Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhyaluronoglucuronidase activity

HYAL3 HYAL2

6.02e-072162GO:0033906
GeneOntologyMolecularFunctionhyalurononglucosaminidase activity

HYAL3 HYAL2

2.16e-059162GO:0004415
GeneOntologyMolecularFunctionhexosaminidase activity

HYAL3 HYAL2

8.13e-0517162GO:0015929
GeneOntologyMolecularFunctioncopper ion binding

MUC2 PRND

1.74e-0378162GO:0005507
GeneOntologyMolecularFunctionvirus receptor activity

HYAL3 HYAL2

2.07e-0385162GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

HYAL3 HYAL2

2.12e-0386162GO:0140272
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

HYAL3 HYAL2

3.02e-03103162GO:0004553
GeneOntologyMolecularFunctionhydrolase activity, acting on glycosyl bonds

HYAL3 HYAL2

5.80e-03144162GO:0016798
GeneOntologyMolecularFunctioncytokine binding

COPS5 HYAL2

6.86e-03157162GO:0019955
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MUC2 MUC5AC

9.70e-03188162GO:0005201
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

CROT ZDHHC16

1.52e-02238162GO:0016747
GeneOntologyBiologicalProcessglycosaminoglycan catabolic process

HYAL3 HYAL2 GALNS

1.87e-0632163GO:0006027
GeneOntologyBiologicalProcessaminoglycan catabolic process

HYAL3 HYAL2 GALNS

3.18e-0638163GO:0006026
GeneOntologyBiologicalProcesscellular response to UV-B

HYAL3 HYAL2

3.71e-0512162GO:0071493
GeneOntologyBiologicalProcessmucopolysaccharide metabolic process

HYAL3 HYAL2 GALNS

5.91e-05100163GO:1903510
GeneOntologyBiologicalProcesshyaluronan catabolic process

HYAL3 HYAL2

8.57e-0518162GO:0030214
GeneOntologyBiologicalProcessglycosaminoglycan metabolic process

HYAL3 HYAL2 GALNS

1.04e-04121163GO:0030203
GeneOntologyBiologicalProcessresponse to UV-B

HYAL3 HYAL2

1.17e-0421162GO:0010224
GeneOntologyBiologicalProcessaminoglycan metabolic process

HYAL3 HYAL2 GALNS

1.35e-04132163GO:0006022
GeneOntologyBiologicalProcesshyaluronan metabolic process

HYAL3 HYAL2

4.33e-0440162GO:0030212
GeneOntologyBiologicalProcessacrosome reaction

PRND HYAL3

5.98e-0447162GO:0007340
GeneOntologyBiologicalProcesscellular response to cytokine stimulus

MUC19 WDR35 HYAL3 HYAL2 CCDC3

6.35e-04967165GO:0071345
GeneOntologyBiologicalProcessresponse to cytokine

MUC19 WDR35 HYAL3 HYAL2 CCDC3

1.06e-031083165GO:0034097
GeneOntologyBiologicalProcessresponse to peptide

MUC19 WDR35 HYAL3 HYAL2 CCDC3

1.14e-031100165GO:1901652
GeneOntologyCellularComponentGolgi lumen

MUC19 MUC2 MUC5AC MUC5B

1.21e-06109164GO:0005796
GeneOntologyCellularComponentmucus layer

MUC2 MUC5AC

1.65e-063162GO:0070701
DomainTIL

MUC19 MUC2 MUC5AC MUC5B

1.33e-1012154PF01826
DomainC8

MUC19 MUC2 MUC5AC MUC5B

1.33e-1012154PF08742
DomainC8

MUC19 MUC2 MUC5AC MUC5B

1.92e-1013154SM00832
DomainUnchr_dom_Cys-rich

MUC19 MUC2 MUC5AC MUC5B

1.92e-1013154IPR014853
DomainTIL_dom

MUC19 MUC2 MUC5AC MUC5B

2.68e-1014154IPR002919
DomainVWFD

MUC19 MUC2 MUC5AC MUC5B

4.87e-1016154PS51233
DomainVWD

MUC19 MUC2 MUC5AC MUC5B

4.87e-1016154SM00216
DomainVWF_type-D

MUC19 MUC2 MUC5AC MUC5B

4.87e-1016154IPR001846
DomainVWD

MUC19 MUC2 MUC5AC MUC5B

4.87e-1016154PF00094
DomainCTCK_1

MUC19 MUC2 MUC5AC MUC5B

8.19e-1018154PS01185
DomainVWC_out

MUC19 MUC2 MUC5AC MUC5B

1.04e-0919154SM00215
DomainCT

MUC19 MUC2 MUC5AC MUC5B

1.95e-0922154SM00041
DomainCys_knot_C

MUC19 MUC2 MUC5AC MUC5B

3.37e-0925154IPR006207
DomainCTCK_2

MUC19 MUC2 MUC5AC MUC5B

3.37e-0925154PS01225
DomainWxxW_domain

MUC2 MUC5AC MUC5B

8.37e-096153IPR025155
DomainMucin2_WxxW

MUC2 MUC5AC MUC5B

8.37e-096153PF13330
DomainVWC

MUC19 MUC2 MUC5AC MUC5B

1.96e-0838154SM00214
DomainVWFC_2

MUC19 MUC2 MUC5AC MUC5B

1.96e-0838154PS50184
DomainVWF_dom

MUC19 MUC2 MUC5AC MUC5B

2.96e-0842154IPR001007
DomainVWFC_1

MUC2 MUC5AC MUC5B

2.95e-0636153PS01208
DomainHyaluronidase

HYAL3 HYAL2

6.01e-065152IPR018155
DomainGlyco_hydro_56

HYAL3 HYAL2

6.01e-065152PF01630
DomainGlyco_hormone_CN

MUC5AC MUC5B

6.28e-0515152IPR006208
DomainCys_knot

MUC5AC MUC5B

6.28e-0515152PF00007
DomainVWC

MUC5AC MUC5B

2.25e-0428152PF00093
Domain-

HYAL3 HYAL2

5.09e-04421523.20.20.70
DomainAldolase_TIM

HYAL3 HYAL2

5.59e-0444152IPR013785
DomainGlycoside_hydrolase_SF

HYAL3 HYAL2

8.10e-0453152IPR017853
DomainEGF

HYAL3 HYAL2

1.49e-02235152SM00181
DomainEGF_3

HYAL3 HYAL2

1.49e-02235152PS50026
DomainEGF-like_dom

HYAL3 HYAL2

1.66e-02249152IPR000742
DomainEGF_1

HYAL3 HYAL2

1.73e-02255152PS00022
DomainEGF-like_CS

HYAL3 HYAL2

1.81e-02261152IPR013032
DomainEGF_2

HYAL3 HYAL2

1.86e-02265152PS01186
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC19 MUC2 MUC5AC MUC5B

2.58e-0921134MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC19 MUC2 MUC5AC MUC5B

2.06e-0760134MM15636
PathwayKEGG_GLYCOSAMINOGLYCAN_DEGRADATION

HYAL3 HYAL2 GALNS

8.07e-0721133M3624
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC19 MUC2 MUC5AC MUC5B

2.29e-06109134MM15164
PathwayKEGG_MEDICUS_REFERENCE_DERMATAN_SULFATE_DEGRADATION

HYAL3 HYAL2

2.19e-058132M47607
PathwayREACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION

HYAL3 HYAL2

5.15e-0512132M660
PathwayREACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION

HYAL3 HYAL2

5.15e-0512132MM14868
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC5AC MUC5B

9.35e-0516132M27410
PathwayREACTOME_HYALURONAN_METABOLISM

HYAL3 HYAL2

1.06e-0417132M666
PathwayREACTOME_HYALURONAN_METABOLISM

HYAL3 HYAL2

1.06e-0417132MM14864
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC5AC MUC5B

1.06e-0417132M27412
PathwayWP_GLYCOSAMINOGLYCAN_DEGRADATION

HYAL2 GALNS

1.06e-0417132M39832
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

HYAL3 HYAL2 GALNS

1.74e-04123133MM14623
PathwayREACTOME_GLYCOSAMINOGLYCAN_METABOLISM

HYAL3 HYAL2 GALNS

1.87e-04126133M695
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5AC MUC5B

1.96e-0423132M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC5AC MUC5B

2.52e-0426132M27483
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

MUC19 MUC2 MUC5AC PRND COPS5 MUC5B

8.44e-041389136MM15307
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC5AC MUC5B GALNS

1.38e-03250133M27554
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC5AC MUC5B

1.44e-0362132M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC5AC MUC5B

1.73e-0368132M27303
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

HYAL3 HYAL2 GALNS

1.74e-03271133MM15406
PathwayREACTOME_METABOLISM_OF_CARBOHYDRATES

HYAL3 HYAL2 GALNS

2.07e-03288133M16864
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC5AC MUC5B

4.53e-03111132M27416
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC5AC MUC5B

7.11e-03140132M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC5AC MUC5B

7.41e-03143132M27275
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC2 MUC5AC MUC5B

4.48e-13616419110483
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC2 MUC5AC MUC5B

7.99e-11316319718741
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC19 MUC2 MUC5AC MUC5B

9.10e-111816418834073
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC2 MUC5AC MUC5B

3.19e-10416325638393
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC2 MUC5AC MUC5B

3.19e-10416317471237
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC2 MUC5AC MUC5B

3.19e-10416322269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC2 MUC5AC MUC5B

3.19e-10416314984930
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC2 MUC5AC MUC5B

3.19e-10416312676567
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC2 MUC5AC MUC5B

3.19e-10416323807779
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC2 MUC5AC MUC5B

3.19e-10416329869461
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC2 MUC5AC MUC5B

7.98e-10516311062147
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC2 MUC5AC MUC5B

7.98e-10516316188033
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5AC MUC5B

1.98e-0721627513696
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5AC MUC5B

1.98e-07216223272068
Pubmed

Intestinal MUC2 and gastric M1/MUC5AC in preneoplastic lesions induced by 1,2-dimethylhydrazine in rat: a sequential analysis.

MUC2 MUC5AC

1.98e-07216217203232
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5AC MUC5B

1.98e-07216224327612
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5AC MUC5B

1.98e-07216231030254
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5AC MUC5B

1.98e-07216226871672
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5AC MUC5B

1.98e-07216227729120
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.

MUC2 MUC5AC

1.98e-07216223832517
Pubmed

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution.

MUC2 MUC5AC

1.98e-07216223832516
Pubmed

Altered expression of MUC2 and MUC5AC in progression of colorectal carcinoma.

MUC2 MUC5AC

1.98e-07216220731025
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC2 MUC5B

1.98e-07216220873538
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5AC MUC5B

1.98e-07216221653907
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5AC MUC5B

1.98e-07216234058148
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5AC MUC5B

1.98e-07216237146737
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5AC MUC5B

1.98e-07216223527003
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5AC MUC5B

1.98e-07216214988081
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5AC MUC5B

1.98e-07216236427316
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5AC MUC5B

1.98e-07216216540890
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5AC MUC5B

1.98e-07216215563276
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5AC MUC5B

1.98e-07216236111525
Pubmed

Temporal analysis of goblet cells and mucin gene expression in murine models of allergic asthma.

MUC2 MUC5AC

1.98e-07216214594655
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5AC MUC5B

1.98e-07216232348677
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5AC MUC5B

1.98e-07216217621824
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5AC MUC5B

1.98e-07216211587997
Pubmed

Muc5b is required for airway defence.

MUC5AC MUC5B

1.98e-07216224317696
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5AC MUC5B

1.98e-07216227845589
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5AC MUC5B

1.98e-07216228607090
Pubmed

In vivo glycosylation of mucin tandem repeats.

MUC2 MUC5AC

1.98e-07216211445551
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5AC MUC5B

1.98e-07216222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5AC MUC5B

1.98e-07216214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5AC MUC5B

1.98e-07216235776514
Pubmed

Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.

MUC2 MUC5AC

1.98e-07216212527922
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5AC MUC5B

1.98e-07216224332705
Pubmed

Abnormal subcellular distribution of mature MUC2 and de novo MUC5AC mucins in adenomas of the rectum: immunohistochemical detection using non-VNTR antibodies to MUC2 and MUC5AC peptide.

MUC2 MUC5AC

1.98e-07216212820724
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5AC MUC5B

1.98e-07216227435107
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5AC MUC5B

1.98e-07216234656442
Pubmed

Mucolytic activity of bacterial and human chitinases.

MUC2 MUC5AC

1.98e-07216217321686
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5AC MUC5B

5.95e-07316236675209
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5AC MUC5B

5.95e-07316227776277
Pubmed

Differences in the expression of mucins in various forms of cystitis glandularis.

MUC2 MUC5AC

5.95e-07316217659847
Pubmed

Mammalian hyaluronidase induces ovarian granulosa cell apoptosis and is involved in follicular atresia.

HYAL3 HYAL2

5.95e-07316218653706
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5AC MUC5B

5.95e-07316219556605
Pubmed

Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation.

HYAL3 HYAL2

5.95e-07316211296287
Pubmed

Expression and cellular localization of human hyaluronidase-2 in articular chondrocytes and cultured cell lines.

HYAL3 HYAL2

5.95e-07316216600643
Pubmed

Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.

MUC2 MUC5AC

5.95e-07316218300795
Pubmed

Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.

MUC2 MUC5AC

5.95e-07316223464473
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5AC MUC5B

5.95e-07316221455588
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5AC MUC5B

5.95e-07316234158522
Pubmed

Human hyaluronidases: electrophoretic multiple forms in somatic tissues and body fluids. Evidence for conserved hyaluronidase potential N-glycosylation sites in different mammalian species.

HYAL3 HYAL2

5.95e-07316210989127
Pubmed

Involvement of hyaluronidases in colorectal cancer.

HYAL3 HYAL2

5.95e-07316220849597
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5AC MUC5B

5.95e-07316229802623
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5AC MUC5B

5.95e-07316220422702
Pubmed

Meconium ileus in cystic fibrosis is not linked to central repetitive region length variation in MUC1, MUC2, and MUC5AC.

MUC2 MUC5AC

5.95e-07316224920497
Pubmed

Ultraviolet-B irradiation induces differential regulations of hyaluronidase expression and activity in normal human keratinocytes.

HYAL3 HYAL2

5.95e-07316221699545
Pubmed

Gene expression profiling of colorectal mucinous adenocarcinomas.

MUC2 MUC5AC

5.95e-07316220485009
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5AC MUC5B

5.95e-07316229604272
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5AC MUC5B

5.95e-07316229286856
Pubmed

Expression and activity of hyaluronidases HYAL-1, HYAL-2 and HYAL-3 in the human intervertebral disc.

HYAL3 HYAL2

5.95e-07316231758257
Pubmed

Expression and regulation patterns of hyaluronidases in small cell lung cancer and glioma lines.

HYAL3 HYAL2

5.95e-07316212684632
Pubmed

Cadherin-catenin adhesion system and mucin expression: a comparison between young and older patients with gastric carcinoma.

MUC2 MUC5AC

5.95e-07316218825309
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5AC MUC5B

5.95e-07316219596978
Pubmed

Hyaluronidase expression and activity is regulated by pro-inflammatory cytokines in human airway epithelial cells.

HYAL3 HYAL2

5.95e-07316218390475
Pubmed

Expression of aberrant mucins in lobular carcinoma with histiocytoid feature of the breast.

MUC2 MUC5AC

5.95e-07316217333267
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC2 MUC5AC MUC5B

8.42e-074116322675208
Pubmed

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis.

MUC2 MUC5B

1.19e-06416221596555
Pubmed

Evaluation of MUC1, MUC2, MUC5AC, and MUC6 Expression Differences in Lung Adenocarcinoma Subtypes by Using a Final Immunoreactivity Score (FIRS).

MUC2 MUC5AC

1.19e-06416236367122
Pubmed

PGE(2) induces MUC2 and MUC5AC expression in human intrahepatic biliary epithelial cells via EP4/p38MAPK activation.

MUC2 MUC5AC

1.19e-06416223619266
Pubmed

MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.

MUC5AC MUC5B

1.19e-06416221097527
Pubmed

Hyaluronidases and CD44 undergo differential modulation during chondrogenesis.

HYAL3 HYAL2

1.19e-06416211944887
Pubmed

TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.

MUC5AC MUC5B

1.19e-06416223249391
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

MUC2 MUC5AC

1.19e-06416222691042
Pubmed

Mucin expression profile in Barrett's, dysplasia, adenocarcinoma sequence in the esophagus.

MUC2 MUC5AC

1.19e-06416217401217
Pubmed

Associations between the expression of mucins (MUC1, MUC2, MUC5AC and MUC6) and clinicopathologic parameters of human breast carcinomas.

MUC2 MUC5AC

1.19e-06416233154304
Pubmed

Structural organization and chromosomal localization of Hyal2, a gene encoding a lysosomal hyaluronidase.

HYAL3 HYAL2

1.19e-0641629790770
Pubmed

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

MUC5AC MUC5B

1.19e-06416231582416
Pubmed

Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells.

MUC2 MUC5AC

1.19e-06416212391274
Pubmed

CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2.

HYAL3 HYAL2

1.19e-06416217170110
Pubmed

Gastric mucin expression in first-degree relatives of gastric cancer patients.

MUC2 MUC5AC

1.19e-06416224901817
Pubmed

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.

MUC5AC MUC5B

1.19e-06416218258655
Pubmed

[Expression and clinical significance of Mucin and E-cadherin in colorectal tumors].

MUC2 MUC5AC

1.19e-06416217991319
Pubmed

Expression profile of mucins (MUC1, MUC2, MUC5AC, and MUC6) in ovarian mucinous tumours: changes in expression from benign to malignant tumours.

MUC2 MUC5AC

1.19e-06416225298197
Pubmed

Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?

MUC2 MUC5AC

1.19e-06416220929551
Pubmed

MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance.

MUC2 MUC5AC

1.19e-06416227298226
Pubmed

Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.

MUC2 MUC5B

1.98e-06516224840470
Pubmed

Molecular cloning and characterization of a novel member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12.

MUC2 MUC5AC

1.98e-06516212135769
Pubmed

pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins.

MUC2 MUC5AC

1.98e-06516210611155
Pubmed

Divergent expression of MUC5AC, MUC6, MUC2, CD10, and CDX-2 in dysplasia and intramucosal adenocarcinomas with intestinal and foveolar morphology: is this evidence of distinct gastric and intestinal pathways to carcinogenesis in Barrett Esophagus?

MUC2 MUC5AC

1.98e-06516222261707
Pubmed

Cloning and characterization of a novel UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, pp-GalNAc-T14.

MUC2 MUC5AC

1.98e-06516212507512
Cytoband11p15.5

MUC2 MUC5AC MUC5B

9.05e-0611816311p15.5
Cytoband3p21.3

HYAL3 HYAL2

1.93e-04591623p21.3
CytobandEnsembl 112 genes in cytogenetic band chr11p15

MUC2 MUC5AC MUC5B

9.17e-04564163chr11p15
CytobandEnsembl 112 genes in cytogenetic band chr3p21

HYAL3 HYAL2

5.32e-03316162chr3p21
GeneFamilyCD molecules|Mucins

MUC19 MUC2 MUC5AC MUC5B

2.81e-1021104648
CoexpressionNABA_ECM_AFFILIATED

MUC19 MUC2 MUC5AC MUC5B

2.19e-06158164MM17063
CoexpressionNABA_ECM_AFFILIATED

MUC19 MUC2 MUC5AC MUC5B

2.93e-06170164M5880
CoexpressionNABA_MATRISOME_ASSOCIATED

MUC19 MUC2 MUC5AC MUC5B HYAL3 HYAL2

3.07e-06738166MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

MUC19 MUC2 MUC5AC MUC5B HYAL3 HYAL2

3.40e-06751166M5885
CoexpressionNABA_MATRISOME

MUC19 MUC2 MUC5AC MUC5B HYAL3 HYAL2

1.83e-051008166MM17056
CoexpressionNABA_MATRISOME

MUC19 MUC2 MUC5AC MUC5B HYAL3 HYAL2

2.03e-051026166M5889
CoexpressionGSE6875_TCONV_VS_TREG_UP

PRND HYAL3 ATE1

2.21e-04198163M6799
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_SCG3_POS_LYMPHATIC_ENDOTHELIAL_CELL

HYAL3 CROT CCDC3 GALNS

4.08e-04604164M45760
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B CSMD1

2.26e-05157163c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

MUC5AC MUC5B GRIK3

2.71e-051671636efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B CROT

3.23e-05177163a235ff4f37a7622216526191efc4832fb8ed6957
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B GRIK3 CSMD1

3.62e-05184163ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B GRIK3 CSMD1

3.62e-051841632cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B GRIK3 CSMD1

3.62e-051841632b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC2 MUC5B ATE1

3.68e-05185163ef3c1fd52d21d96f81fb0e5097b24be0ce16e222
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MUC2 MUC5B ATE1

3.68e-05185163c357fa098b561da16c9fa82b0c3563b5cd3fa875
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC2 MUC5AC MUC5B

4.44e-05197163da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC5AC MUC5B HYAL2

4.44e-05197163a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC2 MUC5AC MUC5B

4.44e-05197163a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCelldistal-Epithelial-Goblet-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC2 MUC5AC MUC5B

4.44e-051971633fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-goblet|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5AC MUC5B

4.51e-051981639c5d7852f03468394e726c444cac92a043fc6d0e
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MUC2 MUC5AC MUC5B

4.51e-05198163484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5AC MUC5B

4.51e-05198163f95f38cc747fb3549a791288bf8d0518c049ac96
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_and_Papillary_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

MUC2 PRND

6.34e-04105162cfd271e2cd004d6815bcc3ce7cad86fe62b5299b
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-double-positive,_alpha-beta_thymocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC5AC MUC5B

8.40e-0412116225fa58d8e07dab572b2ba8e23c9d1ad3502dfc56
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GRIK3 CCDC3

1.03e-0313416264979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous|TCGA-Stomach / Sample_Type by Project: Shred V9

MUC2 PRND

1.07e-03137162291b4eeaf21ec951695621161dbc2de3e82ca993
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-2|TCGA-Brain / Sample_Type by Project: Shred V9

MUC2 ATE1

1.11e-031391626f6c64eaa1ce84e0aa9a0caa9c4d9bf7afe626df
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC2 MUC5AC

1.15e-031421627fa6b0f493634d25d68b4365b8c82cd43f5d31db
ToppCellCiliated_cells-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MUC5B CSMD1

1.22e-0314616220f080318e9cbfd9b8b90a5e9f704d6d85b969ee
ToppCellClub_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B

1.23e-031471625a824c89e4d045af465d7333275f8191fb29b041
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3|TCGA-Stomach / Sample_Type by Project: Shred V9

MUC2 PRND

1.25e-03148162c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC5B CSMD1

1.27e-03149162a22417286de8606f0cc94f86b70bce17aeefb9c2
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

GRIK3 CSMD1

1.27e-031491626e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC5B CSMD1

1.27e-03149162c5eedb54ef2e0f131aa6730612c921bc19479632
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B

1.27e-0314916281c813588bb5efb7b31141a75d387210dcb76094
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MUC2 HYAL3

1.35e-03154162e65e4636646164610f33f7bbac0d879a3ea55986
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.37e-0315516262b59cb32b12bd55b19e98786a866d788fc9e4bf
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-5|TCGA-Colorectal / Sample_Type by Project: Shred V9

MUC2 MUC5AC

1.41e-031571625fb41af247465aa29aa7b8edd26e3d3794766f80
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC5AC MUC5B

1.42e-0315816203281e87780e3bacd089903383c016d03c373bf7
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.44e-0315916260b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-7|TCGA-Cervix / Sample_Type by Project: Shred V9

MUC5AC MUC5B

1.44e-0315916275a82bbabd97b168dbf1c3f43a9bdad48ce18c78
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 MUC5B

1.46e-03160162c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 MUC5B

1.46e-0316016225c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRND HYAL2

1.48e-031611622a721b6228045adb2dfbcd4990d371f961dc5dc2
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5B GRIK3

1.48e-031611622d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC5AC MUC5B

1.50e-03162162fe546c2272a70bb5f08e6e097b9accdb891eda23
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CROT GALNS

1.50e-031621626972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_dendritic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC2 MUC5AC

1.50e-03162162233011408f022647932c81ebab78f9813e3c6833
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC19 HYAL3

1.50e-0316216225bb1b9709f960fdf90faff56e874f52a8f5d17e
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B HYAL3

1.51e-03163162f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B HYAL3

1.51e-03163162a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell5'-Airway_Nasal_SMG-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B HYAL3

1.51e-03163162454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B HYAL3

1.51e-03163162be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell5'-Airway_Nasal_SMG|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B HYAL3

1.51e-03163162d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B HYAL3

1.51e-03163162d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

MUC2 MUC5AC

1.53e-031641623c15e9b8403b03d67f6ecd7861dc19f1261e3244
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.53e-03164162911081739174ec68bc0893c804e4276b206bea7d
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.53e-03164162c5bfae7e9497185548c243d6f9ebadbcef48ba7f
ToppCellAdult-Epithelial-lung_goblet_cell-D175|Adult / Lineage, Cell type, age group and donor

MUC5AC MUC5B

1.53e-031641626e6aedb61f8e195d52e028fdda750a29bb14e57e
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.53e-0316416276b0ac220b7ca22fbea28a507f01f96ae9f53932
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC5AC MUC5B

1.55e-03165162baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCellClub-club-12|World / Class top

MUC5AC MUC5B

1.55e-031651629b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC5AC MUC5B

1.55e-03165162dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCellPND14-Epithelial-Epithelial_Airway-Neurosecretory|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC5AC MUC5B

1.55e-031651626fdce8b23736409a23884ef3918638ffc067a86f
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.57e-0316616260060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.57e-03166162ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.57e-031661624586d6725403f879fc96f67be579022587ce1906
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.59e-0316716231633899aae852873a4887e72c621474b0a51a33
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC CCDC3

1.59e-03167162805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC CCDC3

1.59e-0316716231cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC CCDC3

1.59e-031671623acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRND HYAL2

1.61e-0316816237249f38f8f04ec5743097259de67b106ca2b02f
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.61e-03168162b275e951ff7109e36da22fc17bd4516f9b9432c4
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.61e-03168162a0dbe2ee697e29b32aa5f8326445e067ff66c154
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CROT GALNS

1.61e-0316816235ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.61e-031681620757a5af953901a8faed5774ffec4755fc9c0a6e
ToppCellClub_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B

1.63e-0316916203b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.63e-031691621a684471dbda42e1470e5a889648666e14f25982
ToppCellfacs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CROT GALNS

1.63e-03169162ee27bcfe3f9a295ec5fb0a375d77d1050e5cbaad
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC5AC MUC5B

1.63e-03169162a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCellfacs-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CROT GALNS

1.63e-03169162922086f218135b734b7d370b871923e50141edce
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.63e-03169162db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.63e-0316916297b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRND CCDC3

1.63e-031691620d8b681404e18f3061d84425fb5f7d84e8e2b8d7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRND HYAL2

1.64e-031701626eb86352739e6fd3cb914e9a16505ac629970b66
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CROT CSMD1

1.64e-031701622d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B

1.64e-031701622c5a1469e5743870e96e6c2cc92f0c5096b79f51
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CROT CSMD1

1.64e-031701620cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B

1.64e-031701629bea81031cdfe45e8cddac3a3afd9ca6c331c45a
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.66e-03171162eddc5e05003382603ee49f74b9e2242a43021096
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MUC5AC CROT

1.66e-0317116259b9dbaa05b6e5740edc633c9ce1181565550d5b
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5B

1.66e-0317116248125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma|TCGA-Cervix / Sample_Type by Project: Shred V9

MUC5AC MUC5B

1.66e-031711621af575809b3334bfaa019ff26c56e6cb03c82ee8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MUC19 GRIK3

1.66e-03171162fdd96c6fe850bd10e1e0d0f18c4401f8348b7d2c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MUC5AC CROT

1.66e-03171162a5b9dd2b6a54db7962beeb5a9ceb9dacfb613fa7
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5AC MUC5B

1.68e-031721620be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell11.5-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

MUC2 MUC5AC

1.68e-031721629d4d92e2d16dfc8a394f2641653bb97de20a2530
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC19 HYAL2

1.68e-03172162de9b11ab109d04937186c09772cec9105a935f95
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.70e-03173162e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MUC19 PRND

1.70e-031731623a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.70e-031731623aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC5AC MUC5B

1.70e-03173162464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5AC MUC5B

1.70e-03173162e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC5AC MUC5B

1.72e-031741627d2f802f493f19a068e097b2909a9000e2160266
ToppCell5'-GW_trimst-1.5-LargeIntestine-Epithelial-goblet|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC2 MUC5AC

1.72e-03174162e7cca4b6a3935fad61cf2a3d9984ab1ffa1a9447
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIK3 CCDC3

1.72e-03174162a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HYAL2 CCDC3

1.72e-0317416218ab52d8bbca0507fee220e0c4fc765fc47dda34
Drug4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid

MUC2 MUC5AC

1.29e-058162ctd:C064545
Drug4-hydroxyretinoic acid

MUC2 MUC5AC

3.04e-0512162ctd:C019429
Diseasecystitis (is_marker_for)

MUC2 MUC5AC

2.41e-072152DOID:1679 (is_marker_for)
Diseasesputum mucin-5B amount

MUC2 MUC5AC

7.23e-073152OBA_2050332
Diseasemucinous adenocarcinoma (is_marker_for)

MUC2 MUC5AC

2.41e-065152DOID:3030 (is_marker_for)
Diseasecystic fibrosis (is_marker_for)

MUC2 MUC5AC MUC5B

3.95e-0662153DOID:1485 (is_marker_for)
Diseasecholangiocarcinoma (is_marker_for)

MUC2 MUC5AC MUC5B

4.35e-0664153DOID:4947 (is_marker_for)
Diseaseinterstitial lung disease

MUC5AC MUC5B CSMD1

4.99e-0667153EFO_0004244
Diseasebringing up phlegm, sputum or mucus on most days, self-reported

MUC2 MUC5AC

8.67e-069152EFO_0009824
Diseasepulmonary fibrosis

MUC5AC MUC5B

1.32e-0511152EFO_0009448
DiseaseSjogren's syndrome (is_marker_for)

MUC19 MUC5AC

6.61e-0524152DOID:12894 (is_marker_for)
Diseaseliver cirrhosis (biomarker_via_orthology)

WDR35 MUC2

1.34e-0434152DOID:5082 (biomarker_via_orthology)
DiseaseCOVID-19 symptoms measurement

MUC5AC MUC5B

1.42e-0435152EFO_0600019
Diseasepneumonia

MUC2 MUC5AC

2.57e-0447152EFO_0003106
Diseasereaction time measurement

MUC19 GRIK3 CCDC3 CSMD1

2.75e-04658154EFO_0008393
Diseaseidiopathic pulmonary fibrosis

MUC5AC MUC5B

3.79e-0457152EFO_0000768
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5AC MUC5B

4.34e-0461152DOID:3587 (is_marker_for)
Diseaseatypical femoral fracture, response to bisphosphonate

GALNS CSMD1

5.39e-0468152EFO_0009958, EFO_0009960
Diseasewellbeing measurement, alcohol consumption measurement

CCDC3 ATE1

6.38e-0474152EFO_0007869, EFO_0007878
DiseaseInhalant adrenergic use measurement

MUC2 MUC5AC

1.07e-0396152EFO_0009941
Diseasechronic obstructive pulmonary disease (is_marker_for)

MUC5AC MUC5B

1.09e-0397152DOID:3083 (is_marker_for)
Diseasesusceptibility to pneumonia measurement

MUC5AC MUC5B

1.09e-0397152EFO_0008410
Diseaseneurotic disorder

GRIK3 CSMD1

1.18e-03101152EFO_0004257
Diseasepeptide measurement

HYAL3 CSMD1

1.38e-03109152EFO_0010520
Diseaseadult onset asthma

MUC2 MUC5AC

1.61e-03118152EFO_1002011
Diseaseasthma (is_marker_for)

MUC5AC MUC5B

1.83e-03126152DOID:2841 (is_marker_for)
Diseaserespiratory system disease

MUC2 MUC5AC

2.41e-03145152EFO_0000684
Diseasealcohol dependence

MUC2 MUC5AC

3.81e-03183152MONDO_0007079
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

GRIK3 CSMD1

4.53e-03200152EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351

Protein segments in the cluster

PeptideGeneStartEntry
ENAIGWYHSHPGYGC

COPS5

131

Q92905
PGFPHGYPNYANCTW

CSMD1

46

Q96PZ7
DFYNPHGGCEWHYQP

MUC5B

1156

Q9HC84
HLWGFYLFPDCYNHD

HYAL2

201

Q12891
DYYNAPGECRWHYEP

MUC19

1541

Q7Z5P9
CDYYNPPHECEWHYE

MUC2

1121

Q02817
YCHAVWGDPDSPNYH

LMLN2

121

A0A1B0GTW7
DYYNPEGQCEWHYQP

MUC5AC

1166

P98088
FDEWFGSPNCHFGPY

GALNS

156

P34059
HLPWQYHAGQGGLFY

CCDC3

61

Q9BQI4
LWGFYHYPACGNGWH

HYAL3

196

O43820
NGPDCGYGSFHQQYW

ATE1

331

O95260
FSPYEWYDAHPCNPG

GRIK3

586

Q13003
VNFAGPAAHFEHYWP

CROT

101

Q9UKG9
NYWQFPDGIHYNGCS

PRND

81

Q9UKY0
PWLNNCVGHYNHRYF

ZDHHC16

186

Q969W1
HWYHGTEGYVEPDCP

WDR35

211

Q9P2L0