Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	1.36e-06	5	104	3	GO:0030156
GeneOntologyCellularComponent	photoreceptor connecting cilium	WHRN CEP290 PCDHB13 PCDHB8 SPTBN5 RP1L1	1.28e-07	48	103	6	GO:0032391
GeneOntologyCellularComponent	ciliary transition zone	WHRN CEP290 PCDHB13 PCDHB8 SPTBN5 RP1L1	2.97e-06	81	103	6	GO:0035869
GeneOntologyCellularComponent	photoreceptor cell cilium	WHRN CEP290 PCDHB13 PCDHB8 SPTBN5 RP1L1	6.53e-05	139	103	6	GO:0097733
GeneOntologyCellularComponent	9+0 non-motile cilium	WHRN CEP290 PCDHB13 PCDHB8 SPTBN5 RP1L1	1.11e-04	153	103	6	GO:0097731
GeneOntologyCellularComponent	perinuclear region of cytoplasm	WHRN ERBB2 SYNE1 CYFIP2 RAD50 GDPD5 RHPN2 OSBPL6 PLEC ALOX12B MYO16 HCRT PKN3 SORL1	1.95e-04	934	103	14	GO:0048471
GeneOntologyCellularComponent	photoreceptor outer segment	CEP290 PCDHB13 PCDHB8 SPTBN5 RP1L1	2.23e-04	111	103	5	GO:0001750
GeneOntologyCellularComponent	FHF complex	HOOK3 HOOK2	2.38e-04	5	103	2	GO:0070695
GeneOntologyCellularComponent	photoreceptor disc membrane	PCDHB13 PCDHB8 SPTBN5	2.78e-04	26	103	3	GO:0097381
GeneOntologyCellularComponent	manchette	RIMBP3 RIMBP3C RIMBP3B	3.48e-04	28	103	3	GO:0002177
GeneOntologyCellularComponent	non-motile cilium	WHRN CEP290 PCDHB13 PCDHB8 SPTBN5 RP1L1	4.23e-04	196	103	6	GO:0097730
GeneOntologyCellularComponent	actin cytoskeleton	WHRN SIPA1L3 CDC42BPB MPRIP SPTBN5 TFPT MACF1 MYO16 FCHSD1 CCDC102A	5.54e-04	576	103	10	GO:0015629
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	6.60e-04	8	103	2	GO:0106139
GeneOntologyCellularComponent	cis-Golgi network	HOOK3 GOLIM4 LRPAP1 PCNT	8.29e-04	85	103	4	GO:0005801
GeneOntologyCellularComponent	other organism part	C4A C4B	8.46e-04	9	103	2	GO:0044217
GeneOntologyCellularComponent	bBAF complex	SMARCA2 SMARCA4	1.05e-03	10	103	2	GO:0140092
GeneOntologyCellularComponent	microtubule associated complex	DNHD1 HAUS5 SPTBN5 CCDC65 KIFC1	1.21e-03	161	103	5	GO:0005875
GeneOntologyCellularComponent	centriole	PLA2G3 CEP290 SFI1 CEP295 PCNT	1.63e-03	172	103	5	GO:0005814
GeneOntologyCellularComponent	endoplasmic reticulum-plasma membrane contact site	SACM1L C2CD2L	1.81e-03	13	103	2	GO:0140268
GeneOntologyCellularComponent	microtubule organizing center	WHRN PLA2G3 CEP290 HAUS5 SFI1 HOOK3 CEP295 HOOK2 CCDC65 UVRAG KIFC1 PCNT	1.88e-03	919	103	12	GO:0005815
GeneOntologyCellularComponent	npBAF complex	SMARCA2 SMARCA4	2.11e-03	14	103	2	GO:0071564
GeneOntologyCellularComponent	GBAF complex	SMARCA2 SMARCA4	2.11e-03	14	103	2	GO:0140288
GeneOntologyCellularComponent	mitotic spindle microtubule	HAUS5 CEP295	2.11e-03	14	103	2	GO:1990498
GeneOntologyCellularComponent	HOPS complex	HOOK3 HOOK2	2.11e-03	14	103	2	GO:0030897
GeneOntologyCellularComponent	nBAF complex	SMARCA2 SMARCA4	2.76e-03	16	103	2	GO:0071565
Domain	Actinin_actin-bd_CS	SYNE1 SPTBN5 MACF1 PLEC UTRN	1.18e-07	23	99	5	IPR001589
Domain	ACTININ_2	SYNE1 SPTBN5 MACF1 PLEC UTRN	1.18e-07	23	99	5	PS00020
Domain	ACTININ_1	SYNE1 SPTBN5 MACF1 PLEC UTRN	1.18e-07	23	99	5	PS00019
Domain	Spectrin_repeat	SYNE1 SPTBN5 MACF1 PLEC UTRN	4.06e-07	29	99	5	IPR002017
Domain	Spectrin/alpha-actinin	SYNE1 SPTBN5 MACF1 PLEC UTRN	6.79e-07	32	99	5	IPR018159
Domain	SPEC	SYNE1 SPTBN5 MACF1 PLEC UTRN	6.79e-07	32	99	5	SM00150
Domain	Spectrin	SYNE1 SPTBN5 MACF1 UTRN	6.09e-06	23	99	4	PF00435
Domain	CH	SYNE1 SPTBN5 MACF1 PLEC UTRN	2.43e-05	65	99	5	SM00033
Domain	SnAC	SMARCA2 SMARCA4	2.78e-05	2	99	2	SM01314
Domain	Gln-Leu-Gln_QLQ	SMARCA2 SMARCA4	2.78e-05	2	99	2	IPR014978
Domain	SnAC	SMARCA2 SMARCA4	2.78e-05	2	99	2	IPR029295
Domain	SnAC	SMARCA2 SMARCA4	2.78e-05	2	99	2	PF14619
Domain	QLQ	SMARCA2 SMARCA4	2.78e-05	2	99	2	SM00951
Domain	QLQ	SMARCA2 SMARCA4	2.78e-05	2	99	2	PS51666
Domain	QLQ	SMARCA2 SMARCA4	2.78e-05	2	99	2	PF08880
Domain	CH	SYNE1 SPTBN5 MACF1 PLEC UTRN	3.48e-05	70	99	5	PF00307
Domain	-	SYNE1 SPTBN5 MACF1 PLEC UTRN	3.73e-05	71	99	5	1.10.418.10
Domain	CH	SYNE1 SPTBN5 MACF1 PLEC UTRN	4.27e-05	73	99	5	PS50021
Domain	BROMODOMAIN_1	ASH1L BRPF1 SMARCA2 SMARCA4	4.29e-05	37	99	4	PS00633
Domain	Bromodomain	ASH1L BRPF1 SMARCA2 SMARCA4	4.77e-05	38	99	4	PF00439
Domain	CH-domain	SYNE1 SPTBN5 MACF1 PLEC UTRN	4.86e-05	75	99	5	IPR001715
Domain	BROMODOMAIN_2	ASH1L BRPF1 SMARCA2 SMARCA4	6.47e-05	41	99	4	PS50014
Domain	BROMO	ASH1L BRPF1 SMARCA2 SMARCA4	7.12e-05	42	99	4	SM00297
Domain	Bromodomain	ASH1L BRPF1 SMARCA2 SMARCA4	7.12e-05	42	99	4	IPR001487
Domain	-	ASH1L BRPF1 SMARCA2 SMARCA4	7.12e-05	42	99	4	1.20.920.10
Domain	SPAR_C	SIPA1L3 SIPA1L2	8.32e-05	3	99	2	PF11881
Domain	SIPA1L_C	SIPA1L3 SIPA1L2	8.32e-05	3	99	2	IPR021818
Domain	SH3_2	DOCK3 RIMBP3 RIMBP3C RIMBP3B FCHSD1	9.37e-05	86	99	5	IPR011511
Domain	SH3_2	DOCK3 RIMBP3 RIMBP3C RIMBP3B FCHSD1	9.37e-05	86	99	5	PF07653
Domain	HSA	SMARCA2 SMARCA4	1.66e-04	4	99	2	SM00573
Domain	HSA	SMARCA2 SMARCA4	1.66e-04	4	99	2	PS51204
Domain	HSA_dom	SMARCA2 SMARCA4	1.66e-04	4	99	2	IPR014012
Domain	HSA	SMARCA2 SMARCA4	1.66e-04	4	99	2	PF07529
Domain	Anaphylatoxin_comp_syst	C4A C4B	2.75e-04	5	99	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	2.75e-04	5	99	2	IPR001840
Domain	Bromodomain_CS	BRPF1 SMARCA2 SMARCA4	3.44e-04	26	99	3	IPR018359
Domain	BRK	SMARCA2 SMARCA4	4.11e-04	6	99	2	SM00592
Domain	-	MACF1 PLEC	4.11e-04	6	99	2	3.90.1290.10
Domain	HOOK	HOOK3 HOOK2	4.11e-04	6	99	2	PF05622
Domain	Hook-related_fam	HOOK3 HOOK2	4.11e-04	6	99	2	IPR008636
Domain	BRK_domain	SMARCA2 SMARCA4	4.11e-04	6	99	2	IPR006576
Domain	BRK	SMARCA2 SMARCA4	4.11e-04	6	99	2	PF07533
Domain	ANATO	C4A C4B	5.74e-04	7	99	2	SM00104
Domain	Plectin_repeat	MACF1 PLEC	5.74e-04	7	99	2	IPR001101
Domain	ANATO	C4A C4B	5.74e-04	7	99	2	PF01821
Domain	Hr1	RHPN2 PKN3	5.74e-04	7	99	2	SM00742
Domain	Plectin	MACF1 PLEC	5.74e-04	7	99	2	PF00681
Domain	ANAPHYLATOXIN_2	C4A C4B	5.74e-04	7	99	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	5.74e-04	7	99	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	5.74e-04	7	99	2	IPR000020
Domain	PLEC	MACF1 PLEC	5.74e-04	7	99	2	SM00250
Domain	FN3	LRFN1 LRFN3 RIMBP3 RIMBP3C RIMBP3B SORL1	6.68e-04	199	99	6	PS50853
Domain	Thiol-ester_cl	C4A C4B	7.63e-04	8	99	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	7.63e-04	8	99	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	7.63e-04	8	99	2	IPR019742
Domain	HR1	RHPN2 PKN3	7.63e-04	8	99	2	PF02185
Domain	SH3_9	RIMBP3 RIMBP3C RIMBP3B FCHSD1	7.85e-04	78	99	4	PF14604
Domain	FN3_dom	LRFN1 LRFN3 RIMBP3 RIMBP3C RIMBP3B SORL1	8.63e-04	209	99	6	IPR003961
Domain	SH3	DOCK3 RIMBP3 MACF1 RIMBP3C RIMBP3B FCHSD1	1.02e-03	216	99	6	PS50002
Domain	SH3_domain	DOCK3 RIMBP3 MACF1 RIMBP3C RIMBP3B FCHSD1	1.12e-03	220	99	6	IPR001452
Domain	A2M_N	C4A C4B	1.22e-03	10	99	2	PF01835
Domain	A2M_N	C4A C4B	1.22e-03	10	99	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	1.22e-03	10	99	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	1.22e-03	10	99	2	PS00477
Domain	A2M	C4A C4B	1.22e-03	10	99	2	PF00207
Domain	A2M_N_2	C4A C4B	1.22e-03	10	99	2	IPR011625
Domain	A2M_comp	C4A C4B	1.22e-03	10	99	2	IPR011626
Domain	A2M_N_2	C4A C4B	1.22e-03	10	99	2	PF07703
Domain	Rap_GAP	SIPA1L3 SIPA1L2	1.22e-03	10	99	2	PF02145
Domain	A2M_recep	C4A C4B	1.22e-03	10	99	2	PF07677
Domain	A2M_comp	C4A C4B	1.22e-03	10	99	2	PF07678
Domain	Macroglobln_a2	C4A C4B	1.22e-03	10	99	2	IPR001599
Domain	Rap_GAP_dom	SIPA1L3 SIPA1L2	1.48e-03	11	99	2	IPR000331
Domain	RAPGAP	SIPA1L3 SIPA1L2	1.48e-03	11	99	2	PS50085
Domain	L_dom-like	ERBB2 LRFN1 LRFN3 IGFALS PRELP LRRC28 LRRC74B	1.81e-03	328	99	7	IPR032675
Domain	SSD	ZDHHC22 DISP3	2.09e-03	13	99	2	IPR000731
Domain	SSD	ZDHHC22 DISP3	2.09e-03	13	99	2	PS50156
Domain	LRR_8	LRFN1 LRFN3 IGFALS PRELP LRRC28	2.17e-03	171	99	5	PF13855
Domain	Leu-rich_rpt_typical-subtyp	LRFN1 LRFN3 IGFALS PRELP LRRC28	2.52e-03	177	99	5	IPR003591
Domain	LRR_TYP	LRFN1 LRFN3 IGFALS PRELP LRRC28	2.52e-03	177	99	5	SM00369
Domain	FN3	LRFN1 LRFN3 RIMBP3C RIMBP3B SORL1	3.05e-03	185	99	5	SM00060
Domain	Leu-rich_rpt	LRFN1 LRFN3 IGFALS PRELP LRRC28 LRRC74B	3.21e-03	271	99	6	IPR001611
Domain	C345C	C4A C4B	3.59e-03	17	99	2	SM00643
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	4.03e-03	18	99	2	IPR008930
Domain	NTR	C4A C4B	4.48e-03	19	99	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	4.48e-03	19	99	2	IPR018933
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 LRFN1 SYNE1 SIPA1L3 ARMCX4 CCDC177 CDC42BPB CYFIP2 MPRIP RAD50 SART1 HOOK3 CELSR2 EHMT1 SMARCA4 MACF1 NIPBL PCNT	1.05e-09	963	108	18	28671696
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DOCK3 ERBB2 LRFN1 RNPEPL1 TSNARE1 SIPA1L3 SFI1 CDC42BPB MPRIP C2CD2L GDPD5 CELSR2 PROM2 EHMT1 PLEC SIPA1L2 UVRAG PKN3 PCNT	1.35e-09	1105	108	19	35748872
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SYNE1 SIPA1L3 APAF1 CDC42BPB ARHGEF15 C2CD2L EHMT1 MACF1 PCNT	3.80e-08	225	108	9	12168954
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERBB2 HAUS5 ASH1L EMILIN3 C2CD2L RAD50 SART1 TFPT BRPF1 SUPT7L SMARCA2 EHMT1 SMARCA4 MACF1 CEP295 SIPA1L2 SORL1	6.35e-08	1116	108	17	31753913
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NCOA2 DOCK3 FAM86B1 SYNE1 SIPA1L3 PLA2G3 CEP290 ASH1L ARMCX4 CDC42BPB MPRIP SMARCA4 MACF1 LRPAP1 PLEC UTRN NIPBL PCNT	8.75e-08	1285	108	18	35914814
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	1.16e-07	4	108	3	19091768
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SYNE1 SIPA1L3 ZNF767P CDC42BPB CYFIP2 MPRIP C2CD2L MEST TFPT GTF2H4 SUPT7L SMARCA2 EHMT1 CSTF1 GOLIM4 MACF1 UTRN NIPBL KIFC1	1.69e-07	1497	108	19	31527615
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	2.90e-07	5	108	3	17855024
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 SYNE1 MPRIP RAD50 BRPF1 SMARCA4 MACF1 PLEC	7.35e-07	234	108	8	36243803
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOA2 ERBB2 TSNARE1 SIPA1L3 ASH1L CCDC85C RBBP8NL ZNF767P CDC42BPB PLEKHG4B PROM2 TBC1D22A SMARCA2 EHMT1 MACF1 HOOK2 UTRN PCNT	7.54e-07	1489	108	18	28611215
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SYNE1 XPO4 SACM1L BRINP2 TSPYL5 CEP295	8.24e-07	102	108	6	11214970
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 SIPA1L3 CEP290 ZNF623 CDC42BPB ARHGEF15 DISP3 MACF1 TSPYL5 POM121B	3.35e-06	493	108	10	15368895
Pubmed	ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF.	MEST SMARCA2 SMARCA4	3.44e-06	10	108	3	23129809
Pubmed	Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.	RAD50 SMARCA2 SMARCA4	6.28e-06	12	108	3	15140983
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	9.55e-06	2	108	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	9.55e-06	2	108	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	9.55e-06	2	108	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	9.55e-06	2	108	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	9.55e-06	2	108	2	19062096
Pubmed	The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.	SMARCA2 SMARCA4	9.55e-06	2	108	2	8670841
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	9.55e-06	2	108	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	9.55e-06	2	108	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	9.55e-06	2	108	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	9.55e-06	2	108	2	19933335
Pubmed	Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.	SMARCA2 SMARCA4	9.55e-06	2	108	2	23163725
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	9.55e-06	2	108	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	9.55e-06	2	108	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	9.55e-06	2	108	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	9.55e-06	2	108	2	12207352
Pubmed	LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro.	LRPAP1 SORL1	9.55e-06	2	108	2	11557679
Pubmed	Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.	SMARCA2 SMARCA4	9.55e-06	2	108	2	23076393
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	9.55e-06	2	108	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	9.55e-06	2	108	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	9.55e-06	2	108	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	9.55e-06	2	108	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	9.55e-06	2	108	2	34299197
Pubmed	Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.	SMARCA2 SMARCA4	9.55e-06	2	108	2	9603422
Pubmed	The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.	SMARCA2 SMARCA4	9.55e-06	2	108	2	15576411
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	9.55e-06	2	108	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	9.55e-06	2	108	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	9.55e-06	2	108	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	9.55e-06	2	108	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	9.55e-06	2	108	2	23918728
Pubmed	SWI/SNF gene variants and glioma risk and outcome.	SMARCA2 SMARCA4	9.55e-06	2	108	2	23276717
Pubmed	Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.	SMARCA2 SMARCA4	9.55e-06	2	108	2	27097303
Pubmed	Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.	SMARCA2 SMARCA4	9.55e-06	2	108	2	15240517
Pubmed	Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.	SMARCA2 SMARCA4	9.55e-06	2	108	2	26564006
Pubmed	SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.	SMARCA2 SMARCA4	9.55e-06	2	108	2	33027072
Pubmed	SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.	SMARCA2 SMARCA4	9.55e-06	2	108	2	28038711
Pubmed	Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein.	LRPAP1 SORL1	9.55e-06	2	108	2	8940146
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	9.55e-06	2	108	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	9.55e-06	2	108	2	3037333
Pubmed	A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.	SMARCA2 SMARCA4	9.55e-06	2	108	2	23872584
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	9.55e-06	2	108	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	9.55e-06	2	108	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	9.55e-06	2	108	2	1699796
Pubmed	Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.	SMARCA2 SMARCA4	9.55e-06	2	108	2	23963727
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	9.55e-06	2	108	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	9.55e-06	2	108	2	2997024
Pubmed	SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.	SMARCA2 SMARCA4	9.55e-06	2	108	2	12493776
Pubmed	Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.	SMARCA2 SMARCA4	9.55e-06	2	108	2	31375262
Pubmed	Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.	SMARCA2 SMARCA4	9.55e-06	2	108	2	23088494
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	9.55e-06	2	108	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	9.55e-06	2	108	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	9.55e-06	2	108	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	9.55e-06	2	108	2	21857912
Pubmed	Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.	SMARCA2 SMARCA4	9.55e-06	2	108	2	17075831
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	9.55e-06	2	108	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	9.55e-06	2	108	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	9.55e-06	2	108	2	4514997
Pubmed	SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.	SMARCA2 SMARCA4	9.55e-06	2	108	2	20333683
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	9.55e-06	2	108	2	21345967
Pubmed	SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.	SMARCA2 SMARCA4	9.55e-06	2	108	2	34812766
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	9.55e-06	2	108	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	9.55e-06	2	108	2	3167981
Pubmed	Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.	SMARCA2 SMARCA4	9.55e-06	2	108	2	32855269
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	9.55e-06	2	108	2	7545960
Pubmed	Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.	SMARCA2 SMARCA4	9.55e-06	2	108	2	30478150
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	9.55e-06	2	108	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	9.55e-06	2	108	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	9.55e-06	2	108	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	9.55e-06	2	108	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	9.55e-06	2	108	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	9.55e-06	2	108	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	9.55e-06	2	108	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	9.55e-06	2	108	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	9.55e-06	2	108	2	29080553
Pubmed	Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.	SMARCA2 SMARCA4	9.55e-06	2	108	2	22721696
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	9.55e-06	2	108	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	9.55e-06	2	108	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	9.55e-06	2	108	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	9.55e-06	2	108	2	17728371
Pubmed	Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.	SMARCA2 SMARCA4	9.55e-06	2	108	2	18508913
Pubmed	Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.	SMARCA2 SMARCA4	9.55e-06	2	108	2	11719516
Pubmed	Structure and organization of the C4 genes.	C4A C4B	9.55e-06	2	108	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	9.55e-06	2	108	2	6149581
Pubmed	Coding variants in the PCNT and CEP295 genes contribute to breast cancer risk in Chinese women.	CEP295 PCNT	9.55e-06	2	108	2	34418690
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	9.55e-06	2	108	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	9.55e-06	2	108	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	9.55e-06	2	108	2	2387317
Interaction	CEP63 interactions	SYNE1 HAUS5 CCDC85C MBIP HOOK3 BRPF1 MACF1 PCNT	4.13e-06	179	104	8	int:CEP63
Interaction	HOOK1 interactions	SIPA1L3 HAUS5 RAD50 RIMBP3 HOOK3 BRPF1 HOOK2 PLEC SIPA1L2	4.27e-06	240	104	9	int:HOOK1
Interaction	FAM167A interactions	HAUS5 CDC42BPB CYFIP2 HOOK2 UTRN CCDC102A	1.04e-05	96	104	6	int:FAM167A
Interaction	WHAMMP3 interactions	SYNE1 HAUS5 MPRIP HOOK3 HOOK2 PCNT	3.54e-05	119	104	6	int:WHAMMP3
Interaction	PCNT interactions	DCPS SYNE1 CEP290 MACF1 PLEC UTRN NIPBL PCNT	3.57e-05	241	104	8	int:PCNT
Cytoband	6p21.3	RING1 GTF2H4 C4A C4B ABHD16A KIFC1	2.95e-05	250	108	6	6p21.3
Cytoband	22q11.21	RIMBP3 RIMBP3C RIMBP3B LRRC74B	1.43e-04	111	108	4	22q11.21
Cytoband	Ensembl 112 genes in cytogenetic band chr6p21	BNIP5 RING1 GTF2H4 C4A C4B ABHD16A KIFC1	1.96e-04	503	108	7	chr6p21
GeneFamily	EF-hand domain containing\|Plakins	MACF1 PLEC	3.30e-04	8	63	2	939
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	4.23e-04	9	63	2	1234
GeneFamily	PDZ domain containing	WHRN SIPA1L3 RHPN2 SIPA1L2	1.95e-03	152	63	4	1220
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	ERBB2 SYNE1 SMARCA2 GOLIM4 MACF1 UTRN PKN3 FAM167B	2.55e-08	198	106	8	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ASH1L ARHGEF15 MACF1 UTRN NIPBL PCNT FAM167B	5.19e-07	200	106	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRFN3 ARMCX4 SMARCA2 GOLIM4 UTRN PKN3	4.77e-06	181	106	6	4ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPRIP HOOK3 SMARCA2 SMARCA4 MACF1 UTRN	6.30e-06	190	106	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ERBB2 SYNE1 CYFIP2 MACF1 UTRN SORL1	8.20e-06	199	106	6	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	ERBB2 SYNE1 CYFIP2 MACF1 UTRN SORL1	8.20e-06	199	106	6	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	ERBB2 SYNE1 CYFIP2 RAD50 MACF1 UTRN	8.44e-06	200	106	6	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	XPO4 ZNF623 SART1 TBC1D22A LRPAP1	3.27e-05	153	106	5	553dff9688a1996d8f4ba16e60c683593d781389
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	XPO4 ZNF623 SART1 TBC1D22A LRPAP1	3.27e-05	153	106	5	88ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	SYNE1 ASH1L SFI1 GDPD5 MACF1	3.59e-05	156	106	5	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB2 PRELP BRINP2 HOOK2 SORL1	4.17e-05	161	106	5	9f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	ASH1L SFI1 SMARCA2 MACF1 UTRN	4.30e-05	162	106	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD5 PRELP C4A FCHSD1 CCDC102A	4.83e-05	166	106	5	aa2df07eff323ded751ced8938af08223d7f2029
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GDPD5 PRELP C4A FCHSD1 CCDC102A	4.83e-05	166	106	5	695298a94d62b8adab083900003ec636fbaae5d9
ToppCell	Cerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SIPA1L3 ZNF786 GDPD5 DISP3 MYO16	4.97e-05	167	106	5	9efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCell	Cerebellum-Neuronal-Inhibitory\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SIPA1L3 ZNF786 GDPD5 DISP3 MYO16	4.97e-05	167	106	5	904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	TBC1D22A BRPF1 OSBPL6 UTRN FCHSD1	6.37e-05	176	106	5	2049767fd591045cfcf5b1071d80798e52843f27
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2G3 PCDHB13 PROM2 MYO16 SORL1	6.55e-05	177	106	5	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	WHRN TSNARE1 EMILIN3 SFI1 PRELP	6.72e-05	178	106	5	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	SYNE1 CYFIP2 MACF1 SIPA1L2 UTRN	7.66e-05	183	106	5	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	NCOA2 SYNE1 CYFIP2 ADAMTS15 UTRN	8.92e-05	189	106	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	Control-Lymphoid_T/NK-NK_CD56bright\|Control / Disease group, lineage and cell class	WHRN SYNE1 GOLIM4 MACF1 UTRN	9.37e-05	191	106	5	e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN MPRIP GTF2H4 SMARCA4 NIPBL	9.84e-05	193	106	5	a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCell	droplet-Heart-HEART-1m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIPA1L3 FCHSD1 KIFC1 PCNT	9.97e-05	101	106	4	6c4524be89cf3eb06769c2963dcded3da1e71ca0
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L MEST MACF1 UTRN NIPBL	1.01e-04	194	106	5	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	facs-Thymus-nan-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WHRN MPRIP GTF2H4 SMARCA4 NIPBL	1.03e-04	195	106	5	79114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCell	COVID-19_Severe-Lymphoid_T/NK-gd_T\|COVID-19_Severe / Disease group, lineage and cell class	SYNE1 CYFIP2 MACF1 CCDC65 UTRN	1.03e-04	195	106	5	9990440bda7fac5d00ef80444fab07459be625e1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 CYFIP2 MACF1 CCDC65 UTRN	1.06e-04	196	106	5	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 CYFIP2 MACF1 CCDC65 UTRN	1.06e-04	196	106	5	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	SYNE1 MBIP ADAMTS15 UTRN MYO16	1.08e-04	197	106	5	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 CEP290 PLEKHG4B OSBPL6 LRRC74B	1.08e-04	197	106	5	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ARHGEF15 GDPD5 PKN3 KIFC1 FAM167B	1.08e-04	197	106	5	491e12a5fca06b86443c0173f5fa750ea3b8a715
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ERBB2 SYNE1 MACF1 UTRN SORL1	1.11e-04	198	106	5	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CEP290 RAD50 SMARCA2 UTRN NIPBL	1.11e-04	198	106	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ERBB2 SYNE1 MACF1 UTRN SORL1	1.11e-04	198	106	5	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EMILIN3 PRELP C4A C4B MYO16	1.11e-04	198	106	5	7a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ASH1L SFI1 MACF1 UTRN	1.14e-04	199	106	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	CEP290 RAD50 SMARCA2 GOLIM4 NIPBL	1.14e-04	199	106	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	CEP290 RAD50 RHPN2 NIPBL SORL1	1.14e-04	199	106	5	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	CEP290 RAD50 SMARCA2 UTRN NIPBL	1.14e-04	199	106	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	ERBB2 CEP290 MBIP ALAS1 UTRN	1.16e-04	200	106	5	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Control_saline-Endothelial-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGEF15 SMARCA2 PLEC SIPA1L2 FAM167B	1.16e-04	200	106	5	e77eba6172cabf85b8028638ed35299f2f079cd8
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGEF15 MACF1 SIPA1L2 UTRN FAM167B	1.16e-04	200	106	5	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	Control_saline-Endothelial\|Control_saline / Treatment groups by lineage, cell group, cell type	ARHGEF15 SMARCA2 PLEC SIPA1L2 FAM167B	1.16e-04	200	106	5	3372c488a39fe812fa94e4f0564594186fea3db5
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	SYNE1 CYFIP2 MACF1 CCDC65 UTRN	1.16e-04	200	106	5	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	NCOA2 RNPEPL1 LRFN3 CEP290 SFI1 C2CD2L GDPD5 SUPT7L UTRN	3.62e-07	199	105	9	1484_DN
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 HOOK3 HOOK2	8.13e-06	12	100	3	DOID:11726 (implicated_via_orthology)
Disease	serum gamma-glutamyl transferase measurement	SIPA1L3 ASH1L CDC42BPB ARHGEF15 CYFIP2 MPRIP CELSR2 RHPN2 EXOC3L4 RP1L1 SIPA1L2 PKN3	6.26e-05	914	100	12	EFO_0004532
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	SMARCA2 SMARCA4	1.13e-04	5	100	2	C3281201
Disease	esterified cholesterol measurement, intermediate density lipoprotein measurement	CELSR2 SMARCA4	3.14e-04	8	100	2	EFO_0008589, EFO_0008595
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA2 SMARCA4	4.03e-04	9	100	2	DOID:0050340 (implicated_via_orthology)
Disease	immature platelet measurement	DOCK3 RNPEPL1 EXOC3L4 PLEC	7.32e-04	119	100	4	EFO_0803541
Disease	Coffin-Siris syndrome	SMARCA2 SMARCA4	8.66e-04	13	100	2	C0265338
Disease	Papillary Renal Cell Carcinoma	DNHD1 ERBB2 APAF1 ALOX12B	9.60e-04	128	100	4	C1306837
Disease	Renal Cell Carcinoma	DNHD1 ERBB2 APAF1 ALOX12B	9.60e-04	128	100	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	DNHD1 ERBB2 APAF1 ALOX12B	9.60e-04	128	100	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	DNHD1 ERBB2 APAF1 ALOX12B	9.60e-04	128	100	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	DNHD1 ERBB2 APAF1 ALOX12B	9.60e-04	128	100	4	C1266044
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	CELSR2 SMARCA4	1.01e-03	14	100	2	EFO_0004611, EFO_0008589
Disease	protein-glutamine gamma-glutamyltransferase e measurement	CYFIP2 RHPN2 EXOC3L4	1.12e-03	60	100	3	EFO_0020690
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	DNHD1 ERBB2 APAF1 ALOX12B	1.64e-03	148	100	4	C0279702
Disease	bipolar disorder, sex interaction measurement	TSNARE1 SIPA1L2	1.68e-03	18	100	2	EFO_0008343, MONDO_0004985
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	CELSR2 SMARCA4	1.68e-03	18	100	2	EFO_0008317, EFO_0008589
Disease	renal cell carcinoma (is_implicated_in)	ERBB2 C4A C4B	1.68e-03	69	100	3	DOID:4450 (is_implicated_in)
Disease	hydrocephalus (implicated_via_orthology)	CCDC85C CELSR2	1.87e-03	19	100	2	DOID:10908 (implicated_via_orthology)
Disease	sodium-coupled monocarboxylate transporter 1 measurement	CELSR2 SMARCA4	1.87e-03	19	100	2	EFO_0802076
Disease	cancer (implicated_via_orthology)	RING1 SMARCA2 SMARCA4 MACF1 NIPBL	2.22e-03	268	100	5	DOID:162 (implicated_via_orthology)
Disease	stroke, coronary artery disease	CELSR2 SMARCA4	2.29e-03	21	100	2	EFO_0000712, EFO_0001645
Disease	cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage	CELSR2 SMARCA4	2.29e-03	21	100	2	EFO_0022246
Disease	blood pressure	SYNE1 MYO16	2.51e-03	22	100	2	EFO_0004325
Disease	Nasopharyngeal carcinoma	ERBB2 SYNE1	2.51e-03	22	100	2	C2931822
Disease	progranulin measurement	NCOA2 CELSR2	2.51e-03	22	100	2	EFO_0004625
Disease	clinical and behavioural ideal cardiovascular health	CELSR2 SMARCA4	2.75e-03	23	100	2	EFO_0007654
Disease	post-traumatic stress disorder symptom measurement	REX1BD SYNE1 TSNARE1	2.76e-03	82	100	3	EFO_0008535
Disease	breast cancer (implicated_via_orthology)	RAD50 SMARCA4	3.24e-03	25	100	2	DOID:1612 (implicated_via_orthology)
Disease	large artery stroke, coronary artery disease	CELSR2 SMARCA4	3.24e-03	25	100	2	EFO_0001645, EFO_0005524

Protein segments in the cluster

Peptide	Gene	Start	Entry
DHIRRLQLINGRTGQ	APAF1	941	O14727
ILALRRLGRQRNQHL	EXOC3L4	666	Q17RC7
RLGRQRNQHLLQHTQ	EXOC3L4	671	Q17RC7
QNLQVIRGRILHNGA	ERBB2	426	P04626
RRHNQRERLNQILLN	ASH1L	2916	Q9NR48
LQQLHLGNRSRQASR	DISP3	156	Q9P2K9
SHALQLNNRQIRGLE	C4B	1341	P0C0L5
LSLQHRRAQLLDING	CCDC65	416	Q8IXS2
RGLVTRTVRQHLNLN	ABHD16A	396	O95870
LEELQLGHNRIRQLA	IGFALS	316	P35858
RRHLRQNQRLLEAVG	ARHGEF15	816	O94989
RSQQLALLLRNATQH	CELSR2	2051	Q9HCU4
LRILRSNQHGIRRNL	CELSR2	2401	Q9HCU4
GAQLAERRLRQRLVQ	DNHD1	4431	Q96M86
INQGLDRLRRVSHQG	LRPAP1	231	P30533
LRNILHQGQEAILQR	DCPS	241	Q96C86
LNSNVQLAGLRLIRH	ARMCX4	2136	Q5H9R4
AAQRNSQGAHLLQRR	ADAMTS15	146	Q8TE58
LLVEQGRLQLQADRH	RAD50	346	Q92878
QLQQLLHRERDGVVR	RIMBP3B	116	A6NNM3
QLQQLLHRERDGVVR	RIMBP3C	116	A6NJZ7
RVVSRGNKLHLQLNQ	PCDHB13	66	Q9Y5F0
QNRLLQDQLRVALGR	MPRIP	696	Q6WCQ1
EGRVLRRQHQRNVKL	ALAS1	496	P13196
FLARQHLLQRISIRQ	MYO16	1161	Q9Y6X6
RHGLETQHRLNQQQL	HOOK2	496	Q96ED9
LGNLRHLILGNNQIR	LRFN1	136	Q9P244
HLILGNNQIRRVESA	LRFN1	141	Q9P244
HLRTLRRQANQANKL	LINC00312	51	Q9Y6C7
VNRRLQQHLLEIRGL	CCDC85C	56	A6NKD9
ERRRLHNQLQELKGN	KIFC1	296	Q9BW19
HSRVLEQLRGNVLLN	FAM86B1	156	Q8N7N1
GNRQHRRAFLISLLN	NIPBL	2401	Q6KC79
LRRGHIQRLNLRYTQ	GDPD5	421	Q8WTR4
HQRQLRRRGALPQES	KCNK13	161	Q9HB14
QLRGLVNLRHLILSN	LRFN3	126	Q9BTN0
HRQLLLRELQAKQQR	HAUS5	371	O94927
GLQSILHKNRLRNQV	CDC42BPB	1211	Q9Y5S2
QRHVQLLGRSIDLNR	CYFIP2	776	Q96F07
GRRHLQLQTQLEQLQ	HOOK3	241	Q86VS8
LNQNAELRSRLNRIH	OSBPL6	431	Q9BZF3
RRHSQALEALQQRLQ	PCNT	1811	O95613
LTRAGLRRLQRQQQV	GPR45	241	Q9Y5Y3
LNQHTQLEGRLQDLR	MACF1	3486	Q9UPN3
KTLGARQRLQARRQH	POM121B	816	A6NF01
QEALHQQRLQGHLLR	GOLIM4	431	O00461
GHRVLQRLEQRRQQA	FCHSD1	346	Q86WN1
HLLLAQQQLRARARA	RBBP8NL	356	Q8NC74
GRAQHQINGRVRQLL	CCDC105	141	Q8IYK2
QINGRVRQLLRQREV	CCDC105	146	Q8IYK2
LQEVDGQLGQQIRRH	BNIP5	546	P0C671
RRQLLSGHLTQDQVR	DOCK3	126	Q8IZD9
NRLFLRQLRASHLGN	C2CD2L	286	O14523
GRNRAKHLRQTIQSL	CEP290	1256	O15078
QLEHLQSRLRRQQQN	CCDC102A	501	Q96A19
RQRLNQISHDIRQRN	ALOX12B	666	O75342
RLQNIEAHLRLQTGG	MBIP	251	Q9NS73
RHEALLQGRTRQQRQ	CCDC177	511	Q9NQR7
GSRLQAGHRQVLNLR	EMILIN3	641	Q9NT22
AERRNLLSLGHNNIV	CSTF1	386	Q05048
TQALRHQRGLRLYNQ	CEP295	2546	Q9C0D2
RSLQAQLQRLGVLHV	SACM1L	406	Q9NTJ5
RNRVVQNGLRARLQL	EHMT1	1116	Q9H9B1
LRHLGLQNRRINLLS	MEST	131	Q5EB52
QAQDRQLAGQLLRLR	FAM167B	91	Q9BTA0
QLAGQLLRLRAQLHR	FAM167B	96	Q9BTA0
QDRVLIRLSRLHNQQ	RING1	121	Q06587
SHALQLNNRQIRGLE	C4A	1341	P0C0L4
RLQNQRGGRIRLQDI	FTMT	131	Q8N4E7
LRQGSAQELNLRHRG	LRRC74B	76	Q6ZQY2
GHVQQLLRSSNRRLE	PKN3	51	Q6P5Z2
RVVSRGNKLHLQLNQ	PCDHB8	66	Q9UN66
LQGRLQRLLQASGNH	HCRT	76	O43612
LQQIRRNLAHQQHGV	SFI1	401	A8K8P3
ESQHNRQLLRGALRR	SFI1	676	A8K8P3
QLESQLHRLRQLLEQ	UTRN	3341	P46939
RNIAARNIVNRNGHQ	UVRAG	46	Q9P2Y5
QTQGRLHPNLRRAIQ	RNPEPL1	656	Q9HAU8
HLAQRLSQLLNLQLR	SORL1	476	Q92673
NILHRLLKNGNVRNT	BPY2	46	O14599
HRIGQQNEVRVLRLC	SMARCA2	1161	P51531
HQLSLRRQQIGERLN	SYNE1	7766	Q8NF91
RALRHLRLANNQLQF	LRRC28	111	Q86X40
QLQQLLHRERDGVVR	RIMBP3	116	Q9UFD9
HRIGQQNEVRVLRLC	SMARCA4	1191	P51532
NNRQQLLRKRHIGND	SIPA1L2	691	Q9P2F8
PNNRQQLLRKRHIGN	SIPA1L3	706	O60292
RILRNRHDLLNVSQG	ST6GALNAC5	151	Q9BVH7
RNLEQLRLSQNHISR	PRELP	171	P51888
GLRLLSANVRQLHQA	WHRN	31	Q9P202
TIQLIQHNRRLRNLI	SUPT7L	66	O94864
RLQQRRHQLQDKGTD	PLA2G3	456	Q9NZ20
NDQQRRQLGKSHLRR	RHPN2	401	Q8IUC4
QRLLQHLQGQRKQVA	SPTBN5	516	Q9NRC6
LRSSQRLQKRHQQLE	SPTBN5	1451	Q9NRC6
RHRLKLANNEVGRIQ	BRINP2	746	Q9C0B6
LLRRLQTHLQSQRNC	BRPF1	556	P55201
AQRQREILNQHLRQR	NCOA2	1236	Q15596
SRGLNRVHLQCRNLQ	GTF2H4	6	Q92759
LLQRRLENVENLLHN	ZNF767P	76	Q75MW2
QLLLILRGQTRHQVR	ZDHHC22	206	Q8N966
RLHGQLQRHQQQLLA	XPO4	506	Q9C0E2
ARQLLAGASRHQLQR	TSNARE1	471	Q96NA8
NRLHQVQRITRRLQQ	TFPT	101	P0C1Z6
TGELLLQTQQRRHRL	RP1L1	1596	Q8IWN7
LQTQQRRHRLRGLRN	RP1L1	1601	Q8IWN7
QRLQEEAQGLRNLHQ	PROM2	656	Q8N271
LVQRIHQLQAERAQG	REX1BD	41	Q96EN9
RLVLTSNNRLQQLEH	PLEKHG4B	446	Q96PX9
LAQRHRQQLQLELLE	PYCARD-AS1	46	I3L0S3
HRNLVDNITGQRLLE	PLEC	4436	Q15149
GRRLRQLQQLQQLRD	SART1	506	O43290
VLRNHSQRQGRPTLQ	TBC1D22A	101	Q8WUA7
NFRQRGQLLRHQRLH	ZNF786	461	Q8N393
QLRRRALGEDLLQNH	SPTY2D1OS	41	A0A0U1RRN3
GRNHILNSDLLLLQR	ZNF623	101	O75123
VRGNQQALRAQLHQL	TCIRG1	111	Q13488
GQLRLQHLERRNHLI	TSPYL5	231	Q86VY4