Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	RA	ARAP3 RGL2 ARAP1	5.30e-05	36	38	3	PF00788
Domain	RA	ARAP3 RGL2 ARAP1	5.76e-05	37	38	3	PS50200
Domain	RA_dom	ARAP3 RGL2 ARAP1	7.29e-05	40	38	3	IPR000159
Domain	Homeodomain-like	ESX1 RCOR3 TIGD5 UTF1 PROX2	5.34e-04	332	38	5	IPR009057
Domain	PH	PLEKHA4 ARAP3 PLEKHO2 ARAP1	1.17e-03	229	38	4	PF00169
Domain	ArfGap	ARAP3 ARAP1	1.58e-03	29	38	2	SM00105
Domain	ARFGAP	ARAP3 ARAP1	1.58e-03	29	38	2	PS50115
Domain	ArfGAP	ARAP3 ARAP1	1.58e-03	29	38	2	IPR001164
Domain	ArfGap	ARAP3 ARAP1	1.58e-03	29	38	2	PF01412
Domain	PH	PLEKHA4 ARAP3 PLEKHO2 ARAP1	2.38e-03	278	38	4	SM00233
Domain	PH_DOMAIN	PLEKHA4 ARAP3 PLEKHO2 ARAP1	2.41e-03	279	38	4	PS50003
Domain	PH_domain	PLEKHA4 ARAP3 PLEKHO2 ARAP1	2.44e-03	280	38	4	IPR001849
Domain	RhoGAP	ARAP3 ARAP1	7.06e-03	62	38	2	SM00324
Domain	RhoGAP	ARAP3 ARAP1	7.28e-03	63	38	2	PF00620
Domain	RHOGAP	ARAP3 ARAP1	7.51e-03	64	38	2	PS50238
Domain	RhoGAP_dom	ARAP3 ARAP1	7.51e-03	64	38	2	IPR000198
Domain	-	ARAP3 ARAP1	7.51e-03	64	38	2	1.10.555.10
Domain	-	PLEKHA4 ARAP3 PLEKHO2 ARAP1	7.96e-03	391	38	4	2.30.29.30
Domain	-	ARID1B APC2 IFRD2	1.03e-02	222	38	3	1.25.10.10
Pubmed	An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation.	SRRM1 RNPS1	1.22e-05	5	39	2	12944400
Pubmed	The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions.	SRRM1 RNPS1	1.22e-05	5	39	2	11118221
Pubmed	Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.	ARAP3 ARAP1	1.83e-05	6	39	2	11804589
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ADAMTS12 SRRM1 YBX2 MAP7D1 RBMXL2 ITIH6 RNPS1 CTAGE1 MYLK2	2.43e-05	1442	39	9	35575683
Pubmed	PI3K signaling through the dual GTPase-activating protein ARAP3 is essential for developmental angiogenesis.	ARAP3 ARAP1	2.56e-05	7	39	2	20978237
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MICAL3 ARAP3 TEP1 RGL2 PLEKHO2 ANO8 ARAP1 IFRD2	2.59e-05	1105	39	8	35748872
Pubmed	The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction.	SRRM1 RNPS1	3.42e-05	8	39	2	9933612
Pubmed	The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling.	SRRM1 RNPS1	4.39e-05	9	39	2	12093754
Pubmed	Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1.	SRRM1 RNPS1	5.48e-05	10	39	2	11546874
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SRRM1 RCOR3 MAP7D1 ARID1B TIGD5 TEP1 RNPS1	2.15e-04	1116	39	7	31753913
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	ETV3 RCOR3 ARID1B RNPS1	2.29e-04	268	39	4	33640491
Pubmed	Proteomic profiling of Myc-associated proteins.	ETV3 RCOR3 MAP7D1	2.88e-04	114	39	3	21150319
Pubmed	The sequence of the human genome.	MICAL3 MEF2B CLEC2L CTAGE1 DENND4B	5.45e-04	603	39	5	11181995
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	CBLL1 SRRM1 MAP7D1 RNPS1	7.05e-04	361	39	4	30344098
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	ETV3 SRRM1 MAP7D1 RNPS1	7.73e-04	370	39	4	22922362
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	RCOR3 MAP7D1 UTF1	1.04e-03	177	39	3	26206133
Cytoband	5q31.3	ARAP3 FCHSD1	4.58e-04	36	40	2	5q31.3
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHA4 ARAP3 PLEKHO2 ARAP1	4.05e-04	206	31	4	682
GeneFamily	ArfGAPs	ARAP3 ARAP1	1.45e-03	33	31	2	395
GeneFamily	Sterile alpha motif domain containing	ARAP3 ARAP1	9.94e-03	88	31	2	760
Drug	NSC329495	ABCC11 ACHE	3.83e-04	17	39	2	CID000003978
Drug	2 MAC	NANOS1 ACHE	6.46e-04	22	39	2	CID000005624
Drug	HF-2035	NANOS1 MYLK2	8.37e-04	25	39	2	CID006439511
Drug	Clorocruoro Hem	NANOS1 ACHE MYLK2	1.22e-03	123	39	3	CID003518809
Drug	dyspropterin	NANOS1 AKR7A2	1.29e-03	31	39	2	CID000128973
Drug	AC1L1I2J	SRRM1 NANOS1	1.37e-03	32	39	2	CID000004395

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPMGPRRFLPPEPKQ	ACHE	71	P22303
RMAPVPPGPRMAPVP	ESX1	281	Q8N693
PMARVPPGPPMARVP	ESX1	326	Q8N693
PPPEARALAMSRPPP	AKR7A2	21	O43488
HPRPPQPPRPLRTGM	ARAP3	386	Q8WWN8
PRDVPGPPRAPFAMR	CTAGE1	706	Q96RT6
EPPPPPRPMLRFYLI	ADGRA3	866	Q8IWK6
PRTFPRYPGLMVPPL	ETV3	316	P41162
SKMEIPPRRRPPPPL	ARID1B	1906	Q8NFD5
RPFSPRRPPLRRMPS	CBY3	86	A6NI87
PVPPPTSRPRMLTTP	ADAMTS12	1021	P58397
RSRSPAPPPPMPLPR	ANO8	1126	Q9HCE9
PPPPLIRPANSMPPR	RCOR3	451	Q9P2K3
VPPPLPATWMRPPRE	MICAL3	1486	Q7RTP6
PRRGRAPPPMALVPS	NANOS1	11	Q8WY41
PPPPAPFPHRMVELR	MYLK2	261	Q9H1R3
MIPFRPKPRFPAPQP	ABCC11	71	Q96J66
PRPRLYPAAPAMPSP	MEF2B	126	Q02080
RAPPAELSMAPPPPR	CBLL1	261	Q75N03
SPRYPIPPRMTPKPC	PROX2	311	Q3B8N5
RLRPMRPPPPPPAKA	FCHSD1	666	Q86WN1
MPPRRCRPFPPVQLL	IL1RL2	536	Q9HB29
PFMQRPARRGPPPLA	APC2	1931	O95996
PRPPRPVPGMPRARK	IFRD2	56	Q12894
PTPPAMGPRDARPPR	MAP7D1	96	Q3KQU3
MPQTPLPPRPDRPRP	ITIH6	881	Q6UXX5
LPPDLPPPARRSPMD	DENND4B	1081	O75064
PGLAPMLAPPPRRTP	SALL3	1096	Q9BXA9
PLDPLVPMPPPRSSR	RGL2	76	O15211
PPRRFSPPRRMLPPP	RNPS1	246	Q15287
SPPRRMLPPPPMWRR	RNPS1	251	Q15287
PPRPPGTRASMVLLP	PLEKHA4	336	Q9H4M7
PMRREPPARAQPAPP	PRR20G	51	P0DPQ3
PSRAPMPMKRGPPPR	RBMXL2	141	O75526
MPMKRGPPPRRVGPP	RBMXL2	146	O75526
PAPAPRPTPRPVPMK	ARAP1	71	Q96P48
MEPAREPPSRARPPP	CLEC2L	1	P0C7M8
RRFIPRPPSVAPPPM	YBX2	181	Q9Y2T7
PRRPPRSPGMEPPFS	TEP1	391	Q99973
PSPRRRTPPRRMPPP	SRRM1	321	Q8IYB3
SPMTPPRASPRTPPR	nan	256	Q9UF83
PRETPRPLMPPTKPF	PLEKHO2	196	Q8TD55
PPPAPGPRPRVAVKM	TIGD5	36	Q53EQ6
MLLRPRRPPPLAPPA	UTF1	1	Q5T230