Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainCH

ASPM UTRN IQGAP3

5.91e-0565223SM00033
DomainCH

ASPM UTRN IQGAP3

7.38e-0570223PF00307
DomainIQ

ASPM MYO1A IQGAP3

7.70e-0571223PF00612
Domain-

ASPM UTRN IQGAP3

7.70e-05712231.10.418.10
DomainCH

ASPM UTRN IQGAP3

8.36e-0573223PS50021
DomainCH-domain

ASPM UTRN IQGAP3

9.07e-0575223IPR001715
DomainIQ

ASPM MYO1A IQGAP3

1.14e-0481223SM00015
DomainIQ_motif_EF-hand-BS

ASPM MYO1A IQGAP3

1.56e-0490223IPR000048
DomainIQ

ASPM MYO1A IQGAP3

1.72e-0493223PS50096
Domainfn3

FLRT2 EPHA1

1.54e-02162222PF00041
DomainFN3

FLRT2 EPHA1

1.98e-02185222SM00060
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

ASPM MLANA ALDH2 MYO1A

5.08e-0528825438496616
Pubmed

Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

ASPM TSBP1

1.24e-042325224925725
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

SEC63 LEMD3 UTRN MAP4K3

2.19e-0442125436976175
Pubmed

Replication of previous genome-wide association studies of bone mineral density in premenopausal American women.

TSBP1 MAP4K3

4.61e-044425220200978
Pubmed

Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin.

LEMD3 MEN1

5.48e-044825227703004
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SEC63 LEMD3 UTRN IQGAP3 KNOP1 MEN1

5.51e-04149725631527615
Pubmed

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.

LOXL2 MEN1

5.95e-045025237974198
GeneFamilyFibronectin type III domain containing

FLRT2 EPHA1

5.69e-03160132555
CoexpressionGSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_DN

PTPN12 ZSWIM3 MEN1 LAPTM5

3.00e-05190254M5666
CoexpressionGSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP

ASPM PTPN12 LEMD3 IQGAP3

3.32e-05195254M8006
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_DN

RIPOR1 PTPN12 LOXL2 LAPTM5

3.53e-05198254M8859
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 UTRN LAPTM5

2.75e-06177254227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 UTRN LAPTM5

2.75e-0617725466ffa279147961080c104242a08b176e301d80e3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 UTRN LAPTM5

2.75e-061772540cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 UTRN LAPTM5

3.41e-0618725465d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 UTRN LAPTM5

3.41e-061872544c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 UTRN LAPTM5

3.41e-061872545274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(II)|GI_large-bowel / Manually curated celltypes from each tissue

ALDH2 METAP2 LOXL2 LAPTM5

3.64e-06190254fee64bacbb330d04dc1dc63909838f2c605d9f1f
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHRDL1 FLRT2 UTRN LAPTM5

4.03e-06195254fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHRDL1 FLRT2 UTRN LAPTM5

4.03e-0619525483d45ff5e5bc704448431149fffb2e4c1278f279
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Cdc20)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASPM MYO1A IQGAP3

5.29e-05131253f9fb8d74ca720b81fd5910cc975510359a8ef751
ToppCell10x3'2.3-week_12-13-Myeloid_DC-DC-DC2|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ALDH2 C22orf42 MYO1A

6.45e-05140253c3331cb7720f93af8bab35d02c6cbe87dd324d91
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TSBP1 IQGAP3 LAPTM5

1.07e-04166253063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TSBP1 IQGAP3 LAPTM5

1.07e-04166253417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TSBP1 IQGAP3 LAPTM5

1.07e-04166253f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 FLRT2 LOXL2

1.13e-041692538bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 FLRT2 LOXL2

1.13e-04169253bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 FLRT2 LOXL2

1.13e-041692535f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM FLRT2 IQGAP3

1.17e-04171253c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM IQGAP3 LAPTM5

1.17e-0417125355c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CHRDL1 FLRT2 LOXL2

1.19e-04172253d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASPM METAP2 LAPTM5

1.21e-04173253b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM MLANA IQGAP3

1.21e-04173253506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCell10x5'-lymph-node_spleen-Hematopoietic_progenitors|lymph-node_spleen / Manually curated celltypes from each tissue

ASPM CHRDL1 IQGAP3

1.23e-04174253029394e107bf7ad58056d2216070aa2e964fff12
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MLANA FLRT2 LOXL2

1.27e-041762534ed73c73972334f6dc4229920205547823252fa0
ToppCelldroplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ASPM KLHL11 IQGAP3

1.27e-04176253b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM IQGAP3 LOXL2

1.27e-0417625345c6983ab671b0f306e7390320bd84f848e474cc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 LAPTM5

1.29e-04177253c274fbdc141855ff4581d437d4997c64cc193278
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 LAPTM5

1.29e-04177253c8a51e480b978dc0ded85583261f2c892e085be8
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM FLRT2 IQGAP3

1.29e-041772534197cf2b1e743230c821f422836fa5991b155a52
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CHRDL1 FLRT2 LAPTM5

1.29e-04177253f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

CHRDL1 FLRT2 LAPTM5

1.34e-04179253411620201a860716a8773b92f50f7b94ef34a586
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating-Lymphatic_EC_proliferating_L.2.5.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASPM FLRT2 IQGAP3

1.40e-04182253f703963b5d1e8c1f95d78807521048553b0792d8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLRT2 UTRN LAPTM5

1.40e-0418225341b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLRT2 UTRN LAPTM5

1.40e-041822535e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLRT2 UTRN LAPTM5

1.40e-04182253b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_proliferating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ASPM FLRT2 IQGAP3

1.40e-04182253ebd177ad5eac51bf2db0657596618bdf1e5d46e1
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM IQGAP3 LAPTM5

1.43e-04183253ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCellPND10-Immune-Immune_Myeloid-Dendritic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM IQGAP3 LAPTM5

1.43e-04183253e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM IQGAP3 LAPTM5

1.43e-04183253263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLRT2 UTRN

1.43e-041832534d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASPM PTPN12 IQGAP3

1.43e-0418325342dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PTPN12 MAP4K3 LAPTM5

1.43e-04183253278064c9f0582463b83bf156d34e77f60187613b
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 FLRT2 LOXL2

1.47e-041852533cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 FLRT2 LOXL2

1.47e-0418525300258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 FLRT2 LOXL2

1.47e-04185253a94694e226856bc5b168464f52d76004145717a5
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic|lymph-node_spleen / Manually curated celltypes from each tissue

ASPM FLRT2 IQGAP3

1.47e-04185253912d8efdc37820dbb07736221a98af929e5a7c97
ToppCelldroplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ASPM PTPN12 IQGAP3

1.47e-0418525357c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHRDL1 FLRT2 UTRN

1.50e-0418625340070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

ALDH2 METAP2 LOXL2

1.52e-04187253457eb3791a8c5458d81833e0701ac5a9bfdee2bf
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPN12 ALDH2 LAPTM5

1.52e-041872537b24a324335c30c4b37795c43611b297274c804b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM IQGAP3 LAPTM5

1.52e-0418725373931a5ea73799095daff100b5f18853c57c74dc
ToppCell3'_v3-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

ASPM C22orf42 IQGAP3

1.54e-041882530e8ac42c439f30a05e015210e1d5c2dcb9d9d471
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM IQGAP3 LOXL2

1.54e-0418825395d0a796d62ce6d121e2028c378faffc14b35275
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

ALDH2 LOXL2 LAPTM5

1.59e-04190253bfb16efb23add53eebabc8e48f20c96994ec01da
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|B_lymphocytes / Location, Cell class and cell subclass

ALDH2 METAP2 LOXL2

1.59e-04190253c5c80a6b9087821a2e07250fa90bcd3505f103b6
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHRDL1 FLRT2 LOXL2

1.62e-0419125375d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pro_B_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RIPOR1 UTRN LAPTM5

1.62e-04191253054fa0493b00149313c243d39cf39a264044f074
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHRDL1 FLRT2 LOXL2

1.62e-041912534b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

ASPM ALDH2 IQGAP3

1.62e-04191253aa9c0b1b90cdb7a95d4e6332819f82cae0a79ff9
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHRDL1 FLRT2 LAPTM5

1.64e-041922535f4f44f15d3a2846981e68296643a4634930a211
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CHRDL1 FLRT2 ALDH2

1.64e-041922537ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell367C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHRDL1 FLRT2 LAPTM5

1.64e-041922535e709c0714e8eba27e03a6def0544256bedb3ced
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRDL1 FLRT2 LOXL2

1.67e-04193253316ebdf15f75d88c348f909b643fcd315364ca84
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM IQGAP3 LOXL2

1.67e-04193253a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

KLHL11 LEMD3 UTRN

1.67e-04193253abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell(4)_Endothelial_cells-(4)_Lymph_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

CHRDL1 FLRT2 LAPTM5

1.69e-041942539735b86d3b2480a0b34d8aab8e7bd609d83c2454
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CHRDL1 FLRT2 LAPTM5

1.69e-041942539441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

CHRDL1 FLRT2 LAPTM5

1.72e-04195253de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ASPM PTPN12 IQGAP3

1.72e-04195253c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCellEndothelial_cells-Endothelial-B|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

CHRDL1 FLRT2 LAPTM5

1.74e-0419625336f95f9ef74eb951e41ef46fd136ceaef45208fc
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

CHRDL1 FLRT2 ALDH2

1.74e-0419625305530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

ASPM UTRN IQGAP3

1.74e-041962535905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ASPM MLANA IQGAP3

1.77e-04197253d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

CHRDL1 FLRT2 LAPTM5

1.77e-04197253a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCellnormal_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

CHRDL1 FLRT2 LAPTM5

1.77e-04197253c838d0f64e3b43a616a9e381b8139bfe9aa32da7
ToppCellLAM-Endothelial-LymEndo|Endothelial / Condition, Lineage and Cell class

CHRDL1 FLRT2 UTRN

1.80e-04198253ba64b1c95dfaa995045239d412e725596f6c482e
ToppCellsevere-Myeloid-Immature_Neutrophils_2|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ASPM ALDH2 IQGAP3

1.80e-04198253844f534551483c89ef789d1cfeb4680e54f794b2
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CHRDL1 FLRT2 LOXL2

1.82e-04199253a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

C22orf42 UTRN LAPTM5

1.82e-04199253379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

ASPM IQGAP3 KNOP1

1.82e-0419925338f1f612b29feb868322999ceeda78e52447ec4f
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ASPM TSBP1 IQGAP3

1.82e-04199253be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell11.5-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

CHRDL1 FLRT2 ALDH2

1.82e-041992531a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

ASPM IQGAP3 KNOP1

1.82e-04199253b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ASPM UTRN IQGAP3

1.85e-0420025328935053cd6918cd2e9f3e7691f8522216585cb6
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Stem_cells-Neuroepithelial_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ASPM UTRN IQGAP3

1.85e-04200253c88d8e67647c90d1fa2569516865a9fd766eaf1c
ToppCell356C-Lymphocytic-ILC-ILC-3|ILC / Donor, Lineage, Cell class and subclass (all cells)

KLHL11 KNOP1

5.32e-0461252d0b33a48ee2faf68b270f9279c630437f3e8b20b
ToppCellSevere-CD8+_T|Severe / Disease group and Cell class

ALDH2 EPHA1

1.23e-0393252433d23253b2102cf65df338a488554e5ab409d7e
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))|Striatum / BrainAtlas - Mouse McCarroll V32

ASPM IQGAP3

1.45e-031012520b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

UTRN LOXL2

1.62e-03107252fc07dd90f280191bd643398eac5c8273651d0925
ToppCell343B-Myeloid-Dendritic-cDC2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ALDH2 LAPTM5

1.68e-031092526e90d04c5094c7410d667dae80de3279bddd24bd
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQGAP3 EPHA1

1.97e-031182528d96a4879b28979fa04fbaeffa271a6b9ecbe867
ToppCellControl-CD8+_T_activated|World / Disease group and Cell class

RIPOR1 ALDH2

2.00e-0311925283c3e2bb71b947facbfbef635550901f33c8c26a
ToppCellASK440-Endothelial-Endothelium|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

RIPOR1 ALDH2

2.10e-031222522f76ec3b527e9528fbb006599a96e8bbdf9e0e62
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Hist1h2al)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ASPM IQGAP3

2.24e-031262526072996987f7b05949adb86c9433e3302c4441d2
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RIPOR1 LOXL2

2.24e-03126252518a6e4919981b556ce6b451a91270dba976bc75
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM IQGAP3

2.24e-031262528ae631694bbba40f64e55e2be8162d7a40eeadc5
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

IQGAP3 LAPTM5

2.27e-031272520750743574c2fca8df07e11d73e8b94579209609
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM IQGAP3

2.34e-03129252739b263296c28554967362060b154f7a95e1341d
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ASPM IQGAP3

2.34e-03129252ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ASPM IQGAP3

2.38e-03130252615c233c7c2600c1c2bc5cf5b1c501fc474564ef
DrugLatex

ASPM CHRDL1 MLANA IQGAP3

4.47e-05191244ctd:D007840
DrugDiethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A

RIPOR1 FLRT2 UTRN LOXL2

4.85e-051952444369_DN
DrugDeltaline [6836-11-9]; Down 200; 7.8uM; HL60; HT_HG-U133A

PTPN12 FLRT2 ALDH2 UTRN

5.04e-051972442171_DN
DrugLevocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A

MLANA FLRT2 UTRN LAPTM5

5.14e-051982443509_UP
Drug(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

CHRDL1 PTPN12 UTRN LOXL2

5.14e-051982446657_DN
DrugAcetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A

ALDH2 UTRN EPHA1 LAPTM5

5.25e-051992447461_UP
DrugRamipril [87333-19-5]; Down 200; 9.6uM; HL60; HT_HG-U133A

RIPOR1 FLRT2 ALDH2 UTRN

5.35e-052002446150_DN
Drugacetylspiramycin

ASPM CHRDL1

6.98e-0512242CID005282173
DrugGal 1

CHRDL1 ALDH2 LEMD3

1.03e-0487243CID000173707
DrugSM-5

CHRDL1 MLANA

2.00e-0420242CID000486034
Drugcarbohydrazide

CHRDL1 LOXL2

2.00e-0420242CID000073948
Drugcoprine

ALDH2 LOXL2

2.43e-0422242CID000108079
DrugAC1L1ABQ

ASPM CHRDL1

2.66e-0423242CID000000920
DrugNSC-85245

ASPM EPHA1

2.66e-0423242CID000257281
Drugphentermine

LOXL2 EPHA1

3.96e-0428242CID000004771
DrugL 012

CHRDL1 ALDH2

4.25e-0429242CID000126741
Drug3,4-dihydroxyphenylacetaldehyde

ALDH2 LOXL2

4.55e-0430242CID000119219
DrugFurazolidone-d4

ALDH2 LOXL2

4.55e-0430242CID000003435
DrugMometasone furoate [83919-23-7]; Up 200; 7.6uM; HL60; HG-U133A

PTPN12 FLRT2 METAP2

8.02e-041752431746_UP
Drug5-hydroxytryptophol

ALDH2 LOXL2

8.94e-0442242CID000009061
DrugGW8510; Down 200; 10uM; PC3; HT_HG-U133A

ASPM LEMD3 MAP4K3

8.99e-041822437067_DN
DrugCamptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A

ASPM LEMD3 MAP4K3

8.99e-041822433887_DN
Drug15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A

RIPOR1 EPHA1 KNOP1

8.99e-041822431231_DN
DrugGW8510; Down 200; 10uM; MCF7; HT_HG-U133A

ASPM LEMD3 KNOP1

9.13e-041832437062_DN
Drugovothiol A

ALDH2 MYO1A

9.81e-0444242CID000130131
DrugTrifluoperazine dihydrochloride [440-17-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A

KLHL11 LOXL2 EPHA1

9.87e-041882435442_UP
DrugR)salsolinol

ALDH2 LOXL2

1.03e-0345242CID000054455
Drug1,2,3-triazole

METAP2 LOXL2

1.03e-0345242CID000067516
DrugTrifluridine [70-00-8]; Down 200; 13.6uM; HL60; HT_HG-U133A

ASPM RIPOR1 FLRT2

1.03e-031912436136_DN
DrugFenbendazole [43210-67-9]; Down 200; 13.4uM; MCF7; HT_HG-U133A

PTPN12 UTRN LOXL2

1.03e-031912433888_DN
Drug17-AAG; Down 200; 1uM; ssMCF7; HG-U133A

RIPOR1 EZH1 LEMD3

1.03e-03191243521_DN
DrugAzathymine, 6 [932-53-6]; Down 200; 31.4uM; HL60; HT_HG-U133A

PTPN12 FLRT2 METAP2

1.03e-031912432466_DN
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A

CHRDL1 UTRN LOXL2

1.05e-031922434334_DN
Diseasecirrhosis of liver

ALDH2 TSBP1

4.92e-0513242EFO_0001422
DiseaseGraves disease

ALDH2 TSBP1

1.98e-0381242EFO_0004237
DiseaseSquamous cell carcinoma of esophagus

ALDH2 LOXL2

2.70e-0395242C0279626
Diseasevital capacity

RIPOR1 FLRT2 ALDH2 UTRN METAP2

2.79e-031236245EFO_0004312
Diseasepancreatic cancer (is_implicated_in)

ALDH2 MEN1

3.73e-03112242DOID:1793 (is_implicated_in)
Diseaseloneliness measurement

UTRN LAPTM5

4.55e-03124242EFO_0007865
Diseaseenergy intake

ALDH2 TSBP1

5.29e-03134242EFO_0003939
DiseaseStuttering

METAP2 MEN1

6.00e-03143242HP_0025268

Protein segments in the cluster

PeptideGeneStartEntry
KEEYLREKMLRCEWY

ATP6V1FNB

16

A0A1B0GUX0
REKMLRCEWYRKYGS

ATP6V1FNB

21

A0A1B0GUX0
RCEWYRKYGSMVKAK

ATP6V1FNB

26

A0A1B0GUX0
YELMKNCWAYDRARR

EPHA1

856

P21709
ERYEDYLCWVKMARS

C22orf42

221

Q6IC83
KWKYNRGRRKDDYCE

FLRT2

576

O43155
AMWRRYRAKKYLCKV

ASPM

2941

Q8IZT6
CVVLRYMKYRWTKEE

LEMD3

646

Q9Y2U8
AERSWLYLKGSYMRC

MEN1

221

O00255
YFGSYLRRDKLWICM

MAP4K3

76

Q8IVH8
CRRWLDRLGESKYLM

METAP2

416

P50579
WYCRRRNGYRALMDK

MLANA

46

Q16655
KIYRGWRCRTHYQLM

MYO1A

706

Q9UBC5
KCRSRYDGHRIWMYN

LOXL2

731

Q9Y4K0
LQRDYDRAMSWKYSR

KNOP1

416

Q1ED39
YQYLCRLEEAKRWME

IQGAP3

31

Q86VI3
AYRYCAERKRWMLLP

KLHL11

631

Q9NVR0
YCMFQDKKYRVGERW

CHRDL1

36

Q9BU40
VHKKMWREFRGCRYC

FAM74A4

101

Q5TZK3
KWDRINRMYSDRKGC

UTRN

1956

P46939
FKVYMFKCVWRCYRL

LAPTM5

201

Q13571
FEMGRKKCERYWPLY

PTPN12

136

Q05209
MVLKCLRYYAGWADK

ALDH2

141

P05091
CITYWKRKVKSEYMR

EZH1

11

Q92800
LKNIRKVYGRCMWYR

SEC63

46

Q9UGP8
KVYGRCMWYRLRLLK

SEC63

51

Q9UGP8
GEAMVCRRWQKKYQY

ZSWIM3

576

Q96MP5
RWARCKQSEMYISRY

TSBP1

26

Q5SRN2
DQYEICMKYGRQRWK

RIPOR1

226

Q6ZS17