Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of SNARE complex assembly

TRIM9 ANKRD27

9.38e-063372GO:0035544
GeneOntologyBiologicalProcessnegative regulation of vesicle fusion

TRIM9 ANKRD27

4.68e-056372GO:0031339
GeneOntologyBiologicalProcessnegative regulation of lens fiber cell differentiation

SPRY1 SPRED2

4.68e-056372GO:1902747
GeneOntologyBiologicalProcessregulation of lens fiber cell differentiation

SPRY1 SPRED2

1.40e-0410372GO:1902746
DomainCOS_domain

TRIM67 TRIM36 TRIM9

1.31e-0612353IPR017903
DomainCOS

TRIM67 TRIM36 TRIM9

1.31e-0612353PS51262
DomainZnf_RING_CS

RAD18 TRIM67 TRIM36 TRIM9 RNF182

1.25e-05163355IPR017907
DomainZnf_C3HC4_RING-type

RAD18 TRIM67 TRIM36 TRIM9 RNF182

1.62e-05172355IPR018957
Domain-

MYRIP DIDO1 RAD18 TRIM67 TRIM36 TRIM9 RNF182

1.66e-054493573.30.40.10
DomainZnf_RING/FYVE/PHD

MYRIP DIDO1 RAD18 TRIM67 TRIM36 TRIM9 RNF182

1.92e-05459357IPR013083
Domainzf-C3HC4

RAD18 TRIM67 TRIM36 TRIM9 RNF182

5.62e-05223355PF00097
DomainSPR

SPRY1 SPRED2

7.12e-057352PS51227
DomainSprouty

SPRY1 SPRED2

7.12e-057352IPR007875
DomainSprouty

SPRY1 SPRED2

7.12e-057352PF05210
DomainZF_RING_1

RAD18 TRIM67 TRIM36 TRIM9 RNF182

1.96e-04291355PS00518
DomainZF_RING_2

RAD18 TRIM67 TRIM36 TRIM9 RNF182

2.19e-04298355PS50089
DomainRING

RAD18 TRIM67 TRIM36 TRIM9 RNF182

2.44e-04305355SM00184
DomainBBOX

TRIM67 TRIM36 TRIM9

2.90e-0469353SM00336
DomainLIM

ABLIM2 PRICKLE3 CSRP2

2.90e-0469353PF00412
Domain-

ABLIM2 PRICKLE3 CSRP2

3.03e-04703532.10.110.10
DomainLIM_DOMAIN_2

ABLIM2 PRICKLE3 CSRP2

3.16e-0471353PS50023
DomainZnf_LIM

ABLIM2 PRICKLE3 CSRP2

3.16e-0471353IPR001781
DomainLIM_DOMAIN_1

ABLIM2 PRICKLE3 CSRP2

3.16e-0471353PS00478
Domain-

TRIM67 TRIM36 TRIM9

3.16e-04713534.10.45.10
DomainLIM

ABLIM2 PRICKLE3 CSRP2

3.16e-0471353SM00132
Domainzf-B_box

TRIM67 TRIM36 TRIM9

3.29e-0472353PF00643
DomainZnf_RING

RAD18 TRIM67 TRIM36 TRIM9 RNF182

3.32e-04326355IPR001841
DomainBbox_C

TRIM67 TRIM9

3.53e-0415352IPR003649
DomainBBC

TRIM67 TRIM9

3.53e-0415352SM00502
DomainZF_BBOX

TRIM67 TRIM36 TRIM9

4.49e-0480353PS50119
DomainZnf_B-box

TRIM67 TRIM36 TRIM9

4.65e-0481353IPR000315
DomainSPRY

TRIM67 TRIM36 TRIM9

7.19e-0494353PF00622
DomainSPRY_dom

TRIM67 TRIM36 TRIM9

7.19e-0494353IPR003877
DomainB30.2/SPRY

TRIM67 TRIM36 TRIM9

7.42e-0495353IPR001870
DomainB302_SPRY

TRIM67 TRIM36 TRIM9

7.42e-0495353PS50188
DomainZnf_MYND

SMYD4 SMYD5

7.70e-0422352IPR002893
DomainZF_MYND_1

SMYD4 SMYD5

7.70e-0422352PS01360
DomainZF_MYND_2

SMYD4 SMYD5

7.70e-0422352PS50865
DomainEGF_CA

FBLN7 SCUBE2 PAMR1

1.53e-03122353SM00179
DomainEGF-like_Ca-bd_dom

FBLN7 SCUBE2 PAMR1

1.60e-03124353IPR001881
DomainEGF

FBLN7 SCUBE2 PAMR1

1.68e-03126353PF00008
DomainSET

SMYD4 SMYD5

2.67e-0341352PF00856
DomainSET

SMYD4 SMYD5

3.35e-0346352SM00317
Domainfn3

TRIM67 TRIM36 TRIM9

3.42e-03162353PF00041
DomainCUB

SCUBE2 PAMR1

3.80e-0349352PF00431
DomainSET_dom

SMYD4 SMYD5

3.95e-0350352IPR001214
DomainCUB

SCUBE2 PAMR1

3.95e-0350352SM00042
DomainSET

SMYD4 SMYD5

3.95e-0350352PS50280
DomainSushi

FBLN7 PAMR1

4.27e-0352352PF00084
Domain-

SCUBE2 PAMR1

4.27e-03523522.60.120.290
DomainCUB

SCUBE2 PAMR1

4.43e-0353352PS01180
DomainCCP

FBLN7 PAMR1

4.59e-0354352SM00032
DomainSUSHI

FBLN7 PAMR1

4.93e-0356352PS50923
DomainFN3

TRIM67 TRIM36 TRIM9

4.96e-03185353SM00060
DomainSushi_SCR_CCP_dom

FBLN7 PAMR1

5.10e-0357352IPR000436
DomainCUB_dom

SCUBE2 PAMR1

5.10e-0357352IPR000859
DomainFN3

TRIM67 TRIM36 TRIM9

6.07e-03199353PS50853
DomainFN3_dom

TRIM67 TRIM36 TRIM9

6.95e-03209353IPR003961
DomainConA-like_dom

TRIM67 TRIM36 TRIM9

7.90e-03219353IPR013320
DomainEGF_3

FBLN7 SCUBE2 PAMR1

9.57e-03235353PS50026
DomainEGF

FBLN7 SCUBE2 PAMR1

9.57e-03235353SM00181
Pubmed

Microglia regulate brain progranulin levels through the endocytosis/lysosomal pathway.

GRN NLK

6.96e-06438234618685
Pubmed

A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance.

TRIM67 TRIM9

6.96e-06438231820781
Pubmed

Cosuppression of Sprouty and Sprouty-related negative regulators of FGF signalling in prostate cancer: a working hypothesis.

SPRY1 SPRED2

6.96e-06438226075267
Pubmed

Negative regulation of lens fiber cell differentiation by RTK antagonists Spry and Spred.

SPRY1 SPRED2

1.74e-05638229501879
Pubmed

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.

TRIM67 TRIM36

1.74e-05638216434393
Pubmed

Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth.

SPRY1 SPRED2

1.74e-05638238391903
Pubmed

Mammalian TRIM67 Functions in Brain Development and Behavior.

TRIM67 TRIM9

1.74e-05638229911180
Pubmed

Negative regulation of TGFβ-induced lens epithelial to mesenchymal transition (EMT) by RTK antagonists.

SPRY1 SPRED2

1.74e-05638225576668
Pubmed

TRIM67 protein negatively regulates Ras activity through degradation of 80K-H and induces neuritogenesis.

TRIM67 TRIM9

2.43e-05738222337885
Pubmed

Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.

SPRY1 SPRED2

7.62e-051238217974561
Pubmed

Cardiac deletion of Smyd2 is dispensable for mouse heart development.

SMYD4 SMYD5

9.00e-051338220305823
Pubmed

Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway.

SMYD4 SMYD5

1.38e-041638225077969
Pubmed

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

EEF2KMT SPRY1 GRN NADSYN1 ODF1 SPRED2 TRIM9 NLK

1.63e-04147738831515488
Pubmed

Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme.

SPRY1 SPRED2

2.90e-042338220934536
Pubmed

The tripartite motif family identifies cell compartments.

TRIM36 TRIM9

9.28e-044138211331580
GeneFamilyRing finger proteins

RAD18 TRIM67 TRIM36 TRIM9 RNF182

1.67e-0527522558
GeneFamilyLIM domain containing

ABLIM2 PRICKLE3 CSRP2

4.86e-05592231218
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM67 TRIM36 TRIM9

2.01e-049522359
GeneFamilyZinc fingers MYND-type

SMYD4 SMYD5

2.93e-042122287
GeneFamilyFibronectin type III domain containing

TRIM67 TRIM36 TRIM9

9.26e-04160223555
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

FBLN7 PAMR1

2.17e-03572221179
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPRY1 FBLN7 TRIM67 SCUBE2 ABLIM2 PAMR1

1.10e-08185386355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCRG1 FBLN7 SCUBE2 OTOGL CRISPLD1

7.00e-0719838555f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCRG1 FBLN7 SCUBE2 OTOGL CRISPLD1

7.00e-07198385c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPRY1 TRIM9 CRISPLD1 CSRP2

1.14e-05164384b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 PLAC8 CSRP2

1.47e-051753842e54961846c65b185d9bd6e305dd81205579d890
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 PLAC8 CSRP2

1.47e-05175384efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 DEFB124 CSRP2

1.54e-051773846f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 RAD18 PAMR1 RNF182

1.75e-05183384ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 PLAC8 CSRP2

1.95e-051883845eb107122064f0a99dfd445cc87d3766f7257216
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

MYRIP CRISPLD1 PLAC8 CSRP2

1.95e-051883842777eb7689b271c199021fe7d9db88ccebff14de
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 PLAC8 CSRP2

2.03e-05190384e1b721bb74561fe51c53328a0394c9954e489049
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 PLAC8 CSRP2

2.03e-05190384d072bb285bd34d518b958e7c9ad44739c60b359c
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 PLAC8 CSRP2

2.08e-05191384d162917816dd2e4767c97447c1cddae9397713ab
ToppCellP03-Endothelial-large_vessel_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 PLAC8 CSRP2

2.08e-05191384b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCellP15-Endothelial-large_vessel_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 PLAC8 CSRP2

2.16e-051933845f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPRY1 TRIM67 PAMR1 CSRP2

2.21e-051943847bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPRY1 TRIM67 PAMR1 CSRP2

2.21e-0519438419e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCell15-Trachea-Epithelial-Epithelial|Trachea / Age, Tissue, Lineage and Cell class

SCRG1 TRIM36 TRIM9 CSRP2

2.25e-051953849e9283a397f56732a0a5f2e2527f154d4c2dd56a
ToppCellIPF-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

MYRIP SPRY1 ABLIM2 NLK

2.39e-05198384b8bd1ba268480f54451648e01631b615a3401144
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRC SCRG1 PAMR1 CSRP2

2.44e-0519938483383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCelldistal-1-mesenchymal-Lipofibroblast|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FBLN7 PAMR1 CRISPLD1 DEFB124

2.44e-05199384a8293db3c42a8d30897858b49aae7acfc18663ba
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

HRC OTOGL DEFB124

3.18e-0572383af3077e43d4b7abfd99146a71961142f946af136
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

HRC OTOGL DEFB124

3.18e-0572383e13ee52d9a795cdc35068b0d8f8e6ed92adf8b66
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

HRC OTOGL DEFB124

5.42e-058638380aa7f0a7e43f8278b1af25ced8c069325ed3270
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Olfr558_(Mural.Rgs5Acta2.Olfr558)-|Striatum / BrainAtlas - Mouse McCarroll V32

HRC OTOGL DEFB124

8.75e-05101383a05293ccd1de48ed8c7d1417f410d2c4be388c5b
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Olfr558_(Mural.Rgs5Acta2.Olfr558)|Striatum / BrainAtlas - Mouse McCarroll V32

HRC OTOGL DEFB124

8.75e-05101383b75b000b7899399d1e6aa692d2a4c33b41a1fe18
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)|Cerebellum / BrainAtlas - Mouse McCarroll V32

HRC SCUBE2 DEFB124

2.02e-041343831fa13185a4dfb4563473184c0c4f449011d88631
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

HRC SCUBE2 DEFB124

2.02e-041343831ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Cerebellum / BrainAtlas - Mouse McCarroll V32

HRC SCUBE2 DEFB124

2.02e-041343838a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HRC OTOGL DEFB124

2.06e-04135383e908aacb72a8c340f06cf5b4a6b70c2faac4d027
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Erythroid|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EAPP PRICKLE3 RNF182

2.25e-04139383d96e5c17582f1576fa09d6bad35c418b6248448c
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FBLN7 TRIM36 CSRP2

2.39e-04142383ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Cortical_neuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

TRIM36 RNF182 CSRP2

2.70e-04148383a1269312903fc27830c1835dabf660c659a711be
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FBLN7 PAMR1 RNF182

2.76e-041493838638b3819193d11411df58964069fec583f617f4
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FBLN7 PAMR1 RNF182

2.81e-041503832ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-NP|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FBLN7 PAMR1 RNF182

2.92e-04152383b6a7453fbf9f898e4f222b215907c9a110baa2f6
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

HRC SPRY1 TRIM67

3.10e-041553831882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRC SCRG1 TRIM67

3.21e-041573839021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRC SCRG1 TRIM67

3.21e-04157383c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PAMR1 PLAC8 NLK

3.40e-0416038319105debef96ea0c267d6a1d332303ec668ae47e
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ABLIM2 ALG1L2 PLAC8

3.40e-04160383955acb023ce4ccfac5073c9d693db87db3856187
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 CSRP2

3.46e-04161383f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SPRY1 TRIM36 PLAC8

3.85e-0416738399db8871c62336bd215efb65e969783d2b6003b0
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRISPLD1 RNF182 CSRP2

3.92e-0416838332e4d82efaccf336d347e4063253c3635a3ec672
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRIM36 OTOGL RNF182

3.92e-04168383bfa1491e8d433933003778b274710d3a16d973cb
ToppCelldroplet-Fat-Scat|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 GRN PLAC8

4.06e-04170383de722bea7527d6ad11b69f8e9589638f52854beb
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYRIP SPRY1 CRISPLD1

4.06e-041703836c65ddb496030bb479ef346cc37a9d4dfa6b824f
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 CSRP2

4.06e-04170383af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 CSRP2

4.20e-04172383fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 CSRP2

4.20e-04172383745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB3 PAMR1 CRISPLD1

4.34e-04174383eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APBB3 PAMR1 CRISPLD1

4.34e-0417438332fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

HRC TRIM9 CSRP2

4.41e-04175383ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCRG1 P2RY11 TRIM9

4.56e-041773835357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 CSRP2

4.64e-041783830139b42494c1186390b12106dea7957e2b6717c2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

DIDO1 CRISPLD1 ANKRD27

4.64e-04178383edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SCRG1 FBLN7 CRISPLD1

4.64e-041783838591a40fced747ac16b3e8ebc7a22dfb3ad76da2
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SCRG1 FBLN7 CRISPLD1

4.64e-04178383c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SPRY1 P2RY11 PLAC8

4.64e-0417838371ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MYRIP TRIM67 TRIM9

4.72e-04179383e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM219 CRISPLD1 RNF182

4.72e-04179383ec331b1132f965581f851a3b29e62873c4140e6c
ToppCellMesenchymal_cells-Chondrocytes|Mesenchymal_cells / Lineage and Cell class

SCRG1 FBLN7 CRISPLD1

4.79e-041803836e399368430ef3afa9ce1ef0ed90f614ccef9987
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRG1 TRIM9 CRISPLD1

4.87e-041813833aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYRIP PLAC8 CSRP2

4.87e-0418138372c28baf4fd417ff4a7068603830d55074960144
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRG1 TRIM9 CRISPLD1

4.87e-04181383997ba1be2824b00d684f2163d0114656ed11fa53
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial-vein_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYRIP PLAC8 CSRP2

4.87e-041813832ac4d3e8987d5a009d7908d8787e18165826202a
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYRIP DIDO1 CRISPLD1

4.87e-041813834ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRG1 TRIM9 CRISPLD1

4.87e-04181383e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellfacs-Lung-3m-Endothelial-venous_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYRIP PLAC8 CSRP2

4.87e-041813832628c7ac345eaaeecf8e34617e81948925962cb9
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-DC-cDC2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCUBE2 ALG1L2 PLAC8

4.95e-041823831d37c486173cc4629842893ddd5033987c04086f
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)|Cerebellum / BrainAtlas - Mouse McCarroll V32

HRC RAD18 DEFB124

4.95e-04182383da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

HRC OTOGL CSRP2

4.95e-0418238346c213597445b1f4f09dc367f27702d24b201daf
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 CSRP2

4.95e-04182383345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCellCerebellum-Endothelial-MURAL|Cerebellum / BrainAtlas - Mouse McCarroll V32

HRC RAD18 DEFB124

4.95e-04182383b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-DC-cDC2-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCUBE2 ALG1L2 PLAC8

4.95e-04182383aef67bdc6937b315522d39959e26c9b0acf7ab52
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-DC|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCUBE2 ALG1L2 PLAC8

4.95e-04182383087c9f88daf08f5d688b728c2386f91f210d2255
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HRC SPRY1 PAMR1

4.95e-04182383fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMYD4 SPRY1 CSRP2

5.03e-04183383262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMYD4 SPRY1 CSRP2

5.03e-04183383c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYRIP CRISPLD1 CSRP2

5.03e-04183383fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

MYRIP CRISPLD1 CSRP2

5.11e-04184383b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HRC SPRY1 OTOGL

5.11e-04184383603faafb7b289a3c0242c84fc800c050c8a092ea
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

SCRG1 FBLN7 CRISPLD1

5.11e-041843831e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HRC SPRY1 OTOGL

5.11e-04184383c350504bfe0ec31cd2fc2199de9b5fff151a8c5e
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 PLAC8 CSRP2

5.19e-041853833cd0686a14e734a0f243070ab939adcb4c454478
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 PLAC8 CSRP2

5.19e-0418538300258f458cbf6d36449db95528a6b5038d731d2d
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 PLAC8 CSRP2

5.19e-04185383a94694e226856bc5b168464f52d76004145717a5
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FBLN7 TRIM9 CRISPLD1

5.19e-041853838ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

SPRY1 TRIM67 PAMR1

5.19e-04185383427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FBLN7 TRIM9 CRISPLD1

5.19e-04185383b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPRY1 SCUBE2 CRISPLD1

5.27e-041863834e983de6d2515082f9e555f4f949cec84281c140
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SCRG1 FBLN7 PAMR1

5.27e-0418638380a0a42ca8585cdb1dda57a18c254316a126ee64
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SMYD5 SPRED2 ANKRD27

5.27e-04186383927723ad579bbd9947ff525bd501e222d3fa9289
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRC SPRY1 CSRP2

5.27e-041863836568358812f0ca4e0161a1a1b29682fbced35c79
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYRIP ABLIM2 CRISPLD1

5.27e-04186383c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HRC DEFB124 CSRP2

5.27e-041863830c477016c1b539b3086a8066c3c6443f08c222a3
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYRIP CRISPLD1 PLAC8

5.36e-0418738366ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellControl-Endothelial-VE_Peribronchial|Endothelial / Disease state, Lineage and Cell class

MYRIP SPRY1 NLK

5.36e-041873835429ae85942b8ec3895cceb63c663de3c24ca064
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HRC FBLN7 TRIM67

5.44e-0418838372cbfe9dc0583dbeafa6cb0945fa370d0c808284
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

FBLN7 TRIM9 CRISPLD1

5.44e-041883837b1e3f8a941eaa68e89c562129a92314642eec66
DiseaseOpitz GBBB syndrome (implicated_via_orthology)

TRIM67 TRIM36 TRIM9

2.54e-086333DOID:0080697 (implicated_via_orthology)
Diseasecolon carcinoma

ODF1 CRISPLD1

3.88e-0426332EFO_1001950
Diseaseclostridium difficile infection

FBLN7 TRIM36 ANKRD27

5.58e-04144333EFO_0009130
Disease3-hydroxy-1-methylpropylmercapturic acid measurement

MYRIP PNPT1 RAD18 TRIM36

6.20e-04352334EFO_0007015
Diseaseskin aging measurement

PNPT1 SPRY1 MC1R

1.08e-03181333EFO_0008006
Diseasecolorectal health

RAD18 SCUBE2 PAMR1

1.46e-03201333EFO_0008460
Diseasesystemic lupus erythematosus

NADSYN1 SPRED2 ANKRD27 RNF182 PLAC8

1.82e-03799335MONDO_0007915
Diseaseage at menopause

DIDO1 RAD18 ODF1

4.61e-03302333EFO_0004704
Diseasediffusing capacity of the lung for carbon monoxide

TRIM67 ABLIM2

5.18e-0396332EFO_0009369
Diseasehandedness

TRIM36 PAMR1

6.28e-03106332EFO_0009902
Diseaseexecutive function measurement

SMYD4 TRIM36 CRISPLD1

8.44e-03376333EFO_0009332

Protein segments in the cluster

PeptideGeneStartEntry
MFRCCLPACAVNFKC

ALG1L2

166

C9J202
PMPQASCCEDRVHCC

GRN

151

P28799
CPACMTTLCLDCQRH

EAPP

181

Q56P03
YHPSCALCVRCGQMF

ABLIM2

231

Q6H8Q1
MIIPQCSHNYCSLCI

RAD18

36

Q9NS91
NRNLHSPMYCFICCL

MC1R

66

Q01726
TVQKMCHPLCFCDDC

ANKRD27

426

Q96NW4
VCIYTSSCVCACVHM

OVOS1

11

Q6IE37
MHACVNTPGSYRCTC

FBLN7

241

Q53RD9
YMAAVPSLGCCCRHC

P2RY11

321

Q96G91
MSYDRYAAICCPLHC

OR14K1

116

Q8NGZ2
YAAICCPLHCEAVMS

OR14K1

121

Q8NGZ2
CKMCRPRAYIFSDCH

EEF2KMT

176

Q96G04
RLRYHTCMCKCCFST

NLK

431

Q9UBE8
LCDLYMHPYCCCDLH

ODF1

36

Q14990
VMRQSRPHCCACYEA

PRICKLE3

291

O43900
DSCMLKCHVFCCDVP

APBB3

221

O95704
DGRSFHRCCFLCMVC

CSRP2

26

Q16527
HRCCFLCMVCRKNLD

CSRP2

31

Q16527
ACMCVCVHVCACVYV

C18orf15

131

Q96N68
CVHVCACVYVCMCVL

C18orf15

136

Q96N68
ACVYVCMCVLVCMCA

C18orf15

141

Q96N68
VCMCACACMRAHRYF

C18orf15

151

Q96N68
SHCPRVYCPRNCMQA

CRISPLD1

411

Q9H336
QETYMHLCPDASLCC

DEFB124

41

Q8NES8
CICRQPHNNRFMICC

DIDO1

271

Q9BTC0
HTCVNVMGSYECCCK

SCUBE2

141

Q9NQ36
PCYTCVCRRGMFNCT

OTOGL

926

Q3ZCN5
MCRECCEYDQIECVC

PAMR1

41

Q6UXH9
NMYCELCRRPVCHLC

TRIM36

221

Q9NQ86
DCACPACQTEAHRMA

SMYD4

596

Q8IYR2
FCQCVCHEFLDCMAP

RNF182

231

Q8N6D2
EMICYCNFSELLCCP

SCRG1

66

O75711
CQHCQFCYLCPLVCE

HRC

656

P23327
MAACRYCCSCLRLRP

PNPT1

1

Q8TCS8
CDVLYCSACQLKCHP

TRIM67

226

Q6ZTA4
MCCYLPLRACYHCGV

SPRED2

391

Q7Z698
CSCSQSHCCSRYLCM

SPRY1

246

O43609
MCEQCDVFYCDPCRL

TRIM9

181

Q9C026
CGLLCCVTAMCFHPR

TMEM219

216

Q86XT9
DDYMATLCCPHCTLC

PLAC8

86

Q9NZF1
CPHCQVMYCSAECRL

SMYD5

111

Q6GMV2
ACLIYSMCCQVCEAV

NADSYN1

366

Q6IA69
HQQFVEHCCMRCCSP

MYRIP

56

Q8NFW9
EHCCMRCCSPFTFLV

MYRIP

61

Q8NFW9