Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	FZD4 ADGRG3 ADRB2 HTR2C GPR61 OR1B1 OR4Q2 ACKR3 FPR3 OR5H8 NPSR1 GPR37L1 HRH4 ADGRD2 TACR1 OR2Z1 NMBR CHRM3 GABBR1 OR8G1	7.41e-12	884	68	20	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	FZD4 ADGRG3 ADRB2 HTR2C GPR61 OR1B1 LMBR1L OR4Q2 ACKR3 FPR3 OR5H8 NPSR1 GPR37L1 HRH4 ADGRD2 TACR1 OR2Z1 NMBR CHRM3 GABBR1 CD160 OR8G1	3.16e-10	1353	68	22	GO:0004888
GeneOntologyMolecularFunction	G protein-coupled neurotransmitter receptor activity	HRH4 CHRM3 GABBR1	1.05e-05	13	68	3	GO:0099528
GeneOntologyMolecularFunction	G protein-coupled amine receptor activity	ADRB2 HTR2C HRH4 CHRM3	1.13e-05	41	68	4	GO:0008227
GeneOntologyMolecularFunction	G protein-coupled serotonin receptor activity	HTR2C HRH4 CHRM3	5.55e-05	22	68	3	GO:0004993
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	FPR3 NPSR1 GPR37L1 TACR1 NMBR	9.05e-05	133	68	5	GO:0008528
GeneOntologyMolecularFunction	peptide receptor activity	FPR3 NPSR1 GPR37L1 TACR1 NMBR	1.15e-04	140	68	5	GO:0001653
GeneOntologyMolecularFunction	phosphatidylethanolamine flippase activity	ATP11B ATP8A2	2.37e-04	7	68	2	GO:0090555
GeneOntologyMolecularFunction	G protein-coupled acetylcholine receptor activity	HRH4 CHRM3	2.37e-04	7	68	2	GO:0016907
GeneOntologyMolecularFunction	neurotransmitter receptor activity	HTR2C HRH4 CHRM3 GABBR1	3.77e-04	100	68	4	GO:0030594
GeneOntologyMolecularFunction	phosphatidylserine floppase activity	ATP11B ATP8A2	4.05e-04	9	68	2	GO:0090556
GeneOntologyMolecularFunction	TAP complex binding	HLA-A HLA-H	4.05e-04	9	68	2	GO:0062061
GeneOntologyMolecularFunction	CD8 receptor binding	HLA-A HLA-H	4.05e-04	9	68	2	GO:0042610
GeneOntologyMolecularFunction	TAP1 binding	HLA-A HLA-H	5.05e-04	10	68	2	GO:0046978
GeneOntologyMolecularFunction	TAP2 binding	HLA-A HLA-H	5.05e-04	10	68	2	GO:0046979
GeneOntologyMolecularFunction	TAP binding	HLA-A HLA-H	5.05e-04	10	68	2	GO:0046977
GeneOntologyMolecularFunction	beta-2-microglobulin binding	HLA-A HLA-H	7.38e-04	12	68	2	GO:0030881
GeneOntologyMolecularFunction	peptide binding	FZD4 ADRB2 HLA-A FPR3 HLA-H GPR37L1	7.43e-04	318	68	6	GO:0042277
GeneOntologyMolecularFunction	neuropeptide receptor activity	NPSR1 TACR1 NMBR	7.83e-04	53	68	3	GO:0008188
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ATP11B ATP8A2	1.01e-03	14	68	2	GO:0140333
GeneOntologyMolecularFunction	transporter activity	ABCC4 ATP7B ATP11B ATP8A2 SLC6A17 GJB6 KCNK10 SLC45A2 OTOP3 TMEM87A SLC6A14 TPCN1	1.25e-03	1289	68	12	GO:0005215
GeneOntologyMolecularFunction	floppase activity	ATP11B ATP8A2	1.33e-03	16	68	2	GO:0140328
GeneOntologyMolecularFunction	natural killer cell lectin-like receptor binding	HLA-A HLA-H	1.50e-03	17	68	2	GO:0046703
GeneOntologyMolecularFunction	flippase activity	ATP11B ATP8A2	1.50e-03	17	68	2	GO:0140327
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCC4 ATP7B ATP11B SLC6A17 GJB6 KCNK10 SLC45A2 OTOP3 TMEM87A SLC6A14 TPCN1	2.01e-03	1180	68	11	GO:0022857
GeneOntologyMolecularFunction	T cell receptor binding	HLA-A HLA-H	2.09e-03	20	68	2	GO:0042608
GeneOntologyMolecularFunction	postsynaptic neurotransmitter receptor activity	HRH4 CHRM3 GABBR1	2.14e-03	75	68	3	GO:0098960
GeneOntologyMolecularFunction	immune receptor activity	FZD4 ACKR3 FPR3 CD160	2.43e-03	165	68	4	GO:0140375
GeneOntologyMolecularFunction	acetylcholine receptor activity	HRH4 CHRM3	2.76e-03	23	68	2	GO:0015464
GeneOntologyMolecularFunction	syntaxin binding	VAMP8 VAMP3 TPCN1	3.26e-03	87	68	3	GO:0019905
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	GDPD5 CHRM3	3.52e-03	26	68	2	GO:0004435
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP11B ATP8A2	4.08e-03	28	68	2	GO:0140326
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	ABCC4 ATP7B KCNK10 SLC45A2 OTOP3 TMEM87A SLC6A14 TPCN1	4.12e-03	758	68	8	GO:0015318
GeneOntologyMolecularFunction	phospholipase C activity	GDPD5 CHRM3	4.37e-03	29	68	2	GO:0004629
GeneOntologyMolecularFunction	amyloid-beta binding	FZD4 ADRB2 FPR3	5.10e-03	102	68	3	GO:0001540
GeneOntologyMolecularFunction	MHC class I protein binding	HLA-A HLA-H	5.31e-03	32	68	2	GO:0042288
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	ATP7B KCNK10 SLC45A2 OTOP3 TMEM87A SLC6A14 TPCN1	5.38e-03	627	68	7	GO:0022890
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	ATP7B ATP11B KCNK10 SLC45A2 OTOP3 TMEM87A SLC6A14 TPCN1	5.39e-03	793	68	8	GO:0015075
GeneOntologyMolecularFunction	modified amino acid transmembrane transporter activity	ABCC4 SLC6A14	5.64e-03	33	68	2	GO:0072349
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	ATP7B KCNK10 SLC45A2 OTOP3 TMEM87A SLC6A14 TPCN1	7.30e-03	664	68	7	GO:0008324
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	FZD4 ADGRG3 ADRB2 HTR2C GPR61 OR1B1 OR4Q2 ACKR3 FPR3 OR5H8 NPSR1 GPR37L1 HRH4 ADGRD2 TACR1 OR2Z1 NMBR CHRM3 GABBR1 OR8G1	1.25e-08	1395	68	20	GO:0007186
GeneOntologyBiologicalProcess	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	ADGRG3 ADRB2 GPR61 GPR37L1 HRH4 ADGRD2 CHRM3 GABBR1	4.46e-06	286	68	8	GO:0007188
GeneOntologyBiologicalProcess	G protein-coupled serotonin receptor signaling pathway	HTR2C HRH4 CHRM3	5.79e-05	23	68	3	GO:0098664
GeneOntologyBiologicalProcess	involuntary skeletal muscle contraction	ADRB2 ATP8A2	6.40e-05	4	68	2	GO:0003011
GeneOntologyBiologicalProcess	hormone secretion	FZD4 HTR2C TACR1 G6PC2 VAMP8 CHRM3 GABBR1 VAMP3	7.02e-05	420	68	8	GO:0046879
GeneOntologyBiologicalProcess	phospholipase C-activating G protein-coupled receptor signaling pathway	HTR2C FPR3 TACR1 NMBR CHRM3	7.78e-05	133	68	5	GO:0007200
GeneOntologyBiologicalProcess	hormone transport	FZD4 HTR2C TACR1 G6PC2 VAMP8 CHRM3 GABBR1 VAMP3	8.55e-05	432	68	8	GO:0009914
GeneOntologyBiologicalProcess	secretion	FZD4 ABCC4 ATP7B HTR2C NPSR1 TACR1 TVP23B G6PC2 VAMP8 CHRM3 GABBR1 CD160 VAMP3	1.53e-04	1221	68	13	GO:0046903
GeneOntologyBiologicalProcess	regulation of hormone secretion	HTR2C TACR1 G6PC2 VAMP8 CHRM3 GABBR1 VAMP3	1.66e-04	355	68	7	GO:0046883
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	GPR37L1 HRH4 CHRM3 GABBR1	1.87e-04	86	68	4	GO:0007193
GeneOntologyBiologicalProcess	signal release	FZD4 ABCC4 HTR2C TACR1 G6PC2 VAMP8 CHRM3 GABBR1 VAMP3	2.81e-04	653	68	9	GO:0023061
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	HRH4 CHRM3	2.96e-04	8	68	2	GO:0007197
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	HLA-A HLA-H	2.96e-04	8	68	2	GO:0002485
GeneOntologyBiologicalProcess	regulation of histamine secretion by mast cell	VAMP8 VAMP3	2.96e-04	8	68	2	GO:1903593
GeneOntologyBiologicalProcess	export from cell	FZD4 ABCC4 ATP7B HTR2C TACR1 TVP23B G6PC2 VAMP8 CHRM3 GABBR1 CD160 VAMP3	3.50e-04	1153	68	12	GO:0140352
GeneOntologyBiologicalProcess	aminophospholipid transport	ATP11B ATP8A2	3.80e-04	9	68	2	GO:0015917
GeneOntologyBiologicalProcess	synaptic transmission, cholinergic	HTR2C TACR1 CHRM3	4.12e-04	44	68	3	GO:0007271
GeneOntologyBiologicalProcess	retrograde transport, endosome to Golgi	TMEM87B GOLT1A TMEM87A VAMP3	4.63e-04	109	68	4	GO:0042147
GeneOntologyCellularComponent	recycling endosome membrane	ATP11B HLA-A HLA-H VAMP8 VAMP3 TPCN1	1.73e-06	112	68	6	GO:0055038
GeneOntologyCellularComponent	recycling endosome	ATP11B HLA-A ACKR3 HLA-H VAMP8 VAMP3 TPCN1	7.75e-06	222	68	7	GO:0055037
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	FZD4 TARM1 ABCC4 ADGRG3 ADRB2 ATP11B GPR61 HLA-A ATP8A2 SLC6A17 HLA-H SLC45A2 VAMP8 VAMP3 TPCN1	1.54e-05	1307	68	15	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	FZD4 TARM1 ABCC4 ADGRG3 ADRB2 ATP11B GPR61 HLA-A ATP8A2 SLC6A17 HLA-H SLC45A2 VAMP8 VAMP3 TPCN1	1.81e-05	1325	68	15	GO:0012506
GeneOntologyCellularComponent	early endosome membrane	ATP11B HLA-A HLA-H VAMP8 VAMP3 TPCN1	6.57e-05	212	68	6	GO:0031901
GeneOntologyCellularComponent	endocytic vesicle membrane	FZD4 ADRB2 HLA-A HLA-H VAMP8 VAMP3	6.57e-05	212	68	6	GO:0030666
GeneOntologyCellularComponent	coated vesicle membrane	FZD4 ADRB2 HLA-A HLA-H VAMP8 VAMP3	7.10e-05	215	68	6	GO:0030662
GeneOntologyCellularComponent	apical part of cell	LGMN ABCC4 ADRB2 ATP7B GJB6 PKHD1 MARVELD2 SLC6A14 VAMP3	1.23e-04	592	68	9	GO:0045177
GeneOntologyCellularComponent	clathrin-coated endocytic vesicle membrane	FZD4 ADRB2 VAMP8 VAMP3	1.28e-04	79	68	4	GO:0030669
GeneOntologyCellularComponent	endosome membrane	ADRB2 ATP11B GPR61 HLA-A ATP8A2 HLA-H VAMP8 VAMP3 TPCN1	1.39e-04	602	68	9	GO:0010008
GeneOntologyCellularComponent	phagocytic vesicle membrane	HLA-A HLA-H VAMP8 VAMP3	1.55e-04	83	68	4	GO:0030670
GeneOntologyCellularComponent	early endosome	ADRB2 ATP11B HLA-A ACKR3 HLA-H VAMP8 VAMP3 TPCN1	1.63e-04	481	68	8	GO:0005769
GeneOntologyCellularComponent	MHC class Ib protein complex	HLA-A HLA-H	2.17e-04	7	68	2	GO:0032398
GeneOntologyCellularComponent	clathrin-coated endocytic vesicle	FZD4 ADRB2 VAMP8 VAMP3	3.30e-04	101	68	4	GO:0045334
GeneOntologyCellularComponent	endosome	LGMN ADRB2 ATP7B ATP11B GPR61 HLA-A ACKR3 ATP8A2 HLA-H VAMP8 VAMP3 TPCN1	3.46e-04	1167	68	12	GO:0005768
GeneOntologyCellularComponent	MHC class I protein complex	HLA-A HLA-H	4.61e-04	10	68	2	GO:0042612
GeneOntologyCellularComponent	secretory granule membrane	TARM1 ABCC4 ADGRG3 ATP11B HLA-H VAMP8	7.00e-04	329	68	6	GO:0030667
GeneOntologyCellularComponent	cell surface	FZD4 ABCC4 HTR2C HLA-A ACKR3 BTN1A1 HLA-H PKHD1 TACR1 VAMP8 VAMP3	8.58e-04	1111	68	11	GO:0009986
GeneOntologyCellularComponent	MHC class I peptide loading complex	HLA-A HLA-H	9.25e-04	14	68	2	GO:0042824
GeneOntologyCellularComponent	phospholipid-translocating ATPase complex	ATP11B ATP8A2	9.25e-04	14	68	2	GO:1990531
GeneOntologyCellularComponent	azurophil granule membrane	ATP11B HLA-H VAMP8	9.40e-04	59	68	3	GO:0035577
GeneOntologyCellularComponent	Golgi cisterna	HLA-A HLA-H GOLT1A TMEM87A	9.84e-04	135	68	4	GO:0031985
GeneOntologyCellularComponent	apical plasma membrane	ABCC4 ADRB2 GJB6 PKHD1 MARVELD2 SLC6A14 VAMP3	1.01e-03	487	68	7	GO:0016324
GeneOntologyCellularComponent	coated vesicle	FZD4 ADRB2 HLA-A HLA-H VAMP8 VAMP3	1.12e-03	360	68	6	GO:0030135
GeneOntologyCellularComponent	clathrin-coated vesicle membrane	FZD4 ADRB2 VAMP8 VAMP3	1.35e-03	147	68	4	GO:0030665
GeneOntologyCellularComponent	cis-Golgi network membrane	HLA-A HLA-H	1.37e-03	17	68	2	GO:0033106
GeneOntologyCellularComponent	external side of plasma membrane	ABCC4 HTR2C HLA-A ACKR3 BTN1A1 HLA-H PKHD1	1.46e-03	519	68	7	GO:0009897
GeneOntologyCellularComponent	endocytic vesicle	FZD4 ADRB2 HLA-A HLA-H VAMP8 VAMP3	1.55e-03	384	68	6	GO:0030139
GeneOntologyCellularComponent	phagocytic vesicle	HLA-A HLA-H VAMP8 VAMP3	1.72e-03	157	68	4	GO:0045335
GeneOntologyCellularComponent	side of membrane	ABCC4 HTR2C HLA-A ACKR3 BTN1A1 HLA-H PKHD1 NCAM2 CD160	2.04e-03	875	68	9	GO:0098552
GeneOntologyCellularComponent	Golgi membrane	ATP7B HLA-A TMEM87B ATP8A2 HLA-H TVP23B GOLT1A TMEM87A	2.30e-03	721	68	8	GO:0000139
GeneOntologyCellularComponent	Golgi stack	HLA-A HLA-H GOLT1A TMEM87A	2.34e-03	171	68	4	GO:0005795
GeneOntologyCellularComponent	Golgi medial cisterna	HLA-A HLA-H	2.52e-03	23	68	2	GO:0005797
GeneOntologyCellularComponent	receptor complex	ADRB2 HTR2C GPR61 SLITRK5 GPR37L1 GABBR1 IFNL1	2.77e-03	581	68	7	GO:0043235
GeneOntologyCellularComponent	Golgi apparatus subcompartment	ATP7B HLA-A HLA-H GOLT1A TMEM87A VAMP3	3.16e-03	443	68	6	GO:0098791
GeneOntologyCellularComponent	MHC protein complex	HLA-A HLA-H	3.22e-03	26	68	2	GO:0042611
GeneOntologyCellularComponent	specific granule membrane	TARM1 ADGRG3 VAMP8	3.26e-03	91	68	3	GO:0035579
GeneOntologyCellularComponent	basolateral plasma membrane	ABCC4 ATP7B MARVELD2 VAMP8 CHRM3	3.86e-03	320	68	5	GO:0016323
GeneOntologyCellularComponent	endolysosome	LGMN TPCN1	4.28e-03	30	68	2	GO:0036019
GeneOntologyCellularComponent	lumenal side of endoplasmic reticulum membrane	HLA-A HLA-H	5.79e-03	35	68	2	GO:0098553
GeneOntologyCellularComponent	basal plasma membrane	ABCC4 ATP7B MARVELD2 VAMP8 CHRM3	5.90e-03	354	68	5	GO:0009925
GeneOntologyCellularComponent	secretory vesicle	TARM1 ABCC4 ADGRG3 ADRB2 ATP11B SLC6A17 HLA-H VAMP8 GABBR1 VAMP3	6.76e-03	1246	68	10	GO:0099503
GeneOntologyCellularComponent	clathrin-coated vesicle	FZD4 ADRB2 VAMP8 VAMP3	7.44e-03	237	68	4	GO:0030136
GeneOntologyCellularComponent	basal part of cell	ABCC4 ATP7B MARVELD2 VAMP8 CHRM3	7.73e-03	378	68	5	GO:0045178
GeneOntologyCellularComponent	endoplasmic reticulum exit site	HLA-A HLA-H	8.25e-03	42	68	2	GO:0070971
GeneOntologyCellularComponent	lumenal side of membrane	HLA-A HLA-H	1.07e-02	48	68	2	GO:0098576
Domain	GPCR_Rhodpsn_7TM	ADRB2 HTR2C GPR61 OR1B1 ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 OR2Z1 NMBR CHRM3 OR8G1	7.03e-08	670	66	14	IPR017452
Domain	7tm_1	ADRB2 HTR2C GPR61 OR1B1 ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 OR2Z1 NMBR CHRM3 OR8G1	8.00e-08	677	66	14	PF00001
Domain	G_PROTEIN_RECEP_F1_1	ADRB2 HTR2C GPR61 OR1B1 ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 OR2Z1 NMBR CHRM3 OR8G1	9.24e-08	685	66	14	PS00237
Domain	G_PROTEIN_RECEP_F1_2	ADRB2 HTR2C GPR61 OR1B1 ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 OR2Z1 NMBR CHRM3 OR8G1	1.03e-07	691	66	14	PS50262
Domain	GPCR_Rhodpsn	ADRB2 HTR2C GPR61 OR1B1 ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 OR2Z1 NMBR CHRM3 OR8G1	1.05e-07	692	66	14	IPR000276
Domain	Lung_7-TM_R	TMEM87B TMEM87A	7.35e-05	4	66	2	PF06814
Domain	GPR107-like	TMEM87B TMEM87A	7.35e-05	4	66	2	IPR009637
Domain	MHC_I_C	HLA-A HLA-H	1.83e-04	6	66	2	PF06623
Domain	Synaptobrevin/VAMP	VAMP8 VAMP3	1.83e-04	6	66	2	IPR016444
Domain	MHC_I_a_C	HLA-A HLA-H	1.83e-04	6	66	2	IPR010579
Domain	-	ATP7B ATP11B ATP8A2	1.94e-04	32	66	3	2.70.150.10
Domain	-	ATP7B ATP11B ATP8A2	1.94e-04	32	66	3	3.40.1110.10
Domain	ATPase_P-typ_cyto_domN	ATP7B ATP11B ATP8A2	2.54e-04	35	66	3	IPR023299
Domain	ATPase_P-typ_P_site	ATP7B ATP11B ATP8A2	2.77e-04	36	66	3	IPR018303
Domain	P_typ_ATPase	ATP7B ATP11B ATP8A2	2.77e-04	36	66	3	IPR001757
Domain	ATPASE_E1_E2	ATP7B ATP11B ATP8A2	2.77e-04	36	66	3	PS00154
Domain	ATPase_P-typ_transduc_dom_A	ATP7B ATP11B ATP8A2	3.01e-04	37	66	3	IPR008250
Domain	E1-E2_ATPase	ATP7B ATP11B ATP8A2	3.01e-04	37	66	3	PF00122
Domain	SYNAPTOBREVIN	VAMP8 VAMP3	3.40e-04	8	66	2	PS00417
Domain	-	VAMP8 VAMP3	3.40e-04	8	66	2	1.10.3840.10
Domain	Synaptobrevin	VAMP8 VAMP3	6.63e-04	11	66	2	PF00957
Domain	7TM_GPCR_Srsx	ADRB2 HTR2C NMBR CHRM3	6.63e-04	112	66	4	SM01381
Domain	V_SNARE	VAMP8 VAMP3	7.93e-04	12	66	2	PS50892
Domain	Synaptobrevin	VAMP8 VAMP3	9.36e-04	13	66	2	IPR001388
Domain	P_typ_ATPase_c	ATP11B ATP8A2	1.09e-03	14	66	2	IPR032630
Domain	P-type_ATPase_N	ATP11B ATP8A2	1.09e-03	14	66	2	IPR032631
Domain	P-type_ATPase_IV	ATP11B ATP8A2	1.09e-03	14	66	2	IPR006539
Domain	PhoLip_ATPase_C	ATP11B ATP8A2	1.09e-03	14	66	2	PF16212
Domain	PhoLip_ATPase_N	ATP11B ATP8A2	1.09e-03	14	66	2	PF16209
Domain	GPCR_2-like	FZD4 ADGRG3 ADGRD2	1.25e-03	60	66	3	IPR017981
Domain	GPCR_2_secretin-like	FZD4 ADGRG3 ADGRD2	1.25e-03	60	66	3	IPR000832
Domain	G_PROTEIN_RECEP_F2_4	FZD4 ADGRG3 ADGRD2	1.31e-03	61	66	3	PS50261
Domain	-	ATP7B ATP11B ATP8A2	1.51e-03	64	66	3	3.40.50.1000
Domain	NA_NEUROTRAN_SYMP_2	SLC6A17 SLC6A14	1.81e-03	18	66	2	PS00754
Domain	NA_NEUROTRAN_SYMP_3	SLC6A17 SLC6A14	2.02e-03	19	66	2	PS50267
Domain	SNF	SLC6A17 SLC6A14	2.02e-03	19	66	2	PF00209
Domain	Na/ntran_symport	SLC6A17 SLC6A14	2.02e-03	19	66	2	IPR000175
Domain	NA_NEUROTRAN_SYMP_1	SLC6A17 SLC6A14	2.02e-03	19	66	2	PS00610
Domain	MHC_I	HLA-A HLA-H	2.47e-03	21	66	2	PF00129
Domain	MHC_I_a_a1/a2	HLA-A HLA-H	2.47e-03	21	66	2	IPR001039
Domain	HAD-like_dom	ATP7B ATP11B ATP8A2	2.75e-03	79	66	3	IPR023214
Domain	Ig-like_fold	TARM1 HLA-A BTN1A1 FNDC5 HLA-H PKHD1 NCAM2 CD160	3.33e-03	706	66	8	IPR013783
Domain	GPS	ADGRG3 ADGRD2	6.41e-03	34	66	2	SM00303
Domain	GPS	ADGRG3 ADGRD2	6.79e-03	35	66	2	PF01825
Domain	GPS	ADGRG3 ADGRD2	7.17e-03	36	66	2	PS50221
Domain	GPS	ADGRG3 ADGRD2	7.56e-03	37	66	2	IPR000203
Domain	IG_LIKE	TARM1 HLA-A BTN1A1 HLA-H NCAM2 CD160	7.68e-03	491	66	6	PS50835
Domain	Ig-like_dom	TARM1 HLA-A BTN1A1 HLA-H NCAM2 CD160	8.60e-03	503	66	6	IPR007110
Domain	-	TARM1 HLA-A BTN1A1 FNDC5 PKHD1 NCAM2 CD160	8.74e-03	663	66	7	2.60.40.10
Domain	G_PROTEIN_RECEP_F2_1	ADGRG3 ADGRD2	8.80e-03	40	66	2	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRG3 ADGRD2	8.80e-03	40	66	2	PS50227
Domain	GPCR_2_extracellular_dom	ADGRG3 ADGRD2	8.80e-03	40	66	2	IPR001879
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	ADRB2 HTR2C ACKR3 FPR3 GPR37L1 NMBR CHRM3 GABBR1 OR8G1	3.76e-08	186	55	9	MM15994
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	ADRB2 HTR2C ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 NMBR GOLT1A CHRM3	5.13e-08	333	55	11	MM14963
Pathway	WP_GPCRS_NONODORANT	FZD4 ADRB2 HTR2C ACKR3 NPSR1 HRH4 TACR1 NMBR CHRM3 GABBR1	6.69e-08	266	55	10	MM15843
Pathway	REACTOME_GPCR_LIGAND_BINDING	ADRB2 HTR2C ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 NMBR GOLT1A CHRM3 GABBR1	7.44e-08	430	55	12	MM15160
Pathway	REACTOME_GPCR_LIGAND_BINDING	FZD4 ADRB2 HTR2C ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 NMBR CHRM3 GABBR1	1.66e-07	463	55	12	M507
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	ADRB2 HTR2C ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 NMBR CHRM3	4.95e-07	330	55	10	M18334
Pathway	REACTOME_ER_PHAGOSOME_PATHWAY	HLA-A HLA-H VAMP8 VAMP3	6.09e-07	18	55	4	MM14525
Pathway	REACTOME_SIGNALING_BY_GPCR	ADRB2 HTR2C ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 NMBR GOLT1A CHRM3 GABBR1	5.55e-06	646	55	12	MM14962
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	ADRB2 HTR2C FPR3 HRH4 TACR1 NMBR CHRM3 GABBR1	9.62e-06	272	55	8	M13380
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	ACKR3 FPR3 NPSR1 GPR37L1 TACR1 NMBR GOLT1A	1.08e-05	197	55	7	MM14970
Pathway	REACTOME_SIGNALING_BY_GPCR	FZD4 ADRB2 HTR2C ACKR3 FPR3 NPSR1 GPR37L1 HRH4 TACR1 NMBR CHRM3 GABBR1	1.29e-05	702	55	12	M746
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	ADRB2 HTR2C HRH4 CHRM3	2.08e-05	42	55	4	M5868
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	ADRB2 HTR2C HRH4 CHRM3	2.08e-05	42	55	4	MM14971
Pathway	WP_GPCRS_OTHER	ADRB2 GPR61 HRH4 CHRM3 OR8G1	3.01e-05	93	55	5	M39629
Pathway	REACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS	FZD4 ADRB2 TACR1 VAMP8 VAMP3	4.69e-05	102	55	5	MM15498
Pathway	REACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS	FZD4 ADRB2 TACR1 VAMP8 VAMP3	5.39e-05	105	55	5	M27752
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	ADRB2 HTR2C ACKR3 FPR3 GPR37L1 NMBR CHRM3	6.38e-05	260	55	7	M39397
Pathway	REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS	ACKR3 FPR3 NPSR1 GPR37L1 TACR1 NMBR	1.13e-04	197	55	6	M12289
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	HTR2C NPSR1 TACR1 NMBR GOLT1A CHRM3	1.61e-04	210	55	6	MM15043
Pathway	REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION	HLA-A HLA-H VAMP8 VAMP3	2.16e-04	76	55	4	MM14526
Pathway	REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS	FZD4 ADRB2 TACR1 VAMP8 VAMP3	2.24e-04	142	55	5	MM15499
Pathway	WP_MONOAMINE_GPCRS	ADRB2 HTR2C CHRM3	2.34e-04	31	55	3	MM15871
Pathway	REACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS	FZD4 ADRB2 TACR1 VAMP8 VAMP3	2.47e-04	145	55	5	M27753
Pathway	WP_MONOAMINE_GPCRS	ADRB2 HTR2C CHRM3	2.82e-04	33	55	3	M39585
Pathway	WP_GPCRS_OTHER	ADRB2 GPR37L1 GABBR1 OR8G1	5.28e-04	96	55	4	MM15939
Pathway	REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY	HLA-A HLA-H	5.29e-04	9	55	2	MM14527
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY	HTR2C TACR1 CHRM3	9.67e-04	50	55	3	M47951
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP7B ATP11B ATP8A2	1.28e-03	55	55	3	M971
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP7B ATP11B ATP8A2	1.42e-03	57	55	3	MM15643
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	HTR2C NPSR1 TACR1 NMBR CHRM3	1.54e-03	217	55	5	M18437
Pathway	WP_GPCRS_PEPTIDE	FPR3 TACR1 NMBR	2.56e-03	70	55	3	MM15959
Pathway	BIOCARTA_CTL_PATHWAY	HLA-A HLA-H	2.71e-03	20	55	2	MM1374
Pathway	WP_PEPTIDE_GPCRS	FPR3 TACR1 NMBR	3.11e-03	75	55	3	M39696
Pubmed	Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.	ADRB2 HTR2C ACKR3 HRH4 NMBR CHRM3	2.73e-06	200	68	6	18240029
Pubmed	Differential expression of the β2-adrenoreceptor and M3-cholinoreceptor genes in bronchial mucosa of patients with asthma and chronic obstructive pulmonary disease.	ADRB2 CHRM3	3.77e-06	2	68	2	22192964
Pubmed	Constitutive internalization of G protein-coupled receptors and G proteins via clathrin-independent endocytosis.	ADRB2 CHRM3	3.77e-06	2	68	2	19033440
Pubmed	SLC6A14 and 5-HTR2C polymorphisms are associated with food intake and nutritional status in children.	HTR2C SLC6A14	3.77e-06	2	68	2	26160208
Pubmed	Post-Golgi anterograde transport requires GARP-dependent endosome-to-TGN retrograde transport.	TMEM87B TMEM87A	3.77e-06	2	68	2	26157166
Pubmed	A nucleotide deletion in exon 4 is responsible for an HLA-A null allele (A*0105N).	HLA-A HLA-H	3.77e-06	2	68	2	10519371
Pubmed	Murine candidate bleomycin induced pulmonary fibrosis susceptibility genes identified by gene expression and sequence analysis of linkage regions.	HLA-A HLA-H GABBR1	9.27e-06	21	68	3	15937080
Pubmed	A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP).	ADRB2 TACR1 CHRM3	9.27e-06	21	68	3	15452121
Pubmed	Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.	HLA-A GABBR1	1.13e-05	3	68	2	19664746
Pubmed	VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cells.	VAMP8 VAMP3	1.13e-05	3	68	2	22144578
Pubmed	Biochemical and biophysical characterization of serotonin 5-HT2C receptor homodimers on the plasma membrane of living cells.	ADRB2 HTR2C	1.13e-05	3	68	2	15518545
Pubmed	Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms.	VAMP8 VAMP3	1.13e-05	3	68	2	18250339
Pubmed	Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reaction.	VAMP8 VAMP3	1.13e-05	3	68	2	17065550
Pubmed	Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction.	ADRB2 HTR2C	1.13e-05	3	68	2	30157263
Pubmed	Increased formation of VAMP-3-containing SNARE complexes in mast cells from VAMP-8 deficient cells. appetite.	VAMP8 VAMP3	1.13e-05	3	68	2	19274433
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	ATP7B DPY19L1 TMEM87B SLITRK5 TVP23B MARVELD2 VAMP8 FITM2 TMEM87A VAMP3	1.56e-05	952	68	10	38569033
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	ADGRG3 NPSR1 GPR37L1 ADGRD2	1.80e-05	79	68	4	12679517
Pubmed	Combining global genome and transcriptome approaches to identify the candidate genes of small-effect quantitative trait loci in collagen-induced arthritis.	HLA-H ETNK1 GABBR1	2.02e-05	27	68	3	17244351
Pubmed	The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.	VAMP8 VAMP3	2.25e-05	4	68	2	22118466
Pubmed	Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7.	VAMP8 VAMP3	2.25e-05	4	68	2	22589474
Pubmed	Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox.	ADRB2 CHRM3	2.25e-05	4	68	2	12925702
Pubmed	β1/2 or M2/3 Receptors Are Required for Different Gastrointestinal Motility Responses Induced by Acupuncture at Heterotopic or Homotopic Acupoints.	ADRB2 CHRM3	2.25e-05	4	68	2	27978539
Pubmed	MRP4 and CFTR in the regulation of cAMP and β-adrenergic contraction in cardiac myocytes.	ABCC4 ADRB2	2.25e-05	4	68	2	22381067
Pubmed	Additive role of tiotropium in severe asthmatics and Arg16Gly in ADRB2 as a potential marker to predict response.	ADRB2 CHRM3	2.25e-05	4	68	2	19183167
Pubmed	Variations in the requirement for v-SNAREs in GLUT4 trafficking in adipocytes.	VAMP8 VAMP3	2.25e-05	4	68	2	19759285
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	ADRB2 HTR2C NCAM2 TACR1 CHRM3 GABBR1	2.74e-05	300	68	6	19086053
Pubmed	Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis.	VAMP8 VAMP3	3.75e-05	5	68	2	26209658
Pubmed	Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity.	ADRB2 CHRM3	3.75e-05	5	68	2	20197056
Pubmed	Absence of substance P and the sympathetic nervous system impact on bone structure and chondrocyte differentiation in an adult model of endochondral ossification.	ADRB2 TACR1	3.75e-05	5	68	2	25063231
Pubmed	Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.	ABCC4 ADRB2	3.75e-05	5	68	2	25401477
Pubmed	Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A.	TMEM87B TMEM87A	3.75e-05	5	68	2	36373655
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ADRB2 GPR61 SLITRK5 GPR37L1	4.73e-05	101	68	4	23382219
Pubmed	Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs.	VAMP8 VAMP3	5.62e-05	6	68	2	11786915
Pubmed	Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.	ABCC4 ADRB2 HTR2C HLA-A	6.14e-05	108	68	4	19956635
Pubmed	DNA sequences of mouse H-2 and Qa genes.	HLA-H FKBP4	7.86e-05	7	68	2	2592022
Pubmed	Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse.	HLA-A HLA-H	7.86e-05	7	68	2	6088985
Pubmed	Soluble NSF attachment protein receptors (SNAREs) in RBL-2H3 mast cells: functional role of syntaxin 4 in exocytosis and identification of a vesicle-associated membrane protein 8-containing secretory compartment.	VAMP8 VAMP3	7.86e-05	7	68	2	10820264
Pubmed	Molecular organization of the D-Qa region of t-haplotypes suggests that recombination is an important mechanism for generating genetic diversity of the major histocompatibility complex.	HLA-A HLA-H	7.86e-05	7	68	2	1686840
Pubmed	Generation of a functional cDNA encoding the LdH2 class-I molecule by using a single-LTR retroviral shuttle vector.	HLA-A HLA-H	7.86e-05	7	68	2	1705528
Pubmed	Further studies on polymorphic expression of GM1 and GD1a in mouse liver. The presence of a third allele on the Ggm-1 locus.	HLA-A HLA-H	7.86e-05	7	68	2	2808323
Pubmed	CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.	HLA-A HLA-H	7.86e-05	7	68	2	21088134
Pubmed	MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling.	HLA-A HLA-H	7.86e-05	7	68	2	34181639
Pubmed	The Tla locus: a new allele and antigenic specificity.	HLA-A HLA-H	7.86e-05	7	68	2	69663
Pubmed	MHC class I genes are not imprinted in the mouse placenta.	HLA-A HLA-H	7.86e-05	7	68	2	8206527
Pubmed	Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense.	HLA-A HLA-H	7.86e-05	7	68	2	12459592
Pubmed	Multiple sequences related to classical histocompatibility antigens in the mouse genome.	HLA-A HLA-H	7.86e-05	7	68	2	6264319
Pubmed	Conservation and diversity in the class I genes of the major histocompatibility complex: sequence analysis of a Tlab gene and comparison with a Tlac gene.	HLA-A HLA-H	7.86e-05	7	68	2	3456611
Pubmed	Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules.	HLA-A HLA-H	7.86e-05	7	68	2	15809355
Pubmed	Sequence analysis of the C3H H-2K1k gene: relationship to the H-2 loci.	HLA-A HLA-H	7.86e-05	7	68	2	2714856
Pubmed	Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells.	HLA-A HLA-H	7.86e-05	7	68	2	10500200
Pubmed	The murine family of gut-restricted class Ib MHC includes alternatively spliced isoforms of the proposed HLA-G homolog, "blastocyst MHC".	HLA-A HLA-H	7.86e-05	7	68	2	16210630
Pubmed	Structural analysis of H-2Kf and H-2Kfm1 by using H-2K locus-specific sequences.	HLA-A HLA-H	7.86e-05	7	68	2	2391419
Pubmed	Thymus-leukemia (TL) antigens of the mouse. Analysis of TL mRNA and TL cDNA TL+ and TL- strains.	HLA-A HLA-H	7.86e-05	7	68	2	3840195
Pubmed	Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmunosuppressed adult rats.	HLA-A HLA-H	7.86e-05	7	68	2	15671142
Pubmed	GENETIC BASIS OF SUSCEPTIBILITY TO VIRAL LEUKAEMOGENESIS.	HLA-A HLA-H	7.86e-05	7	68	2	14215561
Pubmed	Tolerance and MHC restriction in transgenic mice expressing a MHC class I gene in erythroid cells.	HLA-A HLA-H	7.86e-05	7	68	2	1540549
Pubmed	Mouse histocompatibility genes: structure and organisation of a Kd gene.	HLA-A HLA-H	7.86e-05	7	68	2	11894934
Pubmed	Overexpression of MHC class I heavy chain protein in young skeletal muscle leads to severe myositis: implications for juvenile myositis.	HLA-A HLA-H	7.86e-05	7	68	2	19700752
Pubmed	A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity.	HLA-A HLA-H	7.86e-05	7	68	2	28234229
Pubmed	The DNA sequence of the H-2kb gene: evidence for gene conversion as a mechanism for the generation of polymorphism in histocompatibilty antigens.	HLA-A HLA-H	7.86e-05	7	68	2	11894963
Pubmed	Interaction of H-2Db with mutant histocompatibility gene H (KH-11) in the mouse.	HLA-A HLA-H	7.86e-05	7	68	2	6242891
Pubmed	Immune-privileged embryonic Swiss mouse STO and STO cell-derived progenitor cells: major histocompatibility complex and cell differentiation antigen expression patterns resemble those of human embryonic stem cell lines.	HLA-A HLA-H	7.86e-05	7	68	2	16836618
Pubmed	Skewing of the NK cell repertoire by MHC class I via quantitatively controlled enrichment and contraction of specific Ly49 subsets.	HLA-A HLA-H	7.86e-05	7	68	2	22287714
Pubmed	Characterization of a severe parenchymal phenotype of experimental autoimmune encephalomyelitis in (C57BL6xB10.PL)F1 mice.	HLA-A HLA-H	7.86e-05	7	68	2	17512611
Pubmed	Family organization of mouse H-2 class I genes.	HLA-A HLA-H	7.86e-05	7	68	2	3997208
Pubmed	The murine MHC class I genes, H-2Dq and H-2Lq, are strikingly homologous to each other, H-2Ld, and two genes reported to encode tumor-specific antigens.	HLA-A HLA-H	7.86e-05	7	68	2	3263465
Pubmed	Amino acid sequence of residues 1-98 of the K-2Kb murine major histocompatibility alloantigen: comparison with H-2Kb and H-2db reveals extensive localized differences.	HLA-A HLA-H	7.86e-05	7	68	2	7018573
Pubmed	Molecular basis of the dm1 mutation in the major histocompatibility complex of the mouse: a D/L hybrid gene.	HLA-A HLA-H	7.86e-05	7	68	2	2997361
Pubmed	Expression of GM1 and GD1a in mouse liver is linked to the H-2 complex on chromosome 17.	HLA-A HLA-H	7.86e-05	7	68	2	6671979
Pubmed	The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells.	HLA-A HLA-H	7.86e-05	7	68	2	18974374
Pubmed	Nucleotide sequences of three H-2K and three H-2D complementary DNA clones coding mouse class I MHC heavy chain proteins.	HLA-A HLA-H	7.86e-05	7	68	2	9869916
Pubmed	The H-2Kk MHC peptide-binding groove anchors the backbone of an octameric antigenic peptide in an unprecedented mode.	HLA-A HLA-H	7.86e-05	7	68	2	16148128
Pubmed	The role of the MHC on resistance to group a streptococci in mice.	HLA-A HLA-H	7.86e-05	7	68	2	16148132
Pubmed	Qat-4 and Qat-5, new murine T-cell antigens governed by the Tla region and identified by monoclonal antibodies.	HLA-A HLA-H	7.86e-05	7	68	2	312902
Pubmed	Induction of the H-2 D antigen during B cell activation.	HLA-A HLA-H	7.86e-05	7	68	2	2642506
Pubmed	A complex major histocompatibility complex D locus variant generated by an unusual recombination mechanism in mice.	HLA-A HLA-H	7.86e-05	7	68	2	9037062
Pubmed	Nucleic acid sequences of the H-2Ks and H-2Ksm1 genes.	HLA-A HLA-H	7.86e-05	7	68	2	1840571
Pubmed	Impaired response to Listeria in H2-M3-deficient mice reveals a nonredundant role of MHC class Ib-specific T cells in host defense.	HLA-A HLA-H	7.86e-05	7	68	2	16476767
Pubmed	Influence of xenogeneic beta2-microglobulin on functional recognition of H-2Kb by the NK cell inhibitory receptor Ly49C.	HLA-A HLA-H	7.86e-05	7	68	2	16148097
Pubmed	Serological analysis of H-2 mutations using monoclonal antibodies.	HLA-A HLA-H	7.86e-05	7	68	2	6084033
Pubmed	Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice.	HLA-A HLA-H	7.86e-05	7	68	2	20957233
Pubmed	Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides.	HLA-A HLA-H	7.86e-05	7	68	2	11580250
Pubmed	V beta T cell repertoire of CD8+ splenocytes selected on nonpolymorphic MHC class I molecules.	HLA-A HLA-H	7.86e-05	7	68	2	11086076
Pubmed	Asymptomatic HLA-A*02:01-restricted epitopes from herpes simplex virus glycoprotein B preferentially recall polyfunctional CD8+ T cells from seropositive asymptomatic individuals and protect HLA transgenic mice against ocular herpes.	HLA-A HLA-H	7.86e-05	7	68	2	24101547
Pubmed	Ligand-dependent inhibition of CD1d-restricted NKT cell development in mice transgenic for the activating receptor Ly49D.	HLA-A HLA-H	7.86e-05	7	68	2	12682111
Pubmed	The nucleotide sequence of the H-2K gene of C3Hf/HeN mice.	HLA-A HLA-H	7.86e-05	7	68	2	3335396
Pubmed	HLA-B*0702 transgenic, H-2KbDb double-knockout mice: phenotypical and functional characterization in response to influenza virus.	HLA-A HLA-H	7.86e-05	7	68	2	12750360
Pubmed	Alternative RNA splicing in expression of the H-2K gene.	HLA-A HLA-H	7.86e-05	7	68	2	6689056
Pubmed	The multi-locus H-2Dw16 region has an organization distinct from the Dd region.	HLA-A HLA-H	7.86e-05	7	68	2	1348492
Pubmed	H2-M3-restricted CD8+ T cells are not required for MHC class Ib-restricted immunity against Listeria monocytogenes.	HLA-A HLA-H	7.86e-05	7	68	2	16461341
Pubmed	Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6.	HLA-A HLA-H	7.86e-05	7	68	2	18416856
Pubmed	Convergent recombination shapes the clonotypic landscape of the naive T-cell repertoire.	HLA-A HLA-H	7.86e-05	7	68	2	20974936
Pubmed	The role of peptides in T cell alloreactivity is determined by self-major histocompatibility complex molecules.	HLA-A HLA-H	7.86e-05	7	68	2	10704462
Pubmed	Coiled-coil interactions are required for post-Golgi R-SNARE trafficking.	VAMP8 VAMP3	7.86e-05	7	68	2	19557002
Pubmed	A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains.	HLA-A HLA-H	7.86e-05	7	68	2	6895187
Pubmed	West Nile virus T-cell ligand sequences shared with other flaviviruses: a multitude of variant sequences as potential altered peptide ligands.	HLA-A HLA-H	7.86e-05	7	68	2	22573867
Pubmed	Genetic control of corticosteroid side-chain isomerase activity in the mouse.	HLA-A HLA-H	7.86e-05	7	68	2	6822218
Pubmed	A novel H-2K splice form: predictions for other alternative H-2 splicing events.	HLA-A HLA-H	7.86e-05	7	68	2	2908875
Pubmed	The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.	HLA-A HLA-H	7.86e-05	7	68	2	15210799
Pubmed	Comparison of exon 5 sequences from 35 class I genes of the BALB/c mouse.	HLA-A HLA-H	7.86e-05	7	68	2	2584927
Interaction	TM9SF3 interactions	GDPD5 ADRB2 HTR2C LMBR1L FNDC5 TACR1	4.63e-06	143	61	6	int:TM9SF3
Interaction	TMEM147 interactions	HTR2C GPR61 FNDC5 GPR37L1 TACR1	6.94e-06	88	61	5	int:TMEM147
Interaction	CRELD1 interactions	ABCC4 HTR2C LMBR1L DPY19L1 FITM2 GABBR1	9.81e-06	163	61	6	int:CRELD1
Interaction	SIGMAR1 interactions	LMBR1L FNDC5 TACR1 GOLT1A TMEM87A	2.78e-05	117	61	5	int:SIGMAR1
Interaction	GPR61 interactions	GPR61 GJB6 EMP3	3.90e-05	22	61	3	int:GPR61
Interaction	TSPAN12 interactions	TMEM182 GPR37L1 EMP3	3.90e-05	22	61	3	int:TSPAN12
Interaction	TAPBP interactions	HTR2C HLA-A LMBR1L FNDC5	5.05e-05	67	61	4	int:TAPBP
Interaction	NLRP11 interactions	NLRP11 FKBP4	5.39e-05	4	61	2	int:NLRP11
Interaction	ALG5 interactions	LMBR1L FNDC5 EMP3 FITM2	6.00e-05	70	61	4	int:ALG5
Interaction	LHFPL5 interactions	ADGRG3 GJB6 GPR37L1 EMP3 VAMP3	7.01e-05	142	61	5	int:LHFPL5
Interaction	SCAMP4 interactions	GDPD5 LMBR1L EMP3	1.12e-04	31	61	3	int:SCAMP4
Interaction	FADS1 interactions	HTR2C LMBR1L FNDC5 TACR1	1.40e-04	87	61	4	int:FADS1
Interaction	NSF interactions	ADRB2 LMBR1L FNDC5 VAMP8 GABBR1 VAMP3	1.45e-04	264	61	6	int:NSF
Cytoband	1p13.3	GPR61 SLC6A17 CHI3L2	1.52e-04	69	68	3	1p13.3
Cytoband	13q12	ATP8A2 GJB6	5.84e-04	24	68	2	13q12
GeneFamily	Vesicle associated membrane proteins	VAMP8 VAMP3	1.50e-04	7	49	2	12
GeneFamily	ATPase phospholipid transporting	ATP11B ATP8A2	7.39e-04	15	49	2	1210
GeneFamily	Histocompatibility complex\|C1-set domain containing	HLA-A HLA-H	6.33e-03	44	49	2	588
Coexpression	GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_UP	ADGRG3 ADRB2 HTR2C DPY19L1 TMEM87B GABBR1	1.28e-06	137	66	6	M6346
Coexpression	TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN	LGMN ADGRG3 HTR2C FPR3 HRH4 ETNK1	1.34e-05	206	66	6	M9740
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC45A2 TACR1 NMBR CD160	1.54e-06	55	68	4	948f26841f18d2d45f74c7c0c7b5be10737a4f43
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC45A2 TACR1 NMBR CD160	1.54e-06	55	68	4	616be3c334949ab0264293b9771d494381d74fb4
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC45A2 TACR1 NMBR CD160	1.54e-06	55	68	4	ed14bdb80cf2ff171b0dfc391ac0b150da344992
ToppCell	15-Trachea-Immune-Hematopoietic,_Natural_Killer_Cell\|Trachea / Age, Tissue, Lineage and Cell class	ADGRG3 ADRB2 EMP3 CD160 IFNL1	6.80e-06	173	68	5	6884af1492e8a3bb92a33303d4d5ec3343e88b00
ToppCell	primary_visual_cortex-Non-neuronal\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NWD1 GJB6 GPR37L1 TMEM176A VAMP8	7.39e-06	176	68	5	2c92f3f55d668cfe80051b5128160a6dc3aec4e8
ToppCell	356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LGMN TMEM87B FPR3 TMEM176A VAMP8	1.07e-05	190	68	5	d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCell	Monocytes-Phagocytic_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	LGMN HLA-A FPR3 EMP3 VAMP8	1.18e-05	194	68	5	40dbfdf1d7e6b73d120d8f802f08e573fe9a739e
ToppCell	normal_Lung-Epithelial_cells-AT2\|Epithelial_cells / Location, Cell class and cell subclass	LGMN ATP8A2 CHI3L2 GOLT1A SLC6A14	1.21e-05	195	68	5	81e13fe337f1d0a83d0deb86a0df797d306cd24d
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LGMN CHI3L2 GOLT1A TMEM87A SLC6A14	1.27e-05	197	68	5	f3ca63c7902d7530a29a85eb54f69b303031d150
ToppCell	LAM-Epithelial-AT2\|Epithelial / Condition, Lineage and Cell class	LGMN ATP8A2 CHI3L2 GOLT1A SLC6A14	1.27e-05	197	68	5	27e6eb7bbc27e7635df1aae7c7d75f8a3f1b1cc2
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LGMN CHI3L2 GOLT1A TMEM87A SLC6A14	1.27e-05	197	68	5	f98720cab066579fdac3ba24fb6fe4c5759dae4e
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D3\|390C / Donor, Lineage, Cell class and subclass (all cells)	ADGRG3 HLA-A GPR37L1 CD160	6.80e-05	143	68	4	10473c0f030d5ff760263042dc4b584787cb4a7f
ToppCell	BLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)\|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ADRB2 HLA-A EMP3 CD160	7.18e-05	145	68	4	6dd81d53d006fcc206a10969374a11c372f92133
ToppCell	metastatic_Lymph_Node-T/NK_cells-CD8_low_T\|T/NK_cells / Location, Cell class and cell subclass	NWD1 ADRB2 ACKR3 CHI3L2	7.77e-05	148	68	4	db046a02a00829910bf9d7dbda068e730aa78f00
ToppCell	facs-Trachea-nan-24m-Myeloid-granulocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TARM1 ADGRG3 HRH4 SLC45A2	8.40e-05	151	68	4	26fd55efb647c41436416d45952ee97b050e632c
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NWD1 GJB6 GPR37L1 TMEM176A	8.84e-05	153	68	4	95b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NWD1 GJB6 GPR37L1 TMEM176A	8.84e-05	153	68	4	b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NWD1 GJB6 GPR37L1 TMEM176A	8.84e-05	153	68	4	3ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCell	droplet-Fat-Mat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 GOLT1A ENTPD8 SLC6A14	9.53e-05	156	68	4	cfd7f56f3155db677684827607e9008e975dbe70
ToppCell	droplet-Fat-Mat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 GOLT1A ENTPD8 SLC6A14	9.53e-05	156	68	4	0d79b4172896574b00faf00e87254f68d76f5512
ToppCell	droplet-Fat-Mat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKHD1 GOLT1A ENTPD8 SLC6A14	9.53e-05	156	68	4	f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	ABCC4 GJB6 TACR1 SLC6A14	1.13e-04	163	68	4	d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LGMN CHI3L2 TMEM87A SLC6A14	1.16e-04	164	68	4	beaa13a75c3bb72446c85084d75e9fe3f15fd3d4
ToppCell	343B-Epithelial_cells-Epithelial-A_(AT2)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LGMN CHI3L2 TMEM87A SLC6A14	1.16e-04	164	68	4	d005cfd821b87548b075120bffe65a0be9860463
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2C DPY19L1 NPSR1 GOLT1A	1.24e-04	167	68	4	c7d1e84af1f4d7430858287520ac2cfa36203642
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2C DPY19L1 NPSR1 GOLT1A	1.24e-04	167	68	4	4e613be2b3ba01160b0c0254fce3c4f72220e580
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2C DPY19L1 NPSR1 GOLT1A	1.24e-04	167	68	4	18ad85751bd892309627eefc357eb28ec5a7c300
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TARM1 ADGRG3 ADRB2 HRH4	1.33e-04	170	68	4	4b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2C DPY19L1 NPSR1 GOLT1A	1.33e-04	170	68	4	ce2fd2fbbfd152290be0cf8e513f102fdc182b41
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNK10 FNDC5 TMEM270 SLC6A14	1.33e-04	170	68	4	833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2C DPY19L1 NPSR1 GOLT1A	1.33e-04	170	68	4	ab5c6a91c371e4df15b0842828dc55039695ab06
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HTR2C DPY19L1 NPSR1 GOLT1A	1.33e-04	170	68	4	4aa9e597f6550ac8cac3137a98be58e71efd07d6
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage\|368C / Donor, Lineage, Cell class and subclass (all cells)	LGMN FPR3 VAMP8 OR8G1	1.42e-04	173	68	4	bba8265a58f8f5659dc7b9da2fe27b15033fce34
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCC4 ADRB2 FPR3 TACR1	1.42e-04	173	68	4	a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell	normal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	ADRB2 HLA-A CHI3L2 CD160	1.42e-04	173	68	4	1e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC4 GPR61 G6PC2 FITM2	1.45e-04	174	68	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D175\|Adult / Lineage, Cell type, age group and donor	NLRP11 GDPD5 SLC45A2 TACR1	1.48e-04	175	68	4	0a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRG3 ACKR3 NCAM2 SLC45A2	1.48e-04	175	68	4	9a96a946db731ba24c9be34bedebf1f4a1372b9e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRG3 ACKR3 NCAM2 SLC45A2	1.48e-04	175	68	4	54c1f080195ad8392a095e83b56a4b54073d4c0d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRG3 ACKR3 NCAM2 SLC45A2	1.48e-04	175	68	4	2b51406a2c2daa13ab4ed283ede038cd11d9e641
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 ATP7B GJB6 GPR37L1	1.62e-04	179	68	4	7ae67e1c09a4ce9b3bcec4c48ee9cf2b1cb4e339
ToppCell	3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages\|bone_marrow / Manually curated celltypes from each tissue	LGMN ACKR3 FPR3 TMEM176A	1.65e-04	180	68	4	daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCell	healthy_donor-Myeloid-Monocytic-SC_&_Eosinophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ABCC4 ADGRG3 HRH4 CHRM3	1.72e-04	182	68	4	6bd6c32c48fecd6d03ac8a09e405b3b99bdc12ae
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LGMN HLA-A FPR3 EMP3	1.76e-04	183	68	4	4cc0961a67de76b8d756cd9ffcaa98e3fe3c3a69
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRG3 CHI3L2 VAMP8 IFNL1	1.76e-04	183	68	4	c7fedb5b0c1f17b3391ce1c4a6bfca7615c359c5
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 ATP8A2 GPR37L1 NCAM2	1.83e-04	185	68	4	3d1353dbcb60e2531ef67e1bd218b7bc4d7c7c9b
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 ATP8A2 GPR37L1 NCAM2	1.83e-04	185	68	4	995a8ddc3fd8e6879d8b5de8cbdefe232d34833b
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LGMN FPR3 TMEM176A FKBP4	1.83e-04	185	68	4	0e8064bb317f26959d3c59b4f73d0c455161ccd7
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LGMN CHI3L2 GOLT1A SLC6A14	1.83e-04	185	68	4	7460387f48f33674330bd53b759681b264228f5a
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRG3 CHI3L2 VAMP8 CD160	1.87e-04	186	68	4	ed265e52e4f9b6d277b489091ecc2e629436f791
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-A ACKR3 TMEM176A EMP3	1.87e-04	186	68	4	8ea708070166c858cd9bd871670655b0114c32a5
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	LGMN FPR3 TMEM176A TPCN1	1.91e-04	187	68	4	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	Control-Endothelial-VE_Capillary_A\|Endothelial / Disease state, Lineage and Cell class	FZD4 MARVELD2 EMP3 CHRM3	1.95e-04	188	68	4	88b3415e33db81726dd29c1f50c886e057af50a0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HLA-A HLA-H TMEM176A NMBR	1.95e-04	188	68	4	0501a8aa850bd2e347020abd1cac4d8075738189
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR61 KCNK10 SLITRK5 NCAM2	1.95e-04	188	68	4	bd091503f580dedab40e0996273101285d24b586
ToppCell	18-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	HTR2C SLC6A17 TMEM176A GOLT1A	1.99e-04	189	68	4	144beb01b908f2cd0e04513fb84d817e0c3c124e
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LGMN CHI3L2 GOLT1A SLC6A14	1.99e-04	189	68	4	da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LGMN FPR3 TMEM176A EMP3	1.99e-04	189	68	4	0a490730cdc912d5233de59057550de0e4065747
ToppCell	wk_20-22-Hematologic_Lymphocytic-NK-CD56bright_NK\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADGRG3 ADRB2 HLA-A CD160	2.03e-04	190	68	4	c8031df82c3662ce4140c850277987f7210e9bcd
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	ADRB2 HLA-A CHI3L2 CD160	2.03e-04	190	68	4	4240d52a465bc3f8016834b22a35c44ba2b0a9f4
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJB6 TMEM176A OTOP3 VAMP8	2.07e-04	191	68	4	7065728128e37572b87e6b024374796bd2172e92
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-Tuft-related\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJB6 TMEM176A OTOP3 VAMP8	2.07e-04	191	68	4	7717cf1d99b4451d7145d91367637895f9a2c1c3
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NWD1 GJB6 GPR37L1 GABBR1	2.07e-04	191	68	4	fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCell	NS-critical-d_0-4\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FPR3 TMEM176A EMP3 VAMP8	2.07e-04	191	68	4	769942a6a31c13c583dc38e8a762df2f5c06c2fb
ToppCell	normal_Pleural_Fluid-T/NK_cells-NK\|normal_Pleural_Fluid / Location, Cell class and cell subclass	ADGRG3 HLA-A SLITRK5 CD160	2.11e-04	192	68	4	59dd4f5ae9f1cca78adf60b71661092ef09e6641
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LGMN FPR3 TMEM176A EMP3	2.11e-04	192	68	4	033e5e61930c28e28a7c64794858f6526e30ff74
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	ADRB2 HLA-A CHI3L2 CD160	2.11e-04	192	68	4	a0bd4a0d00246af4f6645e66a0dedfe36882cc60
ToppCell	IIH-CD8\|IIH / Condition, Cell_class and T cell subcluster	ADRB2 HLA-A CHI3L2 CD160	2.16e-04	193	68	4	343ac8c6dc6d7c7a944a14de65f1d4ea3dfafe86
ToppCell	IIH-CD8-CD8_1\|IIH / Condition, Cell_class and T cell subcluster	ADRB2 HLA-A CHI3L2 CD160	2.16e-04	193	68	4	c5a4926003906d6726155f19061b73fb45d9962c
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADGRG3 ACKR3 FPR3 EMP3	2.16e-04	193	68	4	5703a6faaee82cbad5ce73429bdf1b0f47b37ee0
ToppCell	metastatic_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ADRB2 HLA-A EMP3 CD160	2.20e-04	194	68	4	73c057b623829de793616d9d373a0018071d51d8
ToppCell	MS-CD8\|MS / Condition, Cell_class and T cell subcluster	ADRB2 HLA-A CHI3L2 CD160	2.20e-04	194	68	4	8dfeaa213403cedecb1976bfde1bac84f0155999
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|367C / Donor, Lineage, Cell class and subclass (all cells)	LGMN FPR3 TMEM176A VAMP8	2.20e-04	194	68	4	e3688f4252aae5f849f025d7f453ff4c0c14590b
ToppCell	Monocytes-C1QA+_Monocytes\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LGMN FPR3 TMEM176A VAMP8	2.20e-04	194	68	4	3e104e85574894c04791252d466d438fc809dde3
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LGMN FPR3 ADGRD2 EMP3	2.20e-04	194	68	4	fa50c77a6d6b083cdafdb07243bc68b894977487
ToppCell	AT2\|World / shred by cell class for parenchyma	CHI3L2 VAMP8 GOLT1A SLC6A14	2.20e-04	194	68	4	e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LGMN ATP8A2 CHI3L2 GOLT1A	2.20e-04	194	68	4	46266d3d9af7000dc1381b1c8e55047193cbcf94
ToppCell	CTRL-Myeloid-Monocyte_Macrophage\|CTRL / Disease state, Lineage and Cell class	LGMN FPR3 TMEM176A GABBR1	2.20e-04	194	68	4	927480f56cccd3940b689f3c40ee132fe3e63745
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD8_TEM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ADRB2 HLA-A EMP3 CD160	2.20e-04	194	68	4	fa53f1aab2f5923e90f090e10e3560b583441dc4
ToppCell	MS-CD8-CD8_1\|MS / Condition, Cell_class and T cell subcluster	ADRB2 HLA-A CHI3L2 CD160	2.20e-04	194	68	4	9c05eb30c4b5c6fc410b83cb8aa8138bd46527c9
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LGMN ATP8A2 CHI3L2 GOLT1A	2.20e-04	194	68	4	0db439a544cf8f918a77058fd70319ab0e8e645e
ToppCell	IPF-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	LGMN FPR3 EMP3 VAMP8	2.24e-04	195	68	4	50edda117b438b9c3616191884007466f6d974f0
ToppCell	BLOOD--(1)_T_cell-(1)_EM_CTLs\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ADRB2 HLA-A EMP3 CD160	2.24e-04	195	68	4	7df67ad5c62235474ee56ea07a957253d45f066b
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHI3L2 GOLT1A TMEM87A SLC6A14	2.24e-04	195	68	4	6867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LGMN FPR3 TMEM176A EMP3	2.24e-04	195	68	4	a65441ab3ee1949ec14db1d2d03bb1ee80d389bd
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LGMN FPR3 ADGRD2 EMP3	2.24e-04	195	68	4	ef2304acb01638df197f42dcc3db8c5867f4dc17
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LGMN FPR3 ADGRD2 EMP3	2.24e-04	195	68	4	5ed495941b80221206b8a9a86d92221ab8ba6682
ToppCell	cellseq-Epithelial-Epithelial_Alveolar-AT2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHI3L2 GOLT1A TMEM87A SLC6A14	2.24e-04	195	68	4	955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCell	(3)_MNP-(3)_Macrophage_MARCOneg\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	LGMN FPR3 TMEM176A TPCN1	2.24e-04	195	68	4	e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCell	Macrophages-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	LGMN FPR3 TMEM176A EMP3	2.24e-04	195	68	4	eb104f3bb08ab9eca31273c0523a5c90de1f30a9
ToppCell	critical-Myeloid-Monocyte-derived_DC\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	LGMN FPR3 TMEM176A VAMP8	2.24e-04	195	68	4	599510a5318eef054c117763c9ff86c90957483a
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Cytotoxic_CD8+_T\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ADRB2 HLA-A EMP3 CD160	2.29e-04	196	68	4	6789c88a99cadfd8122ece4b736ba6783ae6e6f5
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-A CHI3L2 FKBP4 CD160	2.29e-04	196	68	4	530ac678d2be035e9e943302d51288cb810b3972
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ACKR3 FPR3 MAP3K20 EMP3	2.29e-04	196	68	4	7dff78ff7b2b333680de1c9ca78190770574d796
ToppCell	NS-moderate-d_16-33-Myeloid-Monocyte-derived_DC\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	LGMN FPR3 TMEM176A VAMP8	2.29e-04	196	68	4	6d056d8336df6b31065be6f7b041bf553fe7c521
ToppCell	metastatic_Lymph_Node-T/NK_cells-NK\|metastatic_Lymph_Node / Location, Cell class and cell subclass	ADGRG3 ADRB2 HLA-A CD160	2.29e-04	196	68	4	f69f53e2ac1818b4ad0161b0bd70655e98ef65f0
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM1\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	LGMN FPR3 TMEM176A TPCN1	2.29e-04	196	68	4	7c8aa5853d7096628e35af665097c0299c329753
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM1-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LGMN FPR3 TMEM176A TPCN1	2.29e-04	196	68	4	f60b220ed117bcc33e0f7bbf5b53d3b1422ebaca
ToppCell	ILEUM-inflamed-(3)_Resident_macrophages\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LGMN FPR3 TMEM176A VAMP8	2.29e-04	196	68	4	5ac246a823a8e1996325753858615269687b429d
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CHI3L2 GOLT1A TMEM87A SLC6A14	2.29e-04	196	68	4	345d4cc062b43bca9d506fbf23363469a9ba496f
Drug	AL-20	PKHD1 HRH4 ETNK1	5.02e-06	12	66	3	CID000002782
Drug	atropine sulfate	ADRB2 ATP7B HTR2C HLA-A HRH4 TACR1 NMBR CHRM3	7.15e-06	347	66	8	CID000003661
Drug	zotepine	ADRB2 HTR2C HRH4 CHRM3	1.24e-05	49	66	4	CID000005736
Drug	NSC186061	ADRB2 HTR2C HRH4 TACR1 CHRM3	2.38e-05	118	66	5	CID000004163
Drug	CID9572793	ADRB2 SLC45A2 TACR1	3.44e-05	22	66	3	CID009572793
Drug	aganodine	ADRB2 HRH4 TACR1	3.95e-05	23	66	3	CID000176878
Drug	linuron	ATP8A2 VAMP8 FKBP4	3.95e-05	23	66	3	CID000009502
Drug	WIN 62577	TACR1 CHRM3	4.95e-05	4	66	2	ctd:C086110
Drug	WIN 51708	TACR1 CHRM3	4.95e-05	4	66	2	ctd:C086111
Drug	4-(1H-imidazol-4-ylmethyl)piperidine	ADRB2 HRH4	4.95e-05	4	66	2	ctd:C085755
Drug	GTP[S]	ADRB2 HTR2C FPR3 KCNK10 HRH4 TACR1 NMBR VAMP3 TPCN1	4.99e-05	591	66	9	CID000001764
Drug	Clozapine	HTR2C HRH4 CHRM3	5.77e-05	26	66	3	DB00363
Drug	tardan	ADRB2 HTR2C CHRM3	5.77e-05	26	66	3	CID000002729
Drug	GMBS	HLA-A NCAM2 FKBP4	6.47e-05	27	66	3	CID000133440
Disease	exercise	DPY19L1 NPSR1	3.21e-04	12	66	2	EFO_0000483
Disease	Hypoxanthine measurement	GPR61 PKHD1	3.78e-04	13	66	2	EFO_0021604
Disease	obesity (is_implicated_in)	ADRB2 HTR2C SLC6A14	1.13e-03	91	66	3	DOID:9970 (is_implicated_in)
Disease	Ventricular Dysfunction, Left	ADRB2 FNDC5	2.06e-03	30	66	2	C0242698
Disease	Hyperkinesia, Generalized	HTR2C GABBR1	2.34e-03	32	66	2	C0751217
Disease	heart conduction disease (implicated_via_orthology)	KCNK10 ETNK1	2.34e-03	32	66	2	DOID:10273 (implicated_via_orthology)
Disease	Hyperkinesia	HTR2C GABBR1	2.34e-03	32	66	2	C3887506
Disease	asthma (is_marker_for)	TACR1 CHRM3 IFNL1	2.86e-03	126	66	3	DOID:2841 (is_marker_for)
Disease	Alcoholic Intoxication, Chronic	HTR2C NPSR1 TACR1 GABBR1	3.08e-03	268	66	4	C0001973
Disease	age at onset, alcohol dependence	ACKR3 NCAM2	4.00e-03	42	66	2	EFO_0004847, MONDO_0007079
Disease	Alcohol Use Disorder	TACR1 GABBR1	4.39e-03	44	66	2	C0001956

Protein segments in the cluster

Peptide	Gene	Start	Entry
CKMWAIGITVLVIFI	VAMP3	76	Q15836
WKNVKMIVLICVIVF	VAMP8	71	Q9BV40
VWVVGMGIVMSLIVL	ADRB2	31	P07550
WIVAVAVILMVLGLL	BTN1A1	246	Q13410
GFLQEKVWVMLVTSL	CD160	161	O95971
MSTLTLVVWIVIGFI	ATP7B	931	P35670
TTKRAGVMIGLAWVI	CHRM3	181	P20309
AIMKIAIVWAISIGV	HTR2C	171	P28335
GMVVLALVVWKIFTL	ADGRG3	446	Q86Y34
MDQKSLWAGVVVLLL	CHI3L2	6	Q15782
MWKEVAVGDIVKVVN	ATP8A2	166	Q9NTI2
ITAMAWGVEEKLLVI	NWD1	871	Q149M9
VVTGAVVAAVMWRKK	HLA-H	321	P01893
LITIMANLGLIAVIW	OR5H8	36	P0DN80
SMGIIIVGGVIWKTI	MFN1	596	Q8IWA4
IEMVFIGVQTWVLWK	OTOP3	201	Q7RTS5
VVTVVGNLGMTTLIW	OR8G1	36	Q15617
WVVSILHTMLRVGLV	OR1B1	151	Q8NGR6
CVKAMGIWVVSVLLA	NMBR	161	P28336
SVLVGVWVKALAMAS	GPR61	161	Q9BZJ8
VWVKALAMASVPVLG	GPR61	166	Q9BZJ8
ISIMYGIVIRTIWIK	NPSR1	226	Q6W5P4
IVINLAVLRWIKGEM	NLRP11	161	P59045
GVWVAKVVFMVLALV	ENTPD8	466	Q5MY95
LLVGMDVLTLAIWQI	GABBR1	716	Q9UBS5
LAKRVMTGLWIFTIV	FPR3	141	P25089
EVWMALVKVLSRAGL	OR2Z1	296	Q8NG97
MSIWVGNVLIMVTVA	OR4Q2	36	P0C623
AIVRKIISDMWGVLA	DPY19L1	421	Q2PZI1
VGAVAAVTMLSWIVA	GDPD5	166	Q8WTR4
GGLQTVMKWKTVVAI	KCNK10	61	P57789
VMKWKTVVAIFVVVV	KCNK10	66	P57789
MISITEWQKIGVGIT	GOLT1A	1	Q6ZVE7
QAIAVTALLWMEIGI	ABCC4	221	O15439
AWAIPAVKTIVILIM	FZD4	351	Q9ULV1
VFKVAIAGAPVTVWM	DPP9	746	Q86TI2
LVVALGILTFIWVLM	FITM2	191	Q8N6M3
QSILAKLAVIWVGSM	GPR37L1	246	O60883
GKVWITVIFIFRVMI	GJB6	21	O95452
MAAAWTVVLVTLVLG	IFNL1	1	Q8IU54
KEWLIGMELVSVVLG	ACKR3	206	P25106
QTVGTKMIWVAVIGD	G6PC2	51	Q9NQR9
VITGAVVAAVMWRRK	HLA-A	321	P04439
VMEKWIVGIAKSQTV	MAP3K20	496	Q9NYL2
GLAWITTIIILVLGM	MARVELD2	261	Q8N4S9
GWLKAVQVLMVLSLI	EMP3	61	P54852
VAVVVVVVSAVAWAM	ETNK1	76	Q9HBU6
VIKAWDIAIATMKVG	FKBP4	86	Q02790
RKLVWAISVTMIGVV	SLC45A2	136	Q9UMX9
HTGVLKIVTLMVAVW	HRH4	126	Q9H3N8
KIVTLMVAVWVLAFL	HRH4	131	Q9H3N8
ASWVMQIVLGILSAV	TMEM176A	56	Q96HP8
LTLLVLGMVWVASAI	LMBR1L	161	Q6UX01
LIIVVVLFMWAGVIA	FNDC5	156	Q8NAU1
SVVGNVVVMWIILAH	TACR1	46	P25103
TVMVSVLEKGWEIVI	PKHD1	3566	P08F94
VLGGTMEWIMIKVRV	SMIM4	31	Q8WVI0
VEGLLLWRKVVAVSM	ADGRD2	741	Q7Z7M1
TIEALRMAGIKVWVL	ATP11B	691	Q9Y2G3
HGLMLVALLLVVVTW	TMEM270	136	Q6UE05
IWKIVRSHGVQTMVV	NCAM2	541	O15394
IVGMKLWVEQLKVGV	SLITRK5	571	O94991
VTEVSQWMVGVKRLI	SRA1	176	Q9HD15
LWMIITSIFLGVITV	TTMP	66	Q5BVD1
VAVNGVWILVETFML	TPCN1	451	Q9ULQ1
WIAAVIFLGMLEKAV	TMEM87B	251	Q96K49
LLVAWSIVGMAVVKG	SLC6A17	231	Q9H1V8
VKWLAVVIMGVVLQG	TVP23B	151	Q9NYZ1
WIPIMAIIKIIQAKG	SLC6A14	576	Q9UN76
WAVLMLLGVVAVVIA	TMEM182	116	Q6ZP80
WIGAVIFLGMLEKAV	TMEM87A	261	Q8NBN3
AVIVVIMGAFLVEAW	TARM1	241	B6A8C7
MVWKVAVFLSVALGI	LGMN	1	Q99538