Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	amide transport	CACNA1D SIDT2 TRPA1 ABCA13 RAB8B SLC19A3 CPT1A SLC14A2 AQP9 EPHA5	1.34e-05	420	89	10	GO:0042886
GeneOntologyBiologicalProcess	glycolytic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.14e-04	110	89	5	GO:0006096
GeneOntologyBiologicalProcess	ADP catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.35e-04	114	89	5	GO:0046032
GeneOntologyBiologicalProcess	purine nucleoside diphosphate catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.53e-04	117	89	5	GO:0009137
GeneOntologyBiologicalProcess	purine ribonucleoside diphosphate catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.53e-04	117	89	5	GO:0009181
GeneOntologyBiologicalProcess	pyridine nucleotide catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.66e-04	119	89	5	GO:0019364
GeneOntologyBiologicalProcess	ADP metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.72e-04	120	89	5	GO:0046031
GeneOntologyBiologicalProcess	ribonucleoside diphosphate catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.79e-04	121	89	5	GO:0009191
GeneOntologyBiologicalProcess	pyridine-containing compound catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	1.93e-04	123	89	5	GO:0072526
GeneOntologyBiologicalProcess	nucleoside diphosphate catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	2.01e-04	124	89	5	GO:0009134
GeneOntologyBiologicalProcess	carbohydrate catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3 DERA	2.06e-04	196	89	6	GO:0016052
GeneOntologyBiologicalProcess	nicotinamide nucleotide metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3 DERA	2.42e-04	202	89	6	GO:0046496
GeneOntologyBiologicalProcess	pyridine nucleotide metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3 DERA	2.42e-04	202	89	6	GO:0019362
GeneOntologyBiologicalProcess	purine nucleoside diphosphate metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	2.69e-04	132	89	5	GO:0009135
GeneOntologyBiologicalProcess	purine ribonucleoside diphosphate metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	2.69e-04	132	89	5	GO:0009179
GeneOntologyBiologicalProcess	response to carbon dioxide	A2M TRPA1	2.73e-04	6	89	2	GO:0010037
GeneOntologyBiologicalProcess	nucleotide catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3 DERA	2.84e-04	208	89	6	GO:0009166
GeneOntologyBiologicalProcess	pyridine-containing compound metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3 DERA	2.99e-04	210	89	6	GO:0072524
GeneOntologyBiologicalProcess	nucleoside phosphate catabolic process	ENO4 GALT HKDC1 MTCH2 STAT3 DERA	3.47e-04	216	89	6	GO:1901292
GeneOntologyBiologicalProcess	pyruvate metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	3.76e-04	142	89	5	GO:0006090
GeneOntologyBiologicalProcess	ribonucleoside diphosphate metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	3.88e-04	143	89	5	GO:0009185
GeneOntologyBiologicalProcess	nucleoside diphosphate metabolic process	ENO4 GALT HKDC1 MTCH2 STAT3	4.69e-04	149	89	5	GO:0009132
Domain	Recoverin	HPCA NCALD HPCAL1	2.89e-05	13	89	3	IPR028846
Domain	PLAC	ADAMTS10 ADAMTS6 ADAMTS18	3.67e-05	14	89	3	PF08686
Domain	PLAC	ADAMTS10 ADAMTS6 ADAMTS18	9.59e-05	19	89	3	PS50900
Domain	PLAC	ADAMTS10 ADAMTS6 ADAMTS18	9.59e-05	19	89	3	IPR010909
Domain	fn3	IGSF22 TRIM42 PTPRM EPHA2 OBSCN EPHA5	1.25e-04	162	89	6	PF00041
Domain	ADAM_spacer1	ADAMTS10 ADAMTS6 ADAMTS18	1.73e-04	23	89	3	IPR010294
Domain	ADAM_spacer1	ADAMTS10 ADAMTS6 ADAMTS18	1.73e-04	23	89	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS10 ADAMTS6 ADAMTS18	1.97e-04	24	89	3	IPR013273
Domain	FN3	IGSF22 TRIM42 PTPRM EPHA2 OBSCN EPHA5	2.56e-04	185	89	6	SM00060
Domain	FN3	IGSF22 TRIM42 PTPRM EPHA2 OBSCN EPHA5	3.78e-04	199	89	6	PS50853
Domain	DEAD/DEAH_box_helicase_dom	DHX37 EIF4A1 DHX38 RECQL	4.08e-04	73	89	4	IPR011545
Domain	DEAD	DHX37 EIF4A1 DHX38 RECQL	4.08e-04	73	89	4	PF00270
Domain	Carn_acyltransf	CHAT CPT1A	4.64e-04	7	89	2	PF00755
Domain	ACYLTRANSF_C_1	CHAT CPT1A	4.64e-04	7	89	2	PS00439
Domain	Carn_acyl_trans	CHAT CPT1A	4.64e-04	7	89	2	IPR000542
Domain	ACYLTRANSF_C_2	CHAT CPT1A	4.64e-04	7	89	2	PS00440
Domain	FN3_dom	IGSF22 TRIM42 PTPRM EPHA2 OBSCN EPHA5	4.91e-04	209	89	6	IPR003961
Domain	S1	PNPT1 EIF2S1	6.17e-04	8	89	2	PF00575
Domain	Peptidase_M12B_N	ADAMTS10 ADAMTS6 ADAMTS18	8.44e-04	39	89	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS10 ADAMTS6 ADAMTS18	8.44e-04	39	89	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS10 ADAMTS6 ADAMTS18	9.10e-04	40	89	3	PS00427
Domain	Reprolysin	ADAMTS10 ADAMTS6 ADAMTS18	9.10e-04	40	89	3	PF01421
Domain	ADAM_MEPRO	ADAMTS10 ADAMTS6 ADAMTS18	9.10e-04	40	89	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS10 ADAMTS6 ADAMTS18	9.10e-04	40	89	3	PS50214
Domain	Peptidase_M12B	ADAMTS10 ADAMTS6 ADAMTS18	9.10e-04	40	89	3	IPR001590
Domain	Disintegrin_dom	ADAMTS10 ADAMTS6 ADAMTS18	9.78e-04	41	89	3	IPR001762
Domain	A2M_N	A2M PZP	9.86e-04	10	89	2	PF01835
Domain	A2M_N	A2M PZP	9.86e-04	10	89	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	A2M PZP	9.86e-04	10	89	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	A2M PZP	9.86e-04	10	89	2	PS00477
Domain	A2M	A2M PZP	9.86e-04	10	89	2	PF00207
Domain	A2M_N_2	A2M PZP	9.86e-04	10	89	2	IPR011625
Domain	A2M_comp	A2M PZP	9.86e-04	10	89	2	IPR011626
Domain	S1	PNPT1 EIF2S1	9.86e-04	10	89	2	PS50126
Domain	A2M_N_2	A2M PZP	9.86e-04	10	89	2	PF07703
Domain	A2M_recep	A2M PZP	9.86e-04	10	89	2	PF07677
Domain	A2M_comp	A2M PZP	9.86e-04	10	89	2	PF07678
Domain	Macroglobln_a2	A2M PZP	9.86e-04	10	89	2	IPR001599
Domain	S1	PNPT1 EIF2S1	1.44e-03	12	89	2	SM00316
Domain	S1_dom	PNPT1 EIF2S1	1.44e-03	12	89	2	IPR022967
Domain	S1_domain	PNPT1 EIF2S1	1.44e-03	12	89	2	IPR003029
Domain	Helicase_C	DHX37 EIF4A1 DHX38 RECQL	1.71e-03	107	89	4	PF00271
Domain	HELICc	DHX37 EIF4A1 DHX38 RECQL	1.71e-03	107	89	4	SM00490
Domain	Helicase_C	DHX37 EIF4A1 DHX38 RECQL	1.77e-03	108	89	4	IPR001650
Domain	HELICASE_CTER	DHX37 EIF4A1 DHX38 RECQL	1.83e-03	109	89	4	PS51194
Domain	HELICASE_ATP_BIND_1	DHX37 EIF4A1 DHX38 RECQL	1.83e-03	109	89	4	PS51192
Domain	DEXDc	DHX37 EIF4A1 DHX38 RECQL	1.83e-03	109	89	4	SM00487
Domain	Helicase_ATP-bd	DHX37 EIF4A1 DHX38 RECQL	1.89e-03	110	89	4	IPR014001
Domain	RECEPTOR_TYR_KIN_V_2	EPHA2 EPHA5	1.97e-03	14	89	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHA2 EPHA5	1.97e-03	14	89	2	PS00790
Domain	Eph_TM	EPHA2 EPHA5	1.97e-03	14	89	2	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHA2 EPHA5	1.97e-03	14	89	2	IPR001426
Domain	EPH_lbd	EPHA2 EPHA5	1.97e-03	14	89	2	SM00615
Domain	Ephrin_lbd	EPHA2 EPHA5	1.97e-03	14	89	2	PF01404
Domain	EphA2_TM	EPHA2 EPHA5	1.97e-03	14	89	2	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHA2 EPHA5	1.97e-03	14	89	2	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHA2 EPHA5	1.97e-03	14	89	2	IPR001090
Domain	EPH_LBD	EPHA2 EPHA5	1.97e-03	14	89	2	PS51550
Domain	DUF1605	DHX37 DHX38	2.91e-03	17	89	2	IPR011709
Domain	OB_NTP_bind	DHX37 DHX38	2.91e-03	17	89	2	PF07717
Domain	HA2	DHX37 DHX38	3.27e-03	18	89	2	SM00847
Domain	HA2	DHX37 DHX38	3.27e-03	18	89	2	PF04408
Domain	Helicase-assoc_dom	DHX37 DHX38	3.27e-03	18	89	2	IPR007502
Domain	Terpenoid_cyclase/PrenylTrfase	A2M PZP	3.27e-03	18	89	2	IPR008930
Domain	TSP_1	ADAMTS10 ADAMTS6 ADAMTS18	3.38e-03	63	89	3	PF00090
Domain	TSP1	ADAMTS10 ADAMTS6 ADAMTS18	3.69e-03	65	89	3	SM00209
Domain	TSP1_rpt	ADAMTS10 ADAMTS6 ADAMTS18	3.69e-03	65	89	3	IPR000884
Domain	TSP1	ADAMTS10 ADAMTS6 ADAMTS18	3.69e-03	65	89	3	PS50092
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	CS HYOU1 NCKAP1 EIF2S1 DHX37 VPS13C EIF4A1 POLR2B DHX38 NCAPD2 CYB5R3 NOC4L TLN2 RECQL ANAPC7 NIPBL MTCH2	1.53e-07	1425	91	17	30948266
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	PNPT1 HYOU1 NCKAP1 EIF2S1 EIF4A1 POLR2B DHX38 NCAPD2 EIF5A2 RECQL PAM16 CPT1A NIPBL MTCH2 STAT3 SON	7.58e-07	1415	91	16	28515276
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PNPT1 HYOU1 NCKAP1 DHX37 EIF4A1 DHX38 NCAPD2 NOC4L RECQL NIPBL SON	1.14e-06	653	91	11	22586326
Pubmed	Identification of Ca2+-dependent binding partners for the neuronal calcium sensor protein neurocalcin delta: interaction with actin, clathrin and tubulin.	HPCA NCALD HPCAL1	2.05e-06	10	91	3	11964161
Pubmed	Ephrin-A5 and EphA5 interaction induces synaptogenesis during early hippocampal development.	CACNA1D GRIN2B EPHA5	2.82e-06	11	91	3	20824214
Pubmed	Study of FOXO1-interacting proteins using TurboID-based proximity labeling technology.	A2M XIRP2 EIF2S1 EIF4A1 SLC19A3 LCOR CA6	3.66e-06	243	91	7	36964488
Pubmed	Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.	NCKAP1 GRIN2B GRINA	6.18e-06	14	91	3	15749123
Pubmed	A genetic polymorphism in a functional domain of human pregnancy zone protein: the bait region. Genomic structure of the bait domains of human pregnancy zone protein and alpha 2 macroglobulin.	A2M PZP	6.77e-06	2	91	2	1692292
Pubmed	Functional and molecular expression of AQP9 channel and UT-A transporter in normal and preeclamptic human placentas.	SLC14A2 AQP9	6.77e-06	2	91	2	16480766
Pubmed	Differential binding properties of human pregnancy zone protein- and alpha2-macroglobulin-proteinase complexes to low-density lipoprotein receptor-related protein.	A2M PZP	6.77e-06	2	91	2	11811950
Pubmed	Neurocalcin family: a novel calcium-binding protein abundant in bovine central nervous system.	HPCA HPCAL1	6.77e-06	2	91	2	8387172
Pubmed	ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.	ADAMTS10 ADAMTS6	6.77e-06	2	91	2	27779234
Pubmed	A proteomics analysis reveals that A2M might be regulated by STAT3 in persistent allergic rhinitis.	A2M STAT3	6.77e-06	2	91	2	27228572
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	NCKAP1 EIF2S1 DHX37 EIF4A1 POLR2B DHX38 RECQL NIPBL LDAH SON	1.59e-05	704	91	10	29955894
Pubmed	Differential use of myristoyl groups on neuronal calcium sensor proteins as a determinant of spatio-temporal aspects of Ca2+ signal transduction.	HPCA NCALD	2.03e-05	3	91	2	11836243
Pubmed	Expression of two novel eph-related receptor protein tyrosine kinases in mammary gland development and carcinogenesis.	EPHA2 EPHA5	2.03e-05	3	91	2	8152808
Pubmed	Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy.	SLC14A2 STAT3	2.03e-05	3	91	2	26927669
Pubmed	A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.	RAB8B RAB8A	2.03e-05	3	91	2	12221131
Pubmed	alpha2-macroglobulin- and murinoglobulin-1- deficient mice. A mouse model for acute pancreatitis.	A2M PZP	2.03e-05	3	91	2	10487856
Pubmed	Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice.	EIF2S1 CHAT	2.03e-05	3	91	2	33888613
Pubmed	Over-expression of Eph and ephrin genes in advanced ovarian cancer: ephrin gene expression correlates with shortened survival.	EPHA2 EPHA5	2.03e-05	3	91	2	16737551
Pubmed	Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.	RAB8B RAB8A	2.03e-05	3	91	2	28076793
Pubmed	Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin.	A2M PZP	2.03e-05	3	91	2	12183561
Pubmed	Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer.	RAB8B RAB8A	2.03e-05	3	91	2	31707148
Pubmed	Alpha-2 macroglobulin controls trophoblast positioning in mouse implantation sites.	A2M PZP	2.03e-05	3	91	2	14580373
Pubmed	TMPRSS4 Upregulates TWIST1 Expression through STAT3 Activation to Induce Prostate Cancer Cell Migration.	TMPRSS4 STAT3	2.03e-05	3	91	2	28466252
Pubmed	LincRNA00612 inhibits apoptosis and inflammation in LPS-induced BEAS-2B cells via enhancing interaction between p-STAT3 and A2M promoter.	A2M STAT3	2.03e-05	3	91	2	36883061
Pubmed	Activated human plasma carboxypeptidase B is retained in the blood by binding to alpha2-macroglobulin and pregnancy zone protein.	A2M PZP	2.03e-05	3	91	2	8662763
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	MINDY3 TTC28 NCKAP1 RECQL CPT1A RAB8A DERA	2.41e-05	325	91	7	36168628
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	A2M PNPT1 CS COG1 NUP210L DHX37 VPS13C POLR2B ANAPC7 MTCH2	2.86e-05	754	91	10	35906200
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	HYOU1 NCKAP1 DHX37 EIF4A1 POLR2B NOC4L RECQL CPT1A NIPBL MTCH2 STAT3 RAB8A DERA	3.27e-05	1297	91	13	33545068
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	CS HYOU1 EIF2S1 DHX37 EIF4A1 POLR2B DHX38 NOC4L RECQL NIPBL STAT3 RAB8A SON	3.86e-05	1318	91	13	30463901
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	PNPT1 RAB8B POLR2B NCAPD2 RECQL RAB8A	3.86e-05	237	91	6	29564676
Pubmed	Interaction of matrix metalloproteinases-2 and -9 with pregnancy zone protein and alpha2-macroglobulin.	A2M PZP	4.05e-05	4	91	2	9344465
Pubmed	Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice.	A2M PZP	4.05e-05	4	91	2	27031383
Pubmed	Enhanced plasticity of retinothalamic projections in an ephrin-A2/A5 double mutant.	EPHA2 EPHA5	4.05e-05	4	91	2	11567058
Pubmed	Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.	RAB8B RAB8A	4.05e-05	4	91	2	26471730
Pubmed	The role of interleukin-11 in pregnancy involves up-regulation of alpha2-macroglobulin gene through janus kinase 2-signal transducer and activator of transcription 3 pathway in the decidua.	A2M STAT3	4.05e-05	4	91	2	16959875
Pubmed	Ephrin-A2 and ephrin-A5 guide contralateral targeting but not topographic mapping of ventral cochlear nucleus axons.	EPHA2 EPHA5	4.05e-05	4	91	2	26666565
Pubmed	Regulation of the cell-cycle-dependent internal ribosome entry site of the PITSLRE protein kinase: roles of Unr (upstream of N-ras) protein and phosphorylated translation initiation factor eIF-2alpha.	EIF2S1 CDK11A	4.05e-05	4	91	2	15330758
Pubmed	Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis.	RAB8B RAB8A	4.05e-05	4	91	2	24213529
Pubmed	Central role of the threonine residue within the p+1 loop of receptor tyrosine kinase in STAT3 constitutive phosphorylation in metastatic cancer cells.	STAT3 EPHA5	4.05e-05	4	91	2	15485908
Pubmed	Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors.	A2M PZP	4.05e-05	4	91	2	1702714
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NCKAP1 XIRP2 DHX37 POLR2B NCAPD2 OBSCN CDK11A RECQL	4.95e-05	497	91	8	36774506
Pubmed	Distribution of mRNA coding for alpha-2-macroglobulin, the murinoglobulins, the alpha-2-macroglobulin receptor and the alpha-2-macroglobulin receptor associated protein during mouse embryogenesis and in adult tissues.	A2M PZP	6.74e-05	5	91	2	7514554
Pubmed	The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.	RAB8B RAB8A	6.74e-05	5	91	2	18094055
Pubmed	Neuronal calcium sensor protein visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner.	HPCA HPCAL1	6.74e-05	5	91	2	14739275
Pubmed	Clinical significance of ephrin (eph)-A1, -A2, -a4, -a5 and -a7 receptors in pancreatic ductal adenocarcinoma.	EPHA2 EPHA5	6.74e-05	5	91	2	19949912
Pubmed	Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.	CPT1A STAT3	6.74e-05	5	91	2	34976224
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HPCA NCALD HYOU1 COG1 HPCAL1 RAB8B EIF4A1 NCAPD2 CYB5R3 HKDC1 ANAPC7 NIPBL RAB8A	9.59e-05	1442	91	13	35575683
Pubmed	Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway.	A2M STAT3	1.01e-04	6	91	2	15950906
Pubmed	p97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteins.	EIF2S1 EIF4A1	1.01e-04	6	91	2	16932749
Pubmed	Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity.	EPHA2 EPHA5	1.01e-04	6	91	2	7973638
Pubmed	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	TLN2 GRIN2B	1.01e-04	6	91	2	20197096
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	DHX37 EIF4A1 CYB5R3 VRTN RECQL ANAPC7 SON	1.06e-04	411	91	7	35182466
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PNPT1 EIF2S1 DHX37 EIF4A1 POLR2B CYB5R3 NOC4L PZP NIPBL MTCH2 SON	1.23e-04	1082	91	11	38697112
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	CNOT6L HYOU1 NCKAP1 EIF2S1 DHX37 EIF4A1 POLR2B DHX38 RIOK3 RAB8A SON DERA	1.30e-04	1284	91	12	17353931
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PNPT1 CS HYOU1 TTC28 VPS13C POLR2B CYB5R3 NOC4L PAM16 ANAPC7 MTCH2 RAB8A SON	1.38e-04	1496	91	13	32877691
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CNOT6L NCKAP1 EIF2S1 EIF4A1 POLR2B DHX38 NCAPD2 CDK11A NOC4L ANAPC7 NIPBL MTCH2 SON	1.39e-04	1497	91	13	31527615
Pubmed	HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons.	GRIN2B GRINA	1.41e-04	7	91	2	11606043
Pubmed	Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site.	GRIN2B GRINA	1.41e-04	7	91	2	12775422
Pubmed	Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.	GRIN2B GRINA	1.41e-04	7	91	2	23267846
Pubmed	Tat, a human immunodeficiency virus-1-derived protein, augments excitotoxic hippocampal injury in neonatal rats.	GRIN2B GRINA	1.41e-04	7	91	2	10197777
Pubmed	Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-D-aspartate receptor.	GRIN2B GRINA	1.41e-04	7	91	2	12414113
Pubmed	The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site.	GRIN2B GRINA	1.41e-04	7	91	2	14644469
Pubmed	HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity.	GRIN2B GRINA	1.41e-04	7	91	2	11483648
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	HYOU1 NCKAP1 POLR2B OBSCN HKDC1 STAT3	1.52e-04	304	91	6	32235678
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	HYOU1 NCKAP1 COG1 EIF2S1 EPHA2 EIF4A1 POLR2B NCAPD2 CPT1A MTCH2	1.80e-04	942	91	10	31073040
Pubmed	HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons.	GRIN2B GRINA	1.88e-04	8	91	2	8563977
Pubmed	Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity.	GRIN2B GRINA	1.88e-04	8	91	2	7695237
Pubmed	Human brain N-methyl-D-aspartate receptors regulating noradrenaline release are positively modulated by HIV-1 coat protein gp120.	GRIN2B GRINA	1.88e-04	8	91	2	8724036
Pubmed	The human immunodeficiency virus-1 protein transactivator of transcription up-regulates N-methyl-D-aspartate receptor function by acting at metabotropic glutamate receptor 1 receptors coexisting on human and rat brain noradrenergic neurones.	GRIN2B GRINA	1.88e-04	8	91	2	16489129
Pubmed	Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.	GRIN2B GRINA	1.88e-04	8	91	2	8822372
Pubmed	Glucocorticoid modulation of gp120-induced effects on calcium-dependent degenerative events in primary hippocampal and cortical cultures.	GRIN2B GRINA	1.88e-04	8	91	2	10448428
Pubmed	Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.	GRIN2B GRINA	1.88e-04	8	91	2	8955056
Pubmed	Evidence of HIV type 1 glycoprotein 120 binding to recombinant N-methyl-D-aspartate receptor subunits expressed in a baculovirus system.	GRIN2B GRINA	1.88e-04	8	91	2	10555109
Pubmed	Direct cytotoxicity of HIV-1 envelope protein gp120 on human NT neurons.	GRIN2B GRINA	1.88e-04	8	91	2	8804048
Pubmed	HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism.	GRIN2B GRINA	1.88e-04	8	91	2	9651389
Pubmed	The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid.	GRIN2B GRINA	1.88e-04	8	91	2	8845955
Pubmed	HIV-1 gp120-induced neurotoxicity to midbrain dopamine cultures.	GRIN2B GRINA	1.88e-04	8	91	2	8821747
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	CS NCKAP1 EIF2S1 DHX37 EIF4A1 POLR2B DHX38 NCAPD2 RIOK3 RECQL NIPBL SON	2.12e-04	1353	91	12	29467282
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	A2M CS HYOU1 NCKAP1 EPHA2 RAB8B EIF4A1 NCAPD2 CYB5R3 RECQL MTCH2 SON	2.32e-04	1367	91	12	32687490
Pubmed	GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.	RAB8B RAB8A	2.41e-04	9	91	2	32344433
Pubmed	Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.	EPHA2 EPHA5	2.41e-04	9	91	2	11403717
Pubmed	D1/NMDA receptors and concurrent methamphetamine+ HIV-1 Tat neurotoxicity.	GRIN2B GRINA	2.41e-04	9	91	2	22552781
Pubmed	Targeted inactivation of the mouse alpha 2-macroglobulin gene.	A2M PZP	2.41e-04	9	91	2	7544347
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	HYOU1 NCKAP1 EIF2S1 POLR2B NCAPD2 NOC4L STAT3 SON	2.74e-04	638	91	8	33239621
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	HYOU1 EIF2S1 EIF4A1 NCAPD2 CYB5R3 RECQL MTCH2	2.86e-04	484	91	7	31995728
Pubmed	Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate.	EPHA2 EPHA5	3.01e-04	10	91	2	25073978
Pubmed	The EHEC-host interactome reveals novel targets for the translocated intimin receptor.	NCALD HPCAL1	3.01e-04	10	91	2	25519916
Pubmed	EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes.	EPHA2 EPHA5	3.01e-04	10	91	2	16547242
Pubmed	HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.	EPHA2 EPHA5	3.01e-04	10	91	2	17304517
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS10 ADAMTS6	3.01e-04	10	91	2	11167130
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	A2M ABCA13 EIF4A1 POLR2B NIPBL MTCH2 RAB8A SON	3.17e-04	652	91	8	31180492
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	EIF2S1 EIF4A1 POLR2B DHX38 NCAPD2 RECQL ANAPC7 NIPBL STAT3 SON	3.23e-04	1014	91	10	32416067
Pubmed	An efficient mammalian cell-free translation system supplemented with translation factors.	EIF2S1 EIF4A1	3.67e-04	11	91	2	16289705
Pubmed	Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase.	GRIN2B GRINA	3.67e-04	11	91	2	8581564
Pubmed	An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.	A2M PZP	3.67e-04	11	91	2	19105203
Pubmed	Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice.	EPHA2 EPHA5	3.67e-04	11	91	2	24550361
Pubmed	Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues.	EPHA2 EPHA5	3.67e-04	11	91	2	15517401
Cytoband	12p12	RECQL GRIN2B	2.99e-04	13	91	2	12p12
GeneFamily	Fibronectin type III domain containing	IGSF22 TRIM42 PTPRM EPHA2 OBSCN EPHA5	1.48e-05	160	60	6	555
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS6 ADAMTS18	3.24e-05	19	60	3	50
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	A2M PZP	3.84e-04	9	60	2	1234
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHA2 EPHA5	9.61e-04	14	60	2	1095
GeneFamily	DEAH-box helicases	DHX37 DHX38	1.26e-03	16	60	2	500
GeneFamily	Solute carriers	SLC10A4 SLC19A3 SLC35G2 SLC9C2 SLC14A2 MTCH2	1.94e-03	395	60	6	752
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M XIRP2 GUCY2F ABCA13 OBSCN TLN2 GRIN2B EPHA5	3.91e-09	184	90	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M XIRP2 GUCY2F ABCA13 OBSCN TLN2 GRIN2B EPHA5	3.91e-09	184	90	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M XIRP2 GUCY2F ABCA13 OBSCN TLN2 GRIN2B EPHA5	3.91e-09	184	90	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NCALD TTC28 PTPRM ADAMTS6 OBSCN SEMA3G	2.74e-06	194	90	6	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Artery\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	A2M TTC28 NCKAP1 PTPRM ADAMTS6 SEMA3G	3.27e-06	200	90	6	34b279804475ea58fbb052b96f44128c082627a9
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	A2M TTC28 NCKAP1 PTPRM ADAMTS6 SEMA3G	3.27e-06	200	90	6	8552cc7a439449b30b59760c3e8667217b9852b5
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	A2M TTC28 NCKAP1 PTPRM ADAMTS6 SEMA3G	3.27e-06	200	90	6	45c08f1befe78553bbadcc2fcffb6138306638f3
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M ADAMTS10 ADAMTS6 SERPINB11 PZP	5.56e-06	125	90	5	e112787b05d8147093357c9861877f6620b9e271
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	A2M ADAMTS10 ADAMTS6 SERPINB11 PZP	5.56e-06	125	90	5	34d5be868c9728cc4f9ce0d65acf0e50171d2587
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HPCA ADAMTS18 CHAT GRIN2B ITPRID1	1.63e-05	156	90	5	58b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIAA1549L GUCY2F ABCA13 GRIN2B EPHA5	1.95e-05	162	90	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HPCA ADAMTS18 CHAT GRIN2B ITPRID1	1.95e-05	162	90	5	ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS6 XIRP2 CHAT LCOR	2.32e-05	82	90	4	01a4d47d9e0dee68a5277ed1534338cec80f75d1
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Cadm2_(Cadm2_state)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	ADAMTS6 XIRP2 CHAT LCOR	2.32e-05	82	90	4	c1489097c291f413f3cfa5e26f8182ec872328fd
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STUM NCKAP1 DHX37 SERPINB11 CPT1A	2.75e-05	174	90	5	3f0a5ce074675d57d479fa069385a1b3071e884e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L ADAMTS6 SEMA3G ADGRA2	2.75e-05	174	90	5	3d4c05ea5719ca65e85d1f15198453034791087c
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KIAA1549L TTC28 PTPRM ADAMTS6 SEMA3G	3.15e-05	179	90	5	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA13 ADAMTS18 CHAT GRIN2B ITPRID1	3.69e-05	185	90	5	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	A2M NCALD CNOT6L RABGAP1L PZP	3.69e-05	185	90	5	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KLHL1 KIAA1549L ADAMTS6 TLN2 GRIN2B	3.78e-05	186	90	5	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	A2M CNOT6L PTPRM ADAMTS6 SEMA3G	3.88e-05	187	90	5	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L PTPRM ADAMTS6 SEMA3G	4.08e-05	189	90	5	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L TTC28 ADAMTS6 SEMA3G	4.08e-05	189	90	5	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M ADAMTS6 NUP210L SEMA3G ADGRA2	4.19e-05	190	90	5	d0297d678498e346e56cf95fe9e3db7d3ad3b837
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M TTC28 PTPRM ADAMTS6 SEMA3G	4.40e-05	192	90	5	28eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L PTPRM ADAMTS6 SEMA3G	4.51e-05	193	90	5	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L PTPRM ADAMTS6 SEMA3G	4.51e-05	193	90	5	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	A2M TTC28 PTPRM ADAMTS6 SEMA3G	4.62e-05	194	90	5	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L PTPRM ADAMTS6 SEMA3G	4.62e-05	194	90	5	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	3'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M PTPRM HPCAL1 SLC35G2 SEMA3G	4.74e-05	195	90	5	d46955155e5b22d00939eaf5edfb8ac217d06e46
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L PTPRM ADAMTS6 SEMA3G	4.74e-05	195	90	5	77e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M TTC28 PTPRM ADAMTS6 SEMA3G	4.85e-05	196	90	5	cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M TTC28 PTPRM ADAMTS6 SEMA3G	5.09e-05	198	90	5	b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT2 GPC3 NCKAP1 POLR2B SON	5.09e-05	198	90	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT2 GPC3 NCKAP1 POLR2B SON	5.09e-05	198	90	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	A2M PTPRM ADAMTS6 SLC35G2 SEMA3G	5.22e-05	199	90	5	bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	A2M TTC28 PTPRM ADAMTS6 SEMA3G	5.22e-05	199	90	5	9735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	A2M TTC28 PTPRM ADAMTS6 SEMA3G	5.22e-05	199	90	5	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	A2M TTC28 PTPRM ADAMTS6 SEMA3G	5.34e-05	200	90	5	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 EPHA2 SERPINB11 OBSCN TMPRSS4	5.34e-05	200	90	5	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	VPS13C RIOK3 NIPBL STAT3 SON	5.34e-05	200	90	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Deptor_(Deep_layer_pyramidal_cells--Layer_5a)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	STUM ADAMTS18 HKDC1 ITPRID1	6.84e-05	108	90	4	514dfc3f7ac303311ae599f981f3f3c7eb6801b8
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_B2-7\|TCGA-Thymus / Sample_Type by Project: Shred V9	ENO4 GALT GUCY2F ADAMTS18	9.03e-05	116	90	4	de4c3700e6b2f79583f74262df2380714ce9cd6b
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY2F TLN2 ITPRID1 EPHA5	2.08e-04	144	90	4	1d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY2F TLN2 ITPRID1 EPHA5	2.08e-04	144	90	4	d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY2F ABCA13 GRIN2B EPHA5	2.13e-04	145	90	4	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Adult-Immune-enucleated_erythrocyte-D175\|Adult / Lineage, Cell type, age group and donor	VRTN TMPRSS4 NOC4L PZP	2.55e-04	152	90	4	530d5427d8617dcb223d807b73abee0ef89285f3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L ADAMTS6 SEMA3G	2.68e-04	154	90	4	e51a5114f0ec38f997f5b8bbf3a7770f98595474
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TRPA1 SLC10A4 CHAT	2.69e-04	62	90	3	3eec7f31de7cc24762c5b180475650676437dc76
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TRPA1 SLC10A4 CHAT	2.69e-04	62	90	3	f5f5441f5be00ab80a7827c4af1afbe45c552c2e
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TRPA1 SLC10A4 CHAT	2.69e-04	62	90	3	6e81a37b9defa96528654bee1b23152108d9c0b7
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	KLHL1 XIRP2 NUP210L EPHA5	3.03e-04	159	90	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	XIRP2 ABCA13 SERPINB11 TMPRSS4	3.03e-04	159	90	4	60b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VRTN CHAT GRIN2B ITPRID1	3.18e-04	161	90	4	f5df8c6a340d5026726804b103e32137f363ca40
ToppCell	Club_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS10 ABCA13 TMPRSS4 ITPRID1	3.18e-04	161	90	4	bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M TRPA1 EIF5A2 ARHGEF25	3.25e-04	162	90	4	68c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	A2M TRPA1 EIF5A2 ARHGEF25	3.25e-04	162	90	4	735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	A2M ADAMTS6 SEMA3G ADGRA2	3.33e-04	163	90	4	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA1549L ADAMTS6 GRIN2B SEMA3G	3.41e-04	164	90	4	3cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	KLHL1 ADAMTS6 XIRP2 SLC10A4	3.57e-04	166	90	4	6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VRTN CHAT GRIN2B ITPRID1	3.73e-04	168	90	4	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	356C-Fibroblasts-Fibroblast-H-\|356C / Donor, Lineage, Cell class and subclass (all cells)	A2M STUM GPC3 ARHGEF25	3.73e-04	168	90	4	b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell	356C-Fibroblasts-Fibroblast-H\|356C / Donor, Lineage, Cell class and subclass (all cells)	A2M STUM GPC3 ARHGEF25	3.73e-04	168	90	4	838ce47d4958ba12047882f97925eddd02f081c7
ToppCell	NS-critical-d_0-4-Myeloid-Monocyte-derived_DC\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	A2M EIF4A1 TLN2 SLC14A2	3.82e-04	169	90	4	6fe82db874eff0f86e5c0d1cc81322eb9d7874eb
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|Monocyte / Lineage, cell class and subclass	RAB8B RIOK3 LCOR AQP9	3.82e-04	169	90	4	7c3144a6599787f28662f5b22b8e45f4a115aeda
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS18 CHAT GRIN2B ITPRID1	3.82e-04	169	90	4	05e12524d68d409fed386ffad233305683b4575b
ToppCell	Ionocyte-iono-1\|World / Class top	NCALD TLN2 PZP EPHA5	3.82e-04	169	90	4	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPC3 SLC10A4 ARHGEF25 ADGRA2	3.82e-04	169	90	4	6ff1172da690ca17f7108f1617b255b766971a57
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL1 SLC19A3 CHAT ITPRID1	3.90e-04	170	90	4	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	HPCAL1 RAB8B GRINA AQP9	4.08e-04	172	90	4	965a9f62b73a7e3531c343121a7c507b7e1bfe05
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	A2M ABCA13 CHAT EPHA5	4.08e-04	172	90	4	d354424c1f861b6607dfd63b9724f4c237b30275
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D VPS13C TMPRSS4 CHAT	4.26e-04	174	90	4	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	A2M PTPRM ADAMTS6 SEMA3G	4.26e-04	174	90	4	18ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA2 P2RY10 HKDC1 EMC9	4.45e-04	176	90	4	3c3b6c02d7acdc1305878ee34e9cbabbf9e87892
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA2 P2RY10 HKDC1 EMC9	4.45e-04	176	90	4	7c743b7e954c1ebfa289ed529abacb88504112ea
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SLC10A4 CHAT SEMA3G EPHA5	4.54e-04	177	90	4	8c78f7de091f16e86e326a73c9f1429e0232821f
ToppCell	PCW_13-14-Neuronal-Neuronal_SCP\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KLHL1 GRIN2B SEMA3G EPHA5	4.54e-04	177	90	4	621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-basal_proximal\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TRPA1 EPHA2 ADAMTS18 TMPRSS4	4.64e-04	178	90	4	9534c4f4e950bb1498c1737ca1713e7f37d0aff2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	A2M KIAA1549L ADAMTS6 SEMA3G	4.64e-04	178	90	4	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA13 EPHA2 SERPINB11 TMPRSS4	4.74e-04	179	90	4	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS18 CHAT GRIN2B ITPRID1	4.74e-04	179	90	4	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MINDY3 HYOU1 PTPRM NCAPD2	4.74e-04	179	90	4	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	A2M PTPRM ADAMTS6 SEMA3G	4.74e-04	179	90	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	MatrixFB-Fibroblast-A\|MatrixFB / shred on cell class and cell subclass (v4)	CACNA1D GPC3 VPS13C SON	4.84e-04	180	90	4	adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPC3 SLC10A4 ARHGEF25 ADGRA2	4.94e-04	181	90	4	6d1f1ad35778a2a227f966f11f6edd8e89452576
ToppCell	RV\|World / Chamber and Cluster_Paper	PTPRM XIRP2 OBSCN TLN2	4.94e-04	181	90	4	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M PTPRM SEMA3G PZP	5.05e-04	182	90	4	0639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage-immature_B_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS6 POLR2B P2RY10 SON	5.05e-04	182	90	4	ab78df9de3878a6d67106a40094c893601de8076
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 ADAMTS6 NCAPD2 DEPDC1	5.05e-04	182	90	4	3948422707d6d5e021bcd7158e2eb69143613f62
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ENO4 ADAMTS6 NCAPD2 DEPDC1	5.05e-04	182	90	4	fe46819c153a81911864473badc794f243705f98
ToppCell	3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	A2M TTC28 SEMA3G PZP	5.26e-04	184	90	4	842473fa415575441b595073a994b6d621169776
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	PTPRM XIRP2 RABGAP1L OBSCN	5.26e-04	184	90	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4-_Ptgds_(Bmp4)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GUCY2F MROH2B CA6	5.28e-04	78	90	3	87ed71a692416a21c8c11b5adbfe629f7d57ddb4
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Bmp4-_Ptgds_(Bmp4)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	GUCY2F MROH2B CA6	5.28e-04	78	90	3	9545ae56fda3893b82b5efa82082e1f585a5f92a
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NCALD HPCAL1 RAB8B AQP9	5.37e-04	185	90	4	42690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	PTPRM XIRP2 RABGAP1L OBSCN	5.37e-04	185	90	4	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	NCALD CNOT6L RABGAP1L PZP	5.37e-04	185	90	4	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	COPD-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	ABCA13 EPHA2 SERPINB11 TMPRSS4	5.48e-04	186	90	4	d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	GPC3 TTC28 TLN2 CA6	5.48e-04	186	90	4	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	GPC3 TTC28 TLN2 CA6	5.48e-04	186	90	4	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
Drug	Reidispongiolide C	GUCY2F EPHA2 CYB5R3 CHAT GRIN2B GRINA AQP9 STAT3 EPHA5	1.63e-06	279	90	9	CID005289285
Disease	Alzheimer's disease (is_implicated_in)	A2M EIF2S1 CHAT GRIN2B STAT3	4.83e-05	132	88	5	DOID:10652 (is_implicated_in)
Disease	Dyggve-Melchior-Clausen disease (implicated_via_orthology)	RAB8B RAB8A	5.26e-05	4	88	2	DOID:0111167 (implicated_via_orthology)
Disease	Smith-McCort dysplasia (implicated_via_orthology)	RAB8B RAB8A	8.74e-05	5	88	2	DOID:0060247 (implicated_via_orthology)
Disease	Squamous cell carcinoma of lung	GUCY2F EPHA2 EPHA5	1.19e-04	32	88	3	C0149782
Disease	DNA methylation	CNOT6L PTPRM ADAMTS6 ABCA13 MROH2B RABGAP1L ADAMTS18 GRIN2B CA6	1.50e-04	656	88	9	GO_0006306
Disease	refractive error, age at onset, Myopia	CACNA1D PNPT1 GRIN2B PZP SLC14A2	2.87e-04	193	88	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	serum metabolite measurement	KLHL1 TRPA1 RAB8B RABGAP1L DHX38 CYB5R3 TLN2 CPT1A MTCH2 STAT3	5.11e-04	945	88	10	EFO_0005653
Disease	lymphangioleiomyomatosis (is_marker_for)	CPT1A STAT3	5.69e-04	12	88	2	DOID:3319 (is_marker_for)
Disease	stenosing tenosynovitis	KLHL1 ADAMTS6	5.69e-04	12	88	2	EFO_0010822
Disease	body weights and measures, body height	ADAMTS10 RIOK3	9.00e-04	15	88	2	EFO_0004324, EFO_0004339
Disease	response to selective serotonin reuptake inhibitor	TMPRSS4 NOC4L GRIN2B	1.91e-03	82	88	3	EFO_0005658
Disease	prostate specific antigen measurement	A2M GPC3 ADAMTS18 LDAH	2.45e-03	188	88	4	EFO_0004624
Disease	blood chromium measurement	KIAA1549L PTPRM	2.73e-03	26	88	2	EFO_0007579
Disease	pulse pressure measurement	CACNA1D PNPT1 KIAA1549L TTC28 NCKAP1 TLN2 ARHGEF25 SLC14A2 MTCH2 LDAH STAT3	2.83e-03	1392	88	11	EFO_0005763
Disease	glucose tolerance test	VPS13C HKDC1	2.94e-03	27	88	2	EFO_0004307
Disease	refractive error	A2M CACNA1D PNPT1 GRIN2B SLC14A2	2.96e-03	326	88	5	MONDO_0004892

Protein segments in the cluster

Peptide	Gene	Start	Entry
NVGFSMAVAMAIYVA	AQP9	61	O43315
TYTSKHSVEVQVNMM	ACOT7L	51	Q6ZUV0
QIVEGYMATMAAQGV	ARHGEF25	181	Q86VW2
MDVVYVAQMIQKFLG	ADGRA2	461	Q96PE1
SKPVMIVTEYMENGS	EPHA5	746	P54756
VVGVMTTMYAKIDPS	CPT1A	66	P50416
MVSVASMVRKLVYEQ	ABCA13	3581	Q86UQ4
RMTVADGTVYIAQQM	CA6	96	P23280
VETLVVADKMMVAYH	ADAMTS10	241	Q9H324
KGNVTTYILTVMNMV	ADAMTS18	311	Q8TE60
FVETLVVADKMMVGY	ADAMTS6	251	Q9UKP5
SNMAIVDVKMVSGFI	A2M	1376	P01023
GVSTMNEMKSYSQAV	MTCH2	211	Q9Y6C9
ASNMVIVDVKMVSGF	PZP	1381	P20742
KMSQYLESMQIGDTI	CYB5R3	126	P00387
AMGIMLVYDITNEKS	RAB8A	81	P61006
AMGIMLVYDITNEKS	RAB8B	81	Q92930
MLEIVQAIYKMVSSV	HPCA	121	P84074
DTSYGTVKAENIIMM	SLC10A4	416	Q96EP9
EAMVMANNVYKTLGA	ANAPC7	391	Q9UJX3
KVMYVEGTAVVMGFE	MINDY3	396	Q9H8M7
AGMQKIITLVYTAMT	OR11H6	286	Q8NGC7
MVGMIASFYNTEAVI	GRINA	241	Q7Z429
VSLYEQGMVQMTVKD	ITPRID1	86	Q6ZRS4
VMQGCMAGVVEIDKY	GPC3	281	P51654
MVNVRSIAEMGAYVS	EIF2S1	21	P05198
SVMCAMSEEYAVAIK	EIF5A2	136	Q9GZV4
IQKVVMALGDYMGAS	EIF4A1	116	P60842
VMSGKMSVSKAQSIY	LCOR	361	Q96JN0
DMKANSIYGMFVIVS	OR51G2	196	Q8NGK0
MLEIVQAIYKMVSSV	HPCAL1	121	P37235
KAVAGMKMSYQVQQA	NIPBL	2356	Q6KC79
IMYNMANTSKRGVVI	DEPDC1	221	Q5TB30
TLGSYTVQMVKMQRV	KIAA1549L	1106	Q6ZVL6
MGTDKMASVFYAIVI	OR5B12	266	Q96R08
FTKSIVGMTMYNQAT	NCKAP1	716	Q9Y2A7
VGMTMYNQATQEIAK	NCKAP1	721	Q9Y2A7
DKQVYMTVAVDMVVT	RABGAP1L	386	Q5R372
KYDVVCEGTMAMLVI	OBSCN	2871	Q5VST9
TIVTYQMVKTKEAGM	HYOU1	241	Q9Y4L1
VKQMGTKYMLVISNV	IGSF22	286	Q8N9C0
EMLKSCMVQVVAAYE	COG1	771	Q8WTW3
TVRKFMVGYEMLAQA	GALT	331	P07902
MAAGYTAIEKVVQMT	EPHA2	926	P29317
GKTVVGQITVDMMYG	CS	56	O75390
GDVYSFAIIMQEVMV	GUCY2F	731	P51841
IVVGSNMDKIYIVMN	CDK11A	491	Q9UQ88
EVIMGTYKNAAEMVD	ENO4	411	A6NNW6
MGEVEISALAYVKMC	EMC9	1	Q9Y3B6
LGTLTNVYKASMIAM	DERA	196	Q9Y315
VYQEIVETTKMYMKG	DHX37	981	Q8IY37
QGVKTMQVVEFFYGM	SLC19A3	101	Q9BZV2
MVMTGSQGATRKYKV	NOC4L	76	Q9BVI4
MLEIVQAIYKMVSSV	NCALD	121	P61601
NMVFTGVFTVEMVLK	CACNA1D	1241	Q01668
GYKQMNAVALVGMIT	P2RY10	186	O00398
ATKMPVYVMGVTSTQ	NUP210L	1186	Q5VU65
VMVNSMDKSYAEQGT	PTPRM	786	P28827
HNTVKDTVMAVMYTG	OR1E3	266	Q8WZA6
KYVYVTTMKVNEMDG	TRIM42	411	Q8IWZ5
VAFIGMYQTMTKKAA	SIDT2	216	Q8NBJ9
EKMTSGMYLGEIVRQ	HKDC1	741	Q2TB90
EKMAYVDMATVVCSI	SLC35G2	216	Q8TBE7
SAMGKQAMGVYITNF	POLR2B	726	P30876
EGKNVTVEMMYQIGT	SERPINB11	206	Q96P15
VACAMYEVISMGTSV	MROH2B	1141	Q7Z745
DTGVMVKLYPNMTAV	PNPT1	691	Q8TCS8
AQTAYTVMAITGMAI	CHAT	606	P28329
EAIGIISKMMYENTT	NCAPD2	636	Q15021
ISKMMYENTTTVVQE	NCAPD2	641	Q15021
EYSDVKLIQTMMFVS	CNOT6L	366	Q96LI5
VMENVGQQKLYEMVS	RECQL	431	P46063
MYKMVNSGMLETITG	RIOK3	241	O14730
YENIIQTAMMSSKTG	XIRP2	2851	A4UGR9
ASMGGYTQTMKVILD	TRPA1	521	O75762
MDMVILAISQGYKEQ	STUM	121	Q69YW2
AEIIMGYKIMDATNI	STAT3	651	P40763
NMVTGYISIDAMKKF	TERB2	171	Q8NHR7
AYQGEVTEKMMCAGI	TMPRSS4	361	Q9NRS4
NMEYLVGVSIKMSSF	VPS13C	2846	Q709C8
ELVMTTKEYMQCVTA	DHX38	1121	Q92620
YIGTKSMAALTVMAA	RFX7	156	Q2KHR2
MAKYLAQIIVMGVQV	PAM16	1	Q9Y3D7
SLEAQVYGNMGITKM	TTC28	831	Q96AY4
SMYQLKGAAKVMVTN	TLN2	2111	Q9Y4G6
NMTMKFVIIVYGSVI	SLC9C2	1041	Q5TAH2
EMEISVKRQMLYVGS	SEMA3G	496	Q9NS98
QGMIDSKVMLQAVRY	VRTN	121	Q9H8Y1
YMEAAISNIMSVVGV	SLC14A2	381	Q15849
EPVVTMSVEYQMKSV	SON	261	P18583
MYGEQILSVVAMSQL	TMEM14EP	106	Q6UXP3
KVAHSYTMENIMEVI	KLHL1	331	Q9NR64
NAAYLGGQEMMEVVK	LDAH	236	Q9H6V9
VVMKRAYMAVGSLTI	GRIN2B	501	Q13224