| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | glycerol channel activity | 1.79e-08 | 7 | 17 | 3 | GO:0015254 | |
| GeneOntologyMolecularFunction | glycerol transmembrane transporter activity | 4.29e-08 | 9 | 17 | 3 | GO:0015168 | |
| GeneOntologyMolecularFunction | urea transmembrane transporter activity | 4.29e-08 | 9 | 17 | 3 | GO:0015204 | |
| GeneOntologyMolecularFunction | polyol transmembrane transporter activity | 1.46e-07 | 13 | 17 | 3 | GO:0015166 | |
| GeneOntologyMolecularFunction | water channel activity | 3.46e-07 | 17 | 17 | 3 | GO:0015250 | |
| GeneOntologyMolecularFunction | water transmembrane transporter activity | 5.79e-07 | 20 | 17 | 3 | GO:0005372 | |
| GeneOntologyMolecularFunction | carbohydrate transmembrane transporter activity | 5.76e-06 | 42 | 17 | 3 | GO:0015144 | |
| GeneOntologyMolecularFunction | amide transmembrane transporter activity | 5.76e-06 | 42 | 17 | 3 | GO:0042887 | |
| GeneOntologyMolecularFunction | cupric ion binding | 6.81e-06 | 5 | 17 | 2 | GO:1903135 | |
| GeneOntologyMolecularFunction | organic hydroxy compound transmembrane transporter activity | 2.71e-05 | 70 | 17 | 3 | GO:1901618 | |
| GeneOntologyMolecularFunction | copper ion binding | 1.97e-03 | 78 | 17 | 2 | GO:0005507 | |
| GeneOntologyMolecularFunction | channel activity | 9.34e-03 | 525 | 17 | 3 | GO:0015267 | |
| GeneOntologyMolecularFunction | passive transmembrane transporter activity | 9.39e-03 | 526 | 17 | 3 | GO:0022803 | |
| GeneOntologyMolecularFunction | metallopeptidase activity | 1.23e-02 | 200 | 17 | 2 | GO:0008237 | |
| GeneOntologyMolecularFunction | peptidase activity | 1.69e-02 | 654 | 17 | 3 | GO:0008233 | |
| GeneOntologyBiologicalProcess | glycerol transmembrane transport | 3.89e-08 | 9 | 17 | 3 | GO:0015793 | |
| GeneOntologyBiologicalProcess | polyol transmembrane transport | 1.02e-07 | 12 | 17 | 3 | GO:0015791 | |
| GeneOntologyBiologicalProcess | urea transmembrane transport | 1.02e-07 | 12 | 17 | 3 | GO:0071918 | |
| GeneOntologyBiologicalProcess | urea transport | 1.68e-07 | 14 | 17 | 3 | GO:0015840 | |
| GeneOntologyBiologicalProcess | water transport | 2.27e-06 | 32 | 17 | 3 | GO:0006833 | |
| GeneOntologyBiologicalProcess | one-carbon compound transport | 2.50e-06 | 33 | 17 | 3 | GO:0019755 | |
| GeneOntologyBiologicalProcess | fluid transport | 5.23e-06 | 42 | 17 | 3 | GO:0042044 | |
| GeneOntologyBiologicalProcess | renal water absorption | 2.87e-05 | 10 | 17 | 2 | GO:0070295 | |
| GeneOntologyBiologicalProcess | membrane lipid metabolic process | 3.14e-05 | 229 | 17 | 4 | GO:0006643 | |
| GeneOntologyBiologicalProcess | renal water transport | 4.96e-05 | 13 | 17 | 2 | GO:0003097 | |
| GeneOntologyBiologicalProcess | glycoside metabolic process | 1.46e-04 | 22 | 17 | 2 | GO:0016137 | |
| GeneOntologyBiologicalProcess | renal water homeostasis | 2.05e-04 | 26 | 17 | 2 | GO:0003091 | |
| GeneOntologyBiologicalProcess | glycolipid catabolic process | 2.22e-04 | 27 | 17 | 2 | GO:0019377 | |
| GeneOntologyBiologicalProcess | carbohydrate transmembrane transport | 3.32e-04 | 168 | 17 | 3 | GO:0034219 | |
| GeneOntologyBiologicalProcess | multicellular organismal-level water homeostasis | 3.74e-04 | 35 | 17 | 2 | GO:0050891 | |
| GeneOntologyBiologicalProcess | sphingolipid metabolic process | 3.80e-04 | 176 | 17 | 3 | GO:0006665 | |
| GeneOntologyBiologicalProcess | carbohydrate transport | 4.47e-04 | 186 | 17 | 3 | GO:0008643 | |
| GeneOntologyBiologicalProcess | renal absorption | 6.20e-04 | 45 | 17 | 2 | GO:0070293 | |
| GeneOntologyBiologicalProcess | membrane lipid catabolic process | 9.25e-04 | 55 | 17 | 2 | GO:0046466 | |
| Domain | MIP | 6.22e-05 | 14 | 16 | 2 | PF00230 | |
| Domain | MIP | 6.22e-05 | 14 | 16 | 2 | PS00221 | |
| Domain | - | 7.18e-05 | 15 | 16 | 2 | 1.20.1080.10 | |
| Domain | Aquaporin-like | 7.18e-05 | 15 | 16 | 2 | IPR023271 | |
| Domain | MIP | 7.18e-05 | 15 | 16 | 2 | IPR000425 | |
| Domain | CTDL_fold | 3.70e-03 | 107 | 16 | 2 | IPR016187 | |
| Pathway | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | 5.15e-05 | 13 | 12 | 2 | MM15095 | |
| Pathway | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | 5.15e-05 | 13 | 12 | 2 | M911 | |
| Pathway | REACTOME_AQUAPORIN_MEDIATED_TRANSPORT | 5.09e-04 | 40 | 12 | 2 | MM15115 | |
| Pathway | REACTOME_AQUAPORIN_MEDIATED_TRANSPORT | 8.60e-04 | 52 | 12 | 2 | M920 | |
| Pubmed | Expression and clinical significance of aquaglyceroporins in human hepatocellular carcinoma. | 6.74e-07 | 3 | 17 | 2 | 27121567 | |
| Pubmed | Channel-dependent permeation of water and glycerol in mouse morulae. | 6.74e-07 | 3 | 17 | 2 | 16339044 | |
| Pubmed | 1.35e-06 | 4 | 17 | 2 | 26313002 | ||
| Pubmed | Human adipose glycerol flux is regulated by a pH gate in AQP10. | 1.35e-06 | 4 | 17 | 2 | 30420639 | |
| Pubmed | Aquaglyceroporins and orthodox aquaporins in human adipocytes. | 1.35e-06 | 4 | 17 | 2 | 34627746 | |
| Pubmed | Expression and localisation of aquaporin water channels in human urothelium in situ and in vitro. | 1.35e-06 | 4 | 17 | 2 | 18718702 | |
| Pubmed | 1.35e-06 | 4 | 17 | 2 | 28042826 | ||
| Pubmed | More than just water channels: unexpected cellular roles of aquaporins. | 2.25e-06 | 5 | 17 | 2 | 16079275 | |
| Pubmed | Lessons on renal physiology from transgenic mice lacking aquaporin water channels. | 4.72e-06 | 7 | 17 | 2 | 10232700 | |
| Pubmed | Aquaporin molecular biology and clinical abnormalities of the water transport channels. | 8.08e-06 | 9 | 17 | 2 | 9757370 | |
| Pubmed | mRNAs encoding aquaporins are present during murine preimplantation development. | 1.01e-05 | 10 | 17 | 2 | 11066060 | |
| Pubmed | Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia. | 1.01e-05 | 10 | 17 | 2 | 10318966 | |
| Pubmed | Expression of mRNAs of the aquaporin family in mouse oocytes and embryos. | 1.01e-05 | 10 | 17 | 2 | 10788316 | |
| Pubmed | 1.01e-05 | 10 | 17 | 2 | 12031518 | ||
| Pubmed | Functional characterization of human aquaporin 9 as a facilitative glycerol carrier. | 1.23e-05 | 11 | 17 | 2 | 18762715 | |
| Pubmed | Purification and functional characterization of aquaporin-8. | 1.23e-05 | 11 | 17 | 2 | 15948717 | |
| Pubmed | Functional and molecular characterization of the human neutral solute channel aquaporin-9. | 1.23e-05 | 11 | 17 | 2 | 10564231 | |
| Pubmed | 1.23e-05 | 11 | 17 | 2 | 7530250 | ||
| Pubmed | Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. | 1.23e-05 | 11 | 17 | 2 | 1373524 | |
| Pubmed | Identification of arylsulfonamides as Aquaporin 4 inhibitors. | 1.23e-05 | 11 | 17 | 2 | 17178220 | |
| Pubmed | 1.23e-05 | 11 | 17 | 2 | 18501347 | ||
| Pubmed | Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0-5. | 1.23e-05 | 11 | 17 | 2 | 9829975 | |
| Pubmed | Cloning and functional expression of human aquaporin8 cDNA and analysis of its gene. | 1.23e-05 | 11 | 17 | 2 | 9806845 | |
| Pubmed | 1.23e-05 | 11 | 17 | 2 | 21251984 | ||
| Pubmed | Roles of aquaporin-3 water channels in volume-regulatory water flow in a human epithelial cell line. | 1.23e-05 | 11 | 17 | 2 | 16596446 | |
| Pubmed | Structural determinants of water permeation through aquaporin-1. | 1.23e-05 | 11 | 17 | 2 | 11034202 | |
| Pubmed | 1.23e-05 | 11 | 17 | 2 | 11076974 | ||
| Pubmed | Novel variants in human Aquaporin-4 reduce cellular water permeability. | 1.23e-05 | 11 | 17 | 2 | 18511455 | |
| Pubmed | Functional characterization and localization of AQP3 in the human colon. | 1.23e-05 | 11 | 17 | 2 | 10510269 | |
| Pubmed | 1.23e-05 | 11 | 17 | 2 | 1510932 | ||
| Pubmed | Cloning of a new aquaporin (AQP10) abundantly expressed in duodenum and jejunum. | 1.23e-05 | 11 | 17 | 2 | 11573934 | |
| Pubmed | Cloning and identification of a new member of water channel (AQP10) as an aquaglyceroporin. | 1.23e-05 | 11 | 17 | 2 | 12084581 | |
| Pubmed | Functional impairment of lens aquaporin in two families with dominantly inherited cataracts. | 1.23e-05 | 11 | 17 | 2 | 11001937 | |
| Pubmed | 1.23e-05 | 11 | 17 | 2 | 14701836 | ||
| Pubmed | Mercury-sensitive residues and pore site in AQP3 water channel. | 1.23e-05 | 11 | 17 | 2 | 9369468 | |
| Pubmed | 1.23e-05 | 11 | 17 | 2 | 9405233 | ||
| Pubmed | Mechanism of selectivity in aquaporins and aquaglyceroporins. | 1.23e-05 | 11 | 17 | 2 | 18202181 | |
| Pubmed | Aquaporins 8 and 9 as Possible Markers for Adult Murine Lacrimal Gland Cells. | 2.35e-05 | 15 | 17 | 2 | 34540996 | |
| Pubmed | 3.05e-05 | 17 | 17 | 2 | 26847765 | ||
| Pubmed | 3.83e-05 | 19 | 17 | 2 | 19367412 | ||
| Pubmed | Leukodystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY | 3.29e-04 | 55 | 17 | 2 | 24501781 | |
| Cytoband | 9p13 | 3.25e-05 | 23 | 17 | 2 | 9p13 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr9p13 | 1.87e-03 | 174 | 17 | 2 | chr9p13 | |
| GeneFamily | Aquaporins | 3.05e-05 | 14 | 11 | 2 | 305 | |
| Computational | Liver genes - metabolism and xenobiotics. | 4.40e-04 | 563 | 8 | 4 | MODULE_23 | |
| Drug | Urea | 1.03e-06 | 29 | 16 | 3 | ctd:D014508 | |
| Disease | glycerol measurement | 8.89e-05 | 26 | 16 | 2 | EFO_0010115 | |
| Disease | chemokine (C-C motif) ligand 27 measurement | 6.52e-04 | 70 | 16 | 2 | EFO_0008082 | |
| Disease | non-small cell lung carcinoma | 7.48e-04 | 75 | 16 | 2 | EFO_0003060 | |
| Disease | type 2 diabetes mellitus (is_marker_for) | 2.43e-03 | 136 | 16 | 2 | DOID:9352 (is_marker_for) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| TSGRWWLGAASWWWL | 21 | F7VJQ1 | |
| WLGAASWWWLGAASW | 26 | F7VJQ1 | |
| RFSWNGSWSDEWPHW | 741 | O75808 | |
| GWGKQVFSDGENWWW | 246 | A0A075B734 | |
| WIFAQGWGWAGHWDS | 16 | Q0VG99 | |
| VFSVPAWGSEWFWWH | 66 | P04066 | |
| AWGSEWFWWHWQGEG | 71 | P04066 | |
| TAFWWGEWTKWTACS | 46 | Q86TH1 | |
| GWGKQVFSNGENWWW | 241 | O14520 | |
| HSWVGAWRGPQGWHW | 346 | A4D1S0 | |
| NGIVWYTWHGWWYSL | 281 | Q08830 | |
| HVFHHSVLPWSWWWG | 141 | Q9BW60 | |
| EWWTHLWLNEGFASW | 366 | P55786 | |
| SLQWEVGGWRWWGLS | 31 | Q96GQ5 | |
| GNAWEWTSDWWTVHH | 296 | Q8NBK3 | |
| WGSAVFTTGQHWWWV | 231 | Q92482 | |
| MWWVCFWHWDGLVSS | 211 | Q9UBY8 | |
| ATQGWLNWEGTWKWF | 466 | P60508 | |
| WGSWHEHVKGWWEAK | 176 | O75897 |