Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainZnF_C2HC

FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

5.00e-08551177SM00343
DomainZnf_CCHC

FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

5.00e-08551177IPR001878
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

5.06e-05121173PF15371
DomainDUF4599

SPATA31D4 SPATA31D1 SPATA31D3

5.06e-05121173IPR027970
DomainFAM47

FAM47A FAM47C

2.32e-0441172PF14642
DomainFAM47

FAM47A FAM47C

2.32e-0441172IPR032743
Pubmed

Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.

FAM90A14 FAM90A1 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

1.82e-23251281217684299
Pubmed

Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10

3.50e-19231281018602769
Pubmed

Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.

AOC1 FAM90A14 FAM90A1 FAM90A17 FAM90A19 FAM90A22 FAM90A26 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A10

1.19e-121641281222967998
Pubmed

Human transcription factor protein interaction networks.

MYC BRIX1 ZNF609 UBAP2 DEAF1 DHX37 BAG5 GON4L SRCAP CIT SIRT1 YEATS2 KMT2C NCOR2 RIF1 SALL1 PAX8 SEC16A OTUD4 YY1AP1 LTV1

6.16e-0814291282135140242
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

ZNF609 GON4L FAM90A1 YEATS2 KMT2C NCOR2 SALL1 SEC16A YY1AP1 RPL3

2.35e-063981281035016035
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SPEG GON4L CSMD3 YEATS2 ITSN2 SEC16A NAV1 OTUD4 YY1AP1 LRRC7

2.87e-064071281012693553
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

MYC BRIX1 ZNF609 DEAF1 TRA2B CHAF1A SRCAP HNRNPC YEATS2 KMT2C NCOR2 ZNF106 RIF1 ZBTB39 KIF18B RPL3 SLC27A4

5.66e-0612941281730804502
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DEAF1 CHAF1A HDAC7 HNRNPC SIRT1 YEATS2 NCOR2 ZNF106 RIF1 SEC16A OTUD4 YY1AP1 PRG4

6.01e-067741281315302935
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

TRA2B HNRNPC YEATS2 ITSN2 SEC16A LTV1

7.24e-06125128629467281
Pubmed

Involvement of SIRT1 in hypoxic down-regulation of c-Myc and β-catenin and hypoxic preconditioning effect of polyphenols.

MYC SIRT1

1.34e-052128222245592
Pubmed

Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism.

INSR LRP5

1.34e-052128228938444
Pubmed

Newly identified Gon4l/Udu-interacting proteins implicate novel functions.

GON4L YY1AP1

1.34e-052128232848183
Pubmed

Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution.

ERVV-2 ERVV-1

1.34e-052128218826608
Pubmed

The transcriptional regulator GON4L is required for viability and hematopoiesis in mice.

GON4L YY1AP1

1.34e-052128233864850
Pubmed

SirT1 knockdown potentiates radiation-induced bystander effect through promoting c-Myc activity and thus facilitating ROS accumulation.

MYC SIRT1

1.34e-052128225772107
Pubmed

Heterogeneous nuclear ribonucleoprotein C modulates translation of c-myc mRNA in a cell cycle phase-dependent manner.

MYC HNRNPC

1.34e-052128212509468
Pubmed

Low NCOR2 levels in multiple myeloma patients drive multidrug resistance via MYC upregulation.

MYC NCOR2

1.34e-052128234864816
Pubmed

Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.

ERVV-2 ERVV-1

1.34e-052128223555306
Pubmed

SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition.

MYC SIRT1

1.34e-052128226655722
Pubmed

SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas.

MYC SIRT1

1.34e-052128223024800
Pubmed

The Justy mutation identifies Gon4-like as a gene that is essential for B lymphopoiesis.

GON4L YY1AP1

1.34e-052128220530203
Pubmed

A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.

MYC SIRT1

1.34e-052128219364925
Pubmed

Up-regulation of c-MYC and SIRT1 expression correlates with malignant transformation in the serrated route to colorectal cancer.

MYC SIRT1

1.34e-052128223045412
Pubmed

Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication.

PLK2 SIRT1

1.34e-052128230517871
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

MYC BRIX1 TRA2B DHX37 CHAF1A HDAC7 HNRNPC KMT2C SUSD2 GYS1 OTUD4 LRRC7 POLQ RPL3 SLC27A4 STK25

2.08e-0512841281617353931
Pubmed

ATRX proximal protein associations boast roles beyond histone deposition.

SIRT1 ZNF106 SALL1 LTV1 KIF18B

2.25e-0591128534780483
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

PCDH11Y SHANK3 PCNX2 SPATA31D4 SPATA31D3 KMT2C RIF1

2.63e-05233128737704626
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

SDK2 GON4L PCARE HNRNPC LPIN3 FAT2 LTV1

2.70e-05234128736243803
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

BRIX1 TRA2B CHAF1A GON4L SRCAP CEP43 CCDC66 SEC16A NAV1 PPP1R9B KIF18B

2.81e-056451281125281560
Pubmed

High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.

INSR BIRC6 RIF1 NAV1

3.54e-0550128429560723
Pubmed

Tagging genes with cassette-exchange sites.

BIRC6 CIT SIRT1 DMXL1 KMT2C NCOR2 RIF1 KDM7A

3.58e-05335128815741177
Pubmed

Early B Cell Progenitors Deficient for GON4L Fail To Differentiate Due to a Block in Mitotic Cell Division.

GON4L YY1AP1

4.02e-053128228381640
Pubmed

A novel TRPM7/O-GlcNAc axis mediates tumour cell motility and metastasis by stabilising c-Myc and caveolin-1 in lung carcinoma.

MYC TRPM7

4.02e-053128232684624
Pubmed

PRMT6 deficiency induces autophagy in hostile microenvironments of hepatocellular carcinoma tumors by regulating BAG5-associated HSC70 stability.

BAG5 PRMT6

4.02e-053128233186656
Pubmed

MUC16-mediated activation of mTOR and c-Myc reprograms pancreatic cancer metabolism.

MYC MUC16

4.02e-053128226046375
Pubmed

Genome-wide association study identifies 5q21 and 9p24.1 (KDM4C) loci associated with alcohol withdrawal symptoms.

KDM4C FSIP2

4.02e-053128222072270
Pubmed

SIRT1 promotes thyroid carcinogenesis driven by PTEN deficiency.

MYC SIRT1

4.02e-053128222986535
Pubmed

Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1.

MYC SIRT1

4.02e-053128223797802
Pubmed

SirT1 regulates radiosensitivity of hepatoma cells differently under normoxic and hypoxic conditions.

MYC SIRT1

4.02e-053128222448750
Pubmed

SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.

MYC SIRT1

4.02e-053128225280219
Pubmed

Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia.

MYC NTRK3

4.02e-053128215198123
Pubmed

Sirt1 deacetylates c-Myc and promotes c-Myc/Max association.

MYC SIRT1

4.02e-053128221807113
Pubmed

Overexpression of GYS1, MIF, and MYC is associated with adverse outcome and poor response to azacitidine in myelodysplastic syndromes and acute myeloid leukemia.

MYC GYS1

4.02e-053128225487600
Pubmed

Up-regulation of INSR/IGF1R by C-myc promotes TSCC tumorigenesis and metastasis through the NF-κB pathway.

MYC INSR

4.02e-053128229518496
Pubmed

SIRT1 Activation Attenuates Bone Cancer Pain by Inhibiting mGluR1/5.

GRM1 SIRT1

4.02e-053128231270711
Pubmed

Inhibition of KDM4C/c-Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism.

MYC KDM4C

4.02e-053128235343073
Pubmed

The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation.

GON4L YY1AP1

4.02e-053128223608756
Pubmed

MYC promotes the development of papillary thyroid carcinoma by inhibiting the expression of lncRNA PAX8‑AS1:28.

MYC PAX8

4.02e-053128230720110
Pubmed

Roles of silent information regulator 1-serine/arginine-rich splicing factor 10-lipin 1 axis in the pathogenesis of alcohol fatty liver disease.

TRA2B SIRT1

4.02e-053128228467182
Pubmed

Diet-induced obesity promotes murine gastric cancer growth through a nampt/sirt1/c-myc positive feedback loop.

MYC SIRT1

4.02e-053128223970286
Pubmed

The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.

MYC SIRT1

4.02e-053128222190494
Pubmed

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.

MYC ZNF609 UBAP2 TRA2B HNRNPC SEC16A RPL3

5.27e-05260128736199071
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KCTD9 UBAP2 TRA2B GRM1 CIT SHANK3 NCOR2 KCNB1 SEC16A NAV1 OTUD4 PPP1R9B LRRC7

5.85e-059631281328671696
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPEG ANKLE1 SRCAP BIRC6 CIT HDAC7 PCNX2 LPIN3 KMT2C NCOR2 SEC16A NAV1 LRP5 PDZD8

5.93e-0511051281435748872
Pubmed

Protein phosphatase 1γ isoforms linked interactions in the brain.

DEAF1 SHANK3 RIF1 PPP1R9B

5.94e-0557128423080069
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

SECISBP2L BRIX1 TRA2B HNRNPC RIF1 NAV1 PPP1R9B RPL3

6.05e-05361128830344098
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM4C KMT2C KDM7A

6.17e-0521128327626377
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

MYC BRIX1 TRA2B DHX37 CHAF1A HNRNPC NCOR2 ZNF106 RIF1 PDZD8 KIF18B RPL3 SLC27A4

7.64e-059891281336424410
Pubmed

Histone demethylase KDM4C controls tumorigenesis of glioblastoma by epigenetically regulating p53 and c-Myc.

MYC KDM4C

8.02e-054128233462212
Pubmed

Dependence receptors: the trophic theory revisited.

NTRK3 INSR

8.02e-054128221139137
Pubmed

Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity.

MYC PRMT6

8.02e-054128231930333
Pubmed

Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability.

MYC HDAC7

8.02e-054128236163081
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ZNF609 UBAP2 CHAF1A BIRC6 YEATS2 ZNF106 NEO1 SEC16A NAV1 PDZD8 SLC27A4

8.84e-057331281134672954
Pubmed

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.

ZNF609 NCOR2 SEC16A

9.31e-0524128333722704
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ZNF609 PCDH11Y INSR ZDHHC14 ZSWIM1 CEP43 HNRNPC PCNX2 YEATS2 KMT2C NCOR2 EEPD1 NAV1 LRP5 PPP1R9B LRRC7

1.20e-0414891281628611215
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

MUC16 CCDC85A YEATS2 NCOR2 SALL1 GYS1 ITSN2 OTUD4 LTV1 HERC6

1.31e-046381281031182584
Pubmed

The developmental regulator protein Gon4l associates with protein YY1, co-repressor Sin3a, and histone deacetylase 1 and mediates transcriptional repression.

GON4L YY1AP1

1.33e-045128221454521
Pubmed

Nicotinamide Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-Derived Suppressor Cells.

SIRT1 CSF3R

1.33e-045128230777853
Pubmed

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression.

HDAC7 NCOR2

1.33e-045128210640276
Pubmed

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.

SIRT1 NCOR2

1.33e-045128215175761
Pubmed

Immunohistochemical distinction of renal cell carcinoma from other carcinomas with clear-cell histomorphology: utility of CD10 and CA-125 in addition to PAX-2, PAX-8, RCCma, and adipophilin.

MUC16 PAX8

2.00e-046128225279712
Pubmed

Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: Emergence of new molecular targets.

ERVV-2 ERVV-1

2.00e-046128223085571
Pubmed

CRM1 mediates nuclear export of HDAC7 independently of HDAC7 phosphorylation and association with 14-3-3s.

HDAC7 NCOR2

2.00e-046128216956611
Pubmed

Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1.

MYC NEO1

2.00e-046128233504783
Pubmed

Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice.

INSR GYS1 PGM2

2.68e-0434128323300479
Pubmed

CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation.

MAP4K2 STK25

2.79e-047128220332113
Pubmed

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta.

HDAC7 NCOR2

2.79e-047128212970571
Pubmed

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

MYC RIF1

2.79e-047128226308889
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PLK2 UBAP2 TRA2B TRPM7 NTRK3 HDAC7 LPIN3 FSIP2 ZNF106 SEC16A NAV1

3.54e-048611281136931259
Pubmed

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

MYC TIPARP

3.71e-048128220852632
Pubmed

Syncytins expressed in human placental trophoblast.

ERVV-2 ERVV-1

3.71e-048128233504453
Pubmed

Differential expression of HDAC and HAT genes in atrophying skeletal muscle.

HDAC7 SIRT1

3.71e-048128226372908
Pubmed

Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.

CHAF1A ZNF106 RPL3

3.74e-0438128328680062
Pubmed

A human MAP kinase interactome.

MYC CHAF1A KMT2C ZNF106 RIF1 ITSN2 NAV1 YY1AP1

4.55e-04486128820936779
Pubmed

A protein interaction network for pluripotency of embryonic stem cells.

ZNF609 RIF1 SALL1

4.69e-0441128317093407
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYC TRA2B DHX37 SRCAP BIRC6 HNRNPC NCOR2 RIF1 TPP1 SEC16A LTV1 KIF18B RPL3 SLC27A4

4.75e-0413531281429467282
Pubmed

Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.

HDAC7 NCOR2

4.76e-049128211466315
Pubmed

Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor.

MYC SALL1

4.76e-049128221423180
Pubmed

The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificities.

NTRK3 INSR

4.76e-049128212237455
Pubmed

A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.

SHANK3 LRRC7

4.76e-049128228130356
Pubmed

Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1.

SIRT1 NCOR2

4.76e-049128219244234
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SECISBP2L KDM4C BIRC6 SHANK3 CCDC85A FAT2 ZBTB39 EEPD1

4.99e-04493128815368895
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BIRC6 YEATS2 ITSN2 NAV1

5.84e-04103128410574462
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SDK2 UBAP2 DHX37 KMT2C

5.84e-04103128410819331
Pubmed

In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1.

SALL1 PAX8

5.93e-0410128221345181
Pubmed

Multiple tumor suppressor pathways negatively regulate telomerase.

MYC SIRT1

5.93e-0410128212837246
Pubmed

Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.

MYC ITSN2

5.93e-0410128225261932
Pubmed

Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.

PPP1R9B LRRC7

5.93e-0410128220124353
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZNF609 SRCAP ZBTB39 SEC16A

6.06e-0410412849205841
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

NTRK3 GRM1 CIT SHANK3 PPP1R9B LRRC7

6.28e-04281128628706196
InteractionSMG7 interactions

SECISBP2L ZNF609 SIRT1 PRMT6 YEATS2 NCOR2 ZNF106 SALL1 SEC16A OTUD4

1.36e-0531911410int:SMG7
InteractionMYO6 interactions

MYC TRA2B NTRK3 CIT HNRNPC TIPARP YEATS2 ITSN2 SEC16A PPP1R9B LTV1

1.62e-0539811411int:MYO6
InteractionFAM90A26 interactions

FAM90A1 FAM90A26

3.17e-0521142int:FAM90A26
InteractionAKAP9 interactions

FAM90A1 BIRC6 CIT CEP43 HNRNPC TIPARP GLIS2 STK25

3.74e-052211148int:AKAP9
InteractionPABPC1 interactions

MYC BRIX1 UBAP2 TRA2B CHAF1A BAG5 CIT HNRNPC TDRD7 PRMT6 KMT2C OTUD4 PDZD8 RPL3

4.07e-0569911414int:PABPC1
InteractionANKRD28 interactions

MYC PLK2 CHAF1A BAG5 SHANK3 SEC16A PDZD8 PPP1R9B

5.77e-052351148int:ANKRD28
InteractionFBL interactions

MYC BRIX1 UBAP2 DHX37 CIT TIPARP PRMT6 SEC16A OTUD4 YY1AP1 LTV1 RPL3 MAP4K2

6.67e-0563911413int:FBL
InteractionPPP1CC interactions

SECISBP2L MYC BRIX1 DEAF1 TRA2B CIT HNRNPC SHANK3 RIF1 GYS1 ITSN2 NAV1 PPP1R9B RPL3

7.29e-0573811414int:PPP1CC
InteractionNR0B1 interactions

MYC ZNF609 RIF1 SALL1

7.58e-05401144int:NR0B1
InteractionHBS1L interactions

MYC FAM90A1 CIT CCDC85A TIPARP STK25

7.79e-051251146int:HBS1L
InteractionMOS interactions

MYC BIRC6 CIT MTUS2 STK25

8.06e-05781145int:MOS
InteractionGOLGA1 interactions

BIRC6 CEP43 DMXL1 SEC16A NAV1 PPP1R9B LTV1

8.24e-051831147int:GOLGA1
InteractionDCLK1 interactions

MYC HDAC7 SHANK3 LPIN3 NAV1 PPP1R9B

8.51e-051271146int:DCLK1
InteractionCPSF1 interactions

MYC TRA2B CHAF1A CIT TIPARP YEATS2 SALL1 GLIS2

1.02e-042551148int:CPSF1
InteractionTFB1M interactions

MYC CIT TIPARP RPL3 MAP4K2

1.08e-04831145int:TFB1M
InteractionLGALS1 interactions

MYC SDK2 NTRK3 INSR CD109 MUC16 CIT NEO1 SUSD2

1.14e-043321149int:LGALS1
InteractionCDKN2A interactions

MYC DEAF1 CIT HNRNPC SLC4A1 TDRD7 NCOR2 GLIS2 PPP1R9B

1.22e-043351149int:CDKN2A
InteractionFXR1 interactions

MYC PLK2 UBAP2 DEAF1 FAM90A1 CIT SHANK3 TDRD7 NCOR2 SEC16A OTUD4 YY1AP1 MTUS2

1.22e-0467911413int:FXR1
InteractionRBM4B interactions

MYC BRIX1 DHX37 CIT HNRNPC LTV1 RPL3 MAP4K2

1.23e-042621148int:RBM4B
InteractionNCOR2 interactions

MYC BAG5 HDAC7 SIRT1 TIPARP NCOR2 PAX8 SEC16A

1.30e-042641148int:NCOR2
InteractionNUP50 interactions

MYC UBAP2 CIT SIRT1 TIPARP YEATS2 ITSN2 PDZD8 KIF18B

1.40e-043411149int:NUP50
InteractionRBBP7 interactions

MYC CHAF1A BAG5 BIRC6 CIT SIRT1 TIPARP ZNF750 NCOR2 SALL1 RPL3

1.43e-0450711411int:RBBP7
Cytoband8p23.1

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

7.32e-13154128118p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

6.87e-1123412811chr8p23
Cytoband9q21.32

SPATA31D4 SPATA31D1 SPATA31D3

1.99e-051912839q21.32
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp-Endothelial_Tip.Dcn.Mgp-Clu_(Clu)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PI16 CD109 ZNF750 FAT2 IFI44L PRG4

2.19e-079611869a1da3809073a4321134bf3767e0a40398b69caa
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDHHC14 SHANK3 CCDC85A EEPD1 IFI44L HERC6 LRRC36

5.92e-071831187e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MUC16 CSMD3 KMT2C CSF3R NAV1 PPP1R9B KDM7A

6.60e-07186118723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLK2 CHAF1A MUC16 FAM221B ADM5 FAT2 EEPD1

1.00e-06198118728ada093cec552262731194a04a4b9ff93186c3b
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANKLE1 ZSWIM1 SLC4A1 RIF1 LRRC7 KIF18B

3.01e-061501186c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANKLE1 ZSWIM1 SLC4A1 RIF1 LRRC7 KIF18B

3.01e-06150118678b8029e71d26f336a46274c8afef3435bf536b9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHAF1A CD109 ANKLE1 CIT RIF1 KIF18B

6.61e-0617211862b6cd84c946b1e800caba452ae70145ea285fec1
ToppCelldroplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKLE1 NXPE2 SLC4A1 KIF18B POLQ LRRC36

8.31e-061791186804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 ZDHHC14 SHANK3 CCDC85A EEPD1 LRRC36

1.10e-05188118673f6ec915934154f435a376cb274b058ff7c5f35
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 CD109 SHANK3 CCDC85A EEPD1 LRRC36

1.10e-051881186789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCellLPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 CD109 SHANK3 CCDC85A EEPD1 LRRC36

1.13e-051891186e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 ZDHHC14 CCDC85A EEPD1 PPP1R9B LRRC36

1.13e-0518911865d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHAF1A CD109 ANKRD36C NAV1 KIF18B POLQ

1.17e-05190118631de1727822e9818652946dfb962daee77ffad68
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 ZDHHC14 SHANK3 CCDC85A EEPD1 LRRC36

1.17e-051901186a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SHANK3 CCDC85A EEPD1 PPP1R9B LRRC36

1.17e-051901186106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 ZDHHC14 SHANK3 CCDC85A EEPD1 LRRC36

1.24e-051921186c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 CD109 ZDHHC14 SHANK3 CCDC85A LRRC36

1.27e-051931186e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 ZDHHC14 SHANK3 CCDC85A EEPD1 LRRC36

1.27e-051931186aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 ZDHHC14 SHANK3 CCDC85A EEPD1 LRRC36

1.27e-051931186c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLK2 ZDHHC14 SHANK3 CCDC85A NAV1 LRRC36

1.27e-051931186e1d546165dcc2392f540162206852c4717d7306f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 CD109 SHANK3 CCDC85A NAV1 IFI44L

1.27e-0519311866a623acd1adad9a78eddc32ffedb16352ad3fdfa
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

INSR CD109 SHANK3 CCDC85A EEPD1 IFI44L

1.31e-051941186a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 CD109 SHANK3 CCDC85A NAV1 IFI44L

1.35e-05195118677e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHAF1A CIT CEP43 CCDC85A KIF18B POLQ

1.52e-0519911861d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CD109 ZNF750 FAT2 IFI44L PRG4

2.00e-051241185b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CD109 ZNF750 FAT2 IFI44L PRG4

2.00e-051241185231862f849d8ab73c6a44c782d33ef2f07661baf
ToppCellMild/Remission-B_naive-5|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

LILRA6 ADM5 FCRL1 CSF3R ZNF543

3.83e-051421185fc5fc2d2b4b976358b8ce762c1f440b20db84103
ToppCellCOVID-19-lung-Mesothelial|lung / Disease (COVID-19 only), tissue and cell type

SPEG MUC16 KCNB1 PRG4 MTUS2

6.00e-051561185e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCellPND01-03-samps-Myeloid-Macrophage-CD163+_Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ZDHHC14 ZNF831 CIT C3AR1 KIF18B

6.76e-0516011854480a7d6bd48d06b4e5196faac868f31ab7ed3ad
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 CD109 CCDC85A ADM5 LRRC36

7.38e-0516311851feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI16 LILRA6 ZNF831 CSF3R KDM7A

7.82e-0516511854fe7c3c9370a556cf4e308a2e723b4b907a6cc25
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG CD109 SHANK3 ADM5 NAV1

8.75e-051691185c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DHX37 LILRA6 TDRD7 KCNB1

1.09e-041771185c2b8a3a149d70f77612759dea34df9e43953c566
ToppCell368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CHAF1A CD109 CIT KIF18B POLQ

1.09e-041771185844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DHX37 LILRA6 TDRD7 KCNB1

1.09e-041771185384f841aa7b2d05815af7885e481f5affc55d897
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 DHX37 LILRA6 TDRD7 KCNB1

1.09e-0417711850e9e44119653abfd270e602e5e477a15e774638f
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 HDAC7 SHANK3 EEPD1 POLQ

1.12e-041781185ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYC PI16 PIH1D2 TIPARP KIF18B

1.21e-041811185c26d3cbbc592299786d79d1b15fc6bead2aafb9a
ToppCellHealthy_Control-Lymphoid-T-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CCDC73 CHAF1A CIT KIF18B POLQ

1.21e-041811185ac1ee313910c05b1b3cb497bae14565464919c21
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYC PI16 NEO1 EEPD1 IFI44L

1.34e-041851185e34473eea3a58c041183a4f52137366cd9489495
ToppCellCOVID-cycling-|COVID / Condition, Cell_class and T cell subcluster

CIT SLC4A1 KCNB1 KIF18B POLQ

1.34e-041851185eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCellCOVID-cycling|COVID / Condition, Cell_class and T cell subcluster

CIT SLC4A1 KCNB1 KIF18B POLQ

1.34e-0418511855112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

INSR MUC16 NXPE2 ANKRD36C KCNB1

1.37e-041861185ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZDHHC14 SHANK3 CCDC85A EEPD1 LRRC36

1.41e-041871185ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 CD109 SHANK3 CCDC85A NAV1

1.52e-041901185bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellPND01-03-samps-Endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PLK2 HDAC7 SHANK3 CCDC85A NAV1

1.52e-0419011851357bd4527399d7013ee33272bda7453f472999a
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

PCDH11Y CD109 SHANK3 CCDC85A NAV1

1.52e-0419011851519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 ZDHHC14 CCDC85A EEPD1 LRRC36

1.52e-041901185474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PLK2 HDAC7 SHANK3 CCDC85A NAV1

1.52e-0419011855130fb325f80f591b9b36beacb8072c4472304f2
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PLK2 CD109 SHANK3 CCDC85A NAV1

1.52e-0419011858d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHAF1A CIT LRRC7 KIF18B POLQ

1.52e-041901185e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CHAF1A CIT CEP43 KIF18B POLQ

1.52e-041901185d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCDH11Y INSR CD109 SHANK3 NAV1

1.59e-04192118527ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

MYC ZNF609 IFI44L HERC6 RPL3

1.59e-04192118535557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCellLPS-IL1RA+antiTNF-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 ZDHHC14 SHANK3 CCDC85A LRRC36

1.59e-04192118504f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCellCOVID-19_Moderate-CD4+_T_activated|COVID-19_Moderate / disease group, cell group and cell class

MYC PI16 CCDC66 IFI44L HERC6

1.59e-0419211857a81652406332afd03a9b3b529e9b5e6c0b54c28
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 ZDHHC14 SHANK3 CCDC85A LRRC36

1.59e-041921185c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 SHANK3 CCDC85A NAV1 IFI44L

1.59e-04192118528eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYC CCDC66 IFI44L HERC6 RPL3

1.63e-0419311852901d7a9672a8cf70c9f1c752685b45e4d79ac70
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SHANK3 CCDC85A EEPD1 LRRC36

1.63e-04193118502f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 CD109 SHANK3 CCDC85A NAV1

1.63e-0419311852e72309607902dabe3218888b22a77fe941f3570
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD109 SHANK3 CCDC85A EEPD1 LRRC36

1.63e-0419311855122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLK2 INSR CD109 SHANK3 IFI44L

1.63e-041931185cc355b2ed6510619cad969ae074126d7c8db784d
ToppCellCOVID-19_Severe-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Severe / Disease group, lineage and cell class

MYC CCDC66 IFI44L HERC6 RPL3

1.63e-041931185beb862d38b88572836b0a797c8efef7a2492e0b9
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYC CCDC66 IFI44L HERC6 RPL3

1.63e-041931185f4310faa13fc8ce99a217e2d1c9cc733683797a1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 CD109 SHANK3 NAV1 IFI44L

1.63e-0419311850b328f725f6feba263783eaca60c142e80df90f3
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYC CCDC66 IFI44L HERC6 RPL3

1.63e-041931185f8af695457d2a0a911a5ac491742465864ebda37
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYC CCDC66 IFI44L HERC6 RPL3

1.63e-041931185089aece40130034a89a5213be778f10b0787eeba
ToppCellCOPD-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

INSR ADM5 KCNB1 OTUD4 LTV1

1.67e-0419411858dcde77767b23e75360adb316cdccf56a00e3726
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PI16 CD109 SHANK3 CCDC85A NAV1

1.67e-041941185b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PLK2 INSR CD109 SHANK3 NAV1

1.71e-041951185a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INSR CD109 SHANK3 CCDC85A NAV1

1.71e-0419511856bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

CCDC73 CIT SLC4A1 KIF18B POLQ

1.71e-041951185764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SECISBP2L DMXL1 TDRD7 IFI44L HERC6

1.71e-041951185b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LILRA6 NCOR2 ZNF106 CSF3R C3AR1

1.79e-0419711859838dbd1623babf8de7e9126a28fe5d3666bce42
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 SHANK3 CCDC85A NAV1 IFI44L

1.84e-041981185b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 SHANK3 CCDC85A NAV1 IFI44L

1.84e-041981185953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHAF1A CIT FAT2 KIF18B POLQ

1.84e-041981185f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CD109 SHANK3 CCDC85A NAV1 IFI44L

1.84e-0419811858e45551224fbb30c0658ad47dd98335ecf165437
ToppCellParenchymal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD109 ZDHHC14 SHANK3 EEPD1 NAV1

1.88e-041991185a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CD109 ZDHHC14 SHANK3 EEPD1 NAV1

1.88e-041991185d58edc5f74970bb26d844746184e4bae7c494d6b
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

INSR SHANK3 ADM5 MAP4K2 LRRC36

1.88e-0419911851295f34a350bf48987e2fad411aaac3630efd3f1
ToppCellTransverse-(2)_B_cell-(24)_B_cell_cycling|Transverse / shred on region, Cell_type, and subtype

CIT SIRT1 YEATS2 KIF18B POLQ

1.92e-042001185e3f9736227151f23f0e331eec0a7a15ce464b517
ToppCellTransverse-B_cell-B_cell_cycling|Transverse / Region, Cell class and subclass

CIT SIRT1 YEATS2 KIF18B POLQ

1.92e-0420011850e270f8019d9f22068ca426d661937262a5cd331
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TRA2B BIRC6 KMT2C ITSN2 IFI44L

1.92e-04200118512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SECISBP2L CIT CSF3R SUSD2 LRRC36

1.92e-042001185acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SECISBP2L CIT CSF3R SUSD2 LRRC36

1.92e-042001185ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

CHAF1A ANKRD36C CIT KIF18B POLQ

1.92e-042001185f277db6cc288a52a5426120c1067608700ee8ccc
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SECISBP2L CIT CSF3R SUSD2 LRRC36

1.92e-042001185eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Severe / Disease, condition lineage and cell class

MYC CCDC66 IFI44L HERC6 RPL3

1.92e-042001185deeed668b129e66156b5f6abe1a07a9bf842a14d
Diseasesalivary gland cancer (implicated_via_orthology)

GON4L YY1AP1

1.25e-0521052DOID:8850 (implicated_via_orthology)
DiseaseGastric Adenocarcinoma

TRPM7 SPEG NTRK3 INSR

2.02e-05451054C0278701
Diseasewhite matter hyperintensity measurement

GON4L ZNF831 CCDC85A NCOR2 ZNF106 KCNB1 SUSD2

1.06e-043021057EFO_0005665
Diseaseadenoid cystic carcinoma (is_implicated_in)

NTRK3 KMT2C

1.25e-0451052DOID:0080202 (is_implicated_in)
DiseaseTodd Paralysis

TRPM7 SIRT1

4.44e-0491052C0234544
DiseaseParalysed

TRPM7 SIRT1

4.44e-0491052C0522224
Diseasealopecia areata (is_marker_for)

KDM4C HDAC7

5.54e-04101052DOID:986 (is_marker_for)
Diseasetestosterone measurement

AOC1 CCDC73 INSR SRCAP CSMD3 BIRC6 HNRNPC PRMT6 NCOR2 GYS1 LRP5 YY1AP1 LRRC36

6.00e-04127510513EFO_0004908
DiseaseInfluenza

TDRD7 IFI44L HERC6

8.52e-04521053C0021400
Diseaseearly cardiac repolarization measurement

LRP5 PDZD8

1.11e-03141052EFO_0004885
Diseasequinate measurement

KDM4C EEPD1

1.28e-03151052EFO_0021167
Diseaseurate measurement, bone density

ZDHHC14 HNRNPC TIPARP FSIP2 SALL1 GLIS2 SEC16A NAV1

1.68e-036191058EFO_0003923, EFO_0004531
Diseasechemokine (C-C motif) ligand 27 measurement

UBAP2 KDM4C LRRC7

2.02e-03701053EFO_0008082
Diseaseosteoporosis (implicated_via_orthology)

MYC SIRT1

2.06e-03191052DOID:11476 (implicated_via_orthology)
Diseaseprostate adenocarcinoma (is_implicated_in)

MYC INSR

2.29e-03201052DOID:2526 (is_implicated_in)
Diseasepolymyositis

SDK2 LRP5

2.29e-03201052EFO_0003063
Diseaserespiratory symptom measurement, COVID-19

NTRK3 PRMT6 SALL1

2.36e-03741053EFO_0007939, MONDO_0100096
Diseaseprostate cancer (is_marker_for)

MYC KDM4C SIRT1 KMT2C

2.38e-031561054DOID:10283 (is_marker_for)
Diseasegoiter

INSR SALL1

3.02e-03231052EFO_0004283
Diseaseshort-term memory

PLK2 PRMT6 ITSN2

3.27e-03831053EFO_0004335
Diseasestomach carcinoma (is_marker_for)

KDM4C KMT2C

3.29e-03241052DOID:5517 (is_marker_for)
DiseaseLeukemia, Myelocytic, Acute

MYC NTRK3 KMT2C CSF3R

3.44e-031731054C0023467

Protein segments in the cluster

PeptideGeneStartEntry
TFPKSTHVPIPKSAD

PI16

306

Q6UXB8
PPTSKSTVEELHEPI

TWSG1

86

Q9GZX9
STPLTPATEPLHDFV

ARSF

516

P54793
LHISSPLTPAPETVF

ADM5

131

C9JUS6
PSLPVPLETVDKHGS

ANKLE1

191

Q8NAG6
KHPSLKPTTGVEDPA

ANKRD20A8P

331

Q5CZ79
KESPEIEPLPFTLAH

BIRC6

2311

Q9NR09
PSLPLSEDAHPSVAK

BAG5

171

Q9UL15
TGFHLPPPVTSTKSV

CSMD3

136

Q7Z407
HSPSGILEKIPPDSE

SLC4A1

211

P02730
TLLPHDPTADVFVTP

BRIX1

296

Q8TDN6
KNTSEEGFPSPTIHP

ERVV-2

136

B6SEH9
TEEPPLFSSHKPRGD

AOC1

276

P19801
LHTPTPSEDAAIPSK

CHAF1A

781

Q13111
SPKIPSGFPIEDHET

C3AR1

266

Q16581
PEEHYSSSPEKILSP

DMXL1

911

Q9Y485
EHITKRVASSPAPPE

CIT

1931

O14578
LTFTAKPHPSPTSLS

EEPD1

211

Q7L9B9
KPHPSPTSLSLQSED

EEPD1

216

Q7L9B9
SSLLAAPSFHSPEKP

FAM90A10

406

A6NDY2
GIPKPVFTHSKDTPS

MTUS2

596

Q5JR59
PHSPFAIKQETPEVS

PAX8

301

Q06710
PSPAEQKPAEHVSLS

OTUD4

556

Q01804
KLPTDPSSDEPVFHI

ITSN2

1501

Q9NZM3
TDLLHPVSSDVPTSP

TIPARP

161

Q7Z3E1
SSLLAAPSFHSPEKP

FAM90A7

406

A6NKC0
LDKASDPHLGTPSPE

MAP4K2

286

Q12851
VSPEQPPLFTHTVKD

ANKRD36C

511

Q5JPF3
SSLLAAPSFHSPEKP

FAM90A23

406

A8MXZ1
KTLVSSLHPEPPETG

FAM47C

336

Q5HY64
PPFTITHPVETSSAL

MUC16

2451

Q8WXI7
SKISTPDHDKSTVPP

MUC16

5231

Q8WXI7
EPVSPVSSPSLTHDK

NCOR2

2051

Q9Y618
LVGPPLHTPETEESK

LPIN3

316

Q9BQK8
SQPPEDHSPISRKEF

KCTD9

191

Q7L273
PVGETSFSVPLHPTK

KDM7A

881

Q6ZMT4
HKELFTKQPPSTPTS

KMT2C

1826

Q8NEZ4
HPSPSPLLSSSFDLD

HNRNPC

111

P07910
HLKEPSGPSELIPSS

LTV1

71

Q96GA3
TPPITVTHKPEEDTF

NTRK3

416

Q16288
EHIKESTEIPSPFSP

LRRC7

876

Q96NW7
SSLLTAPSFHSPEKP

FAM90A1

406

Q86YD7
RKPITPEHSTFITSP

IFI44L

296

Q53G44
PSSTSVFHLDPPVKK

KIAA2026

2031

Q5HYC2
EITKPPSDDSPAHSS

LRP5

1371

O75197
TSHPKPTAADNPELS

GPR50

526

Q13585
DVFQTTDVPLPKPSH

FSIP2

6156

Q5CZC0
KNTSEEGFPSPTIHP

ERVV-1

136

B6SEH8
SSLLAAPSFHSPEKP

FAM90A22

406

A8MWA6
SSLLAAPSFHSPEKP

FAM90A14

406

P0C7W9
LLEDHPIAPVSSTSP

PCNX2

176

A6NKB5
SPTEKFSLHPLTGEL

FAT2

861

Q9NYQ8
SSPEKELIPKPDTFH

LRRC36

286

Q1X8D7
LSEPGTDLVEPSPKH

PDZD8

956

Q8NEN9
HEKPFLSSSAPPITS

FAM214A

861

Q32MH5
KPSTSETPLEPHTSE

FAM221B

41

A6H8Z2
PSDTSKPTHPEALTE

HERC6

316

Q8IVU3
ITPTPFVPFTVSHLK

PGM2

141

Q96G03
YTIDHTKPTPASTPE

KDM4C

341

Q9H3R0
SSNPHLLSFPSEPLE

LILRA6

401

Q6PI73
TSVPTSPEEHRPFEK

INSR

786

P06213
SSLLAAPSFHSPEKP

FAM90A17

406

P0DV74
ALHLPASSFLTPPKD

GLIS2

141

Q9BZE0
SSLLAAPSFHSPEKP

FAM90A16

406

P0DV73
LSEEPPSKPSFHECI

KIF18B

726

Q86Y91
SSLLAAPSFHSPEKP

FAM90A19

406

P0DV76
SSLLAAPSFHSPEKP

FAM90A8

406

A6NJQ4
GPSSPSPVKFLIDTH

CD109

1211

Q6YHK3
HFESSPLPTSPKFLR

KCNB1

796

Q14721
LSDVHSPPKSPEGKT

CEP43

151

O95684
PKSPEKHDLNSTETP

GFY

211

I3L273
FPEAALPTSHPKIVL

DEAF1

406

O75398
PAELFLIASPSHPTE

FCRL1

16

Q96LA6
TLHTKPEPLEGPALS

FNDC11

301

Q9BVV2
TPESPIFHSPILLEE

POLQ

1411

O75417
FPTEHVKTKPLISTP

CCDC73

1006

Q6ZRK6
PLSATVFPKVEHSPG

GON4L

1256

Q3T8J9
IHSFSKERSPSSPVP

CCDC66

786

A2RUB6
SEKPLVLSTSPFHPA

PRMT6

301

Q96LA8
SPETLPKHVLSGSPE

CCDC85A

301

Q96PX6
PGPETHLPTSFTLKS

CSF3R

146

Q99062
FETPLSHLRQEPPKT

FAM47A

306

Q5JRC9
KTGVSHLSPEPPKTE

FAM47A

381

Q5JRC9
PPLPSDTFALAHTAT

KLHDC7A

616

Q5VTJ3
SSLLAAPSFHSPEKP

FAM90A20P

406

A6NIJ5
PSDPPEHFPLRKTVS

HDAC7

141

Q8WUI4
IFHPEFLSSTSPLLP

GYS1

476

P13807
ATTPPLPSHLTAEET

GRM1

986

Q13255
KTPLLDDPVFIHPSS

DHX37

956

Q8IY37
SSLLAAPSFHSPEKP

FAM90A5P

406

A8MXJ8
PDEAPTILSVTPHTT

SDK2

1501

Q58EX2
KTEEPAPIPISHSAT

SALL1

571

Q9NSC2
SSLLAAPSFHSPEKP

FAM90A24P

406

P0C7X0
TPTTFKPDSPDLARH

PCDH11Y

956

Q9BZA8
FEAKPPLSTAHPLTP

PCARE

1131

A6NGG8
PHSIASPPEDRTVKD

NAV1

1821

Q8NEY1
KHDPTFEPLFPSETT

SUSD2

656

Q9UGT4
HSETPLCPAVSPKET

NXPE2

66

Q96DL1
SFPKDDPSKPVHLTA

RPL3

31

P39023
SLEPLEHPLISSPSF

RIF1

456

Q5UIP0
EPLVLHEETPPTTSS

MYC

236

P01106
SSLLAAPSFHSPEKP

FAM90A12P

406

A8MX19
SSLLAAPSFHSPEKP

FAM90A9

406

A6NNJ1
SSLLAAPSFHSPEKP

FAM90A13P

406

P0C7W8
SSLLAAPSFHSPEKP

FAM90A26

406

D6RGX4
HGTTFELVPTSPPKD

NEO1

946

Q92859
ELPPTPLHVSEDSSS

SIRT1

526

Q96EB6
HSTSEKPSKLPFDTP

SECISBP2L

901

Q93073
QPVSPLDSKFPIDHS

SPATA31D4

221

Q6ZUB0
FSTEELPPPVHLSKP

TDRD7

896

Q8NHU6
KLVHSPSPEVSASAP

SRCAP

1376

Q6ZRS2
SSLLAAPSFHSPEKP

FAM90A15P

406

P0C7V4
PTTIHKSPDESTPEL

PRG4

866

Q92954
SPPTLEGQHSKPFKE

STK25

231

O00506
SPFLPPEFPHKISST

ZNF750

211

Q32MQ0
STTHPVPLTVGKPED

PIH1D2

81

Q8WWB5
TDLDHILPSSVLPPF

TMTC4

6

Q5T4D3
QPVSPLDSKFPIDHS

SPATA31D3

221

P0C874
SHLDFKSQPEPSPVL

UBAP2

421

Q5T6F2
SSRPTSPEKFSVPHV

SEC16A

1436

O15027
TLPSTHVTPSEPKPF

SPEG

2861

Q15772
HVTPSEPKPFVLDTG

SPEG

2866

Q15772
STFIHPLTGKPLDPS

SHANK3

1091

Q9BYB0
VPPSTEHLDPLLKDA

SLC27A4

211

Q6P1M0
VSPLDSKFPIDHSPP

SPATA31D1

226

Q6ZQQ2
LVEPHSPSPSSKFST

ZNF609

571

O15014
EPSLTSDELHLPGKP

ZDHHC14

381

Q8IZN3
PPKTEDHDTPAPFTS

ZBTB39

206

O15060
SPLSATVFPKVEHSP

YY1AP1

711

Q9H869
PKTTEPTFSHLALPE

ZNF543

86

Q08ER8
PSKHRTDEELQPPTT

PLK2

411

Q9NYY3
PPALEASLVTEPTKH

ZNF831

696

Q5JPB2
HAPSDTIPESPKLEQ

ZSWIM1

306

Q9BR11
VDFSITKRPHTPTPG

TRA2B

191

P62995
FASETPLEKEPHSPA

ZNF106

1316

Q9H2Y7
IPHLSSPPTKFFVST

TRPM7

1391

Q96QT4
SSPIKQSHEPVPDTS

YEATS2

366

Q9ULM3
VTKFLSSSPHLPPSS

TPP1

426

O14773
SSLLAAPSFHSPEKP

FAM90A18

406

P0DV75
EDPAPSRKIHFSTAP

PPP1R9B

441

Q96SB3