Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SUMO ligase activity	RANBP2 RGPD8 ZBED1	1.64e-04	20	108	3	GO:0061665
GeneOntologyMolecularFunction	small GTPase binding	DOCK4 RANBP2 RGPD8 RAPGEF4 XPO4 UNC13D RUSC2 FARP1	3.57e-04	321	108	8	GO:0031267
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK4 RANBP2 RGPD8 RAPGEF4 OBSCN ARHGAP35 TBC1D1 FARP1 THG1L RGPD5	4.27e-04	507	108	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK4 RANBP2 RGPD8 RAPGEF4 OBSCN ARHGAP35 TBC1D1 FARP1 THG1L RGPD5	4.27e-04	507	108	10	GO:0030695
GeneOntologyMolecularFunction	cadherin binding	OBSCN APC LARP1 TWF2 PPL PPP1CA EIF4G2 CDH13	5.13e-04	339	108	8	GO:0045296
GeneOntologyMolecularFunction	GTPase binding	DOCK4 RANBP2 RGPD8 RAPGEF4 XPO4 UNC13D RUSC2 FARP1	7.60e-04	360	108	8	GO:0051020
GeneOntologyCellularComponent	nuclear envelope	RANBP2 RGPD8 POLA1 INTS1 APC XPO4 PTGS2 WDR3 OIT3 SYNE2 CST3 ZBED1 RGPD5	6.41e-06	560	108	13	GO:0005635
GeneOntologyCellularComponent	nuclear membrane	RANBP2 RGPD8 INTS1 APC PTGS2 WDR3 SYNE2 CST3 ZBED1	8.33e-05	349	108	9	GO:0031965
GeneOntologyCellularComponent	Pwp2p-containing subcomplex of 90S preribosome	WDR36 WDR3	3.91e-04	6	108	2	GO:0034388
GeneOntologyCellularComponent	90S preribosome	WDR36 WDR3 WDR12	4.44e-04	29	108	3	GO:0030686
GeneOntologyCellularComponent	PTW/PP1 phosphatase complex	PPP1CA PPP1CC	5.46e-04	7	108	2	GO:0072357
GeneOntologyCellularComponent	nuclear protein-containing complex	RANBP2 ERCC4 WDR36 WWOX RGPD8 POLA1 SMARCAL1 INTS1 XPO4 API5 WDR3 SUPT6H SYNE2 NCOA1 WDR12 MGA RGPD5	6.81e-04	1377	108	17	GO:0140513
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RANBP2 RGPD8	7.26e-04	8	108	2	GO:1990723
GeneOntologyCellularComponent	organelle envelope	RANBP2 RGPD8 POLA1 INTS1 APC XPO4 PTGS2 PPP1CC WDR3 OIT3 TMEM70 SYNE2 THG1L CST3 RARS2 ZBED1 RGPD5	1.08e-03	1435	108	17	GO:0031967
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RANBP2 RGPD8	1.16e-03	10	108	2	GO:0044614
MousePheno	abnormal cell nucleus morphology	PDS5B RANBP2 ERCC4 RGPD8 STAG1 APC SYNE2 ATM	1.57e-05	184	85	8	MP:0003111
MousePheno	aneuploidy	PDS5B RANBP2 RGPD8 STAG1 APC	3.36e-05	61	85	5	MP:0004024
MousePheno	increased sarcoma incidence	RANBP2 WWOX RGPD8 STAG1 APC ATM	3.57e-05	102	85	6	MP:0002032
MousePheno	increased hepatocellular carcinoma incidence	RANBP2 RGPD8 STAG1 APC ATM	6.55e-05	70	85	5	MP:0003331
MousePheno	abnormal intracellular organelle morphology	PDS5B RANBP2 ERCC4 RGPD8 STAG1 APC EPG5 TMEM70 SYNE2 ATM CAMSAP1 CLUH	1.09e-04	546	85	12	MP:0014239
MousePheno	abnormal chromosome morphology	PDS5B RANBP2 RGPD8 STAG1 APC ATM	1.16e-04	126	85	6	MP:0003702
Domain	DM15	LARP1 LARP1B	3.07e-05	2	104	2	SM00684
Domain	DM15	LARP1 LARP1B	3.07e-05	2	104	2	IPR006607
Domain	Ran_BP1	RANBP2 RGPD8 RGPD5	3.56e-05	12	104	3	PF00638
Domain	RANBD1	RANBP2 RGPD8 RGPD5	3.56e-05	12	104	3	PS50196
Domain	RanBD	RANBP2 RGPD8 RGPD5	4.61e-05	13	104	3	SM00160
Domain	Ran_bind_dom	RANBP2 RGPD8 RGPD5	4.61e-05	13	104	3	IPR000156
Domain	STPPase_N	PPP1CA PPP1CC	9.18e-05	3	104	2	IPR031675
Domain	STPPase_N	PPP1CA PPP1CC	9.18e-05	3	104	2	PF16891
Domain	-	POU4F3 ONECUT3 CUX1	4.45e-04	27	104	3	1.10.260.40
Domain	Lambda_DNA-bd_dom	POU4F3 ONECUT3 CUX1	5.52e-04	29	104	3	IPR010982
Domain	RNaseH-like_dom	POLA1 ZNF618 SUPT6H ZBED1	5.94e-04	69	104	4	IPR012337
Domain	ARM-type_fold	PDS5B STAG1 INTS1 APC XPO4 API5 EIF4G2 ATM	6.16e-04	339	104	8	IPR016024
Domain	LA	LARP1 LARP1B	6.33e-04	7	104	2	SM00715
Domain	CUT	ONECUT3 CUX1	6.33e-04	7	104	2	PS51042
Domain	CUT	ONECUT3 CUX1	6.33e-04	7	104	2	PF02376
Domain	HTH_LA	LARP1 LARP1B	6.33e-04	7	104	2	PS50961
Domain	La	LARP1 LARP1B	6.33e-04	7	104	2	PF05383
Domain	CUT_dom	ONECUT3 CUX1	6.33e-04	7	104	2	IPR003350
Domain	Lupus_La_RNA-bd	LARP1 LARP1B	6.33e-04	7	104	2	IPR006630
Domain	CUT	ONECUT3 CUX1	6.33e-04	7	104	2	SM01109
Domain	RuvA_2-like	ERCC4 SUPT6H	1.08e-03	9	104	2	IPR010994
Domain	Grip	RGPD8 RGPD5	1.63e-03	11	104	2	SM00755
Domain	GRIP	RGPD8 RGPD5	1.63e-03	11	104	2	PF01465
Domain	GRIP_dom	RGPD8 RGPD5	1.95e-03	12	104	2	IPR000237
Domain	GRIP	RGPD8 RGPD5	1.95e-03	12	104	2	PS50913
Domain	PP2Ac	PPP1CA PPP1CC	2.30e-03	13	104	2	SM00156
Domain	Ser/Thr-sp_prot-phosphatase	PPP1CA PPP1CC	2.30e-03	13	104	2	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP1CA PPP1CC	2.30e-03	13	104	2	PS00125
Domain	Beta/gamma_crystallin	CRYBG1 CRYBG3	3.08e-03	15	104	2	IPR001064
Domain	CRYSTALLIN_BETA_GAMMA	CRYBG1 CRYBG3	3.08e-03	15	104	2	PS50915
Domain	Crystall	CRYBG1 CRYBG3	3.08e-03	15	104	2	PF00030
Domain	XTALbg	CRYBG1 CRYBG3	3.08e-03	15	104	2	SM00247
Domain	G_crystallin-rel	CRYBG1 CRYBG3	4.43e-03	18	104	2	IPR011024
Domain	Apc4_WD40_dom	WDR36 WDR3	5.47e-03	20	104	2	IPR024977
Domain	ANAPC4_WD40	WDR36 WDR3	5.47e-03	20	104	2	PF12894
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PDS5B RANBP2 WDR36 MYO1D USP11 POLA1 INTS1 LARP1 PPP1CA PPP1CC WDR3 SUPT6H SYNE2 WDR12 ATM CLUH	2.05e-10	653	108	16	22586326
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	RANBP2 MYO1D RBM33 POLA1 APC LARP1 HMMR LARP1B ARHGAP35 PPP1CA PPP1CC FARP1 CAMSAP1 MGA CLUH	7.57e-09	724	108	15	36232890
Pubmed	Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.	RANBP2 RGPD8 RGPD5	1.16e-07	4	108	3	9480752
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	DOCK4 NRG1 POLA1 INTS1 APC ARHGAP35 CIC TBC1D1 ZNF483 EIF4G2 WDR12 MGA CLUH	2.38e-07	689	108	13	36543142
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	RANBP2 USP11 OBSCN FSD2 CMYA5 PPP1CC SUPT6H SYNE2 EIF4G2 DNAJB5 MGA	4.51e-07	497	108	11	23414517
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 GRK7 APC LARP1 LARP1B PRAG1 CIC PPP1CA RUSC2 TBC1D1 SYNE2 CRYBG3 CAMSAP1 PCDH7	4.75e-07	861	108	14	36931259
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	WDR36 USP11 HMMR PPP1CC WDR3 SUPT6H MAP4K5 FARP1 SYNE2 EIF4G2 WDR12 ATM CRYBG3 DNAJB5 NME7 PCDH7 CLUH CUX1	7.40e-07	1487	108	18	33957083
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PDS5B RANBP2 WDR36 WWOX RBM33 LARP1 POU4F3 API5 CIC PPP1CC WDR3 EIF4G2 MGA CUX1	1.59e-06	954	108	14	36373674
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PDS5B RANBP2 WDR36 MYO1D POLA1 TRPC1 LARP1 API5 IDH3B CMYA5 PPP1CA WDR3 SUPT6H EIF4G2 WDR12 ATM CLUH	1.90e-06	1425	108	17	30948266
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	WDR36 STAG1 RBM33 POLA1 HMMR ARHGAP35 CIC CRYBG3 CAMSAP1 CUX1	2.28e-06	472	108	10	38943005
Pubmed	Functional proteomics mapping of a human signaling pathway.	STAG1 CILK1 PPL PPP1CA EPG5 PPP1CC TBC1D1 EIF4G2 GMEB1 CAMSAP1 MGA	2.42e-06	591	108	11	15231748
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	WDR36 WWOX RGPD8 MYO1D RBM33 USP11 IDH3B LARP1B WDR3 TMEM70 SYNE2 THG1L RARS2 WDR12 CRYBG3 CLUH CUX1	3.64e-06	1496	108	17	32877691
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	RANBP2 RGPD8 MYO1D SMARCAL1 LARP1 C4orf54 PPP1CA KRT23 FARP1 CUX1 RGPD5	4.19e-06	626	108	11	33644029
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RANBP2 RBM33 POLA1 API5 IDH3B PPP1CC WDR3 SUPT6H EIF4G2 WDR12 DNAJB5	5.02e-06	638	108	11	33239621
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RANBP2 WWOX RGPD8 APC CIC CRYBG3 CAMSAP1 MGA CUX1	6.58e-06	418	108	9	34709266
Pubmed	Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2).	APC PTGS2	9.55e-06	2	108	2	8945508
Pubmed	Self-promotion? Intimate connections between APC and prostaglandin H synthase-2.	APC PTGS2	9.55e-06	2	108	2	8945503
Pubmed	Ryanodine receptors are part of the myospryn complex in cardiac muscle.	FSD2 CMYA5	9.55e-06	2	108	2	28740084
Pubmed	CDP/Cux stimulates transcription from the DNA polymerase alpha gene promoter.	POLA1 CUX1	9.55e-06	2	108	2	12665598
Pubmed	Cyclooxygenase 2 is up-regulated and localized to macrophages in the intestine of Min mice.	APC PTGS2	9.55e-06	2	108	2	10188882
Pubmed	Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor.	APC PTGS2	9.55e-06	2	108	2	11245490
Pubmed	WWOX modulates the ATR-mediated DNA damage checkpoint response.	WWOX ATM	9.55e-06	2	108	2	26675548
Pubmed	BH-protocadherin-c, a member of the cadherin superfamily, interacts with protein phosphatase 1 alpha through its intracellular domain.	PPP1CA PCDH7	9.55e-06	2	108	2	10571067
Pubmed	The role of cyclooxygenase-2 (COX-2) in two different morphological stages of intestinal polyps in APC(Delta474) knockout mice.	APC PTGS2	9.55e-06	2	108	2	12151354
Pubmed	Spermiogenesis is impaired in mice bearing a targeted mutation in the protein phosphatase 1cgamma gene.	PPP1CA PPP1CC	9.55e-06	2	108	2	9882500
Pubmed	Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in CEA.Tg/MIN mice.	APC PTGS2	9.55e-06	2	108	2	15150127
Pubmed	Correlation between COX-2 and APC expression in left versus right-sided human colon cancer.	APC PTGS2	9.55e-06	2	108	2	21737640
Pubmed	Cooperative effects of matrix metalloproteinase and cyclooxygenase-2 inhibition on intestinal adenoma reduction.	APC PTGS2	9.55e-06	2	108	2	12778076
Pubmed	Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor).	APC HMMR	9.55e-06	2	108	2	14534534
Pubmed	High-density lipoprotein of patients with type 2 diabetes mellitus upregulates cyclooxgenase-2 expression and prostacyclin I-2 release in endothelial cells: relationship with HDL-associated sphingosine-1-phosphate.	MBTPS1 PTGS2	9.55e-06	2	108	2	23360427
Pubmed	USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway.	USP11 PPP1CA	9.55e-06	2	108	2	31521612
Pubmed	Cyclooxygenase-two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor).	APC PTGS2	9.55e-06	2	108	2	11313976
Pubmed	Suppression of polypogenesis in a new mouse strain with a truncated Apc(Delta474) by a novel COX-2 inhibitor, JTE-522.	APC PTGS2	9.55e-06	2	108	2	10783317
Pubmed	PP-1α and PP-1γ display antagonism and differential roles in tumorigenicity of lung cancer cells.	PPP1CA PPP1CC	9.55e-06	2	108	2	23176181
Pubmed	Atm is a negative regulator of intestinal neoplasia.	APC ATM	9.55e-06	2	108	2	17700532
Pubmed	Association of GPIa and COX-2 gene polymorphism with aspirin resistance.	ITGA2 PTGS2	9.55e-06	2	108	2	28948649
Pubmed	The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.	APC PTGS2	9.55e-06	2	108	2	16699180
Pubmed	Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/- mice.	MOGAT2 APC	9.55e-06	2	108	2	39055928
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PDS5B RANBP2 RGPD8 MYO1D STAG1 PCDHGB6 LARP1 PPL PPP1CA PPP1CC KRT23 SYNE2 C4orf51 ATM CUX1 RGPD5	9.79e-06	1442	108	16	35575683
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	LARP1 SUPT6H MAP4K5 EIF4G2	9.88e-06	43	108	4	34672947
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	RANBP2 ERCC4 WDR36 USP11 APC LARP1 WDR3 SUPT6H CAMSAP1	9.91e-06	440	108	9	34244565
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DOCK4 RANBP2 MYO1D APC CILK1 WDR3 TBC1D1 FARP1 EIF4G2 CAMSAP1 NME7 MGA	1.42e-05	853	108	12	28718761
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	RANBP2 USP11 INTS1 LARP1 CIC PPP1CA PPP1CC FARP1 MGA CUX1	1.44e-05	583	108	10	29844126
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	DOCK4 RGPD8 MYO1D RBM33 USP11 APC TWF2 CIC SUPT6H CRYBG3	1.55e-05	588	108	10	38580884
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RANBP2 WDR36 RBM33 INTS1 APC HMMR API5 CIC PPP1CC WDR3 SUPT6H FARP1 EIF4G2 CRYBG1 WDR12 DUSP11	1.55e-05	1497	108	16	31527615
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PDS5B RANBP2 WDR36 USP11 POLA1 SMARCAL1 INTS1 API5 PPP1CA WDR3 SUPT6H EIF4G2 ATM	1.63e-05	1014	108	13	32416067
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	LARP1 API5 LARP1B CMYA5 PPP1CA PPP1CC EIF4G2	1.68e-05	258	108	7	37794589
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	PDS5B NRG1 RBM33 RAPGEF4 OBSCN HMMR PPP1CA WDR12 ATM	2.59e-05	497	108	9	36774506
Pubmed	Mutually exclusive binding of PP1 and RNA to AKAP149 affects the mitochondrial network.	PPP1CA PPP1CC	2.86e-05	3	108	2	19074462
Pubmed	1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.	PPP1CA PPP1CC	2.86e-05	3	108	2	25073485
Pubmed	Alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells.	ITGA2 PTGS2	2.86e-05	3	108	2	16972245
Pubmed	The direct binding of the catalytic subunit of protein phosphatase 1 to the PKR protein kinase is necessary but not sufficient for inactivation and disruption of enzyme dimer formation.	PPP1CA PPP1CC	2.86e-05	3	108	2	12138106
Pubmed	Chromosomal localization of human, rat, and mouse protein phosphatase type 1 beta catalytic subunit genes (PPP1CB) by fluorescence in situ hybridization.	PPP1CA PPP1CC	2.86e-05	3	108	2	7857673
Pubmed	Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.	PPP1CA PPP1CC	2.86e-05	3	108	2	11739654
Pubmed	Characterization of protein phosphatases in mouse oocytes.	PPP1CA PPP1CC	2.86e-05	3	108	2	9882488
Pubmed	Mouse models of gastrointestinal tumors.	APC PTGS2	2.86e-05	3	108	2	16630131
Pubmed	Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice.	APC PTGS2	2.86e-05	3	108	2	10987272
Pubmed	Inhibitory effects of mofezolac, a cyclooxygenase-1 selective inhibitor, on intestinal carcinogenesis.	APC PTGS2	2.86e-05	3	108	2	12189188
Pubmed	Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.	PPP1CA PPP1CC	2.86e-05	3	108	2	21712997
Pubmed	NOM1 targets protein phosphatase I to the nucleolus.	PPP1CA PPP1CC	2.86e-05	3	108	2	17965019
Pubmed	Role of Nesprin-2 and RanBP2 in BICD2-associated brain developmental disorders.	RANBP2 SYNE2	2.86e-05	3	108	2	36930595
Pubmed	Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms.	APC PTGS2	2.86e-05	3	108	2	10204802
Pubmed	Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in Apc(Min)/+ mice.	APC ATM	2.86e-05	3	108	2	11181458
Pubmed	Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1.	PPP1CA PPP1CC	2.86e-05	3	108	2	11588169
Pubmed	Cooperation of cyclooxygenase 1 and cyclooxygenase 2 in intestinal polyposis.	APC PTGS2	2.86e-05	3	108	2	12941808
Pubmed	The cyclooxygenase-2-mediated prostaglandin signaling is causally related to epithelial carcinogenesis.	APC PTGS2	2.86e-05	3	108	2	17546626
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	USP11 APC LARP1 WDR3 SYNE2 NCOA1 MGA CUX1	3.56e-05	398	108	8	35016035
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	PDS5B RANBP2 ERCC4 WDR36 WWOX STAG1 INTS1 API5 PPL PPP1CA	3.73e-05	652	108	10	31180492
Pubmed	Network-Based Combinatorial CRISPR-Cas9 Screens Identify Synergistic Modules in Human Cells.	MBTPS1 APC PTGS2 ATM	4.55e-05	63	108	4	30762338
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RANBP2 RGPD8 ZNF618 RAPGEF4 APC PPP1CA PPP1CC FARP1 SYNE2 CAMSAP1 MGA CUX1	4.63e-05	963	108	12	28671696
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	ZFAND2A TRAPPC11 MYO1D USP11 LARP1 PPP1CA PPP1CC SUPT6H TBC1D1 CUX1	4.69e-05	670	108	10	22990118
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	APC LARP1B ARHGAP35 PPP1CA CRYBG3 CAMSAP1	5.04e-05	209	108	6	36779422
Pubmed	Nucleolar proteome dynamics.	WDR36 API5 PPP1CA PPP1CC WDR3 WDR12 ATM DUSP11	5.11e-05	419	108	8	15635413
Pubmed	Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.	PPP1CA PPP1CC	5.71e-05	4	108	2	23499489
Pubmed	Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein.	PPP1CA PPP1CC	5.71e-05	4	108	2	16131488
Pubmed	Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells.	ITGA2 PTGS2	5.71e-05	4	108	2	20178602
Pubmed	Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.	PPP1CA PPP1CC	5.71e-05	4	108	2	15226296
Pubmed	Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle.	APC ATM	5.71e-05	4	108	2	11943150
Pubmed	Nup358 interacts with APC and plays a role in cell polarization.	RANBP2 APC	5.71e-05	4	108	2	19654215
Pubmed	Nuclear protein phosphatase-1 regulates HIV-1 transcription.	PPP1CA PPP1CC	5.71e-05	4	108	2	12788939
Pubmed	Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.	PPP1CA PPP1CC	5.71e-05	4	108	2	23277204
Pubmed	The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits.	PPP1CA PPP1CC	5.71e-05	4	108	2	12016225
Pubmed	Inhibitor-2 regulates protein phosphatase-1 complexed with NimA-related kinase to induce centrosome separation.	PPP1CA PPP1CC	5.71e-05	4	108	2	12221103
Pubmed	Cyclooxygenase-2 inhibitors down-regulate osteopontin and Nr4A2-new therapeutic targets for colorectal cancers.	APC PTGS2	5.71e-05	4	108	2	19549529
Pubmed	Regulation of ATM and ATR by SMARCAL1 and BRG1.	SMARCAL1 ATM	5.71e-05	4	108	2	30317028
Pubmed	Phosphorylation of protein phosphatase 1 by cyclin-dependent protein kinase 5 during nerve growth factor-induced PC12 cell differentiation.	PPP1CA PPP1CC	5.71e-05	4	108	2	17202132
Pubmed	The mRNA stability factor HuR inhibits microRNA-16 targeting of COX-2.	APC PTGS2	5.71e-05	4	108	2	22049153
Pubmed	ATM regulates ionizing radiation-induced disruption of HDAC1:PP1:Rb complexes.	PPP1CA ATM	5.71e-05	4	108	2	17008050
Pubmed	Synphilin-1A is a phosphoprotein phosphatase 1-interacting protein and affects PPP1 sorting to subcellular compartments.	PPP1CA PPP1CC	5.71e-05	4	108	2	24902662
Pubmed	A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2.	APC PTGS2	5.71e-05	4	108	2	19375854
Pubmed	Characterization of the neuronal targeting protein spinophilin and its interactions with protein phosphatase-1.	PPP1CA PPP1CC	5.71e-05	4	108	2	10194355
Pubmed	WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response.	WWOX ATM	5.71e-05	4	108	2	25331887
Pubmed	NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1.	PPP1CA PPP1CC	5.71e-05	4	108	2	10880350
Pubmed	Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.	PPP1CA PPP1CC	5.71e-05	4	108	2	22768081
Pubmed	DNA methylation markers and early recurrence in stage I lung cancer.	APC CDH13	5.71e-05	4	108	2	18337602
Pubmed	Interaction of inhibitor-2 with the catalytic subunit of type 1 protein phosphatase. Identification of a sequence analogous to the consensus type 1 protein phosphatase-binding motif.	PPP1CA PPP1CC	5.71e-05	4	108	2	10807923
Pubmed	Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.	PPP1CA PPP1CC	5.71e-05	4	108	2	12226088
Pubmed	A vitamin D receptor-Ser/Thr phosphatase-p70 S6 kinase complex and modulation of its enzymatic activities by the ligand.	PPP1CA PPP1CC	5.71e-05	4	108	2	12036952
Pubmed	N-CoR controls differentiation of neural stem cells into astrocytes.	PPP1CA PPP1CC	5.71e-05	4	108	2	12410313
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	PDS5B RANBP2 ERCC4 RBM33 SUPT6H MGA	7.03e-05	222	108	6	37071664
Interaction	SIRT7 interactions	PDS5B RANBP2 WDR36 MYO1D USP11 POLA1 INTS1 LARP1 PPP1CA PPP1CC WDR3 SUPT6H SYNE2 WDR12 ATM CLUH	1.30e-06	744	104	16	int:SIRT7
Interaction	PCNA interactions	PDS5B RANBP2 WWOX USP11 POLA1 OBSCN APC PPP1CA PPP1CC ATM PCDH7 CUX1	9.80e-06	497	104	12	int:PCNA
Interaction	NIN interactions	MYO1D APC CILK1 HMMR WDR3 EIF4G2 DNAJB5 CAMSAP1 NME7 MGA	1.68e-05	359	104	10	int:NIN
Interaction	KRT8 interactions	DOCK4 TRAPPC11 APC PPL KRT23 CRYBG1 CRYBG3 CAMSAP1 PCDH7 CLUH CUX1	1.74e-05	441	104	11	int:KRT8
Interaction	NUP43 interactions	PDS5B RANBP2 WDR36 RGPD8 POLA1 APC LARP1 WDR3 SUPT6H SYNE2 EIF4G2 MGA RGPD5	1.99e-05	625	104	13	int:NUP43
Interaction	MLNR interactions	PDS5B GPR50 INTS1 XPO4 ATM	2.68e-05	68	104	5	int:MLNR
Interaction	ADGRG2 interactions	GPR50 INTS1 ATM	2.84e-05	12	104	3	int:ADGRG2
Interaction	NUP50 interactions	RANBP2 WDR36 RGPD8 RBM33 PPP1CA PPP1CC WDR3 SUPT6H CUX1	6.86e-05	341	104	9	int:NUP50
GeneFamily	Beta-gamma crystallin domain containing	CRYBG1 CRYBG3	4.68e-05	3	72	2	1360
GeneFamily	WD repeat domain containing\|UTPB complex	WDR36 WDR3	2.32e-04	6	72	2	1225
GeneFamily	La ribonucleoprotein domain containing\|RNA binding motif containing	LARP1 LARP1B	3.24e-04	7	72	2	625
GeneFamily	CUT class homeoboxes and pseudogenes	ONECUT3 CUX1	5.53e-04	9	72	2	527
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP1CA PPP1CC	1.19e-03	13	72	2	693
GeneFamily	Fibronectin type III domain containing	OBSCN FSD2 VWA1 CMYA5	3.81e-03	160	72	4	555
Coexpression	DASU_IL6_SIGNALING_SCAR_UP	MYO1D LARP1 CIC PPL	7.87e-06	31	108	4	M292
Coexpression	GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_UP	STAG1 GDE1 MAP4K5 TBC1D1 SYNE2 DNAJB5 CUX1	8.29e-06	175	108	7	M8578
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	DOCK4 PDS5B NRG1 RANBP2 STAG1 TRPC1 APC HMMR ARHGAP35 MAP4K5 SYNE2 NCOA1 CRYBG3 CUX1	1.15e-05	856	108	14	M4500
Coexpression	GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP	MFHAS1 RAPGEF4 POU4F3 PLXND1 CIC TBC1D1 NCOA1	1.97e-05	200	108	7	M9205
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP	INTS1 PTGS2 GDE1 TBC1D1 SYNE2 EIF4G2 ZBED1	1.97e-05	200	108	7	M6090
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	DOCK4 WWOX MYO1D CMYA5 SULF1 TBC1D1 NCOA1	2.86e-05	212	108	7	M39221
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	WDR36 STAG1 APC HMMR API5 FADS3 SUPT6H MAP4K5 EIF4G2 RARS2 CAMSAP1 NME7	4.29e-05	721	108	12	M10237
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRG1 TRPC1 OBSCN KCNT2 FARP1 CRYBG3 PCDH7	2.30e-07	174	108	7	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1D UNC13D ITGA2 PPL FADS3 FARP1 CDH13	3.01e-07	181	108	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYO1D UNC13D ITGA2 PPL FADS3 FARP1 SYNE2	5.70e-07	199	108	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYO1D UNC13D ITGA2 PPL FADS3 FARP1 SYNE2	5.89e-07	200	108	7	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 ZNF618 VWA1 ITGA2 SULF1 CDH13	3.71e-06	170	108	6	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 ZNF618 VWA1 ITGA2 SULF1 CDH13	3.71e-06	170	108	6	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRG1 ZNF618 VWA1 ITGA2 SULF1 CDH13	3.71e-06	170	108	6	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NRG1 TRPC1 FARP1 CRYBG3 CAMSAP1 PCDH7	5.66e-06	183	108	6	5377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP11 SYNE2 CRYBG1 OXNAD1 ATM RGPD5	6.02e-06	185	108	6	847257d232b9993cad50c814fd4ffeef52385295
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1D UNC13D ITGA2 PPL FARP1 CDH13	6.21e-06	186	108	6	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1D UNC13D ITGA2 PPL FARP1 SYNE2	6.40e-06	187	108	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	NRG1 MYO1D UNC13D FADS3 KCNT2 FARP1	6.40e-06	187	108	6	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 NRG1 MYO1D FADS3 KCNT2 FARP1	7.01e-06	190	108	6	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ISLR2 RAPGEF4 ITGA2 THSD1 CRYBG1 CDH13	7.67e-06	193	108	6	01c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D MFHAS1 PRAG1 PPL SYNE2 NEK11	7.90e-06	194	108	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 C12orf56 RAPGEF4 PLXND1 SULF1 CDH13	7.90e-06	194	108	6	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	Epithelial_cells-AT1_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	DOCK4 NRG1 UNC13D PTGS2 FADS3 KCNT2	8.38e-06	196	108	6	6c99d29162848161c1f166a032320f87a5d5a631
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERCC4 CILK1 PLXND1 FARP1 GMEB1 DNAJB5	8.62e-06	197	108	6	789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK4 WWOX MYO1D STAG1 NCOA1 CUX1	8.87e-06	198	108	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	DOCK4 MYO1D MFHAS1 RAPGEF4 VWA1 SYNE2	8.87e-06	198	108	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO1D UNC13D ITGA2 FADS3 FARP1 SYNE2	9.13e-06	199	108	6	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO1D UNC13D ITGA2 FADS3 FARP1 SYNE2	9.40e-06	200	108	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	ZNF618 APC CILK1 SYNE2 PCDH7	2.18e-05	138	108	5	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WWOX ZNF416 TBC1D1 ATM KIR3DL1	6.42e-05	173	108	5	79d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ISLR2 NRG1 ERCC4 MYO1D KCNT2	6.60e-05	174	108	5	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MYO1D HTD2 SYNE2 OXNAD1 RGPD5	6.78e-05	175	108	5	f456d8d958b71f7a942b718605712593d9de1bfd
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	OBSCN CMYA5 C4orf54 PCDH7 CDH13	6.96e-05	176	108	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RANBP2 STAG1 CMYA5 KCNT2 PCDH7	6.96e-05	176	108	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRG1 ITGA2 PPL SULF1 PCDH7	7.15e-05	177	108	5	cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 TRPC1 THSD1 OIT3 MGA	7.54e-05	179	108	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RAPGEF4 VWA1 PLXND1 THSD1	7.54e-05	179	108	5	8f9e538c822940785130297712b75131812a4603
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RAPGEF4 VWA1 PLXND1 CDH13	7.74e-05	180	108	5	16728b9a1c52097e3a460534be71a476ecc54f0f
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UNC13D ITGA2 FADS3 FARP1 SYNE2	8.59e-05	184	108	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	OBSCN SYNE2 OXNAD1 ATM RGPD5	8.59e-05	184	108	5	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	NRG1 UNC13D FADS3 KCNT2 FARP1	8.59e-05	184	108	5	561592edc3083fad41b91811151b442207c65dd9
ToppCell	mild-Myeloid-Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	DOCK4 PTGS2 KRT23 DPEP2 NCOA1	8.59e-05	184	108	5	1a0e8b20b3ac8416d05c2d5934ab4ac80be4cce5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RAPGEF4 VWA1 PLXND1 CDH13	8.59e-05	184	108	5	a12a6a481e78adc62da1904431f62b119f70b15f
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NRG1 MYO1D FADS3 KCNT2 FARP1	8.81e-05	185	108	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	MYO1D ITGA2 PTGS2 KCNT2 FARP1	8.81e-05	185	108	5	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP11 PRAG1 OIT3 TBC1D1 CDH13	8.81e-05	185	108	5	efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell	droplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP11 PRAG1 OIT3 TBC1D1 CDH13	8.81e-05	185	108	5	642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXND1 MAP4K5 WDR12 TUBE1 CUX1	8.81e-05	185	108	5	dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PLXND1 FADS3 SULF1 USP27X CDH13	9.04e-05	186	108	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 MYO1D MFHAS1 PRAG1 PPL	9.27e-05	187	108	5	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 POLA1 RAPGEF4 PLXND1 CDH13	9.27e-05	187	108	5	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 MYO1D MFHAS1 PRAG1 PPL	9.27e-05	187	108	5	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NRG1 MYO1D MFHAS1 PRAG1 PPL	9.27e-05	187	108	5	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ISLR2 ITGA2 THSD1 OIT3 CRYBG3	9.27e-05	187	108	5	d9d10ed7c905778a29a0dc3ced3eef02a6b1de5c
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ISLR2 ITGA2 PLXND1 THSD1 OIT3	9.27e-05	187	108	5	25efb82afe863a853ecdd781ad89026c993aaa67
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	9.27e-05	187	108	5	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 THSD1 PTGS2 KCNT2 CDH13	9.27e-05	187	108	5	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	9.50e-05	188	108	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ISLR2 RUSC2 ZNF469 SULF1 FARP1	9.50e-05	188	108	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO1D ITGA2 PRAG1 PTGS2 PPL	9.50e-05	188	108	5	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXND1 MAP4K5 WDR12 TUBE1 CUX1	9.50e-05	188	108	5	59b71462338a7efbacf46577cb07e9db3363afee
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	9.74e-05	189	108	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	9.74e-05	189	108	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NRG1 RAPGEF4 KCNT2 PCDH7 CDH13	9.74e-05	189	108	5	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 C12orf56 PLXND1 SULF1 CDH13	9.74e-05	189	108	5	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA2 HMMR PLXND1 THSD1 OIT3	9.74e-05	189	108	5	1d660bceee449aebf12fc9af4c74af246837b27a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	NRG1 MYO1D UNC13D FADS3 FARP1	9.74e-05	189	108	5	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RAPGEF4 PLXND1 SULF1 CDH13	9.99e-05	190	108	5	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	9.99e-05	190	108	5	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 PLXND1 PTGS2 SULF1 CDH13	9.99e-05	190	108	5	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF618 SYNE2 C4orf51 PCDH7 CDH13	9.99e-05	190	108	5	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	T_cells-Effector_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	MYO1D MFHAS1 PLXND1 ARHGAP35 OXNAD1	9.99e-05	190	108	5	1af91fe0ee2c924e12f4db93c793e7af475d8f80
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	9.99e-05	190	108	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	1.02e-04	191	108	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 C12orf56 RAPGEF4 SULF1 CDH13	1.02e-04	191	108	5	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE2 CRYBG1 OXNAD1 ATM RGPD5	1.02e-04	191	108	5	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP11 SYNE2 OXNAD1 ATM RGPD5	1.02e-04	191	108	5	696921a4f160b6b55698652488ed781e855e5e51
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	OBSCN FSD2 CMYA5 PCDH7 CDH13	1.05e-04	192	108	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	MFHAS1 ZNF618 ITGA2 CRYBG1 PCDH7	1.05e-04	192	108	5	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	WWOX STAG1 FARP1 SYNE2 CUX1	1.05e-04	192	108	5	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	COPD-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	DOCK4 MYO1D ITGA2 PCDH7 CDH13	1.05e-04	192	108	5	62904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DOCK4 WWOX RGPD8 STAG1 CUX1	1.07e-04	193	108	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ITGA2 THSD1 OIT3 CRYBG1 CDH13	1.07e-04	193	108	5	d338a7c0585b69947c37f44aa0381619493e31ea
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MFHAS1 PRAG1 PPL SYNE2 NEK11	1.07e-04	193	108	5	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK4 MYO1D RAPGEF4 ITGA2 THSD1	1.07e-04	193	108	5	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	POLA1 PTGS2 GDE1 EIF4G2 GMEB1	1.07e-04	193	108	5	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	DOCK4 MYO1D ITGA2 PCDH7 CDH13	1.07e-04	193	108	5	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 C12orf56 PLXND1 SULF1 CDH13	1.07e-04	193	108	5	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MFHAS1 PRAG1 PPL SYNE2 NEK11	1.07e-04	193	108	5	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ISLR2 RAPGEF4 ITGA2 THSD1 CRYBG1	1.10e-04	194	108	5	3c31ac44e8cf4eca3ba7b8bfc05ad3e96a970956
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RAPGEF4 VWA1 PLXND1 THSD1	1.10e-04	194	108	5	74a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RAPGEF4 ITGA2 THSD1 CRYBG1 CDH13	1.10e-04	194	108	5	32ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 TBC1D1 PCDH7 CDH13	1.10e-04	194	108	5	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 TBC1D1 PCDH7 CDH13	1.10e-04	194	108	5	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ITGA2 PLXND1 THSD1 OIT3 CDH13	1.10e-04	194	108	5	eb279e0d922de921343f0ae032a809f837d915b3
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RAPGEF4 ITGA2 THSD1 CRYBG1 CDH13	1.10e-04	194	108	5	53a5e8863d79a052dff0758f389be5ac3883c721
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 SULF1 PCDH7 CDH13	1.10e-04	194	108	5	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	facs-Thymus-nan-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBTPS1 PLXND1 EIF4G2 TUBE1 CUX1	1.13e-04	195	108	5	79114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCell	AT1_cells\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 UNC13D PTGS2 FADS3 KCNT2	1.13e-04	195	108	5	792d6a49b0a875a00569071183d195287a9925c5
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK4 RAPGEF4 PRAG1 SYNE2 CDH13	1.13e-04	195	108	5	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK4 WWOX MYO1D STAG1 NCOA1	1.16e-04	196	108	5	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 SULF1 PCDH7 CDH13	1.16e-04	196	108	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 SULF1 PCDH7 CDH13	1.16e-04	196	108	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	saliva\|World / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK4 VWA1 PTGS2 PPL KRT23	1.18e-04	197	108	5	0a7457dbf798f6071ada3b2b2be231ad13bdb660
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NRG1 UNC13D FADS3 KCNT2 FARP1	1.18e-04	197	108	5	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RAPGEF4 VWA1 PLXND1 CDH13	1.18e-04	197	108	5	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
Drug	Chlorine trioxide	WWOX ITGA2 CUX1	1.89e-06	6	105	3	CID000139646
Drug	genistein; Down 200; 10uM; MCF7; HT_HG-U133A	PDS5B WWOX MFHAS1 INTS1 SUPT6H FARP1 NCOA1 NEK11	3.57e-06	196	105	8	6994_DN
Drug	Flumethasone [2135-17-3]; Down 200; 9.8uM; MCF7; HT_HG-U133A	WWOX TRPC1 CILK1 TWF2 SULF1 SUPT6H TMEM70 NCOA1	4.00e-06	199	105	8	3410_DN
Disease	Malignant neoplasm of breast	NRG1 WWOX PCDHGB6 SMARCAL1 OBSCN HMMR PTGS2 CIC EPG5 KCNT2 FARP1 SYNE2 NCOA1 ATM CUX1	4.83e-06	1074	103	15	C0006142
Disease	cancer (implicated_via_orthology)	ERCC4 WWOX PPP1CA PPP1CC THG1L ATM CUX1	4.45e-05	268	103	7	DOID:162 (implicated_via_orthology)
Disease	Prostatic Neoplasms	MBTPS1 APC UNC13D PTGS2 PPL NCOA1 ATM ZBED1 MGA CDH13	6.05e-05	616	103	10	C0033578
Disease	Malignant neoplasm of prostate	MBTPS1 APC UNC13D PTGS2 PPL NCOA1 ATM ZBED1 MGA CDH13	6.05e-05	616	103	10	C0376358
Disease	lysophosphatidylcholine measurement	WWOX FADS3 MAP4K5 MGA	6.69e-05	62	103	4	EFO_0010224
Disease	Liver carcinoma	MBTPS1 MOGAT2 APC HMMR PTGS2 OIT3 TMEM70 ATM CDH13	7.31e-05	507	103	9	C2239176
Disease	Intestinal Polyps	APC PTGS2	1.20e-04	5	103	2	C0021846
Disease	heart rate	ERCC4 WWOX RAPGEF4 PPP1CC TBC1D1 CUX1	1.42e-04	225	103	6	EFO_0004326
Disease	peripheral neuropathy, response to bortezomib	CMYA5 CDH13	1.79e-04	6	103	2	EFO_0003100, EFO_0007808
Disease	creatinine measurement	NRG1 STAG1 USP11 GRK7 TRPC1 OBSCN FSD2 PTGS2 MAP4K5 CUX1 CDH13 DUSP11	1.85e-04	995	103	12	EFO_0004518
Disease	Glioma	APC PTGS2 CIC ATM	2.50e-04	87	103	4	C0017638
Disease	urate measurement, bone density	ERCC4 WWOX ZNF618 ENTPD4 PPL SULF1 MAP4K5 EIF4G2 CDH13	3.24e-04	619	103	9	EFO_0003923, EFO_0004531
Disease	Adenocarcinoma of large intestine	APC ATM CUX1 NEK11	3.64e-04	96	103	4	C1319315
Disease	Bell's palsy	POU4F3 FARP1 EIF4G2 MGA	4.58e-04	102	103	4	EFO_0007167
Disease	level of Phosphatidylcholine (18:0_22:5) in blood serum	FADS3 MAP4K5	5.33e-04	10	103	2	OBA_2045096
Disease	level of Ceramide (d40:1) in blood serum	MAP4K5 SYNE2	6.50e-04	11	103	2	OBA_2045185
Disease	pancreatic cancer (is_implicated_in)	ERCC4 APC PTGS2 ATM	6.51e-04	112	103	4	DOID:1793 (is_implicated_in)
Disease	Fibrosis	PTGS2 THG1L ATM	7.19e-04	50	103	3	C0016059
Disease	Cirrhosis	PTGS2 THG1L ATM	7.19e-04	50	103	3	C1623038
Disease	retinal drusen	ITGA2 LARP1B KCNT2	7.62e-04	51	103	3	EFO_1001155
Disease	endometrial carcinoma (is_implicated_in)	APC CDH13	7.78e-04	12	103	2	DOID:2871 (is_implicated_in)
Disease	Secondary Open Angle Glaucoma	WDR36 PTGS2	7.78e-04	12	103	2	C0271148
Disease	Glaucoma, Open-Angle	WDR36 PTGS2	7.78e-04	12	103	2	C0017612
Disease	substance-related disorder	C4orf54 NT5C1A MAP4K5	8.06e-04	52	103	3	MONDO_0002494
Disease	glucose metabolism measurement, age-related hearing impairment	WWOX MYO1D ZNF469	8.06e-04	52	103	3	EFO_0005782, EFO_0009367
Disease	Glaucoma, Primary Open Angle	WDR36 PTGS2	9.18e-04	13	103	2	C0339573
Disease	level of Phosphatidylcholine (16:0_18:3) in blood serum	FADS3 MAP4K5	9.18e-04	13	103	2	OBA_2045072
Disease	Squamous cell carcinoma	ERCC4 WWOX PTGS2 ATM	9.53e-04	124	103	4	C0007137
Disease	level of Phosphatidylcholine (18:1_20:2) in blood serum	MOGAT2 FADS3	1.07e-03	14	103	2	OBA_2045102
Disease	Malignant Neoplasms	APC PTGS2 ATM CUX1	1.07e-03	128	103	4	C0006826
Disease	schizophrenia (biomarker_via_orthology)	NRG1 PTGS2	1.23e-03	15	103	2	DOID:5419 (biomarker_via_orthology)
Disease	glucose homeostasis measurement, glucose effectiveness measurement	MAP4K5 CDH13	1.23e-03	15	103	2	EFO_0006833, EFO_0006896
Disease	schizophrenia, intelligence, self reported educational attainment	ERCC4 CYP2D7 STAG1 RAPGEF4 FARP1 CDH13	1.37e-03	346	103	6	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	Barrett Epithelium	PTGS2 CDH13	1.40e-03	16	103	2	C1258085
Disease	Polyposis, Adenomatous Intestinal	APC PTGS2	1.40e-03	16	103	2	C2713442
Disease	Familial Intestinal Polyposis	APC PTGS2	1.40e-03	16	103	2	C2713443
Disease	Barrett Esophagus	PTGS2 CDH13	1.40e-03	16	103	2	C0004763
Disease	Benign neoplasm of stomach	APC ATM	1.59e-03	17	103	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	APC ATM	1.59e-03	17	103	2	C0496905
Disease	diabetic neuropathy (biomarker_via_orthology)	NRG1 PTGS2	1.59e-03	17	103	2	DOID:9743 (biomarker_via_orthology)
Disease	Carcinoma in situ of stomach	APC ATM	1.59e-03	17	103	2	C0154060
Disease	Alzheimer disease, brain volume measurement	PDS5B FARP1	1.59e-03	17	103	2	EFO_0006930, MONDO_0004975
Disease	Adenomatous Polyposis Coli	APC PTGS2	1.59e-03	17	103	2	C0032580
Disease	obesity	NRG1 WWOX CMYA5 PRAG1 EIF4G2	1.59e-03	241	103	5	EFO_0001073
Disease	Oral Submucous Fibrosis	PTGS2 CST3	1.78e-03	18	103	2	C0029172
Disease	Gastric ulcer	NRG1 PTGS2	1.78e-03	18	103	2	C0038358
Disease	melanoma	ERCC4 PTGS2 CRYBG1 ATM CUX1	1.81e-03	248	103	5	C0025202
Disease	JT interval	OBSCN DNAJB5 NME7 CLUH CUX1	1.81e-03	248	103	5	EFO_0007885
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	CILK1 PTGS2 SYNE2 ATM	1.83e-03	148	103	4	C0279702
Disease	Cardiomyopathies, Primary	PTGS2 EPG5 TMEM70	1.83e-03	69	103	3	C0033141
Disease	Myocardial Diseases, Secondary	PTGS2 EPG5 TMEM70	1.83e-03	69	103	3	C0036529
Disease	Alzheimer's disease (is_marker_for)	NRG1 APC PTGS2 CST3 ATM	2.11e-03	257	103	5	DOID:10652 (is_marker_for)
Disease	nucleotide measurement	ITGA2 SULF1 SYNE2	2.15e-03	73	103	3	EFO_0010513
Disease	BREAST CANCER	HMMR ATM	2.43e-03	21	103	2	114480
Disease	Stomach Carcinoma	APC ATM	2.43e-03	21	103	2	C0699791
Disease	Mammary Carcinoma, Human	NRG1 WWOX PCDHGB6 HMMR PTGS2 NCOA1 ATM	2.47e-03	525	103	7	C4704874
Disease	Mammary Neoplasms, Human	NRG1 WWOX PCDHGB6 HMMR PTGS2 NCOA1 ATM	2.47e-03	525	103	7	C1257931
Disease	Disproportionate short stature	SMARCAL1 CILK1 SULF1	2.51e-03	77	103	3	C0878659
Disease	Mammary Neoplasms	NRG1 WWOX PCDHGB6 HMMR PTGS2 NCOA1 ATM	2.53e-03	527	103	7	C1458155
Disease	Esophageal Neoplasms	WWOX PTGS2 CDH13	2.60e-03	78	103	3	C0014859
Disease	Malignant neoplasm of esophagus	WWOX PTGS2 CDH13	2.60e-03	78	103	3	C0546837
Disease	electrocardiography	NRG1 MFHAS1 GRK7 OBSCN XPO4 NME7 CDH13	2.61e-03	530	103	7	EFO_0004327
Disease	Breast Carcinoma	NRG1 WWOX PCDHGB6 HMMR PTGS2 NCOA1 ATM	2.83e-03	538	103	7	C0678222
Disease	Immunologic Deficiency Syndromes	EPG5 ATM	2.91e-03	23	103	2	C0021051
Disease	level of Phosphatidylinositol (18:0_20:4) in blood serum	FADS3 MAP4K5	2.91e-03	23	103	2	OBA_2045158
Disease	mean platelet volume	PDS5B GLOD5 PCDHGB6 POLA1 UNC13D ITGA2 PLXND1 MAP4K5 SYNE2 CUX1	3.02e-03	1020	103	10	EFO_0004584
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	CYP2D7 CUX1	3.17e-03	24	103	2	EFO_0003761, EFO_0005658
Disease	phosphatidylethanolamine measurement	WWOX CMYA5 FADS3 MAP4K5	3.21e-03	173	103	4	EFO_0010228
Disease	phosphatidylcholine measurement	MOGAT2 FADS3 MAP4K5 SYNE2 NCOA1	3.24e-03	284	103	5	EFO_0010226

Protein segments in the cluster

Peptide	Gene	Start	Entry
DFHHAASKALRVPAE	EPG5	1361	Q9HCE0
DIVFVLKDKPHAHFR	DNAJB5	241	O75953
KPHFHGQAKEFSEHI	CRYBG3	2486	Q68DQ2
DRFFEHEKAHENKPL	NT5C1A	231	Q9BXI3
KFFKHFPELADSAIN	API5	51	Q9BZZ5
LHPNTDPFKFEIHKQ	CDH13	611	P55290
FAQQHKAKDPVALHE	CAMSAP1	981	Q5T5Y3
HAFNQSAELKPHVFE	ISLR2	471	Q6UXK2
IDPLFKHFHSVDIQA	RANBP2	626	P49792
AIAKFKEPAHALAFQ	RBM33	1136	Q96EV2
KEPAHALAFQQKFHR	RBM33	1141	Q96EV2
LHLASDFFLKHPDKD	PDS5B	61	Q9NTI5
IDPLFKHFHSVDIQA	RGPD5	626	Q99666
IDPLFKHFHSVDIQA	RGPD8	626	O14715
LREKKFDHHPQQFSS	NRG1	486	Q02297
VNDHAPQFDKKEIHL	PCDHGB6	126	Q9Y5F9
KFQHPSHELLKENGF	LARP1	871	Q6PKG0
VFDTGLSEKHPHFKN	MBTPS1	216	Q14703
VKFNDQLISPKHFVH	GMEB1	121	Q9Y692
TKHFQRKAAHRDPVF	MGA	1096	Q8IWI9
FEDSPALKEHVFHNL	MFHAS1	716	Q9Y4C4
SFLQKHADPLHDLSF	INTS1	1976	Q8N201
NLHEVGKEFEPKAAH	GLOD5	81	A6NK44
PASVHFKADSVHFKG	GPR50	441	Q13585
VHFKGDSVHFKPDSV	GPR50	451	Q13585
KFADHLHKFHENDNG	CUX1	656	Q13948
EHFFLHKEGISKDPS	KIR3DL1	151	P43629
LHLNEDFAKHTKFGN	HTD2	66	P86397
AKEQHKLGFVSAFLH	PLXND1	271	Q9Y4D7
HLAKHFQVPVFKFVG	OIT3	471	Q8WWZ8
KKDHEDFFTPQQHDK	PCDH7	916	O60245
FHNEVKAIGPHLAKD	PPL	171	O60437
KPAFVKADHADEVRF	CES5A	446	Q6NT32
LDHPAIVKFHASFVE	NEK11	86	Q8NG66
KHHVPSDFNVNVKVD	KRT23	216	Q9C075
FTHQFFKTDHKRGPA	PTGS2	191	P35354
KPENKFHIKFADHVV	KCNT2	421	Q6UVM3
SFKPVMQKFLHDHVD	EIF4G2	811	P78344
KTSHGHLIFPKQAFD	ITGA2	411	P17301
AALVHHSFALDKAAP	POLA1	561	P09884
LSFHLHVAEPKAVFA	OBSCN	1521	Q5VST9
FFSKQLENNHVPKEH	OXNAD1	291	Q96HP4
FHHESKENFALKTPL	HMMR	691	O75330
FEAHKLKFNIPADQH	MOGAT2	316	Q3SYC2
TFGAEVVAKFLHKHD	PPP1CA	226	P62136
FFQSVPECEHHQKDK	ATM	626	Q13315
IFFDVKGHAHKATEA	GDE1	171	Q9NZC3
FKAAAVPVEFQEHHL	IDH3B	71	O43837
INLLQDSKFHHFKPV	DOCK4	646	Q8N1I0
HQVPDDETIFKFKHA	DUSP11	166	O75319
PNFEPLHKFHTNFLK	FARP1	586	Q9Y4F1
HRFNEGVHPAFALEK	CMYA5	4036	Q8N3K9
DLHAHKLRVDPVNFK	HBA1;	86	P69905
ADHFDHIKAVIGSKF	DPEP2	331	Q9H4A9
HEDHLEKVFDPKVFT	CRYBG1	736	Q9Y4K1
DDPRKHHFFKTINFP	GRK7	446	Q8WTQ7
PAAAVAQDHAKKFIA	C4orf54	571	D6RIA3
QHHAKPNIFHKDPDV	FADS3	221	Q9Y5Q0
FHDQPHLKRKAFCSF	CST3	111	P01034
PFKKSFDVKHGVAHQ	C4orf51	111	C9J302
KEALDFHVDHQSRPF	NME7	131	Q9Y5B8
IFVLQKKHDFPVQAH	CPHXL	91	A0A1W2PPM1
FPKFQHPSHELLKEN	LARP1B	691	Q659C4
IALFEHAKKPGLAAH	MAP4K5	581	Q9Y4K4
PLAAVADKFHQHAAA	ONECUT3	116	O60422
PFVFQHHFPKQLAKA	RUSC2	696	Q8N2Y8
FSSPNVAKKFHVGHL	RARS2	131	Q5T160
VKAFEKFHPNLLHQI	RAPGEF4	41	Q8WZA2
KEIFDFSPEEHLKHG	SYNE2	3916	Q8WXH0
HVGDHAEFVKNLLPK	NCOA1	161	Q15788
LLNFAAEHVPRAKHK	ENTPD4	156	Q9Y227
PIRAFQKVFDEHKEH	FSD2	186	A1L4K1
EKFLVFAHHKVVLDA	SMARCAL1	726	Q9NZC9
AAVDIVSHGKNHPFK	POU4F3	61	Q15319
QPQHKLEIFHPFFKD	ARHGAP35	926	Q9NRY4
STDDKHLKFQPHFGQ	APC	1081	P25054
DLAFQVKEAHFKAHP	CIC	251	Q96RK0
IHKHGFFHRDLKPEN	CILK1	116	Q9UPZ9
SVRKFLFPFHHTKAN	C12orf56	121	Q8IXR9
PVVKHVNPKASDAFH	CLUH	966	O75153
EHFLDAQGHFVKPEA	CYP2D7	436	A0A087X1C5
AHPSFHNINFKQAEK	SUPT6H	1331	Q7KZ85
ALKVVAHNKFHDFAD	TRPC1	471	P48995
AASAPAEKHLHFVDV	VWA1	181	Q6PCB0
AHKCPFAFQKDVHVP	ZFAND2A	41	Q8N6M9
KLPVVACFHFKRFEH	USP27X	301	A6NNY8
HLFLEALKENFKVHP	ZNF618	786	Q5T7W0
ALKENFKVHPAHKVA	ZNF618	791	Q5T7W0
LTLVQDDKHFHKGFF	XPO4	411	Q9C0E2
KAKFHAPSFHVDVPV	TRAPPC11	591	Q7Z392
AFSKDHQLLRADPKH	TUBE1	326	Q9UJT0
NFHRFAEKHNFAKPN	THG1L	61	Q9NWX6
GAHLFPEKLEHFQEA	THSD1	701	Q9NS62
KFLAEQFHLKHQFPS	TBC1D1	811	Q86TI0
QHFAEAFKAKNVPLH	WWOX	191	Q9NZC7
HKKLFSRHDPQAEEA	STAG1	436	Q8WVM7
AFHPVSFPEEKAVHK	PRAG1	176	Q86YV5
TFGAEVVAKFLHKHD	PPP1CC	226	P36873
APDHFQEDHLLQKEK	ZNF469	3606	Q96JG9
FHQDQKHHSAEKPLE	ZNF416	136	Q9BWM5
PFGHNFKETSDLIKH	ZNF483	306	Q8TF39
FHVAVNSFLEQHKPE	ERCC4	196	Q92889
EFHKHVEFDFLIKGQ	WDR12	46	Q9GZL7
FVPKSHLFFTAGKDH	WDR3	641	Q9UNX4
HLEKNHPEEFCEFVK	ZBED1	66	O96006
HQNDVKIPDAKHVFT	TMEM70	196	Q9BUB7
KSHLHPFKEAAQEVD	SULF1	696	Q8IWU6
SIVPHVFKNKVGHFA	USP11	376	P51784
HKKDLHPLFDETFEF	UNC13D	971	Q70J99
EVHPKQHAFKQAFAK	TWF2	311	Q6IBS0
HTFKGHKAEIHFLQP	WDR36	156	Q8NI36
FLEALNSKLGKHAHF	MYO1D	471	O94832