Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 MYO19 DNAH7 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11 DNAH5 DNAH8

3.13e-0744113515GO:0016887
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11

7.59e-071091358GO:0042626
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 MYO19 DNAH7 DICER1 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11 DNAH5 DNAH8 HELLS

8.76e-0761413517GO:0140657
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ABCB11

9.41e-07491356GO:0140359
GeneOntologyMolecularFunctionsphingolipid floppase activity

ABCA1 ABCA2 ABCB1

1.20e-0641353GO:0046623
GeneOntologyMolecularFunctionfloppase activity

ABCA1 ABCA2 ABCB1 ATP8A1

3.41e-06161354GO:0140328
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 ENPP2 MYO19 BMS1 RGS11 DNAH7 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11 DNAH5 DNAH8 RHOF

3.76e-0683913519GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 ENPP2 MYO19 BMS1 RGS11 DNAH7 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11 DNAH5 DNAH8 RHOF

3.83e-0684013519GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 ENPP2 MYO19 BMS1 RGS11 DNAH7 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11 DNAH5 DNAH8 RHOF

3.83e-0684013519GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 MYO19 BMS1 RGS11 DNAH7 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11 DNAH5 DNAH8 RHOF

4.91e-0677513518GO:0017111
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH7 DNAH5 DNAH8

5.68e-06181354GO:0008569
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 ABCB11

2.88e-051781358GO:0015399
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH7 DNAH5 DNAH8

3.61e-05281354GO:0051959
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ABCA2 ABCB1 ATP8A1

3.61e-05281354GO:0140326
GeneOntologyMolecularFunctionlipid transporter activity

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ATP8A1 ABCB11 SLC5A8

5.71e-051961358GO:0005319
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA1 SLC29A3 ABCA2 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 SLC17A7 ABCB11 SLC5A8 SLC17A6

9.77e-0547713512GO:0022804
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH7 DNAH5 DNAH8

1.11e-04371354GO:0045505
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCA8 ABCB1 ABCB11

1.30e-04151353GO:0008559
GeneOntologyMolecularFunctionceramide floppase activity

ABCA2 ABCB1

1.36e-0431352GO:0099038
GeneOntologyMolecularFunctionL-glutamate uniporter activity

SLC17A7 SLC17A6

1.36e-0431352GO:0140788
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCA1 ABCA2 ABCB1

3.17e-04201353GO:0046624
GeneOntologyMolecularFunctionneurotransmitter transmembrane transporter activity

SLC29A3 SLC17A7 SLC17A6

3.68e-04211353GO:0005326
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA1 ABCA2 ABCB1 ATP8A1

3.90e-04511354GO:0140303
GeneOntologyMolecularFunctionmembrane potential driven uniporter activity

SLC17A7 SLC17A6

4.48e-0451352GO:0022810
GeneOntologyMolecularFunctionG protein-coupled opioid receptor activity

OPRD1 OPRK1

9.32e-0471352GO:0004985
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCA1 ABCB1

1.24e-0381352GO:0090554
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 MYO19 DNAH7 DNAH5 DNAH8

1.25e-031181355GO:0003774
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH7 DNAH5 DNAH8

1.30e-03701354GO:0003777
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCA8 ABCB1 ABCB11

1.55e-03341353GO:0042910
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ABCA1 ATP8A1

1.58e-0391352GO:0090556
GeneOntologyMolecularFunctionreceptor serine/threonine kinase binding

OPRD1 OPRK1 PYCARD

1.69e-03351353GO:0033612
GeneOntologyMolecularFunctionuniporter activity

SLC17A7 SLC17A6

1.97e-03101352GO:0015292
GeneOntologyMolecularFunctiontransmembrane transporter activity

CHRNA6 ABCA1 SLC29A3 ABCA2 PIEZO1 SLC19A2 ABCA9 ABCA8 ABCB1 ATP6V1H ATP8A1 SCN1A SLC17A7 ABCB11 KCNS1 SLC5A8 SLC17A6

2.55e-03118013517GO:0022857
GeneOntologyMolecularFunctionmyosin binding

NPHS1 MYO19 PYCARD USH2A

2.65e-03851354GO:0017022
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC17A7 SLC17A6

2.86e-03121352GO:0005436
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC19A2 ABCB1 SLC17A7 ABCB11 SLC5A8 SLC17A6

2.87e-032071356GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC19A2 ABCB1 SLC17A7 ABCB11 SLC5A8 SLC17A6

2.94e-032081356GO:0005342
GeneOntologyBiologicalProcesssphingolipid translocation

ABCA1 ABCA2 ABCB1

2.84e-0651373GO:0099039
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 DNAH7 DNAH5 DNAH8

2.12e-05251394GO:0005858
GeneOntologyCellularComponentexocytic vesicle membrane

DMXL2 DYSF OPRD1 OPRK1 ATP6V1H ATP8A1 SLC17A7 SLC17A6

2.68e-051791398GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

DMXL2 DYSF OPRD1 OPRK1 ATP6V1H ATP8A1 SLC17A7 SLC17A6

2.68e-051791398GO:0030672
GeneOntologyCellularComponenttransport vesicle membrane

SEC16B DMXL2 DYSF OPRD1 OPRK1 ATP6V1H ATP8A1 SLC17A7 SLC17A6

1.54e-042931399GO:0030658
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH7 DNAH5 DNAH8

4.58e-04541394GO:0030286
GeneOntologyCellularComponentsecretory vesicle

DMXL2 SPATA31A3 SPATA31A7 ANXA7 IDH1 DYSF SPATA31A5 OPRD1 OPRK1 ATP6V1H ATP8A1 SPATA31A1 CADPS PYCARD SLC17A7 CDA TSSK4 RHOF SLC17A6

6.02e-04124613919GO:0099503
GeneOntologyCellularComponentcollagen type IV trimer

COL4A2 COL4A3

6.47e-0461392GO:0005587
GeneOntologyCellularComponentsynaptic vesicle

DMXL2 DYSF OPRD1 OPRK1 ATP6V1H ATP8A1 SLC17A7 SLC17A6

9.11e-043001398GO:0008021
GeneOntologyCellularComponent9+2 motile cilium

DNAH3 CFAP251 DNAH7 PCDH11X DNAH5 TSSK4 DNAH8

1.09e-032381397GO:0097729
GeneOntologyCellularComponentbasement membrane collagen trimer

COL4A2 COL4A3

1.20e-0381392GO:0098651
GeneOntologyCellularComponentnetwork-forming collagen trimer

COL4A2 COL4A3

1.20e-0381392GO:0098642
GeneOntologyCellularComponentcollagen network

COL4A2 COL4A3

1.20e-0381392GO:0098645
GeneOntologyCellularComponentbasement membrane

NPHS1 COL4A2 COL4A3 ADAMTS1 USH2A

1.35e-031221395GO:0005604
GeneOntologyCellularComponentexocytic vesicle

DMXL2 DYSF OPRD1 OPRK1 ATP6V1H ATP8A1 SLC17A7 SLC17A6

1.37e-033201398GO:0070382
GeneOntologyCellularComponentspine apparatus

SYNPO OPRD1

1.53e-0391392GO:0097444
GeneOntologyCellularComponentchromaffin granule membrane

ANXA7 ATP8A1

1.53e-0391392GO:0042584
GeneOntologyCellularComponentintercellular canaliculus

ABCB1 ABCB11

1.53e-0391392GO:0046581
GeneOntologyCellularComponentneuronal dense core vesicle

DMXL2 OPRD1 CADPS

1.75e-03361393GO:0098992
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH7

1.91e-03101392GO:0036156
GeneOntologyCellularComponentpresynapse

CHRNA6 DMXL2 NLGN1 DYSF OPRD1 OPRK1 ATP6V1H ATP8A1 CADPS SCN1A RIMS4 SLC17A7 USH2A SLC17A6

2.36e-0388613914GO:0098793
MousePhenodecreased cell proliferation

FAM120B PDGFRB DOCK8 ENPP2 EZH2 BHLHE40 DICER1 LEPR UBE2O SPPL2A PER2 CD19 RPTOR BTK TNRC6A PRKCQ LTB4R CDK2 HELLS

3.89e-0673910919MP:0000352
DomainAAA

DNAH3 ABCA1 ABCA2 VWA8 DNAH7 ABCA9 ABCA8 ABCB1 ABCB11 DNAH5 DNAH8

7.70e-0914413511SM00382
DomainAAA+_ATPase

DNAH3 ABCA1 ABCA2 VWA8 DNAH7 ABCA9 ABCA8 ABCB1 ABCB11 DNAH5 DNAH8

7.70e-0914413511IPR003593
DomainABC_tran

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ABCB11

1.22e-06481356PF00005
DomainABC_TRANSPORTER_2

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ABCB11

1.22e-06481356PS50893
DomainABC_A

ABCA1 ABCA2 ABCA9 ABCA8

1.24e-06121354IPR026082
DomainABC_TRANSPORTER_1

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ABCB11

1.38e-06491356PS00211
DomainABC_transporter-like

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ABCB11

1.56e-06501356IPR003439
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH7 DNAH5 DNAH8

2.47e-06141354IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH7 DNAH5 DNAH8

2.47e-06141354IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH7 DNAH5 DNAH8

2.47e-06141354IPR013602
DomainDHC_N2

DNAH3 DNAH7 DNAH5 DNAH8

2.47e-06141354PF08393
DomainATPase_dyneun-rel_AAA

DNAH3 VWA8 DNAH5 DNAH8

2.47e-06141354IPR011704
DomainMT

DNAH3 DNAH7 DNAH5 DNAH8

2.47e-06141354PF12777
DomainAAA_8

DNAH3 DNAH7 DNAH5 DNAH8

2.47e-06141354PF12780
DomainAAA_5

DNAH3 VWA8 DNAH5 DNAH8

2.47e-06141354PF07728
DomainDHC_fam

DNAH3 DNAH7 DNAH5 DNAH8

3.35e-06151354IPR026983
DomainDynein_heavy

DNAH3 DNAH7 DNAH5 DNAH8

3.35e-06151354PF03028
DomainDynein_heavy_dom

DNAH3 DNAH7 DNAH5 DNAH8

3.35e-06151354IPR004273
Domain-

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 MYO19 BMS1 DNAH7 DICER1 ABCA9 ABCA8 ABCB1 TRANK1 ABCB11 DNAH5 DNAH8 RHOF HELLS

7.22e-06746135183.40.50.300
DomainP-loop_NTPase

DNAH3 ABCA1 ABCA2 VWA8 RTEL1 MYO19 BMS1 DNAH7 DICER1 ABCA9 ABCA8 ABCB1 TRANK1 ABCB11 DNAH5 DNAH8 RHOF HELLS

3.99e-0584813518IPR027417
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

7.75e-05121353PF15371
DomainDUF4599

SPATA31A3 SPATA31A7 SPATA31A5

7.75e-05121353IPR027970
DomainABC_transporter_CS

ABCA1 ABCA2 ABCB1 ABCB11

2.36e-04421354IPR017871
DomainOpioid_rcpt

OPRD1 OPRK1

3.08e-0441352IPR001418
DomainC4

COL4A2 COL4A3

7.63e-0461352SM00111
DomainCollagen_VI_NC

COL4A2 COL4A3

7.63e-0461352IPR001442
DomainNC1_IV

COL4A2 COL4A3

7.63e-0461352PS51403
Domain-

COL4A2 COL4A3

7.63e-04613522.170.240.10
DomainC4

COL4A2 COL4A3

7.63e-0461352PF01413
DomainDHC_N1

DNAH5 DNAH8

1.41e-0381352PF08385
DomainDynein_heavy_dom-1

DNAH5 DNAH8

1.41e-0381352IPR013594
PathwayKEGG_ABC_TRANSPORTERS

ABCA1 ABCA2 ABCA9 ABCA8 ABCB1 ABCB11

7.40e-07441036M11911
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH7 DNAH5 DNAH8

4.15e-05271034M47755
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A7 SLC5A8 SLC17A6

7.94e-05121033M27350
PathwayREACTOME_ORGANIC_ANION_TRANSPORTERS

SLC17A7 SLC5A8 SLC17A6

7.94e-05121033MM15087
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1

3.64e-096139420850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1

3.64e-096139425930072
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ABCA2 SZT2 VWA8 PIEZO1 SUN1 BMS1 SYNPO DICER1 UBE2O TRANK1 MAST4 SMG7 RPTOR TNRC6A

3.09e-085291391414621295
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH3 DNAH7 DNAH5 DNAH8

2.37e-071413949373155
Pubmed

Large-scale identification of genes implicated in kidney glomerulus development and function.

NPHS1 COL4A2 COL4A3 PDGFRB SYNPO

2.40e-0734139516498405
Pubmed

Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.

ABCA1 ABCA9 ABCA8

6.21e-075139312532264
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH3 DNAH5 DNAH8

2.16e-06713939256245
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A3 SPATA31A7 SPATA31A5 SPATA31A1

2.44e-0624139432212159
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

CHRNA6 NLGN1 LEPR OPRD1 OPRK1 ABCB1 SLC17A7 NRG3 SLC17A6

3.61e-06300139919086053
Pubmed

Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.

ABCA2 ABCA8 ABCB1

5.16e-069139321707071
Pubmed

Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy.

NPHS1 COL4A3 SYNPO

5.16e-069139335499085
Pubmed

Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure.

NPHS1 PDGFRB SYNPO

7.34e-0610139322840396
Pubmed

Diversification of stem cell molecular repertoire by alternative splicing.

BRIX1 DOCK8 PYCARD BTK

1.16e-0535139416183747
Pubmed

Vesicular glutamate transporters 1 and 2 target to functionally distinct synaptic release sites.

SLC17A7 SLC17A6

1.59e-052139215118123
Pubmed

ABCB11 and ABCB1 gene polymorphisms impact on telaprevir pharmacokinetic at one month of therapy.

ABCB1 ABCB11

1.59e-052139225661339
Pubmed

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.

ABCA1 ABCA2

1.59e-052139215649702
Pubmed

Transiently increased colocalization of vesicular glutamate transporters 1 and 2 at single axon terminals during postnatal development of mouse neocortex: a quantitative analysis with correlation coefficient.

SLC17A7 SLC17A6

1.59e-052139218028110
Pubmed

Beta-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment.

ABCA1 SCN1A

1.59e-052139217322896
Pubmed

μ-Opioid receptor antibody reveals tissue-dependent specific staining and increased neuronal μ-receptor immunoreactivity at the injured nerve trunk in mice.

OPRD1 OPRK1

1.59e-052139224278116
Pubmed

ABC transporters: from microorganisms to man.

ABCA1 ABCA2

1.59e-05213921282354
Pubmed

Phosphorylation of CDK2 at threonine 160 regulates meiotic pachytene and diplotene progression in mice.

SUN1 CDK2

1.59e-052139224797635
Pubmed

Modulation of expressivity in PDGFRB-related infantile myofibromatosis: a role for PTPRG?

PDGFRB PTPRG

1.59e-052139225158255
Pubmed

Altered vesicular glutamate transporter expression in the anterior cingulate cortex in schizophrenia.

SLC17A7 SLC17A6

1.59e-052139218155679
Pubmed

Histone Methyltransferase Enhancer of Zeste Homolog 2-Mediated ABCA1 Promoter DNA Methylation Contributes to the Progression of Atherosclerosis.

ABCA1 EZH2

1.59e-052139227295295
Pubmed

Haploinsufficiency of VGluT1 but not VGluT2 impairs extinction of spatial preference and response suppression.

SLC17A7 SLC17A6

1.59e-052139223396167
Pubmed

Vesicular glutamate transporter VGLUT1 has a role in hippocampal long-term potentiation and spatial reversal learning.

SLC17A7 SLC17A6

1.59e-052139219574394
Pubmed

Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter.

SLC17A7 SLC17A6

1.59e-052139210820226
Pubmed

Disruption of VGLUT1 in Cholinergic Medial Habenula Projections Increases Nicotine Self-Administration.

SLC17A7 SLC17A6

1.59e-052139234876472
Pubmed

Interplay between VGLUT isoforms and endophilin A1 regulates neurotransmitter release and short-term plasticity.

SLC17A7 SLC17A6

1.59e-052139221435559
Pubmed

Variants in CDA and ABCB1 are predictors of capecitabine-related adverse reactions in colorectal cancer.

ABCB1 CDA

1.59e-052139225691056
Pubmed

The seventh transmembrane domains of the delta and kappa opioid receptors have different accessibility patterns and interhelical interactions.

OPRD1 OPRK1

1.59e-052139216331961
Pubmed

Overcoming ABCB1-mediated multidrug resistance by transcription factor BHLHE40.

BHLHE40 ABCB1

1.59e-052139236931039
Pubmed

Identification of kappa- and delta-opioid receptor transcripts in immune cells.

OPRD1 OPRK1

1.59e-05213927649271
Pubmed

miRNAs are required for generating a time delay critical for the circadian oscillator.

DICER1 PER2

1.59e-052139224094851
Pubmed

Differential sorting of the vesicular glutamate transporter 1 into a defined vesicular pool is regulated by light signaling involving the clock gene Period2.

PER2 SLC17A7

1.59e-052139216595674
Pubmed

Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer disease.

SLC17A7 SLC17A6

1.59e-052139217531353
Pubmed

Interference with endogenous EZH2 reverses the chemotherapy drug resistance in cervical cancer cells partly by up-regulating Dicer expression.

EZH2 DICER1

1.59e-052139226631032
Pubmed

Two distinct GUCY2C circuits with PMV (hypothalamic) and SN/VTA (midbrain) origin.

LEPR GUCY2C

1.59e-052139231485718
Pubmed

ABCA1 Is Coordinated with ABCB1 in the Arsenic-Resistance of Human Cells.

ABCA1 ABCB1

1.59e-052139229951962
Pubmed

Association of the ATP-binding cassette transporter A1 R230C variant with early-onset type 2 diabetes in a Mexican population.

ABCA1 ABCB1

1.59e-052139218003760
Pubmed

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.

EZH2 CD19

1.59e-052139212496962
Pubmed

Impairment of VGLUT2 but not VGLUT1 signaling reduces neuropathy-induced hypersensitivity.

SLC17A7 SLC17A6

1.59e-052139219171494
Pubmed

MicroRNAs prevent the generation of autoreactive antibodies.

DICER1 CD19

1.59e-052139221093320
Pubmed

mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia.

CD19 RPTOR

1.59e-052139237775560
Pubmed

Phosphorylation of CD19 Y484 and Y515, and linked activation of phosphatidylinositol 3-kinase, are required for B cell antigen receptor-mediated activation of Bruton's tyrosine kinase.

CD19 BTK

1.59e-052139210201980
Pubmed

Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity.

ENPP2 LEPR

1.59e-052139212642576
Pubmed

Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.

OPRD1 OPRK1

1.59e-05213928393575
Pubmed

Malaria in pregnancy regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 efflux transporters in the Mouse Visceral Yolk Sac.

ABCA1 ABCB1

1.59e-052139232779889
Pubmed

Regulations of opioid dependence by opioid receptor types.

OPRD1 OPRK1

1.59e-052139211316510
Pubmed

[Pharmacogenetic criteria of drug-resistant epilepsy].

ABCB1 SCN1A

1.59e-052139223786015
Pubmed

Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum.

SLC17A7 SLC17A6

1.59e-052139221800314
Pubmed

LncRNA LINC00968 accelerates the proliferation and fibrosis of diabetic nephropathy by epigenetically repressing p21 via recruiting EZH2.

EZH2 LEPR

1.59e-052139230197001
Pubmed

The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk.

OPRD1 OPRK1

1.59e-052139217622222
Pubmed

BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.

EZH2 CD19

1.59e-052139235226736
Pubmed

Chromatin changes in dicer-deficient mouse embryonic stem cells in response to retinoic acid induced differentiation.

EZH2 DICER1

1.59e-052139224040281
Pubmed

Expression of the vesicular glutamate transporters-1 and -2 in adult mouse dorsal root ganglia and spinal cord and their regulation by nerve injury.

SLC17A7 SLC17A6

1.59e-052139217577523
Pubmed

ABCA1/ABCB1 Ratio Determines Chemo- and Immune-Sensitivity in Human Osteosarcoma.

ABCA1 ABCB1

1.59e-052139232155954
Pubmed

Cloning, characterization and tissue distribution of the rat ATP-binding cassette (ABC) transporter ABC2/ABCA2.

ABCA1 ABCA2

1.59e-052139210970803
Pubmed

Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia.

SLC17A7 SLC17A6

1.59e-052139219839996
Pubmed

Compensatory role of P-glycoproteins in knockout mice lacking the bile salt export pump.

ABCB1 ABCB11

1.59e-052139219650158
Pubmed

Vesicular glutamate transporters VGLUT1 and VGLUT2 in the developing mouse barrel cortex.

SLC17A7 SLC17A6

1.59e-052139217289331
Pubmed

Dock8 regulates BCR signaling and activation of memory B cells via WASP and CD19.

DOCK8 CD19

1.59e-052139229472447
Pubmed

Vesicular glutamate transporters define two sets of glutamatergic afferents to the somatosensory thalamus and two thalamocortical projections in the mouse.

SLC17A7 SLC17A6

1.59e-052139218181146
Pubmed

ABC proteins protect the human body and maintain optimal health.

ABCA1 ABCB1

1.59e-052139221389634
Pubmed

Cloning of two novel ABC transporters mapping on human chromosome 9.

ABCA1 ABCA2

1.59e-05213928088782
Pubmed

Bifunctional lipocalin ameliorates murine immune complex-induced acute lung injury.

C5 LTB4R

1.59e-052139223625922
Pubmed

Anti-nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist.

OPRD1 OPRK1

1.59e-052139224923251
Pubmed

Interactive effect between ATPase-related genes and early-life tobacco smoke exposure on bronchial hyper-responsiveness detected in asthma-ascertained families.

ABCA1 ATP8A1

1.59e-052139230282721
Pubmed

G-protein-coupled receptor heterodimerization modulates receptor function.

OPRD1 OPRK1

1.59e-052139210385123
Pubmed

Altered vesicular glutamate transporter distributions in the mouse cochlear nucleus following cochlear insult.

SLC17A7 SLC17A6

1.59e-052139226705736
Pubmed

Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia.

NPHS1 SYNPO

1.59e-052139217255128
Pubmed

Role of kappa- and delta-opioid receptors in the antinociceptive effect of oxytocin in formalin-induced pain response in mice.

OPRD1 OPRK1

1.59e-052139216712978
Pubmed

Postnatal changes of vesicular glutamate transporter (VGluT)1 and VGluT2 immunoreactivities and their colocalization in the mouse forebrain.

SLC17A7 SLC17A6

1.59e-052139216217795
Pubmed

Salmonella Promotes Its Own Survival in B Cells by Inhibiting Autophagy.

CD19 RPTOR

1.59e-052139235805144
Pubmed

MOR is not enough: identification of novel mu-opioid receptor interacting proteins using traditional and modified membrane yeast two-hybrid screens.

DOK5 OPRD1 OPRK1

2.74e-0515139323840749
Pubmed

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

NLGN1 SLC17A7 SLC17A6

2.74e-0515139318227507
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PDGFRB LEPR PTPRG ALK

3.81e-0547139419167335
Pubmed

Vesicular glutamate transporters use flexible anion and cation binding sites for efficient accumulation of neurotransmitter.

SLC17A7 SLC17A6

4.75e-053139225433636
Pubmed

Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13.

COL4A2 COL4A3

4.75e-05313923025878
Pubmed

Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2.

EZH2 CDK2

4.75e-053139220935635
Pubmed

Quantitative autoradiography of mu-,delta- and kappa1 opioid receptors in kappa-opioid receptor knockout mice.

OPRD1 OPRK1

4.75e-053139210082819
Pubmed

VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context.

PER2 SLC17A7

4.75e-053139229199069
Pubmed

Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers.

OPRD1 OPRK1

4.75e-053139218537939
Pubmed

Stem-like tumor cells confer drug resistant properties to mantle cell lymphoma.

ABCB1 CD19

4.75e-053139221599592
Pubmed

MicroRNA biogenesis is required for Myc-induced B-cell lymphoma development and survival.

DICER1 CD19

4.75e-053139220587524
Pubmed

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

TUB LEPR

4.75e-053139214679177
Pubmed

Cutting Edge: ROR1/CD19 Receptor Complex Promotes Growth of Mantle Cell Lymphoma Cells Independently of the B Cell Receptor-BTK Signaling Pathway.

CD19 BTK

4.75e-053139231534006
Pubmed

Opioid receptors: from binding sites to visible molecules in vivo.

OPRD1 OPRK1

4.75e-053139218718480
Pubmed

Angiotensin-converting enzyme 2 amplification limited to the circulation does not protect mice from development of diabetic nephropathy.

COL4A3 LEPR

4.75e-053139227927599
Pubmed

Docking and homology modeling explain inhibition of the human vesicular glutamate transporters.

SLC17A7 SLC17A6

4.75e-053139217660252
Pubmed

Sociability and synapse subtype-specific defects in mice lacking SRPX2, a language-associated gene.

SLC17A7 SLC17A6

4.75e-053139229920554
Pubmed

Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes.

LEPR LTB4R

4.75e-053139225628460
Pubmed

Heterodimerization of mu and delta opioid receptors: A role in opiate synergy.

OPRD1 OPRK1

4.75e-053139211069979
Pubmed

Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females*.

OPRD1 OPRK1

4.75e-053139219032295
Pubmed

The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice.

OPRD1 OPRK1

4.75e-053139215090050
Pubmed

Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression.

STRBP DICER1

4.75e-053139238280476
Pubmed

Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release.

LEPR SLC17A6

4.75e-053139226822087
Pubmed

Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling.

NPHS1 LEPR

4.75e-053139225448064
Pubmed

Executive function deficits and glutamatergic protein alterations in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

SLC17A7 SLC17A6

4.75e-053139226332770
Pubmed

Lack of evidence for vesicular glutamate transporter expression in mouse astrocytes.

SLC17A7 SLC17A6

4.75e-053139223467360
Cytoband8q11.2

OPRK1 ATP6V1H

5.44e-05413928q11.2
CytobandEnsembl 112 genes in cytogenetic band chr9q12

SPATA31A7 SPATA31A5

2.52e-0481392chr9q12
GeneFamilyATP binding cassette subfamily A

ABCA1 ABCA2 ABCA9 ABCA8

6.04e-0714924805
GeneFamilyDyneins, axonemal

DNAH3 DNAH7 DNAH5 DNAH8

1.42e-0617924536
GeneFamilyOpioid receptors

OPRD1 OPRK1

1.53e-044922245
GeneFamilyImmunoglobulin like domain containing

NPHS1 PDGFRB LEPR CD19 MYOM2 IL1RAP

4.56e-04193926594
GeneFamilyFibronectin type III domain containing

NPHS1 PTPRG MYOM2 USH2A TNXB

1.35e-03160925555
GeneFamilyATP binding cassette subfamily B

ABCB1 ABCB11

1.37e-0311922806
GeneFamilyDNA helicases

RTEL1 HELLS

3.31e-03179221167
CoexpressionAtlaskidney_adult_Podocyte_MafB_top-relative-expression-ranked_1000

NPHS1 COL4A3 FILIP1 ABCA2 VWA8 PDGFRB ANXA7 CYP27A1 SYNPO ABLIM3 ABCA9 FRY HOXC4 SPPL2A ATP8A1 MAST4 TBC1D1 MLLT11 MYOM2

9.53e-0783813119gudmap_kidney_adult_Podocyte_MafB_1000
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS1 PDGFRB SLC19A2 NLGN1 TUB ABCA9 ABCA8 PTPRG TNXB

1.13e-081951399ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 ADAMTS1 NLGN1 ABCA9 ABCA8 LEPR PTPRG TNXB

1.35e-0819913999c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

COL4A2 COL4A3 ADAMTS1 PDGFRB SLC19A2 ABCA9 LEPR MLLT11

1.47e-0718913983922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

DOK5 PDGFRB NLGN1 ABCA9 ABCA8 LEPR TNXB STEAP1

1.66e-071921398d21f0f577156f17c899b08871046a26b88aea011
ToppCellVE-naiveBc-|VE / Condition, Cell_class and T cell subcluster

COL4A3 STRBP SYNPO CD19 GUCY2C CADPS BTK DNAH8

1.66e-071921398bca2aec4811627225fccd92abe2f3b1ba729c9ce
ToppCellVE-naiveBc|VE / Condition, Cell_class and T cell subcluster

COL4A3 STRBP SYNPO CD19 GUCY2C CADPS BTK DNAH8

1.66e-07192139887cdda9a170f6f2fa56d0ed1d3fd2f93bfe09aa1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 ADAMTS1 PDGFRB SLC19A2 NLGN1 ABCA9 ABCA8 TNXB

1.73e-071931398261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellLV-14._Fibroblast_III|LV / Chamber and Cluster_Paper

COL4A2 COL4A3 ADAMTS1 PDGFRB SLC19A2 ABCA9 LEPR MLLT11

1.80e-071941398927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell5'-Adult-Appendix-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 FILIP1 ADAMTS1 PDGFRB SLC19A2 ABCA9 ABCA8 PTPRG

2.02e-071971398b11a5d909942a4299cbc0b27332b1a3f66f3bccd
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

COL4A2 ADAMTS1 PDGFRB ABLIM3 ABCA9 ABCA8 PTPRG TNXB

2.18e-0719913984bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL4A2 COL4A3 ABCA1 PIEZO1 SYNPO ABCA8 WWC2 RHOF

2.18e-0719913985a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 COL4A3 ADAMTS1 NLGN1 ABCA9 ABCA8 PTPRG TNXB

2.18e-0719913983835452e4848d7f7dd8651c17b746b271ef39688
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

COL4A2 ABLIM3 ABCA9 ABCA8 ABCB1 FRY MAST4 PTPRG

2.27e-072001398032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PDGFRB SLC19A2 NLGN1 ABCA9 ABCA8 LEPR TNXB

2.27e-072001398ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

COL4A2 ABLIM3 ABCA9 ABCA8 ABCB1 FRY MAST4 PTPRG

2.27e-07200139868fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

COL4A2 ABLIM3 ABCA9 ABCA8 ABCB1 FRY MAST4 PTPRG

2.27e-072001398376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

COL4A2 ABLIM3 ABCA9 ABCA8 ABCB1 FRY MAST4 PTPRG

2.27e-0720013987fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

COL4A2 ABLIM3 ABCA9 ABCA8 ABCB1 FRY MAST4 PTPRG

2.27e-072001398878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

COL4A2 ABLIM3 ABCA9 ABCA8 ABCB1 FRY MAST4 PTPRG

2.27e-0720013987136936d05ab344a560cf159684c881063b5430d
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 ABCA1 PDGFRB ABCA9 ABCA8 LEPR PTPRG TNXB

2.27e-0720013980c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL4A2 ABCA1 ADAMTS1 ABCA8 PTPRG PCDH11X ALK

1.27e-061741397f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A2 FILIP1 ADAMTS1 PDGFRB FRY PTPRG TBC1D1

1.32e-0617513971125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellnormal-na-Lymphocytic_B-B_mem-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

COL4A3 STRBP SYNPO CD19 CADPS BTK DNAH8

1.72e-061821397ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCellNS-critical-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL4A2 ADAMTS1 ENPP2 NLGN1 ABCA9 ABCA8 NRG3

1.72e-061821397dd1c59babf7211362452e3e264009d70004d99f6
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

COL4A2 SEC16B DOCK8 NLGN1 MAST4 SLC5A8 ACMSD

1.85e-06184139751ed1ebfdef45149541917c66cbacad87072e51f
ToppCellCOVID-19-Fibroblasts-Adventitial_FB|COVID-19 / group, cell type (main and fine annotations)

PDGFRB NLGN1 ABCA9 ABCA8 LEPR PTPRG TNXB

1.92e-061851397a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

FILIP1 EZH2 ABCA9 ABCA8 LEPR CDA TNXB

1.99e-0618613976259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

COL4A2 COL4A3 ABCA1 SYNPO ABCA8 WWC2 NRG3

2.06e-0618713973a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

ENPP2 NLGN1 ABCB1 MAST4 SLC5A8 ACMSD HAO2

2.06e-061871397acd305475f3609800af0d7bc68d83ef41228080b
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

DOK5 ADAMTS1 NLGN1 ABCA9 ABCA8 LEPR TNXB

2.13e-061881397706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellMulticiliated|World / shred by cell class for nasal brushing

FILIP1 DNAH3 CFAP251 HOATZ GPR162 DNAH7 DNAH5

2.21e-06189139734b110aef839376228c5a403a6b5047a945f472b
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

DOK5 PDGFRB NLGN1 ABCA9 ABCA8 TNXB STEAP1

2.29e-0619013977dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SEC16B ABCA1 CYP27A1 CPS1 ABCB11 NRG3 IL1RAP

2.29e-061901397b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A3 STRBP EZH2 GTF3C4 FBXO10 CD19 DNAH8

2.29e-0619013970db545a4cba7534bad2693e0d565cde7dbc7a586
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC2 FILIP1 ABCA1 ENPP2 CADPS FAM151A USH2A

2.45e-0619213975b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LIPK OPRK1 GUCY2C FAM151A CYP4F22 USH2A DNAH8

2.54e-061931397315840bc48899f3a36d57b19197509de19716e3d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS1 NLGN1 DNAH7 PER2 ACMSD NRG3 DNAH5

2.54e-061931397ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUB TRANK1 CADPS SLC17A7 KCNS1 NRG3 SLC17A6

2.54e-061931397461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TUB TRANK1 CADPS SLC17A7 KCNS1 NRG3 SLC17A6

2.54e-0619313970dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 CFAP251 PDGFRB ABCA9 ABCA8 TRANK1 TNXB

2.62e-06194139781713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A3 FILIP1 TMTC2 WWC2 ATP8A1 MAST4 SCN1A

2.62e-06194139753f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FILIP1 CFAP251 PDGFRB ABCA9 ABCA8 TRANK1 TNXB

2.62e-061941397627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellCOPD-Stromal-Myofibroblast|COPD / Disease state, Lineage and Cell class

COL4A2 FILIP1 ADAMTS1 PDGFRB ABCA8 PTPRG STEAP1

2.81e-061961397af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 CFAP251 HOATZ DNAH7 MAST4 PTPRG DNAH5

2.81e-061961397af4cdc61830685a888a1209826c23bcf54a43084
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 PDGFRB SLC19A2 PTPRG MLLT11 HAO2 STEAP1

2.81e-06196139746d665de09f8164690b9a3e0acf0b0afa3f81b3d
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

DNAH3 CFAP251 HOATZ DNAH7 MAST4 PTPRG DNAH5

2.81e-0619613976d02d494196e3f857d53eea46d9419690d43beca
ToppCelldistal-mesenchymal-Lipofibroblast-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS1 PDGFRB SLC19A2 ABCA8 MLLT11 HAO2 STEAP1

2.90e-061971397865010edcd7e3f79f505fcef7b33882095994aa8
ToppCelldistal-mesenchymal-Lipofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS1 PDGFRB SLC19A2 ABCA8 MLLT11 HAO2 STEAP1

2.90e-061971397ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 DNAH3 CFAP251 HOATZ GPR162 DNAH7 DNAH5

2.90e-061971397e453d085182364ca347cbcc9dc995c62c3353016
ToppCellnormal_Lung-Epithelial_cells-AT1|Epithelial_cells / Location, Cell class and cell subclass

COL4A2 COL4A3 ABCA1 SYNPO ABCA8 WWC2 RHOF

2.90e-0619713977d19b93d6853828e2a036e37c4887edb1de4503c
ToppCellCOPD-Stromal|COPD / Disease state, Lineage and Cell class

COL4A2 ADAMTS1 PDGFRB ABCA9 ABCA8 PTPRG STEAP1

2.90e-061971397d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FILIP1 DNAH3 CFAP251 HOATZ GPR162 DNAH7 DNAH5

2.90e-061971397d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A2 DOK5 PDGFRB NLGN1 ABLIM3 ABCA8 PTPRG

3.00e-06198139721cf4d81386761d09d0f6829c01c198e5524176d
ToppCell3'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FILIP1 ADAMTS1 PDGFRB SLC19A2 ABCA9 ABCA8 TNXB

3.00e-061981397698166b4ca173176ed563af6a1efc8c7d0a18e0b
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A3 FILIP1 TMTC2 WWC2 ATP8A1 MAST4 SCN1A

3.10e-061991397725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellmild-B_memory|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

COL4A3 STRBP SYNPO FBXO10 CD19 BTK DNAH8

3.10e-061991397025bb65629d9e20c374e8f1ba08c36d1bb569190
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS1 ENPP2 SYNPO ABLIM3 LEPR MAST4 PTPRG

3.10e-0619913976a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCellBiopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

ADAMTS1 PDGFRB ABCA9 ABCA8 MLLT11 TNXB STEAP1

3.21e-0620013972c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

COL4A2 ADAMTS1 PDGFRB ABCA9 ABCA8 TNXB STEAP1

3.21e-062001397954fee8425673e76198be414f5f6c4e3597c1919
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS1 PDGFRB ABCA9 ABCA8 LEPR TNXB STEAP1

3.21e-0620013972e4ab7fbd94d3d865ef6188d3b4916d2bf1b8d89
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PDGFRB ABCA9 ABCA8 LEPR PTPRG TNXB

3.21e-062001397b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A2 PDGFRB ABCA9 ABCA8 LEPR PTPRG TNXB

3.21e-062001397c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellfacs-Aorta-Heart-3m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 UBE2O CADPS SCN1A SLC17A7 USH2A

5.00e-06139139622a769d5195ed761ef333ef542746e1ba617a698
ToppCellfacs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 UBE2O CADPS SCN1A SLC17A7 USH2A

5.00e-061391396292533e04178dd36d57377562077f9deb2cb9746
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

OR13F1 TMTC2 OPRD1 PCDH11X ABCB11 CDA

5.89e-06143139624fd24846fbef049af669a57d42fcc18928d2b27
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLA2G7 SLC29A3 VWA8 CYP27A1 PCDH11X C5

7.45e-06149139613b445c13bb8f31ff0876addd1baf969ae220ea3
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A3 FILIP1 DNAH3 LRRC37A2 CD19 DNAH8

7.74e-06150139653de595376a9fc92491dfd58ff25938b0bf79903
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYS ABCB11 CYP4F22 USH2A DNAH8 ALK

7.74e-0615013960205318a870e091add66ee4305747dda9f51510d
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A3 FILIP1 DNAH3 LRRC37A2 CD19 DNAH8

7.74e-061501396e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

PLA2G7 DOCK8 CYP27A1 WWC2 FRRS1 DNAH5

8.04e-0615113964533bccc996395f74b16af939ce79b6fe253c073
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

PLA2G7 DOCK8 CYP27A1 WWC2 FRRS1 DNAH5

8.04e-061511396edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellAT1-AT2_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A2 COL4A3 SYNPO RGS11 C5 SLC5A8

9.34e-061551396010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B ENPP2 SLC19A2 CPS1 ABCB11 IL1RAP

9.69e-061561396e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL4A3 FILIP1 DNAH3 LRRC37A2 CD19 DNAH8

9.69e-061561396a5930b455e5c8586c43c50106ab4d8a1e5e9e3d6
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH3 EYS CADPS USH2A DNAH8 ALK

1.08e-0515913965335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH3 EYS CADPS CYP4F22 USH2A ALK

1.24e-05163139619c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZDHHC2 RGS11 CCN6 PYCARD PRKCQ RHOF

1.29e-0516413961a9b444d2c6abcc83d4355ec5228b27541df2bd0
ToppCelldroplet-Liver-Hepatocytes-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D32 ATP8A1 MAST4 PER2 DDHD2

1.41e-0598139595162072f3afc95e46f29db3d79ebd930bc09726
ToppCelldroplet-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 IDH1 FAM151A CDA SLC5A8 HAO2

1.48e-051681396dd48da83c32d41a62f80cd7e5e5c64e42776fa27
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NBPF3 COL4A2 ABCA1 ADAMTS1 ABCA8 PTPRG

1.53e-051691396c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

COL4A2 COL4A3 TMTC2 ABCA9 ABCA8 PTPRG

1.53e-0516913966373562ab3b1765060212a6a53d6543e7e942e80
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CFAP251 HOATZ GPR162 DNAH7 DNAH5

1.74e-051731396c3762655caa79ac4879876f470d32578a3c93b01
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PDGFRB ABCA9 ABCA8 LEPR TNXB STEAP1

1.92e-0517613962e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 FILIP1 ADAMTS1 SYNPO TNXB STEAP1

1.92e-051761396bfa1633e1b7a8a2f04d37fa07284fe9bc0199f46
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

PDGFRB ABCA9 ABCA8 LEPR TNXB STEAP1

1.92e-051761396f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DOK5 PDGFRB ABCA9 ABCA8 STEAP1

1.98e-051771396cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL4A3 ADAMTS1 SYNPO PTPRG TNXB STEAP1

1.98e-0517713963d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS1 SLC19A2 TMTC2 ABCA9 PTPRG MLLT11

1.98e-051771396bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellCOVID-19_Moderate-B_intermediate|COVID-19_Moderate / disease group, cell group and cell class

COL4A3 STRBP SYNPO CD19 GUCY2C DNAH8

1.98e-05177139668e3d12a0c048a2d0f1b9680c7338a35855bba30
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

COL4A2 DOK5 PDGFRB ABCA9 ABCA8 STEAP1

1.98e-051771396db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

CPS1 ABCA9 ABCA8 LEPR TNXB STEAP1

2.05e-051781396a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

CPS1 ABCA9 ABCA8 LEPR TNXB STEAP1

2.05e-051781396371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A2 FILIP1 CFAP251 ADAMTS1 ABCA9 ABCA8

2.05e-051781396d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A2 FILIP1 FBXO10 MAST4 DNAH8 TNXB

2.11e-051791396025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

COL4A2 ADAMTS1 PDGFRB FRY TBC1D1 MYOM2

2.11e-051791396111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A2 COL4A3 FILIP1 ABCA8 WWC2 NRG3

2.11e-0517913964f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellEndothelial|World / shred by cell class for turbinate

COL4A2 ADAMTS1 ABLIM3 ABCA8 ABCB1 TNXB

2.11e-051791396052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 CFAP251 STRBP HOATZ DNAH7 DNAH5

2.18e-0518013961f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL4A2 COL4A3 TMTC2 ABCA9 ABCA8 PTPRG

2.25e-0518113962b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN1 ABLIM3 MAST4 SLC5A8 ACMSD HAO2

2.25e-0518113969542c19edc9bd2cba68c01c2a8407705398e3011
DrugSertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A

CHRNA6 ABCA1 ABCA2 SZT2 PDGFRB SIGLEC8 ENPP2 CPS1 LEPR CCN6

3.02e-07198135103550_UP
Drug7-hydroxymitragynine

OPRD1 OPRK1 ABCB1

8.12e-0741353ctd:C482678
DrugDextropropoxyphene

OPRD1 OPRK1 ABCB1

7.01e-0671353ctd:D011431
DrugDtds

OPRK1 CDA CDK2

7.01e-0671353CID000130348
DrugSNC-121

OPRD1 OPRK1 ABCB1

1.12e-0581353CID000197687
DrugBetamethasone-d5

COL4A3 CHRNA6 PDGFRB ENPP2 ANXA7 CYP27A1 CPS1 GPR162 ABCB1 CCN6 CD19 PYCARD ABCB11 CYP4F22 PRKCQ MYOM2 MPHOSPH9 LTB4R HSD17B3 IL1RAP RHOF CDK2

1.29e-05134013522CID000003003
DrugMorphine

DNAH3 MYO19 CYP27A1 EZH2 LEPR OPRD1 OPRK1 ABCB1 PER2 PYCARD SLC17A7 SLC17A6

1.45e-0544613512ctd:D009020
DrugNorfloxacin [70458-96-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A

COL4A3 DMXL2 ABCA1 ENPP2 TUB TRANK1 PER2 KCNS1

2.36e-0519713582253_UP
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A

SZT2 BHLHE40 LEPR FRY MAST4 SMG7 KCNS1 HSD17B3

2.45e-0519813587232_UP
DrugPhthalylsulfathiazole [85-73-4]; Down 200; 10uM; HL60; HT_HG-U133A

PLA2G7 DMXL2 SLC29A3 ENPP2 CPS1 SMG7 LTB4R IL1RAP

2.45e-0519813583033_DN
DrugMetampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A

DMXL2 CYP27A1 SYNPO RGS11 PER2 SLC17A7 KCNS1 HSD17B3

2.45e-0519813582286_UP
Drugsilychristin

ABCB1 ABCB11 ALK CDK2

2.50e-05291354CID000441764
DrugSbCl5

ZDHHC2 GPR162 ABCB1

3.25e-05111353CID000024294
Drugerinacine E

OPRD1 OPRK1

3.49e-0521352CID005317180
DrugDynorphin (1-11)

OPRD1 OPRK1

3.49e-0521352CID003086114
Drug(-)-EKC

OPRD1 OPRK1

3.49e-0521352CID000042800
Drug2-aminooxazole

OPRD1 OPRK1

3.49e-0521352CID000558521
DrugMR-1353

OPRD1 OPRK1

3.49e-0521352CID000197198
DrugGSK343

EZH2 DICER1

3.49e-0521352ctd:C586265
Drugtrefentanil

OPRD1 OPRK1

3.49e-0521352CID000060727
DrugOxycodone

ADAMTS1 CYP27A1 ABCA8 OPRD1 OPRK1 PYCARD HAO2

3.64e-051531357ctd:D010098
Drugdicyclohexyl phthalate

ABCA1 PDGFRB STRBP CPS1 EZH2 DICER1 OPRK1 PER2 CADPS BTK ABCB11 PRKCQ SLC5A8 MTX1 ALK CDK2

3.70e-0583613516ctd:C036042
DrugAdenosine triphosphate

ABCA1 ABCB1 ABCB11 ALK

4.23e-05331354DB00171
DrugAC1L2AC4

ABCB1 SPPL2A ABCB11

4.31e-05121353CID000068732
Drugpyrazinamide

EZH2 DICER1 TBC1D1 ACMSD RHOF

5.26e-05681355CID000001046
Drugasimadoline

OPRD1 OPRK1 ABCB1

5.58e-05131353CID000179340
DrugAC1NAE4O

PLA2G7 ABCA1 ABCB1 WWC2 PYCARD ABCB11

6.44e-051151356CID004475485
DrugCholic Acid

ABCA1 CYP27A1 ABCB1 ABCB11 HELLS

8.42e-05751355ctd:D019826
Drugmitragynine

OPRD1 OPRK1 ABCB1

8.80e-05151353ctd:C001801
DrugTRK 820

OPRD1 OPRK1

1.04e-0431352ctd:C111212
DrugOxycodone

OPRD1 OPRK1

1.04e-0431352DB00497
DrugHydromorphone

OPRD1 OPRK1

1.04e-0431352DB00327
DrugCodeine

OPRD1 OPRK1

1.04e-0431352DB00318
DrugCarfentanil

OPRD1 OPRK1

1.04e-0431352DB01535
DrugMorphine

OPRD1 OPRK1

1.04e-0431352DB00295
DrugHydrocodone

OPRD1 OPRK1

1.04e-0431352ctd:D006853
Drug3-Methylfentanyl

OPRD1 OPRK1

1.04e-0431352DB01571
DrugHeroin

OPRD1 OPRK1

1.04e-0431352DB01452
Drug3-Methylthiofentanyl

OPRD1 OPRK1

1.04e-0431352DB01439
Drugmorphine-7,8-oxide

OPRD1 OPRK1

1.04e-0431352CID005491901
DrugLevorphanol

OPRD1 OPRK1

1.04e-0431352ctd:D007981
DrugLevallorphan

OPRD1 OPRK1

1.04e-0431352ctd:D007977
DrugNSC11411

OPRD1 OPRK1

1.04e-0431352CID000408117
DrugNSC652297

ABCB1 SLC5A8

1.04e-0431352CID000092781
DrugBuprenorphine

OPRD1 OPRK1

1.04e-0431352DB00921
DrugLevorphanol

OPRD1 OPRK1

1.04e-0431352DB00854
DrugRemifentanil

OPRD1 OPRK1

1.04e-0431352DB00899
DrugNalbuphine

OPRD1 OPRK1

1.04e-0431352DB00844
DrugFentanyl

OPRD1 OPRK1

1.04e-0431352DB00813
Drugefonidipine

ABCA1 ABCB1

1.04e-0431352ctd:C066425
DrugSufentanil

OPRD1 OPRK1

1.04e-0431352DB00708
DrugRo 64-6198

OPRD1 OPRK1

1.04e-0431352CID009844019
DrugPropoxyphene

OPRD1 OPRK1

1.04e-0431352DB00647
DrugButorphanol

OPRD1 OPRK1

1.04e-0431352DB00611
DrugButorphanol

OPRD1 OPRK1

1.04e-0431352ctd:D002077
Drugcyclorphan

OPRD1 OPRK1

1.04e-0431352ctd:C084603
Drugup hit

OPRD1 OPRK1

1.04e-0431352CID000129713
DrugElacridar

ABCB1 ABCB11

1.04e-0431352ctd:C083501
DrugAlvimopan

OPRD1 OPRK1

1.04e-0431352DB06274
Drugdextrallorphan

OPRD1 OPRK1

1.04e-0431352ctd:C044130
Drug14-phenylpropoxymetopon

OPRD1 OPRK1

1.04e-0431352ctd:C478565
DrugNSC612112

OPRD1 OPRK1

1.04e-0431352CID000356432
Drugindolin-3-one

OPRD1 OPRK1

1.04e-0431352CID000230915
Drugnaloxazine

OPRD1 OPRK1

1.04e-0431352CID003081567
Drug3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester

ABCB1 ABCB11

1.04e-0431352ctd:C541506
DrugEtilefrine hydrochloride [534-87-2]; Up 200; 18.4uM; HL60; HT_HG-U133A

PLA2G7 CHRNA6 ABCA2 RTEL1 SUN1 KCNS1 PRKCQ

1.05e-0418113572930_UP
Drugchalepin

OPRD1 OPRK1 MTX1

1.08e-04161353CID000119066
Drugleflunomide

ADAMTS1 VWA8 ENPP2 ANXA7 SLC19A2 IDH1 ABCA8 ATP6V1H SPPL2A PER2 PTPRG C5 IL1RAP TSSK4 HAO2

1.19e-0482713515ctd:C045463
DrugSanguinarine [2447-54-3]; Down 200; 12uM; HL60; HT_HG-U133A

PIEZO1 BHLHE40 MPHOSPH9 DDHD2 IL1RAP NUP160 CDK2

1.20e-0418513572927_DN
DrugProtriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

COL4A2 DOK5 SZT2 RTEL1 CYP27A1 CPS1 BHLHE40

1.29e-0418713575438_UP
Drug1,2,5,6-dibenzanthracene

ZDHHC2 COL4A2 ABCA1 SLC19A2 TMTC2 DYSF GPR162 BHLHE40 LEPR ABCB1 FRRS1 PER2 PTPRG C5 LTB4R

1.36e-0483713515ctd:C026486
Drugsodium

CHRNA6 SLC29A3 ADAMTS1 ENPP2 SLC19A2 IDH1 OPRD1 ATP6V1H PTPRG GUCY2C PYCARD SLC17A7 ABCB11 PRKCQ SLC5A8 SLC17A6

1.53e-0494413516CID000000923
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; HL60; HT_HG-U133A

DOK5 SIGLEC8 CYP27A1 NLGN1 ABCB1 PRKCQ ALK

1.57e-0419313572509_UP
DrugMetampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

COL4A3 SZT2 RTEL1 HHAT KCNS1 LTB4R ALK

1.67e-0419513575115_UP
DrugDiphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; PC3; HT_HG-U133A

ABCA1 SZT2 DNAH7 SMG7 KCNS1 HAO2 ALK

1.72e-0419613573743_DN
DrugAlcuronium chloride [15180-03-7]; Down 200; 5.4uM; MCF7; HT_HG-U133A

VWA8 RTEL1 DICER1 MAST4 SLC17A7 KCNS1 MPHOSPH9

1.72e-0419613574409_DN
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A

SZT2 SUN1 CPS1 GPR162 HOXC4 TRANK1 PRKCQ

1.78e-0419713572328_UP
DrugD-cycloserine [68-41-7]; Up 200; 39.2uM; MCF7; HT_HG-U133A

CHRNA6 SZT2 CYP27A1 DYSF SLC17A7 CDA LTB4R

1.78e-0419713573562_UP
Drugmonomethyl phthalate

ABCA1 PDGFRB EZH2 DICER1 OPRK1 ATP6V1H PER2 CADPS BTK ABCB11 CDA PRKCQ SLC5A8 MTX1 ALK CDK2

1.78e-0495713516ctd:C517284
DrugHalcinonide [3093-35-4]; Down 200; 8.8uM; PC3; HT_HG-U133A

COL4A2 ABCA1 SUN1 BHLHE40 DNAH7 KCNS1 CDK2

1.83e-0419813573680_DN
DrugTrimethobenzamide hydrochloride [554-92-7]; Up 200; 9.4uM; HL60; HG-U133A

ABCA2 EZH2 HOXC4 KCNS1 MPHOSPH9 IL1RAP NUP160

1.83e-0419813572002_UP
DrugCanrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; MCF7; HT_HG-U133A

SZT2 CYP27A1 DYSF DNAH7 DICER1 KCNS1 LTB4R

1.83e-0419813572228_UP
DrugAzlocillin sodium salt [37091-65-9]; Up 200; 8.2uM; HL60; HT_HG-U133A

DOK5 CHRNA6 ABCA2 RTEL1 CYP27A1 SYNPO SLC17A7

1.83e-0419813572727_UP
DrugNiridazole [61-57-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A

COL4A2 SIGLEC8 ENPP2 CYP27A1 DYSF DICER1 ALK

1.83e-0419813575682_UP
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A

COL4A2 RTEL1 SIGLEC8 DICER1 LEPR HOXC4 SLC17A7

1.83e-0419813576178_UP
DrugErgocryptine-alpha [511-09-1]; Down 200; 7uM; MCF7; HT_HG-U133A

CHRNA6 BHLHE40 LEPR HOXC4 SMG7 PER2 KCNS1

1.83e-0419813573900_DN
DrugDanmme

OPRD1 OPRK1 ABCB1

1.84e-04191353CID005486529
DrugClenbuterol hydrochloride [21898-19-1]; Up 200; 12.8uM; MCF7; HT_HG-U133A

DOK5 ENPP2 HOXC4 HHAT CARF LTB4R ALK

1.89e-0419913573228_UP
DrugNorgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A

NPHS1 COL4A3 SZT2 PDGFRB CPS1 FRY TRANK1

1.89e-0419913573606_UP
Drug17-isoprogesterone

BRIX1 COL4A3 CHRNA6 ABCA2 ADAMTS1 PDGFRB ANXA7 CYP27A1 IDH1 EZH2 BHLHE40 ABCB1 CCN6 GUCY2C TBC1D1 PYCARD PRKCQ HSD17B3

1.94e-04117013518CID000004920
DrugProbucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A

COL4A3 SYNPO CPS1 MAST4 PER2 LTB4R IL1RAP

1.95e-0420013575626_UP
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A

ABCA2 DYSF DICER1 SCN1A HHAT SLC17A7 ALK

1.95e-0420013575570_UP
DrugDynorphins

OPRD1 OPRK1

2.08e-0441352ctd:D004399
DrugAC1L5BQM

OPRD1 OPRK1

2.08e-0441352CID000174892
DrugDiprenorphine

OPRD1 OPRK1

2.08e-0441352DB01548
Drug3B-b

OPRD1 OPRK1

2.08e-0441352CID000533975
Drugtaxinine K

ABCB1 BTK

2.08e-0441352CID005321708
Drugpicenadol

OPRD1 OPRK1

2.08e-0441352CID000053076
Drugsulforhodamine B acid chloride

OPRD1 OPRK1

2.08e-0441352CID000065223
Drug2-methoxy-N-(3-(4-((3-methyl-4-((6-methyl-3-pyridinyl)oxy)phenyl)amino)-6-quinazolinyl)-2-propenyl)acetamide

ABCB1 ABCB11

2.08e-0441352ctd:C521104
DiseaseLiver Cirrhosis, Experimental

ZDHHC2 COL4A2 PDGFRB ENPP2 SLC19A2 CPS1 DYSF ABLIM3 ABCB1 FRY PYCARD HAO2 HELLS

5.41e-0577413413C0023893
DiseaseHypotension, Orthostatic

OPRD1 ABCB1

6.12e-0531342C0020651
DiseaseBipolar Disorder

DOK5 CHRNA6 NLGN1 BHLHE40 TRANK1 PER2 SLC17A7 NRG3 DNAH8 SLC17A6

6.78e-0547713410C0005586
DiseaseColorectal Carcinoma

ZDHHC2 DNAH3 ABCA1 IDH1 ABCA9 ABCA8 ABCB1 GUCY2C PYCARD PCDH11X ABCB11 DNAH8

8.98e-0570213412C0009402
DiseaseDiffuse Large B-Cell Lymphoma

EZH2 ABCB1 ALK CDK2

1.16e-04551344C0079744
Diseaseretinal vasculature measurement

COL4A2 PDGFRB STRBP TMTC2 CPS1 DYSF FRY EYS EDEM2 DNAH5

1.31e-0451713410EFO_0010554
Diseasecomparative body size at age 10, self-reported

SEC16B LRRC37A2 LEPR OPRK1 MAST4 CADPS RPTOR TNRC6A ALK

1.34e-044201349EFO_0009819
DiseaseWithdrawal Symptoms

CHRNA6 OPRD1 OPRK1 PER2

1.43e-04581344C0087169
DiseaseDrug Withdrawal Symptoms

CHRNA6 OPRD1 OPRK1 PER2

1.43e-04581344C0086189
DiseaseSubstance Withdrawal Syndrome

CHRNA6 OPRD1 OPRK1 PER2

1.43e-04581344C0038587
Diseaseglioblastoma (is_implicated_in)

PDGFRB IDH1 EZH2

1.73e-04241343DOID:3068 (is_implicated_in)
DiseaseAlbuminuria

NPHS1 LEPR PYCARD

1.73e-04241343C0001925
Diseasesystemic mastocytosis

ABCA1 ABCA2 EYS

1.96e-04251343MONDO_0016586
DiseaseSchizophrenia

ABCA1 PDGFRB NLGN1 BHLHE40 DICER1 ABCB1 HHAT EDEM2 SLC17A7 NRG3 TNXB ALK SLC17A6

2.00e-0488313413C0036341
DiseaseGranulosa Cell Cancer

DICER1 LEPR

2.03e-0451342C1567257
Diseaseinternal carotid intimal medial thickness

MAST4 NRG3

2.03e-0451342EFO_0005053
DiseaseAdult Diffuse Large B-Cell Lymphoma

EZH2 CDK2

2.03e-0451342C1332201
Diseasewhite matter integrity, age at assessment

COL4A2 OR2B3 CARF

2.21e-04261343EFO_0004641, EFO_0008007
Diseaseblood nickel measurement

ZDHHC2 OPRK1 EYS RPTOR USH2A

2.25e-041201345EFO_0007583
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

SEC16B NLGN1 HOXC4 PTPRG RPTOR TNRC6A SKOR1 ACMSD

2.69e-043641348EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseaseamino acid measurement

SYNPO NLGN1 CPS1 GPR162 DNAH7 PTPRG GUCY2C HHAT C5 NRG3 ALK

2.78e-0467813411EFO_0005134
DiseaseColorectal Neoplasms

ABCA1 ABCA9 ABCA8 ABCB1 GUCY2C PYCARD ABCB11

2.84e-042771347C0009404
DiseaseLeukemia, Myelomonocytic, Chronic

PDGFRB EZH2

3.03e-0461342C0023480
Diseasecholine measurement

ABCA1 CPS1 LEPR ABCB11 HSD17B3

3.26e-041301345EFO_0010116
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

NPHS1 COL4A3 NUP160

3.40e-04301343C1868672
Diseasepentachlorophenol measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022071
Diseaseparathion measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022070
Diseasepotassium chromate measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022072
Diseasemercuric chloride measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022068
Diseaseheptachlor epoxide measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022067
Diseasemethoxychlor measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022069
Disease4,6-dinitro-o-cresol measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022053
Disease2,4,5-trichlorophenol measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022052
Diseaseazinphos methyl measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022055
Diseasealdrin measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022054
Diseasedicofol measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022060
Diseasedisulfoton measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022062
Diseasedieldrin measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022061
Diseaseendrin measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022064
Diseaseendosulfan measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022063
Diseaseheptachlor measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022066
Diseaseethion measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022065
Diseasechlorpyrifos measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022057
Diseasecadmium chloride measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022056
Diseasediazinon measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022059
Diseasedibutyl phthalate measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0022058
Diseaseenvironmental exposure measurement

OPRK1 EYS RPTOR USH2A

3.47e-04731344EFO_0008360
Diseasecoronary artery disease

COL4A2 ABCA1 DOCK8 TUB ABCA8 MAST4 RPTOR HHAT CARF EDEM2 C5 TNXB RHOF ALK NUP160

3.55e-04119413415EFO_0001645
DiseaseDDT metabolite measurement

OPRK1 EYS RPTOR USH2A

3.66e-04741344EFO_0007886
Diseasebody fat percentage

SEC16B DMXL2 NLGN1 HOXC4 PTPRG RPTOR TNRC6A SKOR1 ACMSD

4.05e-044881349EFO_0007800
DiseaseB-cell lymphoma (is_implicated_in)

EZH2 BTK

4.24e-0471342DOID:707 (is_implicated_in)
Diseasecolorectal adenocarcinoma (is_implicated_in)

EZH2 ABCB1 FAM151A

5.39e-04351343DOID:0050861 (is_implicated_in)
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A TNRC6A

5.63e-0481342C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A TNRC6A

5.63e-0481342C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A TNRC6A

5.63e-0481342C0338479
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A TNRC6A

5.63e-0481342C0751120
DiseaseMyoclonic Encephalopathy

SCN1A TNRC6A

5.63e-0481342C0438414
Diseasediffuse large B-cell lymphoma (is_marker_for)

EZH2 DICER1

5.63e-0481342DOID:0050745 (is_marker_for)
DiseaseMyoclonic Absence Epilepsy

SCN1A TNRC6A

5.63e-0481342C0393703
Diseasecystic fibrosis (implicated_via_orthology)

ABCB1 ABCB11

7.22e-0491342DOID:1485 (implicated_via_orthology)
DiseaseMyoclonic Epilepsy

SCN1A TNRC6A

7.22e-0491342C0014550
Diseaseceramide measurement

SEC16B ABCA1 NLGN1 CPS1 EYS PRKCQ

7.36e-042351346EFO_0010222
Diseasealkaline phosphatase measurement

NBPF3 COL4A2 SEC16B ZNF318 CPS1 BHLHE40 LEPR MED24 TRANK1 EDEM2 ABCB11 CDA NUP160

7.45e-04101513413EFO_0004533
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A TNRC6A

8.99e-04101342C0917800
Diseasecerebrospinal fluid biomarker measurement

PLA2G7 PDGFRB LEPR ATP6V1H

9.78e-04961344EFO_0006794
Diseasecocaine use

CHRNA6 SCN1A

1.10e-03111342C3496069
DiseaseHyperhomocysteinemia

NPHS1 PYCARD

1.10e-03111342C0598608
DiseaseMyoclonic Astatic Epilepsy

SCN1A TNRC6A

1.10e-03111342C0393702
DiseaseMental Depression

CHRNA6 SLC29A3 OPRK1 ABCB1 PER2 ALK

1.10e-032541346C0011570
Diseasefibrinogen measurement, tissue plasminogen activator measurement

CPS1 LEPR SPPL2A

1.13e-03451343EFO_0004623, EFO_0004791
Diseasefibrinogen measurement, plasminogen activator inhibitor 1 measurement

CPS1 LEPR SPPL2A

1.13e-03451343EFO_0004623, EFO_0004792
Diseaseblood cobalt measurement

OPRK1 EYS RPTOR USH2A

1.18e-031011344EFO_0007577
DiseaseWeight Gain

ZDHHC2 EZH2 LEPR PYCARD

1.23e-031021344C0043094
DiseaseMalignant neoplasm of breast

ADAMTS1 STRBP LRRC37A2 ZNF318 EZH2 DYSF LEPR ABCB1 PER2 BTK CDA ALK SLC17A6

1.24e-03107413413C0006142
DiseaseNeuroblastoma

DOCK8 ABCB1 ALK

1.28e-03471343C0027819
DiseaseHematologic Neoplasms

IDH1 ABCB1

1.31e-03121342C0376545
DiseaseAgammaglobulinemia

CD19 BTK

1.31e-03121342C0001768
Diseaseocular hypertension, response to triamcinolone acetonide

VWA8 LIPK FRRS1

1.45e-03491343EFO_0006954, EFO_1001069
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A TNRC6A

1.55e-03131342C0751122
Diseasefree androgen index

COL4A2 ZNF318 CPS1 ABCA8 LEPR PTPRG NUP160

1.65e-033741347EFO_0007005
DiseaseSquamous cell carcinoma of the head and neck

ABCB1 IL1RAP CDK2

1.72e-03521343C1168401
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

NPHS1 ABCA1

1.80e-03141342DOID:10976 (biomarker_via_orthology)
Diseaseserum urea measurement

COL4A2 CYP27A1 ZNF318 CPS1 SPPL2A

2.01e-031951345EFO_0009795
DiseaseIschemic stroke, fibrinogen measurement

CPS1 LEPR SPPL2A

2.02e-03551343EFO_0004623, HP_0002140
DiseaseHypogonadotropic hypogonadism

SLC29A3 LEPR

2.07e-03151342C0271623
DiseaseRhabdomyosarcoma

DICER1 ALK

2.07e-03151342C0035412
DiseasePrimary hypogonadism

SLC29A3 LEPR

2.07e-03151342C0948896
DiseaseHypogonadism, Isolated Hypogonadotropic

SLC29A3 LEPR

2.07e-03151342C3489396
DiseaseDepressive disorder

CHRNA6 SLC29A3 OPRK1 ABCB1 PER2 ALK

2.11e-032891346C0011581
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

CPS1 LEPR SPPL2A

2.13e-03561343EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
DiseaseLiver carcinoma

ZDHHC2 ADAMTS1 IDH1 EZH2 ABCB1 PYCARD IL1RAP HAO2

2.27e-035071348C2239176
Diseasefibrinogen measurement, factor VII measurement

CPS1 LEPR SPPL2A

2.35e-03581343EFO_0004619, EFO_0004623
Diseaseatherosclerosis (is_implicated_in)

COL4A2 PLA2G7

2.36e-03161342DOID:1936 (is_implicated_in)
DiseaseHypogonadism

SLC29A3 LEPR

2.36e-03161342C0020619
Diseasemean platelet volume

CFAP251 DOCK8 CPS1 LEPR OPRD1 FRY TRANK1 MAST4 TNRC6A MAP3K11 KCNS1 RHOF

2.42e-03102013412EFO_0004584
Diseasediffuse plaque measurement

VWA8 DOCK8 ABLIM3 ABCA8 EYS MAST4 PTPRG CADPS NRG3 SLC17A6

2.47e-0375813410EFO_0010699
DiseaseInborn Errors of Metabolism

PLA2G7 LEPR

2.66e-03171342C0025521
Diseasepartial epilepsy

TBC1D32 SCN1A

2.66e-03171342EFO_0004263
DiseaseAntibody Deficiency Syndrome

LEPR C5

2.66e-03171342C0003257
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

ABCA1 CYP27A1

2.66e-03171342DOID:13619 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PPIMNYMISYSWTKN

PTPRG

376

P23470
PSKMRKLFSFTPAWN

PYCARD

156

Q9ULZ3
MKARSSSYADPWTPP

ABLIM3

531

O94929
SSQYSSFLFWRMPIP

MLLT11

6

Q13015
RNDYSYWLSTPALMP

COL4A3

1516

Q01955
LEKSDNPYPWPMFSS

TBC1D32

891

Q96NH3
VRWSPPEVLMYSKFS

BTK

561

Q06187
TFFWIPMAASFTPYI

ABCA9

1026

Q8IUA7
SATAYLPMLEKCWYP

BHLHE40

331

O14503
NLVFTPAWFSPIMYK

FBXO10

181

Q9UK96
PAWFSPIMYKTTSGH

FBXO10

186

Q9UK96
GWSITPLMYPASFVF

ABCA1

1746

O95477
NDKSYWLSTTAPLPM

COL4A2

1561

P08572
KFSAPEWPYMLVGSV

ABCB11

746

O95342
QALSTVPVMFSYWAK

ACMSD

71

Q8TDX5
LYMWLSNSPHGPSAK

BRIX1

126

Q8TDN6
ILALFMPPTYYDAWS

ANXA7

251

P20073
MWDYFVAKPFLPLSD

DMXL2

2456

Q8TDJ6
PFSTTDSAYEWKMPK

DICER1

1471

Q9UPY3
VMKFRPLTWQTSHPY

BMS1

241

Q14692
FFGIYSSLWPAIPMA

ATP8A1

1021

Q9Y2Q0
DKSTPVYPLTMTWSF

CFAP251

241

Q8TBY9
YWVMNAPTVAAPTKL

RGS11

281

O94810
QPWSPCSAYMITSFL

ADAMTS1

441

Q9UHI8
VNKTYPVDMSPTFTW

GUCY2C

401

P25092
KPTVSVFSMFRYSNW

ABCB1

31

P08183
MPSWPTAAYATSSYL

NRG3

221

P56975
QMPTFSAPSWMAAIY

CADPS

1041

Q9ULU8
NPEPSLMWYKDSRTV

NPHS1

471

O60500
WTDPKLNSPMYFFLG

OR10AD1

51

Q8NGE0
IYMYLQPPSSTSKDW

OR2B3

256

O76000
STLPNWMAEFKRFTP

HELLS

281

Q9NRZ9
IQKKPTMYPPWDSTF

PRKCQ

46

Q04759
KLSSIIPSAFPSWYM

MAGEC3

591

Q8TD91
IPSAFPSWYMDALKD

MAGEC3

596

Q8TD91
TSSSMSVIRPDWPYF

EYS

1806

Q5T1H1
QPLWFKDMYKPLSAT

LRRC37A2

1646

A6NM11
VSFFSLKSDSAPPWM

GPR162

291

Q16538
MKFYAVVATSPASWE

MYO19

146

Q96H55
YFPSSVKPTITWYMG

IL1RAP

166

Q9NPH3
PATRLMWKSQYVPYD

CARF

256

Q8N187
TVSMPVFQSLEAYWP

EDEM2

306

Q9BV94
LNAVASVPIMYSWSP

EZH2

101

Q15910
SFTSPYKLPLWSMCS

PER2

241

O15055
SNLPMWKPMLYTVAF

DNAH8

4041

Q96JB1
MAWKSFTRAPYPALQ

DDHD2

596

O94830
AFYLSKPDETPNAWM

MPHOSPH9

191

Q99550
WRFKLSCMPPNSTYD

LEPR

31

P48357
SLSTMVPLPRSAYWQ

DOK5

256

Q9P104
LWLTMENPGYSLPSK

KCNS1

206

Q96KK3
SSWAVSFQPAKYARM

NLGN1

341

Q8N2Q7
MGKYNWVTTPTTFKP

PCDH11X

916

Q9BZA7
WKTNMSLCFPRYPSE

LTB4R

161

Q15722
PFDWQYINPVAHMKS

PLA2G7

21

Q13093
TLPFQSAKYLMETWP

OPRD1

101

P41143
QLPAASTSYSFPWML

HHAT

191

Q5VTY9
WTLSIPPDMSASYQS

NBPF3

351

Q9H094
SYKTMPAYRNLPLIW

CCN6

191

O95389
KYNGMITWTPPAIFK

CHRNA6

141

Q15825
IPADYVAIKAPMFSW

CPS1

1301

P31327
SFQMALSKGWPLYLS

IDH1

196

O75874
SPKAFMADQQLPYWV

KDM1B

126

Q8NB78
KYRMPFAWAPISLSS

DOCK8

396

Q8NF50
FYPPLMQRTSWTLAA

DNAH3

81

Q8TD57
GKVPAMWAAKSYPSL

DNAH3

3921

Q8TD57
SPSGKLMSPKLYVWA

CD19

146

P15391
YPKATLSPGWTTFYM

FAM151A

201

Q8WW52
PDPAFTYEWTKVASM

C19orf44

536

Q9H6X5
LNLPDSWKTYAMTGF

FRRS1

506

Q6ZNA5
PSNPRYGMWTIKAKY

C5

191

P01031
LMFQNSLYATFLPKW

CYP27A1

246

Q02318
FRMWLTSYPSPNFPV

DNAH7

3516

Q8WXX0
SSAASKQPIVYPWMK

HOXC4

126

P09017
LYGWSITPIMYPASF

ABCA2

1881

Q9BZC7
PSSLKMNKSYLLEPW

MAST4

1861

O15021
AWPYAFTRLQSVMPL

FRY

876

Q5TBA9
TSMPDYKPSFPKWAR

CDK2

231

P24941
SKPVYVINWFMSFGP

FAM104B

86

Q5XKR9
GIALFPWPLYSMYSA

HSD17B3

186

P37058
PWPLYSMYSASKAFV

HSD17B3

191

P37058
AFAVAWFLPMPQKSL

SLC19A2

201

O60779
PDTSFLWFTSPYKTM

DYSF

2021

O75923
SSGISWMLFNLAKYP

CYP4F22

341

Q6NT55
FLMPLWTSYTVSKQA

ENPP2

626

Q13822
YAWMAPEVIKASTFS

MAP3K11

286

Q16584
SSGSQWKPMLYAVAF

DNAH5

4176

Q8TE73
MASYLLPGQKSPWFF

FAM120B

301

Q96EK7
NYISKGSTFLPLKWM

PDGFRB

856

P09619
PLKWMAPESIFNSLY

PDGFRB

866

P09619
TMPFQSTVYLMNSWP

OPRK1

111

P41145
IWYSSSALSPMLANF

OR13F1

71

Q8NGS4
VTRKWYAEAMPFPLN

MTX1

271

Q13505
PSYPVMEKSLEFWRA

RTEL1

561

Q9NZ71
SPSSAWMEPRYKEAA

SZT2

1276

Q5T011
EYWMFKLRNSSSPAT

SLC29A3

76

Q9BZD2
AATVYPTFPMFWPAA

SKOR1

481

P84550
VHFMKNYNPSAIWEP

USH2A

1676

O75445
MNPTSYDNVLIKWFP

RHOF

101

Q9HBH0
RCSKNTAWPYFLPML

ATP6V1H

116

Q9UI12
GWYKLFPTSSMVDPA

RIMS4

231

Q9H426
YPPAANELTMRKSWI

FILIP1

856

Q7Z7B0
TMSLPSSWKYPTNAP

SYNPO

756

Q8N3V7
IPYFQMTPISTSLCW

HAO2

191

Q9NYQ3
MPESLLASSPAWKQF

SPATA31A7

881

Q8IWB4
YNAYPLPAVKVSMDW

SMG7

356

Q92540
LAKQFWISASMYPPS

HOATZ

36

Q6PI97
WISASMYPPSESQLV

HOATZ

41

Q6PI97
KFPSTGVDTMPYWNL

MED24

686

O75448
PRPWLSSSFPAYMSK

TMEM69

46

Q5SWH9
LDVSYPPWNLTMTVF

SIGLEC8

241

Q9NYZ4
WTAKKVSAPDQLMPY

SLC5A8

311

Q8N695
LPSSKPFQKYSWSVT

STRBP

331

Q96SI9
SAKLMNPLTKFSTPW

SLC17A7

281

Q9P2U7
FSYEGSWTQKPTSML

PMIS2

91

A0A1W2PS18
SATAPMVWLPYSSID

NUP160

1376

Q12769
DWSARYFAQPVMKIP

RPTOR

961

Q8N122
TMSNPPDWTKNVEYT

SCN1A

146

P35498
KQFVWYTPPTFMIAV

STEAP1

281

Q9UHE8
MFWLVLTSSCPPYIA

ABCA8

1026

O94911
TNMPSPSPDYFTWNL

ALK

231

Q9UM73
TNWPVYMTKPDGTYI

CDA

111

P32320
MPESLLASSPAWKQF

SPATA31A3

881

Q5VYP0
TPWRKFFTSMPVYAI

SLC17A6

301

Q9P2U8
TYMRPSPDFSKIAWF

TDP1

496

Q9NUW8
RGLPYNPFLSDTWSM

TSSK4

211

Q6SA08
VFTLWYNLLPSKQMP

WWC2

816

Q6AWC2
MPESLLASSPAWKQF

SPATA31A1

881

Q5TZJ5
MPESLLASSPAWKQF

SPATA31A5

881

Q5VU36
ARLYWMGNKPPSFSN

TMTC2

241

Q8N394
ITVKMYSPSWPNFDY

SPPL2A

156

Q8TCT8
WMPPPSRADSFKVSY

TNXB

3776

P22105
GPSLYAAPWFLTMFA

TBC1D1

961

Q86TI0
AAPWFLTMFASQFPL

TBC1D1

966

Q86TI0
PVNSKDLQHIWPFMY

UBE2O

186

Q9C0C9
YQPTPWEAASDSMKR

MRPL18

146

Q9H0U6
KALPPMRGFKYTSWS

GTF3C4

156

Q9UKN8
LFLSSKMDPQTYSWV

SEC16B

471

Q96JE7
WKTIFTLPMNPSKEF

ZDHHC2

71

Q9UIJ5
PMNSALIKWLYLPDF

PIEZO1

1076

Q92508
MSLFGIPLWYFSQSP

SUN1

641

O94901
WLSAMQAFLLSSNYP

TRANK1

2286

O15050
LMSPSEVYSWKRPSS

VWA8

1376

A3KMH1
MTSKPHSDWIPYSVL

TUB

1

P50607
AYAASRWPMYPTSQP

ZNF318

796

Q5VUA4
NSSLNWPPYTKKMSS

TNRC6A

1161

Q8NDV7
SPKSPEYWAFSLDEM

LIPK

131

Q5VXJ0
MLWKAPVYSGSSPVS

MYOM2

831

P54296