R

8.02e-054128220061986
Pubmed

Delineation of proteolytic and non-proteolytic functions of the membrane-anchored serine protease prostasin.

ST14 SPINT2

8.02e-054128227385010
Pubmed

Genetic variants, plasma lipoprotein(a) levels, and risk of cardiovascular morbidity and mortality among two prospective cohorts of type 2 diabetes.

SLC22A3 PLG

8.02e-054128221900290
Pubmed

Genetic variants in PLG, LPA, and SIGLEC 14 as well as smoking contribute to plasma plasminogen levels.

SLC22A3 PLG

8.02e-054128225208887
Pubmed

Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma.

CLEC10A KIT

8.02e-054128229038008
Pubmed

The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin.

ST14 SPINT2

8.02e-054128224962579
Pubmed

Keratinocyte expression of transgenic hepatocyte growth factor affects melanocyte development, leading to dermal melanocytosis.

HGF KIT

8.02e-054128210842060
Pubmed

Invasive breast cancer induces laminin-332 upregulation and integrin β4 neoexpression in myofibroblasts to confer an anoikis-resistant phenotype during tissue remodeling.

LAMB3 ITGB4

8.02e-054128222673183
Pubmed

Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS.

CNTNAP1 CNTNAP2

8.02e-054128231641127
Pubmed

Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation.

AQP7P3 AQP7

8.02e-054128211952783
Pubmed

Mapping of aminoacylase-1 and beta-galactosidase-A to homologous regions of human chromosome 3 and mouse chromosome 9 suggests location of additional genes.

MST1R GLB1

8.02e-05412826803586
Pubmed

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.

HGF ST14

8.02e-054128220015050
InteractionFBXO2 interactions

TRIM25 MAN2B1 FOLR3 FFAR1 CNTNAP1 LAMB3 C1RL ST14 SYNGAP1 CILP2 IGF1R KLK5 ASIC4 ADGRA3

2.45e-0741112414int:FBXO2
InteractionBTNL2 interactions

LARGE2 CNTNAP1 LAMB3 ST14 MST1R CILP2 LRRN2 ADGRA3

5.29e-061551248int:BTNL2
InteractionCNTNAP1 interactions

TRIM25 CNTNAP1 SYNGAP1 SPINT2 CNTNAP2 SDF2

1.62e-05871246int:CNTNAP1
CytobandEnsembl 112 genes in cytogenetic band chr19p13

AMH MAN2B1 SYDE1 HAUS8 MISP YIPF2 CILP2 NCAN ADGRE5 TIMM29 FBN3

1.56e-0579712811chr19p13
Cytoband19q13.1

NPHS1 FFAR1 SPINT2

5.00e-0455128319q13.1
GeneFamilyFibronectin type III domain containing

NPHS1 KALRN ITGB4 IGF1R CNTN5 CDON

7.65e-05160806555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

KALRN NRG2 CNTN5 LRRN2 ADGRA3 CDON

7.92e-05161806593
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

C1RL SRPX2 NCAN CSMD1

1.17e-04578041179
GeneFamilyImmunoglobulin like domain containing

NPHS1 CILP2 CNTN5 IGSF1 KIT CDON

2.14e-04193806594
GeneFamilyReceptor Tyrosine Kinases|CD molecules

MST1R IGF1R KIT

7.32e-0440803321
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ITGB4 MST1R IGF1R CSF2RA ADGRE5 CLEC10A KIT

1.79e-03394807471
CoexpressionNABA_MATRISOME

ADAMTS19 HGF AMH COL26A1 NTN3 ISM1 NRG2 LAMB3 SSPOP ST14 CILP2 SRPX2 SEMA5B SBSPON NCAN PLG CLEC10A FBN3

2.62e-06102612818M5889
CoexpressionONDER_CDH1_TARGETS_2_DN

DIPK1A LAMB3 ITGB4 ST14 MST1R MISP SPINT2 FZD5 NBEAL2 CNTNAP2 KLK5 ADGRA3

3.72e-0647312812M4306
CoexpressionNABA_MATRISOME

ADAMTS19 HGF AMH COL26A1 NTN3 ISM1 NRG2 LAMB3 SSPOP ST14 CILP2 SRPX2 SEMA5B SBSPON NCAN PLG CLEC10A

8.56e-06100812817MM17056
CoexpressionNABA_CORE_MATRISOME

COL26A1 NTN3 LAMB3 SSPOP CILP2 SRPX2 SBSPON NCAN FBN3

8.68e-062751289M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

NTN3 LAMB3 SSPOP CILP2 SRPX2 SBSPON FBN3

5.18e-051961287M3008
CoexpressionGSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_UP

THEMIS2 SLC6A18 AMH AGBL4 PIEZO2 TREH KIT

5.52e-051981287M9924
CoexpressionNABA_CORE_MATRISOME

COL26A1 NTN3 LAMB3 SSPOP CILP2 SRPX2 SBSPON NCAN

5.63e-052701288MM17057
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 ABAT CUBN AQP7 TREH DPF3 BHMT2 PLG CSMD1

3.14e-09183128985446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellHSPCs-Eo/Baso_prog.|World / Lineage and Cell class

MPO HGF MAN2B1 EPX IGF1R SPINT2 GLB1 SLC22A3 ALOX15

3.46e-091851289b40ea11f5e536438b400ca5fddfd4559789036bd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 ABAT CUBN AQP7 DPF3 BHMT2 TRPV4 PLG

6.32e-0818412889434731f651820b05335085582960f08fbf895de
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTS19 GLIS3 FAP SRPX2 PIEZO2 SH3D19 SBF2 CNTNAP2

9.89e-08195128870387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LARGE2 NRG2 LAMB3 ITGB4 TREH CSMD1 ALOX15

6.25e-0717012870cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LARGE2 NRG2 LAMB3 ITGB4 TREH CSMD1 ALOX15

6.25e-0717012872d880223d01bde4bf777bd6f50b7d2768489075f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 CUBN AQP7 DPF3 BHMT2 PLG CSMD1

8.20e-0717712872f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 ABAT CUBN DPF3 BHMT2 TRPV4 PLG

8.84e-071791287d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 CUBN DPF3 CNTN5 CNTNAP2 TRPV4 CSMD1

9.52e-071811287c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF EPX CILP2 IGF1R SLC22A3 PLG ALOX15

1.10e-0618512875527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABAT CUBN AQP7 DPF3 TRPV4 PLG CSMD1

1.14e-061861287a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AFAP1L1 PIEZO2 SH3D19 SBF2 GPCPD1 FAM124B KIT

1.46e-061931287e1d546165dcc2392f540162206852c4717d7306f
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3|TCGA-Stomach / Sample_Type by Project: Shred V9

HGF ISM1 FAP SRPX2 PIEZO2 LRRN2 FAM124B

1.51e-0619412872260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HGF KALRN GLIS3 SRPX2 PIEZO2 SH3D19 CNTNAP2

1.51e-061941287a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 ABAT CUBN SLCO4C1 TREH BHMT2 PLG

1.62e-0619612874ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B KALRN AGBL4 CNTN5 CNTNAP2 CSMD1 UNC79

1.73e-0619812878ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGF CNTNAP1 FAP PIEZO2 SEMA5B SLC22A3 CNTNAP2

1.79e-06199128783383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPF3 SLC22A3 CNTNAP2 ASIC4 KIT FBN3 ECE2

1.85e-0620012877e51715525fdb001b7042b2bfcb9de81ecb5e4ee
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPF3 SLC22A3 CNTNAP2 ADGRE5 ASIC4 KIT FBN3

1.85e-062001287501a3b93624df463458a35d3e6648d4ccc941724
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPF3 SLC22A3 CNTNAP2 ADGRE5 ASIC4 KIT FBN3

1.85e-062001287d1f36a8232411933b1494168ec912fd0e5246428
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPF3 SLC22A3 CNTNAP2 ASIC4 KIT FBN3 ECE2

1.85e-06200128775649534a98bc738fca62d071de0978dc61eb24f
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LARGE2 CAMTA2 CUBN SBSPON SLC22A3 NEURL4

2.98e-061381286611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SIGLEC8 ZNF689 CNTNAP1 SPINT2 ASCL4 CLEC10A

5.01e-0615112860b6b37734430918378ed94e40877f0c4ae9b25ec
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SIGLEC8 ZNF689 CNTNAP1 SPINT2 ASCL4 CLEC10A

5.01e-06151128630225a1a7800b0ae19e16ac164f561379eedb99d
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL26A1 FFAR1 SEMA5B CNTNAP2 ASIC4 KIT

5.82e-06155128699e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FFAR1 NRG2 NBEAL2 PLG KIT NEURL4

8.32e-06165128634fd00be2b28716c871ad9fb356de84a299a0c01
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM198 NRG2 LRRN2 CSMD1 KIT FBN3

9.54e-06169128605e12524d68d409fed386ffad233305683b4575b
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

ANO2 KALRN ITGB4 AFAP1L1 TIMM29 KIT

1.05e-051721286ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN DPF3 BHMT2 TRPV4 PLG UNC79

1.09e-0517312868888434641ea554a9b62c436e87920378eef29cd
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B ABAT DPF3 CNTNAP2 LRRN2 ASIC4

1.20e-051761286bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1B ABAT DPF3 CNTNAP2 LRRN2 ASIC4

1.20e-0517612863c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 CUBN DPF3 TRPV4 PLG CSMD1

1.20e-0517612861595dbeee336a81e581325d63208ec6262664ee9
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF ST14 IGF1R SLC22A3 PLG ALOX15

1.28e-051781286cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPF3 SLC22A3 ASIC4 KIT FBN3 ECE2

1.28e-0517812863c973aac16988e88f5677d3d695dd772ccfd6570
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRG2 XBP1 CUBN SSPOP SPINT2 GLB1

1.28e-051781286b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO4 LAMB3 PIEZO2 SPINT2 ALOX15 CDON

1.41e-051811286a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO4 LAMB3 PIEZO2 SPINT2 ALOX15 CDON

1.41e-051811286504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPF3 SLC22A3 ASIC4 KIT FBN3 ECE2

1.41e-051811286062f00736eed96e4f4327615d093558dd7d82b20
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO4 LAMB3 PIEZO2 SPINT2 ALOX15 CDON

1.41e-051811286a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 ABAT CUBN DPF3 PLG CSMD1

1.45e-0518212864a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 ABAT CUBN TREH DPF3 CSMD1

1.50e-051831286d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARGE2 FMO3 NRG2 LAMB3 ITGB4 TRPV4

1.50e-051831286ecac1cfaff7553a60305b34d6cede6973ffb5430
ToppCellfacs-Lung-EPCAM-3m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LARGE2 FMO3 NRG2 LAMB3 ITGB4 TRPV4

1.50e-051831286f6ebfd7f61e912f92bd07313cc213a171747ac03
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 KALRN SSPOP PIEZO2 CSMD1 UNC79

1.55e-0518412862cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 KALRN SSPOP PIEZO2 CSMD1 UNC79

1.55e-051841286ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 KALRN SSPOP PIEZO2 CSMD1 UNC79

1.55e-0518412862b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS19 TMEM198 NRG2 TREH CSMD1 KIT

1.59e-051851286686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPF3 SLC22A3 ADGRE5 ASIC4 KIT FBN3

1.59e-0518512860b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell10x5'-Liver-Myeloid_Dendritic-DC2|Liver / Manually curated celltypes from each tissue

NAIP EPX ST14 SPINT2 CSF2RA CLEC10A

1.64e-05186128692ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HGF KALRN GLIS3 PIEZO2 SH3D19 SBF2

1.69e-051871286a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 LAMB3 ITGB4 MISP SPINT2 TRPV4

1.69e-051871286fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCellwk_20-22-Endothelial-Lymph_endothelial-SCG3+_lymphatic_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ITGB4 AFAP1L1 SBSPON BHMT2 HAND1 LRRN2

1.69e-05187128655aad84b992412e487a32f4970620189a7380ba6
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO XBP1 YIPF2 SPINT2 GLB1 ALOX15

1.75e-0518812867e27e49ec1eb02fb74c86ec2ccb84751bc778b21
ToppCelldroplet-Marrow-nan-21m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO XBP1 YIPF2 SPINT2 GLB1 ALOX15

1.75e-0518812864b14c3ad80507245564d5be96d33fd9361f67dd0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABAT CUBN DPF3 BHMT2 TRPV4 PLG

1.75e-051881286f3edcefeef2ce19086032d98b243c02a6d542b38
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TMEM198 FAP CILP2 SRPX2 HAND1 TRPV4

1.75e-0518812865a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABAT CUBN DPF3 BHMT2 TRPV4 PLG

1.75e-0518812860792432cd4c564dea1102241ea9884f7ced7658c
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LARGE2 FMO3 LAMB3 ITGB4 MISP TRPV4

1.85e-05190128647e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LARGE2 FMO3 LAMB3 ITGB4 MISP TRPV4

1.85e-051901286261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF FMO3 KALRN GLIS3 SRPX2 ADGRE5

1.85e-0519012861121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HGF FMO3 KALRN GLIS3 SRPX2 ADGRE5

1.85e-051901286048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHF19 GLIS3 EPX IGSF1 ALOX15

1.89e-051131285fed408864201218295bac0cc6647953fda8d688e
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHF19 GLIS3 EPX IGSF1 ALOX15

1.89e-051131285c0b8d7a2e3722029e850051bdff77f31f34a8cca
ToppCellCerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)|Cerebellum / BrainAtlas - Mouse McCarroll V32

PHF19 GLIS3 EPX IGSF1 ALOX15

1.89e-0511312857e24c0f6a80e10a2a41325d48a87628bd330a1e2
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANG LAMB3 ST14 MISP SPINT2 IGSF1

1.97e-0519212869f7e0d610741288d0779bd7c02852c791431e4ea
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPF3 SLC22A3 ASIC4 KIT FBN3 ECE2

1.97e-0519212866a252e298f8a454623fa9c1c893a7a45a886d694
ToppCell11.5-Airway-Epithelial-Bud_tip_adjacent|Airway / Age, Tissue, Lineage and Cell class

LARGE2 LAMB3 ST14 MISP SPINT2 SLC22A3

1.97e-051921286fbb34a959b9bd9cb72a5195a07f4653a957e4ca8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A18 ABAT CUBN TREH PLG CSMD1

1.97e-0519212863e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

GLIS3 CUBN AGBL4 IGF1R SH3D19 SBF2

1.97e-051921286e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GLIS3 FAP SRPX2 PIEZO2 SH3D19 CNTNAP2

2.09e-05194128699577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KALRN GLIS3 SRPX2 PIEZO2 SH3D19 CNTNAP2

2.09e-0519412868c37bedb23285735ff3828db3889897fada8c95d
ToppCell18-Airway-Epithelial-Bud_tip_adjacent|Airway / Age, Tissue, Lineage and Cell class

FOLR3 LAMB3 MISP FZD5 SLC22A3 FBN3

2.09e-051941286b45f1e80074a19245bc5dc4b3a583419a1904404
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

MAN2B1 COL26A1 ST14 SPINT2 CSF2RA CLEC10A

2.09e-051941286768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B KALRN AGBL4 CNTNAP2 CSMD1 UNC79

2.21e-051961286676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PHF19 NRG2 AQP7 ST14 AFAP1L1 CSF2RA

2.21e-05196128684c7f2153b5a9c4da7ae48fdf816a163c33d9a5e
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KALRN GLIS3 SRPX2 PIEZO2 SBF2 CNTNAP2

2.21e-0519612861450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell11.5-Distal-Epithelial-Bud_tip_adjacent|Distal / Age, Tissue, Lineage and Cell class

LAMB3 ST14 MISP SPINT2 FZD5 SLC22A3

2.21e-051961286a6a242868df0d2ff30825624a8d7c0367527594d
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS2 MAN2B1 NAIP CSF2RA ASCL4 CLEC10A

2.27e-05197128610190b877bf46ba2163d203df9dd3b498c66e52f
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANG LAMB3 CUBN ST14 MISP SPINT2

2.27e-051971286a6a27e5809ee2c9b56c7e06c35e4f140f9fa13ad
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGF COL26A1 FAP PIEZO2 SEMA5B SLC22A3

2.27e-0519712866668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HGF COL26A1 FAP PIEZO2 SEMA5B SLC22A3

2.27e-0519712867c275a2ac24a9a4f83fceda93a067e754837102f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GLIS3 SRPX2 PIEZO2 SH3D19 SBF2 CNTNAP2

2.27e-0519712860034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANG LAMB3 ST14 MISP SPINT2 IGSF1

2.27e-051971286755a53d4206354583bc5b76b63a0b1c9892b7382
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B KALRN AGBL4 CNTNAP2 CSMD1 UNC79

2.34e-051981286c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell15-Distal-Epithelial-Bud_tip_adjacent|Distal / Age, Tissue, Lineage and Cell class

LAMB3 MISP SPINT2 FZD5 SLC22A3 FBN3

2.34e-051981286f4d9d5995a42f71bf412f0ad299fc963bad3a898
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B KALRN AGBL4 CNTNAP2 CSMD1 UNC79

2.34e-0519812866d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B KALRN AGBL4 CNTNAP2 CSMD1 UNC79

2.34e-0519812864ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B KALRN AGBL4 CNTNAP2 CSMD1 UNC79

2.34e-0519812860ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANG GLIS3 LAMB3 ST14 MISP SPINT2

2.34e-051981286edf3e1c2be9df5690492b9c8fc25e7e48ed5c92c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

XBP1 ST14 MISP SRPX2 SPINT2 ALOX15

2.41e-05199128673704e8d774b3d08a311f69137972b07015c38f6
ToppCellcontrol-cDC|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ST14 SPINT2 CSF2RA GLB1 CLEC10A KIT

2.41e-05199128631825ba336603fe940dea6022e18ec25af110f4c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB3 CUBN ST14 MISP SPINT2 TREH

2.41e-051991286a10768e1cddd2d38291c30d24820a94040a72211
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB3 CUBN ST14 MISP SPINT2 TREH

2.41e-051991286f26c20f5d7470e90eaa79613d0b87bd4865585a8
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1B KALRN AGBL4 CNTNAP2 CSMD1 UNC79

2.47e-05200128648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS19 NRG2 XBP1 SLC22A3 GPCPD1 ALDH18A1

2.47e-0520012867c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPF3 SLC22A3 CNTNAP2 ASIC4 KIT FBN3

2.47e-052001286140aff451cd58e1d544ee668e49e37e577f6f068
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPF3 SLC22A3 CNTNAP2 ASIC4 KIT FBN3

2.47e-05200128685bfa7f4dd07a4d4a88330e88f5886fd1ecfdeeb
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma,_Immature_Teratoma,_Mature_Teratoma,_Yolk_Sac_Tumor|TCGA-Testes / Sample_Type by Project: Shred V9

HGF LAMB3 SBSPON ASCL4 HAND1

4.93e-051381285f7c40156c34d2d910bbda5ba07540ad0f6f22981
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Chromophobe-9|TCGA-Kidney / Sample_Type by Project: Shred V9

NRG2 BAALC-AS2 ASCL4 KIT FBN3

5.11e-051391285a93b861906d7f01ff715084f99152ec83529f8b3
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Chromophobe|TCGA-Kidney / Sample_Type by Project: Shred V9

NRG2 BAALC-AS2 ASCL4 KIT FBN3

5.28e-051401285bc5bed94c33129391ca35791febb55cc4cdff989
Diseasegranulosa cell tumor (is_marker_for)

AMH ST14 KIT

1.11e-05111223DOID:2999 (is_marker_for)
Diseaselymphocyte count

DAGLB THEMIS2 ABCC1 PHF19 KALRN ZNF689 GLIS3 XBP1 TNIP1 ZNF217 EPX MST1R FAP CILP2 CNTN5 ALDH18A1 ADGRE5 NEURL4

3.30e-05146412218EFO_0004587
Diseasegastroschisis (biomarker_via_orthology)

IGF1R KIT

5.07e-0531222DOID:11044 (biomarker_via_orthology)
Diseasecysteinylglycine measurement

ABCC1 FMO4

5.07e-0531222EFO_0800133
DiseaseHerlitz Disease

LAMB3 ITGB4

1.01e-0441222C0079683
DiseaseEpidermolysis Bullosa Progressiva

LAMB3 ITGB4

1.01e-0441222C0079297
Diseasepsychosis predisposition measurement

ABCC1 TRMT11 CSMD1

1.67e-04261223EFO_0008337
DiseaseAdult junctional epidermolysis bullosa (disorder)

LAMB3 ITGB4

1.68e-0451222C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

LAMB3 ITGB4

1.68e-0451222C2608084
DiseaseColoboma of optic disc

SPINT2 FZD5

1.68e-0451222C0155299
Diseasehearing threshold measurement, pure tone hearing measurement

TRPV4 ADGRA3

1.68e-0451222EFO_0007617, EFO_0007618
DiseaseAmelogenesis imperfecta type 1

LAMB3 ENAM

1.68e-0451222cv:C0399367
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

LAMB3 ITGB4

1.68e-0451222DOID:0060738 (implicated_via_orthology)
DiseaseJunctional Epidermolysis Bullosa

LAMB3 ITGB4

2.52e-0461222C0079301
Diseaseangiostatin measurement

SLC22A3 PLG

2.52e-0461222EFO_0008024
DiseaseLung diseases

MPO IGF1R ADGRE5 KIT

3.13e-04781224C0024115
Diseasejunctional epidermolysis bullosa (is_implicated_in)

LAMB3 ITGB4

3.51e-0471222DOID:3209 (is_implicated_in)
DiseaseAmelogenesis imperfecta local hypoplastic form

LAMB3 ENAM

3.51e-0471222C0399367
Diseaselipoprotein A measurement, apolipoprotein A 1 measurement

SLC22A3 PLG

3.51e-0471222EFO_0004614, EFO_0006925
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP1 CNTNAP2

4.67e-0481222DOID:0060308 (implicated_via_orthology)
DiseaseDevelopmental delay (disorder)

ABAT SZT2 IGF1R

4.84e-04371223C0424605
Diseasewaist-hip ratio

THEMIS2 XBP1 TRMT11 ZC3H11B AGBL4 HAUS8 IGF1R SLC22A3 CNTN5 SBF2 GPCPD1 ASCL4 FAM124B CDON

5.55e-04122612214EFO_0004343
Diseaselifestyle measurement, systolic blood pressure

KALRN CHFR

5.99e-0491222EFO_0006335, EFO_0010724
Diseasealbuminuria

CUBN AQP7 SBF2 CSMD1

6.37e-04941224EFO_0004285
DiseaseCharcot-Marie-Tooth disease

CNTNAP1 SBF2 TRPV4

7.04e-04421223cv:C0007959
Diseaseglucagon-like peptide-1 measurement

ENAM CSMD1

7.47e-04101222EFO_0008465
Diseaseliver fat measurement

ZNF217 NCAN CNTNAP2

7.54e-04431223EFO_0010821
Diseasedimethylglycine measurement

DPF3 CNTN5 BHMT2

9.19e-04461223EFO_0010476
Diseasesphingomyelin measurement

ISM1 CAMTA2 NCAN PLG FBN3 ALOX15

1.08e-032781226EFO_0010118
DiseaseAmelogenesis Imperfecta

ITGB4 ENAM

1.09e-03121222C0002452
Diseasemonocyte count

DAGLB THEMIS2 MPO MARS2 KALRN SZT2 TMEM121B GLIS3 CILP2 SLC22A3 CNTN5 ADGRE5 PLG KIT

1.13e-03132012214EFO_0005091
Diseaseeosinophil count

THEMIS2 ADAMTS19 DIPK1A TMEM121B TNIP1 EPX FBXO46 FAP CILP2 CSF2RA GLB1 SBF2 TIMM29 KIT ALOX15

1.25e-03148812215EFO_0004842
DiseaseCongenital Hypothyroidism

GLIS3 IGSF1

1.28e-03131222C0010308
DiseasePeripheral Nervous System Diseases

CACNA1B ABCC1 IGF1R

1.47e-03541223C4721453
DiseaseMalignant neoplasm of breast

THEMIS2 ADAMTS19 ABCC1 KALRN XBP1 TRMT11 TNIP1 CUBN ZC3H11A IGF1R SEMA5B KIT

1.68e-03107412212C0006142
Diseasemyeloid white cell count

THEMIS2 MPO PHF19 NAIP GLIS3 FAP SH3D19 CNTN5 SBF2 ADGRE5 KIT

1.78e-0393712211EFO_0007988
DiseaseSpondyloepiphyseal Dysplasia

GLB1 TRPV4

1.96e-03161222C0038015
DiseaseSpondyloepiphyseal Dysplasia Tarda, X-Linked

GLB1 TRPV4

1.96e-03161222C3541456
DiseaseSchwartz-Jampel Syndrome, Type 1

GLB1 TRPV4

1.96e-03161222C4551479
DiseaseSchwartz-Jampel Syndrome

GLB1 TRPV4

1.96e-03161222C0036391
DiseaseMelnick-Needles Syndrome

GLB1 TRPV4

1.96e-03161222C0025237
Diseaseplatelet crit

THEMIS2 KALRN DIPK1A CUBN EPX IGF1R SPINT2 CNTN5 NCAN LRRN2 KIT

2.02e-0395212211EFO_0007985
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

CACNA1B COL26A1 SIGLEC15 FAP CSMD1

2.08e-032161225EFO_0007925, EFO_0007927
Diseasepolyunsaturated fatty acid measurement

SLC22A3 NCAN PLG CLEC10A

2.18e-031311224EFO_0010733
DiseaseVan Buchem disease

GLB1 TRPV4

2.21e-03171222C0432272
DiseaseAmelogenesis imperfecta

LAMB3 ENAM

2.21e-03171222cv:C0002452
DiseaseGlobal developmental delay

CACNA1B ABAT SZT2 IGF1R

2.30e-031331224C0557874
DiseaseOsteochondrodysplasias

GLB1 TRPV4

2.77e-03191222C0029422
Diseaserenovascular hypertension (biomarker_via_orthology)

MPO AVPR1A

2.77e-03191222DOID:1591 (biomarker_via_orthology)
Diseasekidney failure (biomarker_via_orthology)

NPHS1 SLCO4C1

2.77e-03191222DOID:1074 (biomarker_via_orthology)
DiseaseDyschondroplasias

GLB1 TRPV4

2.77e-03191222C0013366
Diseasecreatinine measurement

NPHS1 GLIS3 CUBN ST14 FAP CILP2 IGF1R DPF3 SLC22A3 TRPV4 ASIC4

2.84e-0399512211EFO_0004518
Diseaseschizophrenia (implicated_via_orthology)

AVPR1A SYNGAP1 CSMD1

2.84e-03681223DOID:5419 (implicated_via_orthology)
Diseaseurinary microalbumin measurement

CUBN CNTNAP2

3.07e-03201222EFO_0010967
DiseaseMultiple Epiphyseal Dysplasia

GLB1 TRPV4

3.07e-03201222C0026760
Diseasemyeloperoxidase (MPO)-DNA complex measurement

MPO EPX

3.71e-03221222EFO_0011039
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

CILP2 SLC22A3 NCAN PLG

3.80e-031531224EFO_0004611, EFO_0020946
DiseaseNon-Small Cell Lung Carcinoma

TRMT11 ITGB4 CHFR KIT

4.07e-031561224C0007131

Protein segments in the cluster

PeptideGeneStartEntry
FRNWPFYVQGISPCV

NAIP

166

Q13075
GSGWQPPRPCEAYRA

C22orf39

41

Q6P5X5
VYDWSAPPSQCCQRR

B3GALT6

311

Q96L58
FFLRPLRCYGDRNSW

CNTNAP1

771

P78357
RRWNYPSPLCIATCG

CSMD1

1961

Q96PZ7
PGSYPNNLDCTWRIS

CSMD1

1991

Q96PZ7
RRAPFLIYGSDGPWC

BAALC-AS2

81

P0C853
PLDCYNIHWPIRRGQ

ACTR8

176

Q9H981
YPGNPQDERKAWRRC

ADGRA3

386

Q8IWK6
VGSYQCRCRPGWQPI

ADGRE5

181

P48960
QYEIRNCWPPVLSGG

CCNE2

51

O96020
PTFHRRCYWLLQNPD

CAMTA2

126

O94983
YNQDRSFCRPVLPWG

C14orf28

16

Q4W4Y0
QFCRFKDYREPPWAP

ANO2

876

Q9NQ90
AYCCPGWRTFPGRSQ

FBN3

66

Q75N90
TECREYWPGPNFGIT

CACNA1B

281

Q00975
LNCEVRGNPVPSYRW

CNTN5

121

O94779
PGCSLEDFVRWYSPR

RAB3GAP1

691

Q15042
PAGLPGFRDWQCQAY

ADAMTS19

686

Q8TE59
CPRYDPRFVGFGWNK

LARGE2

626

Q8N3Y3
CPQANRGVVRWEYFR

MISP

491

Q8IVT2
PEAFNWTFRGYRLSP

NPHS1

676

O60500
CSPYQFRLVGPGQWP

FMO3

466

P31513
CGEDWFRPKLNYRVP

MAD2L1BP

221

Q15013
PTIDWYFCPGTEQRC

KIT

436

P10721
GPRSQRRTVWPCYDD

SBF2

1616

Q86WG5
ASRFYIPEGCIQRWA

RPS6KC1

896

Q96S38
LAPGQLYTYPARCWR

DPF3

66

Q92784
CQRPWKLVEASYPGQ

ENTPD8

381

Q5MY95
RANRLGPLPFWLLYC

GPR137

86

Q96N19
PQCACQIRPWYTPRS

LRRN2

31

O75325
NCALGRVPWRKFPVY

AQP7P3

101

A6NL99
RPNAPYRIFNTWLGD

ABAT

371

P80404
FNLGRYWPARGPQLT

GLB1

586

P16278
FYQFSCGGWIRRNPL

ECE2

166

P0DPD6
VPACPPNTYRFEGWR

IGF1R

261

P08069
LWCPRPFGTYSQNQP

FBXO46

11

Q6PJ61
YNAWRRFCGLSQPRN

EPX

571

P11678
LPGYNAWRRFCGLPQ

MPO

596

P05164
KCEAAAGNPQPSYRW

NRG2

256

O14511
RLAWEVFFGPCTPYQ

FMO4

456

P31512
CPYQFRVSASNPWGI

KALRN

2636

O60229
PGAGDEVRFPCYRWV

ALOX15

86

P16050
LYECSPNLGPWIRQV

FOLR3

106

P41439
PASRCHQERPYFQSW

HAND1

31

O96004
QGLVSWGDYPCARPN

KLK5

256

Q9Y337
VCGWPQSDRNPRYGN

AMH

491

P03971
NCALGRVPWRKFPVY

AQP7

101

O14520
SPWPPCQYRATAGFR

ANG

111

P03950
LTYLPQPWGNCRAES

ASIC4

286

Q96FT7
DDNYCRNPDGQPRPW

HGF

256

P14210
RNPDGQPRPWCYTLD

HGF

261

P14210
APPSRWYFNQDSACR

HAUS8

341

Q9BT25
VSWQEPRCERPLQGY

ITGB4

1546

P16144
YRCGFQPFNQHLLPW

ALDH18A1

6

P54886
GRCKPFYCDRPWQRA

NTN3

286

O00634
FFPNVYPGERTCRWT

CUBN

831

O60494
CSPLMRQYGFAWPER

FZD5

116

Q13467
PVAVTSRPDCYWGRN

CHFR

626

Q96EP1
VSGWRSPRFCQFPQE

CEP104

31

O60308
HSPWQCYPTQDTRGR

FAM124B

91

Q9H5Z6
PLEQQRPSGYRADFW

IGSF1

1106

Q8N6C5
SQPECGYGLQPDRWT

GPCPD1

201

Q9NPB8
EYWENLLPASGRPFC

BHMT2

341

Q9H2M3
PLGYQAFRRPCYSWG

FFAR1

111

O14842
WPLYIYRNPLTGLCR

DAGLB

291

Q8NCG7
PQVRCYAFSPPRGLW

DAGLB

461

Q8NCG7
CFWAGCPRRYKPFNA

GLIS3

381

Q8NEA6
CNASGLPVPVIRWYD

CDON

426

Q4KMG0
YSRLPVAPREACNAW

C1RL

391

Q9NZP8
RPDTCNPRFRVWFNF

AGBL4

71

Q5VU57
VLPNGYNPPRNLCWD

MAN2B1

256

O00754
RSGCARGWQYLPVPL

ASCL4

51

Q6XD76
ERCAPFYNNRPWRPA

LAMB3

291

Q13751
VGPLRCQGDRNYWNA

CNTNAP2

786

Q9UHC6
YDPRENSPYLRGNTW

ENAM

606

Q9NRM1
CPGAWLRKPYYLQAR

DIPK1A

6

Q5T7M9
DYQPSIEGPWLRACG

PRSS46P

21

E5RG02
SAPLVPCRGGWRYAQ

SLC22A3

121

O75751
CKGDWSRYNEARPPN

ISM1

426

B1AKI9
VQRVYQSCRWPGPCA

COL26A1

76

Q96A83
QSCRWPGPCANLVSY

COL26A1

81

Q96A83
PPREYALPFGWCRFN

NEURL4

1386

Q96JN8
ALPFGWCRFNLRVNP

NEURL4

1391

Q96JN8
CTWARGPTAPRDVQY

CSF2RA

136

P15509
SWPQVGRVEFRNYCL

ABCC1

1286

P33527
PPSNRYAGDWSVCGR

SYDE1

646

Q6ZW31
SAQPPQWRCYARLVN

SZT2

1116

Q5T011
APPSLRWYQRCQPSD

SLC35G3

21

Q8N808
CIPENPHNIYFGRWI

TRMT11

161

Q7Z4G4
WRAGEPYAGPQVFRC

SIGLEC15

81

Q6ZMC9
PRQCPCLVDGARYWP

SSPOP

1866

A2VEC9
QARCRYLQPRWTDFP

TIMM29

146

Q9BSF4
DWYRGNCRNQIGIFP

SH3D19

531

Q5HYK7
APSPRCRWGYQALSV

TMEM121B

191

Q9BXQ6
GCPWAYLSNRQRRFS

TAF1C

161

Q15572
LCEGLFDPYQTWRRQ

NBEAL2

141

Q6ZNJ1
ESGRWNDVPCNYNLP

NCAN

1191

O14594
WFRAGDRPYQDAPVA

SIGLEC8

66

Q9NYZ4
YQPPFLCQWGRHQPS

XBP1

241

P17861
ENYCRNPDGKRAPWC

PLG

321

P00747
LCNGPYWVRDGEVRF

SDF2

136

Q99470
VGLGNIWRFPYLCQT

SLC6A18

36

Q96N87
FLYARSCQNQWPEPR

AFAP1L1

541

Q8TED9
GPVYPWRSLRECQGA

CILP2

876

Q8IUL8
HPDGRWNDDVCQRPY

CLEC10A

286

Q8IUN9
VRGNELPRPIQYLCW

FAP

141

Q12884
YTWRLPCGGVRNPNQ

TNIP1

596

Q15025
PRPQGWLGVFLDYEC

TRIM77

401

I1YAP6
WGNPGFTCLYRVRVH

SUN5

346

Q8TC36
YDRACPARPCFVGEW

SBSPON

66

Q8IVN8
HSPYDRPGWNPRFCI

SYNGAP1

36

Q96PV0
PQAPALDYRVPRWCY

SRPX2

46

O60687
GSYGWRNFHPQCLQR

SLCO4C1

86

Q6ZQN7
NAVTGPCRASFPRWY

SPINT2

136

O43291
WAVQGSPYLCPQCRA

TRIM25

41

Q14258
RSEIPCYWENQPTGC

ZC3H11A

61

O75152
GQRLCVYGLASPPWR

THEMIS2

286

Q5TEJ8
SPYPAHARCQWALRG

ST14

236

Q9Y5Y6
REFYPSNLTPLWAGC

TREH

411

O43280
PCRDYPWRFKGASFN

PIEZO2

1191

Q9H5I5
CNQGPEYIERLPLRW

PHF19

246

Q5T6S3
GPFRYQENPRAAWLP

SEMA5B

401

Q9P283
RYFLLRQGVPNWDCD

MARS2

371

Q96GW9
LPQMCWDITYRFRGP

AVPR1A

106

P37288
RSEIPCYWENQPTGC

ZC3H11B

61

A0A1B0GTU1
VYFSPEEWGCLRPAQ

ZNF689

36

Q96CS4
PWAPPGRDYFCNRSA

ZNF217

891

O75362
RNRPDLYGPFWICAT

YIPF2

116

Q9BWQ6
PFQCPECSRGFFWRN

ZNF425

441

Q6IV72
DWQCPRTPYAASRDF

MST1R

26

Q04912
PRCDGHQQGYPRKWR

TRPV4

851

Q9HBA0
FWGAPCEQPLERRYQ

TMEM198

21

Q66K66
RHYFQQPPRCSLWSL

UNC79

1376

Q9P2D8