Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A18 MFSD2A SLC8A2 SLC8A1 ABCA4 ATP8A1 ABCA13 SLC19A1 SURF1 COX6B1 SLC35E1 CTNS

4.78e-074778112GO:0022804
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A18 MFSD2A SLC8A2 SLC8A1 ATP8A1 SLC19A1 SURF1 COX6B1 CTNS

3.60e-06301819GO:0022853
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

MFSD2A ABCA4 ATP8A1

2.27e-0514813GO:0140333
GeneOntologyMolecularFunctionflippase activity

MFSD2A ABCA4 ATP8A1

4.20e-0517813GO:0140327
GeneOntologyMolecularFunctionglucose-6-phosphatase activity

G6PC2 G6PC1

4.86e-053812GO:0004346
GeneOntologyMolecularFunctionsugar-terminal-phosphatase activity

G6PC2 G6PC1

4.86e-053812GO:0050309
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

SLC8A2 SLC8A1

4.86e-053812GO:1905060
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC6A18 MFSD14A MFSD2A SLC8A2 SLC8A1 ABCA4 ATP8A1 PSG5 ABCA13 SLC19A1 SURF1 COX6B1 SLC35E1 CTNS CNGA4

7.01e-0511808115GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC6A18 MFSD14A MFSD2A SLC8A2 SLC8A1 ABCA4 ATP8A1 PSG5 ABCA13 SLC19A1 SURF1 COX6B1 SLC35E1 CTNS CNGA4

1.87e-0412898115GO:0005215
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

MFSD2A ABCA4 ATP8A1

1.96e-0428813GO:0140326
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A18 MFSD2A SLC8A2 SLC8A1 SLC19A1 SLC35E1 CTNS

2.00e-04296817GO:0015291
GeneOntologyMolecularFunctionG protein-coupled acetylcholine receptor activity

CHRM2 CHRM4

3.37e-047812GO:0016907
GeneOntologyMolecularFunctioncalcium:sodium antiporter activity

SLC8A2 SLC8A1

7.16e-0410812GO:0005432
GeneOntologyMolecularFunctionsugar-phosphatase activity

G6PC2 G6PC1

7.16e-0410812GO:0050308
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA4 ATP8A1 ABCA13 SURF1 COX6B1

7.89e-04178815GO:0015399
GeneOntologyMolecularFunctioncarbohydrate phosphatase activity

G6PC2 G6PC1

8.73e-0411812GO:0019203
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

MFSD2A ABCA4 ATP8A1

1.16e-0351813GO:0140303
GeneOntologyMolecularFunctionlipid transporter activity

MFSD2A ABCA4 ATP8A1 PSG5 ABCA13

1.21e-03196815GO:0005319
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity

SLC8A2 SLC8A1

1.23e-0313812GO:0015368
GeneOntologyMolecularFunctioncytidine deaminase activity

APOBEC3D APOBEC3C

1.23e-0313812GO:0004126
GeneOntologyMolecularFunctionG protein-coupled neurotransmitter receptor activity

CHRM2 CHRM4

1.23e-0313812GO:0099528
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC6A18 MFSD2A SLC8A2 SLC8A1 ATP8A1 SLC19A1 SURF1 COX6B1 CTNS CNGA4

1.35e-037938110GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC6A18 MFSD2A SLC8A2 SLC8A1 ATP8A1 SURF1 COX6B1 CTNS CNGA4

1.45e-03664819GO:0008324
GeneOntologyMolecularFunctioncytochrome-c oxidase activity

SURF1 COX6B1

1.88e-0316812GO:0004129
GeneOntologyMolecularFunctionadenylate cyclase binding

ADCY5 ADCYAP1R1

1.88e-0316812GO:0008179
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRH PTPRO

2.12e-0317812GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRH PTPRO

2.12e-0317812GO:0019198
GeneOntologyMolecularFunctionoxidoreductase activity, acting on a heme group of donors

SURF1 COX6B1

2.38e-0318812GO:0016675
GeneOntologyMolecularFunctionantiporter activity

SLC8A2 SLC8A1 SLC19A1 SLC35E1

2.41e-03138814GO:0015297
GeneOntologyMolecularFunctionRNA cap binding

IFIT5 NCBP1

3.25e-0321812GO:0000339
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

MFSD2A ABCA4 PSG5

3.26e-0373813GO:0170055
GeneOntologyMolecularFunctionphospholipid transporter activity

MFSD2A ABCA4 ATP8A1

3.39e-0374813GO:0005548
GeneOntologyMolecularFunctionG protein-coupled serotonin receptor activity

CHRM2 CHRM4

3.56e-0322812GO:0004993
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC6A18 MFSD2A SLC8A2 SLC8A1 SURF1 COX6B1 CTNS CNGA4

3.88e-03627818GO:0022890
GeneOntologyMolecularFunctionacetylcholine receptor activity

CHRM2 CHRM4

3.89e-0323812GO:0015464
GeneOntologyMolecularFunctionphosphatidylinositol-5-phosphate binding

JPH2 RS1

3.89e-0323812GO:0010314
GeneOntologyMolecularFunctionvirus receptor activity

ACE2 DPP4 EGFR

5.00e-0385813GO:0001618
GeneOntologyMolecularFunctionexogenous protein binding

ACE2 DPP4 EGFR

5.17e-0386813GO:0140272
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC6A18 MFSD2A SLC8A2 SLC8A1

5.18e-03171814GO:0015081
GeneOntologyMolecularFunctionmannosyltransferase activity

ALG8 ALG12

5.74e-0328812GO:0000030
GeneOntologyBiologicalProcessdefense response to virus

APOBEC3D IFIT5 NCBP1 APOBEC3C UNC93B1 PQBP1 IFIT2 LYST IFIT3 CARD8

1.02e-063428210GO:0051607
GeneOntologyBiologicalProcessresponse to virus

APOBEC3D IFIT5 NCBP1 APOBEC3C UNC93B1 PQBP1 IFIT2 LYST IFIT3 CARD8

7.07e-064258210GO:0009615
GeneOntologyBiologicalProcessreceptor-mediated endocytosis of virus by host cell

ACE2 DPP4 KIAA0319L

1.30e-0512823GO:0019065
GeneOntologyBiologicalProcessendocytosis involved in viral entry into host cell

ACE2 DPP4 KIAA0319L

2.14e-0514823GO:0075509
GeneOntologyBiologicalProcesscalcium ion transport into cytosol

SLC8A2 SLC8A1 JPH2 ADCYAP1R1

2.31e-0542824GO:0060402
GeneOntologyBiologicalProcessvascular process in circulatory system

ACE2 MFSD2A SLC8A2 SLC8A1 ATP8A1 EGFR PSG5 SLC19A1

6.73e-05344828GO:0003018
GeneOntologyBiologicalProcessdefense response to other organism

DPP4 APOBEC3D PSG5 SLC19A1 SCD TAX1BP1 IFIT5 NCBP1 APOBEC3C UNC93B1 PQBP1 IFIT2 PGC LYST IFIT3 CARD8

1.15e-0414078216GO:0098542
GeneOntologyBiologicalProcesstransport of virus

ACE2 DPP4 KIAA0319L

1.15e-0424823GO:0046794
GeneOntologyBiologicalProcessdefense response to symbiont

DPP4 APOBEC3D PSG5 SLC19A1 TAX1BP1 IFIT5 NCBP1 APOBEC3C UNC93B1 PQBP1 IFIT2 PGC LYST IFIT3 CARD8

1.47e-0412868215GO:0140546
GeneOntologyBiologicalProcesscirculatory system process

EPHX2 ACE2 MFSD2A SLC8A2 SLC8A1 ATP8A1 EGFR PTPRO PSG5 SLC19A1 CHRM2

1.49e-047338211GO:0003013
GeneOntologyBiologicalProcessregulation of cardiac conduction

ACE2 SLC8A2 SLC8A1

2.05e-0429823GO:1903779
GeneOntologyBiologicalProcessreceptor-mediated virion attachment to host cell

ACE2 DPP4

2.32e-046822GO:0046813
GeneOntologyBiologicalProcessclearance of foreign intracellular DNA

APOBEC3D APOBEC3C

2.32e-046822GO:0044355
GeneOntologyBiologicalProcessclearance of foreign intracellular nucleic acids

APOBEC3D APOBEC3C

2.32e-046822GO:0099046
GeneOntologyBiologicalProcesscarbohydrate derivative metabolic process

ATPSCKMT SPAM1 APOBEC3D FBXO6 ICMT ALG8 FUCA1 APOBEC3C CTNS G6PC2 G6PC1 ALG12 ADCY5 STT3B

3.14e-0412268214GO:1901135
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC6A18 ATPSCKMT SLC8A2 SLC8A1 ATP8A1 SURF1 COX6B1 JPH2 NIPSNAP2 CTNS CNGA4 ADCYAP1R1

3.33e-049428212GO:0098655
GeneOntologyBiologicalProcessinnate immune response

DPP4 APOBEC3D PSG5 SLC19A1 TAX1BP1 IFIT5 APOBEC3C UNC93B1 PQBP1 IFIT2 LYST IFIT3 CARD8

3.55e-0410928213GO:0045087
GeneOntologyBiologicalProcesstransport across blood-brain barrier

MFSD2A SLC8A2 ATP8A1 SLC19A1

4.02e-0487824GO:0150104
GeneOntologyBiologicalProcessviral life cycle

ACE2 DPP4 APOBEC3D EGFR KIAA0319L IFIT5 APOBEC3C

4.10e-04340827GO:0019058
GeneOntologyBiologicalProcessvascular transport

MFSD2A SLC8A2 ATP8A1 SLC19A1

4.20e-0488824GO:0010232
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

CHRM2 CHRM4

4.30e-048822GO:0007197
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC6A18 ATPSCKMT SLC8A2 SLC8A1 ATP8A1 SLC19A1 SURF1 COX6B1 JPH2 NIPSNAP2 CTNS CNGA4 ADCYAP1R1

4.33e-0411158213GO:0034220
GeneOntologyBiologicalProcessorganophosphate ester transport

MFSD2A ABCA4 ATP8A1 SLC19A1 G6PC1

4.71e-04162825GO:0015748
GeneOntologyBiologicalProcessvirion attachment to host cell

ACE2 DPP4

5.52e-049822GO:0019062
GeneOntologyBiologicalProcessglycosyl compound catabolic process

APOBEC3D FUCA1 APOBEC3C

5.79e-0441823GO:1901658
GeneOntologyBiologicalProcessglycosyl compound metabolic process

APOBEC3D ICMT FUCA1 APOBEC3C

5.84e-0496824GO:1901657
GeneOntologyCellularComponentsymmetric synapse

MKLN1 IGSF9B CHRM2

1.56e-0513813GO:0032280
GeneOntologyCellularComponentcell projection membrane

SLC6A18 ACE2 DPP4 PTPRH EGFR PSG5 SLC19A1 IFIT5 CNGA4

4.35e-05431819GO:0031253
GeneOntologyCellularComponentpostsynaptic specialization of symmetric synapse

MKLN1 IGSF9B

8.85e-054812GO:0099629
GeneOntologyCellularComponentapical part of cell

SLC6A18 ACE2 DPP4 DUOX1 PTPRH EGFR PTPRO PSG5 SLC19A1 IFIT5

9.48e-055928110GO:0045177
GeneOntologyCellularComponentapical plasma membrane

SLC6A18 ACE2 DPP4 DUOX1 PTPRH EGFR PTPRO PSG5 SLC19A1

1.11e-04487819GO:0016324
GeneOntologyCellularComponentpostsynaptic membrane

SLC8A2 SLC8A1 PTPRO MKLN1 APBB1 IGSF9B CHRM2 CHRM4

1.73e-04405818GO:0045211
GeneOntologyCellularComponentneuron to neuron synapse

SLC8A2 ZDHHC15 SLC8A1 PTPRO MKLN1 IGSF9B RS1 CHRM2 CHRM4

1.89e-04523819GO:0098984
GeneOntologyCellularComponentendoplasmic reticulum membrane

MFSD2A MBTPS1 EGFR ICMT SCD MACO1 JPH2 ALG8 UNC93B1 G6PC2 G6PC1 ALG12 STT3B

1.34e-0312938113GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

MFSD2A MBTPS1 EGFR ICMT SCD MACO1 JPH2 ALG8 UNC93B1 G6PC2 G6PC1 ALG12 STT3B

1.40e-0312998113GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

MFSD2A MBTPS1 EGFR ICMT SCD MACO1 JPH2 ALG8 UNC93B1 G6PC2 G6PC1 ALG12 STT3B

1.69e-0313278113GO:0042175
GeneOntologyCellularComponentsynaptic membrane

SLC8A2 SLC8A1 PTPRO MKLN1 APBB1 IGSF9B CHRM2 CHRM4

1.88e-03583818GO:0097060
GeneOntologyCellularComponentneuron projection terminus

SLC8A2 SLC8A1 MACO1 CHRM2 CHRM4

2.12e-03233815GO:0044306
HumanPhenoHyponatremia

ALG8 UNC93B1 CTNS LYST ALG12

1.53e-0560285HP:0002902
HumanPhenoAbnormal blood sodium concentration

ALG8 UNC93B1 CTNS LYST ALG12

3.74e-0572285HP:0010931
HumanPhenoDeath in childhood

MFSD2A SURF1 JPH2 PQBP1 ADCY5 STT3B

6.10e-05131286HP:0003819
MousePhenoabnormal susceptibility to viral infection

ACE2 DPP4 MBTPS1 APOBEC3D EGFR PSG5 KIAA0319L UNC93B1 IFIT2 LYST

5.00e-072796410MP:0020185
MousePhenopigmentation phenotype

ACE2 MFSD2A MBTPS1 ABCA4 EGFR NTRK1 RBPMS2 KIAA0319L MKLN1 ALG8 FUCA1 CTNS RS1 LYST

6.52e-076246414MP:0001186
MousePhenoincreased susceptibility to viral infection

ACE2 DPP4 MBTPS1 APOBEC3D EGFR UNC93B1 IFIT2 LYST

1.10e-06172648MP:0002418
MousePhenopulmonary hyaline membrane formation

ACE2 DPP4

2.06e-052642MP:0011018
MousePhenoabnormal susceptibility to pulmonary hyaline membrane formation

ACE2 DPP4

2.06e-052642MP:0031106
MousePhenoincreased susceptibility to pulmonary hyaline membrane formation

ACE2 DPP4

2.06e-052642MP:0012041
MousePhenoabnormal susceptibility to infection

ACE2 DPP4 MBTPS1 APOBEC3D EGFR PSG5 SCD KIAA0319L UNC93B1 IFIT2 LYST ADCYAP1R1

4.54e-056726412MP:0001793
MousePhenoabnormal susceptibility to Coronaviridae infection

ACE2 DPP4 EGFR PSG5

7.25e-0549644MP:0020948
MousePhenoabnormal response to infection

ACE2 DPP4 MBTPS1 APOBEC3D EGFR PSG5 SCD KIAA0319L UNC93B1 IFIT2 LYST ADCYAP1R1

8.15e-057146412MP:0005025
MousePhenoincreased susceptibility to infection

ACE2 DPP4 MBTPS1 APOBEC3D EGFR SCD UNC93B1 IFIT2 LYST ADCYAP1R1

8.93e-055046410MP:0002406
MousePhenoabnormal response to antigen

ACE2 DPP4 MBTPS1 APOBEC3D EGFR PSG5 SCD KIAA0319L UNC93B1 IFIT2 LYST ADCYAP1R1

9.55e-057266412MP:0020000
MousePhenoincreased susceptibility to Riboviria infection induced morbidity/mortality

ACE2 DPP4 EGFR IFIT2

1.23e-0456644MP:0031024
MousePhenodecreased susceptibility to infection

ACE2 DPP4 MBTPS1 APOBEC3D PSG5 KIAA0319L LYST

1.58e-04255647MP:0002409
MousePhenoincreased susceptibility to Coronaviridae infection

ACE2 DPP4 EGFR

1.73e-0424643MP:0020949
MousePhenodecreased susceptibility to viral infection

ACE2 DPP4 APOBEC3D PSG5 KIAA0319L

2.64e-04125645MP:0002410
MousePhenodecreased susceptibility to Coronaviridae infection

ACE2 DPP4 PSG5

2.76e-0428643MP:0020950
MousePhenoabnormal retina pigment epithelium morphology

MFSD2A ABCA4 CTNS RS1 LYST

3.77e-04135645MP:0005201
MousePhenoincreased susceptibility to viral infection induced morbidity/mortality

ACE2 DPP4 EGFR IFIT2

4.21e-0477644MP:0009791
MousePhenoimpaired smooth muscle contractility

SLC8A1 CHRM2 CHRM4

5.40e-0435643MP:0000740
MousePhenoincreased left ventricle systolic pressure

SLC8A1 EGFR

5.68e-048642MP:0003820
DomainNa_Ca_Ex

SLC8A2 SLC8A1

5.15e-053782IPR004836
DomainNa_Ca_Ex_C-exten

SLC8A2 SLC8A1

5.15e-053782IPR032452
DomainGlucose-6-phosphatase

G6PC2 G6PC1

5.15e-053782IPR016275
DomainNa_Ca_ex_C

SLC8A2 SLC8A1

5.15e-053782PF16494
DomainPecanex_C

PCNX3 PCNX1

1.03e-044782PF05041
DomainPecanex

PCNX3 PCNX1

1.03e-044782IPR007735
DomainMusac_Ach_rcpt

CHRM2 CHRM4

1.71e-045782IPR000995
DomainCalx_beta

SLC8A2 SLC8A1

4.74e-048782SM00237
DomainCalx_beta

SLC8A2 SLC8A1

6.08e-049782IPR003644
DomainNaCa_Exmemb

SLC8A2 SLC8A1

6.08e-049782IPR004837
DomainNa_Ca_ex

SLC8A2 SLC8A1

6.08e-049782PF01699
DomainPKD/Chitinase_dom

KIAA0319L SORCS1

6.08e-049782IPR022409
DomainPKD

KIAA0319L SORCS1

6.08e-049782SM00089
DomainCalx-beta

SLC8A2 SLC8A1

6.08e-049782PF03160
DomainPKD

KIAA0319L SORCS1

9.24e-0411782PS50093
DomainPKD_dom

KIAA0319L SORCS1

9.24e-0411782IPR000601
Domain-

KIAA0319L SORCS1

9.24e-04117822.60.40.670
DomainAPOBEC_N

APOBEC3D APOBEC3C

1.11e-0312782PF08210
DomainABC_A

ABCA4 ABCA13

1.11e-0312782IPR026082
DomainAPOBEC_N

APOBEC3D APOBEC3C

1.11e-0312782IPR013158
DomainTPR_2

IFIT5 IFIT2 IFIT3

1.19e-0350783PF07719
DomainTPR_2

IFIT5 IFIT2 IFIT3

1.19e-0350783IPR013105
DomainTPR_8

IFIT5 IFIT2 IFIT3

1.41e-0353783PF13181
DomainAPOBEC/CMP_deaminase_Zn-bd

APOBEC3D APOBEC3C

1.52e-0314782IPR016192
DomainCytidine_deaminase-like

APOBEC3D APOBEC3C

2.25e-0317782IPR016193
DomainCYT_DCMP_DEAMINASES_1

APOBEC3D APOBEC3C

2.25e-0317782PS00903
DomainCMP_dCMP_Zn-bd

APOBEC3D APOBEC3C

2.25e-0317782IPR002125
Domain-

G6PC2 G6PC1

2.52e-03187821.20.144.10
DomainacidPPc

G6PC2 G6PC1

2.52e-0318782SM00014
DomainP_Acid_Pase_2/haloperoxidase

G6PC2 G6PC1

3.12e-0320782IPR000326
DomainPAP2

G6PC2 G6PC1

3.12e-0320782PF01569
Domain-

FBXO6 MKLN1 RS1

3.53e-03737832.60.120.260
DomainTPR_1

IFIT5 IFIT2 IFIT3

6.34e-0390783PF00515
DomainTPR_1

IFIT5 IFIT2 IFIT3

6.34e-0390783IPR001440
DomainGalactose-bd-like

FBXO6 MKLN1 RS1

7.15e-0394783IPR008979
DomainFN3

PTPRH PTPRO KIAA0319L IGSF9B

7.52e-03185784SM00060
Pubmed

Comprehensive analysis of the prognosis and biological significance for IFIT family in skin cutaneous melanoma.

IFIT5 IFIT2 IFIT3

5.04e-08482334763233
Pubmed

The broad-spectrum antiviral functions of IFIT and IFITM proteins.

IFIT5 IFIT2 IFIT3

2.51e-07682323237964
Pubmed

A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2.

ACE2 DPP4

5.49e-06282233218025
Pubmed

Targeting DPP4-RBD interactions by sitagliptin and linagliptin delivers a potential host-directed therapy against pan-SARS-CoV-2 infections.

ACE2 DPP4

5.49e-06282237385308
Pubmed

Loss of muscarinic autoreceptor function impairs long-term depression but not long-term potentiation in the striatum.

CHRM2 CHRM4

5.49e-06282218550768
Pubmed

Muscarinic agonist-mediated increases in serum corticosterone levels are abolished in m(2) muscarinic acetylcholine receptor knockout mice.

CHRM2 CHRM4

5.49e-06282212235238
Pubmed

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.

ACE2 DPP4

5.49e-06282223831647
Pubmed

Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets.

ACE2 DPP4

5.49e-06282233597220
Pubmed

Modified expression of peripheral blood lymphocyte muscarinic cholinergic receptors in asthmatic children.

CHRM2 CHRM4

5.49e-06282226025056
Pubmed

Roles of Na(+)/Ca(2+) exchanger isoforms NCX1 and NCX2 in motility in mouse ileum.

SLC8A2 SLC8A1

5.49e-06282227411318
Pubmed

Na+/Ca2+ exchanger contributes to stool transport in mice with experimental diarrhea.

SLC8A2 SLC8A1

5.49e-06282227928109
Pubmed

Striatal muscarinic receptors promote activity dependence of dopamine transmission via distinct receptor subtypes on cholinergic interneurons in ventral versus dorsal striatum.

CHRM2 CHRM4

5.49e-06282220203199
Pubmed

Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice.

CHRM2 CHRM4

5.49e-06282212391271
Pubmed

Phage-Displayed Mimotopes of SARS-CoV-2 Spike Protein Targeted to Authentic and Alternative Cellular Receptors.

ACE2 DPP4

5.49e-06282235215976
Pubmed

Generation and pharmacological analysis of M2 and M4 muscarinic receptor knockout mice.

CHRM2 CHRM4

5.49e-06282211392613
Pubmed

Characterization of the novel positive allosteric modulator, LY2119620, at the muscarinic M(2) and M(4) receptors.

CHRM2 CHRM4

5.49e-06282224807965
Pubmed

Development of a radioligand, [(3)H]LY2119620, to probe the human M(2) and M(4) muscarinic receptor allosteric binding sites.

CHRM2 CHRM4

5.49e-06282224807966
Pubmed

Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes.

G6PC2 G6PC1

5.49e-06282211297555
Pubmed

Genetic knockout and pharmacologic inhibition of NCX2 cause natriuresis and hypercalciuria.

SLC8A2 SLC8A1

5.49e-06282225498502
Pubmed

Stearoyl-CoA desaturase activity modulates the activation of epidermal growth factor receptor in human lung cancer cells.

EGFR SCD

5.49e-06282222946088
Pubmed

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses.

ACE2 DPP4

5.49e-06282232094589
Pubmed

Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice.

CHRM2 CHRM4

5.49e-06282212874603
Pubmed

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2.

ACE2 DPP4

5.49e-06282232275855
Pubmed

Muscarinic M2 receptors on peripheral nerve endings: a molecular target of antinociception.

CHRM2 CHRM4

5.49e-06282212045234
Pubmed

Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice.

CHRM2 CHRM4

5.49e-06282216365281
Pubmed

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

ACE2 DPP4

5.49e-06282232375025
Pubmed

The lethal internal face of the coronaviruses: Kidney tropism of the SARS, MERS, and COVID19 viruses.

ACE2 DPP4

5.49e-06282234118117
Pubmed

Na(+) /Ca(2+) exchanger-heterozygote knockout mice display increased relaxation in gastric fundus and accelerated gastric transit in vivo.

SLC8A2 SLC8A1

5.49e-06282226787195
Pubmed

M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro.

CHRM2 CHRM4

5.49e-06282210688600
Pubmed

Elevated phosphorylation of EGFR in NSCLC due to mutations in PTPRH.

PTPRH EGFR

5.49e-06282236054194
Pubmed

The Firing of Theta State-Related Septal Cholinergic Neurons Disrupt Hippocampal Ripple Oscillations via Muscarinic Receptors.

CHRM2 CHRM4

5.49e-06282232265261
Pubmed

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine.

ACE2 DPP4

5.49e-06282232203189
Pubmed

Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.

CHRM2 CHRM4

5.49e-06282211880500
Pubmed

Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses.

DPP4 EGFR

5.49e-06282230134935
Pubmed

A genetic variant of G6PC2 is associated with type 2 diabetes and fasting plasma glucose level in the Chinese population.

G6PC2 G6PC1

5.49e-06282219082990
Pubmed

Putative Receptor Binding Domain of Bat-Derived Coronavirus HKU9 Spike Protein: Evolution of Betacoronavirus Receptor Binding Motifs.

ACE2 DPP4

5.49e-06282227696819
Pubmed

Intronic variant of EGFR is associated with GBAS expression and survival outcome of early-stage non-small cell lung cancer.

EGFR NIPSNAP2

5.49e-06282229806744
Pubmed

Knockouts reveal overlapping functions of M(2) and M(4) muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus.

CHRM2 CHRM4

5.49e-06282222956788
Pubmed

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.

ACE2 DPP4

5.49e-06282223486063
Pubmed

Effects of induced Na+/Ca2+ exchanger overexpression on the spatial distribution of L-type Ca2+ channels and junctophilin-2 in pressure-overloaded hearts.

SLC8A1 JPH2

5.49e-06282227789286
Pubmed

HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages.

APOBEC3C IFIT2 IFIT3

5.63e-061582325170834
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

FAM171A2 EGFR SLC19A1 SCD KIAA0319L SLC35E1 APBB1 STT3B

1.49e-0546782830194290
Pubmed

The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling.

DUOX1 EGFR

1.64e-05382227650496
Pubmed

G6PC indicated poor prognosis in cervical cancer and promoted cervical carcinogenesis in vitro and in vivo.

G6PC2 G6PC1

1.64e-05382235277194
Pubmed

Muscarinic M2 receptors mediate transactivation of EGF receptor through Fyn kinase and without matrix metalloproteases.

EGFR CHRM2

1.64e-05382216337776
Pubmed

Functional annotation of heart enriched mitochondrial genes GBAS and CHCHD10 through guilt by association.

SURF1 NIPSNAP2

1.64e-05382220888800
Pubmed

Epidermal growth factor-induced hydrogen peroxide production is mediated by dual oxidase 1.

DUOX1 EGFR

1.64e-05382227262981
Pubmed

Expression analysis of miRNA hsa-let7b-5p in naso-oropharyngeal swabs of COVID-19 patients supports its role in regulating ACE2 and DPP4 receptors.

ACE2 DPP4

1.64e-05382236073344
Pubmed

The APOBEC3C crystal structure and the interface for HIV-1 Vif binding.

APOBEC3D APOBEC3C

1.64e-05382223001005
Pubmed

Nerve growth factor (NGF)-TrkA axis in head and neck squamous cell carcinoma triggers EMT and confers resistance to the EGFR inhibitor erlotinib.

EGFR NTRK1

1.64e-05382231838083
Pubmed

The interferon stimulated gene 54 promotes apoptosis.

IFIT2 IFIT3

1.64e-05382221190939
Pubmed

Effects of muscarinic receptor antagonists on cocaine discrimination in wild-type mice and in muscarinic receptor M1, M2, and M4 receptor knockout mice.

CHRM2 CHRM4

1.64e-05382228442355
Pubmed

G6PC1 and G6PC2 influence G6P flux but not HSD11B1 activity.

G6PC2 G6PC1

1.64e-05382237855366
Pubmed

High levels of synaptosomal Na(+)-Ca(2+) exchangers (NCX1, NCX2, NCX3) co-localized with amyloid-beta in human cerebral cortex affected by Alzheimer's disease.

SLC8A2 SLC8A1

1.64e-05382221382638
Pubmed

Group II muscarinic acetylcholine receptors attenuate hepatic injury via Nrf2/ARE pathway.

CHRM2 CHRM4

1.64e-05382232234387
Pubmed

M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: Findings obtained with muscarinic-receptor knockout mouse.

CHRM2 CHRM4

1.64e-05382217008557
Pubmed

Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.

IFIT2 IFIT3

1.64e-05382226423178
Pubmed

Molecular cloning and characterization of a murine LPS-inducible cDNA.

IFIT2 IFIT3

1.64e-0538228207206
Pubmed

The downregulation of NCXs is positively correlated with the prognosis of stage II-IV colon cancer.

SLC8A2 SLC8A1

1.64e-05382234127021
Pubmed

Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3.

SLC6A18 ACE2

1.64e-05382219478081
Pubmed

GRK5 deficiency leads to reduced hippocampal acetylcholine level via impaired presynaptic M2/M4 autoreceptor desensitization.

CHRM2 CHRM4

1.64e-05382219478075
Pubmed

Characterization of the phosphotyrosine-binding domain of the Drosophila Shc protein.

EGFR NTRK1

1.64e-0538228943228
Pubmed

PACAP through EGFR transactivation preserves human corneal endothelial integrity.

EGFR ADCYAP1R1

1.64e-05382230548314
Pubmed

Genetic deletion of CB1 receptors improves non-associative learning.

CHRM2 CHRM4

1.64e-05382215922076
Pubmed

Dual oxidase-1 is required for airway epithelial cell migration and bronchiolar reepithelialization after injury.

DUOX1 EGFR

1.64e-05382223239498
Pubmed

Structure-Dynamic Coupling Through Ca2+-Binding Regulatory Domains of Mammalian NCX Isoform/Splice Variants.

SLC8A2 SLC8A1

1.64e-05382229594857
Pubmed

Assignment of muscarinic receptor subtypes mediating G-protein modulation of Ca(2+) channels by using knockout mice.

CHRM2 CHRM4

1.64e-05382210485923
Pubmed

EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer.

EGFR SCD

1.64e-05382228724430
Pubmed

IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA.

IFIT2 IFIT3

1.64e-05382229554348
Pubmed

Distribution of ACE2, CD147, CD26, and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors.

ACE2 DPP4

1.64e-05382232496587
Pubmed

Muscarinic receptor knockout mice: role of muscarinic acetylcholine receptors M(2), M(3), and M(4) in carbamylcholine-induced gallbladder contractility.

CHRM2 CHRM4

1.64e-05382211961069
Pubmed

SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells.

ACE2 DPP4

1.64e-05382234903715
Pubmed

Identification of specific determinants of human APOBEC3F, APOBEC3C, and APOBEC3DE and African green monkey APOBEC3F that interact with HIV-1 Vif.

APOBEC3D APOBEC3C

1.64e-05382220943965
Pubmed

A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.

EGFR NTRK1

1.64e-0538227542991
Pubmed

Aberrant Amygdala-Dependent Cued Fear Memory in Na+/Ca2+ Exchanger 1 Heterozygous Mice.

SLC8A2 SLC8A1

1.64e-05382230324228
Pubmed

Sodium-calcium exchange in intracellular calcium handling of human airway smooth muscle.

SLC8A2 SLC8A1

1.64e-05382221858195
Pubmed

Intact coupling of M1 receptors and preserved M2 and M4 receptors in the cortex in progressive supranuclear palsy: contrast with other dementias.

CHRM2 CHRM4

1.64e-05382218282687
Pubmed

IFIT1 and IFIT3 promote oral squamous cell carcinoma metastasis and contribute to the anti-tumor effect of gefitinib via enhancing p-EGFR recycling.

EGFR IFIT3

1.64e-05382230626937
Pubmed

Knowledge-based analysis of functional impacts of mutations in microRNA seed regions.

EGFR NTRK1

1.64e-05382226564979
Pubmed

Paradoxical sleep in mice lacking M3 and M2/M4 muscarinic receptors.

CHRM2 CHRM4

1.64e-05382216110248
Pubmed

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.

EGFR NTRK1

1.64e-0538228577769
Pubmed

Complement opsonization of HIV-1 results in decreased antiviral and inflammatory responses in immature dendritic cells via CR3.

IFIT2 IFIT3

1.64e-05382225252956
Pubmed

Control of glycinergic input to spinal dorsal horn neurons by distinct muscarinic receptor subtypes revealed using knockout mice.

CHRM2 CHRM4

1.64e-05382217878406
Pubmed

Immunosuppressive drugs, immunophilins, and functional expression of NCX isoforms.

SLC8A2 SLC8A1

1.64e-05382223224887
Pubmed

New roles of NCX in glial cells: activation of microglia in ischemia and differentiation of oligodendrocytes.

SLC8A2 SLC8A1

1.64e-05382223224890
Pubmed

Genetically modified mice as a strategy to unravel the role played by the Na(+)/Ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits.

SLC8A2 SLC8A1

1.64e-05382223224882
Pubmed

Three Na+/Ca2+ exchanger (NCX) variants are expressed in mouse osteoclasts and mediate calcium transport during bone resorption.

SLC8A2 SLC8A1

1.64e-05382217317768
Pubmed

Distinct mixtures of muscarinic receptor subtypes mediate inhibition of noradrenaline release in different mouse peripheral tissues, as studied with receptor knockout mice.

CHRM2 CHRM4

1.64e-05382215965496
Pubmed

Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy.

IFIT2 IFIT3

1.64e-05382234884921
Pubmed

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.

EGFR NTRK1

1.64e-05382228591715
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

APOBEC3D TAX1BP1 HELZ2 APOBEC3C IFIT2 IFIT3

1.72e-0522882630471916
Pubmed

Ultrasonic vocalizations induced by sex and amphetamine in M2, M4, M5 muscarinic and D2 dopamine receptor knockout mice.

CHRM2 CHRM4

3.28e-05482218382674
Pubmed

Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins.

APOBEC3D APOBEC3C

3.28e-05482219088851
Pubmed

Importance of K+-dependent Na+/Ca2+-exchanger 2, NCKX2, in motor learning and memory.

SLC8A2 SLC8A1

3.28e-05482216407245
Pubmed

Expression of PTPRO during mouse development suggests involvement in axonogenesis and differentiation of NT-3 and NGF-dependent neurons.

PTPRO NTRK1

3.28e-05482212532410
Pubmed

Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice.

SLC8A2 SLC8A1

3.28e-05482229274751
Pubmed

Coordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses.

IFIT2 IFIT3

3.28e-05482217079283
Pubmed

Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes.

CHRM2 CHRM4

3.28e-0548222739737
Pubmed

Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs.

IFIT2 IFIT3

3.28e-0548229391139
Pubmed

A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G.

APOBEC3D APOBEC3C

3.28e-05482219535450
InteractionDDOST interactions

ACE2 DPP4 FBXO6 PTPRH EGFR PTPRO SCD NTRK1 APBB1 UNC93B1 STT3B

2.33e-073757911int:DDOST
InteractionALG1 interactions

ACE2 DPP4 FBXO6 EGFR NTRK1

2.22e-0654795int:ALG1
InteractionXPOT interactions

ACE2 DPP4 FBXO6 PTPRH EGFR PTPRO NTRK1 UNC93B1

2.38e-06220798int:XPOT
InteractionTFRC interactions

ACE2 DPP4 FBXO6 PTPRH EGFR PTPRO NTRK1 KIAA0319L APBB1 UNC93B1 ADCY5

3.13e-064897911int:TFRC
InteractionCANX interactions

ACE2 DPP4 MBTPS1 FBXO6 PTPRH EGFR HLA-DMB ICMT PTPRO SLC19A1 NTRK1 MACO1 KIAA0319L NIPSNAP2 APOBEC3C UNC93B1 STT3B

6.12e-0612617917int:CANX
InteractionGCN1 interactions

ACE2 FBXO6 PTPRH EGFR NTRK1 STK32B NCBP1 UNC93B1 CHRM4

8.95e-06349799int:GCN1
InteractionRPN2 interactions

ACE2 DPP4 ABCA4 FBXO6 EGFR PTPRO SCD NTRK1 MACO1 APBB1 ALG8 UNC93B1 STT3B

1.01e-057827913int:RPN2
InteractionGANAB interactions

ACE2 DPP4 ZDHHC15 FBXO6 PTPRH EGFR PTPRO NTRK1 NIPSNAP2

1.37e-05368799int:GANAB
InteractionHSD17B12 interactions

ACE2 DPP4 EGFR SCD NTRK1 TAX1BP1 UNC93B1

2.50e-05220797int:HSD17B12
InteractionCSE1L interactions

ACE2 DPP4 FBXO6 PTPRH EGFR NTRK1 UNC93B1 UBFD1

3.17e-05314798int:CSE1L
InteractionARL13B interactions

ACE2 ZDHHC15 FAM171A2 PTPRH EGFR ICMT APBB1 TMEM254

3.47e-05318798int:ARL13B
InteractionUGGT1 interactions

DPP4 FBXO6 PTPRH EGFR PTPRO NTRK1 UNC93B1

3.81e-05235797int:UGGT1
InteractionATP1B1 interactions

EGFR NTRK1 COX6B1 KIAA0319L NIPSNAP2 UNC93B1

4.99e-05167796int:ATP1B1
InteractionPTK7 interactions

ACE2 DPP4 FAM171A2 PTPRO NTRK1 APBB1

5.16e-05168796int:PTK7
InteractionDNAJB12 interactions

EGFR PTPRO NTRK1 UNC93B1 CNGA4 STT3B

6.27e-05174796int:DNAJB12
InteractionNUP210 interactions

DPP4 FBXO6 EGFR PTPRO NTRK1 UNC93B1

6.27e-05174796int:NUP210
InteractionTTC27 interactions

FBXO6 EGFR SCD NTRK1 UNC93B1

6.33e-05107795int:TTC27
InteractionCCDC47 interactions

DPP4 EGFR ICMT SCD NTRK1 MACO1 ALG8 UNC93B1 STT3B

6.35e-05448799int:CCDC47
InteractionCPD interactions

ACE2 DPP4 FBXO6 EGFR PTPRO NTRK1

6.47e-05175796int:CPD
InteractionSTT3B interactions

DPP4 FBXO6 SCD NTRK1 APBB1 UNC93B1 STT3B

6.54e-05256797int:STT3B
InteractionDNAJB11 interactions

ACE2 DPP4 FBXO6 PTPRH EGFR PTPRO NTRK1 STT3B

6.96e-05351798int:DNAJB11
InteractionDNAJC10 interactions

DPP4 FBXO6 EGFR PTPRO NTRK1 UNC93B1 STT3B

7.21e-05260797int:DNAJC10
InteractionSTT3A interactions

ACE2 FBXO6 EGFR NTRK1 UNC93B1 STT3B

7.34e-05179796int:STT3A
InteractionRPN1 interactions

ACE2 DPP4 FBXO6 EGFR ICMT SCD NTRK1 MACO1 APBB1 NIPSNAP2 UNC93B1 STT3B

7.39e-058147912int:RPN1
InteractionLANCL1 interactions

ACE2 DPP4 PTPRH EGFR NTRK1

7.87e-05112795int:LANCL1
InteractionMUC6 interactions

ZDHHC15 EGFR

9.06e-054792int:MUC6
InteractionCKAP4 interactions

ACE2 DPP4 PTPRH EGFR SCD NTRK1 MACO1 APBB1 UNC93B1 STT3B

1.03e-045927910int:CKAP4
InteractionSLC3A2 interactions

ACE2 DPP4 FBXO6 PTPRH EGFR PTPRO NTRK1 NIPSNAP2

1.04e-04372798int:SLC3A2
InteractionSDF2 interactions

DPP4 EGFR PTPRO ZER1

1.09e-0463794int:SDF2
InteractionPGRMC1 interactions

ACE2 DPP4 EGFR PTPRO SCD NIPSNAP2 UNC93B1 STT3B

1.10e-04375798int:PGRMC1
InteractionSNRPA interactions

ACE2 EGFR NTRK1 RBPMS2 NCBP1 APOBEC3C PQBP1 IFIT2 IFIT3

1.11e-04482799int:SNRPA
InteractionRAB5C interactions

ACE2 SLC19A1 NTRK1 MACO1 TAX1BP1 COX6B1 KIAA0319L SLC35E1 APBB1 STT3B

1.15e-046007910int:RAB5C
InteractionTM9SF2 interactions

ACE2 EGFR TAX1BP1 UNC93B1

1.23e-0465794int:TM9SF2
InteractionRAB11FIP1 interactions

ACE2 PTPRH EGFR NTRK1 TAX1BP1

1.32e-04125795int:RAB11FIP1
InteractionHLA-A interactions

ACE2 DPP4 EGFR PTPRO NTRK1 TAX1BP1 STK32B

1.39e-04289797int:HLA-A
InteractionOCLN interactions

ACE2 DPP4 FAM171A2 PCNX3 EGFR SLC19A1 APBB1 ZER1 PCNX1

1.46e-04500799int:OCLN
InteractionATP5PD interactions

DPP4 EGFR SURF1 TAX1BP1 COX6B1 NIPSNAP2 UNC93B1

1.58e-04295797int:ATP5PD
InteractionERO1A interactions

DPP4 FBXO6 EGFR PTPRO NTRK1

1.71e-04132795int:ERO1A
InteractionTTYH1 interactions

ATP8A1 PCNX3 SCD MACO1 ALG8 UNC93B1 ALG12

1.75e-04300797int:TTYH1
InteractionTELO2 interactions

ACE2 PTPRH EGFR NTRK1 UNC93B1

1.90e-04135795int:TELO2
InteractionATAD3B interactions

ACE2 DPP4 FBXO6 EGFR SURF1 NTRK1

1.90e-04213796int:ATAD3B
InteractionCOG7 interactions

EGFR NTRK1 TAX1BP1 UNC93B1

2.04e-0474794int:COG7
InteractionPBXIP1 interactions

ZDHHC15 DUOX1 NTRK1 MACO1 ALG8 UNC93B1

2.05e-04216796int:PBXIP1
InteractionISYNA1 interactions

ACE2 ATP8A1 EGFR NTRK1

2.15e-0475794int:ISYNA1
InteractionSPNS1 interactions

ACE2 EGFR NTRK1 UNC93B1

2.15e-0475794int:SPNS1
InteractionCDH2 interactions

ACE2 DPP4 FBXO6 EGFR NTRK1

2.17e-04139795int:CDH2
InteractionSLC5A9 interactions

EGFR NTRK1

2.25e-046792int:SLC5A9
InteractionNGLY1 interactions

FBXO6 PTPRH EGFR PTPRO

2.38e-0477794int:NGLY1
InteractionABCC1 interactions

DPP4 SURF1 NTRK1 UNC93B1 STT3B

2.40e-04142795int:ABCC1
InteractionTM9SF3 interactions

ACE2 DPP4 EGFR SLC35E1 UNC93B1

2.48e-04143795int:TM9SF3
InteractionPHB2 interactions

ACE2 DPP4 EGFR SURF1 NTRK1 TAX1BP1 COX6B1 NIPSNAP2 UNC93B1

2.59e-04540799int:PHB2
InteractionCOG1 interactions

EGFR NTRK1 UNC93B1 CHRM4

2.63e-0479794int:COG1
InteractionSEL1L interactions

FBXO6 EGFR PTPRO NTRK1 UNC93B1

2.64e-04145795int:SEL1L
InteractionXPO5 interactions

ACE2 DPP4 PTPRH EGFR NTRK1 UNC93B1

2.68e-04227796int:XPO5
InteractionMMP14 interactions

ACE2 FBXO6 PTPRH PTPRO

2.76e-0480794int:MMP14
InteractionTTC13 interactions

DPP4 FBXO6 EGFR PTPRO

2.76e-0480794int:TTC13
InteractionPTPRF interactions

ACE2 DPP4 FAM171A2 EGFR PTPRO NTRK1

3.08e-04233796int:PTPRF
InteractionABCB7 interactions

EGFR SURF1 NTRK1 TAX1BP1 UNC93B1

3.09e-04150795int:ABCB7
InteractionADCYAP1R1 interactions

ZDHHC15 ADCYAP1R1

3.15e-047792int:ADCYAP1R1
InteractionAUP1 interactions

FBXO6 EGFR PTPRO NTRK1 UNC93B1 STT3B

3.15e-04234796int:AUP1
InteractionCLGN interactions

DPP4 MBTPS1 HLA-DMB PTPRO NTRK1 UNC93B1

3.22e-04235796int:CLGN
InteractionERLIN2 interactions

ACE2 DPP4 FBXO6 NTRK1 TAX1BP1 UNC93B1

3.30e-04236796int:ERLIN2
InteractionLMAN1 interactions

DPP4 PTPRH PTPRO SLC19A1 NTRK1 MACO1 IFIT2 STT3B

3.31e-04441798int:LMAN1
InteractionPTPRH interactions

DOK1 PTPRH EGFR PTPRO

3.33e-0484794int:PTPRH
InteractionUNC5C interactions

ACE2 DPP4 NTRK1

3.77e-0436793int:UNC5C
InteractionGGH interactions

MBTPS1 FBXO6 EGFR NTRK1 MKLN1 UNC93B1

3.85e-04243796int:GGH
InteractionVDAC3 interactions

ACE2 DPP4 FBXO6 MRC2 NTRK1 UNC93B1 PQBP1

3.95e-04343797int:VDAC3
InteractionGJD3 interactions

EGFR SLC19A1 SCD MACO1 KIAA0319L SLC35E1 APBB1 STT3B

4.02e-04454798int:GJD3
InteractionSPTLC1 interactions

FBXO6 EGFR NTRK1 UNC93B1 STT3B

4.04e-04159795int:SPTLC1
InteractionIPO11 interactions

FBXO6 EGFR NTRK1 UNC93B1 CHRM4

4.04e-04159795int:IPO11
InteractionATP1A1 interactions

ACE2 DPP4 SLC8A1 FBXO6 EGFR SCD NTRK1 NIPSNAP2 UNC93B1

4.10e-04575799int:ATP1A1
InteractionTM2D1 interactions

PCNX3 EGFR

4.18e-048792int:TM2D1
InteractionABCA4 interactions

ABCA4 ABCA13

4.18e-048792int:ABCA4
InteractionTEC interactions

DOK1 EGFR NTRK1 IGSF9B

4.33e-0490794int:TEC
InteractionSLC1A5 interactions

ACE2 DPP4 FBXO6 EGFR NTRK1 UNC93B1

4.67e-04252796int:SLC1A5
InteractionBRAT1 interactions

NTRK1 TAX1BP1 NCBP1 CHRM4

5.10e-0494794int:BRAT1
InteractionCAND2 interactions

PTPRH EGFR UNC93B1 CHRM4

5.31e-0495794int:CAND2
InteractionRNMT interactions

ACE2 EGFR NTRK1 NCBP1

5.31e-0495794int:RNMT
InteractionMARCKS interactions

ACE2 FAM171A2 EGFR SLC19A1 NTRK1 MACO1 TAX1BP1 KIAA0319L STT3B

5.64e-04601799int:MARCKS
InteractionLONP1 interactions

ACE2 DPP4 EGFR NTRK1 MKLN1 NIPSNAP2 IFIT5 IFIT3

5.72e-04479798int:LONP1
InteractionDPM1 interactions

ACE2 FBXO6 EGFR NTRK1 UNC93B1

5.94e-04173795int:DPM1
InteractionGNAS interactions

ACE2 DPP4 EGFR NTRK1 TAX1BP1 ADCY5

5.97e-04264796int:GNAS
InteractionGORASP2 interactions

ACE2 DPP4 EGFR NTRK1 SLC35E1 IFIT5 ZER1

6.10e-04369797int:GORASP2
Cytoband7p12

EGFR NIPSNAP2

3.15e-0628227p12
Cytoband2q24.3

DPP4 G6PC2

3.72e-04168222q24.3
Cytoband10q23.31

IFIT5 IFIT2

1.70e-033482210q23.31
GeneFamilyGlucose 6-phosphatases, catalytic

G6PC2 G6PC1

2.24e-0535021074
GeneFamilyCholinergic receptors muscarinic

CHRM2 CHRM4

7.46e-055502180
GeneFamilyApolipoprotein B mRNA editing enzyme catalytic subunits

APOBEC3D APOBEC3C

4.86e-0412502406
GeneFamilyATP binding cassette subfamily A

ABCA4 ABCA13

6.68e-0414502805
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRH PTPRO

1.52e-0321502813
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

IFIT5 IFIT2 IFIT3

3.95e-03115503769
GeneFamilySolute carriers

SLC6A18 SLC8A2 SLC8A1 SLC19A1 SLC35E1

4.59e-03395505752
GeneFamilyX-linked mental retardation|Angiotensin receptors

ZDHHC15 PQBP1

9.44e-0353502103
GeneFamilyFibronectin type III domain containing

PTPRH PTPRO IGSF9B

9.83e-03160503555
GeneFamilyImmunoglobulin heavy locus at 14q32.33

IGHV5-51 IGHV4-38-2 IGHV4-59

1.49e-02187503349
CoexpressionERWIN_COHEN_BLOOD_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_2DY_UP

FBXO6 KIAA0319L HELZ2 IFIT5 IFIT2 IFIT3

1.90e-06119816M41139
CoexpressionBLANCO_MELO_COVID19_SARS_COV_2_LOW_MOI_INFECTION_A594_ACE2_EXPRESSING_CELLS_DN

DPP4 PSG5 ADCY5

1.01e-0514813M34015
CoexpressionFULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN

SLC8A1 HLA-DMB SLC35E1 IFIT5 FUCA1 APOBEC3C UNC93B1 IFIT2 IFIT3

1.20e-05458819M4785
CoexpressionZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_UP

DOK1 MFSD2A SLC8A1 FBXO6 HLA-DMB PTPRO KIAA0319L HELZ2 IFIT5 UNC93B1 IFIT2 LYST IFIT3

1.29e-0510128113M40868
CoexpressionBLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_DEL_NS1_INFECTION_UP

MFSD14A ACE2 DPP4 SLC8A2 FBXO6 HELZ2 IFIT5 UNC93B1 IFIT2 IFIT3

2.93e-056448110M34026
CoexpressionGSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_DN

CELA2A HELZ2 IFIT5 UNC93B1 IFIT2 IFIT3

3.21e-05195816M4292
CoexpressionGAUCHER_PBMC_YF_VAX_STAMARIL_UNKNOWN_AGE_7DY_UP

FBXO6 KIAA0319L HELZ2 IFIT5 UNC93B1 IFIT2 IFIT3

3.41e-05292817M41140
CoexpressionGSE27786_NKCELL_VS_ERYTHROBLAST_UP

MFSD14A FBXO6 ICMT SURF1 KIAA0319L UNC93B1

3.69e-05200816M4853
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

MFSD14A PCNX3 HLA-DMB ICMT SLC19A1 MRC2 SCD HELZ2 CTNS ALG12

4.68e-056818110M5314
CoexpressionFRANCO_BLOOD_SANOFI_PASTEUR_SA_INACTIVATED_INFLUENZA_VACCINE_CORRELATED_WITH_ANTIBODY_RESPONSE_AGE_18_40YO_1DY_POSITIVE

FBXO6 PTPRO HELZ2 UNC93B1 IFIT3

5.07e-05129815M41110
CoexpressionBEIER_GLIOMA_STEM_CELL_DN

FBXO6 HLA-DMB IFIT5 FUCA1

5.59e-0567814M11720
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

MFSD14A PCNX3 HLA-DMB ICMT SLC19A1 MRC2 SCD HELZ2 CTNS ALG12

6.11e-057038110MM1055
CoexpressionGAUCHER_PBMC_YF_VAX_STAMARIL_UNKNOWN_AGE_3DY_UP

FBXO6 KIAA0319L HELZ2 IFIT5 IFIT2 IFIT3

6.12e-05219816M41142
CoexpressionTRAVAGLINI_LUNG_SIGNALING_ALVEOLAR_EPITHELIAL_TYPE_2_CELL

DUOX1 ATP8A1 SCD PGC

7.02e-0571814M41661
CoexpressionERWIN_COHEN_BLOOD_VACCINE_TC_83_AGE_23_48YO_VACCINATED_VS_CONTROL_7DY_UP

FBXO6 IFIT5 IFIT2 IFIT3

7.42e-0572814M41023
CoexpressionMOSERLE_IFNA_RESPONSE

IFIT5 IFIT2 IFIT3

1.20e-0431813M3218
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_top-relative-expression-ranked_1000

SLC6A18 ATPSCKMT EPHX2 ACE2 MFSD2A SLC19A1 SURF1 TAX1BP1 RBPMS2 PTGR2 FUCA1 G6PC1 IFIT3

2.92e-058878113gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_1000
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_500

SLC6A18 EPHX2 ACE2 DPP4 MFSD2A ABCA13 SCD G6PC1 IFIT3

3.40e-05424819gudmap_kidney_adult_RenalCortexMixed_Std_500
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

SLC6A18 EPHX2 ACE2 DPP4 SLC8A1 ABCA13 TMEM254 JPH2 PTGR2 FUCA1 G6PC1 IFIT3

4.83e-057998112gudmap_kidney_adult_JuxtaGlom_Ren1_1000
CoexpressionAtlaskidney single cell_adult_RenalCortexMixed_StemCellamp_k-means-cluster#1_top-relative-expression-ranked_1000

SLC6A18 ATPSCKMT EPHX2 ACE2 MFSD2A SLC19A1 SURF1 RBPMS2 PTGR2 FUCA1 G6PC1 IFIT3

7.04e-058318112gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_k1_1000
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_1000

SLC6A18 EPHX2 ACE2 DPP4 MFSD2A ABCA13 SCD TMEM254 PTGR2 FUCA1 G6PC1 IFIT3

9.86e-058618112gudmap_kidney_adult_RenalCortexMixed_Std_1000
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

DPP4 MFSD2A DUOX1 EGFR SCD PGC

1.08e-06184816369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellCOVID-19-lung-AT2|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.31e-0619081627a1a86620fe9b5ee930d388b32352206485e6d0
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.35e-06191816276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellMild/Remission-B_activate-7|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FBXO6 HELZ2 IFIT5 UNC93B1 IFIT2 IFIT3

1.35e-06191816382686d62f7b8576c44bb9726a4e10dc26fd348e
ToppCellMild/Remission-B_activate-7|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

FBXO6 HELZ2 IFIT5 UNC93B1 IFIT2 IFIT3

1.48e-0619481601c97543972159a9468272da06e7e611e2c21fae
ToppCellCV-Moderate-1|Moderate / Virus stimulation, Condition and Cluster

FBXO6 HELZ2 IFIT5 IFIT2 LYST IFIT3

1.57e-06196816b50cfcd87c5b67806450cb8b3c6860ab97f6d3b1
ToppCellASK440-Epithelial-Type_2|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.57e-06196816754b4202b617165c6994a0b5a9b1e486dccdd44d
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.57e-0619681665e161fd672e37a5d10f28011bb422c4d7042d6a
ToppCellCD8+_Memory_T_cell-CV-1|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

FBXO6 HELZ2 IFIT5 IFIT2 LYST IFIT3

1.61e-06197816e59b47bccc781b2117196fe322efa87559c237c6
ToppCellASK440-Epithelial-Type_2|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.61e-0619781608d5bbeb77a4152af1c783bc958afcae24667767
ToppCellCV-Severe-1|CV / Virus stimulation, Condition and Cluster

FBXO6 SCD HELZ2 IFIT5 LYST IFIT3

1.66e-06198816fc0e885e370ffb780eada62bb2b52065c2f8b26b
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.71e-061998162dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.76e-06200816cf1991853e10c562edae9a0d71a209f35b07db80
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.76e-06200816acc771a902cf2f060c3eb9aedb72a256f5778a6c
ToppCellParenchyma_COVID-19-Epithelial-TX-AT2-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.76e-06200816ceb613ac6cdf0e3e6bb3f04d89034e18a524cefb
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.76e-062008167618ae284625c5c121bcc00eb9f07e5b1e3adf23
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.76e-06200816eb44d1f80ecaac3a022cd04ab16dc36151e45488
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-AT2-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DPP4 MFSD2A DUOX1 ATP8A1 SCD PGC

1.76e-0620081623b319bf7e5ae03e5baa777c951da9bfc97cca8c
ToppCellPBMC-Control-cDC_1|Control / Compartment, Disease Groups and Clusters

TMEM232 HELZ2 IFIT5 IFIT2 IFIT3

9.74e-061568159b6c5bcac516a62bcc1f5be32ffa8c92735ef0bc
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

PCNX3 NCBP1 CTNS IFIT2 IFIT3

1.35e-05167815820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 HLA-DMB PTPRO SCD UNC93B1

1.56e-05172815356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 HLA-DMB PTPRO SCD UNC93B1

1.56e-0517281546fadeee483fdf8402df92ec98575a09c6c15b16
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 HLA-DMB PTPRO SCD UNC93B1

1.56e-05172815438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MFSD14A IFIT5 UNC93B1 IFIT2 IFIT3

1.70e-0517581597616bb5c127284aa9e67bc336dfcf29e137164b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB SCD CELA2A UNC93B1 G6PC2

1.70e-0517581582482f3fc716701bed46dc65c2044577aed15427
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB SCD CELA2A UNC93B1 G6PC2

1.70e-051758155092c5159f697e20bf8aa450c414ffd997738d25
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB SCD CELA2A G6PC2 SORCS1

1.70e-05175815887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB SCD CELA2A UNC93B1 PGC

1.74e-05176815077f3fe5e3482ea3f639d789bd3d584161b36c02
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DMB SCD CELA2A UNC93B1 PGC

1.74e-05176815fc2ba468677b19b55130c1f06737f40300cd9d2e
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A2 SLC8A1 RBPMS2 JPH2 ADCY5

1.89e-051798158da6863edc756540bb097cc7221c1408640d9bb4
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A2 SLC8A1 RBPMS2 JPH2 ADCY5

1.89e-05179815f39c13c99a07d009cc677e363ffe089089c64916
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PTPRO HELZ2 IFIT5 IFIT2 IFIT3

2.10e-05183815dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

HLA-DMB PTPRO SCD IFIT2 IFIT3

2.27e-05186815ddfadd43efeac3b3e6b7062590cc2b8f2f2db2ab
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD2A DUOX1 ATP8A1 SCD PGC

2.33e-051878157c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPP4 MFSD2A DUOX1 ATP8A1 PGC

2.33e-051878155df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 FAM171A2 EGFR ABCA13 MRC2

2.33e-051878159225caf66e06ebe57e90d677122acb6498607f36
ToppCellIPF-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

DPP4 MFSD2A ATP8A1 SCD PGC

2.39e-051888155f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 RBPMS2 JPH2 IGSF9B ADCY5

2.45e-05189815127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD2A DUOX1 MRC2 SCD PGC

2.45e-05189815da014519d6eb21bc2dc2ed65eafe638b42a068ed
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 RBPMS2 JPH2 IGSF9B ADCY5

2.45e-051898152cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

HELZ2 IFIT5 UNC93B1 IFIT2 IFIT3

2.58e-051918152da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellwk_20-22-Hematologic-Myeloid-APOE+_Mac1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FBXO6 SCD SURF1 FUCA1 CTNS

2.58e-05191815c204ec71b7755b46a18d3a6aa84d0f407145ce9d
ToppCellCV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

FBXO6 HELZ2 IFIT5 IFIT2 IFIT3

2.65e-051928152a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPP4 DUOX1 ATP8A1 KIAA0319L PGC

2.65e-0519281529f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 SLC8A2 RBPMS2 JPH2 ADCY5

2.71e-051938151043b28503bfaa0d5a82ec358bc86cbde73ea8f2
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP4 MFSD2A DUOX1 SCD PGC

2.71e-051938158646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 FAM171A2 EGFR ABCA13 MRC2

2.71e-051938150f2167eef8203a5659c8c72e4e77646003d64797
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 SLC8A2 RBPMS2 JPH2 ADCY5

2.71e-051938150266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MFSD2A DUOX1 ATP8A1 EGFR PGC

2.78e-0519481553f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SLC8A1 HELZ2 IFIT5 IFIT2 IFIT3

2.78e-05194815e36d1fd141bdcbd9ed66a33de6cdfde77189a0c1
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MFSD2A DUOX1 ATP8A1 SCD PGC

2.85e-051958156867f9c56ea27a17c8c4099aae0d79903c3748a5
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD2A DUOX1 ATP8A1 SCD PGC

2.85e-05195815d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCellCOVID-19_Moderate-CD8+_T_activated|World / disease group, cell group and cell class

FBXO6 HELZ2 IFIT5 IFIT2 IFIT3

2.85e-05195815070c5d3bdbd4ea54a579c01c37fb99bcf823982e
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MFSD2A DUOX1 ATP8A1 SCD PGC

2.85e-05195815955a0a7244cd7eaf006a39e1bd03333baf6f30a4
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

PTPRO SCD FUCA1 IFIT2 IFIT3

2.85e-051958156800c17026ec6c56132bf4664b8fcd74d7836579
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD2A DUOX1 ATP8A1 MRC2 PGC

2.92e-051968157e5addaa844e66f8160e05858c341866a80aed23
ToppCellmild-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

KIAA0319L HELZ2 IFIT5 IFIT2 IFIT3

2.92e-05196815ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCellcellseq-Epithelial-Epithelial_Alveolar|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MFSD2A DUOX1 ATP8A1 SCD PGC

2.92e-05196815a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

FBXO6 HELZ2 IFIT5 IFIT2 IFIT3

2.92e-0519681579632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFSD2A DUOX1 ATP8A1 SCD PGC

2.92e-0519681583aeb96a33802949238d8a097086a1812201d1b5
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

HELZ2 IFIT5 UNC93B1 IFIT2 IFIT3

2.92e-05196815417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellCV-Moderate-1|CV / Virus stimulation, Condition and Cluster

FBXO6 HELZ2 IFIT5 IFIT2 IFIT3

2.99e-05197815e3d00d850b4d191f9592ef993c0eaadfe5710b5f
ToppCellCV-Severe-1|Severe / Virus stimulation, Condition and Cluster

FBXO6 HELZ2 IFIT5 IFIT2 IFIT3

3.07e-051988159b9ee0b0f6cc92e7be94869604c98f43d57ff8ff
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DPP4 MFSD2A ATP8A1 SCD PGC

3.07e-0519881585215015bb86ada0e871c413a4ecdc903a3785ca
ToppCellAT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

MFSD2A DUOX1 EGFR SCD PGC

3.07e-05198815893036558a9ad86b57f9e735df35812e9d18739e
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

FBXO6 HELZ2 IFIT2 LYST IFIT3

3.07e-05198815ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCellASK428-Epithelial-Type_2|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

MFSD2A DUOX1 ATP8A1 SCD PGC

3.07e-05198815ec0d1801363adb70c6a26655b79d12b438c7417d
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC8A1 JPH2 IGSF9B CHRM2 ADCY5

3.07e-05198815c12e7511628db819a52959bb68580e27c00c2e41
ToppCellCV-Mild-1|CV / Virus stimulation, Condition and Cluster

FBXO6 HELZ2 IFIT5 IFIT2 IFIT3

3.07e-051988154b078714c49e7befb7b113d72485e712236d35fa
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHX2 ACE2 DPP4 PTPRH G6PC1

3.07e-05198815c48b3f026b16d48b8eca9f74dc1e3f3f39a89322
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC8A1 JPH2 IGSF9B CHRM2 ADCY5

3.07e-0519881522e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DPP4 MFSD2A ATP8A1 SCD PGC

3.07e-0519881538349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

MRC2 HELZ2 IGHV4-59 IFIT2 IFIT3

3.07e-05198815ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

DPP4 MFSD2A DUOX1 SCD PGC

3.14e-051998159a65acfe9bf500db72142469cf17bf0973540001
ToppCellBAL-Severe-cDC_1|Severe / Compartment, Disease Groups and Clusters

SLC8A1 HELZ2 UNC93B1 IFIT2 IFIT3

3.14e-051998159f5750212b887f92761ade33fc6e108cd5275297
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

HLA-DMB HELZ2 UNC93B1 IFIT2 IFIT3

3.14e-05199815933201d32eda12a89660bdbae9114a95cc428a38
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

SLC8A1 HELZ2 UNC93B1 IFIT2 IFIT3

3.14e-05199815c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellBiopsy_IPF-Epithelial-AT2|Biopsy_IPF / Sample group, Lineage and Cell type

DPP4 MFSD2A DUOX1 SCD PGC

3.14e-05199815c841d475703d3489161fb7904526bd7563d5fb0f
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

MFSD2A DUOX1 ATP8A1 SCD PGC

3.14e-05199815e28ace2ca680c6154398e17110aa1838dd7a5548
ToppCellproximal-Epithelial-Signaling_Alveolar_Epithelial_Type_2-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MFSD2A DUOX1 ATP8A1 SCD PGC

3.22e-052008157bd76884fcffdbd9b8d24f5b6b5187ad3963da5f
ToppCellSepsis-Leuk-UTI|Sepsis / Disease, condition lineage and cell class

ZDHHC15 CFAP251 HLA-DMB IFIT2 IFIT3

3.22e-052008157d92b24c0c888dd46e40b7e3c6c2645c3604f132
ToppCellproximal-Epithelial-Signaling_Alveolar_Epithelial_Type_2|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MFSD2A DUOX1 ATP8A1 SCD PGC

3.22e-05200815af57f837eb7f988d24fc4612d16d68121498f0b0
ToppCellproximal-3-Epithelial-Signaling_Alveolar_Epithelial_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MFSD2A DUOX1 ATP8A1 SCD PGC

3.22e-052008159c7859659843b1566bdf623b269b5e166c89d38c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPHX2 STK32B IFIT2 IFIT3

6.61e-05119814e868453c02dcf0e07821886b81ca739887d43c67
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPRO IFIT5 IFIT2 IFIT3

9.05e-05129814e50bd63ad8035abf5135d7d2cb8636206d6e69a5
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPHX2 STK32B IFIT2 IFIT3

9.05e-05129814f83187c0bb06528127b8d2d56674ab1946846951
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PTPRH TAX1BP1 STK32B CTNS

9.60e-051318142ccf679b5035b7b9cdb9a9a660cad90288592187
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 ABCA4 G6PC1 SORCS1

1.28e-041418144aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 ABCA4 G6PC1 SORCS1

1.28e-04141814e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PSG5 IFIT5 IFIT2 IFIT3

1.28e-04141814b5e85f89b930a0ec70cc95733c5ab76ac3e9497f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPHX2 STK32B IFIT2 IFIT3

1.35e-0414381424fd24846fbef049af669a57d42fcc18928d2b27
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHX2 EGFR SCD G6PC1

1.50e-0414781400619115b9a1ec2b967c2992043b41974ece63c4
ToppCellLymphoid-Lymphoid-B_cells|Lymphoid / shred on cell class and cell subclass (v4)

HLA-DMB SCD MACO1 UNC93B1

1.62e-041508145ebf6b4b9b029422a4676ba09a6a9225bd25db47
ToppCellFrontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACE2 SLC19A1 RBPMS2 JPH2

1.66e-04151814527059e47e381b2f6d63c1abb39bc0795ee3829d
ToppCellFrontal_cortex-Endothelial-MURAL|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ACE2 SLC19A1 RBPMS2 JPH2

1.66e-041518147570372a315bc312ff57bb5f483375c401ae8787
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

MFSD14A PCNX1 IFIT2 IFIT3

1.70e-041528142ff0980dfd8d430cca14649151d856edef115720
ToppCellMS-CD4-antiviral_CD4|MS / Condition, Cell_class and T cell subcluster

HELZ2 IFIT5 IFIT2 IFIT3

1.70e-04152814b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCellNS-critical-d_16-33-Myeloid-Monocyte-derived_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HELZ2 IFIT5 IFIT2 IFIT3

1.75e-04153814859de35b24c5d7d73be1c213b90b43362ee2e0eb
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOK1 SLC8A1 IFIT5 ALG12

1.79e-0415481416fdafb5c64d2db321554f87129a962d113f1668
ToppCelllymphoid-T_cell-pro-T_cell|T_cell / Lineage, cell class and subclass

PCNX3 IFIT2 IFIT3 SORCS1

2.07e-0416081466fe86d2f37983761141e5bb3de127f0b4bb0951
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

MFSD2A DUOX1 SCD PGC

1.03e-0450534GAVISH_3CA_MALIGNANT_METAPROGRAM_31_ALVEOLAR
DrugMebeverine hydrochloride [2753-45-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A

DOK1 EPHX2 EGFR MRC2 KIAA0319L NCBP1 APOBEC3C

5.97e-061997976795_UP
Drugphlorobenzophenone

ICMT LYST

1.19e-052792CID000077093
Drughimbacine

CHRM2 CHRM4

1.19e-052792ctd:C048172
Drug14,15-eicosa-5-enoic acid

EPHX2 EGFR

1.19e-052792ctd:C494022
Drugepicholesterol

EPHX2 MBTPS1 ABCA4 EGFR SCD TAX1BP1 G6PC2 CHRM2 LYST G6PC1 ADCY5

1.20e-056367911CID000000304
DrugNSC236997

ACE2 DPP4 DUOX1 EGFR PTPRO SCD NTRK1 LYST G6PC1 ADCY5

1.69e-055397910CID000005300
DrugH S Q

MBTPS1 SPAM1 MRC2 ALG8 FUCA1 IFIT3 ALG12 STT3B

2.97e-05351798CID000000897
DrugAmitriptyline

NTRK1 CHRM2 CHRM4

3.16e-0518793DB00321
DrugUNC 0638

IFIT2 CHRM2 IFIT3

3.16e-0518793ctd:C561310
DrugCinnamylbenzene

EPHX2 ICMT

3.56e-053792CID000099034
Drugeburnamonine

CHRM2 CHRM4

3.56e-053792ctd:C016422
DrugBepridil hydrochloride [74764-40-2]; Up 200; 10uM; MCF7; HT_HG-U133A

DUOX1 SLC8A1 EGFR PCNX1 IFIT2 IFIT3

5.23e-051907965674_UP
DrugTiclopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; MCF7; HT_HG-U133A

DOK1 NTRK1 APOBEC3C IFIT2 CHRM4 IFIT3

5.23e-051907964155_UP
DrugTiapride hydrochloride [51012-33-0]; Down 200; 11uM; PC3; HT_HG-U133A

MBTPS1 SLC19A1 MACO1 APBB1 CTNS IFIT2

6.04e-051957963663_DN
DrugLY294002; Up 200; 10uM; PC3; HG-U133A

DPP4 MBTPS1 SLC8A1 SPAM1 ZER1 CHRM4

6.04e-05195796429_UP
DrugPenbutolol sulfate [38363-32-5]; Down 200; 5.8uM; MCF7; HT_HG-U133A

SLC19A1 KIAA0319L SLC35E1 PCNX1 LYST ALG12

6.22e-051967963534_DN
DrugTrimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A

DOK1 TAX1BP1 ZER1 PCNX1 LYST ALG12

6.22e-051967963342_DN
Drugtetraethylenepentamine pentahydrochloride; Up 200; 100uM; ssMCF7; HG-U133A

ACE2 MRC2 MACO1 PCNX1 IFIT2 CARD8

6.40e-05197796498_UP
DrugFursultiamine Hydrochloride [2105-43-3]; Down 200; 9.2uM; PC3; HT_HG-U133A

EGFR MRC2 ZER1 PCNX1 CTNS ALG12

6.58e-051987966630_DN
DrugCarteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; HL60; HT_HG-U133A

DOK1 PTPRO SLC19A1 TMEM254 APOBEC3C LYST

6.58e-051987961340_DN
DrugZardaverine [101975-10-4]; Down 200; 15uM; PC3; HT_HG-U133A

DPP4 PTPRH ZER1 RS1 IFIT2 ALG12

6.76e-051997964209_DN
Drugfurtrethonium

CHRM2 CHRM4

7.10e-054792ctd:C028530
DrugHyoscyamine

CHRM2 CHRM4

7.10e-054792DB00424
DrugProcyclidine

CHRM2 CHRM4

7.10e-054792DB00387
DrugTropicamide

CHRM2 CHRM4

7.10e-054792DB00809
Drug5-methylfurtrethonium

CHRM2 CHRM4

7.10e-054792ctd:C008446
Drugquingestanol acetate

APOBEC3C G6PC1

7.10e-054792CID000018142
Drug5-nitrosalicylaldehyde

DPP4 G6PC2 G6PC1

8.75e-0525793CID000066808
DrugAtropine

CHRM2 CHRM4

1.18e-045792DB00572
DrugDarifenacin

CHRM2 CHRM4

1.18e-045792DB00496
DrugMetixene

CHRM2 CHRM4

1.18e-045792DB00340
DrugTrihexyphenidyl

CHRM2 CHRM4

1.18e-045792DB00376
DrugSolifenacin

CHRM2 CHRM4

1.18e-045792DB01591
Drug5-(3-(3-hydroxyphenoxy)azetidin-1-yl)-5-methyl-2,2-diphenylhexanamide

CHRM2 CHRM4

1.18e-045792ctd:C568516
Drugxanomeline

CHRM2 CHRM4

1.18e-045792ctd:C075257
DrugPipecuronium

CHRM2 CHRM4

1.18e-045792ctd:D017300
DrugN-Methylscopolamine

CHRM2 CHRM4

1.18e-045792ctd:D019832
DrugCryptenamine

CHRM2 CHRM4

1.18e-045792DB00785
DrugHomatropine Methylbromide

CHRM2 CHRM4

1.18e-045792DB00725
DrugFesoterodine

CHRM2 CHRM4

1.18e-045792DB06702
DrugScopolamine Derivatives

CHRM2 CHRM4

1.18e-045792ctd:D012602
DrugTolterodine

CHRM2 CHRM4

1.18e-045792DB01036
DrugQuinuclidinyl Benzilate

CHRM2 CHRM4

1.18e-045792ctd:D011813
DrugGallamine Triethiodide

CHRM2 CHRM4

1.77e-046792ctd:D005703
Drugacetone hydrazone

ACE2 EGFR

1.77e-046792CID000078937
DrugAC1Q5R6K

ACE2 PGC

1.77e-046792CID000114973
DrugBrompheniramine

CHRM2 CHRM4

1.77e-046792DB00835
DrugBenzquinamide

CHRM2 CHRM4

1.77e-046792DB00767
DrugScopolamine

CHRM2 CHRM4

1.77e-046792DB00747
DrugCrotalid Venoms

CHRM2 CHRM4

1.77e-046792ctd:D003435
Drug2-mercaptonicotinic acid

G6PC2 G6PC1

1.77e-046792CID000673681
Drugbrucine N-oxide

CHRM2 CHRM4

1.77e-046792ctd:C083067
DiseasePR interval

MFSD2A SLC8A1 PCNX3 RBPMS2 MKLN1 CHRM2 ADCY5

2.89e-04495767EFO_0004462
DiseaseInfluenza

IFIT5 IFIT2 IFIT3

3.31e-0452763C0021400
DiseaseAnimal Mammary Neoplasms

EGFR MRC2 SCD ADCY5

5.04e-04142764C0024667
DiseaseMammary Carcinoma, Animal

EGFR MRC2 SCD ADCY5

5.04e-04142764C1257925
Diseasecongenital disorder of glycosylation type I (implicated_via_orthology)

ALG8 ALG12

6.73e-0415762DOID:0050570 (implicated_via_orthology)
DiseaseMammary Neoplasms, Experimental

EGFR MRC2 SCD ADCY5

7.00e-04155764C0024668
DiseaseCarcinomatosis

EGFR MRC2 SCD ADCY5

8.45e-04163764C0205699
DiseaseCarcinoma, Spindle-Cell

EGFR MRC2 SCD ADCY5

8.45e-04163764C0205697
DiseaseUndifferentiated carcinoma

EGFR MRC2 SCD ADCY5

8.45e-04163764C0205698
DiseaseAnaplastic carcinoma

EGFR MRC2 SCD ADCY5

8.45e-04163764C0205696
DiseaseCarcinoma

EGFR MRC2 SCD ADCY5

8.65e-04164764C0007097
Diseaseglaucoma (implicated_via_orthology)

ACE2 NTRK1

8.68e-0417762DOID:1686 (implicated_via_orthology)
DiseaseIntellectual Disability

ACE2 MFSD2A SURF1 FUCA1 PQBP1 STT3B

1.04e-03447766C3714756
Diseasecytochrome-c oxidase deficiency disease (is_implicated_in)

SURF1 COX6B1

1.09e-0319762DOID:3762 (is_implicated_in)
DiseaseHypertensive disease

SLC6A18 ACE2 CELA2A ADCY5

1.49e-03190764C0020538
DiseaseBMI-adjusted fasting blood glucose measurement

G6PC2 ADCY5

1.60e-0323762EFO_0008036
DiseaseCytochrome-c Oxidase Deficiency

SURF1 COX6B1

1.74e-0324762C0268237
DiseaseFEV change measurement, response to zileuton

EPHX2 PCNX1

1.89e-0325762EFO_0005921, EFO_0007676

Protein segments in the cluster

PeptideGeneStartEntry
PDTVWSIGYWLCYVN

CHRM4

431

P08173
LSPNTNYEVTWYTSW

APOBEC3D

276

Q96AK3
SGVSPTTYWVTNFLW

ABCA4

1716

P78363
SPNTKYQVTWYTSWS

APOBEC3C

81

Q9NRW3
PWYFPFTASYWKSVG

ABCA13

3786

Q86UQ4
VWTIGYWLCYINSTI

CHRM2

421

P08172
SGTYYWHIPTGTTQW

APBB1

266

O00213
PWQVSLQYSSNGKWY

CELA2A

41

P08217
SEGIWWTVFFIYTIY

ADCY5

326

O95622
YWAGWYGPRVTNSSI

FBXO6

241

Q9NRD1
ALWVVFFGIYSSLWP

ATP8A1

1016

Q9Y2Q0
KSSNWGTSPLLWYFY

ALG12

251

Q9BV10
MTWSFGWNSSLPVYY

CFAP251

251

Q8TBY9
TSYPVSWSSVIGVWY

CRISP1

106

P54107
RWYPSSDTTQQGWKY

RBPMS2

191

Q6ZRY4
YPCTLVGTWNTWYGE

NIPSNAP2

106

O75323
KYYWWFFQTVPGLTG

DUOX1

1181

Q9NRD9
VLWEIFTYGKQPWYQ

NTRK1

716

P04629
VYTWPSGNTFEGYWS

JPH2

51

Q9BR39
RDWYVYAFLSSLPWV

NCBP1

166

Q09161
YSSVLWPWSGYLAIS

MBTPS1

551

Q14703
PASWILSGYYWQTSA

KIAA0319L

11

Q8IZA0
PIQWLFFAASTYVWV

MACO1

96

Q8N5G2
FVYTYIAPWQITWGS

PCNX1

1456

Q96RV3
LTYIAPWQITWGSAF

PCNX3

1246

Q9H6A9
PDTYWNSTNFLSWLY

FUCA1

236

P04066
YSWVSEEPLNYVGWQ

MRC2

1196

Q9UBG0
YSALWWSPNGTFLAY

DPP4

211

P27487
HLSSDGTYFYWIWSP

HECTD4

16

Q9Y4D8
GTYFYWIWSPASLNE

HECTD4

21

Q9Y4D8
GSISSYYWSWIRQPP

IGHV4-59

46

P01825
YSISSGYYWGWIRQP

IGHV4-38-2

46

P0DP08
ISPWWYFAVISVSGV

MFSD14A

121

Q96MC6
FYWYTIIGWGTPTVC

ADCYAP1R1

266

P41586
YSFTSYWIGWVRQMP

IGHV5-51

46

A0A0C4DH38
LWTDYLLAFYINPWS

PTPRO

891

Q16827
QLYWTFVSPQLGYWV

FAM171A2

276

A8MVW0
IWFVPDFPHGQTYWY

MFSD2A

146

Q8NA29
GLPYYWNADTDLVSW

PQBP1

61

O60828
YTHQSDVWSYGVTVW

EGFR

891

P00533
YVWGFYPAEVTITWR

HLA-DMB

136

P28068
PSYVGWFYWSIGTQV

ICMT

211

O60725
GFPESWYSWRYQIPA

EPHX2

266

P34913
VRSLVTWGNYAWVYY

IFIT5

91

Q13325
YSPTWEGSQFWVTVQ

DOK1

146

Q99704
GQRPYWWVLDTDYYS

G6PC1

81

P35575
WWVLDTDYYSNTSVP

G6PC1

86

P35575
IRSLVTWGNYAWVYY

IFIT3

91

O14879
STNRYSVWFPTAGWY

CARD8

176

Q9Y2G2
WGRFWTNLYSLTVPF

ACE2

271

Q9BYF1
FGHRPYWWVQETQIY

G6PC2

76

Q9NQR9
VWYDPIYYPTSWQLD

LYST

2936

Q99698
IRSLVTWGNYAWVYY

IFIT2

91

P09913
WLWNESTALYPSIYL

SPAM1

251

P38567
GWIYFVAWSISFYPQ

CTNS

131

O60931
YSLQVDWYTWATSPI

HELZ2

1661

Q9BYK8
WYQRVYQSLCPTSWV

COX6B1

56

P14854
GWSTARDYYTFLWSP

TAX1BP1

56

Q86VP1
LLSWGPSFNFSIWYV

MKLN1

136

Q9UL63
VTWYGLSAATSYLWF

SURF1

276

Q15526
FLVSSDLTYVYQWPW

SLC35E1

246

Q96K37
ISLYYNTIVAWVLWY

SLC6A18

111

Q96N87
FTAVGYELNPWLVWY

ATPSCKMT

111

Q6P4H8
PISQWYYEATSEWTL

ALG8

51

Q9BVK2
VLDPSGDYYYWWLNT

CNGA4

26

Q8IV77
QLGPTEASYYWVYWV

UBFD1

276

O14562
WATWALYNLVSVYPD

ZER1

701

Q7Z7L7
WWQAVAIFTVYLGSS

UNC93B1

476

Q9H1C4
TGQIYWAPVTQELYW

PGC

236

P20142
RAEAYPGNLTYTWYW

IGSF9B

251

Q9UPX0
FSWAWNVVYIYTVIL

TMEM232

351

C9JQI7
YIAPWSGRFYSLWDT

STT3B

376

Q8TCJ2
SLWWVFNSAGYYLVV

SLC19A1

271

P41440
TLVPWYFWGETFQNS

SCD

231

O00767
GYSYPVDWWSLGITA

STK32B

201

Q9NY57
PEQYVGWYSSWTANK

RS1

86

O15537
LTYVWWYGNNTEPLI

SORCS1

921

Q8WY21
ITLSFGYYTWVVFWP

TMEM254

21

Q8TBM7
GYYTWVVFWPQSIPY

TMEM254

26

Q8TBM7
YTYIWWLNGQSLPVS

PSG5

176

Q15238
PGQSSYSYWVSWVRE

PTPRH

501

Q9HD43
TKGDFVTSFYWPWQT

PTGR2

91

Q8N8N7
VFFTWTYWKSIFTLP

ZDHHC15

66

Q96MV8
VTAAWSIFAYTWLYI

SLC8A1

206

P32418
TASWSIFAYVWLYLI

SLC8A2

201

Q9UPR5