Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDH_1

ARHGEF28 RASGRF2 ARHGEF38 MCF2 ARHGEF18

9.20e-05631355PS00741
DomainRhoGEF

ARHGEF28 RASGRF2 ARHGEF38 MCF2 ARHGEF18

1.33e-04681355SM00325
DomainRhoGEF

ARHGEF28 RASGRF2 ARHGEF38 MCF2 ARHGEF18

1.52e-04701355PF00621
DomainDH_2

ARHGEF28 RASGRF2 ARHGEF38 MCF2 ARHGEF18

1.52e-04701355PS50010
DomainZnf_NFX1

ZNFX1 NFX1

1.55e-0431352IPR000967
DomainZnF_NFX

ZNFX1 NFX1

1.55e-0431352SM00438
Domainzf-NF-X1

ZNFX1 NFX1

1.55e-0431352PF01422
Domain-

ARHGEF28 RASGRF2 ARHGEF38 MCF2 ARHGEF18

1.63e-047113551.20.900.10
DomainDH-domain

ARHGEF28 RASGRF2 ARHGEF38 MCF2 ARHGEF18

1.63e-04711355IPR000219
DomainHelicase_C_2

RTEL1 DDX11

3.08e-0441352PF13307
DomainDEAD_2

RTEL1 DDX11

3.08e-0441352PF06733
DomainDEAD_2

RTEL1 DDX11

3.08e-0441352IPR010614
DomainATP-dep_Helicase_C

RTEL1 DDX11

3.08e-0441352IPR006555
DomainHelicase-like_DEXD_c2

RTEL1 DDX11

3.08e-0441352IPR006554
DomaincAMP_dep_PK_reg_su

PRKAR2A PRKAR2B

3.08e-0441352IPR012198
DomainDNA_helicase_DNA-repair_Rad3

RTEL1 DDX11

3.08e-0441352IPR013020
DomainHELICASE_ATP_BIND_2

RTEL1 DDX11

3.08e-0441352PS51193
DomainHelic_SF1/SF2_ATP-bd_DinG/Rad3

RTEL1 DDX11

3.08e-0441352IPR014013
DomainDEXDc2

RTEL1 DDX11

3.08e-0441352SM00488
DomainHELICc2

RTEL1 DDX11

3.08e-0441352SM00491
Domain-

MACF1 PLEC

7.63e-04613523.90.1290.10
DomainRIIa

PRKAR2A PRKAR2B

7.63e-0461352SM00394
DomainIRF-3

IRF8 IRF4

1.06e-0371352PF10401
DomainPlectin

MACF1 PLEC

1.06e-0371352PF00681
DomainRIIa

PRKAR2A PRKAR2B

1.06e-0371352PF02197
DomainIRF-3

IRF8 IRF4

1.06e-0371352SM01243
DomainPlectin_repeat

MACF1 PLEC

1.06e-0371352IPR001101
DomainInterferon_reg_factor-3

IRF8 IRF4

1.06e-0371352IPR019471
DomainPLEC

MACF1 PLEC

1.06e-0371352SM00250
DomainSpectrin_repeat

MCF2 MACF1 PLEC

1.18e-03291353IPR002017
DomainSPEC

MCF2 MACF1 PLEC

1.57e-03321353SM00150
DomainSpectrin/alpha-actinin

MCF2 MACF1 PLEC

1.57e-03321353IPR018159
DomainIRF

IRF8 IRF4

1.81e-0391352SM00348
DomainIRF

IRF8 IRF4

1.81e-0391352PF00605
DomainInterferon_reg_fac_CS

IRF8 IRF4

1.81e-0391352IPR019817
DomainInterferon_reg_fact_DNA-bd_dom

IRF8 IRF4

1.81e-0391352IPR001346
DomainIRF_1

IRF8 IRF4

1.81e-0391352PS00601
DomainIRF_2

IRF8 IRF4

1.81e-0391352PS51507
PathwayBIOCARTA_AKAPCENTROSOME_PATHWAY

PRKAR2A PRKAR2B PRKCE

4.63e-0512863MM1460
PathwayBIOCARTA_AKAPCENTROSOME_PATHWAY

PRKAR2A PRKAR2B PRKCE

7.60e-0514863M15347
Pubmed

Isoform-specific targeting of PKA to multivesicular bodies.

MAP1LC3A PRKAR2A PRKAR2B AKAP11

1.11e-0712137421502359
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

MYO5A RASGRF2 ARHGEF18 PRKAR2A PRKAR2B PLEC HSPA9

2.03e-06147137716959763
Pubmed

RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma.

MYO5A ZNF185 MYO1B PLEC HSPA9

4.76e-0662137535568845
Pubmed

IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia.

IRF8 IRF4

1.54e-052137234331664
Pubmed

A role for interferon regulatory factor 4 in receptor editing.

IRF8 IRF4

1.54e-052137218285461
Pubmed

Shared and distinct functions of the transcription factors IRF4 and IRF8 in myeloid cell development.

IRF8 IRF4

1.54e-052137222003407
Pubmed

Cloning and characterization of a novel A-kinase anchoring protein. AKAP 220, association with testicular peroxisomes.

PRKAR2A AKAP11

1.54e-05213728621616
Pubmed

A novel dual kinase function of the RET proto-oncogene negatively regulates activating transcription factor 4-mediated apoptosis.

RET ATF4

1.54e-052137225795775
Pubmed

IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development.

IRF8 IRF4

1.54e-052137212832394
Pubmed

Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis.

IRF8 IRF4

1.54e-052137220585039
Pubmed

IRF4 and IRF8 Act in CD11c+ Cells To Regulate Terminal Differentiation of Lung Tissue Dendritic Cells.

IRF8 IRF4

1.54e-052137226746189
Pubmed

IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity.

IRF8 IRF4

1.54e-052137215728463
Pubmed

Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development.

IRF8 IRF4

1.54e-052137217971486
Pubmed

IFN regulatory factors 4 and 8 expression in the NOD mouse.

IRF8 IRF4

1.54e-052137221647406
Pubmed

Altered expression of transcription factors IRF4 and IRF8 in peripheral blood B cells is associated with clinical severity and circulating plasma cells frequency in patients with myasthenia gravis.

IRF8 IRF4

1.54e-052137229569949
Pubmed

Interferon consensus sequence binding protein and interferon regulatory factor-4/Pip form a complex that represses the expression of the interferon-stimulated gene-15 in macrophages.

IRF8 IRF4

1.54e-052137210590072
Pubmed

Epistasis between RET and BBS mutations modulates enteric innervation and causes syndromic Hirschsprung disease.

BBS2 RET

1.54e-052137219666486
Pubmed

NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia.

NCOA3 KAT6A

1.54e-052137217805331
Pubmed

The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.

IRF8 IRF4

1.54e-052137223658517
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

TTC24 MYO5A ADAM7 RRP15 MYO1B NKIRAS2 PHF5A GSPT1 DDX11 CDCA2 PMPCA ASPM MACF1 BOD1L1 NGLY1 PLEC KIAA2012 HSPA9

1.54e-0514421371835575683
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

MYO5A ARHGEF18 GRIN2B PRKAR2A PRKAR2B MACF1 PRKCE AKAP11

1.67e-05281137828706196
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOA3 MYO5A ARHGEF18 ZNFX1 GRIN2B JAKMIP2 KIF3A MAGI2 PRKAR2A PRKAR2B MACF1 PRKCE HSPA9 WNK3

2.87e-059631371428671696
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

ANKRD31 RTEL1 ZNFX1 MACF1 PLEC HSPA9

3.24e-05152137634299191
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CASP8AP2 GBF1 THSD7A RTEL1 METTL13 MACF1 AKAP11

3.26e-05225137712168954
Pubmed

Fructooligosaccharides benefits on glucose homeostasis upon high-fat diet feeding require type 2 conventional dendritic cells.

IRF8 IRF4

4.61e-053137238926424
Pubmed

IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development.

IRF8 IRF4

4.61e-053137217114461
Pubmed

Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase.

RET PRKAR2A

4.61e-053137211886862
Pubmed

FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.

CASP8AP2 NCOA3

4.61e-053137215698540
Pubmed

The expansion of the PRAME gene family in Eutheria.

PRAMEF19 PRAMEF18

4.61e-053137221347312
Pubmed

Myocardial Infarction Primes Autoreactive T Cells through Activation of Dendritic Cells.

IRF8 IRF4

4.61e-053137228329691
Pubmed

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2.

IRF8 IRF4

4.61e-053137222037603
Pubmed

ATF4 destabilizes RET through nonclassical GRP78 inhibition to enhance chemosensitivity to bortezomib in human osteosarcoma.

RET ATF4

4.61e-053137231534554
Pubmed

Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.

IRF8 IRF4

4.61e-053137233951726
Pubmed

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming.

IRF8 IRF4

4.61e-053137232375053
Pubmed

Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/- mice.

PRKAR2A PRKAR2B

4.61e-053137226246497
Pubmed

Hematopoietic neoplasms in Prkar2a-deficient mice.

PRKAR2A PRKAR2B

4.61e-053137226608815
Pubmed

Regional variations in the localization of insoluble kinase A regulatory isoforms during rodent brain development.

PRKAR2A PRKAR2B

4.61e-053137215183205
Pubmed

Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.

IRF8 IRF4

4.61e-053137218280186
Pubmed

Localization of a novel human A-kinase-anchoring protein, hAKAP220, during spermatogenesis.

PRKAR2B AKAP11

4.61e-053137210864471
Pubmed

A census of human transcription factors: function, expression and evolution.

FOXS1 NCOA3 NR2C1 ZBED2 IRF8 NKX2-3 E2F7 IRF4 ZNFX1 NFX1 ATF4 GRHL3 POU2F3

6.54e-059081371319274049
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

MYO5A GRIN2B MAGI2 TMEM145 PRKAR2B MACF1 PRKCE PLEC

7.42e-05347137817114649
Pubmed

Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways.

PRKAR2A PRKAR2B PRKCE

7.55e-052113739671211
Pubmed

USP7 controls NGN3 stability and pancreatic endocrine lineage development.

MYO1B GRIN2B MACF1 PLEC

8.29e-0558137437117185
Pubmed

The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.

PRKAR2A PRKAR2B PRKCE

8.72e-052213739151826
Pubmed

Association of protein kinase A with AKAP150 facilitates pepsinogen secretion from gastric chief cells.

PRKAR2A PRKAR2B

9.19e-054137211557526
Pubmed

GSKIP- and GSK3-mediated anchoring strengthens cAMP/PKA/Drp1 axis signaling in the regulation of mitochondrial elongation.

PRKAR2A PRKAR2B

9.19e-054137225920809
Pubmed

The GRHL3-regulated long non-coding RNA lnc-DC modulates keratinocytes differentiation by interacting with IGF2BP2 and up-regulating ZNF750.

ZNF750 GRHL3

9.19e-054137238383230
Pubmed

Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP binding.

PRKAR2A PRKAR2B

9.19e-054137210764601
Pubmed

Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic.

PRKAR2A PRKAR2B

9.19e-054137211102458
Pubmed

Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes.

PRKAR2A AKAP11

9.19e-054137211823486
Pubmed

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively.

IRF8 IRF4

9.19e-054137227637148
Pubmed

D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain.

PRKAR2A PRKAR2B

9.19e-05413729326583
Pubmed

Merocytic Dendritic Cells Compose a Conventional Dendritic Cell Subset with Low Metabolic Activity.

IRF8 IRF4

9.19e-054137232461238
Pubmed

Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8.

IRF8 IRF4

9.19e-054137226437243
Pubmed

IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage.

IRF8 IRF4

9.19e-054137235830859
Pubmed

Localization and quaternary structure of the PKA RIβ holoenzyme.

PRKAR2A PRKAR2B

9.19e-054137222797896
Pubmed

Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors.

IRF8 IRF4

9.19e-054137223975864
Pubmed

Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein.

PRKAR2A PRKAR2B

9.19e-054137220007971
Pubmed

Identification of tethering domains for protein kinase A type Ialpha regulatory subunits on sperm fibrous sheath protein FSC1.

PRKAR2A PRKAR2B

9.19e-05413729852104
Pubmed

Role of Ca2+ transients at the node of the mouse embryo in breaking of left-right symmetry.

KIF3A NODAL

9.19e-054137232743070
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PRAMEF19 ARHGEF18 PRAMEF18 ZNF750 WWC2 NOL4L THOP1 MYPN CPNE3 NFX1 MACF1 BOD1L1 PLEC DEDD

1.02e-0410841371411544199
Pubmed

Developmentally acquired PKA localisation in mouse oocytes and embryos.

PRKAR2A PRKAR2B

1.53e-045137218367160
Pubmed

Association of the type 1 protein phosphatase PP1 with the A-kinase anchoring protein AKAP220.

PRKAR2A AKAP11

1.53e-045137210209101
Pubmed

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis.

IRF8 IRF4

1.53e-045137227067057
Pubmed

Patterns of cyclic AMP-dependent protein kinase gene expression during ontogeny of the murine palate.

PRKAR2A PRKAR2B

1.53e-04513727775586
Pubmed

Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens.

IRF8 IRF4

1.53e-045137210364426
Pubmed

The A-Kinase Anchoring Protein (AKAP) Glycogen Synthase Kinase 3β Interaction Protein (GSKIP) Regulates β-Catenin through Its Interactions with Both Protein Kinase A (PKA) and GSK3β.

PRKAR2A AKAP11

1.53e-045137227484798
Pubmed

Diminished levels of protein kinase A RI alpha and RI beta transcripts and proteins in systemic lupus erythematosus T lymphocytes.

PRKAR2A PRKAR2B

1.53e-045137210228048
Pubmed

Inducible targeting of cDCs and their subsets in vivo.

IRF8 IRF4

1.53e-045137227073171
Pubmed

Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks.

IRF8 IRF4

1.53e-045137224249112
Pubmed

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.

IRF8 IRF4

1.53e-045137226932576
Pubmed

Duplication and positive selection among hominin-specific PRAME genes.

PRAMEF19 PRAMEF18

1.53e-045137216159394
Pubmed

Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.

IRF8 IRF4

1.53e-045137226054719
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

GBF1 MYO5A BMS1 MYO1B ZNFX1 PLEC

1.56e-04202137633005030
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

GBF1 ARHGEF28 CDCA2 WWC2 TIMM50 MACF1 PRKCE AKAP11 BOD1L1 PLEC WNK3 VCPIP1

1.62e-048611371236931259
Pubmed

Role of phosphorylation in the nuclear biology of HIV-1.

PRKAR2A PRKAR2B PRKCE

1.63e-0427137321651489
Pubmed

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.

IRF8 IRF4

2.29e-046137225446897
Pubmed

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation.

IRF8 IRF4

2.29e-046137225288399
Pubmed

Characterization of an A-kinase anchoring protein in human ciliary axonemes.

PRKAR2A PRKAR2B

2.29e-046137212475942
Pubmed

Phosphodiesterase 10A Is Tethered to a Synaptic Signaling Complex in Striatum.

GRIN2B PRKAR2A

2.29e-046137225762721
Pubmed

Ikaros and Aiolos inhibit pre-B-cell proliferation by directly suppressing c-Myc expression.

IRF8 IRF4

2.29e-046137220566697
Pubmed

Computer sequence analysis of human highly conserved zinc finger modules.

ZNF311 ZNF587

2.29e-046137210520746
Pubmed

Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin.

IRF8 IRF4

2.29e-046137224078692
Pubmed

Subcellular dynamics of type II PKA in neurons.

PRKAR2A PRKAR2B

2.29e-046137219447092
Pubmed

Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA.

PRKAR2A PRKAR2B

2.29e-046137211278869
Pubmed

The testis-specific Cα2 subunit of PKA is kinetically indistinguishable from the common Cα1 subunit of PKA.

PRKAR2A PRKAR2B

2.29e-046137221812984
Pubmed

Compensatory dendritic cell development mediated by BATF-IRF interactions.

IRF8 IRF4

2.29e-046137222992524
Pubmed

MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

E2F7 RET TNFRSF21 MTR NODAL

2.40e-04140137520819778
Pubmed

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.

IPPK E2F7 MYO1B NUF2 PHF5A PLEC

2.59e-04222137635941108
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MYO5A RTEL1 MAEA KAT6A ARHGEF38 ARHGEF18 ATP8B1 THOP1 FAM111A GRTP1 GALNT11 ZNF587 MACF1 PRKCE BOD1L1 TAFA5

2.65e-0414891371628611215
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

THNSL1 BMS1 RRP15 GPATCH4 NUF2 PMPCA FBXO28 NFX1 TIMM50 MTR PRKAR2A PRKAR2B AKAP11 MRPL32 HSPA9 VCPIP1

2.79e-0414961371632877691
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYO5A ZNF185 BMS1 RRP15 MYO1B GPATCH4 GSPT1 CDCA2 METTL13 CPNE3 TIMM50 ASPM MACF1 PLEC HSPA9

3.00e-0413531371529467282
Pubmed

Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.

TIMM50 PRKAR2A PRKAR2B AKAP11

3.18e-0482137430274258
Pubmed

A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.

IRF8 IRF4

3.19e-047137222267219
Pubmed

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel.

PRKAR2A PRKAR2B

3.19e-047137211799244
Pubmed

Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain.

PRKAR2A PRKAR2B

3.19e-04713722619996
Pubmed

A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta.

PRKAR2A AKAP11

3.19e-047137212147701
Pubmed

Long-term potentiation in the CA1 hippocampus induced by NR2A subunit-containing NMDA glutamate receptors is mediated by Ras-GRF2/Erk map kinase signaling.

RASGRF2 GRIN2B

3.19e-047137220661302
Pubmed

RNF34 functions in immunity and selective mitophagy by targeting MAVS for autophagic degradation.

TRIM31 MAP1LC3A

3.19e-047137231304625
Pubmed

High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity.

IRF8 IRF4

3.19e-047137232795402
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF2 ARHGEF38 MCF2 ARHGEF18

2.18e-0466814722
GeneFamilyEF-hand domain containing|Plakins

MACF1 PLEC

5.45e-048812939
CoexpressionAtlasB cells, B.Fo.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23+, Spleen, avg-3

MYO5A IRF8 ARHGEF18 IRF4 SAMD9L FAM111A RASGEF1B MACF1 PRKCE KYNU

5.01e-0534512910GSM538201_500
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#4_top-relative-expression-ranked_500

E2F7 NUF2 CDCA2 CCN1

5.23e-05341294gudmap_developingKidney_e15.5_Peripheral blastema_500_k4
CoexpressionAtlasB cells, B.T2.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3

MYO5A IRF8 ARHGEF18 IRF4 SAMD9L FAM111A RASGEF1B MACF1 PRKCE KYNU

5.38e-0534812910GSM538216_500
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THNSL1 GPT NUF2 JAKMIP2 CDCA2 ASPM GPRASP2

7.40e-0716413674307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THNSL1 GPT NUF2 JAKMIP2 CDCA2 ASPM GPRASP2

7.40e-0716413671d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXS1 BCHE MYO1B NUF2 CDCA2 ASPM PRKAR2B

1.14e-0617513673e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TFPI2 E2F7 MCF2 NUF2 DDX11 FAM111A ASPM

2.05e-06191136750854384fdaa0efa2e3227659d544ed09ac102f2
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

E2F7 NUF2 METTL13 ZNF334 ZNF587 ASPM MTR

2.51e-061971367038fd92750257d43d5e980fd06d77742b543f11a
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MCF2 NOL4L GALNT9 RASGEF1B KIAA2012 KYNU

5.85e-061461366b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NDNF THSD7A ZBED2 WWC2 PTCHD1 CCN1

1.35e-051691366815474855a70498a74e52f6583113c63b7267a0c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF THSD7A ZNF185 MYO1B MAGI2 PRKAR2B

1.39e-05170136660bbd738c12e64e483485586c30057304884f5a6
ToppCellCOVID-19-kidney-Podocyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NDNF THSD7A ZNF185 GRIN2B PTH1R MAGI2

1.64e-051751366a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF THSD7A MYO1B JAKMIP2 MAGI2 PRKAR2B

1.75e-0517713664d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF THSD7A MYO1B JAKMIP2 MAGI2 PRKAR2B

1.81e-051781366edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

E2F7 NUF2 POLA2 DDX11 CDCA2 ASPM

1.87e-051791366ac987c9425a1b4106d1b8779a2c5461383eae2ae
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPT POLA2 ZNF334 ASPM POU2F3 WNK3

2.05e-051821366d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPT POLA2 ZNF334 ASPM POU2F3 WNK3

2.05e-05182136692f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPT POLA2 ZNF334 ASPM POU2F3 WNK3

2.05e-05182136602baca9a72c7b559c3e452693b3b134af804c868
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAP1LC3A EXOC8 THOP1 CCN1 SPAG16 VCPIP1

2.18e-0518413662c2125b8030af83f7a6d59a7102d4de8e0ac1988
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

ATP8B1 RET GSPT1 ZNF587 TMEM145 HSPA9

2.39e-051871366a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

NCOA3 IRF8 ARHGEF18 PRKCE NGLY1 KYNU

2.39e-051871366af1327559f7e01bec070881cae52834917c3da65
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 ARHGEF38 NUF2 ITPRID1 CDCA2 FAM111A

2.54e-051891366c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A MYO5A MYO1B ATP8B1 GRIN2B SPAG16

2.61e-05190136611d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FOXS1 MYO1B NUF2 TNFRSF21 CDCA2 PRKAR2B

2.69e-051911366ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

IRF8 E2F7 NUF2 POLA2 CDCA2 ASPM

2.69e-051911366ff2cc4c10aa584b3daeaaf23cd8ee09bdbdf684d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXS1 MYO1B PTH1R SLC16A12 NODAL POU2F3

2.69e-051911366cb75e6c36dbe2e091e407d691c063ec7c4fd5f90
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXS1 MYO1B PTH1R SLC16A12 NODAL POU2F3

2.69e-051911366b2cffea7860dd590b505ee0ebd51aa1978cb5e64
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXS1 MYO1B PTH1R SLC16A12 NODAL POU2F3

2.77e-051921366e5117cdb8af220f60bd1410262078c0306667b4a
ToppCellNS-critical-d_0-4-Lymphoid-NK|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO1B GPATCH4 TNFRSF21 CCN1 NFX1 NGLY1

2.85e-0519313661b29525c5936d1b779253b8c20f059fa091c6127
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

E2F7 NUF2 POLA2 DDX11 CDCA2 ASPM

2.85e-051931366cf680afddc08b6481f1b3eee9c57acfaebeac6f0
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

NDNF MYO1B PTH1R WWC2 CCN1 WNK3

3.29e-05198136685f424cd9bb3117c9e322031024aabb87696ce47
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

NDNF MYO1B PTH1R WWC2 CCN1 WNK3

3.29e-0519813669b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

RASGRF2 ZBED2 CDCA2 SAMD9L MACF1 AKAP11

3.29e-051981366ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells-Neuroepithelial_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

E2F7 NUF2 POLA2 CDCA2 FAM111A ASPM

3.48e-052001366203b9a5de4430713da01b3331e69381db449a3a0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Stem_cells|GW26 / Sample Type, Dataset, Time_group, and Cell type.

E2F7 NUF2 POLA2 CDCA2 FAM111A ASPM

3.48e-052001366a854e19703dc920e48304541e2b06ed013292f3e
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FOXS1 TFPI2 PTH1R SLC16A12 NODAL

5.93e-051351365e908aacb72a8c340f06cf5b4a6b70c2faac4d027
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 IRF8 E2F7 GRIN2B DDX11

6.81e-051391365c9bf98bed77415a1438f3f9e441a1346e75c26b0
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

FOXS1 TFPI2 BCHE THOP1 TAFA5

1.01e-0415113658ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

E2F7 CDCA2 ZNF750 KIAA2012 GPRASP2

1.04e-041521365854c841c1fc6300b7e9be9c98cbf9b0ce2678690
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A RASGRF2 NUF2 RET ASPM

1.14e-0415513658e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 MYO1B GRIN2B ITPRID1 POU2F3

1.17e-04156136558b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCellfacs-Brain_Myeloid-Cerebellum|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A NKX2-3 PTCHD1 SAMD9L PLEC

1.17e-04156136528c4fb4d2c6c47696c3a6722998f9da5a8923323
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

E2F7 NUF2 DDX11 CDCA2 ASPM

1.36e-0416113650dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

E2F7 NUF2 DDX11 CDCA2 ASPM

1.36e-041611365b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

E2F7 NUF2 DDX11 CDCA2 ASPM

1.36e-041611365efb811dda4d73107983a5f68302bdcf4f408d5b4
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

E2F7 NUF2 DDX11 CDCA2 ASPM

1.36e-04161136528d5dbd20c9f8e0069f172d552997a044790e1a7
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 MYO1B GRIN2B ITPRID1 POU2F3

1.40e-041621365ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

E2F7 NUF2 DDX11 CDCA2 ASPM

1.44e-0416313655285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_2|390C / Donor, Lineage, Cell class and subclass (all cells)

E2F7 NUF2 CDCA2 ASPM PRKAR2B

1.48e-041641365ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPAG8 POLA2 DDX11 CDCA2 ASPM

1.48e-0416413651642a67c66eeb77a218e7814e3cfe517d9822955
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPAG8 POLA2 DDX11 CDCA2 ASPM

1.48e-04164136525758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CTU2 MYO5A IRF8 MAGI2 ZNF587

1.53e-04165136576abebe80e5f8bf44825bb619ae86fcb6f66ffeb
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IPPK ARHGEF18 NGLY1 KYNU TMPRSS11A

1.57e-041661365bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IPPK ARHGEF18 NGLY1 KYNU TMPRSS11A

1.57e-0416613655e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF18 POLA2 CDCA2 ASPM POLI

1.61e-041671365754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGEF38 MYO1B GRIN2B ITPRID1 POU2F3

1.66e-0416813658072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

TTC24 IRF8 GPR52 IRF4 TNFRSF21

1.66e-04168136590f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|390C / Donor, Lineage, Cell class and subclass (all cells)

E2F7 TMEM145 ASPM PRKAR2B KYNU

1.66e-0416813652082b15fc7935a211f1c61506b305af5501a21ad
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

E2F7 NUF2 CDCA2 FAM111A ASPM

1.66e-041681365d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

ANKRD31 THSD7A DIAPH2-AS1 METTL18 WNK3

1.66e-04168136545ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

E2F7 NUF2 DDX11 CDCA2 ASPM

1.71e-041691365e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYO1B GRIN2B ITPRID1 PTCHD1 POU2F3

1.71e-04169136505e12524d68d409fed386ffad233305683b4575b
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUF2 CDCA2 FAM111A GALNT9 ASPM

1.71e-0416913654db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NKX2-3 NUF2 CCN1 GALNT9 ASPM

1.75e-041701365a7184dc41f90caa753860ed0f65a18133f84bc5f
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SAMD9L FAM111A RASGEF1B ASPM ADGRE1

1.80e-04171136541932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NUF2 DDX11 CDCA2 ASPM TAFA5

1.80e-0417113650eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCellURO-Lymphocyte-B-Plasmablast|URO / Disease, Lineage and Cell Type

TTC24 NUF2 TNFRSF21 ASPM FAM227A

1.85e-04172136548888ef50ac784b38aca81da68f8a94ce09c670d
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A PTCHD1 FAM111A MACF1 VCPIP1

1.90e-041731365869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

NDNF THSD7A ZBED2 WWC2 CCN1

1.90e-0417313653afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

E2F7 NUF2 POLA2 CDCA2 ASPM

1.90e-041731365f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A PTCHD1 FAM111A MACF1 VCPIP1

1.90e-0417313650672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A PTCHD1 FAM111A MACF1 VCPIP1

1.90e-041731365870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

E2F7 NUF2 POLA2 CDCA2 FAM111A

1.95e-041741365c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TTC24 IRF4 MYO1B RET TNFRSF21

1.95e-041741365ab654e87c7eab7f33adc61be7a86da5c4d88008d
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TTC24 IRF4 MYO1B RET TNFRSF21

1.95e-041741365d9bccff5258c4277bdd1edbd87e17c327ec125e8
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TTC24 IRF4 MYO1B RET TNFRSF21

1.95e-0417413652453419842fd22d066631615403393bfe4449bb8
ToppCell10x5'-blood-Lymphocytic_T_CD4-Tfh|blood / Manually curated celltypes from each tissue

SPAG8 GALNT11 KRTCAP3 POLI AKAP11

2.01e-041751365d7e24ac683ff36f7ce3d1151353d3d4a6f2b63bf
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

PRICKLE4 ZNF750 CPNE3 GRHL3 TMPRSS11A

2.01e-0417513650cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NUF2 DDX11 CDCA2 ASPM TAFA5

2.01e-041751365bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellBAL-Control-Myeloid-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TTC24 IRF4 MYO1B RET TNFRSF21

2.01e-0417513656d5bdfbe53608e01c3845ecd908ca6d0fecc58f8
ToppCellBAL-Control-Myeloid-pDC-pDC-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TTC24 IRF4 MYO1B RET TNFRSF21

2.01e-0417513656839ee3bb4457d13cb08ca8eb79ae33ddd256783
ToppCellBAL-Control-Myeloid-pDC-pDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TTC24 IRF4 MYO1B RET TNFRSF21

2.01e-0417513659d6135e183179968555670abec39dff9da2c3219
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

ZBED2 E2F7 NUF2 CDCA2 ASPM

2.06e-041761365a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NDNF ARHGEF28 RASGRF2 CCN1 MACF1

2.06e-041761365f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellControl-Myeloid-pDC|Control / Disease group,lineage and cell class （2021.01.30）

TTC24 IRF4 MYO1B RET TNFRSF21

2.06e-041761365baa3563973ea1a351fe028f55828463d2a51bf1a
ToppCellCF-Lymphoid-pDC|CF / Disease state, Lineage and Cell class

TTC24 IRF4 RET TNFRSF21 MTR

2.06e-041761365dd1e529a9e413bcaab43584afbe059e1464ffb53
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

E2F7 NUF2 CDCA2 ASPM GRHL3

2.06e-04176136545c6983ab671b0f306e7390320bd84f848e474cc
ToppCellAT1_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

NDNF THSD7A ZBED2 MYO1B CCN1

2.11e-0417713653128b8d04687acee1ac4190b2569d6328b98eaf3
ToppCellDividing_Macrophages-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

E2F7 NUF2 CDCA2 ASPM KYNU

2.17e-0417813656557688c6790a5bcc3b9aea5b8789cf9506b3c54
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAP1LC3A EXOC8 THOP1 CCN1 SPAG16

2.17e-0417813658151e5d73407fd9cba382b69a2bc707c81790c7f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF GRIN2B JAKMIP2 PTH1R MAGI2

2.23e-0417913657394e77e665bf16d3733df91bb12907be460ab44
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IRF8 NUF2 CDCA2 RASGEF1B ASPM

2.29e-041801365ce2fc270f9d9110c2544083f61936b0b7d3b7eb3
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

E2F7 NUF2 DDX11 CDCA2 ASPM

2.29e-041801365334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUF2 CDCA2 RASGEF1B ASPM PRKAR2B

2.29e-04180136543fd5c498a87bb078d101298b472656f3294686a
ToppCell3'_v3-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

GPT IRF8 IRF4 RET TNFRSF21

2.34e-04181136566d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF GRIN2B JAKMIP2 PTH1R MAGI2

2.34e-0418113655bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCOA3 IRF8 IRF4 RASGEF1B BOD1L1

2.34e-041811365d66838fca0429cad2079cd8d92a5cd33eb0d3522
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

DIAPH2-AS1 CDCA2 FAM111A ASPM PLEC

2.34e-041811365ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF GRIN2B JAKMIP2 PTH1R MAGI2

2.34e-0418113658e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAAF11 SPAG8 FAM227A SPAG16 KIAA2012

2.40e-041821365fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF THSD7A ZNF185 POLA2 MAGI2

2.40e-041821365cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF THSD7A ATP8B1 MAGI2 PRKAR2B

2.47e-0418313653c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF THSD7A ATP8B1 MAGI2 PRKAR2B

2.47e-0418313659c2689d76fc6d30f5ab093428aa669d0a98953cf
Diseaseegg allergy measurement, parental genotype effect measurement

GRIN2B SPATA31C1 TAFA5

2.06e-05131253EFO_0005939, EFO_0007018
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

GRIN2B PTCHD1 ADGRE1

2.25e-04281253DOID:1094 (implicated_via_orthology)
Diseaseaxial length measurement, refractive error

RASGRF2 CNTN5

2.64e-0461252EFO_0005318, MONDO_0004892
DiseaseAplasia Cutis Congenita

BMS1 PLEC

2.64e-0461252C0282160
DiseaseNRF2 measurement

NUF2 GRIN2B

4.90e-0481252EFO_0009794
Diseasehyperhomocysteinemia (implicated_via_orthology)

BCHE GRIN2B

9.55e-04111252DOID:9279 (implicated_via_orthology)
Diseasepsoriasis

ITPRID1 SPATA31C1 MYPN POLI GRHL3 POU2F3

1.11e-032731256EFO_0000676
Diseaseproto-oncogene tyrosine-protein kinase receptor Ret measurement

BMS1 RET

1.35e-03131252EFO_0008272
Diseasesilicosis (biomarker_via_orthology)

RTEL1 KIF3A

1.57e-03141252DOID:10325 (biomarker_via_orthology)
Diseasemultiple myeloma (is_implicated_in)

IRF8 IRF4 MTR

2.03e-03591253DOID:9538 (is_implicated_in)
DiseaseHallux valgus

MYO1B MTR TAFA5

2.13e-03601253HP_0001822
DiseaseHeadache

NOL4L PRKAR2B MACF1

2.56e-03641253HP_0002315
Diseasecannabis dependence

GBF1 MAGI2 NOL4L TAFA5

2.65e-031351254EFO_0007191
Diseasewheezing

SLC16A12 MAGI2 TAFA5

2.68e-03651253EFO_0009715
DiseaseColorectal Carcinoma

RASGRF2 TFPI2 MYO1B RET ITPRID1 JAKMIP2 ETAA1 PRKCE NODAL

3.07e-037021259C0009402
DiseaseCCL4 measurement

ZNHIT3 PTH1R

3.22e-03201252EFO_0004751
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

ANKRD31 GPT ATP8B1 STK35 PLEC

3.57e-032391255EFO_0010934
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

GPT MAP1LC3A MTR PRKCE

3.60e-031471254DOID:9352 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PDDAKKRAERILQAC

GPT

101

P24298
KPTQEVKRISEAREC

FAM227A

386

F5H4B4
PDCLETRSEKAKNRD

DIAPH2-AS1

81

Q14236
VDAKVSECEKGQRLR

ARHGEF18

641

Q6ZSZ5
TEIIKCLRNKDPQEI

BCHE

286

P06276
DCNKQQPILAERKRI

APLF

171

Q8IW19
NKENRFLPCEEKDVR

ADAM7

541

Q9H2U9
CVREVVQPLRNKKTD

ARHGEF38

116

Q9NXL2
VTNDNPECRLVKETR

CCN1

251

O00622
RQKKRAEQEALTGEC

ATF4

296

P18848
RSSPVEFECINEKKR

CPNE3

241

O75131
EDKQKVRDRNVIPDT

AKAP11

1086

Q9UKA4
DPKEKQTCDIRLRVR

DEDD

186

O75618
NPEDIRTNIKCDRKV

BMS1

266

Q14692
EEKAQVANRPLKCIV

CASP8AP2

1776

Q9UKL3
RENQTEINKPKAKRC

ASPM

506

Q8IZT6
KVSCKVQRGDENDIR

ATP1B4

266

Q9UN42
KEINNRTCEVIKDGR

ATP8B1

171

O43520
EKKVALNCEVRGNPV

CNTN5

116

O94779
ERKPIEVSREKSSNC

NR2C1

186

P13056
ICQPEERDAKTALVK

GSTA5

111

Q7RTV2
KQLCLKIQSERPESR

IPPK

86

Q9H8X2
KIQSERPESRCDKDL

IPPK

91

Q9H8X2
DPSFCNRQEKDVIKR

ARHGEF28

836

Q8N1W1
KRTQVDDVDCNPRKI

ANKRD31

736

Q8N7Z5
VRETEKQCKPLLERN

JAKMIP2

316

Q96AA8
RQDDKVVCPRTKEVF

MAEA

371

Q7L5Y9
SEVKARQDVKPDIRQ

MAGI2

1071

Q86UL8
QEKALACIPVQELKR

NGLY1

191

Q96IV0
RPNKLERDQTCKLFD

IRF4

346

Q15306
RRDCNPEVSESFKVK

ITPRID1

266

Q6ZRS4
NAVATCRRELPEVKK

NAIF1

56

Q69YI7
TLKKCEDVARPTQRL

GALNT9

536

Q9HCQ5
PCDQEIKELENNIRK

PRKCE

351

Q02156
TLPAEQEESRVKCKN

FAM90A27P

31

A6NNH2
DPCSRRKKRQQQEEE

GPATCH4

331

Q5T3I0
CKGRPNKLERDEVVQ

IRF8

306

Q02556
RTVIEDCNKVQEKRG

NUF2

371

Q9BZD4
RDVPDTRNAACKEKF

GALNT11

131

Q8NCW6
KRQTVEDCPRTGEKQ

PRAMEF18

131

Q5VWM3
RVLQFKKICEEAPEN

GALK2

341

Q01415
DQEKCTVRRQDPQVV

NFX1

311

Q12986
KCDLQEQRRVDPDVA

NKIRAS2

121

Q9NYR9
RCEDPSKALLTKREQ

KIAA2012

966

Q0VF49
REQNQCLGPDIRKKS

NDNF

496

Q8TB73
ENDVNEPDVKRCRKP

METTL18

241

O95568
NEKIDREQICKQSPS

PCDH10

76

Q9P2E7
EEKPKRRRQEKQAAC

DDX11

301

Q96FC9
SEKPESCDNVKVVVR

KIF3A

6

Q9Y496
KVVVRCRPLNEREKS

KIF3A

16

Q9Y496
QPKEKIQAIIESCSR

NOL4L

211

Q96MY1
KQVECPFERDRKILQ

RASGEF1B

416

Q0VAM2
SLRCEQDPEKKAFIR

EXOC8

661

Q8IYI6
QRVREAAEKAKCELS

HSPA9

306

P38646
CVKDQEAQEPKPRKR

GPR52

341

Q9Y2T5
NRRQKEKRINCPVAT

POU2F3

331

Q9UKI9
KTRPRFVKQDQVCIA

GSPT1

441

P15170
PAEVDKIRECISDNK

MACF1

5921

Q9UPN3
EEEKNRKCSPEEIQR

ETAA1

886

Q9NY74
RKCSPEEIQRKRQEA

ETAA1

891

Q9NY74
KAEAPKGQEQCRLET

PRICKLE4

276

Q2TBC4
KGQEQCRLETIRDPK

PRICKLE4

281

Q2TBC4
KKQKQRPSEERICNA

KAT6A

21

Q92794
ERSEICTEEPQKQKS

BOD1L1

681

Q8NFC6
RQPTAKQRVIDVADC

GRHL3

306

Q8TE85
VKPERLVANNEVCVK

KLHL11

306

Q9NVR0
RVGKPKNQVITACRD

BBS2

686

Q9BXC9
SAQKRLCEERKPQEE

E2F7

591

Q96AV8
AVIPQGQRAKKCQER

FAM111A

486

Q96PZ2
DNVKFRKTTDPCLQR

GRTP1

121

Q5TC63
CQKQVKAQLPRRESE

FBXO28

116

Q9NVF7
PQKKTREVAERKREC

DEFB113

21

Q30KQ7
EPQIREQEKDHCLKR

DNAAF11

166

Q86X45
LKIEVVPDCQEKRSS

MCF2

466

P10911
NTEVQPCKEKKINRR

CDCA2

526

Q69YH5
SLNECFVKVPRDDRK

FOXS1

71

O43638
TQQEKKETARPSCEI

GBF1

601

Q92538
PKTDEQRCRLQEACK

PRKAR2A

121

P13861
PKTDDQRNRLQEACK

PRKAR2B

136

P31323
RCPVKQDSVESQLKR

FAM102B

281

Q5T8I3
CAQEQRKPVRLESAE

METTL13

226

Q8N6R0
VRDAKEKCPQLVLVN

POLI

106

Q9UNA4
PEVVRDRSQKSCQLK

NKX2-3

111

Q8TAU0
RPSREQKCVKCKEAQ

CTU2

21

Q2VPK5
ELESPKCKRQENEQL

KRTCAP3

211

Q53RY4
REQLCIHPEVKKQES

RTEL1

141

Q9NZ71
ARPACVDARIIKTKQ

TAFA5

81

Q7Z5A7
CTLIRNVKPEDVKRV

PMPCA

466

Q10713
KLQKPNAAIRDCDRA

ST13P4

156

Q8IZP2
VQSKRKEATCPRHQE

TRIM31

86

Q9BZY9
CKETAEIRRQIGKQE

MRPL32

131

Q9BYC8
ICKEVQAEQEPTRKL

SPAG8

361

Q99932
KKDTVLRQVRLDPCD

TNFRSF21

581

O75509
REIACIQKDKDIPAE

THSD7A

156

Q9UPZ6
PDRSQLCRKVKFQVD

NODAL

241

Q96S42
PEQNHVCRTQKEDIK

SLC16A12

236

Q6ZSM3
RKEKKNPENREEIEC

PTCHD1

856

Q96NR3
VDNPRVDLCNKLKRS

RASGRF2

806

O14827
EINEAKKCIREPRFV

SAMD9L

276

Q8IVG5
KRQTVEDCPRTGEKQ

PRAMEF19

131

Q5SWL8
AQKDVDSDRVKQEPR

GPRASP2

366

Q96D09
IREIAEAVKNCKPRV

MTR

331

Q99707
PDKCAILKETVRQIR

NCOA3

66

Q9Y6Q9
SREDKKQVQFVSEPC

POLA2

446

Q14181
KEAQTVKFQLERDPC

SPATA31C1

506

P0DKV0
RCKEVQQIRDQHPSK

MAP1LC3A

16

Q9H492
EERKVGQPCELNITK

SUPT20HL2

271

P0C7V6
QRVLFKCKEDVIPDN

ADGRE1

316

Q14246
QEAQCDLRPKGQKRT

ZNF750

676

Q32MQ0
ARVAVKKIRCDAPEN

STK35

226

Q8TDR2
PARVVVVDCKKEAFR

TIMM50

241

Q3ZCQ8
RAEKEACQREKELPA

ZBED2

196

Q9BTP6
KDVCRLREQSQKVPR

WWC2

1151

Q6AWC2
AQCQKEPDSVRERLV

TTC24

381

A2A3L6
QTERKPNECNECRKT

ZNF334

231

Q9HCZ1
AQCEKRLKEVLQRPA

PTH1R

46

Q03431
PQSCEDRKVVNYIRK

TTI2

481

Q6NXR4
KDEEAPCKQRISVQR

ZNF587

61

Q96SQ5
PTQKGLREAREQNKC

SPAG16

291

Q8N0X2
KDEEAPCKQRISVQR

ZNF417

61

Q8TAU3
AKVVADRVQDKTCPV

THNSL1

646

Q8IYQ7
CRVKPDVVQDKETER

RRP15

146

Q9Y3B9
EPARECAQRIAEQQK

PLEC

1151

Q15149
EDIKRANKSQECLIP

VCPIP1

196

Q96JH7
FVNDTKALRRPKCAE

RET

466

P07949
EQKDDEVAIRLKVCP

ZNFX1

1606

Q9P2E3
KVPKVCRLQVSVDDQ

TFPI2

91

P48307
DRDCRSDPAQQKRKI

ZFAND2B

81

Q8WV99
QEKVQKDSLRPEAAR

THOP1

126

P52888
TIQEKDRDGCPKIVN

PHF5A

76

Q7RTV0
QCNPETRPVEKKIRS

ZNHIT3

41

Q15649
KDKEAPCSRELQRDL

ZNF185

311

O15231
KDCLAKESVIRPENN

TMEM145

91

Q8NBT3
EARVKIISDDVCKQP

TMPRSS11A

326

Q6ZMR5
SRDPKVREVCVQDVK

ZNF311

176

Q5JNZ3
KRNPEKTRAQCITKE

TYW3

221

Q6IPR3
PEVKEIIEGCIRQNK

WNK3

376

Q9BYP7
QELEKRGVVCDKRNP

KYNU

416

Q16719
PTCKRKNNRLLEVAV

MYO1B

1121

O43795
EQVLRSKAKEEERPQ

MYO5A

1181

Q9Y4I1
KKDNETIPCTRERIS

MYPN

1206

Q86TC9
CQKRIVTENKTDEEP

GRIN2B

436

Q13224