Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

SETX DNAH10 ATAD5 ZGRF1 SMC1A SMC6 RSF1 CHD2 KIF20B SMARCA1 MACF1 DNAH6 HSPA6

2.74e-0561410813GO:0140657
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

SETX ATAD5 ZGRF1 RSF1 CHD2 SMARCA1

6.62e-051271086GO:0008094
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH10 ATAD5 SMC1A SMC6 RSF1 CHD2 KIF20B MACF1 DNAH6 HSPA6

1.40e-0444110810GO:0016887
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH10 ATAD5 SMC1A SMC6 RSF1 CHD2 KIF20B RABL2B RABL2A GNL2 MACF1 DNAH6 HSPA6

2.82e-0477510813GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH10 ATAD5 SMC1A SMC6 RSF1 CHD2 KIF20B RABL2B RABL2A GNL2 MACF1 DNAH6 HSPA6

5.99e-0483910813GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH10 ATAD5 SMC1A SMC6 RSF1 CHD2 KIF20B RABL2B RABL2A GNL2 MACF1 DNAH6 HSPA6

6.06e-0484010813GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH10 ATAD5 SMC1A SMC6 RSF1 CHD2 KIF20B RABL2B RABL2A GNL2 MACF1 DNAH6 HSPA6

6.06e-0484010813GO:0016818
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

RSF1 CHD2 SMARCA1

1.05e-03371083GO:0140658
DomainSpectrin

SPTB DST MACF1 MCF2L

7.40e-06231044PF00435
DomainSpectrin_repeat

SPTB DST MACF1 MCF2L

1.94e-05291044IPR002017
DomainSpectrin/alpha-actinin

SPTB DST MACF1 MCF2L

2.89e-05321044IPR018159
DomainSPEC

SPTB DST MACF1 MCF2L

2.89e-05321044SM00150
DomainTPR_REGION

DNAH10 P4HA3 IFIT1 IFIT1B TTC12 ASPH ZC3H7B

3.83e-051651047PS50293
DomainTPR

DNAH10 P4HA3 IFIT1 IFIT1B TTC12 ASPH ZC3H7B

3.83e-051651047PS50005
DomainUIM

EPN3 EPN2 ANKRD13A

1.29e-04181043PF02809
DomainUIM

EPN3 EPN2 ANKRD13A

2.07e-04211043SM00726
DomainTPR_8

IFIT1 IFIT1B TTC12 ZC3H7B

2.15e-04531044PF13181
DomainP-loop_NTPase

SETX DNAH10 ATAD5 ZGRF1 SMC1A SMC6 CHD2 HNRNPUL1 KIF20B RABL2B RABL2A GNL2 SMARCA1 DNAH6

2.53e-0484810414IPR027417
Domain-

SETX DNAH10 ATAD5 ZGRF1 SMC1A SMC6 CHD2 HNRNPUL1 RABL2B RABL2A GNL2 SMARCA1 DNAH6

2.55e-04746104133.40.50.300
DomainActinin_actin-bd_CS

SPTB DST MACF1

2.74e-04231043IPR001589
DomainACTININ_2

SPTB DST MACF1

2.74e-04231043PS00020
DomainACTININ_1

SPTB DST MACF1

2.74e-04231043PS00019
DomainUIM

EPN3 EPN2 ANKRD13A

3.12e-04241043PS50330
DomainUIM_dom

EPN3 EPN2 ANKRD13A

3.53e-04251043IPR003903
DomainSANT_dom

MTA3 SMARCA1 SMARCC1

3.97e-04261043IPR017884
Domain-

DST MACF1

4.54e-04610423.90.1290.10
DomainENTH

EPN3 EPN2

4.54e-0461042PF01417
DomainGAR

DST MACF1

4.54e-0461042PS51460
Domain-

DST MACF1

4.54e-04610423.30.920.20
DomainGAS_dom

DST MACF1

4.54e-0461042IPR003108
DomainGAS2

DST MACF1

4.54e-0461042PF02187
DomainGAS2

DST MACF1

4.54e-0461042SM00243
DomainCH

SPTB DST MACF1 CNN2

4.73e-04651044SM00033
DomainSANT

MTA3 SMARCA1 SMARCC1

4.97e-04281043PS51293
DomainCH

SPTB DST MACF1 CNN2

6.27e-04701044PF00307
DomainPlectin_repeat

DST MACF1

6.33e-0471042IPR001101
DomainPlectin

DST MACF1

6.33e-0471042PF00681
DomainPLEC

DST MACF1

6.33e-0471042SM00250
Domain-

SPTB DST MACF1 CNN2

6.62e-047110441.10.418.10
DomainCH

SPTB DST MACF1 CNN2

7.35e-04731044PS50021
DomainTPR

IFIT1 IFIT1B TTC12 ASPH ZC3H7B

7.74e-041291045SM00028
DomainCH-domain

SPTB DST MACF1 CNN2

8.14e-04751044IPR001715
DomainRecF/RecN/SMC_N

SMC1A SMC6

8.41e-0481042IPR003395
DomainSMC_N

SMC1A SMC6

8.41e-0481042PF02463
DomainTPR_repeat

IFIT1 IFIT1B TTC12 ASPH ZC3H7B

8.89e-041331045IPR019734
Domain-

P4HA3 IFIT1 IFIT1B TTC12 ASPH ZC3H7B

1.06e-0320710461.25.40.10
DomainENTH

EPN3 EPN2

1.08e-0391042PS50942
DomainENTH

EPN3 EPN2

1.08e-0391042SM00273
DomainGDS_CDC24_CS

ARHGEF12 PLEKHG1 MCF2L

1.33e-03391043IPR001331
DomainENTH

EPN3 EPN2

1.34e-03101042IPR013809
DomainTPR-contain_dom

IFIT1 IFIT1B TTC12 ASPH ZC3H7B

1.52e-031501045IPR013026
Domain-

PSD MTMR8 ARHGEF12 CIT PLEKHG1 CADPS MCF2L PLCE1

1.54e-0339110482.30.29.30
DomainTPR-like_helical_dom

P4HA3 IFIT1 IFIT1B TTC12 ASPH ZC3H7B

1.94e-032331046IPR011990
DomainPH_dom-like

PSD MTMR8 ARHGEF12 CIT PLEKHG1 CADPS MCF2L PLCE1

2.62e-034261048IPR011993
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH6

2.68e-03141042IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH6

2.68e-03141042IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH6

2.68e-03141042IPR013602
DomainDHC_N2

DNAH10 DNAH6

2.68e-03141042PF08393
DomainMT

DNAH10 DNAH6

2.68e-03141042PF12777
DomainAAA_8

DNAH10 DNAH6

2.68e-03141042PF12780
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH6

2.68e-03141042IPR011704
DomainAAA_5

DNAH10 DNAH6

2.68e-03141042PF07728
DomainSANT

MTA3 SMARCA1 SMARCC1

2.72e-03501043SM00717
DomainSANT/Myb

MTA3 SMARCA1 SMARCC1

3.04e-03521043IPR001005
DomainDHC_fam

DNAH10 DNAH6

3.08e-03151042IPR026983
DomainDynein_heavy_dom

DNAH10 DNAH6

3.08e-03151042IPR004273
DomainDynein_heavy

DNAH10 DNAH6

3.08e-03151042PF03028
DomainARM-like

SETX SIL1 EFR3A IFRD2 TTC12 USP35

4.02e-032701046IPR011989
DomainPH

PSD ARHGEF12 CIT PLEKHG1 CADPS MCF2L

4.63e-032781046SM00233
DomainPH_DOMAIN

PSD ARHGEF12 CIT PLEKHG1 CADPS MCF2L

4.71e-032791046PS50003
DomainPH_domain

PSD ARHGEF12 CIT PLEKHG1 CADPS MCF2L

4.79e-032801046IPR001849
DomainDH_1

ARHGEF12 PLEKHG1 MCF2L

5.23e-03631043PS00741
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

STX8 ELOB ATAD5 UBXN8 SPART SLU7 HNRNPUL1 PLXNB2 DNAJB14 ESF1 STT3B EFR3A PLEKHG1 PTPN2 ASPH GNL2 MACF1 OS9 CTNNA1 HSPA6 QRSL1 CUX1 GOLGA4

1.53e-1014871082333957083
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETX SMC1A RSF1 ACOT7 SLU7 RIOK3 CHD2 VPS16 HNRNPUL1 KIF20B NKRF ESF1 DST ASPH SMARCA1 SF3A3 CSTA SMARCC1 MACF1 HSPA6 GOLGA4 PMM2

1.60e-1013531082229467282
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ELOB SETX ATAD5 ARHGEF12 CHD2 CIT KIF20B NKRF GGCX ESF1 STT3B EPN2 EFR3A DST MTA3 IFRD2 ASPH GNL2 MACF1 OS9 ZC3H7B HSPA6

1.06e-0914971082231527615
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SETX ESS2 ATAD5 SMC1A SMC6 RSF1 CHD2 KIF20B MTA3 GNL2 SMARCA1 SMARCC1 CUX1

5.67e-086081081336089195
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ANXA4 SPTB CHD2 GTF2IRD1 SHTN1 SIL1 SH3YL1 ARHGAP6 FAM111A MTA3 TTC12 ASPH FNIP1 MACF1 OS9 MCF2L TMEM181 CUX1 GOLGA4

1.56e-0714891081928611215
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

EPN3 ANXA4 PDAP1 ARHGEF12 GLOD4 SHTN1 EPN2 EFR3A DST MACF1 CTNNA1 CNN2

2.04e-075651081225468996
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ELOB SETX SMC1A PDAP1 CHD2 HNRNPUL1 GTF2IRD1 NKRF STT3B DST VCAN GNL2 SF3A3 SMARCC1 MACF1 HSPA6

2.40e-0710821081638697112
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SETX ATAD5 SMC1A SMC6 RSF1 PDAP1 SLU7 HNRNPUL1 KIF20B NKRF ESF1 GNL2 SF3A3 SMARCC1 CUX1

2.74e-079541081536373674
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SMC1A SLU7 HNRNPUL1 CIT KIF20B NKRF ESF1 STT3B PTPN2 DST MTA3 ASPH GNL2 SMARCA1 SF3A3 CSTA CTNNA1

3.41e-0712571081736526897
Pubmed

A protein interaction landscape of breast cancer.

AVEN ACOT7 NKRF AREG DST MTA3 SMARCC1 MACF1 OS9 CTNNA1 GSTO1 RGL2

6.89e-076341081234591612
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ELOB ATAD5 RSF1 ACOT7 PDAP1 SPART GLOD4 HNRNPUL1 SHTN1 NKRF ESF1 DST GNL2 MACF1

1.24e-069341081433916271
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPN3 KIAA0513 MTMR8 GTF2IRD1 PLXNB2 CIT TBC1D9 SIL1 TBC1D16 PLEKHG1 DST IFRD2 MCF2L ZC3H7B RGL2

1.71e-0611051081535748872
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNAH10 SPTB ARHGEF12 DST DNAH6 HSPA6 CUX1

2.05e-06187108726460568
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

ELOB SETX SMC1A RSF1 CHD2 NKRF MTA3 SMARCA1 SMARCC1 CTNNA1

2.15e-064691081027634302
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

STX8 ELOB PDAP1 HNRNPUL1 IFIT1 NKRF STT3B ANKRD13A DST ASPH GNL2 SF3A3 CSTA OS9 CTNNA1 HSPA6 CUX1

2.19e-0614401081730833792
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

UBXN8 RSF1 PDAP1 CHD2 TEX14 DNAJB14 ESF1 STT3B PRDM8 DST SMARCA1 SMARCC1 MACF1 MCF2L DNAH6 HSPA6 CUX1

2.23e-0614421081735575683
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

SETX ESS2 KIAA0513 SMC1A ACOT7 SLU7 NKRF TTLL7 SMARCA1 SF3A3 CSTA SMARCC1 CUX1

2.69e-068571081325609649
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMC1A SPTB SPART RIOK3 CHD2 CMYA5 DST MACF1 OS9 PLCE1

3.60e-064971081023414517
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ATAD5 SMC1A SMC6 SLU7 HNRNPUL1 KIF20B NKRF ESF1 ASPH GNL2 MACF1 ZC3H7B

4.41e-067591081235915203
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ANXA4 ACOT7 PDAP1 SPART GLOD4 HNRNPUL1 PLXNB2 IFIT1 DNAJB14 ANKRD13A PTPN2 SF3A3 SMARCC1 CTNNA1 CNN2 PMM2

5.02e-0613671081632687490
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIAA0513 ARHGEF12 PLEKHG1 CADPS FNIP1 MACF1 MCF2L TMEM181 PLCE1

5.31e-06407108912693553
Pubmed

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo.

IFIT1 IFIT1B

9.55e-062108222589727
Pubmed

Mouse Ifit1b is a cap1-RNA-binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c.

IFIT1 IFIT1B

9.55e-062108233454014
Pubmed

Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons.

SHTN1 KIF20B

9.55e-062108223864681
Pubmed

Interaction between p230 and MACF1 is associated with transport of a glycosyl phosphatidyl inositol-anchored protein from the Golgi to the cell periphery.

MACF1 GOLGA4

9.55e-062108215265687
Pubmed

RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State.

RABL2B RABL2A

9.55e-062108227732084
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

9.55e-062108211002341
Pubmed

Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.

DNAH10 DNAH6

9.55e-062108215937072
Pubmed

Overexpression of IFIT1 protects against LPS-induced acute lung injury via regulating CCL5-p65NF-κB signaling.

IFIT1 IFIT1B

9.55e-062108236446235
Pubmed

Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.

RABL2B RABL2A

9.55e-062108220138207
Pubmed

Identification and validation of Ifit1 as an important innate immune bottleneck.

IFIT1 IFIT1B

9.55e-062108222745654
Pubmed

Ifit1 inhibits Japanese encephalitis virus replication through binding to 5' capped 2'-O unmethylated RNA.

IFIT1 IFIT1B

9.55e-062108223824812
Pubmed

The association between expression of IFIT1 in podocytes of MRL/lpr mice and the renal pathological changes it causes: An animal study.

IFIT1 IFIT1B

9.55e-062108227823966
Pubmed

A viral RNA structural element alters host recognition of nonself RNA.

IFIT1 IFIT1B

9.55e-062108224482115
Pubmed

Two novel human RAB genes with near identical sequence each map to a telomere-associated region: the subtelomeric region of 22q13.3 and the ancestral telomere band 2q13.

RABL2B RABL2A

9.55e-062108210444334
Pubmed

Variants in RABL2A causing male infertility and ciliopathy.

RABL2B RABL2A

9.55e-062108233075816
Pubmed

Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA.

IFIT1 IFIT1B

9.55e-062108224098121
Pubmed

Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals.

IFIT1 IFIT1B

9.55e-062108227240734
Pubmed

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon.

IFIT1 IFIT1B

9.55e-062108225927359
Pubmed

IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages.

IFIT1 IFIT1B

9.55e-062108230282041
Pubmed

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families.

IFIT1 IFIT1B

9.55e-062108226157117
Pubmed

Brain-specific ablation of Efr3a promotes adult hippocampal neurogenesis via the brain-derived neurotrophic factor pathway.

BDNF EFR3A

9.55e-062108228193719
Pubmed

RABL2 positively controls localization of GPCRs in mammalian primary cilia.

RABL2B RABL2A

9.55e-062108230578315
Pubmed

Ifit1 Protects Against Lipopolysaccharide and D-galactosamine-Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway.

IFIT1 IFIT1B

9.55e-062108226459629
Pubmed

Postnatal gene expression in the normal mouse cornea by SAGE.

IFIT1 PTPN2 IFIT1B

1.03e-0514108314744882
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ELOB SETX ATAD5 SMC1A CHD2 HNRNPUL1 GTF2IRD1 NKRF STT3B DST ASPH SF3A3 SMARCC1 HSPA6 CUX1

1.14e-0512941081530804502
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

PDAP1 SPART SHTN1 GGCX STT3B PTPN2 DST CNN2 CUX1 GOLGA4

1.15e-055681081037774976
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

ELOB SETX ATAD5 SMC6 HNRNPUL1 GTF2IRD1 KIF20B FAM111A SMARCC1

1.25e-05453108929656893
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

SMC1A PDAP1 ARHGEF12 SPART SHTN1 STT3B EFR3A DST MACF1 CTNNA1 GOLGA4

1.33e-057081081139231216
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

ATAD5 SMC1A SLU7 NKRF MTA3 GNL2 SMARCA1 SF3A3 SMARCC1 CUX1

1.98e-056051081028977666
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

STX8 AVEN SETX ANXA4 CHD2 NKRF GGCX FAM111A AFP ASPH GNL2 SMARCA1 CSTA SMARCC1 CNN2

2.25e-0513711081536244648
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

ELOB ESS2 SMC1A ARHGEF12 GLOD4 PLEKHG1 ARHGAP6 CSTA SMARCC1 CTNNA1 MCF2L GOLGA4

2.85e-059161081232203420
Pubmed

Structure, chromosome localization, and regulation of expression of the interferon-regulated mouse Ifi54/Ifi56 gene family.

IFIT1 IFIT1B

2.86e-05310827896268
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

2.86e-053108212399109
Pubmed

Isolation of a gene expressed during early embryogenesis from the region of 22q11 commonly deleted in DiGeorge syndrome.

ESS2 AFP

2.86e-05310828268909
Pubmed

The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins.

IFIT1 IFIT1B

2.86e-053108230232164
Pubmed

Mouse p56 blocks a distinct function of eukaryotic initiation factor 3 in translation initiation.

IFIT1 IFIT1B

2.86e-053108215561726
Pubmed

Novel characteristics of the function and induction of murine p56 family proteins.

IFIT1 IFIT1B

2.86e-053108218768971
Pubmed

Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) accelerates osteoclast formation by regulating signal transducer and activator of transcription 3 (STAT3) signalling.

IFIT1 IFIT1B

2.86e-053108235034537
Pubmed

The interaction between interferon-induced protein with tetratricopeptide repeats-1 and eukaryotic elongation factor-1A.

IFIT1 IFIT1B

2.86e-053108219856081
Pubmed

Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.

ARHGEF12 PLXNB2

2.86e-053108226627240
Pubmed

Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner.

SMARCC1 CTNNA1 CUX1

3.19e-0520108334220450
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNAH10 SMC1A SMC6 GLOD4 HNRNPUL1 CMYA5 ESF1 STT3B GBA3 GNL2 SMARCA1 SF3A3 CSTA SMARCC1 GOLGA4

3.50e-0514251081530948266
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RSF1 CHD2 HNRNPUL1 NKRF ESF1 DST GNL2 SMARCC1 MACF1 CTNNA1

3.78e-056531081022586326
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

ELOB SPART SLU7 CIT GGCX SIL1 OS9

4.21e-05298108732353859
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

SMC1A RSF1 KIF20B MTA3 SMARCA1 SF3A3 SMARCC1 HSPA6

4.47e-05411108835182466
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SMC1A SPTB SYNC HNRNPUL1 CMYA5 SHTN1 CIT SH3YL1 DST MTA3 CADPS MACF1 CTNNA1 CUX1

4.52e-0512851081435914814
Pubmed

Endoglin haploinsufficiency promotes fibroblast accumulation during wound healing through Akt activation.

SHTN1 KIF20B

5.71e-054108223349951
Pubmed

Interferon-induced protein Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus.

IFIT1 IFIT1B

5.71e-054108224991014
Pubmed

Ifit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages.

IFIT1 IFIT1B

5.71e-054108224198415
Pubmed

Attenuation and restoration of severe acute respiratory syndrome coronavirus mutant lacking 2'-o-methyltransferase activity.

IFIT1 IFIT1B

5.71e-054108224478444
Pubmed

Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses.

IFIT1 IFIT1B

5.71e-054108217079283
Pubmed

Interferon-induced Ifit proteins: their role in viral pathogenesis.

IFIT1 IFIT1B

5.71e-054108225428874
Pubmed

The glucocorticoid attenuated response genes GARG-16, GARG-39, and GARG-49/IRG2 encode inducible proteins containing multiple tetratricopeptide repeat domains.

IFIT1 IFIT1B

5.71e-05410828660659
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1

5.71e-05410828954775
Pubmed

Megabase deletions of gene deserts result in viable mice.

KIF20B TTLL7

5.71e-054108215496924
Pubmed

Tissue-specific and inducer-specific differential induction of ISG56 and ISG54 in mice.

IFIT1 IFIT1B

5.71e-054108217553874
Pubmed

Sendai virus pathogenesis in mice is prevented by Ifit2 and exacerbated by interferon.

IFIT1 IFIT1B

5.71e-054108225231314
Pubmed

The epsin family of endocytic adaptors promotes fibrosarcoma migration and invasion.

EPN3 EPN2

5.71e-054108220709745
Pubmed

Lysyl oxidase-like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3.

IFIT1 IFIT1B

5.71e-054108237496288
Pubmed

Genome-wide ENU mutagenesis to reveal immune regulators.

RABL2B RABL2A

5.71e-054108211567631
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH10 DNAH6

5.71e-054108211175280
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

AVEN SETX ARHGEF12 BDNF DST GSTO1 PMM2

5.74e-05313108720800603
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

ELOB SMC1A ACOT7 PDAP1 SPART HNRNPUL1 SHTN1 ESF1 DST SF3A3 MACF1 GSTO1 HSPA6

5.89e-0511491081335446349
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

ELOB ATAD5 ANXA4 SMC1A SMC6 RSF1 CHD2 NKRF ESF1 PTPN2 MTA3 SMARCC1

7.56e-0510141081232416067
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

CHD2 IFIT1 NKRF FAM111A ASPH SMARCA1

8.15e-05228108630471916
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

ESS2 PDAP1 SLU7 NKRF DST GNL2 SF3A3 CTNNA1 ZC3H7B GOLGA4

8.80e-057231081034133714
Pubmed

Rabl2 GTP hydrolysis licenses BBSome-mediated export to fine-tune ciliary signaling.

RABL2B RABL2A

9.50e-055108233241915
Pubmed

The protective role of Toll-like receptor 3 and type-I interferons in the pathophysiology of vein graft disease.

IFIT1 IFIT1B

9.50e-055108229879406
Pubmed

Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members.

IFIT1 IFIT1B

9.50e-055108227137933
Pubmed

Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.

ARHGEF12 PLXNB2

9.50e-055108212183458
Pubmed

A molecular network for the transport of the TI-VAMP/VAMP7 vesicles from cell center to periphery.

MACF1 GOLGA4

9.50e-055108222705394
Pubmed

Ifit2 Is a Restriction Factor in Rabies Virus Pathogenicity.

IFIT1 IFIT1B

9.50e-055108228637751
Pubmed

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis.

IFIT1 IFIT1B

9.50e-055108222615570
Pubmed

Functional proteomics mapping of a human signaling pathway.

EPN3 SPART HNRNPUL1 SIL1 EPN2 ANKRD13A DST MACF1 OS9

9.78e-05591108915231748
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

ZGRF1 ANXA4 SPTB CHD2 PLXNB2 TBC1D9 TBC1D16 FAM228B RABL2A VCAN OS9 USP35 GSTO1

1.03e-0412151081315146197
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

STX8 UBXN8 STT3B EPN2 EFR3A MACF1 CTNNA1 CUX1

1.09e-04467108830194290
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ELOB SPART SLU7 CIT GGCX SIL1 STT3B GNL2 OS9 CUX1

1.24e-047541081033060197
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

ELOB SMC1A PDAP1 GLOD4 HNRNPUL1 ASPH GNL2 SF3A3 SMARCC1 MACF1 CTNNA1 HSPA6 CNN2 GOLGA4

1.25e-0414151081428515276
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

ELOB SETX SMC1A HNRNPUL1 NKRF ASPH GNL2 SMARCA1 SMARCC1

1.32e-04615108931048545
InteractionCIT interactions

SETX SMC1A SPTB RSF1 CHD2 HNRNPUL1 CMYA5 CIT NKRF ESF1 FAM228B MTA3 ASPH GNL2 SMARCA1 SF3A3 SMARCC1 MACF1 CTNNA1 HSPA6 CNN2 CUX1 GOLGA4

2.07e-06145010823int:CIT
InteractionH3C3 interactions

SETX ESS2 ATAD5 SMC1A SMC6 RSF1 KIF20B MTA3 GNL2 SMARCA1 SMARCC1 CUX1

1.39e-0549510812int:H3C3
Cytoband10q23.31

IFIT1 KIF20B IFIT1B

7.18e-0534108310q23.31
GeneFamilyRAB like GTPases

RABL2B RABL2A

1.23e-045642394
GeneFamilyStructural maintenance of chromosomes proteins|Cohesin complex

SMC1A SMC6

2.56e-047642761
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

3.41e-048642939
GeneFamilyUPF1 like RNA helicases

SETX ZGRF1

6.65e-04116421169
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

IFIT1 IFIT1B TTC12 ZC3H7B

7.35e-04115644769
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PSD SPTB PLEKHG1 CADPS MCF2L

8.08e-04206645682
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MTA3 SMARCA1 SMARCC1

8.73e-0453643532
GeneFamilyDyneins, axonemal

DNAH10 DNAH6

1.62e-0317642536
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF12 PLEKHG1 MCF2L

1.65e-0366643722
CoexpressionBLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP

ESS2 SMC1A CHD2 SYNC HNRNPUL1 PLXNB2 GGCX VCAN SMARCC1 OS9 ZC3H7B GOLGA4

6.73e-0838910712M6520
CoexpressionLIM_MAMMARY_LUMINAL_PROGENITOR_DN

TBC1D9 DST ASPH CUX1

2.55e-07141074M2576
CoexpressionLIM_MAMMARY_LUMINAL_PROGENITOR_DN

TBC1D9 DST ASPH CUX1

2.55e-07141074MM961
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

SETX SMC6 RSF1 SLU7 SHTN1 DNAJB14 KIF20B TBC1D9 ESF1 TTLL7 FAM111A GOLGA4 ENOX2

2.82e-0665610713M18979
CoexpressionGSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

SETX SMC6 CHD2 IFIT1 EFR3A MTA3 CNN2

1.86e-052001077M9164
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SETX SPART KIF20B BDNF EFR3A PTPN2 DST SMARCA1 MACF1 CUX1 GOLGA4 PLCE1 PMM2

4.69e-0585610713M4500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

ATAD5 ZGRF1 SMC1A SMC6 PDAP1 ARHGEF12 SLU7 CHD2 HNRNPUL1 GTF2IRD1 CIT KIF20B NKRF ESF1 EPN2 PTPN2 GNL2 MACF1

2.07e-0962910618Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

ATAD5 SMC1A SMC6 PDAP1 CHD2 GTF2IRD1 CIT KIF20B NKRF ESF1 CUX1 GOLGA4

5.08e-0831110612Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

ATAD5 SMC1A SMC6 PDAP1 SEC11C GTF2IRD1 CIT KIF20B NKRF ESF1 GNL2 MACF1

1.69e-0643210612Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

DNAH10 ATAD5 SMC1A SMC6 PDAP1 ARHGEF12 SEC11C GTF2IRD1 CIT KIF20B NKRF ESF1 EFR3A SH3RF2 GNL2 MACF1 RGL2 TMEM181

1.82e-0698910618Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

ATAD5 SMC1A SMC6 PDAP1 CHD2 GTF2IRD1 PLXNB2 CIT KIF20B NKRF ESF1 RABL2A FNIP1 CUX1 GOLGA4 PMM2

3.59e-0683110616Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

SETX ATAD5 SMC1A RSF1 PDAP1 CIT KIF20B NKRF ESF1 DST GNL2 SMARCC1

3.94e-0646910612Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ATAD5 SMC1A SMC6 PDAP1 CIT KIF20B ESF1 GOLGA4

5.47e-061921068Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4

SMC1A PDAP1 ARHGEF12 CIT KIF20B GNL2 MACF1 TMEM181

5.47e-061921068Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4

ATAD5 SMC1A ARHGEF12 HNRNPUL1 GTF2IRD1 PTPN2 GNL2 MACF1

8.23e-062031068Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

SETX ATAD5 SMC6 RSF1 PDAP1 CIT KIF20B NKRF ESF1 FAM111A SMARCC1 QRSL1

1.40e-0553210612Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2

ATAD5 ZGRF1 SMC1A SLU7 CHD2 HNRNPUL1 GTF2IRD1 ESF1 EPN2 PTPN2 GNL2 MACF1

2.50e-0556410612Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

SMC1A PDAP1 ARHGEF12 CHD2 PLXNB2 CIT KIF20B RABL2A GNL2 SMARCA1 FNIP1 MACF1 CUX1 PMM2

3.35e-0578010614Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

SMC1A SEC11C HNRNPUL1 GTF2IRD1 EFR3A GNL2 MACF1

4.01e-051851067Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K3
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500

RNF34 SHTN1 SIL1 ANKRD13A DST CADPS VCAN SMARCA1 ZC3H7B PLCE1

7.27e-0544110610gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5

ATAD5 RSF1 CIT KIF20B NKRF ESF1 QRSL1

7.44e-052041067Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

ATAD5 SMC1A SMC6 PDAP1 CHD2 GTF2IRD1 CIT KIF20B NKRF ESF1 RABL2A IFRD2 TMEM181 CUX1 GOLGA4

1.16e-0498910615Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500

SMC1A PDAP1 ARHGEF12 P4HA3 GTF2IRD1 CIT KIF20B GNL2 MACF1 TMEM181

1.78e-0449210610Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

ZGRF1 SMC1A ARHGEF12 SLU7 CHD2 HNRNPUL1 ESF1 EPN2 GNL2 MACF1 GOLGA4

1.91e-0459510611Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000

SETX ATAD5 DNAJB14 BDNF TTLL7 EFR3A ARHGAP6 FAM111A VCAN ASPH SMARCA1 FNIP1 CUX1

2.40e-0482610613DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

SETX SMC6 PDAP1 KIF20B SF3A3 SMARCC1 CUX1 GOLGA4

3.02e-043391068gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000

ATAD5 SMC1A ARHGEF12 RIOK3 SEC11C HNRNPUL1 GTF2IRD1 EFR3A PTPN2 IFRD2 GNL2 MACF1 RGL2 TMEM181

3.78e-0498310614Facebase_RNAseq_e9.5_Mandibular Arch_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_500_k-means-cluster#4

ATAD5 RSF1 NKRF ESF1 QRSL1

3.96e-041241065Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_500_K4
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_1000

ANXA4 RNF34 SHTN1 SIL1 ANKRD13A DST MTA3 CADPS VCAN SMARCA1 OS9 ZC3H7B PLCE1

4.59e-0488410613gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

SETX ATAD5 SMC1A SMC6 RSF1 PDAP1 P4HA3 CIT KIF20B NKRF ESF1 VCAN KCNJ15 ASPH GNL2 SMARCC1

4.71e-04125210616facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

SETX ATAD5 ZGRF1 SMC1A SMC6 RSF1 PDAP1 CIT KIF20B NKRF ESF1 KCNJ15 GNL2 SMARCC1 MACF1 CUX1

4.92e-04125710616facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MACF1 CTNNA1 MCF2L RGL2

3.19e-08200108872ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MACF1 CTNNA1 MCF2L RGL2

3.19e-0820010885c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D CMYA5 GTF2IRD1 ARHGAP6 KCNJ15 CUX1 GOLGA4

4.64e-0719310873866667dd221612589ae50f5c52f73a183a49ce6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D TTLL7 DST CADPS FNIP1 MACF1 GOLGA4

4.97e-0719510873e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D TTLL7 DST CADPS FNIP1 MACF1 GOLGA4

4.97e-0719510877796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellLPS_only-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGEF12 IFIT1 DST MACF1 CTNNA1 MCF2L RGL2

5.89e-07200108781e76508c9050d533853d5fd2f3097b27613d836
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MACF1 CTNNA1 RGL2

5.89e-07200108779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / Treatment groups by lineage, cell group, cell type

ARHGEF12 IFIT1 DST MACF1 CTNNA1 MCF2L RGL2

5.89e-0720010874bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETX RSF1 HNRNPUL1 SMARCC1 MACF1 GOLGA4

5.84e-0618410861154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 SHTN1 TBC1D9 PLEKHG1 DST AFP

6.21e-061861086f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCelldroplet-Lung-nan-21m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 SHTN1 TBC1D9 PLEKHG1 DST AFP

6.21e-0618610868f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GTF2IRD1 BDNF TTLL7 DST SH3RF2 PLCE1

6.40e-061871086d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANXA4 SHTN1 TBC1D9 PLEKHG1 DST AFP

6.81e-06189108698f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D CMYA5 GTF2IRD1 ARHGAP6 KCNJ15 CUX1

7.67e-06193108682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHTN1 BDNF TTLL7 DST SH3RF2 PLCE1

8.14e-061951086a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHTN1 BDNF TTLL7 DST SH3RF2 PLCE1

8.62e-0619710868d5097898dd01cedb04cb694cb480c931e08462c
ToppCellVE-mDC2-|VE / Condition, Cell_class and T cell subcluster

GTF2IRD1 SHTN1 AREG TBC1D9 DST CSTA

8.62e-0619710866629588819ec31a7e4f33b94b8c035145a5f6c17
ToppCellVE-mDC2|VE / Condition, Cell_class and T cell subcluster

GTF2IRD1 SHTN1 AREG TBC1D9 DST CSTA

8.62e-061971086e3172102ad17c92c3038cad37bf933eb04351048
ToppCellsevere-Myeloid-CD14_Monocytes_3|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SHTN1 PLXNB2 VCAN CSTA CTNNA1 GSTO1

8.87e-061981086374d7a24e00cd3f435ca980123ab3c6a441c9ad5
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SHTN1 PLXNB2 VCAN CSTA CTNNA1 GSTO1

8.87e-061981086f3346c26b9647a199faf3cd7ab19c3a963dbabc2
ToppCellPSB-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CMYA5 DST ASPH SMARCA1 CSTA CNN2

9.13e-0619910862add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCellcontrol-Myeloid-CD14_Monocytes_1|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TEX14 SHTN1 PLXNB2 VCAN CSTA GSTO1

9.13e-0619910868c14237c3da91d1a4878df489a495408a1e83883
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MACF1 MCF2L

9.40e-062001086dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ARHGEF12 IFIT1 MACF1 CTNNA1 MCF2L RGL2

9.40e-0620010862d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellControl_saline-Endothelial-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MCF2L RGL2

9.40e-062001086e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MACF1 MCF2L

9.40e-062001086a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellLPS_anti-TNF-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MCF2L RGL2

9.40e-0620010861d105eeda5a2c51f9a4654ffc79b7e2348ad593b
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MCF2L RGL2

9.40e-062001086b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCellLPS_anti-TNF-Endothelial-Endothelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MCF2L RGL2

9.40e-06200108660d2cbf41f37f1b11eddb4c9d9246c9c1fc5a5af
ToppCellmild-Myeloid-CD14_Monocytes_1|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TEX14 SHTN1 PLXNB2 VCAN CSTA GSTO1

9.40e-0620010863874c1f078cb8789be2e2275a202357c711b1be3
ToppCellControl_saline-Endothelial|Control_saline / Treatment groups by lineage, cell group, cell type

SETX ARHGEF12 IFIT1 DST MCF2L RGL2

9.40e-0620010863372c488a39fe812fa94e4f0564594186fea3db5
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 TBC1D9 PLEKHG1 USP35 PLCE1

3.05e-0514810856ffa212f0cc44c40d2143816dc6cfd82fbf09a33
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DNAH10 UBXN8 SHTN1 AREG DST

3.58e-05153108591e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAH10 UBXN8 SHTN1 AREG DST

3.58e-051531085f17f62646633cf95c810dcd5328978058741b276
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 CIT ARHGAP6 FAM228B SMARCA1

3.69e-0515410852d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMYA5 CIT ARHGAP6 FAM228B SMARCA1

3.69e-0515410850dec222101530f1727184dbb7c03969d3884f111
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

GTF2IRD1 TTLL7 AFP MCF2L PLCE1

5.13e-0516510853d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AREG VCAN CSTA HSPA6 CNN2

5.43e-0516710851cd9e2af85c6c5b9e1d88991c87ac6980b387243
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC11C SHTN1 CIT KIF20B FAM111A

5.59e-05168108552fd65024af8683db11d931f7563cbe8eb815d1c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

SYNC CMYA5 TTC12 DNAH6 NEK11

6.08e-05171108574be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPN3 CACNA1D ANXA4 MTMR8 SH3RF2

6.08e-051711085f2b31c97bbcc5164fc279ed0362007878887ad5e
ToppCelldroplet-Marrow-nan-24m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 SHTN1 PLXNB2 VCAN GSTO1

6.96e-051761085eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ACOT7 TBC1D16 ASPH RGL2 DNAH6

6.96e-051761085bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHTN1 PLXNB2 AREG DST CSTA

7.74e-0518010852bc3fd2e4c249bf236340c5f0483747faa5c04ec
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHTN1 PLXNB2 AREG DST CSTA

7.95e-0518110851b4eb044825ede6361928442524b1988c8ef58b3
ToppCelldroplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 SHTN1 TBC1D9 DST AFP

7.95e-0518110858fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Dendritic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHTN1 PLXNB2 AREG DST CSTA

7.95e-0518110858d7ebbedc373d55e29da02ac2728b4f4118038f2
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 SHTN1 TBC1D9 DST AFP

8.16e-051821085be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCellCOVID-19_Convalescent-Myeloid-cDC|COVID-19_Convalescent / Disease group, lineage and cell class

SHTN1 AREG TBC1D9 DST CSTA

8.59e-051841085ad6e910eaebe841a68a5f2f329d43dafc5db158a
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SHTN1 AREG TBC1D9 DST CSTA

8.59e-0518410859d678b24532b7763f2e73f7ccb496259977c5204
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SHTN1 AREG TBC1D9 DST CSTA

8.59e-051841085383374ad17bd322b8d703a22e475d34ca7b2e6b6
ToppCellPBMC-Convalescent-Myeloid-cDC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

SHTN1 AREG TBC1D9 DST CSTA

8.59e-0518410855535b85b3ad3d0c0392d5884fdc2939c7e1b1c3e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

BDNF TTLL7 DST SH3RF2 PLCE1

8.59e-051841085561592edc3083fad41b91811151b442207c65dd9
ToppCellPBMC-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-051851085d685a5a2e525db2eba449cfa1e5cd54eb36162a8
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

BDNF TTLL7 DST SH3RF2 PLCE1

8.81e-0518510851c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellPBMC-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-0518510855d8d6fd7800f76ee3aa5cef95241d8e6d7e8db04
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-051851085100b5afdf3c6ab07ffc493f7883f5a7b31c59184
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

BDNF TTLL7 DST SH3RF2 PLCE1

8.81e-05185108532b4e68e551d435a732f253f6ad83408c759a642
ToppCellCOVID-19_Severe-Hematopoietic_R|COVID-19_Severe / Disease group, lineage and cell class

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-05185108530f064ab7c3890e6f419a845276b145112e78f52
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-051851085f3b1907c3b6f930bc161f46efce5e143babab507
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-05185108544ce50cb99df8ffc50eba311adcf688477618659
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANXA4 SHTN1 TBC1D9 AFP ASPH

8.81e-0518510854bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCellPBMC-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-05185108517542ccd52a821c9e99b1a7469e80502e764b3fd
ToppCellCOVID-19_Severe-Hematopoietic_R-RBC|COVID-19_Severe / Disease group, lineage and cell class

ELOB SPTB ARHGEF12 RIOK3 IFIT1B

8.81e-0518510853ed6090b822c6d1d400a421236cddc7511743932
ToppCelldroplet-Tongue-nan-24m-Epithelial-parabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC11C TTLL7 PLEKHG1 TTC12 USP35

9.04e-05186108518c06041c6c8a0ebac17b3c8aaebd67e652d315a
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 SHTN1 TBC1D9 DST AFP

9.27e-051871085f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 SHTN1 TBC1D9 DST AFP

9.27e-051871085f20e7a1751694390f535ffb27b97e887220f8695
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

BDNF TTLL7 DST SH3RF2 PLCE1

9.27e-05187108577f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ANXA4 BDNF SH3RF2 GSTO1 CNN2

9.27e-051871085a4b41904ba05eb76212c949fc3ac197f906c8351
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GTF2IRD1 AREG ANKRD13A SH3RF2 ASPH

9.50e-05188108543a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellfacs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 ACOT7 ANKRD13A SMARCC1 GSTO1

9.74e-051891085533685a921a65d84107d8d33c43b4fffde019143
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANXA4 SHTN1 TBC1D9 PLEKHG1 DST

9.74e-051891085f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-classical_monocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SHTN1 IFIT1 VCAN CSTA GSTO1

9.74e-051891085cce6602ad68c177985a5e43cfb2776d615cfbca0
ToppCellfacs-Marrow-KLS-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 ACOT7 ANKRD13A SMARCC1 GSTO1

9.74e-051891085dca56ab02bf0505f9a352ff907edaef30906d854
ToppCell3'_v3-GI_small-bowel-Myeloid_Monocytic-Classical_monocytes|GI_small-bowel / Manually curated celltypes from each tissue

SHTN1 VCAN KCNJ15 ASPH CSTA

9.74e-05189108574a5e61cd820f2495dde40e766c771a31d8c4e7d
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH10 RABL2B RABL2A DNAH6 NEK11

9.74e-0518910853e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

BDNF TTLL7 DST SH3RF2 PLCE1

9.74e-0518910855a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellfacs-Marrow-KLS-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA4 ACOT7 ANKRD13A SMARCC1 GSTO1

9.99e-051901085a513c1e7df62c28128c932a68b252ee8f0255172
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHTN1 PLXNB2 IFIT1 VCAN CSTA

9.99e-051901085e1c02fe6fa43a36381cb9f02569fa9b1c5f5efdc
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF12 BDNF DST MACF1 GOLGA4

9.99e-051901085d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHTN1 PLXNB2 VCAN CSTA HSPA6

9.99e-0519010854b9bac17eb7ceadada932f2d4a20a5f176088d53
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHTN1 PLXNB2 IFIT1 VCAN CSTA

9.99e-0519010856de15ec88426fbf52acb0a8371f82cf03b6a6237
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATAD5 ZGRF1 CIT KIF20B HSPA6

1.02e-041911085bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SHTN1 PLXNB2 IFIT1 VCAN CSTA

1.02e-04191108581f77bf497b8e0ae0affe7d5f4f00446547229f6
ToppCellCOVID-19-Myeloid-TRAM1|COVID-19 / Condition, Lineage and Cell class

ACOT7 TEX14 ARHGAP6 DST CSTA

1.05e-04192108552b8578699325b0d35a2d3ba36772096130ccc0c
ToppCellNS-critical-d_0-4-Epithelial-Basal|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATAD5 CMYA5 CIT TBC1D16 ANKRD13A

1.07e-0419310851affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCellCOVID-19-Myeloid-TRAM1|Myeloid / Condition, Lineage and Cell class

ACOT7 TEX14 ARHGAP6 DST CSTA

1.07e-0419310856e6a7f4e50c8ae70bc187b9ce77140a7049dd288
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH10 RABL2B RABL2A DNAH6 NEK11

1.07e-041931085ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ARHGAP6 DST VCAN MACF1

1.10e-041941085b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANXA4 SMC6 TBC1D9 PLEKHG1 PLCE1

1.10e-0419410852b5eee7c3e52b63cce94205d18133c7704329c02
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANXA4 CMYA5 GTF2IRD1 ARHGAP6 KCNJ15

1.10e-0419410857002937e8903e037332a215d00fbc7c7843b33f2
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF12 IFIT1 PLEKHG1 DST MCF2L

1.10e-04194108543f92b0533e26633dc94cce554045d641ef8fd76
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AREG VCAN KCNJ15 CSTA GSTO1

1.10e-04194108512e42433a7b7c17c46049ef450223daf2976a59a
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF12 PLEKHG1 DST MACF1 MCF2L

1.10e-0419410850b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF12 IFIT1 PLEKHG1 DST MCF2L

1.10e-0419410851d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AREG VCAN KCNJ15 CSTA GSTO1

1.10e-041941085b191851b2287afc8c47320f5488fd22e2a454aa6
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-late_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SPTB ARHGEF12 RIOK3 P4HA3 IFIT1B

1.10e-04194108523b06707d21306b4483d64cb350b86aef352ce38
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLXNB2 IFIT1 VCAN CSTA HSPA6

1.13e-04195108519413dc6aa0010686cdfa0c750ef0a7a76caf308
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATAD5 ZGRF1 SMC1A CIT KIF20B

1.13e-041951085cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_macrophage|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ELOB PLXNB2 VCAN CSTA GSTO1

1.13e-0419510854e9513a7ea69fa9fc8e9ff2da8ef3f44e8fdc70d
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

ATAD5 SMC1A DST MACF1 GOLGA4

1.83e-0550715GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Diseaseopen-angle glaucoma

ARHGEF12 DST GNL2 TMEM181 PLCE1 PMM2

5.78e-051911036EFO_0004190
Diseasecortical surface area measurement

STX8 ARHGEF12 SYNC SHTN1 PLXNB2 KIF20B TBC1D16 PLEKHG1 CADPS VCAN MACF1 USP35 CUX1 PLCE1

2.42e-04134510314EFO_0010736
DiseaseAtaxias, Hereditary

SETX SIL1

3.33e-0481032C0004138
DiseaseAntihypertensive use measurement

CACNA1D RIOK3 AREG PLEKHG1 PRDM8 PLCE1

3.42e-042651036EFO_0009927
DiseaseImmature Reticulocyte Fraction Measurement

RIOK3 IFRD2

5.33e-04101032EFO_0009253
Diseaseocular hypertension, response to triamcinolone acetonide

RIOK3 TEX14 KIF20B

6.77e-04491033EFO_0006954, EFO_1001069
DiseaseADHD symptom measurement

ARHGEF12 CUX1

7.78e-04121032EFO_0007860
Diseasecoronary artery disease

DNAH10 ARHGEF12 CHD2 HNRNPUL1 BDNF GGCX PLEKHG1 PRDM8 GPR149 SF3A3 MCF2L PLCE1

9.39e-04119410312EFO_0001645
DiseaseTobacco Dependence

BDNF PLEKHG1

1.07e-03141032C0040332
DiseaseNicotine Dependence

BDNF PLEKHG1

1.07e-03141032C0028043
DiseaseNicotine Use Disorder

BDNF PLEKHG1

1.07e-03141032C0376384
Diseasebody weights and measures, body height

ATAD5 RIOK3

1.23e-03151032EFO_0004324, EFO_0004339
Diseasealcohol consumption measurement

CACNA1D RIOK3 P4HA3 CIT BDNF SIL1 STT3B CADPS TTC12 CTNNA1 ZC3H7B CUX1

1.31e-03124210312EFO_0007878
Diseasepreeclampsia, hypertension, pregnancy-induced

PRDM8 PLCE1

1.40e-03161032EFO_0000668, MONDO_0024664
DiseaseHeadache

GPR149 MACF1 CUX1

1.47e-03641033HP_0002315
DiseaseFamilial Progressive Myoclonic Epilepsy

CHD2 PRDM8

1.59e-03171032C0751777
DiseaseAtypical Inclusion-Body Disease

CHD2 PRDM8

1.59e-03171032C0751776
DiseaseMyoclonic Epilepsies, Progressive

CHD2 PRDM8

1.59e-03171032C0751778
DiseaseBiotin-Responsive Encephalopathy

CHD2 PRDM8

1.59e-03171032C0751780
DiseaseMay-White Syndrome

CHD2 PRDM8

1.59e-03171032C0751782
DiseaseDentatorubral-Pallidoluysian Atrophy

CHD2 PRDM8

1.59e-03171032C0751781
Diseasecortical thickness

STX8 ARHGEF12 GLOD4 SHTN1 KIF20B PLEKHG1 CADPS VCAN MACF1 USP35 PLCE1

1.76e-03111310311EFO_0004840
DiseaseAction Myoclonus-Renal Failure Syndrome

CHD2 PRDM8

1.78e-03181032C0751779
DiseaseDeaf Mutism

CACNA1D BDNF

2.20e-03201032C4082305
DiseaseDeafness, Acquired

CACNA1D BDNF

2.20e-03201032C0751068
DiseaseHearing Loss, Extreme

CACNA1D BDNF

2.20e-03201032C0086395
DiseaseComplete Hearing Loss

CACNA1D BDNF

2.20e-03201032C0581883
DiseasePrelingual Deafness

CACNA1D BDNF

2.20e-03201032C0011052
DiseaseBilateral Deafness

CACNA1D BDNF

2.20e-03201032C3665473
Diseasewellbeing measurement, alcohol consumption measurement

CMYA5 AREG DST

2.24e-03741033EFO_0007869, EFO_0007878
DiseaseEpilepsy, Cryptogenic

SMC1A CHD2 BDNF

3.00e-03821033C0086237
DiseaseAwakening Epilepsy

SMC1A CHD2 BDNF

3.00e-03821033C0751111
DiseaseAura

SMC1A CHD2 BDNF

3.00e-03821033C0236018
DiseaseDeafness

CACNA1D BDNF

3.44e-03251032C0011053

Protein segments in the cluster

PeptideGeneStartEntry
QEEEGRKRYEAQKLE

ACOT7

186

O00154
QKDLNEKCLYEVGRD

ATAD5

426

Q96QE3
QYDKDNEKRTLLQCE

FAM228B

161

P0C875
YEGEAEERKKLRQEN

AREG

231

P15514
KVRPNEENNKDADLY

BDNF

76

P23560
LGQFERTQEEYEDKK

VCAN

2741

P13611
LKDFQYIDRDGKDQG

EPN3

106

Q9H201
LIGDNDNAKKVYEEV

ASPH

466

Q12797
RFQEELGYDLKENAK

FAM186B

51

Q8IYM0
VRQDAQDLYEAGEKK

ANXA4

171

P09525
VGEYAKLEKINAEQQ

CIT

621

O14578
LGCKEEDNVQKNYEL

EFR3A

536

Q14156
QAVKEAENKQRLEDY

ARHGEF12

976

Q9NZN5
NKEEKDVNLRISGNY

ARHGEF12

1401

Q9NZN5
EKYNGNRIGLEEEKL

PTPN2

311

P17706
ENIRALKDGYEKVEQ

P4HA3

111

Q7Z4N8
KQAVIGNLDEEQYKL

KIAA0513

386

O60268
LDQGKYDADDNVKII

RABL2A

11

Q9UBK7
LDQGKYDADDNVKII

RABL2B

11

Q9UNT1
DYRQLEKELQGQNVE

ANKRD13A

21

Q8IZ07
YAKIEENQKDAENVG

CADPS

856

Q9ULU8
DTGVRNEAQEEIYKK

GNL2

186

Q13823
EEKNIALNGEYGKEL

GRXCR1

171

A8MXD5
IRSQNKEDYAGLKEE

GSTO1

131

P78417
EEDDYQQKRKGVEGL

PDAP1

66

Q13442
GNCQKDREDLRVYEK

MTMR8

441

Q96EF0
KDEEKQRALLGYADN

GLOD4

181

Q9HC38
QVYESKLEDGNKEQE

GOLGA4

886

Q13439
RQQEYKEKLQGICDL

DST

3641

Q03001
LKDFQYIDRDGKDQG

EPN2

106

O95208
EQAKRNLEGEIQNYK

CFAP58

411

Q5T655
NLEGEIQNYKDEAQK

CFAP58

416

Q5T655
DAYRNEVELLKQEQG

ENOX2

426

Q16206
NQKLRETLEEYNKEF

CUX1

126

Q13948
QLEEKLKGQADYEEV

CUX1

351

Q13948
SQKDDEEQIAKYRQL

ESF1

571

Q9H501
QAEREYEKIKSQLEG

PLXNB2

1226

O15031
TQNLKADLQRKEEDY

KIF20B

1271

Q96Q89
DELQESEQKYNADRK

KIF20B

1446

Q96Q89
SEKQQLEEKYRQEDQ

KCNJ15

346

Q99712
CEGRDLDDKIQEYKQ

NEK11

111

Q8NG66
EGLDKLVSDANEQYK

MACF1

1766

O94854
NYSELREDIQTKGKE

L1RE1

51

Q9UN81
ERDGYQEEIQLLNKA

GPR149

706

Q86SP6
DRAYKLKQDLQRDEQ

ARHGAP6

291

O43182
KLQAQKEYLEAEENG

ESS2

61

Q96DF8
LYQAEEEFEKRQKDN

ESS2

181

Q96DF8
LQDEYDKGVNEKESL

DNAH6

2936

Q9C0G6
GNEKEVKEYAQVFRE

CTNNA1

411

P35221
YQENKKGELGILQDA

GBA3

316

Q9H227
QAEESEKRYKNGQSL

QRSL1

51

Q9H0R6
EQRLYKDDQLLDDGK

ELOB

41

Q15370
EENDEQGNYSKRKIV

AVEN

101

Q9NQS1
QEYEEQLKENASEGK

CHD2

1186

O14647
NPEKRKQYDLTGNEE

DNAJB14

161

Q8TBM8
QEENAVDVKQYRDKL

FNIP1

656

Q8TF40
EELDYAVLKLKENGQ

FAM111A

436

Q96PZ2
LSDQDEEGKIKQEYI

CMYA5

51

Q8N3K9
KLQDEGQEAEGEKYI

IFIT1B

226

Q5T764
VLTGYQVDKNKDDEL

CSTA

81

P01040
QGQQEDLEEKLKEYV

IFRD2

131

Q12894
GAENKIQELNAIYKE

MCF2L

506

O15068
KLQDEGQEAEGEKYI

IFIT1

226

P09914
IYDQRRIDKKENNGV

DCAF8L1

361

A6NGE4
NQLAEKEEYEHQKRE

HSPA6

586

P17066
REQVQDLFNKKYGEA

GTF2IRD1

706

Q9UHL9
LDSDRGQEVKQKYLE

DNAH10

596

Q8IVF4
RDDYIGQVAKEIENK

DNAH10

4196

Q8IVF4
QKRQINYKEDSESDG

RSF1

1211

Q96T23
REKQQLEEDLKGYLD

CACNA1D

426

Q01668
KGEEELQKYIQESQA

AFP

396

P02771
EADKLVRQYNEEGRK

HNRNPUL1

586

Q9BUJ2
EALEKYGKDFNDIRQ

MTA3

281

Q9BTC8
KVQEQLGNDVVEKYD

PMM2

51

O15305
EELAQLRDAYQKQKE

SYNC

286

Q9H7C4
SKDELENGYINFDKR

RGL2

446

O15211
QLGNSKEDKEADYRV

TEX55

376

Q96M34
KGDNNEVDDRGLYKE

SEC11C

126

Q9BY50
EIYNAESRNKDDGKV

TEX14

916

Q8IWB6
RGKEAEEQRQKEAYL

PSD

931

A5PKW4
NQFIKANEKYGRDDI

SMARCA1

866

P28370
AEEAYKQQIKEDNIG

NKRF

541

O15226
GEEFYLDQNKKESRQ

PLCE1

1646

Q9P212
RDKEEQNLEAYIKNG

PRDM8

96

Q9NQV8
TEKYENEGQRINARK

SH3YL1

211

Q96HL8
GDNNEQNYIKDVKLE

SETX

666

Q7Z333
QTGEREAKLQYEDKF

SIL1

96

Q9H173
IGEYEDLRAENQKTK

SHTN1

21

A0MZ66
AREIGDKQERKYNQL

SPATA31E1

1236

Q6ZUB1
LYGKRRSQKEEDEQE

SMARCC1

351

Q92922
RQADSKQYGDKIIEE

OS9

261

Q13438
DIGVKYSEKQERNFD

CNN2

141

Q99439
EYDAQLRREEKKFNG

RIOK3

91

O14730
LNTDELGQKEEAKNY

SPART

31

Q8N0X7
AYLQELKEKVENGSE

GGCX

616

P38435
KENEENQKSYGERLQ

RNF34

301

Q969K3
NQKSYGERLQLQDEE

RNF34

306

Q969K3
QNGQAIRAKYKEESD

TMEM181

596

Q9P2C4
EDDKRNQGNLYDKAG

STT3B

501

Q8TCJ2
KDNILYLQEQEKEAR

USP35

956

Q9P2H5
NELGQVEEEYKLRKA

TBC1D16

406

Q8TBP0
QKADEYLREIQELGQ

VPS16

361

Q9H269
GIIAEYNKINDVKED

TBC1D9

121

Q6ZT07
QGRDLTLEENQVKKY

SMC1A

361

Q14683
VRLNEAEQKYKDIQD

SMC6

316

Q96SB8
EQQKESILEKYGGQE

SLU7

366

O95391
AEKIQQRNQYERKGE

STX8

21

Q9UNK0
YAGEKAEAIQNKEQE

SPTB

1866

P11277
ERKKYNVDQSVGNND

ZGRF1

381

Q86YA3
VKGYLNQVDLQEKAD

TTC12

211

Q9H892
YNFDLRGKDKSENQD

SH3RF2

196

Q8TEC5
YDDKDGLRKEELNAI

SF3A3

61

Q12874
DLENYIKKNEDKARD

PLEKHG1

841

Q9ULL1
KQQEAQGEKASRYIE

UBXN8

86

O00124
ESDENEKEEYQNKKR

TTLL7

561

Q6ZT98
AEGNDLFREKDYKQA

ZC3H7B

41

Q9UGR2