Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	CTP synthase activity	CTPS2 CTPS1	7.45e-06	2	55	2	GO:0003883
GeneOntologyBiologicalProcess	'de novo' CTP biosynthetic process	CTPS2 CTPS1	6.73e-06	2	54	2	GO:0044210
GeneOntologyBiologicalProcess	spinal cord ventral commissure morphogenesis	GLI2 DCC	2.01e-05	3	54	2	GO:0021965
GeneOntologyCellularComponent	cytoophidium	CTPS2 CTPS1	2.04e-05	3	55	2	GO:0097268
GeneOntologyCellularComponent	dynein complex	DNAH17 NUDCD3 DNAH6	3.89e-04	54	55	3	GO:0030286
GeneOntologyCellularComponent	beta-catenin-TCF complex	BCL9L TLE3	5.20e-04	13	55	2	GO:1990907
Domain	CTP_synthase_N	CTPS2 CTPS1	8.21e-06	2	54	2	IPR017456
Domain	GATase1_CTP_Synthase	CTPS2 CTPS1	8.21e-06	2	54	2	IPR033828
Domain	CTP_synthase	CTPS2 CTPS1	8.21e-06	2	54	2	IPR004468
Domain	CTP_synth_N	CTPS2 CTPS1	8.21e-06	2	54	2	PF06418
Domain	Znf_FCS	PHC1 PHC2	8.16e-05	5	54	2	IPR012313
Domain	GATase	CTPS2 CTPS1	8.16e-05	5	54	2	PF00117
Domain	GATASE	CTPS2 CTPS1	1.22e-04	6	54	2	IPR017926
Domain	ZF_FCS	PHC1 PHC2	1.22e-04	6	54	2	PS51024
Domain	GATASE_TYPE_1	CTPS2 CTPS1	1.22e-04	6	54	2	PS51273
Domain	-	CTPS2 CTPS1	3.64e-04	10	54	2	3.40.50.880
Domain	Class_I_gatase-like	CTPS2 CTPS1	5.32e-04	12	54	2	IPR029062
Domain	Tyr_Pase_AS	PTPRD DUSP15 SSH2	1.23e-03	73	54	3	IPR016130
Domain	TYR_PHOSPHATASE_1	PTPRD DUSP15 SSH2	1.97e-03	86	54	3	PS00383
Domain	PWWP	BRD1 MBD5	2.00e-03	23	54	2	PF00855
Domain	PWWP_dom	BRD1 MBD5	2.00e-03	23	54	2	IPR000313
Domain	TYR_PHOSPHATASE_2	PTPRD DUSP15 SSH2	2.04e-03	87	54	3	PS50056
Domain	TYR_PHOSPHATASE_dom	PTPRD DUSP15 SSH2	2.04e-03	87	54	3	IPR000387
Domain	PWWP	BRD1 MBD5	2.17e-03	24	54	2	PS50812
Domain	Ig_I-set	PTPRD BSG ALPK3 DCC	2.21e-03	190	54	4	IPR013098
Domain	I-set	PTPRD BSG ALPK3 DCC	2.21e-03	190	54	4	PF07679
Domain	-	PTPRD DUSP15 SSH2	2.39e-03	92	54	3	3.90.190.10
Domain	Prot-tyrosine_phosphatase-like	PTPRD DUSP15 SSH2	2.95e-03	99	54	3	IPR029021
Domain	DUSP	DUSP15 SSH2	3.62e-03	31	54	2	IPR024950
Domain	TYR_PHOSPHATASE_DUAL	DUSP15 SSH2	4.34e-03	34	54	2	PS50054
Domain	TYR_PHOSPHATASE_DUAL_dom	DUSP15 SSH2	4.59e-03	35	54	2	IPR020422
Domain	DSPc	DUSP15 SSH2	4.59e-03	35	54	2	SM00195
Domain	IGc2	PTPRD BSG ALPK3 DCC	4.72e-03	235	54	4	SM00408
Domain	Ig_sub2	PTPRD BSG ALPK3 DCC	4.72e-03	235	54	4	IPR003598
Domain	Dual-sp_phosphatase_cat-dom	DUSP15 SSH2	6.26e-03	41	54	2	IPR000340
Domain	DSPc	DUSP15 SSH2	6.26e-03	41	54	2	PF00782
Domain	IG	PTPRD SLAMF9 BSG ALPK3 DCC	7.26e-03	421	54	5	SM00409
Domain	Ig_sub	PTPRD SLAMF9 BSG ALPK3 DCC	7.26e-03	421	54	5	IPR003599
Domain	fn3	PTPRD DCC IL27RA	1.15e-02	162	54	3	PF00041
Domain	-	PTPRD SLAMF9 BSG ALPK3 DCC IL27RA	1.19e-02	663	54	6	2.60.40.10
Domain	IG_LIKE	PTPRD SLAMF9 BSG ALPK3 DCC	1.35e-02	491	54	5	PS50835
Pathway	KEGG_MEDICUS_REFERENCE_DEUBIQUITINATION_OF_H2AK119	MBD5 PHC1 PHC2	6.55e-05	26	43	3	M47923
Pubmed	Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.	CTPS2 CTPS1	2.46e-06	2	55	2	20739275
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	BBX PTPRD KLF10 DNAH17 PLCB1 DCC	3.92e-06	265	55	6	19240061
Pubmed	Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes.	PHC1 PHC2	7.36e-06	3	55	2	17215307
Pubmed	Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.	CTPS2 CTPS1	7.36e-06	3	55	2	16179339
Pubmed	Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse.	PLCB1 ITPR1	7.36e-06	3	55	2	10570150
Pubmed	Inositol 1,4,5-trisphosphate receptors selectively localized to the acrosomes of mammalian sperm.	PLCB1 ITPR1	7.36e-06	3	55	2	7642703
Pubmed	Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic.	PHC1 PHC2	7.36e-06	3	55	2	9121482
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	INTS6 BBX GLI2 BRD1 MBD5 TBCEL ITPR1	2.13e-05	536	55	7	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	INTS6 BBX GLI2 BRD1 MBD5 TBCEL ITPR1	2.18e-05	538	55	7	10512203
Pubmed	Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons.	GLI2 DCC	2.45e-05	5	55	2	34169076
Pubmed	RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor.	PHC1 PHC2	2.45e-05	5	55	2	9199346
Pubmed	An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.	PLCB1 ITPR1	2.45e-05	5	55	2	26075576
Pubmed	Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice.	CTPS2 CTPS1	3.67e-05	6	55	2	38438357
Pubmed	Ventral midline cells are required for the local control of commissural axon guidance in the mouse spinal cord.	GLI2 DCC	3.67e-05	6	55	2	10409510
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	HIVEP1 BBX KLF10 PHF20L1 TLE3 ETV5 PHC1 ZNF646	3.80e-05	808	55	8	20412781
Pubmed	Genetic dissection of gustatory sensitivity to bitterness (sucrose octaacetate) in mice.	PLCB1 ITPR1	5.13e-05	7	55	2	10609087
Pubmed	MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1.	PHC1 PHC2	5.13e-05	7	55	2	15563468
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	LENG8 BCL9L HIVEP1 TLE3 MED14	6.65e-05	268	55	5	33640491
Pubmed	MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells.	PHC1 PHC2	6.83e-05	8	55	2	19369945
Pubmed	Molecular control of spinal accessory motor neuron/axon development in the mouse spinal cord.	GLI2 DCC	6.83e-05	8	55	2	16267219
Pubmed	Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.	BCL9L TLE3	6.83e-05	8	55	2	28296634
Pubmed	Human transcription factor protein interaction networks.	LENG8 BCL9L HIVEP1 BBX KLF10 BSG GLI2 TLE3 ETV5 SLX4	7.19e-05	1429	55	10	35140242
Pubmed	Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.	LENG8 INTS6 MED14	8.77e-05	54	55	3	16239144
Pubmed	Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx.	PLCB1 ITPR1	8.78e-05	9	55	2	15623527
Pubmed	RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3.	PHC1 PHC2	8.78e-05	9	55	2	22325148
Pubmed	CTPS and IMPDH form cytoophidia in developmental thymocytes.	CTPS2 CTPS1	1.10e-04	10	55	2	34022203
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	PTPRD SLAMF9 BSG DCC	1.29e-04	162	55	4	25826454
Pubmed	Mammalian polyhomeotic homologues Phc2 and Phc1 act in synergy to mediate polycomb repression of Hox genes.	PHC1 PHC2	1.34e-04	11	55	2	16024804
Pubmed	Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice.	PHC1 PHC2	1.34e-04	11	55	2	12183370
Pubmed	Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.	PTPRD PHF20L1 TLE3 DCC	1.38e-04	165	55	4	16107646
Pubmed	PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.	MED14 PHC1 PHC2	1.52e-04	65	55	3	22496869
Pubmed	Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus.	PHC1 PHC2	1.60e-04	12	55	2	19636380
Pubmed	Sall1 balances self-renewal and differentiation of renal progenitor cells.	BBX ETV5 CDH4	1.67e-04	67	55	3	24550112
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	MED14 PHC1 PHC2	1.82e-04	69	55	3	28481362
Pubmed	Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion.	GLI2 DCC	1.89e-04	13	55	2	25366972
Pubmed	Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy.	PHC1 PHC2	1.89e-04	13	55	2	11950896
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PDE4C HIVEP1 TLE3 MED14 RRBP1 CTPS1 PHC2	2.11e-04	774	55	7	15302935
Pubmed	A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening.	KLF10 PHC2	2.21e-04	14	55	2	10976766
Pubmed	Dorsally derived netrin 1 provides an inhibitory cue and elaborates the 'waiting period' for primary sensory axons in the developing spinal cord.	GLI2 DCC	2.21e-04	14	55	2	16510500
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH17 DNAH6	2.21e-04	14	55	2	9373155
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	PLCB1 SSH2 DNAH6 PCNT	2.23e-04	187	55	4	26460568
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GORASP2 PTPRD BSG TLE3 SSH2 NUDCD3 PCNT ITPR1	2.31e-04	1049	55	8	27880917
Pubmed	Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor.	PHC1 PHC2	2.54e-04	15	55	2	20601937
Pubmed	Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.	PLCB1 ITPR1	2.54e-04	15	55	2	28578927
Pubmed	The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.	PHC1 PHC2	2.90e-04	16	55	2	12167701
Pubmed	Role of histone H2A ubiquitination in Polycomb silencing.	PHC1 PHC2	2.90e-04	16	55	2	15386022
Pubmed	Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord.	GLI2 DCC	2.90e-04	16	55	2	28434801
Pubmed	SP8 regulates signaling centers during craniofacial development.	GLI2 ETV5	4.13e-04	19	55	2	23872235
Pubmed	alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.	GLI2 PCNT	4.13e-04	19	55	2	16543460
Pubmed	Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1.	PHC1 PHC2	4.13e-04	19	55	2	15741318
Pubmed	Defining the membrane proteome of NK cells.	GALNT1 BSG GLE1 MED14 CTPS1 ALG12 PCNT ITPR1	4.74e-04	1168	55	8	19946888
Pubmed	A role for the primary cilium in Notch signaling and epidermal differentiation during skin development.	GLI2 PCNT	5.06e-04	21	55	2	21703454
Pubmed	Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.	GLI2 PCNT	5.06e-04	21	55	2	22007132
Pubmed	SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.	PHC1 PHC2	5.06e-04	21	55	2	37014752
Pubmed	PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.	PHC1 PHC2	5.06e-04	21	55	2	18311137
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	BBX MED14 BRD1 PHC1 PHC2 PCNT	5.33e-04	645	55	6	25281560
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	KLF10 GLI2 TLE3 CDH4 PHC1	5.54e-04	424	55	5	21731673
Pubmed	A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development.	GLI2 ETV5	6.08e-04	23	55	2	29532549
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	LENG8 MED14 RRBP1 SLX4 ITPR1	6.55e-04	440	55	5	34244565
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PLCB1 ITPR1	6.63e-04	24	55	2	10843712
Pubmed	Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis.	GLI2 ETV5	7.79e-04	26	55	2	23754280
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	INTS6 RRBP1 CTPS1 SLX4	7.94e-04	262	55	4	36880596
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	LENG8 BSG RRBP1 CTPS1 PCNT	1.02e-03	486	55	5	30940648
Pubmed	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	PTPRD ITPR1	1.04e-03	30	55	2	22837378
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	LENG8 INTS6 BSG UNC13D SSH2 BRD1 ALG12 PCNT	1.09e-03	1327	55	8	32694731
Pubmed	PAR3 restricts the expansion of neural precursor cells by regulating hedgehog signaling.	GLI2 PCNT	1.26e-03	33	55	2	36218069
Pubmed	Hypertrophic Cardiomyopathy Overview	KLF10 ALPK3	1.33e-03	34	55	2	20301725
Pubmed	Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.	BCL9L TLE3	1.33e-03	34	55	2	30894540
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PLCB1 SFI1 NUDCD3 RRBP1 ZNF646	1.49e-03	529	55	5	14621295
Pubmed	GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.	GLI2 ETV5	1.58e-03	37	55	2	22465667
Pubmed	A complex oscillating network of signaling genes underlies the mouse segmentation clock.	BCL9L KLF10	1.58e-03	37	55	2	17095659
Cytoband	20p12	PLCB1 RRBP1	1.32e-04	14	56	2	20p12
Cytoband	8q22.2	KLF10 ERICH5	3.64e-04	23	56	2	8q22.2
Cytoband	Xq21.1	RTL3 TENT5D	7.53e-04	33	56	2	Xq21.1
Cytoband	22q13.33	BRD1 ALG12	9.99e-04	38	56	2	22q13.33
Cytoband	19p13.11	PDE4C IL27RA	3.63e-03	73	56	2	19p13.11
Cytoband	11q23.3	BCL9L TBCEL	4.14e-03	78	56	2	11q23.3
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PTPRD BSG ALPK3 DCC	6.23e-04	161	44	4	593
GeneFamily	Dyneins, axonemal	DNAH17 DNAH6	7.69e-04	17	44	2	536
GeneFamily	PWWP domain containing	BRD1 MBD5	1.30e-03	22	44	2	1147
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	BSG CR1	3.65e-03	37	44	2	454
GeneFamily	Fibronectin type III domain containing	PTPRD DCC IL27RA	6.91e-03	160	44	3	555
GeneFamily	Immunoglobulin like domain containing	BSG ALPK3 DCC	1.15e-02	193	44	3	594
Coexpression	TRAVAGLINI_LUNG_NEUTROPHIL_CELL	CLEC4D TLE3 CMTM2 DNAH17 UNC13D CR1 PHC2	1.11e-05	366	55	7	M41688
Coexpression	RAPA_EARLY_UP.V1_UP	HIVEP1 PTPRD TLE3 NUDCD3 CDH4	2.66e-05	167	55	5	M2644
ToppCell	myeloid-CD14+_Monocyte\|myeloid / Lineage and Cell class	KLF10 CLEC4D TLE3 CMTM2 CR1	4.64e-06	195	56	5	60fab0c24c827567fb42bbd7eb165bf45178c198
ToppCell	medial-2-Hematologic-Classical_Monocyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLEC4D TLE3 SSH2 CR1 PHC2	4.87e-06	197	56	5	fbff79d6ece1605126ae0caa0c71253ea557779c
ToppCell	medial-Hematologic-Classical_Monocyte\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLEC4D TLE3 SSH2 CR1 PHC2	4.87e-06	197	56	5	3960eac4b6753e3294e13901f6ea13d894275c8d
ToppCell	medial-Hematologic-Classical_Monocyte-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLEC4D TLE3 SSH2 CR1 PHC2	4.87e-06	197	56	5	ae2b51d4e91126ee0a0f69c040297c2a78ce27dd
ToppCell	severe-Myeloid-Neutrophils_4\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLEC4D TLE3 CMTM2 CR1 PHC2	5.25e-06	200	56	5	b665f36dcf3c9d3981ee96f2973512f751612542
ToppCell	AT1-AT2_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	KANK4 UNC13D GGTLC2 DCC	4.33e-05	155	56	4	010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLCB1 ETV5 DUSP15 GPR179	7.09e-05	176	56	4	77c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TLE3 CMTM2 SSH2 PHC2	8.07e-05	182	56	4	dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD BSG TENT5D ITPR1	9.34e-05	189	56	4	ce3fbaf9642785c8adf6edaeae20998bca558928
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 PLCB1 PHC2 ITPR1	9.34e-05	189	56	4	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 PLCB1 PHC2 ITPR1	9.53e-05	190	56	4	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 PLCB1 PHC2 ITPR1	9.53e-05	190	56	4	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD BSG TENT5D ITPR1	9.53e-05	190	56	4	db19c72d8c8053262b535068c5a9d4d696989cb1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 PLCB1 PHC2 ITPR1	9.73e-05	191	56	4	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLI2 PLCB1 PHC2 ITPR1	9.73e-05	191	56	4	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 PLCB1 RRBP1 MBD5	9.92e-05	192	56	4	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BSG CR1 TBCEL PCNT	1.01e-04	193	56	4	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 PLCB1 RRBP1 MBD5	1.01e-04	193	56	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	control-Myeloid-Neutrophils_3\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLEC4D CMTM2 CR1 PHC2	1.01e-04	193	56	4	56daf3c59a124dd068af5409113913d9ee81a454
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PTPRD GLI2 ETV5 CDH4	1.03e-04	194	56	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	Control-Classical_Monocyte\|Control / Disease condition and Cell class	CLEC4D CMTM2 PLCB1 CR1	1.03e-04	194	56	4	9e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCell	COVID_vent-Myeloid-Monocytic-Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CLEC4D CMTM2 CR1 PHC2	1.03e-04	194	56	4	eb23b171e429165dd26a64377eae7fa2ce25f547
ToppCell	control-Myeloid-Neutrophils_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLEC4D CMTM2 CR1 PHC2	1.03e-04	194	56	4	2218e6677dc6781a6e4ef3a315f2298cc2cd9df2
ToppCell	myeloid-Monocyte-CD14+_Monocyte\|myeloid / Lineage, cell class and subclass	CLEC4D CMTM2 CR1 PHC2	1.05e-04	195	56	4	15ba9c5f6ecb6ae2c603e6b036eb92b00b46f13f
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KLF10 PLCB1 SSH2 PHC2	1.05e-04	195	56	4	81a28289eda1a8a1a31b7357106f64ac5000e172
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PTPRD GLI2 ETV5 MBD5	1.05e-04	195	56	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	control-Myeloid-Neutrophils_1\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TLE3 CMTM2 SSH2 PHC2	1.07e-04	196	56	4	9c8623232c47af5de9f360fd5c5113362e37c6c9
ToppCell	mild-Myeloid-Neutrophils_4\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TLE3 CMTM2 CR1 PHC2	1.07e-04	196	56	4	f8c98cded5550843322b1711e1a57c7e88cae861
ToppCell	mild-Myeloid-Neutrophils_2\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLEC4D CMTM2 CR1 PHC2	1.07e-04	196	56	4	e9f30eb8a3915c3b2af009c832bff9b349b65ae5
ToppCell	severe-Lymphocytic-CD4_T_cells_2\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLEC4D CMTM2 CR1 PHC2	1.10e-04	197	56	4	3b71e523d8a68f131def17233385df371db70db5
ToppCell	COVID-19_Mild-Classical_Monocyte\|COVID-19_Mild / Disease condition and Cell class	CLEC4D TLE3 PLCB1 CR1	1.12e-04	198	56	4	30ada3de865b6fb2b14196a1cbfd4740c6a57ce3
ToppCell	severe-Myeloid-Neutrophils_4\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TLE3 CMTM2 CR1 PHC2	1.14e-04	199	56	4	50242666def13e5d4149c563ae000d6768f086f7
ToppCell	severe-Classical_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KLF10 CLEC4D TLE3 CR1	1.16e-04	200	56	4	f46689940fdea500ce2457eec412dd2c46705819
ToppCell	severe-Neutrophil\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CLEC4D TLE3 CMTM2 CR1	1.16e-04	200	56	4	f04d5951bac4dee47c22aaf7973312ca797f322e
ToppCell	severe-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KLF10 CLEC4D TLE3 CR1	1.16e-04	200	56	4	db7046741706376682d164c385c4701aebefc2e6
Disease	eosinophilic esophagitis	GALNT1 PTPRD DCC ERICH5 MTCH1	1.35e-05	163	55	5	EFO_0004232
Disease	3-hydroxy-1-methylpropylmercapturic acid measurement	PTPRD RTL3 ALPK3 PLCB1 ITPR1	5.01e-04	352	55	5	EFO_0007015
Disease	obesity (implicated_via_orthology)	GORASP2 PLCB1 ETV5 ITPR1	6.99e-04	215	55	4	DOID:9970 (implicated_via_orthology)
Disease	social interaction measurement	HIVEP1 KANK4 MBD5	7.28e-04	94	55	3	EFO_0009592
Disease	neurotic disorder	HIVEP1 BBX DCC	8.97e-04	101	55	3	EFO_0004257
Disease	plasma clusterin measurement	BBX PTPRD	9.96e-04	25	55	2	EFO_0007656
Disease	smoking status measurement, Cannabis use, schizophrenia	DCC PHC2	1.34e-03	29	55	2	EFO_0006527, EFO_0007585, MONDO_0005090
Disease	neuroticism measurement	HIVEP1 CTPS2 BBX DCC MBD5 ITPR1 ZNF646	1.44e-03	909	55	7	EFO_0007660
Disease	loneliness measurement	HIVEP1 PTPRD MBD5	1.62e-03	124	55	3	EFO_0007865
Disease	t-tau measurement	DMGDH NUDCD3 CDH4	1.70e-03	126	55	3	EFO_0004760
Disease	sleep apnea measurement, obstructive sleep apnea	PLCB1 CDH4	1.74e-03	33	55	2	EFO_0003918, EFO_0007817
Disease	plasma betaine measurement	DMGDH DCC	1.84e-03	34	55	2	EFO_0007787

Protein segments in the cluster

Peptide	Gene	Start	Entry
KMPRVPGHHNGVTIP	BRD1	951	O95696
THDGQPKEMPQAPVL	BBX	921	Q8WY36
MLPAQPPHEGSVEQV	ALPK3	1001	Q96L96
AQMQQGPEAHKEPPA	GLE1	351	Q53GS7
PGGVAMQRLHQLVPP	ALG12	371	Q9BV10
DGMTPKGPNHPVQVM	GLRA3	396	O75311
KGPNHPVQVMPKSPD	GLRA3	401	O75311
AGPQNKHKRPGEPNM	INTS6	636	Q9UL03
GQMHPPHGSVTPQKN	DCC	1081	P43146
HIMPGVGLPELVNPG	GORASP2	326	Q9H8Y8
EKVQPPGPVKEMAHG	NUDCD3	131	Q8IVD9
QVKPGSVPMQVPLEG	GPR179	41	Q6PRD1
IGLLGHPPHMNVNPQ	ITPR1	2741	Q14643
HQGTLNQPPVPGMDE	LENG8	136	Q96PV6
PGLGRIMQAPVPHSQ	PDE4C	101	Q08493
SGQPHMEQVPEAQPL	IL27RA	566	Q6UWB1
SNMPAKPGHLGHPQQ	GLI2	1271	P10070
PTIMVGQDGQPPSHA	GGTLC2	111	Q14390
PPAHGFQSPMGIKQE	ETV5	281	P41161
VPGAHPQPRMDGGAK	PCNT	1961	O95613
MAPVQLENHQLVPPG	MED14	1	O60244
VQKPHEGPGEMGKPV	GALNT1	51	Q10472
LPGQMNPVLPVVHFE	DNAH6	4081	Q9C0G6
NPPDPVNGMVHVIKG	CR1	106	P17927
EEGNIPLIHKNMPPV	DNAH17	571	Q9UFH2
EDPGPTQHPKEQLIM	DUSP15	226	Q9H1R2
LPEPMGTANIQLHGP	BSG	206	P35613
PPQQGMVPHGLHQGV	BCL9L	1406	Q86UU0
QQPEAMGHVPSKAPG	CDH4	801	P55283
PDILPMVGPHQGVRN	DMGDH	376	Q9UI17
NLPLPTVKPGHMNHG	MBD5	406	Q9P267
GAEPPEGVVKVPNHL	KANK4	231	Q5T7N3
QVPKGAVMFVVPQPV	KLF10	311	Q13118
VMNDPFHKTPEGPGN	ERICH5	281	Q6P6B1
PPTNHEIMPGGSVNI	PTPRD	241	P23468
GLHVENVPKMVFPQP	PHF20L1	241	A8MW92
IQVGHEPMPPTLGTN	MTCH1	106	Q9NZJ7
PPMAHEIPTVLEGQG	RTL3	126	Q8N8U3
KPQEHGLGMAQPAAP	SFI1	1026	A8K8P3
ALMPGIVQEGPGPHA	PRR20G	131	P0DPQ3
PIHGKGNFPTMEVKP	TENT5D	26	Q8NEK8
PVVVDMPEHNPGQMG	CTPS1	431	P17812
EKMGQCALPPPQGQH	SLX4	921	Q8IY92
PQSKLEGGMHPQLIP	CLEC4D	6	Q8WXI8
HMLVPPPGKEKGPQQ	CMTM2	211	Q8TAZ6
PLVIDMPEHNPGNLG	CTPS2	431	Q9NRF8
PHQQAIVTAMPGGLP	PHC2	491	Q8IXK0
EVPMVVVPPVGAKGN	RRBP1	176	Q9P2E9
LIQPGHVPEMANKFP	SSH2	576	Q76I76
GPIPEGGSNKPQHMA	ZNF646	1126	O15015
GAAKMSAAQQPPPHI	PHC1	511	P78364
PGKEGHPATIMVTNP	SLAMF9	66	Q96A28
MAGAQPGVHALQLKP	PLCB1	1	Q9NQ66
GQMQPVPFPHDALAG	TLE3	456	Q04726
HHQPMVQGIPEAGKA	UNC13D	476	Q70J99
MAPQVHPPGLALNAV	HIVEP1	2506	P15822
GVHVPATPQGSPMKD	TBCEL	31	Q5QJ74