Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN1 FBN2

4.48e-0512172GO:0030023
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN1 FBN2

6.17e-0514172GO:0097493
GeneOntologyMolecularFunctionprotein-cysteine S-palmitoyltransferase activity

ZDHHC6 ZDHHC24

2.19e-0426172GO:0019706
GeneOntologyMolecularFunctionprotein-cysteine S-acyltransferase activity

ZDHHC6 ZDHHC24

2.19e-0426172GO:0019707
GeneOntologyMolecularFunctionS-acyltransferase activity

ZDHHC6 ZDHHC24

2.93e-0430172GO:0016417
GeneOntologyMolecularFunctionpalmitoyltransferase activity

ZDHHC6 ZDHHC24

4.46e-0437172GO:0016409
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MUC6 FBN1 FBN2

5.07e-04188173GO:0005201
GeneOntologyMolecularFunctionionotropic glutamate receptor binding

NETO2 NETO1

8.82e-0452172GO:0035255
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

ZDHHC6 ZDHHC24 GLYATL1B

1.00e-03238173GO:0016747
GeneOntologyMolecularFunctioncell adhesion mediator activity

NTNG1 ITGA2

1.87e-0376172GO:0098631
GeneOntologyMolecularFunctionglutamate receptor binding

NETO2 NETO1

2.12e-0381172GO:0035254
GeneOntologyMolecularFunctionacyltransferase activity

ZDHHC6 ZDHHC24 GLYATL1B HECTD4

3.58e-03775174GO:0016746
GeneOntologyMolecularFunctionhormone activity

FBN1 FBN2

5.77e-03135172GO:0005179
GeneOntologyMolecularFunctionintegrin binding

FBN1 ITGA2

9.53e-03175172GO:0005178
GeneOntologyMolecularFunctioncell adhesion molecule binding

NTNG1 FBN1 ITGA2

1.33e-02599173GO:0050839
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

3.83e-064172GO:0035583
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

1.79e-058172GO:0071694
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2

3.50e-0511172GO:0035581
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2

4.96e-0513172GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2

4.96e-0513172GO:1900116
GeneOntologyBiologicalProcesspeptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine

ZDHHC6 ZDHHC24

1.75e-0424172GO:0018231
GeneOntologyBiologicalProcesspeptidyl-L-cysteine S-palmitoylation

ZDHHC6 ZDHHC24

1.75e-0424172GO:0018230
GeneOntologyBiologicalProcessprotein palmitoylation

ZDHHC6 ZDHHC24

3.33e-0433172GO:0018345
GeneOntologyBiologicalProcessregulation of nervous system process

NETO2 NETO1 ITGA2

3.74e-04175173GO:0031644
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

NETO2 NETO1

5.66e-0443172GO:2000463
GeneOntologyBiologicalProcessneurotransmitter receptor localization to postsynaptic specialization membrane

NETO2 NETO1

7.35e-0449172GO:0099645
GeneOntologyBiologicalProcessprotein localization to postsynaptic specialization membrane

NETO2 NETO1

7.35e-0449172GO:0099633
GeneOntologyBiologicalProcesspeptidyl-cysteine modification

ZDHHC6 ZDHHC24

7.65e-0450172GO:0018198
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2

4.83e-0513172GO:0001527
HumanPhenoAbnormal upper to lower segment ratio

FBN1 FBN2

8.32e-06392HP:0012772
HumanPhenoCrumpled ear

FBN1 FBN2

4.15e-05692HP:0009901
DomainFBN

FBN1 FBN2

1.81e-063152IPR011398
DomainCUB

NETO2 NETO1 CUBN

7.55e-0649153PF00431
DomainCUB

NETO2 NETO1 CUBN

8.03e-0650153SM00042
Domain-

NETO2 NETO1 CUBN

9.05e-06521532.60.120.290
DomainCUB

NETO2 NETO1 CUBN

9.58e-0653153PS01180
DomainCUB_dom

NETO2 NETO1 CUBN

1.19e-0557153IPR000859
DomainTB

FBN1 FBN2

1.26e-057152PF00683
Domain-

FBN1 FBN2

1.68e-0581523.90.290.10
DomainTB_dom

FBN1 FBN2

2.16e-059152IPR017878
DomainTB

FBN1 FBN2

2.16e-059152PS51364
DomainEGF

NTNG1 FBN1 FBN2 CUBN

2.99e-05235154SM00181
DomainEGF_3

NTNG1 FBN1 FBN2 CUBN

2.99e-05235154PS50026
DomainEGF-like_dom

NTNG1 FBN1 FBN2 CUBN

3.75e-05249154IPR000742
DomainEGF_1

NTNG1 FBN1 FBN2 CUBN

4.12e-05255154PS00022
DomainEGF_CA

FBN1 FBN2 CUBN

4.12e-0586153PF07645
DomainEGF-like_CS

NTNG1 FBN1 FBN2 CUBN

4.51e-05261154IPR013032
DomainEGF_2

NTNG1 FBN1 FBN2 CUBN

4.78e-05265154PS01186
DomainEGF_Ca-bd_CS

FBN1 FBN2 CUBN

5.91e-0597153IPR018097
DomainEGF_CA

FBN1 FBN2 CUBN

6.28e-0599153PS01187
DomainASX_HYDROXYL

FBN1 FBN2 CUBN

6.47e-05100153PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 FBN2 CUBN

7.69e-05106153IPR000152
DomainEGF_CA

FBN1 FBN2 CUBN

1.17e-04122153SM00179
DomainEGF-like_Ca-bd_dom

FBN1 FBN2 CUBN

1.23e-04124153IPR001881
Domainzf-DHHC

ZDHHC6 ZDHHC24

1.51e-0423152PF01529
DomainDHHC

ZDHHC6 ZDHHC24

1.79e-0425152PS50216
DomainZnf_DHHC_palmitoyltrfase

ZDHHC6 ZDHHC24

1.79e-0425152IPR001594
DomaincEGF

FBN1 FBN2

1.93e-0426152PF12662
DomaincEGF

FBN1 FBN2

1.93e-0426152IPR026823
DomainGrowth_fac_rcpt_

FBN1 FBN2 CUBN

2.42e-04156153IPR009030
DomainLDLR_class-A_CS

NETO2 NETO1

4.61e-0440152IPR023415
DomainLdl_recept_a

NETO2 NETO1

5.84e-0445152PF00057
Domain-

NETO2 NETO1

6.11e-04461524.10.400.10
DomainLDLRA_1

NETO2 NETO1

6.65e-0448152PS01209
DomainLDLa

NETO2 NETO1

6.93e-0449152SM00192
DomainLDLRA_2

NETO2 NETO1

6.93e-0449152PS50068
DomainLDrepeatLR_classA_rpt

NETO2 NETO1

6.93e-0449152IPR002172
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2

8.40e-052582M39713
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2

1.39e-043282MM14854
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2

1.86e-043782M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2

2.07e-043982MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2

2.63e-044482M26969
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

FBN1 ITGA2 FBN2

3.17e-0425883MM14572
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

FBN1 ITGA2 FBN2

4.94e-0430083M610
PathwayPID_INTEGRIN1_PATHWAY

FBN1 ITGA2

5.94e-046682M18
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

FBN1 ITGA2

7.86e-047682MM14867
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

FBN1 ITGA2

9.83e-048582M16441
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

FBN1 FBN2

1.76e-0311482MM14571
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

FBN1 FBN2

2.64e-0314082M587
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC6 CUBN

8.17e-0325082M27554
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

PLA2R1 CUBN

1.83e-0238182M48063
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

2.25e-07217212399449
Pubmed

A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain.

NETO2 NETO1

2.25e-07217211943477
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

2.25e-07217221851253
Pubmed

Fibrillin-1 mutations causing Weill-Marchesani syndrome and acromicric and geleophysic dysplasias disrupt heparan sulfate interactions.

FBN1 FBN2

2.25e-07217223133647
Pubmed

Fibrillins can co-assemble in fibrils, but fibrillin fibril composition displays cell-specific differences.

FBN1 FBN2

2.25e-07217212429739
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

2.25e-0721728791520
Pubmed

Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis.

FBN1 FBN2

2.25e-07217224833718
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

2.25e-07217230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

2.25e-07217221440062
Pubmed

Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices.

FBN1 FBN2

2.25e-0721728120105
Pubmed

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2.

FBN1 FBN2

2.25e-07217235419902
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

2.25e-07217215131124
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

2.25e-0721728307578
Pubmed

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

FBN1 FBN2

2.25e-07217216407178
Pubmed

Neto auxiliary protein interactions regulate kainate and NMDA receptor subunit localization at mossy fiber-CA3 pyramidal cell synapses.

NETO2 NETO1

2.25e-07217224403160
Pubmed

Fibrillin assembly: dimer formation mediated by amino-terminal sequences.

FBN1 FBN2

2.25e-07217210504303
Pubmed

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

FBN1 FBN2

2.25e-0721721852206
Pubmed

Expression of Btcl2, a novel member of Btcl gene family, during development of the central nervous system.

NETO2 NETO1

2.25e-07217215464227
Pubmed

N-terminal domains of fibrillin 1 and fibrillin 2 direct the formation of homodimers: a possible first step in microfibril assembly.

FBN1 FBN2

2.25e-07217210359653
Pubmed

NETO1 Guides Development of Glutamatergic Connectivity in the Hippocampus by Regulating Axonal Kainate Receptors.

NETO2 NETO1

2.25e-07217228680963
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

2.25e-0721727744963
Pubmed

Nonselective assembly of fibrillin 1 and fibrillin 2 in the rodent ocular zonule and in cultured cells: implications for Marfan syndrome.

FBN1 FBN2

2.25e-07217224265020
Pubmed

Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development.

FBN1 FBN2

2.25e-07217212524050
Pubmed

In vivo studies of mutant fibrillin-1 microfibrils.

FBN1 FBN2

2.25e-07217220529844
Pubmed

NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation.

NETO2 NETO1

2.25e-07217231044365
Pubmed

Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction.

NETO2 NETO1

2.25e-07217230770891
Pubmed

Immunohistochemical expression of fibrillin-1 and fibrillin-2 during tooth development.

FBN1 FBN2

2.25e-07217225524144
Pubmed

Fibrillin microfibrils in bone physiology.

FBN1 FBN2

2.25e-07217226408953
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

2.25e-07217220404337
Pubmed

Arg-Gly-Asp-containing domains of fibrillins-1 and -2 distinctly regulate lung fibroblast migration.

FBN1 FBN2

2.25e-07217218006876
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

NTNG1 NETO2 NETO1 CUBN

2.80e-0711717417145500
Pubmed

Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.

FBN1 FBN2

6.74e-07317210825173
Pubmed

Neto2 Assembles with Kainate Receptors in DRG Neurons during Development and Modulates Neurite Outgrowth in Adult Sensory Neurons.

NETO2 NETO1

6.74e-07317228235897
Pubmed

Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.

FBN1 FBN2

6.74e-07317230201140
Pubmed

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.

FBN1 FBN2

6.74e-07317220855508
Pubmed

Neto auxiliary proteins control both the trafficking and biophysical properties of the kainate receptor GluK1.

NETO2 NETO1

6.74e-07317226720915
Pubmed

The auxiliary subunits Neto1 and Neto2 have distinct, subunit-dependent effects at recombinant GluK1- and GluK2-containing kainate receptors.

NETO2 NETO1

1.35e-06417226277340
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN1 FBN2

1.35e-06417212429738
Pubmed

Comprehensive genetic analysis of relevant four genes in 49 patients with Marfan syndrome or Marfan-related phenotypes.

FBN1 FBN2

1.35e-06417216835936
Pubmed

Human eye development is characterized by coordinated expression of fibrillin isoforms.

FBN1 FBN2

1.35e-06417225406291
Pubmed

Extracellular microfibrils control osteoblast-supported osteoclastogenesis by restricting TGF{beta} stimulation of RANKL production.

FBN1 FBN2

1.35e-06417220729550
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FBN2

1.35e-06417225034023
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

FBN1 ITGA2 FBN2

1.87e-065017323658023
Pubmed

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.

FBN1 FBN2

2.25e-06517226601954
Pubmed

Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition.

NETO2 NETO1

2.25e-06517228854365
Pubmed

Relaxin regulates fibrillin 2, but not fibrillin 1, mRNA and protein expression by human dermal fibroblasts and murine fetal skin.

FBN1 FBN2

2.25e-06517212590922
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

FBN1 FBN2

2.25e-06517217255108
Pubmed

Development, composition, and structural arrangements of the ciliary zonule of the mouse.

FBN1 FBN2

2.25e-06517223493297
Pubmed

POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.

FBN1 FBN2

2.25e-06517234411563
Pubmed

Of mice and Marfan: genetic linkage analyses of the fibrillin genes, Fbn1 and Fbn2, in the mouse genome.

FBN1 FBN2

3.37e-0661727873879
Pubmed

Neto1 is an auxiliary subunit of native synaptic kainate receptors.

NETO2 NETO1

3.37e-06617221734292
Pubmed

Regulation of limb patterning by extracellular microfibrils.

FBN1 FBN2

4.72e-06717211470817
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

MUC6 FBN1 FBN2

5.43e-067117333541421
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

FBN1 FBN2

6.29e-06817223055981
Pubmed

Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.

FBN1 FBN2

6.29e-06817231201465
Pubmed

Targeting of bone morphogenetic protein growth factor complexes to fibrillin.

FBN1 FBN2

6.29e-06817218339631
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN1 FBN2

8.08e-06917212122015
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN1 FBN2

8.08e-06917238844137
Pubmed

Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.

FBN1 FBN2

1.01e-051017230738849
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

NTNG1 NETO2 NETO1

1.15e-059117328558017
Pubmed

Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.

FBN1 FBN2

1.48e-051217226405179
Pubmed

A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development.

FBN1 FBN2

1.48e-051217236779913
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

NETO2 PLA2R1 ZDHHC6 FBN1 ITGA2 FBN2

1.49e-05120117635696571
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

NTNG1 NETO2 NETO1

3.04e-0512617316284245
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

FBN1 FBN2

3.42e-051817239040056
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

FBN1 FBN2

3.42e-051817235503090
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 FBN2

7.26e-052617234189436
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

FBN1 FBN2

9.70e-053017232882513
Pubmed

Heritable Thoracic Aortic Disease Overview

FBN1 FBN2

9.70e-053017220301299
Pubmed

Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia.

FBN1 FBN2

1.04e-043117225762570
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

PLA2R1 ZDHHC6 ITGA2 FBN2

1.27e-0455217410737800
Pubmed

O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.

FBN1 FBN2

1.40e-043617235167946
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

FBN1 FBN2

1.48e-043717234323105
Pubmed

Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis.

FBN1 FBN2

1.73e-044017230578393
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

FBN1 FBN2

2.94e-045217230389913
InteractionMFAP2 interactions

FBN1 FBN2

3.88e-0512162int:MFAP2
InteractionZDHHC15 interactions

MUC6 FBN1 FBN2

1.23e-04125163int:ZDHHC15
InteractionNTN5 interactions

FBN1 FBN2

1.61e-0424162int:NTN5
InteractionELN interactions

FBN1 FBN2

2.37e-0429162int:ELN
InteractionTMED6 interactions

NETO2 ITGA2

4.30e-0439162int:TMED6
InteractionST14 interactions

NETO2 FBN1 FBN2

5.42e-04207163int:ST14
InteractionBTNL8 interactions

NETO2 ITGA2

6.26e-0447162int:BTNL8
InteractionFBN1 interactions

FBN1 FBN2

7.37e-0451162int:FBN1
InteractionMFAP5 interactions

FBN1 FBN2

7.66e-0452162int:MFAP5
InteractionZFP41 interactions

FBN1 FBN2

9.19e-0457162int:ZFP41
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC6 ZDHHC24

4.71e-05248276
CoexpressionBROWNE_HCMV_INFECTION_24HR_DN

FBN1 ITGA2 FBN2

8.81e-05145163M14098
CoexpressionNABA_ECM_GLYCOPROTEINS

NTNG1 FBN1 FBN2

1.99e-04191163MM17059
CoexpressionGSE29615_CTRL_VS_LAIV_FLU_VACCINE_PBMC_DN

N4BP2L2 CACNA1G TTC21A

1.99e-04191163M4924
CoexpressionNABA_ECM_GLYCOPROTEINS

NTNG1 FBN1 FBN2

2.15e-04196163M3008
CoexpressionGSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_DN

NETO2 NETO1 FBN2

2.24e-04199163M7443
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

FBN1 ITGA2 FBN2

2.28e-04200163M5930
CoexpressionLIAO_METASTASIS

NETO2 N4BP2L2 ZDHHC24 ITGA2

2.66e-04540164M13809
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

NTNG1 PLA2R1 ZDHHC6

2.70e-04212163M39221
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

CACNA1G FBN1 FBN2

9.81e-05122163gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

NTNG1 CACNA1G FBN1

1.05e-04125163gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500

PLA2R1 CACNA1G FBN1 FBN2

1.22e-04357164gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

NTNG1 NETO2 CACNA1G FBN1 FBN2

1.97e-04773165gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

NTNG1 NETO2 CACNA1G FBN1 FBN2

2.02e-04777165gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

NTNG1 CACNA1G FBN1

2.03e-04156163gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 NETO1 PLA2R1 ZDHHC6

3.11e-0715517490e629681a72baacc7981b82883866a487638dbc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

2.63e-05155173e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

2.63e-051551735a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellTCGA-Kidney-Solid_Tissue_Normal-Kidney-Kidney_normal_tissue-5|TCGA-Kidney / Sample_Type by Project: Shred V9

NTNG1 MUC6 PLA2R1

2.79e-0515817334b284a62cc3fb90429ce579fd8cb8a60178091b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

2.84e-05159173fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

2.84e-05159173aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

2.84e-051591738bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.35e-05168173fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.35e-05168173e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.35e-05168173315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.47e-0517017360bbd738c12e64e483485586c30057304884f5a6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.59e-051721736c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.59e-05172173381ae1c3c07d0a424f43455ec571653b192a946a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.71e-05174173dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NTNG1 PLA2R1 ZDHHC6

3.78e-05175173a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

PLA2R1 CACNA1G FBN2

3.84e-05176173852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PLA2R1 CACNA1G FBN2

3.84e-05176173d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.91e-051771734d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

3.97e-05178173edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.04e-051791737394e77e665bf16d3733df91bb12907be460ab44
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.04e-05179173c1c0b7186a0eab8c76404b95f1cf8d64b1b45cb1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.11e-05180173d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

NETO1 FBN1 FBN2

4.18e-05181173bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.18e-051811735bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.18e-051811738e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.25e-05182173cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

NTNG1 PLA2R1 ZDHHC6

4.32e-05183173fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.32e-051831733c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.32e-051831737c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.32e-05183173612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.32e-05183173848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.32e-05183173eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.32e-051831739c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTNG1 PLA2R1 FBN1

4.39e-0518417396a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTNG1 PLA2R1 FBN1

4.39e-05184173780eb72da43527f0c72effac3423ec7384f05f20
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.39e-051841737294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NTNG1 PLA2R1 FBN1

4.39e-05184173fea4fe648e9749177d0783443dc26a7df5807883
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.46e-051851739197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.46e-05185173b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.46e-05185173ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.53e-051861731094c7140131454b2583200e1c01e81ccab3db23
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1G FBN1 FBN2

4.60e-051871735258674d0346e5c51a4b965efcdc1790c970845d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.60e-0518717324c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.68e-051881739db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.68e-05188173047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 CACNA1G FBN1

4.83e-0519017317a73a658fb30a4322b31e38db7b240023738f29
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.83e-0519017392710caaff05123cf8e909319d7ac441d9b31a66
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 CACNA1G FBN1

4.83e-051901738cb950effc449ae59a915132ecc079be54d1acfe
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 CACNA1G FBN1

4.83e-051901735dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NTNG1 FBN1 ITGA2

4.90e-051911736688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NTNG1 FBN1 ITGA2

4.98e-0519217399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 FBN1 FBN2

4.98e-051921738937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 FBN1 FBN2

4.98e-05192173ac1477433704573f95111eee6263b93668d2845e
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NETO1 PLA2R1 FBN2

4.98e-05192173dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

4.98e-05192173ef0aba777072429a6ab7dcfcc305673975946580
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2R1 FBN1 FBN2

4.98e-05192173e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 TTC21A ITGA2

5.06e-05193173ea345d34440b25f65358a53dc72831998d1c3620
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

5.06e-051931733eaa0461618582a1754400624350d269d24e750a
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NETO2 NETO1 FBN2

5.06e-05193173010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

NTNG1 FBN1 ITGA2

5.06e-05193173ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1 ZDHHC6

5.13e-0519417343eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

NTNG1 FBN1 ITGA2

5.21e-0519517361c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1G FBN1 FBN2

5.37e-051971739af431323da6d099459b7360af40e5df998cffbd
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

NTNG1 PLA2R1 FBN1

5.45e-05198173df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

NTNG1 FBN1 ITGA2

5.45e-051981733ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

NTNG1 N4BP2L2 ITGA2

5.45e-05198173e0e47cf65774191981840b22905b2094b95abe0f
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1G FBN1 FBN2

5.45e-05198173a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NTNG1 FBN1 ITGA2

5.62e-0520017334f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NTNG1 FBN1 ITGA2

5.62e-052001738c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Cadm2+,_not_selective)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TTC21A CUBN

1.20e-04431727027858b46c0aabec290ed3888201a1b39e10552
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Cadm2+,_not_selective)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TTC21A CUBN

1.20e-04431720282410243ba125ec13fd6af737ddf952e493280
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MUC6 CUBN

4.38e-048217272d5a55ca7c03e9c54f865524e206b288f242017
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MUC6 CUBN

4.38e-0482172ea3bdd7b871269eacb81167c6cf59a0e21bf6d83
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Mgp_(Gkn3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MUC6 CUBN

4.38e-0482172e500582511814a067852dc3bd78d19937c28ba60
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

PLA2R1 FBN1

1.16e-03134172a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

PLA2R1 FBN1

1.16e-031341729458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NETO1 MUC6

1.30e-0314217266135fee18448cc09a78bc6ede05afd63c72ae21
ToppCellTCGA-Uterus|World / Sample_Type by Project: Shred V9

CACNA1G FBN2

1.34e-031441727efb45286ebf2dbfb9125fd6373f28dccb029a2e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 ITGA2

1.43e-031491727e295b2b82dea0754e98f8cef788e2781e5d641f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 ITGA2

1.43e-03149172b4f77dc5f9d08b249fe5cd9a0acf86308c528ef4
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-7|TCGA-Bladder / Sample_Type by Project: Shred V9

CACNA1G CUBN

1.45e-031501723ab17045b2c43bb4f0ebba6aa0cfb22e076a24f9
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-GC_B_(II)|lymph-node_spleen / Manually curated celltypes from each tissue

NTNG1 TTC21A

1.49e-031521724f690aed23338687bdefc47e8a2f3d1fdb2b6447
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NTNG1 PLA2R1

1.51e-03153172c1335e7d7407412431ed4d8c7dfcb2c6086d8483
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP47 ITGA2

1.53e-03154172ce4b1e878cd88065fbfd2df18caf19703fec37d8
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP47 NTNG1

1.55e-03155172441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-12|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NETO1 TTC21A

1.57e-031561727ece590fd8f29382e349dd0e5e016d2926aeb518
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

NTNG1 FBN1

1.59e-03157172f147e24f2ece82e1c54750868954d09b3c461804
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NTNG1 FBN1

1.61e-03158172e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC6 FBN2

1.63e-031591724000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC6 FBN2

1.63e-031591727619d0d49738dd08daf01b42664691a5323aa793
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CFAP47 GLYATL1B

1.65e-03160172654d5908d9916d3616eb72871e20ed8417e17987
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CACNA1G FBN2

1.65e-03160172636127753e3a22831f39d4c8170df40901e4329d
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CACNA1G FBN2

1.65e-03160172cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NETO2 NETO1

1.67e-03161172dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN2 CUBN

1.69e-0316217234b4cd3d2258f88dfbd6d32abd1db87aff8a6b6f
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

PLA2R1 FBN1

1.71e-031631721a8c79903ed416f286ebe8a9922233affbc55d82
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN2 CUBN

1.71e-0316317256b8668dbf06faa6866ec71f29b92907b73f074d
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

MUC6 TTC21A

1.71e-0316317243194c6127df1ce3d29242f719645de3c11fd7c0
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-7|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PLA2R1 FBN2

1.73e-0316417281c41e1b5535b7969bcf6fa2456f828e8e8e2ff7
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FBN2 GLYATL1B

1.73e-03164172ed7e0c8ccad7d19b9cc72d70391936ff5e698f28
ComputationalMetal / Ca ion binding.

FBN1 ITGA2 FBN2

9.91e-0513383MODULE_324
ComputationalAdhesion molecules.

FBN1 ITGA2 FBN2

1.18e-0414183MODULE_122
DrugGABA methylester

FBN1 ITGA2

9.70e-067162CID000018614
DrugRgd Peptide

TTC21A FBN1 ITGA2 FBN2

1.95e-05239164CID000104802
DrugTAAD

FBN1 FBN2

9.65e-0521162CID000133445
Druglosartan

NETO1 FBN1 ITGA2 FBN2

1.16e-04378164CID000003961
Drugcyclohexene oxide

FBN1 ITGA2

1.61e-0427162CID000009246
Drugdimethyl acetal

NETO1 ITGA2

1.99e-0430162CID000010795
Drugrosavin

FBN1 FBN2

2.27e-0432162ctd:C529148
Drugisodesmosine

FBN1 FBN2

2.41e-0433162CID000013811
DrugNSC49080

FBN1 FBN2

2.41e-0433162CID000002192
DrugRapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A

NTNG1 FBN1 ITGA2

2.73e-041851634445_UP
DrugNitrendipine [39562-70-4]; Up 200; 11uM; HL60; HT_HG-U133A

MUC6 CACNA1G FBN1

3.05e-041921633087_UP
Drug2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A

NTNG1 MUC6 CACNA1G

3.10e-041931632682_UP
DrugHydralazine hydrochloride [304-20-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

MUC6 FBN1 FBN2

3.19e-041951634746_UP
DrugProbucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A

PLA2R1 FBN1 ITGA2

3.19e-041951635261_UP
DrugXylometazoline hydrochloride [1218-35-5]; Up 200; 14.2uM; MCF7; HT_HG-U133A

MUC6 PLA2R1 CACNA1G

3.24e-041961632270_UP
DrugCeftazidime pentahydrate [78439-06-2]; Up 200; 6.2uM; MCF7; HT_HG-U133A

PLA2R1 FBN1 CUBN

3.34e-041981635473_UP
DrugAminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

MUC6 CACNA1G FBN1

3.34e-041981632313_UP
Drugpotassium bromide

NETO1 ITGA2

4.71e-0446162CID000253877
Drugfuniferine N-oxide

FBN1 FBN2

5.34e-0449162CID000191631
Drugdesmosine

FBN1 FBN2

6.25e-0453162CID000025435
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2

9.37e-073172DOID:65 (implicated_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

1.87e-064172DOID:0060249 (is_implicated_in)
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2

4.23e-0453172C4707243
Diseasecentral corneal thickness

FBN1 ITGA2 FBN2

6.94e-04309173EFO_0005213
Diseasemucocutaneous lymph node syndrome

NTNG1 CUBN

8.68e-0476172EFO_0004246
Diseaseserum alanine aminotransferase measurement

NTNG1 N4BP2L2 FBN1 HECTD4

1.31e-03869174EFO_0004735
Diseasecorneal resistance factor

FBN1 ITGA2 FBN2

2.06e-03451173EFO_0010067

Protein segments in the cluster

PeptideGeneStartEntry
CNGLQNCVYPWDENH

NETO1

311

Q8TDF5
QYTQEANCTWHYQPC

MUC6

1146

Q6W4X9
YIDQWCNPGNQAFHY

HECTD4

186

Q9Y4D8
CGPLWAQQCGNQYYT

ITGA2

131

P17301
YPNPYSENQHCNWTI

CUBN

1296

O60494
WNQYYTNCSAGEHNP

CACNA1G

316

O43497
SCPQGYLQHYQWNQC

FBN1

2591

P35555
SCQWHQWNCYPQNLV

GLYATL1B

286

A0A0U1RQE8
RCGCPQGYIQHYQWN

FBN2

2636

P35556
YNRQNCCAQFQWQPV

CFAP47

876

Q6ZTR5
NSWHYGCQPNVCDNE

NTNG1

456

Q9Y2I2
CNGVQNCAYPWDENH

NETO2

316

Q8NC67
THCEPGWNPYNRNCY

PLA2R1

376

Q13018
DHHCPWINNCCGYQN

ZDHHC6

126

Q9H6R6
NYCRGIYCWHIGQPN

TTC21A

1031

Q8NDW8
QGWAYCYQCQSQVPP

ZDHHC24

91

Q6UX98
GYYVNNCHVNWNCMT

N4BP2L2

316

Q92802