Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	3.56e-07	12	99	4	PF15371
Domain	DUF4599	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5	3.56e-07	12	99	4	IPR027970
Domain	PLXDC	PLXDC1 PLXDC2	2.78e-05	2	99	2	IPR031152
Domain	ZF_PHD_2	TCF20 KMT2E KMT2C ASXL3 KAT6B	1.50e-04	95	99	5	PS50016
Domain	ZF_PHD_1	TCF20 KMT2E KMT2C ASXL3 KAT6B	1.58e-04	96	99	5	PS01359
Domain	USP_CS	USP9X USP29 USP31 USP38	4.16e-04	66	99	4	IPR018200
Domain	HEAT_REPEAT	SMG1 SF3B1 MROH1 MROH7	5.21e-04	70	99	4	PS50077
Domain	USP_1	USP9X USP29 USP31 USP38	5.21e-04	70	99	4	PS00972
Domain	UCH	USP9X USP29 USP31 USP38	5.50e-04	71	99	4	PF00443
Domain	USP_2	USP9X USP29 USP31 USP38	5.50e-04	71	99	4	PS00973
Domain	USP_3	USP9X USP29 USP31 USP38	5.80e-04	72	99	4	PS50235
Domain	USP_dom	USP9X USP29 USP31 USP38	5.80e-04	72	99	4	IPR028889
Domain	Peptidase_C19_UCH	USP9X USP29 USP31 USP38	5.80e-04	72	99	4	IPR001394
Domain	ARM-like	SMG1 USP9X SF3B1 MROH1 TTC12 MROH7 AGBL1	5.86e-04	270	99	7	IPR011989
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	1.36e-12	6	105	5	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	1.36e-12	6	105	5	25930072
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	SPATA31A3 SPATA31A7 SPATA31A6 SPATA31A5 SPATA31A1	9.25e-09	24	105	5	32212159
Pubmed	A human MAP kinase interactome.	HIVEP1 HIVEP2 TCF20 MAP3K3 KMT2C USF3 SF3B1 NAV3 ROBO1 TXLNG ZHX1	2.71e-07	486	105	11	20936779
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AKAP6 SMG1 SPG11 BCOR ANKHD1 KMT2C USP38 BOP1 KAT6B HERC4 MED13	6.25e-07	529	105	11	14621295
Pubmed	Interaction network of human early embryonic transcription factors.	EPC2 HIVEP1 HIVEP2 TCF20 BCOR SOX13 KMT2C ASXL3 ZHX1	1.26e-06	351	105	9	38297188
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 SCRN3 SRGAP2 PATL1 CUBN BCOR ANKHD1 MAP3K3 ZNF750 KMT2C BOP1 P2RY14 BIN2 HERC4	4.94e-06	1084	105	14	11544199
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	HIVEP1 TCF20 KMT2E ANKHD1 KMT2C SF3B1 PHACTR4	7.22e-06	233	105	7	37704626
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AKAP6 XRN2 HIVEP2 USP9X ETS2 SRGAP2 CMYA5 TRIM52 STAT3 SF3B1 NAV3 PKNOX1 ROBO1 TXLNG MED13	7.43e-06	1285	105	15	35914814
Pubmed	Myelodysplastic Syndrome/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis with Cooccurrent SF3B1 and MPL Gene Mutations: A Case Report and Brief Review of the Literature.	MPL SF3B1	9.03e-06	2	105	2	31858134
Pubmed	Identification of PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF.	PLXDC1 PLXDC2	9.03e-06	2	105	2	25535841
Pubmed	Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV).	PLXDC1 PLXDC2	9.03e-06	2	105	2	33657166
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HIVEP1 HIVEP2 TCF20 ETS2 SOX13 STAT3 KMT2C OTX1 PKNOX1 BOP1 KAT6B	1.03e-05	709	105	11	22988430
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	XRN2 HIVEP1 TCF20 PATL1 BCOR SF3B1 PHACTR4 KAT6B ZHX1 MED13 IQCK	2.31e-05	774	105	11	15302935
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SMG1 HIVEP1 TCF20 DYNC2H1 USP9X MUC16 BCOR ADAMTS6 ASXL3 UTY	2.43e-05	638	105	10	31182584
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	XRN2 HIVEP1 ANKHD1 STAT3 PLXDC2 HACE1 TXLNG	2.53e-05	283	105	7	21903422
Pubmed	Tumor-Derived Exosomal miR-29b Reduces Angiogenesis in Pancreatic Cancer by Silencing ROBO1 and SRGAP2.	SRGAP2 ROBO1	2.70e-05	3	105	2	36277474
Pubmed	RIN3 is a negative regulator of mast cell responses to SCF.	RIN3 BIN2	2.70e-05	3	105	2	23185384
Pubmed	Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R.	PLXDC1 PLXDC2	2.70e-05	3	105	2	15574754
Pubmed	The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism.	SRGAP2 ROBO1	2.70e-05	3	105	2	26365803
Pubmed	Uncommon somatic mutations in metastatic NUT midline carcinoma.	KMT2C SF3B1	2.70e-05	3	105	2	28967088
Pubmed	Screening for MPL mutations in essential thrombocythemia and primary myelofibrosis: normal Mpl expression and absence of constitutive STAT3 and STAT5 activation in MPLW515L-positive platelets.	MPL STAT3	2.70e-05	3	105	2	20113333
Pubmed	Extracellular UDP-glucose activates P2Y14 Receptor and Induces Signal Transducer and Activator of Transcription 3 (STAT3) Tyr705 phosphorylation and binding to hyaluronan synthase 2 (HAS2) promoter, stimulating hyaluronan synthesis of keratinocytes.	STAT3 P2RY14	2.70e-05	3	105	2	24847057
Pubmed	Oncogenic role of rab escort protein 1 through EGFR and STAT3 pathway.	CHM STAT3	2.70e-05	3	105	2	28230863
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	EPC2 HIVEP1 TCF20 DYNC2H1 MSH4 BCOR ZNF518A KMT2C	2.91e-05	398	105	8	35016035
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	DYNC2H1 RNF213	5.40e-05	4	105	2	26147384
Pubmed	The structural evolution of a P2Y-like G-protein-coupled receptor.	GPR34 P2RY14	5.40e-05	4	105	2	12835326
Pubmed	Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis.	PNPLA2 STAT3	5.40e-05	4	105	2	29692363
Pubmed	Querkopf, a MYST family histone acetyltransferase, is required for normal cerebral cortex development.	OTX1 KAT6B	5.40e-05	4	105	2	10821753
Pubmed	The ubiquitin ligase HERC4 suppresses MafA transcriptional activity triggered by GSK3β in myeloma by atypical K63-linked polyubiquitination.	STAT3 HERC4	5.40e-05	4	105	2	37028761
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	XRN2 TCF20 BCOR STAT3 KMT2C SF3B1	5.72e-05	220	105	6	35785414
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	XRN2 HIVEP1 DYNC2H1 USP9X ZGRF1 BCOR SOX13 FAM83B FBXO42	7.56e-05	588	105	9	38580884
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	XRN2 ZGRF1 BCOR MAST2 SF3B1 UTY	8.04e-05	234	105	6	36243803
Pubmed	Genetic link between renal birth defects and congenital heart disease.	DYNC2H1 ADAMTS6 ROBO1	8.29e-05	28	105	3	27002738
Pubmed	Identification of Pathogenic Cardiac CD11c+ Macrophages in Nod1-Mediated Acute Coronary Arteritis.	NOD1 SIGLEC1	8.97e-05	5	105	2	25838430
Pubmed	Expression of Plxdc2/TEM7R in the developing nervous system of the mouse.	PLXDC1 PLXDC2	1.34e-04	6	105	2	17280871
Pubmed	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.	SRGAP2 ROBO1	1.34e-04	6	105	2	11672528
Pubmed	Genome-wide association study of selenium concentrations.	DYNC2H1 CMYA5 PKNOX1	1.63e-04	35	105	3	25343990
Pubmed	DNA Damage Regulates Translation through β-TRCP Targeting of CReP.	HIVEP1 HIVEP2 MED13	1.63e-04	35	105	3	26091241
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	HIVEP1 TCF20 ETS2 SOX13 STAT3 ZNF750 OTX1 PKNOX1 KAT6B UTY	1.72e-04	808	105	10	20412781
Pubmed	Cell surface tumor endothelial markers are conserved in mice and humans.	PLXDC1 PLXDC2	1.88e-04	7	105	2	11559528
Pubmed	Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.	SRGAP2 ROBO1	1.88e-04	7	105	2	21655271
Pubmed	High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.	DNAJC21 ANKHD1 SOX13 KMT2C	1.94e-04	94	105	4	16325481
Pubmed	Disruption of MeCP2-TCF20 complex underlies distinct neurodevelopmental disorders.	TCF20 SF3B1	2.50e-04	8	105	2	35074918
Pubmed	Self-stabilizing regulation of deubiquitinating enzymes in an enzymatic activity-dependent manner.	USP29 USP38	2.50e-04	8	105	2	33864866
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	KMT2E KMT2C	2.50e-04	8	105	2	23130995
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	RNF213 BCOR ANO8 HERC4	2.56e-04	101	105	4	10997877
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TBC1D15 TCF20 USP9X BCOR ANKHD1 STAT3 KMT2C PHACTR4	2.68e-04	549	105	8	38280479
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	HIVEP1 HIVEP2 TCF20 SRGAP2 MAST2 STAT3 MAP3K3 FAM83B USP31 PHACTR4	2.85e-04	861	105	10	36931259
Pubmed	Human transcription factor protein interaction networks.	SMG1 EPC2 XRN2 HIVEP1 TCF20 USP9X PATL1 BCOR ANKHD1 SOX13 STAT3 KMT2C ZHX1	3.76e-04	1429	105	13	35140242
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	TENM1 FLRT2	4.00e-04	10	105	2	38713721
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 SMG1 PNPLA2 HIVEP1 ETS2 SOX13 ZNF518A SF3B1	4.37e-04	591	105	8	15231748
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	KMT2E KMT2C UTY	4.45e-04	49	105	3	34368113
Pubmed	Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity.	ETS2 SLC18A2	4.88e-04	11	105	2	20610757
Pubmed	Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling.	GPR55 ROBO1	4.88e-04	11	105	2	25030704
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PNPLA2 RIN3 HIVEP2 SRGAP2 ANKHD1 MAST2 ANO8 KMT2C MROH1 C1orf50 MED13	5.19e-04	1105	105	11	35748872
Pubmed	Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.	XRN2 USP9X SF3B1	5.31e-04	52	105	3	24591637
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TMEM144 HIVEP2 RNF213 SRGAP2 PATL1 ANO8 KMT2C USF3 PLXDC2 FBXO42 TTC12 LRRC7 KAT6B	5.53e-04	1489	105	13	28611215
Pubmed	Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration.	BCOR ARR3	5.84e-04	12	105	2	36070393
Pubmed	IL-7Rα glutamylation and activation of transcription factor Sall3 promote group 3 ILC development.	STAT3 AGBL1	5.84e-04	12	105	2	28794449
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	AKAP6 SMG1 ZNF518A KMT2C KAT6B	6.19e-04	225	105	5	12168954
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	HIVEP1 HIVEP2 MAST2 BOP1	6.28e-04	128	105	4	25332235
Pubmed	A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve.	APCDD1 ASXL3	6.89e-04	13	105	2	36325906
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2E KMT2C KAT6B	6.95e-04	57	105	3	18022353
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	HIVEP2 BCOR MAST2 FBXW8 SF3B1	7.11e-04	232	105	5	25515538
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	HIVEP1 HIVEP2 BCOR ZNF518A KMT2C FBXW8 FBXO42	7.78e-04	495	105	7	27705803
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	AKAP6 SMG1 HIVEP1 CMYA5 KMT2E MAST2 MED13	7.96e-04	497	105	7	23414517
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ZGRF1 SRGAP2 MAST2 SCMH1 BIN2 HERC4	8.38e-04	363	105	6	14691545
Pubmed	Phenotypic annotation of the mouse X chromosome.	USP9X BCOR TXLNG	8.47e-04	61	105	3	20548051
Pubmed	Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation.	ETS2 ROBO1 FLRT2	8.88e-04	62	105	3	19463158
Pubmed	Lysophospholipid receptor nomenclature review: IUPHAR Review 8.	GPR34 GPR55	9.24e-04	15	105	2	24602016
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	ZGRF1 LGSN SF3B1 ADAMTS6 ASXL3 HACE1 TENM1	9.57e-04	513	105	7	25798074
Pubmed	ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.	ETS2 ADAMTS6	1.19e-03	17	105	2	10464288
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	ETS2 SOX13 OTX1 PKNOX1 ZHX1	1.24e-03	263	105	5	20932939
Pubmed	The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.	SMG1 XRN2	1.34e-03	18	105	2	25220460
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	USP9X UTY	1.34e-03	18	105	2	12023983
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	SMG1 USP9X MUC16 RNF213 SF3B1 ASXL3 TENM1	1.46e-03	552	105	7	10737800
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	KMT2C ASXL3	1.66e-03	20	105	2	29785026
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	KMT2C UTY	1.66e-03	20	105	2	19047629
Pubmed	Molecular characterization of a novel transcription factor that controls stromelysin expression.	TCF20 OTX1	1.66e-03	20	105	2	7760812
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TBC1D15 HIVEP1 TCF20 ZGRF1 BCOR ANKHD1	1.72e-03	418	105	6	34709266
Pubmed	A census of human transcription factors: function, expression and evolution.	HIVEP1 HIVEP2 ETS2 SOX13 STAT3 OTX1 USF3 PKNOX1 ZHX1	1.75e-03	908	105	9	19274049
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2E KMT2C	1.83e-03	21	105	2	27626377
Pubmed	Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.	DYNC2H1 NAV3	1.83e-03	21	105	2	24057671
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP29 USP31 USP38	1.92e-03	81	105	3	12838346
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2E KMT2C	2.00e-03	22	105	2	26886794
Pubmed	Genome-wide association analysis identifies 20 loci that influence adult height.	ILRUN SCMH1	2.00e-03	22	105	2	18391952
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	EPC2 RNF213 BCOR ANKHD1 MAST2 ZNF518A SIGLEC1 KAT6B C1orf50 AGBL1	2.05e-03	1116	105	10	31753913
Pubmed	Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer.	OTX1 ROBO1	2.19e-03	23	105	2	30470893
Pubmed	Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.	USP31 USP38	2.19e-03	23	105	2	14715245
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	SMG1 EPC2 CHM USP38	2.49e-03	186	105	4	33637726
Pubmed	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	ILRUN SCMH1 HACE1	2.68e-03	91	105	3	20546612
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	AKAP6 SF3B1 PHACTR4	2.76e-03	92	105	3	15840729
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	HACE1 HERC4	2.80e-03	26	105	2	26949039
Cytoband	Xp11.4	GPR34 USP9X BCOR	6.61e-05	34	105	3	Xp11.4
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	1.44e-04	8	105	2	chr9q12
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	SMG1 LDAF1 USP31 IQCK	6.77e-04	172	105	4	chr16p12
Cytoband	10p12.31	CUBN PLXDC2	1.16e-03	22	105	2	10p12.31
Cytoband	9p13.1	SPATA31A3 SPATA31A1	1.38e-03	24	105	2	9p13.1
Cytoband	1p34	MPL SCMH1	2.46e-03	32	105	2	1p34
Cytoband	16p12.3	SMG1 IQCK	2.77e-03	34	105	2	16p12.3
GeneFamily	Ubiquitin specific peptidases	USP9X USP29 USP31 USP38	5.16e-05	56	66	4	366
GeneFamily	Maestro heat like repeat containing	MROH1 MROH7	7.07e-04	11	66	2	636
Coexpression	GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN	TCF20 DYNC2H1 ST8SIA1 FAM83B PLXDC2 SCMH1 UTY	1.23e-06	139	102	7	M2928
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	SMG1 USP9X ST8SIA1 MAST2 KMT2C PHACTR4 MED13	6.83e-06	180	102	7	M8239
Coexpression	GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN	RIN3 HIVEP2 RNF213 USF3 NOD1 HACE1 MED13	1.31e-05	199	102	7	M3177
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	SMG1 TBC1D15 PLXDC1 DNAJC21 RNF213 MSH4 KMT2E CHM ANKHD1 ZNF518A KMT2C SF3B1 SCMH1 FLRT2 TXLNG	3.87e-06	776	101	15	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#5_top-relative-expression-ranked_1000	TBC1D15 PLXDC1 DNAJC21 RNF213 MSH4 ZNF518A KMT2C	2.38e-05	179	101	7	gudmap_developingGonad_e14.5_ ovary_1000_k5
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SMG1 HIVEP2 RNF213 STAT3 KMT2C UTY	1.91e-06	156	105	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	ASK428-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	STARD13 ST8SIA1 SOX13 SLC18A2 TENM1 ROBO1	2.94e-06	168	105	6	c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 HIVEP1 USP9X STAT3 SF3B1 UTY	5.12e-06	185	105	6	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	Control-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	PLXDC1 FAM83B USP31 PLXDC2 ASXL3 ROBO1	5.12e-06	185	105	6	d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AKAP6 STARD13 GPR34 SRGAP2 P2RY14 SIGLEC1	5.96e-06	190	105	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	RIN3 GPR34 SRGAP2 PLXDC2 P2RY14 SIGLEC1	6.14e-06	191	105	6	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	RIN3 GPR34 SRGAP2 PLXDC2 P2RY14 SIGLEC1	6.33e-06	192	105	6	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR34 SRGAP2 PLXDC2 P2RY14 BIN2 SIGLEC1	6.52e-06	193	105	6	bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 PLXDC1 ETS2 KMT2C PLXDC2 UTY	6.52e-06	193	105	6	a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR34 SRGAP2 PLXDC2 P2RY14 BIN2 SIGLEC1	6.52e-06	193	105	6	374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RIN3 GPR34 SRGAP2 P2RY14 BIN2 SIGLEC1	6.72e-06	194	105	6	0866ab6792cee274a71991d5c37a37f574ff446e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RIN3 GPR34 SRGAP2 P2RY14 SIGLEC1	6.72e-06	194	105	6	c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	AKAP6 STARD13 PLXDC1 GPR34 P2RY14 SIGLEC1	6.92e-06	195	105	6	4008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 RIN3 GPR34 SRGAP2 P2RY14 SIGLEC1	7.12e-06	196	105	6	cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	AKAP6 STARD13 PLXDC1 GPR34 P2RY14 SIGLEC1	7.12e-06	196	105	6	e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	HIVEP1 HIVEP2 MUC16 CMYA5 FAM83B OTX1	7.33e-06	197	105	6	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR34 ETS2 RNF213 SRGAP2 PLXDC2 BIN2	7.77e-06	199	105	6	e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 RNF213 KMT2E KMT2C SF3B1 SIGLEC1	7.99e-06	200	105	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l14\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR34 BCOR SLC18A2 P2RY14 IQCK	3.03e-05	152	105	5	0fda8980b10ce16179dea92301db74d728f41794
ToppCell	Adult-Immune-mast_cell\|Adult / Lineage, Cell type, age group and donor	GPR34 ST8SIA1 SLC18A2 TENM1 P2RY14	3.99e-05	161	105	5	44f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	STARD13 GPR34 PLXDC2 P2RY14 SIGLEC1	4.61e-05	166	105	5	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR34 SRGAP2 PLXDC2 NAV3 BIN2	4.75e-05	167	105	5	942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHM TRIM52 FBXW8 PKNOX1 ROBO1	4.88e-05	168	105	5	53a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLXDC1 ZGRF1 ST8SIA1 CMYA5 P2RY14	5.31e-05	171	105	5	2dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLXDC1 ZGRF1 ST8SIA1 CMYA5 P2RY14	5.31e-05	171	105	5	2aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCell	droplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 ZGRF1 ST8SIA1 CMYA5 P2RY14	5.61e-05	173	105	5	8fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCell	droplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 ZGRF1 ST8SIA1 CMYA5 P2RY14	5.61e-05	173	105	5	f663571aaae2365660a8b526c355f4bd1a124a74
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR34 BCOR SLC18A2 P2RY14 IQCK	5.77e-05	174	105	5	e9e4532a474b4b0938a50ff85c9508aca53cd3ae
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-ILC\|Multiple_Sclerosis / Disease, Lineage and Cell Type	EPC2 ZGRF1 LGSN HACE1 IQCK	5.77e-05	174	105	5	7c50bf9da37711266cc077eef4e54b58463f1d37
ToppCell	facs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 ST8SIA1 CMYA5 ITGAD P2RY14	6.09e-05	176	105	5	74f851a398c7562dd713bc0d8d488c0037243112
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 GPR55 ST8SIA1 ADAMTS6 P2RY14	6.09e-05	176	105	5	3d372c1d527fcc118d1e5809f2524fc387682472
ToppCell	facs-Marrow-T_cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 ST8SIA1 CMYA5 ITGAD P2RY14	6.09e-05	176	105	5	31b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell	facs-Skin-Telogen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 GPR55 ST8SIA1 ADAMTS6 P2RY14	6.09e-05	176	105	5	7b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR34 GPR55 ST8SIA1 ADAMTS6 P2RY14	6.09e-05	176	105	5	9c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCell	BAL-Severe-cDC_3\|Severe / Compartment, Disease Groups and Clusters	RIN3 ETS2 GPR55 USF3 P2RY14	6.26e-05	177	105	5	939487a05311b66edfc3f44a7955fbf25266d6bf
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 PLXDC2 ADAMTS6 P2RY14 KAT6B	6.60e-05	179	105	5	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	facs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 ST8SIA1 CMYA5 ITGAD P2RY14	6.95e-05	181	105	5	782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCell	facs-Marrow-B-cells-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 ST8SIA1 CMYA5 ITGAD P2RY14	6.95e-05	181	105	5	e2481291c236105774c53883e6f20da11941df9b
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	SMG1 RNF213 ST8SIA1 HERC4 UTY	6.95e-05	181	105	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	USP9X ETS2 RNF213 KMT2C PHACTR4	7.32e-05	183	105	5	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR34 ETS2 SRGAP2 PLXDC2 NAV3	7.32e-05	183	105	5	614a1c08cf6d01a4f1ed2fb816cd1a6e0c3207ce
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	GPR34 STAT3 PLXDC2 NAV3 ROBO1	7.51e-05	184	105	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RIN3 ST8SIA1 PLXDC2 ROBO1 LRRC7	7.71e-05	185	105	5	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	TCF20 SCMH1 PHACTR4 ROBO1 MED13	7.91e-05	186	105	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ETS2 MUC16 KMT2C PLXDC2 FLRT2	7.91e-05	186	105	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TCF20 SCMH1 PHACTR4 ROBO1 MED13	7.91e-05	186	105	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ST8SIA1 ADAMTS6 ROBO1 LRRC7 FLRT2	8.11e-05	187	105	5	5258674d0346e5c51a4b965efcdc1790c970845d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 USP9X RNF213 KMT2C MED13	8.32e-05	188	105	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	ASK440-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	GPR34 ST8SIA1 ZNF750 SLC18A2 P2RY14	8.53e-05	189	105	5	72a19b20cb0f7283afe5f85d62a21cff69fd78d0
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STARD13 RIN3 PLXDC2 P2RY14 SIGLEC1	8.53e-05	189	105	5	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 GPR34 P2RY14 BIN2 SIGLEC1	8.74e-05	190	105	5	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR34 ETS2 SRGAP2 PLXDC2 NAV3	8.74e-05	190	105	5	0a944da2aaaef9289b2a4ffe360b0338724fd59b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIN3 GPR34 P2RY14 BIN2 SIGLEC1	8.96e-05	191	105	5	baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	RIN3 RNF213 SRGAP2 P2RY14 SIGLEC1	9.18e-05	192	105	5	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	XRN2 HIVEP1 KMT2E ROBO1 MED13	9.18e-05	192	105	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR34 RNF213 ITGAD PLXDC2 SIGLEC1	9.18e-05	192	105	5	935a4a36881a9fa4daa02cba96af07f6686ed8d6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SMG1 RNF213 STAT3 KMT2C UTY	9.18e-05	192	105	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	ILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ST8SIA1 CMYA5 USP31 PLXDC2 FLRT2	9.18e-05	192	105	5	d43caf42ec744e895137f31ef65a990e250669d2
ToppCell	RV-08._Macrophage\|RV / Chamber and Cluster_Paper	RIN3 SRGAP2 PLXDC2 P2RY14 SIGLEC1	9.41e-05	193	105	5	12bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	USP9X BCOR USF3 USP38 MED13	9.41e-05	193	105	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	XRN2 HIVEP1 KMT2E ROBO1 MED13	9.41e-05	193	105	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ETS2 KMT2C PLXDC2 UTY	9.64e-05	194	105	5	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	LA-08._Macrophage\|World / Chamber and Cluster_Paper	RIN3 SRGAP2 PLXDC2 P2RY14 SIGLEC1	9.64e-05	194	105	5	c1805572bcc11b1cd29083329d7b5911489fb758
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ETS2 KMT2C PLXDC2 UTY	9.64e-05	194	105	5	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 GPR34 SRGAP2 P2RY14 SIGLEC1	9.64e-05	194	105	5	abce1e824ce2512741c313a5ec336d12f580b093
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ST8SIA1 PLXDC2 ASXL3 ROBO1 LRRC7	9.64e-05	194	105	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ETS2 KMT2C PLXDC2 UTY	9.64e-05	194	105	5	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	kidney_cells-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 GPR34 SRGAP2 P2RY14 SIGLEC1	9.64e-05	194	105	5	6810586080cc893e3270b9c8bee2d95ed78e2893
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 GPR34 SRGAP2 PLXDC2 SIGLEC1	9.64e-05	194	105	5	45708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR34 SRGAP2 PLXDC2 BIN2 SIGLEC1	9.87e-05	195	105	5	91a3c439f10c03c5d51d904f512b6a08040edc76
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RIN3 ETS2 SRGAP2 PLXDC2 P2RY14	9.87e-05	195	105	5	62dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 SRGAP2 PLXDC2 P2RY14 SIGLEC1	9.87e-05	195	105	5	247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 PLXDC1 GPR34 SRGAP2 SIGLEC1	9.87e-05	195	105	5	42bfdff88da1d07828c0ad65d412fb1752f0cee4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RIN3 SRGAP2 P2RY14 BIN2 SIGLEC1	9.87e-05	195	105	5	7b6c69df943842b566a596e30bb50dbe80dccc83
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMG1 RNF213 STAT3 KMT2C TENM1	1.04e-04	197	105	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIN3 GPR34 SRGAP2 P2RY14 SIGLEC1	1.04e-04	197	105	5	d95565652ca318a2298d6918d54ba6367e9560f4
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ETS2 MUC16 FAM83B USP31 ASXL3	1.04e-04	197	105	5	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PLXDC2 TENM1 NAV3 ROBO1 FLRT2	1.04e-04	197	105	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	SMG1 RNF213 KMT2E KMT2C SIGLEC1	1.04e-04	197	105	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RIN3 RNF213 PLXDC2 BIN2 SIGLEC1	1.06e-04	198	105	5	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 CMYA5 FAM83B ZNF750 ASXL3	1.06e-04	198	105	5	de5987588b9fa9ee8c595ba06d7d844ead0e3c74
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	SMG1 RNF213 KMT2E KMT2C SIGLEC1	1.06e-04	198	105	5	44417089b62056269cac38d3134ff209c05b7007
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SMG1 RNF213 KMT2E KMT2C SIGLEC1	1.06e-04	198	105	5	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ETS2 SRGAP2 MAP3K3 KMT2C PLXDC2	1.06e-04	198	105	5	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 KMT2C SCMH1 HERC4 UTY	1.09e-04	199	105	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR34 RNF213 SRGAP2 PLXDC2 SIGLEC1	1.09e-04	199	105	5	e245851a5bddf56f7e13a7fb7c5fda2fd275dae3
ToppCell	COVID-19-kidney-Epithelial_Doublet\|kidney / Disease (COVID-19 only), tissue and cell type	OR6B1 TRIM77 SPATA31A6 AGBL1	2.12e-04	124	105	4	d6f59ddb9b9df02b5201f23fa5fb78f3fd891ee9
Computational	Neighborhood of SUFU	EPC2 USP9X PKNOX1 KAT6B MED13 IQCK	6.55e-06	77	65	6	GCM_SUFU
Computational	Neighborhood of MLL	SMG1 EPC2 USP9X PATL1 PKNOX1 KAT6B IQCK	8.15e-05	174	65	7	GCM_MLL
Computational	Neighborhood of RBM8A	EPC2 USP9X PKNOX1 MED13 IQCK	1.24e-04	81	65	5	GCM_RBM8A
Computational	Neighborhood of MYST2	EPC2 KMT2E PHACTR4 PKNOX1 KAT6B MED13	5.82e-04	172	65	6	GCM_MYST2
Disease	response to cold	AKAP6 ST8SIA1	3.14e-05	3	96	2	GO_0009409
Disease	adenoid cystic carcinoma (is_implicated_in)	XRN2 KMT2C	1.04e-04	5	96	2	DOID:0080202 (is_implicated_in)
Disease	Malignant neoplasm of breast	AKAP6 DYNC2H1 ETS2 DNAJC21 CUBN STAT3 TENM1 MROH7 ROBO1 LRRC7 KAT6B	7.39e-04	1074	96	11	C0006142
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP1 HIVEP2	7.98e-04	13	96	2	DOID:0050787 (implicated_via_orthology)
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP1 HIVEP2 SOX13	8.60e-04	57	96	3	DOID:10652 (implicated_via_orthology)
Disease	unipolar depression, anxiety	GPR55 LRRC7	9.29e-04	14	96	2	EFO_0003761, EFO_0005230
Disease	T-Cell Lymphoma	STAT3 ASXL3	1.22e-03	16	96	2	C0079772
Disease	triacylglycerol 56:9 measurement	BCOR MAGEC1	1.38e-03	17	96	2	EFO_0010436
Disease	squamous cell carcinoma (is_implicated_in)	STAT3 KMT2C	1.55e-03	18	96	2	DOID:1749 (is_implicated_in)
Disease	chemokine (C-C motif) ligand 27 measurement	STARD13 USP31 LRRC7	1.56e-03	70	96	3	EFO_0008082
Disease	unipolar depression, response to bupropion, mood disorder	ADAMTS6 NAV3	1.73e-03	19	96	2	EFO_0003761, EFO_0004247, EFO_0006326
Disease	waist-hip ratio	ILRUN PNPLA2 APCDD1 DYNC2H1 SRGAP2 MAP3K3 ADAMTS6 TTC12 NAV3 ROBO1 IQCK	2.13e-03	1226	96	11	EFO_0004343
Disease	Leukemia, Myelocytic, Acute	BCOR STAT3 KMT2C SF3B1	2.49e-03	173	96	4	C0023467
Disease	partial thromboplastin time	PLXDC2 AGBL1	2.76e-03	24	96	2	EFO_0004310
Disease	mental or behavioural disorder	TCF20 CMYA5 ADAMTS6 HACE1	2.82e-03	179	96	4	EFO_0000677
Disease	Alzheimer disease, polygenic risk score	ILRUN TBC1D15 TCF20 SPG11 MAST2 ROBO1 FLRT2	3.06e-03	586	96	7	EFO_0030082, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
QVQASTPCPRTEMAS	BOP1	101	Q14137
ALCTSSPQTLPMNNS	EPC2	711	Q52LR7
TASQCSPETQPMLST	CXorf66	101	Q5JRM2
NFSATPNVTTCPMDE	GPR34	36	Q9UPC5
PNVTTCPMDEKLLST	GPR34	41	Q9UPC5
TDTINIPNPMCTAIA	ADGRG7	516	Q96K78
CSSSPQETTQSRPMP	BCOR	1436	Q6W2J9
NPEELCTSPTLMTSQ	BIN2	491	Q9UBW5
CTSPTLMTSQVASEP	BIN2	496	Q9UBW5
RELNMNLLSCPTTTP	FLRT2	351	O43155
PFTLQMVTNLPCSVT	ARR3	111	P36575
QLEVCDSLIPSTSSM	ASXL3	536	Q9C0F0
QASSDCLETVRPPSM	ADAMTS6	1051	Q9UKP5
CPLVTITAMPESNSD	AGBL1	771	Q96MI9
PTENCDVLMTFPDTT	ANO8	61	Q9HCE9
EPNSTISPPSCMTLI	MROH7	316	Q68CQ1
CEMLTEQTPSSDPEN	CHM	151	P24386
TMISRTPCPQDKSET	IQCK	106	Q8N0W5
CSGPSMEPTIQNSDI	IMMP1L	36	Q96LU5
VNDNPPEIAMTSLTS	PCDHB18P	286	Q96TA0
SCSMLQQTSISSPPT	KAT6B	1731	Q8WYB5
SQSPVRSMDEAPCVN	FBXO42	391	Q6P3S6
SLEPETTSAPNMNIT	MUC16	9481	Q8WXI7
RMSPNQLCSVPNSSL	PATL1	231	Q86TB9
ACVEPTDLLTTLSNM	PNPLA2	311	Q96AD5
CTPLSSVSRPLQMNE	KMT2C	1926	Q8NEZ4
MPSLLQSSSESPQSC	MAGEC1	11	O60732
LCMESQQILPDSSPV	MGAM2	1416	Q2M2H8
QERSMCTPLPVAAQS	LRRC7	536	Q96NW7
CKIESSIQPTSNMPN	FAM83B	941	Q5T0W9
TCVNLSDSPPNLMVS	FBXW8	436	Q8N3Y1
PLTQQNTSCDFLPAM	LDAF1	136	Q96B96
PLELTETESSMLSCQ	NAV3	41	Q8IVL0
MCPASTPSVLSSEQE	ETS2	221	P15036
PECPLMSDSNNFTTI	HERC4	511	Q5GLZ8
TPNLLPTSSTCINML	HACE1	866	Q8IYU2
SPQLPDCTMTLTDVF	NOD1	411	Q9Y239
VSMCSDIQPSSPDIE	KMT2E	671	Q8IZD2
VPAEPQTMSVLISCT	DNAJC21	471	Q5F1R6
QICVPVESSSPLVMS	MROH1	316	Q8NDA8
MVLSQVQSPFPSLCT	GPR55	81	Q9Y2T6
EEQTCPSTFSEEMTP	PHACTR4	481	Q8IZ21
PLAAPSNTSCMQRSV	OTX1	196	P32242
DVVMEAPSQSLPCVS	ITGAD	981	Q13349
CTQRSPENPMQVSST	CUBN	1466	O60494
QLDSPSVSSVLPCFM	DYNC2H1	4236	Q8NCM8
PQEIADVSVQMCSPS	ILRUN	136	Q9H6K1
TEMTSECQAPPLSAT	CMYA5	861	Q8N3K9
MPLVQCASSSPRAED	APCDD1	461	Q8J025
MAQLSSCDSPDTPET	MAST2	476	Q6P0Q8
NVELMQDLPPASSSC	C1orf174	201	Q8IYL3
MDTLLSQSVALPPCT	C1orf50	176	Q9BV19
CMRDSSQILTPPQLS	LGSN	56	Q5TDP6
PETSEQCMLDPLSSA	MAP3K3	206	Q99759
AELCTQAMALETPTP	RIN3	481	Q8TB24
ALQSIPNPSSECMLR	USP9X	1201	Q93008
SQILPSMSVSICPSS	UTY	826	O14607
CTDNPVMLDAPLVSS	STARD13	216	Q9Y3M8
SMAPLTNEIRPVSSC	LINC00869	146	P0C866
RILQPMLDSSCSETP	PKNOX1	316	P55347
SNVCPIQRETTMSPL	SPATA31A6	451	Q5VVP1
SMVSILPQDSSLPCI	SCRN3	281	Q0VDG4
SNVCPIQRETTMSPL	SPATA31A7	451	Q8IWB4
PPTVCQFITATEMTL	SMG1	2696	Q96Q15
VCLPSRDMQLPSNVS	PRSS47P	191	A8MTI9
NISAVEMTPLPTCLQ	PLXDC2	316	Q6UX71
RMQLDPCEDTSLQPT	ST8SIA1	341	Q92185
MQRVVSDPPSCDISN	TENM1	966	Q9UKZ4
MTTDCIALPSDQLPS	MSH4	541	O15457
SPSILSACLVAMEPQ	MED13	1906	Q9UHV7
ISPVLNLSCTDMSIT	OR6B1	181	O95007
MINSTSTQPPDESCS	P2RY14	1	Q15391
AATIPSSAMQAPTVC	SCMH1	346	Q96GD3
VPSEAAMPLQATACS	AKAP6	2181	Q13023
VSTQDQPMANLCTPS	ANKHD1	2031	Q8IWZ3
PSVPTSKMDSDQVCN	SPG11	1411	Q96JI7
TTPSPMQTLQEEAVC	TRIM52	6	Q96A61
SNVCPIQRETTMSPL	SPATA31A3	451	Q5VYP0
CTEMLTRNTLKPSPQ	RNF213	3866	Q63HN8
PACRQDTPTLSSMES	ZNF750	661	Q32MQ0
PTRESVPCQLSSSAM	TRIM77	76	I1YAP6
SLDPNMPVIVNTCSL	SOX13	566	Q9UN79
SNVCPIQRETTMSPL	SPATA31A1	451	Q5TZJ5
SNVCPIQRETTMSPL	SPATA31A5	451	Q5VU36
KSEIPNNTCSMDTTP	TMEM144	146	Q7Z5S9
ETCSPFTVLPALMNE	SF3B1	1121	O75533
TTCSNTIDLPMSPRT	STAT3	716	P40763
ASCRPSSQPIMSQSL	SRGAP2	871	O75044
CSPVPMLRDLTQNTV	XRN2	736	Q9H0D6
KSTTPCMVLASEQDP	ZHX1	6	Q9UKY1
SQEMISEINSPLTPS	USP29	566	Q9HBJ7
TPCPTVMRAEVSNQT	USF3	561	Q68DE3
QCPRPTSPVSTDSNM	ROBO1	1436	Q9Y6N7
SMAVIQCTVDSEPPA	SIGLEC1	1361	Q9BZZ2
ERTPLPLCSSQAQMD	MPL	576	P40238
MPANEIVITSTATCP	ZNF518A	1201	Q6AHZ1
SCSSTPSPLMQTGEN	TCF20	381	Q9UGU0
ENVVMTPCPTSAFQS	TBC1D15	646	Q8TC07
CPSSSLENMSVQDPA	USP38	621	Q8NB14
LENMSVQDPASSPSI	USP38	626	Q8NB14
TETPELPSTCMQIDF	ZGRF1	976	Q86YA3
ECRTTLNKTMISPPQ	TTC12	56	Q9H892
TSMSAVEFTPLPTCL	PLXDC1	291	Q8IUK5
SVTSPLAVNENCMRP	USP31	851	Q70CQ4
PSIRVTQLMTPSDSC	HIVEP2	1976	P31629
DLATPVMQPCTALDS	TXLNG	471	Q9NUQ3
MVTNASAVPSDCPSE	SLC18A2	106	Q05940
LDCLPITRSNSMPTT	HIVEP1	831	P15822