Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	CELSR2 PTPRG CDHR2 FAT3 CDH23 PLXNB2 PCDHGA8	1.43e-05	187	87	7	GO:0007156
Domain	IQ	MYO1C MYO5A SCN2A SPA17 PPEF2	4.96e-05	81	92	5	SM00015
Domain	P-loop_NTPase	ABCB7 SAMD9 MYO1C MYO5A DDX60 NDST4 HS3ST5 RNF213 DLG2 UCK1 ATL2 DNAH5 DDX1 CASK	6.63e-05	848	92	14	IPR027417
Domain	IQ_motif_EF-hand-BS	MYO1C MYO5A SCN2A SPA17 PPEF2	8.21e-05	90	92	5	IPR000048
Domain	IQ	MYO1C MYO5A SCN2A SPA17 PPEF2	9.60e-05	93	92	5	PS50096
Domain	Cadherin_CS	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.03e-04	109	92	5	IPR020894
Domain	CADHERIN_1	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.40e-04	113	92	5	PS00232
Domain	Cadherin	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.40e-04	113	92	5	PF00028
Domain	CADHERIN_2	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.50e-04	114	92	5	PS50268
Domain	-	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.50e-04	114	92	5	2.60.40.60
Domain	CA	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.60e-04	115	92	5	SM00112
Domain	Cadherin-like	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.71e-04	116	92	5	IPR015919
Domain	-	ABCB7 SAMD9 DDX60 NDST4 HS3ST5 RNF213 DLG2 UCK1 ATL2 DNAH5 DDX1 CASK	2.92e-04	746	92	12	3.40.50.300
Domain	Cadherin	CELSR2 CDHR2 FAT3 CDH23 PCDHGA8	2.93e-04	118	92	5	IPR002126
Domain	IQ	MYO1C MYO5A SPA17 PPEF2	4.16e-04	71	92	4	PF00612
Domain	ConA-like_dom	RFPL4B THBS4 CELSR2 FAT3 FSD2 DDX1	7.48e-04	219	92	6	IPR013320
Domain	Rap_GAP	RAP1GAP2 TSC2	1.05e-03	10	92	2	PF02145
Domain	Rap_GAP_dom	RAP1GAP2 TSC2	1.28e-03	11	92	2	IPR000331
Domain	RAPGAP	RAP1GAP2 TSC2	1.28e-03	11	92	2	PS50085
Domain	Spy1	SPDYE21 SPDYE5	1.28e-03	11	92	2	PF11357
Domain	Speedy	SPDYE21 SPDYE5	1.28e-03	11	92	2	IPR020984
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	THBS4 NAMPT SERPINI2 PTPRG MYO1C RNPEP MYO5A CDHR2 NPEPPS PABPC1L2A ACP2 C9 IDUA ALDOC SERPINA5 CNTN1	2.03e-08	1070	92	16	23533145
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ABCB7 NAMPT WAPL MYO1C NRDC RNPEP NPEPPS ASNS PRPF6 TUBGCP2 CASK PTCD3	3.04e-08	560	92	12	35241646
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	NAMPT NRDC MORN1 CSN2 CPSF6 GYS1 ASNS RCN1 PRPF6 DDX1 PTCD3	1.28e-06	653	92	11	33742100
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	PMS2 WAPL CPSF6 RNF213 TSC2 PRPF6 TUBGCP2 TRRAP	3.58e-06	341	92	8	32971831
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	ADCY4 NAMPT WAPL MYO1C NRDC RNPEP CPSF6 NPEPPS ASNS PRPF6 ATL2 ALDOC DNAH5 DDX1 PTCD3	4.83e-06	1425	92	15	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ADCY4 THBS4 MYO1C NRDC RNPEP MYO5A NPEPPS SCN2A DPYSL4 DLG2 ALDOC DDX1 CNTN1 CASK PTCD3	5.08e-06	1431	92	15	37142655
Pubmed	Miniglucagon (MG)-generating endopeptidase, which processes glucagon into MG, is composed of N-arginine dibasic convertase and aminopeptidase B.	NRDC RNPEP	6.92e-06	2	92	2	15539558
Pubmed	A myosin family tree.	MYO5A CDH23	6.92e-06	2	92	2	10984423
Pubmed	CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.	ABCB7 RNF213 TSC2 TUBGCP2 TRRAP	8.68e-06	104	92	5	31240132
Pubmed	Stereociliary myosin-1c receptors are sensitive to calcium chelation and absent from cadherin 23 mutant mice.	MYO1C CDH23	2.07e-05	3	92	2	17050716
Pubmed	Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73.	THBS4 PTPRG	2.07e-05	3	92	2	15897551
Pubmed	Altered Activity and Expression of Cytosolic Peptidases in Colorectal Cancer.	RNPEP NPEPPS	2.07e-05	3	92	2	26078706
Pubmed	Spatial and temporal expression of lysosomal acid phosphatase 2 (ACP2) reveals dynamic patterning of the mouse cerebellar cortex.	ACP2 ALDOC	2.07e-05	3	92	2	23780826
Pubmed	Sperm Proteome Analysis and Identification of Fertility-Associated Biomarkers in Unexplained Male Infertility.	SPA17 SERPINA5	2.07e-05	3	92	2	31336797
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	ZNF12 ABCB7 MYO1C RNPEP MYO5A CPSF6 TSC2 DPP3 TUBGCP2 PLXNB2 CASK	3.36e-05	925	92	11	28986522
Pubmed	ANXA2, SP17, SERPINA5, PRDX2 genes, and sperm DNA fragmentation differentially represented in male partners of infertile couples with normal and abnormal sperm parameters.	SPA17 SERPINA5	4.14e-05	4	92	2	36177795
Pubmed	Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.	WAPL RNF213	4.14e-05	4	92	2	18187866
Pubmed	The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.	PTPRG CNTN1	4.14e-05	4	92	2	20133774
Pubmed	Defining the membrane proteome of NK cells.	NPC1 MYO1C MYO5A CPSF6 ACP2 GYS1 RNF213 PRPF6 TUBGCP2 ATL2 ITGAX DDX1	5.95e-05	1168	92	12	19946888
Pubmed	Cell-based receptor discovery identifies host factors specifically targeted by the SARS CoV-2 spike.	IL1RAPL2 CNTN1	6.89e-05	5	92	2	35931765
Pubmed	LDL-cholesterol concentrations: a genome-wide association study.	TDRD15 CELSR2	6.89e-05	5	92	2	18262040
Pubmed	A genome-wide association study identifies susceptibility loci for Wilms tumor.	DLG2 DDX1	1.03e-04	6	92	2	22544364
Pubmed	A genome-wide association study identifies susceptibility loci of silica-related pneumoconiosis in Han Chinese.	CPSF6 CNTN1	1.03e-04	6	92	2	24986923
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ABCB7 NAMPT MYO1C NPEPPS DDX60 ASNS RCN1 RNF213 TSC2 PRPF6 TUBGCP2 DDX1 PTCD3	1.06e-04	1440	92	13	30833792
Pubmed	Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.	WAPL MYO1C CPSF6 PRPF6 DDX1	1.26e-04	182	92	5	32239614
Pubmed	A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.	DLG2 CASK	1.44e-04	7	92	2	9753324
Pubmed	Zebrin II Is Ectopically Expressed in Microglia in the Cerebellum of Neurogenin 2 Null Mice.	ACP2 ALDOC	1.44e-04	7	92	2	29909450
Pubmed	Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.	MYO5A CDH23	1.44e-04	7	92	2	15572405
Pubmed	Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein.	MYO5A DLG2	1.44e-04	7	92	2	10844022
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	NAMPT WAPL TSC2 PRPF6 TUBGCP2 TRRAP	1.50e-04	300	92	6	28561026
Pubmed	The DNA sequence of human chromosome 7.	PMS2 NAMPT SAMD9 ASNS SPDYE21 SPDYE5 TRRAP	1.74e-04	441	92	7	12853948
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TYK2 IFT140 WAPL MYO1C FAT3 RCN1 RNF213 TUBGCP2 TAF5 TRRAP PTCD3	1.77e-04	1116	92	11	31753913
Pubmed	Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97.	DLG2 CASK	1.92e-04	8	92	2	12351654
Pubmed	Temporal and spatial expression profiles of the Fat3 protein, a giant cadherin molecule, during mouse development.	FAT3 CNTN1	1.92e-04	8	92	2	17131403
Pubmed	The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.	MYO1C RNPEP DPP3 ALDOC DDX1	2.10e-04	203	92	5	35012549
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	RNPEP MYO5A CPSF6 NPEPPS GYS1 ASNS RCN1 PRPF6 ALDOC DDX1 PTCD3	2.28e-04	1149	92	11	35446349
Pubmed	Identification of FBXO25-interacting proteins using an integrated proteomics approach.	FBXO25 MYO1C MYO5A NPEPPS	2.29e-04	112	92	4	20473970
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CELSR2 MYO5A NPEPPS DPYSL4 CDK5RAP2 DLG2 TSC2 TAF5 CNTN1 CASK	2.35e-04	963	92	10	28671696
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	MYO1C DDX60 RNF213 CDK5RAP2 DNAH5	2.35e-04	208	92	5	33230847
Pubmed	TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.	TAF5 TRRAP	2.46e-04	9	92	2	15899866
Pubmed	Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.	MYO1C CDH23	2.46e-04	9	92	2	19339464
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	WAPL GYS1 ASNS RNF213 PRPF6 DDX1	2.59e-04	332	92	6	32786267
Pubmed	Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis.	CPSF6 PABPC1L2A GYS1 PTCD3	2.71e-04	117	92	4	34662580
Pubmed	The nuclear import of TAF10 is regulated by one of its three histone fold domain-containing interaction partners.	TAF5 TRRAP	3.07e-04	10	92	2	15870280
Pubmed	CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex.	CDK5RAP2 TUBGCP2	3.07e-04	10	92	2	21135143
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	MYO1C NRDC USP42 NPEPPS GYS1 PRPF6 DPP3 TUBGCP2 TRRAP CASK	3.29e-04	1005	92	10	19615732
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYO1C RNPEP MYO5A NPEPPS ASNS PRPF6 TRRAP PTCD3	3.45e-04	653	92	8	22586326
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	NPC1 MYO1C RNPEP CDHR2 NPEPPS ACP2 CDK5RAP2 C9 ALDOC SERPINA5	3.58e-04	1016	92	10	19056867
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	MYO1C MYO5A DDX60 TUBGCP2 PTCD3	3.59e-04	228	92	5	30471916
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	WAPL CPSF6 NPEPPS BEND4 PRPF6 MYOM2 TRRAP	3.59e-04	497	92	7	36774506
Pubmed	High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1.	SIAH1 CASK	3.75e-04	11	92	2	19523119
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	NAMPT MYO1C DDX60 ASNS RCN1	4.12e-04	235	92	5	28378594
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PMS2 PTPRG MYO1C MYO5A PPM1E RCN1 RNF213 CDK5RAP2 PPEF2 CASK	4.60e-04	1049	92	10	27880917
Pubmed	SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors.	TAF5 TRRAP	5.30e-04	13	92	2	23884650
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	USP42 CPSF6 GYS1 DPYSL4 SIAH1 PRPF6 TRRAP DDX1 CASK PTCD3	5.85e-04	1082	92	10	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NPC1 PMS2 ABCB7 WAPL NRDC CPSF6 UBP1 CDK5RAP2 G2E3 ZMAT1	5.93e-04	1084	92	10	11544199
Pubmed	Identification of a small TAF complex and its role in the assembly of TAF-containing complexes.	TAF5 TRRAP	6.17e-04	14	92	2	17375202
Pubmed	Targeting TRIM3 deletion-induced tumor-associated lymphangiogenesis prohibits lymphatic metastasis in esophageal squamous cell carcinoma.	MYO5A PRPF6	6.17e-04	14	92	2	30542119
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	MYO1C USP42 CPSF6 DENND2C PRPF6 DDX1 CASK PTCD3	6.74e-04	723	92	8	34133714
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 TYK2 CELSR2 MORN1 RAP1GAP2 TSC2 IDUA PLXNB2 TRRAP TPCN1	6.88e-04	1105	92	10	35748872
Pubmed	The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules.	MYO1C GYS1 DDX1	6.95e-04	65	92	3	32521226
Pubmed	Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis.	TAF5 TRRAP	7.11e-04	15	92	2	12601814
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	CELSR2 NPEPPS FAT3	7.59e-04	67	92	3	21875946
Pubmed	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.	TYK2 NAMPT MYO1C NPEPPS DPP3 ALDOC PLXNB2	7.66e-04	565	92	7	20458337
Pubmed	Repression of rRNA transcription by PARIS contributes to Parkinson's disease.	MYO1C NPEPPS PRPF6 TUBGCP2 PTCD3	7.97e-04	272	92	5	25315684
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY4 CDH23	8.11e-04	16	92	2	17567809
Pubmed	Beta-catenin interacts with the FUS proto-oncogene product and regulates pre-mRNA splicing.	PRPF6 DDX1	8.11e-04	16	92	2	16230076
Pubmed	A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro.	UBP1 TAF5	8.11e-04	16	92	2	7836461
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	TYK2 NAMPT NPEPPS TSC2 CASK	8.50e-04	276	92	5	28319085
Pubmed	Histone-like TAFs within the PCAF histone acetylase complex.	TAF5 TRRAP	9.17e-04	17	92	2	9674425
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	NPC1 NAMPT MYO1C CPSF6 NPEPPS ASNS DPYSL4 RNF213 PRPF6 ATL2 PLXNB2	9.68e-04	1367	92	11	32687490
Pubmed	Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.	NAMPT CPSF6 NPEPPS ALDOC	1.01e-03	166	92	4	27160897
Pubmed	Comprehensive Proteomic Analysis of PGC7-Interacting Proteins.	SIAH1 PRPF6 TUBGCP2 DDX1 PTCD3	1.01e-03	287	92	5	28712289
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TDRD15 MYO1C CPSF6 RNF213 CDK5RAP2 ZMAT1 CASK PTCD3	1.07e-03	777	92	8	35844135
Pubmed	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	CELSR2 RNF213	1.15e-03	19	92	2	23118302
Pubmed	Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.	DLG2 CASK	1.15e-03	19	92	2	15024025
Pubmed	Gene Expression by Mouse Inner Ear Hair Cells during Development.	CDH23 DNAH5	1.15e-03	19	92	2	25904789
Pubmed	Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.	NAMPT GYS1 TSC2 PRPF6	1.20e-03	174	92	4	29669786
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	WAPL MYO1C USP42 CPSF6 RCN1 PRPF6 ATL2 DDX1 PTCD3	1.24e-03	989	92	9	36424410
Pubmed	UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation.	TAF5 TRRAP	1.27e-03	20	92	2	11406595
Pubmed	Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II.	TAF5 TRRAP	1.27e-03	20	92	2	9603525
Pubmed	Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.	TAF5 TRRAP	1.27e-03	20	92	2	10373431
Pubmed	Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development.	GYS1 ALDOC	1.27e-03	20	92	2	39040069
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	RCN1 RNF213 PRPF6 ALDOC DDX1	1.31e-03	304	92	5	32235678
Pubmed	Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation.	CEACAM3 NDST4 HS3ST5	1.32e-03	81	92	3	39217171
Pubmed	In silico QTL mapping of basal liver iron levels in inbred mouse strains.	PMS2 SIAH1	1.41e-03	21	92	2	21062905
Pubmed	Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins.	WAPL CPSF6 CASK	1.46e-03	84	92	3	34159380
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	MYO5A TSC2 TUBGCP2 PLXNB2 CNTN1	1.48e-03	313	92	5	38270169
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	HECTD2 RNF213 SIAH1	1.51e-03	85	92	3	19028597
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	ABCB7 CELSR2 MYO1C CPSF6 ACP2 RNF213 PRPF6 ATL2 PLXNB2 DDX1 PTCD3	1.56e-03	1451	92	11	30550785
Pubmed	Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.	DLG2 CASK	1.69e-03	23	92	2	16637659
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	CPSF6 DDX1 PTCD3	1.73e-03	89	92	3	22446626
Pubmed	LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.	MYO1C MYO5A NPEPPS RCN1 ALDOC	1.80e-03	327	92	5	31409639
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	SAMD9 MYO1C MYO5A CPSF6 DDX60 PRPF6 TUBGCP2 C9 DDX1 PTCD3	1.81e-03	1257	92	10	36526897
Pubmed	Identification of a large set of rare complete human knockouts.	GUCA1C PCDHGA8	1.84e-03	24	92	2	25807282
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TYK2 KBTBD3 PTPRG MORN1 MYO5A NPEPPS RNF213 G2E3 TRRAP ZMAT1 CASK	1.91e-03	1489	92	11	28611215
Pubmed	Leber Congenital Amaurosis / Early-Onset Severe Retinal Dystrophy Overview	RPGRIP1 IFT140	2.00e-03	25	92	2	30285347
Pubmed	SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.	DLG2 CASK	2.00e-03	25	92	2	27480238
Pubmed	Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.	IFT140 DNAH5	2.00e-03	25	92	2	27340223
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NPC1 PMS2 WAPL MYO5A HECTD2 RAP1GAP2 DLG2 SIAH1 TSC2 CASK	2.12e-03	1285	92	10	35914814
Cytoband	8p23.3	FBXO25 MYOM2	3.56e-04	14	92	2	8p23.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2p24	TDRD15 TTC32 DDX1	5.93e-04	81	92	3	chr2p24
Cytoband	2p24.1	TDRD15 TTC32	9.78e-04	23	92	2	2p24.1
Cytoband	Ensembl 112 genes in cytogenetic band chr7p22	ZNF12 PMS2 USP42	2.53e-03	134	92	3	chr7p22
Cytoband	4q21.1	CSN2 PPEF2	2.53e-03	37	92	2	4q21.1
GeneFamily	Cadherin related	CDHR2 FAT3 CDH23	3.05e-05	17	66	3	24
Coexpression	GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP	FOXJ2 PPM1E DLG2 TSC2 ALDOC ITGAX TPCN1	8.26e-07	147	91	7	M6765
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NAMPT FCN1 CEACAM3 RAP1GAP2 CDH23 ITGAX CYTIP	1.65e-07	195	92	7	10ce1b6961f10372d1f65388cbf3626a5fcd6840
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	NAMPT FCN1 CEACAM3 RAP1GAP2 RNF213 ITGAX CYTIP	1.77e-07	197	92	7	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	severe_influenza-Non-classical_Monocyte\|World / disease group, cell group and cell class (v2)	RNPEP FCN1 ACP2 DUSP7 CEACAM3 CDH23 PLXNB2	1.84e-07	198	92	7	790ee20abc9666b8095675b0d445c0914ee70ea3
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	RPGRIP1 NAMPT FCN1 CEACAM3 CDH23 PLXNB2	2.44e-06	186	92	6	d7da5edb2ee36f96cdd7e27eb9afcc1cbfd52bb6
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	NAMPT FCN1 RAP1GAP2 CDH23 ITGAX CYTIP	2.68e-06	189	92	6	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.12e-06	194	92	6	de9c7c602d886d0cd8bbd1d7e7744f84df951238
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.12e-06	194	92	6	49441ca0a8fa34cb847fecbb4b809dd01d879ebb
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.12e-06	194	92	6	16c6fcbd36d473b883fb5361caca86eb134767ab
ToppCell	cellseq-Immune-Immune_Myeloid-pMON-pMON\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.21e-06	195	92	6	2cb435dae2691e1250e26e59f9b8fb652a0c383e
ToppCell	Adult-Immune-monocyte-D231\|Adult / Lineage, Cell type, age group and donor	NAMPT FCN1 CEACAM3 RAP1GAP2 CDH23 CYTIP	3.21e-06	195	92	6	ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell	cellseq-Immune-Immune_Myeloid-pMON\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.21e-06	195	92	6	217908cb53016a6cb51f1bc3fc752c8df650df71
ToppCell	COVID-19_Moderate-Non-classical_Monocyte\|COVID-19_Moderate / disease group, cell group and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.31e-06	196	92	6	256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCell	Influenza_Severe-Non-classical_Monocyte\|World / Disease group and Cell class	RNPEP FCN1 ACP2 CEACAM3 CDH23 PLXNB2	3.31e-06	196	92	6	8ef9810ee99082a9c803c7ecad6ceb5710d16b54
ToppCell	COVID-19_Severe-Non-classical_Monocyte\|COVID-19_Severe / disease group, cell group and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.31e-06	196	92	6	af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCell	myeloid-CD16+_Monocyte\|World / Lineage and Cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.31e-06	196	92	6	225c102e0a2047425a7125eba1d2359159c50409
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCN1 ACP2 CEACAM3 CDH23 PLXNB2 ITGAX	3.31e-06	196	92	6	51fc8bb9a806f8fbf78d5d80d535f1068a9770c2
ToppCell	Multiple_Sclerosis-Myeloid-CD16_Mono\|Multiple_Sclerosis / Disease, Lineage and Cell Type	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.31e-06	196	92	6	83011b56780295dff5ded57064b07dcd2f19ea26
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	083fec147040ee0bebac2815fb89355cf3a7ffa5
ToppCell	severe-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	NAMPT SAMD9 DDX60 RNF213 CDK5RAP2 ITGAX	3.40e-06	197	92	6	c8a90d82170cf20e14aebecddcf7cc0ca56cda87
ToppCell	10x5'-lymph-node_spleen-Myeloid_Monocytic-Nonclassical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	67f19dd30adb03300f04219d0295bc1c1788f626
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	f0e6745b0fd734ea17e7a2a883e48017e8d3102d
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	b82142cf8057a55dfa884248b752173661edffd1
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	96d56bce69de7192c7a6b43371b56f4acdcc7733
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	70faaea9c143337a52c8f660ebb063aa92327357
ToppCell	COVID-19_Severe-Non-classical_Monocyte\|World / disease group, cell group and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	60fee75b12451206bb2c07b61651a73c59ec6ade
ToppCell	10x5'-bone_marrow-Myeloid_Monocytic-Nonclassical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	dcf1e74b7c21466d38d68f44d404bce14ade2805
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.40e-06	197	92	6	c6e977adb1248957d31300312310e08238b64236
ToppCell	PBMC-Mild-Myeloid-Non-classical_Monocyte\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	422074930fce25a6ad15ba41e391c65787e7878e
ToppCell	COVID-19_Mild-Myeloid-Non-classical_Monocyte\|COVID-19_Mild / Disease group, lineage and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.40e-06	197	92	6	9c943d18f8e6cb0ce9f2158d50796fafae5c81d4
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NAMPT FCN1 RAP1GAP2 RNF213 ITGAX CYTIP	3.51e-06	198	92	6	ea34096bee852a7e996f097fa279381afa8f86ff
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	cbbdd44dfa95370c0fbaa65ba71d86bfee0ea379
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	3bc3dbd178043deadd7eef413b2761dc003abd6e
ToppCell	Healthy-Non-classical_Monocyte\|Healthy / disease group, cell group and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	394e5fa8998c46c6f7cd57b53f347d2029c75ae1
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	9b47585653aaebd033c9b7bba93c7a7c35a4d60e
ToppCell	COVID-19_Moderate-Non-classical_Monocyte\|World / disease group, cell group and cell class	NAMPT FCN1 ACP2 CEACAM3 CDH23 PLXNB2	3.51e-06	198	92	6	8449934e20bb2a34079fb642cae0d4647b9efe51
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	8b5d30312bbcabc6911ff03e5028766d77203dff
ToppCell	Healthy-Non-classical_Monocyte\|World / disease group, cell group and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	4fd27a9fb3758c94ed9f0a726296e92b0625da44
ToppCell	Control-Myeloid-Non-classical_Monocyte\|Control / Disease group, lineage and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	ae0a51e63e2751a6d9dc0c8a3852680949173523
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	7d8fade2583c07a33dd83057cbce08e9fc77987a
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.51e-06	198	92	6	165d60b111a17d517a420c434733eefb98da240d
ToppCell	BAL-Mild-cDC_1\|Mild / Compartment, Disease Groups and Clusters	NAMPT SAMD9 FCN1 DDX60 RNF213 ITGAX	3.61e-06	199	92	6	c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.61e-06	199	92	6	e12cea071e46436835cc22fe7badcbe878a1305b
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.61e-06	199	92	6	2ff5007b971c6fca9a9ef433e257739f0322a2a5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NAMPT FCN1 CEACAM3 CDH23 ITGAX CYTIP	3.61e-06	199	92	6	87c7b8c77c28f3cfa6d6dddfd00c9d18d116207e
ToppCell	COVID-19-COVID-19_Mild-Myeloid-CD16+_Monocyte\|COVID-19_Mild / Disease, condition lineage and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.71e-06	200	92	6	5c0eb14bdf1bfeaf93f6c3d521529bd5a4de50ce
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD16\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	NAMPT FCN1 CEACAM3 RAP1GAP2 CDH23 ITGAX	3.71e-06	200	92	6	d39bf03817b76c9dfcbcd868341b51bb8601ea9b
ToppCell	MS-Multiple_Sclerosis-Myeloid-CD16+_Monocyte\|Multiple_Sclerosis / Disease, condition lineage and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.71e-06	200	92	6	add2f9fbada3a68662edc8c756af90cdc380295b
ToppCell	Control-Control-Myeloid-CD16+_Monocyte\|Control / Disease, condition lineage and cell class	NAMPT FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	3.71e-06	200	92	6	8dd124a5aca897652ea68efbfc5a167b4cf31aef
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS4 MYO5A PPEF2 ITGAX CYTIP	1.93e-05	158	92	5	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS4 MYO5A PPEF2 ITGAX CYTIP	2.05e-05	160	92	5	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 USP42 PPM1E CENPI DLG2	2.37e-05	165	92	5	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 USP42 PPM1E CENPI DLG2	2.37e-05	165	92	5	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 MYO1C HECTD2 GYS1 CYTIP	2.59e-05	168	92	5	e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDST4 PPEF2 DNAH5 SERPINA5 CNTN1	2.74e-05	170	92	5	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXJ2 CELSR2 HECTD2 PPM1E G2E3	2.82e-05	171	92	5	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXJ2 CELSR2 HECTD2 PPM1E G2E3	2.82e-05	171	92	5	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WAPL SAMD9 NRDC RNF213 MYOM2	3.32e-05	177	92	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WAPL SAMD9 NRDC RNF213 MYOM2	3.32e-05	177	92	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	WAPL SAMD9 NRDC RNF213 MYOM2	3.32e-05	177	92	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	WAPL SAMD9 NRDC RNF213 MYOM2	3.32e-05	177	92	5	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WAPL SAMD9 NRDC RNF213 MYOM2	3.32e-05	177	92	5	d5aeda113afaa2425874394610344570c9078478
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NAMPT MORN1 CDH23 PPEF2 CNTN1	3.50e-05	179	92	5	4f20540bfbcefe0e83812be7ea542e8bb3bf19bc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TDRD15 MYO5A IL1RAPL2 SCN2A DLG2	3.69e-05	181	92	5	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SCN2A MYOM2 DNAH5 CNTN1	3.99e-05	184	92	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	normal_Lymph_Node-Myeloid_cells-Monocytes\|normal_Lymph_Node / Location, Cell class and cell subclass	RPGRIP1 NAMPT FCN1 PLXNB2 ITGAX	3.99e-05	184	92	5	3cec28ff076fa53d034428de2bb1a237e0c1568c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SCN2A MYOM2 DNAH5 CNTN1	3.99e-05	184	92	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SCN2A MYOM2 DNAH5 CNTN1	3.99e-05	184	92	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-GI_small-bowel-Myeloid_Monocytic-Nonclassical_monocytes\|GI_small-bowel / Manually curated celltypes from each tissue	FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	4.21e-05	186	92	5	a16ecf70271894a842925f232009e2623d16947e
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NAMPT FCN1 CDH23 PLXNB2 ITGAX	4.65e-05	190	92	5	18c020ca9a23399214133ec255ab870e0060f2e1
ToppCell	IPF-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	NAMPT FCN1 RAP1GAP2 CDH23 CYTIP	4.65e-05	190	92	5	f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCell	Influenza_Severe-Non-classical_Monocyte\|Influenza_Severe / Disease group and Cell class	ACP2 CEACAM3 CDH23 PLXNB2 ITGAX	4.77e-05	191	92	5	197edf6feb1cfc71d88e532d74f77305a42a3486
ToppCell	IPF-Myeloid-ncMonocyte\|IPF / Disease state, Lineage and Cell class	NAMPT FCN1 RAP1GAP2 CDH23 CYTIP	4.89e-05	192	92	5	e9fb8c57d8094f70fb492909b2bec40aa5f2e5b8
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	4.89e-05	192	92	5	7bcdbd97fa8c3bfccde426d44979601226913fc3
ToppCell	mild_COVID-19_(asymptomatic)-Non-classical_Monocyte\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	ACP2 CEACAM3 CDH23 PLXNB2 ITGAX	5.01e-05	193	92	5	7839040e703877ef321494ad8926a8604729ceda
ToppCell	3'_v3-bone_marrow-Myeloid_Monocytic-Nonclassical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	NAMPT FCN1 CEACAM3 CDH23 PLXNB2	5.01e-05	193	92	5	dc309c249d569e93dc2b154e002212a6eee44497
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 CYTIP	5.01e-05	193	92	5	cb0fb21510124883e716780bea46575620c366b8
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 CYTIP	5.01e-05	193	92	5	0c207879f994c227dcd1322faa69ec9e3749cdaa
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NAMPT FCN1 CEACAM3 CDH23 CYTIP	5.01e-05	193	92	5	0fbbfcc803edc3cd96b35467ad5cc573af07fd67
ToppCell	COVID_non-vent-Myeloid-Monocytic-CD16+_Monocyte\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	NAMPT FCN1 CDH23 PLXNB2 ITGAX	5.14e-05	194	92	5	1b4a17d58793e8889484fe592dce8ee1e8fe77a9
ToppCell	nucseq-Immune-Immune_Myeloid-pMON-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAMPT FCN1 RAP1GAP2 CDH23 CYTIP	5.14e-05	194	92	5	e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NAMPT CEACAM3 CDK5RAP2 ITGAX CYTIP	5.14e-05	194	92	5	b04cbd240c59755ef7bdeb17fee3028caef6dedb
ToppCell	nucseq-Immune-Immune_Myeloid-pMON\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NAMPT FCN1 RAP1GAP2 CDH23 CYTIP	5.14e-05	194	92	5	0bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCell	severe_influenza-Non-classical_Monocyte\|severe_influenza / disease group, cell group and cell class (v2)	ACP2 CEACAM3 CDH23 PLXNB2 ITGAX	5.14e-05	194	92	5	7630e223666fb65743e21e045478f687dd739a54
ToppCell	control-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	NAMPT SAMD9 DDX60 RNF213 CDK5RAP2	5.14e-05	194	92	5	267e213e8efe53aadfe553a2ca010a0e3b4b8939
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NAMPT CEACAM3 CDK5RAP2 ITGAX CYTIP	5.14e-05	194	92	5	744fd4580942183a1058717d0c3ac86483e366ed
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NAMPT CEACAM3 CDK5RAP2 ITGAX CYTIP	5.14e-05	194	92	5	d2f6c8900b5c448eede8047ca964e94b19bd6ca5
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	5.26e-05	195	92	5	157f1f9b0521c9eba11806eb4b6802ff116ab912
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NAMPT FCN1 CDH23 ITGAX CYTIP	5.26e-05	195	92	5	1d58585557bf8e9ce4d514e128d3a902b526331d
ToppCell	distal-Hematologic-Nonclassical_Monocyte-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NAMPT FCN1 CEACAM3 CDH23 CYTIP	5.26e-05	195	92	5	935461e849ca4d17627341b3ae5124d497793a91
ToppCell	IIF-Myeloid-CD16_Mono\|IIF / Disease, Lineage and Cell Type	NAMPT FCN1 CEACAM3 CDH23 ITGAX	5.26e-05	195	92	5	87c1f52ab19b105bae3f315496c620c226a77a7f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RNPEP FCN1 CEACAM3 CDH23 ITGAX	5.26e-05	195	92	5	3a30479857fc2805df92655c9599389559b1995d
ToppCell	mild_COVID-19_(asymptomatic)-Non-classical_Monocyte\|World / disease group, cell group and cell class (v2)	ACP2 CEACAM3 CDH23 PLXNB2 ITGAX	5.26e-05	195	92	5	eb809331557f8c40de45b1208cbc49b621930a4b
ToppCell	10x5'-blood-Myeloid_Monocytic-Nonclassical_monocytes\|blood / Manually curated celltypes from each tissue	NAMPT FCN1 CEACAM3 CDH23 PLXNB2	5.26e-05	195	92	5	88d65c7c3a28922c125bd9f7c403a55d7d4d83a9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	5.26e-05	195	92	5	95327f2818bcdca53dbd2971f674a9042a1392c6
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	NAMPT FCN1 RAP1GAP2 CDH23 CYTIP	5.26e-05	195	92	5	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	severe_COVID-19-Non-classical_Monocyte\|severe_COVID-19 / disease group, cell group and cell class (v2)	RNPEP ACP2 CDH23 PLXNB2 ITGAX	5.39e-05	196	92	5	34c1c74cad5e23196e86cfd6f19c836fe57b2264
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	FCN1 RAP1GAP2 CDH23 ITGAX CYTIP	5.39e-05	196	92	5	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	(001)_CD16+_Monocyte\|World / immune cells in Peripheral Blood (logTPM normalization)	FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	5.39e-05	196	92	5	33843d550cbca03c044d593b1f6972e4d3871f7f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FCN1 CEACAM3 CDH23 PLXNB2 ITGAX	5.39e-05	196	92	5	29246378ffb1010fe6858da756ae3d13df2306ba
ToppCell	wk_15-18-Hematologic-Myeloid-Neutrophil\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NAMPT FCN1 CEACAM3 ITGAX CYTIP	5.39e-05	196	92	5	36c01e0feea33448222010c21442b9fac671bd7d
Disease	Atypical Endometrial Hyperplasia	CELSR2 DDX1	8.94e-05	5	89	2	C0349579
Disease	Complex Endometrial Hyperplasia	CELSR2 DDX1	8.94e-05	5	89	2	C0349578
Disease	Simple Endometrial Hyperplasia	CELSR2 DDX1	8.94e-05	5	89	2	C0456483
Disease	cardiovascular disease biomarker measurement, ankle brachial index	FAT3 DNAH5	8.94e-05	5	89	2	EFO_0003912, EFO_0005278
Disease	Endometrial Hyperplasia	CELSR2 DDX1	8.94e-05	5	89	2	C0014173
Disease	colorectal adenoma	FAT3 FSD2 DLG2	1.36e-04	33	89	3	EFO_0005406
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	TDRD15 CELSR2	2.49e-04	8	89	2	EFO_0008589, EFO_0008595
Disease	alpha-1-antitrypsin measurement	CELSR2 SERPINA5	3.19e-04	9	89	2	EFO_0008327
Disease	Ciliopathies	RPGRIP1 CDH23 TSC2 DNAH5	3.50e-04	110	89	4	C4277690
Disease	Nephroblastoma	DLG2 DDX1	3.98e-04	10	89	2	Orphanet_654
Disease	complement C1q tumor necrosis factor-related protein 1 measurement	CELSR2 CDH23	5.82e-04	12	89	2	EFO_0801493
Disease	granulins measurement	CELSR2 CDH23	5.82e-04	12	89	2	EFO_0008141
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	TDRD15 CELSR2	8.00e-04	14	89	2	EFO_0004611, EFO_0008589
Disease	Opioid use measurement	BEND4 MYOM2	9.21e-04	15	89	2	EFO_0009937
Disease	response to statin, LDL cholesterol change measurement	TDRD15 CELSR2	9.21e-04	15	89	2	EFO_0007804, GO_0036273
Disease	Tremor, Rubral	NPC1 ABCB7	1.05e-03	16	89	2	C0750940
Disease	Ataxia, Appendicular	NPC1 ABCB7	1.05e-03	16	89	2	C0750937
Disease	Ataxia, Motor	NPC1 ABCB7	1.05e-03	16	89	2	C0278161
Disease	Abnormal coordination	NPC1 ABCB7	1.05e-03	16	89	2	C0520966
Disease	Ataxia, Truncal	NPC1 ABCB7	1.05e-03	16	89	2	C0427190
Disease	Ataxia, Sensory	NPC1 ABCB7	1.05e-03	16	89	2	C0240991
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN2A CASK	1.05e-03	16	89	2	C0393706
Disease	autism spectrum disorder (implicated_via_orthology)	SCN2A NDST4 TSC2 CASK	1.18e-03	152	89	4	DOID:0060041 (implicated_via_orthology)
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	TDRD15 CELSR2	1.19e-03	17	89	2	EFO_0022232
Disease	Mammary Neoplasms, Experimental	RNPEP CSN2 RCN1 CASK	1.26e-03	155	89	4	C0024668
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	TDRD15 CELSR2	1.33e-03	18	89	2	EFO_0008317, EFO_0008589
Disease	Leber Congenital Amaurosis	RPGRIP1 IFT140	2.00e-03	22	89	2	C0339527
Disease	anxiety disorder (implicated_via_orthology)	SCN2A TSC2	2.00e-03	22	89	2	DOID:2030 (implicated_via_orthology)
Disease	progranulin measurement	CELSR2 CDH23	2.00e-03	22	89	2	EFO_0004625
Disease	otitis media (implicated_via_orthology)	IDUA DNAH5	2.00e-03	22	89	2	DOID:10754 (implicated_via_orthology)
Disease	West Syndrome	SCN2A TSC2	2.38e-03	24	89	2	C0037769
Disease	Ataxia	NPC1 ABCB7	2.58e-03	25	89	2	C0004134
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	THBS4 CPSF6 SCN2A ASNS CDH23 DLG2 SPA17 TAF5	2.91e-03	801	89	8	EFO_0003888, EFO_0007052, MONDO_0002491

Protein segments in the cluster

Peptide	Gene	Start	Entry
YSNNQHGFSEDFEEV	PTPRG	841	P23470
QHFEFEYQTKVDGEI	ASNS	86	P08243
QDQFDSFLKAYVHEF	RNPEP	431	Q9H4A4
GVIFFHETLYQKDDN	ALDOC	76	P09972
AEQYDAFVKFTHDQI	AKIRIN2	176	Q53H80
YEGIDHQASQDEVFN	BEND4	511	Q6ZU67
DFKEFYSESNINHEG	ADCY4	881	Q8NFM4
DTNDHDPVFEQQEYK	CELSR2	281	Q9HCU4
YNGRFNEKHDFVALE	CELSR2	1406	Q9HCU4
YFIAAGNEEKNFHLQ	CDH23	2766	Q9H251
QKAQTQEFQGSEDYE	CDK5RAP2	356	Q96SN8
EDNQSFQYDHEAFLG	RCN1	51	Q15293
HEQFTKYLNFSESEE	ITGAX	931	P20702
DFHEYKNEADHGQQA	PCDHGA8	796	Q9Y5G5
YIFIHKTEENGENQY	KBTBD3	296	Q8NAB2
DRDGQVYQGSFHDNK	MORN1	126	Q5T089
YGFVHFQKQESAERA	PABPC1L2A	131	Q5JQF8
DEENGKNYYFVSHDQ	CASK	781	O14936
DYHFQQTGQSEALEE	PTCD3	206	Q96EY7
SHEGNVEEDFYSTFQ	HECTD2	571	Q5U5R9
QDAHFEFYQSKVFLD	DDX60	1501	Q8IY21
NKQFDNYGEEFTMHD	DDX1	176	Q92499
QEIHFFDNDENYGKG	HS3ST5	121	Q8IZT8
YFFDFLDEQAEKHNI	PLXNB2	1656	O15031
HIDQVYNTFDTNKDG	GUCA1C	56	O95843
FVQDEKGAFNFDQET	DPP3	461	Q9NY33
FIEEKSSFEYGQVNH	TUBGCP2	276	Q9BSJ2
DGEIFNNEEHEYASK	FBXO25	51	Q8TCJ0
FDVDNNVLIYTHDGF	RFPL4B	221	Q6ZWI9
NHDFKFSYSEINFQD	FOXJ2	236	Q9P0K8
EEVQFFNGNNYHKGI	NDST4	631	Q9H3R1
GDEEIHATGFNYQNE	NPEPPSL1	111	A6NEC2
HATGFNYQNEDEKVT	NPEPPSL1	116	A6NEC2
EDQEEQAYFAVFDGH	PPM1E	261	Q8WY54
SQARLEKEYFDQHFG	NPC1	386	O15118
HIFELYQEDSGNFSV	ACP2	311	P11117
VDLVDFEGNHQFAKY	FCN1	206	O00602
EVAYVIENDNFGSEH	G2E3	391	Q7L622
NDDQSFYADVHVEDG	DPYSL4	26	O14531
EEAQVNFTGYVDEHA	CDHR2	366	Q9BYE9
EEFNQEAEYGGHDQI	CPSF6	16	Q16630
TSFNHKGTQEQDFYV	SERPINA5	211	P05154
SFNGYVIDFNKENIH	CNTN1	541	Q12860
FIHKDYQAEVNENVD	FAT3	1671	Q8TDW7
EIEETYANFIKHNDG	ATL2	451	Q8NHH9
QGEDEHQDKIYPSFQ	CSN2	46	P05814
LQGGFNKFQTEYSEH	DUSP7	171	Q16829
NEEATGQFHVYQENA	CEACAM3	131	P40198
EYDDTHFFKNESESN	DENND2C	101	Q68D51
EKQDNETFGFEIQSY	CYTIP	81	O60759
ASGHFTDFEDKQQVF	IDUA	136	P35475
EHKFIEAGQYNDNLY	DLG2	741	Q15700
NNYEHGKEFTNFLDT	CENPI	406	Q92674
NFNVDKEAGERQIYH	GYS1	226	P13807
QVEIDEYQNYDKAHG	IFT140	1291	Q96RY7
GDEEIHATGFNYQNE	NPEPPS	111	P55786
HATGFNYQNEDEKVT	NPEPPS	116	P55786
NFRTEHYEEQIEAFK	C9	211	P02748
DYEEFCKQTNDLHNE	DNAH5	536	Q8TE73
IEYAGQQDQVKLHDF	PPEF2	51	O14830
FYHQTEEHKFQEQVS	PIWIL1	286	Q96J94
LVYNQHENEAKSFFE	TAF5	251	Q15542
YDEHEVNNTFKFGVI	RAP1GAP2	251	Q684P5
NSFIGDGFKNQHEEE	RPGRIP1	1046	Q96KN7
FQGIKSNECEFDYHV	TDRD15	31	B5MCY1
FYKFELQHGTEEQQE	PRPF6	881	O94906
EIKEQHKNFEDFYSF	SAMD9	871	Q5K651
YRQHFGADETNDDNK	IL1RAPL2	386	Q9NP60
ENFGKQEQNFESHYN	FSD2	246	A1L4K1
QEKYDGHQQFFAIVQ	SIAH1	196	Q8IUQ4
VYKEHFQDDVFNEKG	NAMPT	86	P43490
GSKVEDRFYNNHAFE	SPA17	61	Q15506
VQDAEDQGFQFSYKE	MROH2B	766	Q7Z745
TVAFDNVHFEYIEGQ	ABCB7	471	O75027
NGESFEYEFIYKHQQ	RNF213	456	Q63HN8
FEGTFHVNTQTDDDY	THBS4	781	P35443
RFGNQEDAHEFLQYT	USP42	191	Q9H9J4
KGQYNFDHPDAFDND	UCK1	81	Q9HA47
DDEDSKQNIFHFLYG	SPDYE21	261	A0A494C086
DDEDSKQNIFHFLYG	SPDYE5	261	A6NIY4
EDKSHFYFLEGQNDA	SCN2A	321	Q99250
HFNDVVEFGENQEFT	WAPL	641	Q7Z5K2
RKIEDNEFHYQEQTD	NRDC	546	O43847
EQYLHGNKEFFQSAI	SERPINI2	121	O75830
QAHFNNGEYAEAEAL	TTC32	16	Q5I0X7
FIVDQHATDEKYNFE	PMS2	696	P54278
IYLQEGENNDKFFTH	TPCN1	76	Q9ULQ1
DTFKQNENGEYTDHL	UBP1	211	Q9NZI7
EKTHPGDQAYEFNQN	ZNF12	181	P17014
EQHGFFEQAQESYEK	TRRAP	2781	Q9Y4A5
DQNEFHGSQERYFEL	TSC2	396	P49815
YLFEQGKHEFVNDVA	TYK2	151	P29597
VENFQVHRYEGVDKN	ZMAT1	106	Q5H9K5
DIYGFEVFQHNSFEQ	MYO1C	421	O00159
QHFADKVEYQCEGFL	MYO5A	551	Q9Y4I1
YTFEIFDGKDNHQRS	MYOM2	1301	P54296