Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	PMS1 ATP6V1E1 DDX12P MYO1D ATP6V1E2 CHD9 SMC2 RAD50 BPTF ACSM4 ATAD3A AFG3L2 AACS CHD6	1.95e-05	614	120	14	GO:0140657
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	PMS1 DDX12P CHD9 RAD50 BPTF CHD6	1.19e-04	127	120	6	GO:0008094
GeneOntologyBiologicalProcess	vesicle cargo loading	CTAGE9 CTAGE6 CTAGE1 CTAGE8 CTAGE15 CTAGE4 AP3D1	1.63e-09	36	123	7	GO:0035459
GeneOntologyBiologicalProcess	protein secretion	CTAGE9 ILDR2 BRSK2 CTAGE6 PPID CTAGE1 CTAGE8 AACS LRRC8A CTAGE15 GNA11 CTAGE4	3.06e-05	480	123	12	GO:0009306
GeneOntologyBiologicalProcess	establishment of protein localization to extracellular region	CTAGE9 ILDR2 BRSK2 CTAGE6 PPID CTAGE1 CTAGE8 AACS LRRC8A CTAGE15 GNA11 CTAGE4	3.25e-05	483	123	12	GO:0035592
GeneOntologyBiologicalProcess	protein localization to extracellular region	CTAGE9 ILDR2 BRSK2 CTAGE6 PPID CTAGE1 CTAGE8 AACS LRRC8A CTAGE15 GNA11 CTAGE4	3.74e-05	490	123	12	GO:0071692
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization involved in establishment of planar polarity	BRSK2 BRSK1	1.05e-04	3	123	2	GO:0090176
GeneOntologyCellularComponent	endoplasmic reticulum exit site	CTAGE9 CTAGE6 CTAGE1 CTAGE8 CTAGE15 CTAGE4	1.54e-07	42	122	6	GO:0070971
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN7A	1.24e-04	17	122	3	GO:0001518
GeneOntologyCellularComponent	leading edge membrane	GABRE RIPOR2 MYO1D ADORA1 DIAPH1 AKT2 PLCG1	2.36e-04	210	122	7	GO:0031256
GeneOntologyCellularComponent	monoatomic ion channel complex	GABRE TRPC3 PTPA SCN1A SCN2A CNGB3 SCN7A LRRC8A LRRC8B	3.81e-04	378	122	9	GO:0034702
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN7A	6.34e-04	29	122	3	GO:0034706
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CTAGE9 ILDR2 RANBP2 NRAS DPY19L1 PSKH1 CTAGE6 SCD5 ANKLE2 LCLAT1 GUCY2C CTAGE1 SLC35D3 CTAGE8 PEX16 CTAGE15 LRRC8B CTAGE4	6.86e-04	1327	122	18	GO:0042175
GeneOntologyCellularComponent	transmembrane transporter complex	GABRE ATP6V1E1 TRPC3 PTPA SCN1A SCN2A CNGB3 SCN7A LRRC8A LRRC8B	9.95e-04	523	122	10	GO:1902495
GeneOntologyCellularComponent	T-tubule	ADRA1B SCN1A SCN2A CLTC	1.18e-03	79	122	4	GO:0030315
GeneOntologyCellularComponent	neuron projection membrane	GABRE RIPOR2 MYO1D ADORA1	1.36e-03	82	122	4	GO:0032589
GeneOntologyCellularComponent	endoplasmic reticulum membrane	CTAGE9 ILDR2 NRAS DPY19L1 PSKH1 CTAGE6 SCD5 ANKLE2 LCLAT1 GUCY2C CTAGE1 SLC35D3 CTAGE8 PEX16 CTAGE15 LRRC8B CTAGE4	1.37e-03	1293	122	17	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	CTAGE9 ILDR2 NRAS DPY19L1 PSKH1 CTAGE6 SCD5 ANKLE2 LCLAT1 GUCY2C CTAGE1 SLC35D3 CTAGE8 PEX16 CTAGE15 LRRC8B CTAGE4	1.44e-03	1299	122	17	GO:0098827
GeneOntologyCellularComponent	transporter complex	GABRE ATP6V1E1 TRPC3 PTPA SCN1A SCN2A CNGB3 SCN7A LRRC8A LRRC8B	1.45e-03	550	122	10	GO:1990351
Domain	Na_channel_asu	SCN1A SCN2A SCN7A	2.71e-05	10	116	3	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN7A	2.71e-05	10	116	3	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN7A	2.71e-05	10	116	3	PF06512
Domain	vATP-synt_E	ATP6V1E1 ATP6V1E2	3.82e-05	2	116	2	PF01991
Domain	ATPase_V1/A1-cplx_esu	ATP6V1E1 ATP6V1E2	3.82e-05	2	116	2	IPR002842
Domain	Clathrin_H-chain_linker	CLHC1 CLTC	1.14e-04	3	116	2	IPR012331
Domain	IQ	MYO1D SCN1A SCN2A SCN7A MYO16	1.49e-04	81	116	5	SM00015
Domain	IQ_motif_EF-hand-BS	MYO1D SCN1A SCN2A SCN7A MYO16	2.45e-04	90	116	5	IPR000048
Domain	LRRC8_Pannexin-like	LRRC8A LRRC8B	3.78e-04	5	116	2	IPR021040
Domain	Pannexin_like	LRRC8A LRRC8B	3.78e-04	5	116	2	PF12534
Domain	BRK	CHD9 CHD6	5.64e-04	6	116	2	SM00592
Domain	Na_trans_cytopl	SCN1A SCN2A	5.64e-04	6	116	2	PF11933
Domain	BRK_domain	CHD9 CHD6	5.64e-04	6	116	2	IPR006576
Domain	Na_trans_cytopl	SCN1A SCN2A	5.64e-04	6	116	2	IPR024583
Domain	BRK	CHD9 CHD6	5.64e-04	6	116	2	PF07533
Domain	7TM_GPCR_Srsx	NMUR2 SSTR2 ADORA1 ADRA1B CCR4	6.70e-04	112	116	5	SM01381
Domain	Ion_trans_dom	TRPC3 SCN1A SCN2A CNGB3 SCN7A	7.26e-04	114	116	5	IPR005821
Domain	Ion_trans	TRPC3 SCN1A SCN2A CNGB3 SCN7A	7.26e-04	114	116	5	PF00520
Domain	Chromodomain-like	ARID4A CHD9 CHD6	1.02e-03	32	116	3	IPR016197
Domain	RecF/RecN/SMC_N	SMC2 RAD50	1.04e-03	8	116	2	IPR003395
Domain	SMC_N	SMC2 RAD50	1.04e-03	8	116	2	PF02463
Domain	Chromo/shadow_dom	ARID4A CHD9 CHD6	1.11e-03	33	116	3	IPR000953
Domain	CHROMO	ARID4A CHD9 CHD6	1.11e-03	33	116	3	SM00298
Domain	Znf_C2H2_matrin	ZNF318 SF3A3	2.42e-03	12	116	2	IPR000690
Domain	IQ	MYO1D SCN1A SCN2A MYO16	2.70e-03	93	116	4	PS50096
Domain	-	ARID4A JARID2	3.81e-03	15	116	2	1.10.150.60
Domain	BRIGHT	ARID4A JARID2	3.81e-03	15	116	2	SM00501
Domain	ARID_dom	ARID4A JARID2	3.81e-03	15	116	2	IPR001606
Domain	ARID	ARID4A JARID2	3.81e-03	15	116	2	PS51011
Domain	ARID	ARID4A JARID2	3.81e-03	15	116	2	PF01388
Domain	ARM-type_fold	RIPOR2 UBR4 CLHC1 CLTC DIAPH1 AP3D1 SYMPK	5.26e-03	339	116	7	IPR016024
Domain	Channel_four-helix_dom	SCN1A SCN2A SCN7A	5.35e-03	57	116	3	IPR027359
Domain	-	SCN1A SCN2A SCN7A	5.35e-03	57	116	3	1.20.120.350
Domain	ZF_MATRIN	ZNF318 SF3A3	5.48e-03	18	116	2	PS50171
Domain	Cyclophilin-type_PPIase_CS	RANBP2 PPID	6.10e-03	19	116	2	IPR020892
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT72 RANBP2 MYO1D KRT74 UBR4 ZNF318 CTAGE6 SMC2 ANKLE2 DNTTIP2 BPTF HOOK1 ATAD3A CEP112 CTAGE1 PES1 CTAGE8 CLTC SUPT16H FAM169A CTAGE15 CHD6 CTAGE4 AP3D1	2.67e-10	1442	124	24	35575683
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PRPSAP1 GPD2 RANBP2 RRP1B UBR4 KRI1 SMC2 LCLAT1 RAD50 ATAD3A PURA PES1 AFG3L2 CNOT7 CLTC SUPT16H SF3A3 IFI44L EIF3C VPS53 AP3D1 CCDC93	7.84e-09	1440	124	22	30833792
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RANBP2 MYO1D RRP1B UBR4 KRI1 ZNF318 ME2 DNTTIP2 RAD50 BPTF ATAD3A PES1 CLTC SYMPK	9.62e-08	653	124	14	22586326
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GPD2 RANBP2 MYO1D RRP1B UBR4 KRI1 SMC2 ME2 DNTTIP2 RAD50 JARID2 ATAD3A PES1 CLTC SUPT16H DIAPH1 SF3A3 CSTF1 EIF3C PLCG1	1.61e-07	1425	124	20	30948266
Pubmed	Mea6 controls VLDL transport through the coordinated regulation of COPII assembly.	CTAGE9 CTAGE1 CTAGE8	1.76e-07	4	124	3	27311593
Pubmed	MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking.	CTAGE9 CTAGE1 CTAGE8	1.76e-07	4	124	3	31244610
Pubmed	Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.	CTAGE9 CTAGE1 CTAGE8	1.76e-07	4	124	3	21807889
Pubmed	Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance.	CTAGE9 CTAGE1 CTAGE8	1.76e-07	4	124	3	33718348
Pubmed	Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.	CTAGE9 CTAGE1 CTAGE8	1.76e-07	4	124	3	12586826
Pubmed	cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing.	CTAGE9 CTAGE1 CTAGE4	4.40e-07	5	124	3	12839582
Pubmed	Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.	CTAGE9 CTAGE1 CTAGE8	4.40e-07	5	124	3	18630941
Pubmed	Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.	CTAGE9 CTAGE1 CTAGE8	4.40e-07	5	124	3	19131326
Pubmed	Characterization and expression pattern of the novel MIA homolog TANGO.	CTAGE9 CTAGE1 CTAGE8	4.40e-07	5	124	3	15183315
Pubmed	Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development.	CTAGE9 CTAGE1 CTAGE8	4.40e-07	5	124	3	38439956
Pubmed	A tissue-specific atlas of mouse protein phosphorylation and expression.	CTAGE9 CTAGE1 CTAGE8	4.40e-07	5	124	3	21183079
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	GPD2 RANBP2 NRAS RRP1B USP28 KRI1 CMSS1 DNTTIP2 RAD50 BPTF PES1 CLTC SUPT16H SF3A3 EIF3C SYMPK	5.00e-07	989	124	16	36424410
Pubmed	Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.	RANBP2 RRP1B KRT74 KRI1 SMC2 DNTTIP2 ATAD3A PES1 CLTC SUPT16H SF3A3 EIF3C AP3D1	5.31e-07	641	124	13	36057605
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GPD2 RANBP2 MYO1D RRP1B ZNF318 SMC2 DNTTIP2 RAD50 BPTF ATAD3A PES1 AFG3L2 CLTC SUPT16H SF3A3 EIF3C	7.89e-07	1024	124	16	24711643
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	RANBP2 DPY19L1 SMC2 OLFML3 RAD50 JARID2 BPTF PES1 AFG3L2 SUPT16H CHD6	1.03e-06	469	124	11	27634302
Pubmed	cTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.	CTAGE9 CTAGE1 CTAGE8	1.53e-06	7	124	3	29133483
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	ATP6V1E1 DPYSL3 RRP1B CMSS1 SMC2 RAD50 ATAD3A CTAGE8 CLTC SF3A3 ADAMTS20 EIF3C AP3D1 CCDC93	2.12e-06	847	124	14	35235311
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	PRPSAP1 GPD2 RANBP2 RRP1B UBR4 KRI1 CMSS1 SMC2 DNTTIP2 RAD50 ATAD3A AFG3L2 CLTC SUPT16H DIAPH1 SF3A3 EIF3C AP3D1	2.88e-06	1415	124	18	28515276
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 UBR4 SMC2 RAD50 ATAD3A PES1 CLTC SUPT16H DIAPH1 EIF3C AP3D1 SYMPK	3.22e-06	638	124	12	33239621
Pubmed	Human transcription factor protein interaction networks.	MYO1D RRP1B ARID4A KRT74 UBR4 KRI1 ZNF318 RAD50 BPTF ATAD3A PURA PES1 CNOT7 CSTF1 CEP152 CHD6 EIF3C SYMPK	3.30e-06	1429	124	18	35140242
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	RANBP2 USP28 UBR4 POLR2K CHD9 SMC2 PPID RAD50 BPTF PTPA PES1 SUPT16H DIAPH1 CSTF1 SYMPK	3.49e-06	1014	124	15	32416067
Pubmed	Misexpression of MIA disrupts lung morphogenesis and causes neonatal death.	CTAGE9 CTAGE1 CTAGE8	3.66e-06	9	124	3	18342301
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	RANBP2 RRP1B UBR4 POLR2K KRI1 SMC2 DNTTIP2 ITPK1 ATAD3A PES1 AFG3L2 CLTC SUPT16H DIAPH1 SF3A3 CHD6 AP3D1	4.66e-06	1318	124	17	30463901
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	RRP1B DPY19L1 BRSK2 SMIM20 DNTTIP2 RAD50 PURA CNGB3 AFG3L2 SUPT16H AKT2 EIF3C PLCG1 BRSK1	4.84e-06	910	124	14	36736316
Pubmed	Common variants associated with general and MMR vaccine-related febrile seizures.	SCN1A SCN2A IFI44L	5.21e-06	10	124	3	25344690
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMS1 GPD2 RANBP2 DPYSL3 MYO1D RRP1B KRI1 ANKLE2 PTPA PES1 AFG3L2 CLTC SUPT16H EIF3C SYMPK	5.25e-06	1049	124	15	27880917
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	RANBP2 ZNF318 SMC2 RAD50 BPTF PES1 SF3A3 EIF3C	6.19e-06	271	124	8	32433965
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	PMS1 RANBP2 DPYSL3 USP28 ZNF318 ME2 DNTTIP2 RAD50 PES1 AFG3L2 FAM169A EIF3C PLCG1 AP3D1	6.51e-06	934	124	14	33916271
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 UBR4 CMSS1 SMC2 DNTTIP2 RAD50 ATAD3A PES1 AFG3L2 CLTC SUPT16H DIAPH1 SF3A3 CSTF1 PLCG1 AP3D1 CCDC93	6.57e-06	1353	124	17	29467282
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	GPD2 RANBP2 ATP6V1E1 NRAS RRP1B UBR4 SMC2 ME2 PPID RAD50 ATAD3A CLTC SUPT16H SF3A3 GNA11 EIF3C SYMPK	7.51e-06	1367	124	17	32687490
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	GPD2 RANBP2 RRP1B CHD9 BPTF ATAD3A PES1 CLTC SUPT16H SF3A3 CSTF1 CHD6 EIF3C AP3D1 SYMPK	7.59e-06	1082	124	15	38697112
Pubmed	STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.	CTAGE9 CTAGE1 CTAGE8 SF3A3	8.30e-06	36	124	4	33230114
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	PITPNM2 RANBP2 UBR4 WASHC3 TUBGCP5 GPR158 LRRC8A LRRC8B CHD6 AP3D1	8.37e-06	475	124	10	31040226
Pubmed	Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival.	BRSK2 AKT2 BRSK1	9.51e-06	12	124	3	23275438
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	RANBP2 RRP1B KRI1 CMSS1 DNTTIP2 ATAD3A PURA PES1 CLTC SUPT16H	9.68e-06	483	124	10	36912080
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RANBP2 RRP1B KRI1 SMC2 DNTTIP2 ATAD3A PURA PES1 SF3A3 CSTF1 LRRC8B EIF3C SYMPK	1.11e-05	847	124	13	35850772
Pubmed	Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.	CTAGE9 CTAGE1 CTAGE8	1.23e-05	13	124	3	11839810
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	RANBP2 NRAS ARID4A USP28 UBR4 CHSY1 CMSS1 SMC2 RAD50 BPTF PES1 SF3A3 SYMPK	1.25e-05	857	124	13	25609649
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	1.26e-05	2	124	2	29649454
Pubmed	Dissection of RAS downstream pathways in melanomagenesis: a role for Ral in transformation.	RALGDS NRAS	1.26e-05	2	124	2	20118982
Pubmed	Defective assembly of a hybrid vacuolar H(+)-ATPase containing the mouse testis-specific E1 isoform and yeast subunits.	ATP6V1E1 ATP6V1E2	1.26e-05	2	124	2	18662668
Pubmed	Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT.	LCP2 PLCG1	1.26e-05	2	124	2	11390650
Pubmed	Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulation.	LCP2 PLCG1	1.26e-05	2	124	2	12496421
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	1.26e-05	2	124	2	10827969
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	1.26e-05	2	124	2	19694741
Pubmed	Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain.	TRPC3 PLCG1	1.26e-05	2	124	2	15744307
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	1.26e-05	2	124	2	1317301
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	1.26e-05	2	124	2	33096315
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	1.26e-05	2	124	2	31439038
Pubmed	Functional interactions between the alpha1b-adrenoceptor and Galpha11 are compromised by de-palmitoylation of the G protein but not of the receptor.	ADRA1B GNA11	1.26e-05	2	124	2	16297597
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	1.26e-05	2	124	2	26311622
Pubmed	SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release.	BRSK2 BRSK1	1.26e-05	2	124	2	16630837
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	1.26e-05	2	124	2	15249644
Pubmed	A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E.	ATP6V1E1 ATP6V1E2	1.26e-05	2	124	2	12036578
Pubmed	Pleckstrin homology domains: two halves make a hole?	TRPC3 PLCG1	1.26e-05	2	124	2	15766521
Pubmed	The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.	SCN1A SCN2A	1.26e-05	2	124	2	21377452
Pubmed	Dual role of SLP-76 in mediating T cell receptor-induced activation of phospholipase C-gamma1.	LCP2 PLCG1	1.26e-05	2	124	2	17148460
Pubmed	T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.	LCP2 PLCG1	1.26e-05	2	124	2	15623534
Pubmed	Direct amplification of a single dissected chromosomal segment by polymerase chain reaction: a human brain sodium channel gene is on chromosome 2q22-q23.	SCN2A SCN7A	1.26e-05	2	124	2	1846440
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	1.26e-05	2	124	2	30693367
Pubmed	Investigating the regulation of brain-specific kinases 1 and 2 by phosphorylation.	BRSK2 BRSK1	1.26e-05	2	124	2	18339622
Pubmed	Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex.	BRSK2 BRSK1	1.26e-05	2	124	2	30307479
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPD2 KRT72 PITPNM2 ILDR2 ATP6V1E1 DPYSL3 MYO1D BRSK2 FGD4 ATAD3A PURA SCN2A AFG3L2 CLTC EIF3C BRSK1 AP3D1	1.36e-05	1431	124	17	37142655
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PITPNM2 RANBP2 UBR4 BRSK2 SCD5 ANKLE2 GPR158 ATAD3A SCN1A PURA AFG3L2 CLTC FAM169A AKT2 EIF3C	1.39e-05	1139	124	15	36417873
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	KRI1 DNTTIP2 ATAD3A PURA PES1 CNOT7 SF3A3 EIF3C VPS53	1.73e-05	410	124	9	26949251
Pubmed	Confirmation of quantitative trait loci for alcohol preference in mice.	SCN1A SCN2A SCN7A	1.95e-05	15	124	3	9726281
Pubmed	cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development.	CTAGE9 CTAGE1 CTAGE8	1.95e-05	15	124	3	30224460
Pubmed	Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.	MYO1D UBR4 CMSS1 SMC2 AFG3L2 AKT2 PLCG1 AP3D1	2.20e-05	323	124	8	24797263
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	PRPSAP1 RALGDS CMSS1 ITPK1 JARID2 BPTF TENM3 LRRC8A CEP152 SYMPK	2.36e-05	536	124	10	15840001
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	RANBP2 NRAS RRP1B SMC2 RAD50 AFG3L2 PLCG1	2.39e-05	237	124	7	29564676
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	PRPSAP1 RALGDS CMSS1 ITPK1 JARID2 BPTF TENM3 LRRC8A CEP152 SYMPK	2.44e-05	538	124	10	10512203
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	POLR2K CEP112 PURA PES1 CLTC EIF3C PLCG1 AP3D1	2.50e-05	329	124	8	34316702
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	RANBP2 ATP6V1E1 RRP1B DNTTIP2 ATAD3A PES1 CLTC SUPT16H CSTF1 GNA11 EIF3C	2.58e-05	660	124	11	32780723
Pubmed	An investigation into the human serum "interactome".	RANBP2 AMPD3 RRP1B JARID2 ADRA1B FAM169A	2.64e-05	162	124	6	15174051
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DPY19L1 FAM13A FAM169A CEP152 MYO16	3.05e-05	100	124	5	10048485
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	RIPOR2 RALGPS2 WASHC3 ZNF318 SCD5 ANKLE2 ME2 DNTTIP2 LCLAT1 CEP112 CLTC DIAPH1 GNA11 PLCG1	3.39e-05	1084	124	14	11544199
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	GPD2 SMC2 ME2 RAD50 HOOK1 AFG3L2 CNOT7 CLTC DIAPH1 SYMPK	3.42e-05	560	124	10	35241646
Pubmed	Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.	SCN1A SCN2A	3.77e-05	3	124	2	28784306
Pubmed	Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.	SCN1A SCN2A	3.77e-05	3	124	2	32185219
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A	3.77e-05	3	124	2	12610651
Pubmed	Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.	SCN1A SCN2A	3.77e-05	3	124	2	32005694
Pubmed	Catalysis of GTP hydrolysis by small GTPases at atomic detail by integration of X-ray crystallography, experimental, and theoretical IR spectroscopy.	RANBP2 NRAS	3.77e-05	3	124	2	26272610
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A	3.77e-05	3	124	2	23859570
Pubmed	Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells.	BRSK2 BRSK1	3.77e-05	3	124	2	22669945
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A	3.77e-05	3	124	2	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A	3.77e-05	3	124	2	17544618
Pubmed	Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity.	BRSK2 BRSK1	3.77e-05	3	124	2	20026642
Pubmed	Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis.	ANGPTL1 FAM13A	3.77e-05	3	124	2	33097673
Pubmed	GNA11 and N-RAS mutations: alternatives for MAPK pathway activating GNAQ mutations in primary melanocytic tumours of the central nervous system.	NRAS GNA11	3.77e-05	3	124	2	22758774
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A	3.77e-05	3	124	2	32845893
Pubmed	A PLC-γ1 Feedback Pathway Regulates Lck Substrate Phosphorylation at the T-Cell Receptor and SLP-76 Complex.	LCP2 PLCG1	3.77e-05	3	124	2	28644030
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A	3.77e-05	3	124	2	28518218
Pubmed	Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.	SCN1A SCN2A	3.77e-05	3	124	2	19270815
Pubmed	Microtubule stabilization specifies initial neuronal polarization.	BRSK2 BRSK1	3.77e-05	3	124	2	18268107
Pubmed	A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidification.	ATP6V1E1 ATP6V1E2	3.77e-05	3	124	2	11872743
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A SCN2A	3.77e-05	3	124	2	25155934
Interaction	CTAGE1 interactions	CTAGE6 CTAGE1 CTAGE8 CTAGE15 CTAGE4	1.92e-09	10	123	5	int:CTAGE1
Cytoband	7q35	CTAGE6 CTAGE8 CTAGE15 CTAGE4	1.55e-05	55	124	4	7q35
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	CTAGE6 CTAGE8 CTAGE15 CTAGE4	3.21e-05	66	124	4	chr7q35
Cytoband	5q31	FAM13B RAD50 PURA DIAPH1	2.78e-04	115	124	4	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	GPD2 SCN1A SCN2A SCN7A	4.05e-04	127	124	4	chr2q24
Cytoband	2q24.3	SCN1A SCN2A	8.47e-04	16	124	2	2q24.3
GeneFamily	CTAGE family	CTAGE9 CTAGE6 CTAGE1 CTAGE8 CTAGE15 CTAGE4	3.50e-11	15	82	6	907
GeneFamily	Cyclophilin peptidylprolyl isomerases	RANBP2 PPID PTPA	8.27e-05	19	82	3	909
GeneFamily	Volume regulated anion channel subunits	LRRC8A LRRC8B	2.01e-04	5	82	2	1158
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A	7.17e-04	9	82	2	1203
GeneFamily	AT-rich interaction domain containing	ARID4A JARID2	2.05e-03	15	82	2	418
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RALGPS2 PLEKHH1 FGD4 AKT2 PLCG1	2.45e-03	206	82	5	682
GeneFamily	V-type ATPases	ATP6V1E1 ATP6V1E2	4.83e-03	23	82	2	415
GeneFamily	Acyl-CoA synthetase family	ACSM4 AACS	6.15e-03	26	82	2	40
GeneFamily	Keratins, type II	KRT72 KRT74	6.63e-03	27	82	2	609
Coexpression	GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_UP	ZNF318 SMC2 JARID2 HOOK1 CEP152 PLCG1 XKRX	1.18e-05	162	123	7	M8883
Coexpression	GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_DN	USP28 RALGPS2 ANGPTL1 LCLAT1 RAD50 HOOK1 XKRX	1.61e-05	170	123	7	M2942
Coexpression	GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP	BDP1 ARID4A USP28 RALGPS2 RAD50 BPTF XKRX	1.67e-05	171	123	7	M2947
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	BDP1 RALGPS2 CHD9 GSAP ANGPTL1 IFI44L	9.09e-06	173	124	6	d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	IL34 COL16A1 OLFML3 TENM3 SLC35D3 SCN7A	1.04e-05	177	124	6	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	IL34 COL16A1 OLFML3 TENM3 SLC35D3 SCN7A	1.04e-05	177	124	6	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	COPD-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1 FGD4	1.29e-05	184	124	6	ceec41ed5636032aaf7716d1203816ea58bd39bd
ToppCell	Control-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1 FGD4	1.46e-05	188	124	6	47126c371a242c937499fd278a74a882df8f759c
ToppCell	IPF-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1 FGD4	1.55e-05	190	124	6	ffa890138394f579fee53fcfac6c121bf86adc26
ToppCell	IPF-Myeloid-cMonocyte\|IPF / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1 FGD4	1.55e-05	190	124	6	a099f51f2b7618b6712af38eedd5ee64d8663a4a
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 JARID2 BPTF MACROD2 FAM169A CHD6	1.64e-05	192	124	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	Control-Myeloid-cMonocyte\|Control / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1 FGD4	1.64e-05	192	124	6	ad04c9c4bdebf94615cee1904ca48197e62c923b
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BDP1 JARID2 BPTF MACROD2 FAM169A CHD6	1.69e-05	193	124	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	CHSY1 CMSS1 LCP2 JARID2 SAT1 FGD4	1.74e-05	194	124	6	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-CFuPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	IL34 ARID4A SCD5 SSTR2 TENM3 SCN2A	1.79e-05	195	124	6	574354ef4bcefeb9856b65d19bb92e2cffe5dc7a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS DPY19L1 SCD5 ITPK1 PLEKHH1 ADORA1	1.85e-05	196	124	6	f068ce40bf35021baf1468ae9ce30a92162eb14d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RALGPS2 SAT1 FGD4 SCN2A MACROD2 AKT2	1.90e-05	197	124	6	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	DPYSL3 COL16A1 ANGPTL1 OLFML3 TENM3 SCN7A	2.07e-05	200	124	6	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	(5)_Fibroblasts\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	DPYSL3 COL16A1 ARID4A ANGPTL1 OLFML3 SCN7A	2.07e-05	200	124	6	22c839f27d3abdf86bfabdfa305f205dd899a9dc
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	USP28 RAD50 DIAPH1 IFI44L EIF3C PLCG1	2.07e-05	200	124	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Fibroblast\|World / shred by cell class for parenchyma	DPYSL3 COL16A1 ARID4A ANGPTL1 OLFML3 SCN7A	2.07e-05	200	124	6	dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GABRE ATP6V1E2 ANGPTL1 IFI44L	4.38e-05	70	124	4	986c7a1002a4ffd3a246495bedde2997ffdc2c9d
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GABRE ATP6V1E2 ANGPTL1 IFI44L	4.38e-05	70	124	4	c0330216305491d7d57cdbea0ae3cb8e9092c8e3
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GABRE ATP6V1E2 ANGPTL1 IFI44L	4.38e-05	70	124	4	86dde790fcdaec2095e2256463953077811145d2
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GABRE ATP6V1E2 ANGPTL1 IFI44L	4.38e-05	70	124	4	e604660b2efbc03e21806dcaecf7a72321673ae2
ToppCell	LPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPD2 AMPD3 LCP2 GUCY2C CEP152	8.55e-05	160	124	5	5d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|367C / Donor, Lineage, Cell class and subclass (all cells)	KRT74 KRI1 ZNF318 SCD5 HOOK1	8.81e-05	161	124	5	f470b662566131dfe69a2fd01186ac8491196396
ToppCell	Healthy_Control-Lymphoid-B-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	RIPOR2 RALGPS2 PLEKHH1 GUCY2C MACROD2	9.33e-05	163	124	5	d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCell	Healthy_Control-Lymphoid-B\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	RIPOR2 RALGPS2 PLEKHH1 GUCY2C MACROD2	9.33e-05	163	124	5	0f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCell	COVID-19_Mild-PLT_2\|World / Disease Group and Platelet Clusters	AMPD3 USP28 SF3A3 IFI44L PLCG1	1.11e-04	169	124	5	6abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BDP1 RALGPS2 SMIM20 ANGPTL1 MACROD2	1.27e-04	174	124	5	ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 RALGPS2 ZNF318 MACROD2 EIF3C	1.34e-04	176	124	5	ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRE MYO1D SSTR2 ADRA1B TENM3	1.45e-04	179	124	5	747a32460b257fffca30527b56a74720eb9c12e4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	DIAPH1 ZNF69 CCR4 PLCG1 SYMPK	1.49e-04	180	124	5	81d60f0fa9e3b5bfcec85139a0a49e9130145f0e
ToppCell	LPS-IL1RA-Myeloid-Neutrophils-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIPOR2 GSAP LCP2 SAT1 FGD4	1.49e-04	180	124	5	c0c07937839652e01df10cc1e70aa005800ea6f6
ToppCell	LPS-IL1RA-Myeloid-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIPOR2 GSAP LCP2 SAT1 FGD4	1.49e-04	180	124	5	079c199425dd3c220f03c6dca1823946f07580a1
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIPOR2 GSAP LCP2 SAT1 FGD4	1.56e-04	182	124	5	243c783675df495ea4112dbf710712c44ea6b4f1
ToppCell	LPS_only-Myeloid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIPOR2 GSAP LCP2 SAT1 FGD4	1.56e-04	182	124	5	666ac86ee5f6fa9241ae8d80340743707e54b278
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Neutrophils-Neutrophils\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIPOR2 GSAP LCP2 SAT1 FGD4	1.56e-04	182	124	5	18790a394dc32b3cef99cdbf826392c520e38b4a
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL34 COL16A1 TRPC3 ADORA1 ADRA1B	1.65e-04	184	124	5	55dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL34 COL16A1 TRPC3 ADORA1 ADRA1B	1.65e-04	184	124	5	7128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCell	droplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL34 COL16A1 TRPC3 ADORA1 ADRA1B	1.65e-04	184	124	5	d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	DPY19L1 ZNF318 SMC2 RAD50 EIF3C	1.65e-04	184	124	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	LPS-IL1RA-Myeloid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIPOR2 GSAP LCP2 SAT1 FGD4	1.69e-04	185	124	5	9b5fd87ea9d05e051ff1251578ecfbe5e8652853
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GSAP HOOK1 GPR158 FGD4 MACROD2	1.73e-04	186	124	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	CF\|World / Disease state, Lineage and Cell class	AMPD3 RIPOR2 LCP2 JARID2 SAT1	1.77e-04	187	124	5	eec4d4e4a658e3a61c05745167a1a5e3d39bb43e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GPD2 RALGPS2 FGD4 FAM169A DIAPH1	1.82e-04	188	124	5	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL16A1 BRSK2 SCD5 SCN7A ADAMTS20	1.82e-04	188	124	5	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	COPD-Myeloid-cMonocyte\|COPD / Disease state, Lineage and Cell class	CHSY1 LCP2 JARID2 SAT1 FGD4	1.86e-04	189	124	5	d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	RANBP2 DPYSL3 CMSS1 JARID2 SAT1	1.86e-04	189	124	5	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IL34 GABRE COL16A1 ADRA1B TENM3	1.86e-04	189	124	5	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BDP1 RALGPS2 CHD9 ZNF318 MACROD2	1.86e-04	189	124	5	b13f315f617840eb5143a4e8a33a657c20365c21
ToppCell	COPD-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1	1.86e-04	189	124	5	6294691231c7d38707323cf31578a107d3b2c622
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	IL34 GABRE COL16A1 ADRA1B TENM3	1.86e-04	189	124	5	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RALGPS2 ZNF318 GSAP ANGPTL1 SCN2A	1.86e-04	189	124	5	e2bb5900d210386b7b74938e7a3636d0c7ba1bcf
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ILDR2 GSAP HOOK1 FGD4 MACROD2	1.86e-04	189	124	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PITPNM2 DPY19L1 ANKLE2 SAT1 FGD4	1.86e-04	189	124	5	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PITPNM2 DPY19L1 ANKLE2 SAT1 FGD4	1.86e-04	189	124	5	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GSAP PLEKHH1 HOOK1 GPR158 FGD4	1.91e-04	190	124	5	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RANBP2 LCP2 SAT1 FGD4 CTAGE1	1.91e-04	190	124	5	4d401b73c0e7eb38e95d0851a128bf12bb0d3a9f
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RIPOR2 RALGPS2 ZNF318 SCN2A MACROD2	1.91e-04	190	124	5	a7498fe55b7810c482291db782dc5282675d246a
ToppCell	Myeloid-Myeloid-B_(Activated_Macrophage)\|Myeloid / shred on cell class and cell subclass (v4)	RALGDS RANBP2 ATP6V1E1 GSAP CLTC	1.96e-04	191	124	5	7bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DPYSL3 COL16A1 ANGPTL1 OLFML3 SCN7A	1.96e-04	191	124	5	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC3 LCP2 SCN1A ADAMTS20 MYO16	2.01e-04	192	124	5	63d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ANGPTL1 TENM3 SCN1A MACROD2 IFI44L	2.01e-04	192	124	5	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CFuPNs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	IL34 ARID4A SCD5 SSTR2 TENM3	2.01e-04	192	124	5	a8841ebd879f1c344ab4246fdef77044170f644d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GSAP HOOK1 GPR158 FGD4 SCN1A	2.01e-04	192	124	5	b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RANBP2 BPTF HOOK1 CLTC LRRC8B	2.05e-04	193	124	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL34 DPYSL3 COL16A1 ANGPTL1 MYO16	2.05e-04	193	124	5	5bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TUBGCP5 FAM169A IFI44L PLCG1 CTAGE4	2.05e-04	193	124	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	PRPSAP1 RALGPS2 MACROD2 FAM169A CHD6	2.05e-04	193	124	5	503a979328c68b096680b71359a26f02fafdff35
ToppCell	distal-Hematologic-B_cell-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	RIPOR2 RALGPS2 GUCY2C CTAGE8 MACROD2	2.05e-04	193	124	5	202dc5ec2437602c15658074728c5f5aeeab0466
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RALGPS2 ZNF318 GSAP ANGPTL1 BPTF	2.10e-04	194	124	5	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	Control-Myeloid-cMonocyte\|World / Disease state, Lineage and Cell class	CHSY1 LCP2 JARID2 SAT1 FGD4	2.10e-04	194	124	5	f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	RANBP2 DPYSL3 CHSY1 CMSS1 SAT1	2.10e-04	194	124	5	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BDP1 RALGPS2 CHD9 MACROD2 AKT2	2.15e-04	195	124	5	481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT72 KRT74 SAT1 FAM13A GUCY2C	2.15e-04	195	124	5	23ab7e2a419377c05bab0e92a2457afbcd3d9e07
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BDP1 RALGPS2 CHD9 MACROD2 AKT2	2.15e-04	195	124	5	6108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GSAP ADORA1 HOOK1 GPR158 MACROD2	2.15e-04	195	124	5	f08e41706680881ebd0afcd08a02f8ac0089f04e
ToppCell	Control-Myeloid-ncMonocyte\|Control / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1	2.15e-04	195	124	5	fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCell	mild-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYO1D USP28 RALGPS2 IFI44L SYMPK	2.15e-04	195	124	5	1e5f1967bcc898318f4e970b844b4a944eb168e5
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT72 KRT74 SAT1 FAM13A GUCY2C	2.15e-04	195	124	5	e87b11e3242fdbed2e7f383e6876ec375af32bd4
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	RIPOR2 CHSY1 LCP2 JARID2 SAT1	2.15e-04	195	124	5	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD9 ANGPTL1 OLFML3 CEP112 SCN7A	2.15e-04	195	124	5	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	COPD-Stromal-Myofibroblast\|COPD / Disease state, Lineage and Cell class	DPYSL3 COL16A1 OLFML3 TENM3 SCN7A	2.21e-04	196	124	5	af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell	Control-Neu_4\|Control / 5 Neutrophil clusters in COVID-19 patients	GPD2 BDP1 DPY19L1 SMC2 EIF3C	2.21e-04	196	124	5	b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell	COVID-19-Myeloid-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	RIPOR2 LCP2 JARID2 SAT1 FGD4	2.21e-04	196	124	5	04d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP28 PTPA FAM13A PURA CHD6	2.21e-04	196	124	5	547901c7a665770eff78eede69b8625b416c8186
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RALGPS2 FGD4 SCN2A MACROD2 FAM169A	2.21e-04	196	124	5	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IL34 DPYSL3 COL16A1 MYO1D TENM3	2.21e-04	196	124	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	IPF-Stromal-Myofibroblast\|IPF / Disease state, Lineage and Cell class	DPYSL3 COL16A1 OLFML3 TENM3 SCN7A	2.21e-04	196	124	5	2d0a48e49b3b37bb66e33e74c52915911e1f8a74
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IL34 DPYSL3 COL16A1 MYO1D TENM3	2.21e-04	196	124	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP28 PTPA FAM13A PURA CHD6	2.21e-04	196	124	5	6e08d7ba67da161c2dca1a17c440ffb9d9b5bc3b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RANBP2 LCP2 SAT1 FGD4 IFI44L	2.21e-04	196	124	5	e54c08f88779f9fd453a4f5b85aed1f460d8a1e1
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RANBP2 CHSY1 LCP2 SAT1 FGD4	2.26e-04	197	124	5	b597c292fc1cb381a4325fed15a32966c38def28
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AMPD3 GSAP LCP2 JARID2 SAT1	2.26e-04	197	124	5	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	RIPOR2 LCP2 JARID2 SAT1 FGD4	2.26e-04	197	124	5	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	BDP1 ARID4A KRI1 RAD50 CEP152	2.26e-04	197	124	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS DPY19L1 SCD5 ITPK1 PLEKHH1	2.26e-04	197	124	5	7b12f9d4ad1e84df58e86591a491c84d4f36eac5
ToppCell	B_cells-Activate_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	AMPD3 RIPOR2 RALGPS2 GSAP IFI44L	2.31e-04	198	124	5	a663082d7fbd6db11d3d3024bbb8ba00183e19f8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGDS DPY19L1 SCD5 ITPK1 PLEKHH1	2.31e-04	198	124	5	97ae237f955fd5fbd01d06aafe89ef9e6f777a9a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	DPYSL3 RIPOR2 CHD9 BPTF FAM13A	2.31e-04	198	124	5	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	BDP1 DPYSL3 SCN2A MACROD2 MYO16	2.37e-04	199	124	5	f09b40245d3d826275bbe5f508dedccc75a911bd
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN7A	6.96e-06	10	116	3	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN7A	6.96e-06	10	116	3	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN7A	1.27e-05	12	116	3	DOID:0060170 (implicated_via_orthology)
Disease	MMR-related febrile seizures	SCN1A SCN2A IFI44L	2.60e-05	15	116	3	EFO_0006519
Disease	serine/threonine-protein kinase BRSK2 measurement	BRSK2 BRSK1	4.58e-05	3	116	2	EFO_0803063
Disease	antiphospholipid antibody measurement	CEP112 MACROD2 MYO16	1.28e-04	25	116	3	EFO_0005200
Disease	brain connectivity measurement	DPYSL3 BRSK2 CLHC1 CNOT7 MACROD2 LRRC8A ADAMTS20 MYO16	1.89e-04	400	116	8	EFO_0005210
Disease	Inflammatory Myofibroblastic Tumor	RANBP2 CLTC	2.27e-04	6	116	2	C0334121
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD6	3.18e-04	7	116	2	DOID:0050834 (implicated_via_orthology)
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	3.18e-04	7	116	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	3.18e-04	7	116	2	C0751057
Disease	Intellectual Disability	RALGDS BRSK2 BPTF SCN1A PURA SUPT16H DIAPH1 VPS53	3.98e-04	447	116	8	C3714756
Disease	Neurodevelopmental Disorders	BRSK2 SCN1A PURA SCN2A	5.06e-04	93	116	4	C1535926
Disease	Febrile Convulsions	SCN1A SCN2A	5.42e-04	9	116	2	C0009952
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	5.42e-04	9	116	2	C3502809
Disease	Bipolar Disorder	TRPC3 ME2 PPID PTPA SAT1 SCN2A AKT2 PLCG1	6.09e-04	477	116	8	C0005586
Disease	waist-hip ratio	AMPD3 ARID4A ZNF318 SMIM20 CMSS1 LCP2 ADORA1 BPTF FAM13A SCN2A ADAMTS20 AP3D1 SYMPK	1.08e-03	1226	116	13	EFO_0004343
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	1.16e-03	13	116	2	C0751122
Disease	plasminogen activator inhibitor 1 measurement	KRT72 KRT74 UBR4	1.27e-03	54	116	3	EFO_0004792
Disease	ferritin measurement	PMS1 HOOK1 TENM3 MYO16	1.27e-03	119	116	4	EFO_0004459
Disease	cortical thickness	IL34 PITPNM2 RIPOR2 RALGPS2 CHSY1 ZNF318 ME2 PPID CEP112 MACROD2 ADAMTS20 MYO16	1.47e-03	1113	116	12	EFO_0004840
Disease	idiopathic pulmonary fibrosis	PSKH1 ZNF318 FAM13A	1.48e-03	57	116	3	EFO_0000768
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	1.77e-03	16	116	2	C0393706
Disease	Global developmental delay	BRSK2 SUPT16H DIAPH1 VPS53	1.91e-03	133	116	4	C0557874
Disease	angiopoietin-related protein 1 measurement	RALGPS2 ANGPTL1	2.25e-03	18	116	2	EFO_0801382
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	2.25e-03	18	116	2	HP_0002373
Disease	Manic Disorder	TRPC3 ME2 SCN2A	2.79e-03	71	116	3	C0024713
Disease	neutrophil percentage of leukocytes	AMPD3 RIPOR2 WIPI1 KRI1 CHSY1 SCD5 HORMAD1 RAD50	2.87e-03	610	116	8	EFO_0007990
Disease	autism spectrum disorder (implicated_via_orthology)	CHD9 SCN1A SCN2A CHD6	3.10e-03	152	116	4	DOID:0060041 (implicated_via_orthology)
Disease	Autosomal Recessive Primary Microcephaly	ANKLE2 CEP152	3.36e-03	22	116	2	C3711387
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A	3.36e-03	22	116	2	DOID:2030 (implicated_via_orthology)
Disease	Manic	TRPC3 ME2 SCN2A	3.63e-03	78	116	3	C0338831

Protein segments in the cluster

Peptide	Gene	Start	Entry
RYYAMKILRKEVIIA	AKT2	176	P31751
DRYRIYKAQKLREML	BDP1	141	A6H8Y1
MLQKRIRYVVDLYLN	ANKLE2	391	Q86XL3
ETARKMRKYYLICLQ	CEP152	1306	O94986
EKLQEIRKYYMSLKS	ARID4A	1191	P29374
TELYQENEMKLYRKL	CTAGE1	356	Q96RT6
YQENEMKLYRKLTVE	CTAGE4	391	Q8IX94
MKLYRKLTVEENYRI	CTAGE4	396	Q8IX94
YQEDEMKLYRKLTVE	CTAGE6	391	Q86UF2
MKLYRKLTVEENYRI	CTAGE6	396	Q86UF2
YQENEMKLYRKLTVE	CTAGE8	391	P0CG41
MKLYRKLTVEENYRI	CTAGE8	396	P0CG41
YQENEMKLYRKLTVE	CTAGE9	391	A4FU28
MKLYRKLTVEENYRI	CTAGE9	396	A4FU28
YQENEMKLYRKLTVE	CTAGE15	391	A4D2H0
MKLYRKLTVEENYRI	CTAGE15	396	A4D2H0
YLRVKIPLRYKMVVT	ADORA1	106	P30542
MVLIYLEVFYLIRKQ	ADORA1	196	P30542
NKYREERVILFLKMA	AACS	576	Q86V21
KEQYLYTKEQLLDRM	AFG3L2	611	Q9Y4W6
YDEIKRFIRQEIIKM	COL16A1	1436	Q07092
RLVRMYFDKYVLKPA	ATAD3A	531	Q9NVI7
DYVYKRIKARRKMAD	DPYSL3	476	Q14195
TYIRQEYETKLKGLM	CEP112	901	Q8N8E3
QKLMKDYYSSRRLVI	CMSS1	96	Q9BQ75
VMYCRVYIVAKRTTK	ADRA1B	221	P35368
PTVYRMLVQKDLKRY	ACSM4	321	P0C7M7
LKMATRYRELEVKYA	ANGPTL1	166	O95841
KYKRLRSMTDVYLLN	CCR4	66	P51679
DKMSRKVRYYRLKTA	CFAP92	196	Q9ULG3
KDIIIKREMVSQYLY	DIAPH1	116	O60610
TMEERVQRRYYEKLT	BPTF	2976	Q12830
KKRLISYPRYIEIMV	ADAMTS20	251	P59510
AKALMIREKYARLAY	AMPD3	156	Q01432
YIRKKAVLIMYKVFL	AP3D1	161	O14617
FYTLVREIRQYRMKK	NRAS	156	P01111
KNYYRILMRRDQVFK	RANBP2	2966	P49792
SDKRRNYNYRVVMLK	RAD50	1176	Q92878
LLMLRKYRKDYELRQ	GUCY2C	451	P25092
YQIVYKLEMRKKEEE	OLFML3	391	Q9NRN5
YRLYMRQTIIKVIKF	LRRC8A	261	Q8IWT6
YLQKAIMKLDIEQYR	GPD2	121	P43304
RSKSYELIRKIEAYM	ITPK1	106	Q13572
KAEMLESVIKNYKRY	MAGEA9	131	P43362
VISVLYYLMALRLKK	NMUR2	231	Q9GZQ4
KRMRCEQIKAYYERE	MYO16	21	Q9Y6X6
LYAQLEIYKRKKMIT	GPR158	721	Q5T848
YLDKMITRNLKLRFY	IFI44L	131	Q53G44
KPLYDRYRLVKQMLT	FAM13B	736	Q9NYF5
LMRYSYLRLEKICLK	LCLAT1	136	Q6UWP7
RQPYAIKMIETKYRE	PSKH1	121	P11801
KMIYFLLLDRKERYP	BRSK2	331	Q8IWQ3
IYTVRNKDVKYSMRK	OR4K3	286	Q96R72
RIPRYEMLLKDYLRK	FGD4	351	Q96M96
LRARTKIVYSMYSRK	DPY19L1	581	Q2PZI1
RPMYLKDYERKVILE	KRI1	111	Q8N9T8
LMQTLKKDYRLVEYL	TUBGCP5	706	Q96RT8
KKDYRLVEYLQAMRN	TUBGCP5	711	Q96RT8
RIYKDGKVLYTIRMT	GABRE	176	P78334
EYRIAQLYMIQKKSR	PITPNM2	16	Q9BZ72
MKPLYDRYRLVKQIL	FAM13A	831	O94988
MHVEQKDIIYRVYLK	LRRC8B	246	Q6P9F7
VLMERLCKYIYAKDR	EIF3C	546	Q99613
IDYKSYMDTKLLVAR	FAM189A2	326	Q15884
MSEQRLYYIDLKKSR	GSAP	216	A4D1B5
RYNMEKEKLYKIRLL	CCDC93	456	Q567U6
KIRQVIRKYNYVAMD	CNOT7	26	Q9UIV1
KVLLRVRMLYYLKQE	CHD9	1626	Q3L8U1
LRDKLQYRSRLQYMK	IL34	41	Q6ZMJ4
CNKVLLRVRMLYYLK	CHD6	1226	Q8TD26
EKKAIYERCSRRNMY	LINC00032	71	P0C843
IRAMETLKILYKYEQ	GNA11	91	P29992
LLQYMERYGKRLKAK	DDX12P	441	Q92771
QEKMIYYLLLDRKER	BRSK1	346	Q8TDC3
LYVLNRIIYRKQEME	FAM169A	116	Q9Y6X4
MKDYLYGRLINFEKR	RALGDS	581	Q12967
KYIYIMGIQERNEKL	ME2	81	P23368
ILKERGAYKIYVMAT	PRPSAP1	271	Q14558
YKMYLEKARNVIKTL	HOOK1	606	Q9UJC3
YDALQKKYLRMVVLA	HORMAD1	86	Q86X24
MYRTKVGLKDRQQLY	CSTF1	1	Q05048
YLSKEDIQDIIYRMK	PMS1	891	P54277
VMSKEDNYKRLRDYI	RALGPS2	176	Q86X27
DNYKRLRDYISSLKM	RALGPS2	181	Q86X27
RGLKLMYRYDEEQII	JARID2	1176	Q92833
MTLEERRKEYLRDYI	MACROD2	21	A1Z1Q3
MEKLRLLGLRYQEYV	PEX16	1	Q9Y5Y5
VRGTRYMKKDYLIEN	SLC35D3	396	Q5M8T2
KYYMLIRLVLRQSFE	RRP1B	116	Q14684
KDEGLQYLERLYMKR	LRRC28	36	Q86X40
MAIKKYAEVLRYVDS	PPID	241	Q08752
YFRPLMRLEEYKKEQ	SMIM20	26	Q8N5G0
RIQRKYYKISVVLMC	SCD5	186	Q86SK9
DILRLIKELAKYEYM	SAT1	16	P21673
LRELYQEKKVYCPRM	PLB1	561	Q6P1J6
MAVTLDKDAYYRRVK	SUPT16H	1	Q9Y5B9
NTLVIYVILRYAKMK	SSTR2	61	P30874
YVILRYAKMKTITNI	SSTR2	66	P30874
YDLDKQIKTIERYMR	RIPOR2	116	Q9Y4F9
YIDQRKTIKTMLEYA	SCN1A	1241	P35498
YLQMARKKARESYVE	CLTC	1156	Q00610
AKQVELMRDYRIKYP	CHSY1	581	Q86X52
YYRKRTIQLEAKMRI	CLHC1	111	Q8NHS4
LESIMDKAYIYRVIR	CNGB3	341	Q9NQW8
RYNRRKYSEIMAEKA	DNTTIP2	726	Q5QJE6
EADEYYRKKLLIQMK	TRIM77	131	I1YAP6
YLYQKIMFGKRRKIR	PES1	546	O00541
RDSMKVLYYVEKELA	ILDR2	306	Q71H61
NRYLEVMRKLQKTYR	PTPA	221	Q15257
YIEQRKTIKTMLEYA	SCN2A	1231	Q99250
LYRKMKLRYPINEEA	PLCG1	746	P19174
RIKEIQYEIFRSLMY	TENM3	2086	Q9P273
YRIMYKKRTKRLVVF	POLR2K	41	P53803
RYMYRSKELIRNKRE	USP28	396	Q96RU2
IKRQLVDYEEKYGRM	VPS53	291	Q5VIR6
RVVKLMYKNRLYFRS	PLEKHH1	1086	Q9ULM0
KEERSSYLEYQKVMR	SMC2	211	O95347
IKRMYEKEQLREYVE	SYMPK	736	Q92797
RKLYKEVMLETFRNL	ZNF69	46	Q9UC07
IYMDQRKTIKILLEY	SCN7A	956	Q01118
ERKNAEYKRYLEMLL	SF3A3	176	Q12874
VQTQRLKIMEYYEKK	ATP6V1E1	46	P36543
KLYEFRRGMKRYVTI	WIPI1	221	Q5MNZ9
MLAIQIKYDDYKIRL	XKRX	221	Q6PP77
LKRTKMVRTINLYYN	UBR4	3581	Q5T4S7
AKDPRYARYLKMVQV	WASHC3	131	Q9Y3C0
EFLVRENRKYYMDLK	PURA	146	Q00577
DREARQKKMYYLRTE	ZNF318	901	Q5VUA4
YRKVMLENYRSLVSL	ZNF583	31	Q96ND8
TRYQQIMKRLIKRYV	TRPC3	761	Q13507
VQTQRLKIMEYYEKK	ATP6V1E2	46	Q96A05
LRNMQDLVEDYKKRY	KRT72	201	Q14CN4
LRSMRDLVEDYKKRY	KRT74	216	Q7RTS7
LMVLYKDKVYNIQIR	LCP2	461	Q13094
MRYKRTKAALTIIRY	MYO1D	716	O94832