Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS3 ADAMTS2 USP11 ADAM29 ADAMTS13 ADAMTS14 F2 USP15 CAPN15	7.74e-06	430	63	9	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	RELN ADAMTS3 ADAMTS2 USP11 ADAM29 ADAMTS13 ADAMTS14 F2 USP15 CAPN15	3.54e-05	654	63	10	GO:0008233
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	3.84e-05	120	63	5	GO:0004222
GeneOntologyMolecularFunction	glycosaminoglycan binding	ADAMTSL5 ADAMTS3 ACAN SMOC1 SMOC2 F2	1.98e-04	268	63	6	GO:0005539
GeneOntologyMolecularFunction	extracellular matrix structural constituent	RELN ACAN LAMB3 SSPOP FBN3	3.17e-04	188	63	5	GO:0005201
GeneOntologyMolecularFunction	heparin binding	ADAMTSL5 ADAMTS3 SMOC1 SMOC2 F2	3.49e-04	192	63	5	GO:0008201
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	4.21e-04	200	63	5	GO:0008237
GeneOntologyMolecularFunction	sulfur compound binding	ADAMTSL5 ADAMTS3 SMOC1 SMOC2 F2 SOAT1	5.35e-04	323	63	6	GO:1901681
GeneOntologyMolecularFunction	extracellular matrix binding	ADAMTSL5 SMOC1 SMOC2	1.59e-03	73	63	3	GO:0050840
GeneOntologyMolecularFunction	intramolecular oxidoreductase activity, transposing S-S bonds	PDIA4 P4HB	2.17e-03	22	63	2	GO:0016864
GeneOntologyMolecularFunction	protein disulfide isomerase activity	PDIA4 P4HB	2.17e-03	22	63	2	GO:0003756
GeneOntologyMolecularFunction	integrin binding	PDIA4 P4HB ADAMTS13 SVEP1	2.27e-03	175	63	4	GO:0005178
GeneOntologyMolecularFunction	cysteine-type endopeptidase activity	USP11 USP15 CAPN15	2.54e-03	86	63	3	GO:0004197
GeneOntologyBiologicalProcess	extracellular matrix organization	ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 ADAMTS13 ADAMTS14 SMOC1 SMOC2	2.05e-06	377	63	9	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 ADAMTS13 ADAMTS14 SMOC1 SMOC2	2.10e-06	378	63	9	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 ADAMTS13 ADAMTS14 SMOC1 SMOC2	2.14e-06	379	63	9	GO:0045229
GeneOntologyBiologicalProcess	collagen fibril organization	ADAMTS3 ADAMTS2 ACAN ADAMTS14	8.60e-05	76	63	4	GO:0030199
GeneOntologyCellularComponent	extracellular matrix	RELN ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 ADAMTS13 ADAMTS14 SMOC1 SMOC2 F2 SSPOP FBN3 SVEP1	7.07e-09	656	63	14	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	RELN ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 ADAMTS13 ADAMTS14 SMOC1 SMOC2 F2 SSPOP FBN3 SVEP1	7.35e-09	658	63	14	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	RELN ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 SMOC1 SMOC2 F2 SSPOP	3.86e-06	530	63	10	GO:0062023
GeneOntologyCellularComponent	basement membrane	ACAN LAMB3 SMOC1 SMOC2	5.04e-04	122	63	4	GO:0005604
GeneOntologyCellularComponent	microfibril	ADAMTSL5 FBN3	6.82e-04	13	63	2	GO:0001527
GeneOntologyCellularComponent	endoplasmic reticulum chaperone complex	PDIA4 P4HB	6.82e-04	13	63	2	GO:0034663
MousePheno	abnormal ductus venosus valve topology	ZMYND11 ADAMTS3 PRMT7	1.20e-05	13	50	3	MP:0013878
MousePheno	abnormal palate morphology	TBX22 BNC2 ZMYND11 ADAMTS3 ACAN SMOC1 SMOC2 DISP1	1.64e-05	321	50	8	MP:0003755
MousePheno	abnormal mouth morphology	TBX22 BNC2 ZMYND11 ADAMTS3 ADAMTS2 ACAN LAMB3 LRRK1 SMOC1 SMOC2 DISP1	1.91e-05	670	50	11	MP:0000452
MousePheno	abnormal vitelline vein topology	ZMYND11 ADAMTS3 PRMT7	6.32e-05	22	50	3	MP:0013986
MousePheno	heterochrony	ZMYND11 ADAMTS3 PRMT7	7.25e-05	23	50	3	MP:0014021
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14	1.27e-08	24	61	5	IPR013273
Domain	TSP_1	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	5.55e-08	63	61	6	PF00090
Domain	TSP1	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	6.71e-08	65	61	6	SM00209
Domain	TSP1_rpt	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	6.71e-08	65	61	6	IPR000884
Domain	TSP1	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	6.71e-08	65	61	6	PS50092
Domain	DISINTEGRIN_1	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	1.89e-07	40	61	5	PS00427
Domain	Reprolysin	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	1.89e-07	40	61	5	PF01421
Domain	ADAM_MEPRO	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	1.89e-07	40	61	5	PS50215
Domain	DISINTEGRIN_2	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	1.89e-07	40	61	5	PS50214
Domain	Peptidase_M12B	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	1.89e-07	40	61	5	IPR001590
Domain	Disintegrin_dom	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	2.15e-07	41	61	5	IPR001762
Domain	ADAM_spacer1	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS14	8.70e-07	23	61	4	IPR010294
Domain	ADAM_spacer1	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS14	8.70e-07	23	61	4	PF05986
Domain	MetalloPept_cat_dom	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	6.66e-06	81	61	5	IPR024079
Domain	-	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	6.66e-06	81	61	5	3.40.390.10
Domain	Peptidase_M12B_N	ADAMTS3 ADAMTS2 ADAM29 ADAMTS14	7.77e-06	39	61	4	IPR002870
Domain	Pep_M12B_propep	ADAMTS3 ADAMTS2 ADAM29 ADAMTS14	7.77e-06	39	61	4	PF01562
Domain	ZINC_PROTEASE	ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14	1.69e-05	98	61	5	PS00142
Domain	EGF_1	RELN LAMB3 ADAM29 SSPOP PGAP6 FBN3 SVEP1	1.90e-05	255	61	7	PS00022
Domain	EGF-like_CS	RELN LAMB3 ADAM29 ZNRF4 PGAP6 FBN3 SVEP1	2.20e-05	261	61	7	IPR013032
Domain	EGF_2	RELN LAMB3 ADAM29 SSPOP PGAP6 FBN3 SVEP1	2.43e-05	265	61	7	PS01186
Domain	PLAC	ADAMTS3 ADAMTS2 ADAMTS14	3.09e-05	19	61	3	PS50900
Domain	PLAC	ADAMTS3 ADAMTS2 ADAMTS14	3.09e-05	19	61	3	IPR010909
Domain	USP_C	USP11 USP15	3.14e-05	3	61	2	IPR029346
Domain	USP7_C2	USP11 USP15	3.14e-05	3	61	2	PF14533
Domain	Ubiquitin_3	USP11 USP15	6.27e-05	4	61	2	PF14836
Domain	Ub_USP-typ	USP11 USP15	6.27e-05	4	61	2	IPR028135
Domain	Prot_disulphide_isomerase	PDIA4 P4HB	6.27e-05	4	61	2	IPR005792
Domain	ACR	ADAM29 ADAMTS13 ADAMTS14	9.17e-05	27	61	3	SM00608
Domain	ADAM_Cys-rich	ADAM29 ADAMTS13 ADAMTS14	9.17e-05	27	61	3	IPR006586
Domain	EGF_3	RELN ADAM29 SSPOP PGAP6 FBN3 SVEP1	1.16e-04	235	61	6	PS50026
Domain	DUSP	USP11 USP15	1.56e-04	6	61	2	SM00695
Domain	DUSP	USP11 USP15	1.56e-04	6	61	2	PF06337
Domain	-	USP11 USP15	2.18e-04	7	61	2	3.30.2230.10
Domain	DUSP	USP11 USP15	2.18e-04	7	61	2	PS51283
Domain	Pept_C19_DUSP	USP11 USP15	2.18e-04	7	61	2	IPR006615
Domain	SPARC_Ca_bdg	SMOC1 SMOC2	2.90e-04	8	61	2	PF10591
Domain	SPARC/Testican_Ca-bd-dom	SMOC1 SMOC2	2.90e-04	8	61	2	IPR019577
Domain	Disulphide_isomerase	PDIA4 P4HB	2.90e-04	8	61	2	IPR005788
Domain	Thioredoxin	PDIA4 P4HB	8.00e-04	13	61	2	IPR005746
Domain	EGF-like_dom	RELN ADAM29 PGAP6 FBN3 SVEP1	1.31e-03	249	61	5	IPR000742
Domain	TY	SMOC1 SMOC2	1.38e-03	17	61	2	SM00211
Domain	-	SMOC1 SMOC2	1.38e-03	17	61	2	4.10.800.10
Domain	THYROGLOBULIN_1_2	SMOC1 SMOC2	1.38e-03	17	61	2	PS51162
Domain	Thyroglobulin_1	SMOC1 SMOC2	1.38e-03	17	61	2	IPR000716
Domain	Thyroglobulin_1	SMOC1 SMOC2	1.38e-03	17	61	2	PF00086
Domain	THYROGLOBULIN_1_1	SMOC1 SMOC2	1.38e-03	17	61	2	PS00484
Domain	Thioredoxin_CS	PDIA4 P4HB	1.38e-03	17	61	2	IPR017937
Domain	Kazal_1	SMOC1 SMOC2	2.32e-03	22	61	2	PF00050
Domain	THIOREDOXIN_1	PDIA4 P4HB	3.00e-03	25	61	2	PS00194
Domain	Galactose-bd-like	MYCBP2 LAMB3 SSPOP	3.60e-03	94	61	3	IPR008979
Domain	ZF_PHD_2	ZMYND11 ATRX KDM2A	3.71e-03	95	61	3	PS50016
Domain	hEGF	FBN3 SVEP1	3.76e-03	28	61	2	PF12661
Domain	ZF_PHD_1	ZMYND11 ATRX KDM2A	3.82e-03	96	61	3	PS01359
Domain	Thioredoxin	PDIA4 P4HB	4.59e-03	31	61	2	PF00085
Domain	Kringle-like	LY75 F2	4.89e-03	32	61	2	IPR013806
Domain	GPS	ADGRF3 ADGRF1	5.50e-03	34	61	2	SM00303
Domain	GPS	ADGRF3 ADGRF1	5.83e-03	35	61	2	PF01825
Domain	GPS	ADGRF3 ADGRF1	6.15e-03	36	61	2	PS50221
Domain	Kazal_2	SMOC1 SMOC2	6.15e-03	36	61	2	PF07648
Domain	GPS	ADGRF3 ADGRF1	6.49e-03	37	61	2	IPR000203
Domain	EGF	RELN PGAP6 FBN3 SVEP1	7.28e-03	235	61	4	SM00181
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	1.26e-09	39	41	6	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	1.26e-09	39	41	6	MM15165
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	3.96e-08	68	41	6	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTSL5 ADAMTS3 ADAMTS2 ACAN ADAMTS13 ADAMTS14 SSPOP	1.61e-07	143	41	7	M27275
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	6.71e-07	109	41	6	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	7.47e-07	111	41	6	M27416
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	ADAMTS3 ADAMTS2 P4HB ACAN LAMB3 ADAMTS14 FBN3 CAPN15	1.99e-06	300	41	8	M610
Pathway	REACTOME_COLLAGEN_FORMATION	ADAMTS3 ADAMTS2 P4HB LAMB3 ADAMTS14	5.93e-06	90	41	5	M631
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTSL5 ADAMTS3 ADAMTS2 ACAN ADAMTS13 ADAMTS14 SSPOP	6.82e-06	250	41	7	M27554
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	ADAMTS3 ADAMTS2 P4HB ADAMTS14	2.85e-05	61	41	4	MM14637
Pathway	REACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES	ADAMTS3 ADAMTS2 P4HB ADAMTS14	4.13e-05	67	41	4	M26999
Pathway	REACTOME_COLLAGEN_FORMATION	ADAMTS3 ADAMTS2 P4HB ADAMTS14	6.79e-05	76	41	4	MM14573
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	ADAMTS3 ADAMTS2 P4HB ACAN ADAMTS14 CAPN15	9.31e-05	258	41	6	MM14572
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	ACAN LAMB3 FBN3 CAPN15	7.10e-04	140	41	4	M587
Pathway	PID_THROMBIN_PAR4_PATHWAY	ROCK1 F2	8.46e-04	15	41	2	M138
Pathway	REACTOME_DISEASES_OF_HEMOSTASIS	ADAMTS13 F2	1.37e-03	19	41	2	M48230
Pathway	BIOCARTA_PAR1_PATHWAY	ROCK1 F2	1.37e-03	19	41	2	MM1514
Pathway	BIOCARTA_PAR1_PATHWAY	ROCK1 F2	1.37e-03	19	41	2	M3494
Pubmed	Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.	ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14	9.77e-12	4	63	4	22205175
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTSL5 ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14 SSPOP	5.05e-09	75	63	6	20637190
Pubmed	The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.	ADAMTS3 ADAMTS2 ADAMTS14	5.66e-09	3	63	3	25863161
Pubmed	Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.	ADAMTS3 ADAMTS2 ADAMTS14	5.66e-09	3	63	3	11741898
Pubmed	Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis.	ADAMTS3 ADAMTS2 ADAMTS14	1.13e-07	6	63	3	16556917
Pubmed	A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum.	RELN ADAMTS3 ADAMTS2	4.72e-07	9	63	3	31491533
Pubmed	ADAMTS: a novel family of extracellular matrix proteases.	ADAMTS3 ADAMTS2 ADAMTS13	6.74e-07	10	63	3	11167130
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	ADAMTS3 ADAMTS2 ADAMTS14	2.54e-06	15	63	3	38871984
Pubmed	ERp72, an abundant luminal endoplasmic reticulum protein, contains three copies of the active site sequences of protein disulfide isomerase.	PDIA4 P4HB	3.23e-06	2	63	2	2295602
Pubmed	Isolation and characterization of the mouse ubiquitin-specific protease Usp15.	USP11 USP15	3.23e-06	2	63	2	12532266
Pubmed	Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss.	SMOC1 SMOC2	3.23e-06	2	63	2	32908163
Pubmed	Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function.	ADAMTS2 ADAMTS14	3.23e-06	2	63	2	37929635
Pubmed	Characterization of SMOC-2, a modular extracellular calcium-binding protein.	SMOC1 SMOC2	3.23e-06	2	63	2	12741954
Pubmed	ADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis.	ADAMTS2 ADAMTS14	3.23e-06	2	63	2	35316211
Pubmed	Spontaneous atopic dermatitis due to immune dysregulation in mice lacking Adamts2 and 14.	ADAMTS2 ADAMTS14	3.23e-06	2	63	2	29649548
Pubmed	Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain.	ADAMTS2 ADAMTS14	9.68e-06	3	63	2	31152061
Pubmed	Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11.	USP11 USP15	9.68e-06	3	63	2	26503449
Pubmed	Induction of human ADAMTS-2 gene expression by IL-1α is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells.	ADAMTS3 ADAMTS2	9.68e-06	3	63	2	26232334
Pubmed	Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes.	SMOC1 F2	9.68e-06	3	63	2	33529332
Pubmed	IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway.	ADAMTS3 ADAMTS2	9.68e-06	3	63	2	24752352
Pubmed	Elevated expression of PDI family proteins during differentiation of mouse F9 teratocarcinoma cells.	PDIA4 P4HB	9.68e-06	3	63	2	9493907
Pubmed	Structural variability of the ubiquitin specific protease DUSP-UBL double domains.	USP11 USP15	9.68e-06	3	63	2	22001210
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZNF512B ZMYND11 ATRX MYCBP2 RNF216 ROCK1 KDM2A SVEP1	1.13e-05	591	63	8	15231748
Pubmed	LAMB3 Promotes Myofibrogenesis and Cytoskeletal Reorganization in Endometrial Stromal Cells via the RhoA/ROCK1/MYL9 Pathway.	LAMB3 ROCK1	1.93e-05	4	63	2	37801199
Pubmed	ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.	ADAMTS3 ADAMTS13	1.93e-05	4	63	2	28088271
Pubmed	ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.	ADAMTS3 ADAMTS2	1.93e-05	4	63	2	10094461
Pubmed	[ADAMTS family--new extracellular matrix degrading enzyme].	ADAMTS3 ADAMTS2	3.22e-05	5	63	2	11831030
Pubmed	A deregulated immune response to gliadin causes a decreased villus height in DQ8 transgenic mice.	ADAMTS2 LAMB3	3.22e-05	5	63	2	19795413
Pubmed	Polymorphic variation within the ADAMTS2, ADAMTS14, ADAMTS5, ADAM12 and TIMP2 genes and the risk of Achilles tendon pathology: a genetic association study.	ADAMTS2 ADAMTS14	3.22e-05	5	63	2	23491141
Pubmed	Disulphide production by Ero1α-PDI relay is rapid and effectively regulated.	PDIA4 P4HB	4.82e-05	6	63	2	20802462
Pubmed	pH dependence of the peptide thiol-disulfide oxidase activity of six members of the human protein disulfide isomerase family.	PDIA4 P4HB	4.82e-05	6	63	2	16677074
Pubmed	Glycosaminoglycans and protein disulfide isomerase-mediated reduction of HIV Env.	PDIA4 P4HB	4.82e-05	6	63	2	15644496
Pubmed	Snapshot of the interaction between HIV envelope glycoprotein 120 and protein disulfide isomerase.	PDIA4 P4HB	6.74e-05	7	63	2	20458450
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS13 ADAMTS14	6.74e-05	7	63	2	11867212
Pubmed	Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry.	PDIA4 P4HB	6.74e-05	7	63	2	12218051
Pubmed	Stability of a receptor-binding active human immunodeficiency virus type 1 recombinant gp140 trimer conferred by intermonomer disulfide bonding of the V3 loop: differential effects of protein disulfide isomerase on CD4 and coreceptor binding.	PDIA4 P4HB	6.74e-05	7	63	2	17301129
Pubmed	Comparative gene expression analysis of the engulfment and cell motility (ELMO) protein family in the mouse brain.	RELN ELMO3	6.74e-05	7	63	2	31521773
Pubmed	IL-13 regulates the immune response to inhaled antigens.	LY75 IL2RG	6.74e-05	7	63	2	15944318
Pubmed	Cell-type specific requirements for thiol/disulfide exchange during HIV-1 entry and infection.	PDIA4 P4HB	6.74e-05	7	63	2	23206338
Pubmed	The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex.	RELN ADAMTS3	6.74e-05	7	63	2	32913108
Pubmed	The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain.	ADAMTS2 ACAN SMOC2	7.61e-05	45	63	3	34248495
Pubmed	Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.	ADGRF3 ADGRF1	8.98e-05	8	63	2	12435584
Pubmed	USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor.	USP11 USP15	8.98e-05	8	63	2	22706160
Pubmed	Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusion.	PDIA4 P4HB	8.98e-05	8	63	2	12218052
Pubmed	Proteins of the PDI family: unpredicted non-ER locations and functions.	PDIA4 P4HB	8.98e-05	8	63	2	12384992
Pubmed	Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.	RELN ACAN	8.98e-05	8	63	2	11856531
Pubmed	Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins.	ATRX SVEP1	8.98e-05	8	63	2	15522233
Pubmed	Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.	RELN ADAMTS3	8.98e-05	8	63	2	28213441
Pubmed	SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors.	SMOC1 SMOC2	8.98e-05	8	63	2	21349332
Pubmed	Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2.	SMOC1 SMOC2	1.15e-04	9	63	2	34667264
Pubmed	Radial glia regulate Cajal-Retzius cell positioning in the early embryonic cerebral cortex.	RELN ACAN	1.15e-04	9	63	2	21185282
Pubmed	Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.	SMOC1 SMOC2	1.44e-04	10	63	2	19842175
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	RELN MYCBP2	1.76e-04	11	63	2	23968836
Pubmed	ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex.	RELN ACAN	1.76e-04	11	63	2	27909010
Pubmed	USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.	MYCBP2 USP11	2.11e-04	12	63	2	29293652
Pubmed	Mapping of three members of the mouse protein disulfide isomerase family.	PDIA4 P4HB	2.11e-04	12	63	2	9457688
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS2 ADAMTS13	2.11e-04	12	63	2	25770910
Pubmed	Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.	MYCBP2 USP11 USP15	2.28e-04	65	63	3	28276505
Pubmed	A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.	PDIA4 P4HB	2.90e-04	14	63	2	12475965
Pubmed	Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.	ZNF512B ATRX KDM2A	3.09e-04	72	63	3	31248990
Pubmed	Deubiquitinating enzymes: a new class of biological regulators.	USP11 USP15	3.34e-04	15	63	2	9827704
Pubmed	Genetic dissection of plexin signaling in vivo.	RELN ACAN	3.34e-04	15	63	2	24469813
Pubmed	A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes.	PDIA4 P4HB	3.34e-04	15	63	2	34487921
Pubmed	A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice.	RELN ADAMTS3	3.81e-04	16	63	2	31680851
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	GPR137C ADGRF3 ADGRF1	4.06e-04	79	63	3	12679517
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	LAMB3 SMOC1 SMOC2	4.06e-04	79	63	3	18757743
Pubmed	ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.	ADAMTS3 ADAMTS2	4.32e-04	17	63	2	10464288
Pubmed	Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity.	USP11 USP15	4.32e-04	17	63	2	29299163
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	PDIA4 BNC2 ADAMTS3 ACAN	4.67e-04	198	63	4	20881960
Pubmed	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	GARNL3 SVEP1	5.41e-04	19	63	2	18711365
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	MYCBP2 P4HB USP11 TTC27	5.72e-04	209	63	4	26389662
Pubmed	USP15 Deubiquitinates TUT1 Associated with RNA Metabolism and Maintains Cerebellar Homeostasis.	MYCBP2 USP15	6.63e-04	21	63	2	32839293
Pubmed	CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.	PTPRH ROCK1	7.29e-04	22	63	2	34187934
Pubmed	Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53.	RELN ATRX	7.29e-04	22	63	2	19020049
Pubmed	Mapping wild-type and R345W fibulin-3 intracellular interactomes.	PDIA4 P4HB	7.29e-04	22	63	2	27777122
Pubmed	USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.	USP11 USP15	7.29e-04	22	63	2	24850914
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	TCAF1 USP11 RNF216 PRMT7 USP15 CAPN15	7.86e-04	604	63	6	38803224
Pubmed	Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.	ADAMTS3 ADAMTS2	8.69e-04	24	63	2	29791855
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	ADAMTS3 PRMT7 DENND4C	8.80e-04	103	63	3	29539633
Pubmed	Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction.	LAMB3 SMOC1 LY75	9.31e-04	105	63	3	24667918
Pubmed	ERp57 is essential for efficient folding of glycoproteins sharing common structural domains.	PDIA4 LAMB3	9.43e-04	25	63	2	17170699
Pubmed	Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis.	ACAN DISP1	9.43e-04	25	63	2	29475039
Pubmed	Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors.	RELN ACAN	9.43e-04	25	63	2	31665922
Pubmed	Germline Saturation Mutagenesis Induces Skeletal Phenotypes in Mice.	ACAN LRRK1	1.02e-03	26	63	2	33905568
Pubmed	Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.	SMOC1 SMOC2	1.02e-03	26	63	2	36178190
Pubmed	Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.	RELN ROCK1	1.02e-03	26	63	2	17875933
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ZNF512B MYCBP2 ROCK1 KDM2A USP15 DENND4C	1.10e-03	645	63	6	25281560
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	ATRX CATSPERB SMOC2	1.15e-03	113	63	3	34474245
Pubmed	Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes.	PDIA4 P4HB TTC27 USP15	1.23e-03	257	63	4	31046837
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRF3 ADGRF1	1.27e-03	29	63	2	15203201
Pubmed	Proteomic analysis of early melanosomes: identification of novel melanosomal proteins.	PDIA4 P4HB	1.27e-03	29	63	2	12643545
Pubmed	Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.	ZMYND11 MYCBP2	1.45e-03	31	63	2	27321927
Pubmed	Genome-wide association study of lung function decline in adults with and without asthma.	USP15 SVEP1	1.55e-03	32	63	2	22424883
Pubmed	Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.	USP11 USP15	1.64e-03	33	63	2	30323974
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRF3 ADGRF1	1.64e-03	33	63	2	25713288
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	USP11 ROCK1 USP15	1.68e-03	129	63	3	23022380
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	TCAF1 USP11 RNF216 USP15 CAPN15	1.80e-03	481	63	5	28190767
Interaction	VWF interactions	ZNF512B PDIA4 P4HB ADAMTS13	2.56e-06	32	61	4	int:VWF
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS3 ADAMTS2 ADAMTS13 ADAMTS14	1.15e-07	19	44	4	50
GeneFamily	Adhesion G protein-coupled receptors, subfamily F	ADGRF3 ADGRF1	5.76e-05	5	44	2	916
GeneFamily	SPARC family	SMOC1 SMOC2	1.61e-04	8	44	2	1278
GeneFamily	Protein disulfide isomerases	PDIA4 P4HB	1.18e-03	21	44	2	692
Coexpression	NABA_MATRISOME	RELN ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 ADAM29 ADAMTS13 ADAMTS14 SMOC1 SMOC2 F2 SSPOP FBN3 SVEP1	1.16e-08	1026	62	15	M5889
Coexpression	NABA_MATRISOME	RELN ADAMTSL5 ADAMTS3 ADAMTS2 ACAN LAMB3 ADAM29 ADAMTS13 ADAMTS14 SMOC1 SMOC2 F2 SSPOP SVEP1	7.35e-08	1008	62	14	MM17056
Coexpression	NABA_CORE_MATRISOME	RELN ACAN LAMB3 SMOC1 SMOC2 SSPOP FBN3 SVEP1	2.75e-07	275	62	8	M5884
Coexpression	NABA_ECM_GLYCOPROTEINS	RELN LAMB3 SMOC1 SMOC2 SSPOP FBN3 SVEP1	4.08e-07	196	62	7	M3008
Coexpression	NABA_ECM_REGULATORS	ADAMTSL5 ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14 F2	1.50e-06	238	62	7	M3468
Coexpression	NABA_ECM_REGULATORS	ADAMTSL5 ADAMTS3 ADAMTS2 ADAM29 ADAMTS13 ADAMTS14 F2	1.67e-06	242	62	7	MM17062
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_DN	TMEM169 ADAMTSL5 ACAN KBTBD11 PDCD2L SSPOP	2.90e-06	168	62	6	M2991
Coexpression	NABA_CORE_MATRISOME	RELN ACAN LAMB3 SMOC1 SMOC2 SSPOP SVEP1	3.45e-06	270	62	7	MM17057
Coexpression	NABA_ECM_GLYCOPROTEINS	RELN LAMB3 SMOC1 SMOC2 SSPOP SVEP1	6.06e-06	191	62	6	MM17059
Coexpression	GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP	ZNF512B USP11 KDM2A RGS9 PGAP6 CAPN15	6.83e-06	195	62	6	M3400
Coexpression	GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP	MYCBP2 C15orf61 RNF216 DISP1 CAPN15	1.12e-04	200	62	5	M4884
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	RELN ADAMTS2 ACAN SMOC2 SLC30A10	1.41e-04	210	62	5	M2010
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	RELN ADAMTS2 ACAN SMOC2 SLC30A10	1.64e-04	217	62	5	MM861
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3	BNC2 RELN ADAMTSL5 ADAMTS2 LRRK1 SMOC1 SMOC2 LY75 SLC30A10 SVEP1	1.98e-04	1074	62	10	M1941
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ADAMTSL5 ADAMTS2 RGS9 ADAMTS13 SMOC2	2.49e-07	185	63	6	f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ADAMTSL5 ADAMTS2 RGS9 ADAMTS13 SMOC2	2.49e-07	185	63	6	40e958511790e84321da5ccf735f9974c06a0263
ToppCell	droplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ADAMTSL5 ADAMTS2 RGS9 ADAMTS13 SMOC2	2.49e-07	185	63	6	5f2eeba80aff145e85cfd81e2890a155406badb9
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KCNMB2 TMEM169 TTC27 RGS9 DISP1	4.15e-06	169	63	5	8f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	RELN KBTBD11 LRCOL1 SMOC1 SSPOP	4.53e-06	172	63	5	c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 C15orf61 TTC27 PDCD2L SMOC2	4.65e-06	173	63	5	ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	4.65e-06	173	63	5	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	COVID-19-Heart-Lymph_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	5.20e-06	177	63	5	326fde0734ef0d7272693966d346ca479b9d8147
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNMB2 RELN SMOC1 FBN3 SVEP1	5.35e-06	178	63	5	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SMOC1 SMOC2 FBN3 SVEP1	5.50e-06	179	63	5	cd7f0e8f4abb2a2bac366c8910c8c5fda841dbce
ToppCell	COVID-19-Heart-Lymph_EC\|Heart / Disease (COVID-19 only), tissue and cell type	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	5.50e-06	179	63	5	411620201a860716a8773b92f50f7b94ef34a586
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SMOC1 SMOC2 FBN3 SVEP1	5.65e-06	180	63	5	c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRH ADAMTS2 GGN SMOC2 SVEP1	5.80e-06	181	63	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRH ADAMTS2 GGN SMOC2 SVEP1	5.80e-06	181	63	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	6.80e-06	187	63	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	6.97e-06	188	63	5	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	6.97e-06	188	63	5	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-chondrocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TBX22 BNC2 ACAN SMOC1 SMOC2	6.97e-06	188	63	5	5a89587ee6f2b4dc14244bd88bb31efb81c50dbe
ToppCell	COVID-19-lung-Lymphatic_EC\|lung / Disease (COVID-19 only), tissue and cell type	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	7.16e-06	189	63	5	c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 DUSP15 ADGRF1 FBN3 SVEP1	7.34e-06	190	63	5	bb3b396d78887d5d6f93a05c8ed4d703591bf33f
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	7.34e-06	190	63	5	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BNC2 ADAMTS3 ADAMTS2 LRRK1 SMOC2	7.34e-06	190	63	5	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SMOC1 SMOC2 FBN3 SVEP1	7.72e-06	192	63	5	025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BNC2 TCAF1 GPR137C SLC30A10 DISP1	7.72e-06	192	63	5	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	COVID-19-lung-Lymphatic_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RELN KBTBD11 CATSPERB LRCOL1 SMOC1	7.72e-06	192	63	5	cbe57cda44232b183821ac633b60a2668265e616
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BNC2 ADAMTS2 ZBTB47 SMOC2 SVEP1	7.72e-06	192	63	5	f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL5 ADAMTS3 ADAMTS2 SMOC2 SVEP1	7.92e-06	193	63	5	59b8186d0221fba06a16157e9d148399ed801f38
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KCNMB2 BNC2 RELN ADAMTS2 SMOC2	7.92e-06	193	63	5	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL5 ADAMTS3 ADAMTS2 SMOC2 SVEP1	7.92e-06	193	63	5	dc92680b4bb9fc26430c92e03adb839c8c3b3b98
ToppCell	droplet-Pancreas-Endocrine-21m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTSL5 ADAMTS3 ADAMTS2 SMOC2 SVEP1	7.92e-06	193	63	5	03678162648bd5b1d65a5450b60c8863edbf95c7
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 ADAMTS3 CATSPERB SMOC2 SVEP1	7.92e-06	193	63	5	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RELN KBTBD11 LRCOL1 SMOC1 SSPOP	8.97e-06	198	63	5	05429f18e1d74880c1835568c86177f661b3477a
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RELN KBTBD11 LRCOL1 SMOC1 SSPOP	8.97e-06	198	63	5	306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATRX MYCBP2 ROCK1 KDM2A USP15	9.41e-06	200	63	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 SMOC1 ADGRF1 FBN3	6.39e-05	152	63	4	9391b46a441cf031665df1d142e3f65e98675eeb
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KCNMB2 ELMO3 ACAN SMOC1	6.55e-05	153	63	4	61fe71e32fc9c8cad875bc087aad0b0ff680bf45
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRH ADAMTS3 RGS9 LY75	7.79e-05	160	63	4	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	NS-critical-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	BNC2 ADAMTS3 DUSP15 ADAMTS14	7.79e-05	160	63	4	c61869d9dbba250270e59366e15af204e5b4395d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 SMOC1 ADGRF1 FBN3	7.79e-05	160	63	4	1e210e526ea4d84fc58a798a26c0929bcb69fd89
ToppCell	Bronchial_Biopsy-Endothelial-Lymphatic\|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X	RELN KBTBD11 SMOC1 SSPOP	8.37e-05	163	63	4	961c3a1303108afd680365466045f3460a30a7b0
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 DUSP15 ADGRF1 FBN3	8.78e-05	165	63	4	a6c6de17fec678ad0cac3138dde3a14cc39ffd26
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRH ADAMTSL5 KBTBD11 SLC30A10	8.78e-05	165	63	4	ce79d217df88035457cd58f679e72dd98722ae22
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRH ADAMTSL5 KBTBD11 SLC30A10	8.98e-05	166	63	4	22b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SMOC1 FBN3 SVEP1	9.41e-05	168	63	4	11ab08e373abe4bbd0f2134db38a2e8efa0eb159
ToppCell	Endothelial-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	RELN KBTBD11 LRCOL1 SMOC1	9.63e-05	169	63	4	8889c9e8af1ab0b093d57b69abd80b59b3461be9
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tmem132c_(SN/VTA_(SNr))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTPRH GGN ADGRF1	9.79e-05	63	63	3	e1b68ef6123ad084ce602b09fd1ba394785797e5
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tmem132c_(SN/VTA_(SNr))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTPRH GGN ADGRF1	9.79e-05	63	63	3	9bfd9ba1335a155ed9e56dd41dd3621b37d4234e
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Tmem132c_(SN/VTA_(SNr))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PTPRH GGN ADGRF1	9.79e-05	63	63	3	9a90c761898618fc7e5e2984baa1021b74d4ac39
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRH KBTBD11 LAMB3 SLC30A10	1.01e-04	171	63	4	5d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRH KBTBD11 LAMB3 SLC30A10	1.01e-04	171	63	4	e7dbee63cc39230aa12e7868ec78a129160c0d22
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Enterocyte\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRH KBTBD11 LAMB3 SLC30A10	1.01e-04	171	63	4	b0d616699e2110ffd6cf1868ed1f1a29f824e1fc
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS3 LRCOL1 DUSP15 ADAMTS14	1.03e-04	172	63	4	afa36501d48b1456c511fa0d5d326ec05bdc380f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SMOC1 SMOC2 FBN3 SVEP1	1.10e-04	175	63	4	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 SMOC1 ADGRF1 FBN3	1.10e-04	175	63	4	1d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS3 RGS9 ADAMTS13 DISP1	1.13e-04	176	63	4	a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRH KBTBD11 LAMB3 SLC30A10	1.13e-04	176	63	4	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GGN ADAMTS13 LY75 SVEP1	1.15e-04	177	63	4	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GGN USP11 LAMB3 SMOC2	1.15e-04	177	63	4	8c6d8a1c469346e66f9095d86b4615f8fc611362
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 DUSP15 ADGRF1 FBN3	1.15e-04	177	63	4	8e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNMB2 RELN FBN3 SVEP1	1.15e-04	177	63	4	d7976eac7e27044f6a859cc0c3398d08576e8c01
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN KBTBD11 LRCOL1 FBN3	1.15e-04	177	63	4	b1775e05c28883a15c56628028770bc59d3233fb
ToppCell	droplet-Spleen-SPLEEN-1m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDIA4 RELN ADAMTSL5 SSPOP	1.18e-04	178	63	4	b902059c3f861108fc64cbdc05e6f44378f5be2c
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 ADAMTS3 ADAMTS2 SVEP1	1.23e-04	180	63	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 ADAMTS3 ADAMTS2 SVEP1	1.23e-04	180	63	4	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	RELN KBTBD11 LRCOL1 SMOC1	1.25e-04	181	63	4	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	RELN KBTBD11 LRCOL1 SMOC1	1.25e-04	181	63	4	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNMB2 SMOC1 FBN3 SVEP1	1.28e-04	182	63	4	724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MYCBP2 KBTBD11 LY75	1.28e-04	182	63	4	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX MYCBP2 KBTBD11 LY75	1.28e-04	182	63	4	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	cellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LRRK1 SMOC1 LY75 IL2RG	1.31e-04	183	63	4	e01dacb08a9c36cf09c0b6764ce032a7232d4cdc
ToppCell	(6)_Endothelial-F_(Lymphatics)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	RELN KBTBD11 LRCOL1 SMOC1	1.34e-04	184	63	4	03ea613e00b45c81b752c14505a0538d698f551e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS2 SMOC1 SMOC2 SVEP1	1.34e-04	184	63	4	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SMOC1 FBN3 SVEP1	1.34e-04	184	63	4	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 ADAMTS3 ADAMTS2 SVEP1	1.36e-04	185	63	4	9faa35ceb89ccd2979072286f063687c9f846ce3
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 TCAF1 ADAMTS13 SMOC2	1.36e-04	185	63	4	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SMOC1 FBN3 SVEP1	1.36e-04	185	63	4	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	BNC2 ADAMTS2 SMOC2 SVEP1	1.36e-04	185	63	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RELN KBTBD11 CATSPERB SMOC1	1.36e-04	185	63	4	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RELN KBTBD11 CATSPERB SMOC1	1.36e-04	185	63	4	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	Endoth-Lymph\|World / shred by cell class for parenchyma	RELN KBTBD11 LRCOL1 SMOC1	1.36e-04	185	63	4	97a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 SMOC1 ADGRF1 FBN3	1.39e-04	186	63	4	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	(4)_Lymph_vessel\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	RELN KBTBD11 LRCOL1 SMOC1	1.39e-04	186	63	4	6b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCell	343B-Endothelial_cells-Endothelial-F_(Lymphatics)\|343B / Donor, Lineage, Cell class and subclass (all cells)	RELN KBTBD11 LRCOL1 SMOC1	1.39e-04	186	63	4	7a8da2ad140bea3207bd868212cc5e201d586772
ToppCell	343B-Endothelial_cells-Endothelial-F_(Lymphatics)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	RELN KBTBD11 LRCOL1 SMOC1	1.39e-04	186	63	4	dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS2 ACAN SMOC2 SVEP1	1.42e-04	187	63	4	f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS2 ACAN SMOC2 SVEP1	1.42e-04	187	63	4	02e7246ef5ad41773d14426254e139b156d45c1d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 DUSP15 ADGRF1 FBN3	1.42e-04	187	63	4	7b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCell	10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ADAMTS2 ACAN SMOC2 SVEP1	1.42e-04	187	63	4	08c73d125e0638c9e9878165bba2442c266c8a48
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRMT7 IL2RG SSPOP PGAP6	1.42e-04	187	63	4	8c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAMTS2 DUSP15 SMOC1 SMOC2	1.42e-04	187	63	4	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CCDC168 IL2RG SSPOP CAPN15	1.42e-04	187	63	4	f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TCAF1 GPR137C SLC30A10 DISP1	1.42e-04	187	63	4	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN SMOC1 FBN3 SVEP1	1.45e-04	188	63	4	c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 SMOC1 SMOC2 SVEP1	1.45e-04	188	63	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)\|390C / Donor, Lineage, Cell class and subclass (all cells)	RELN KBTBD11 LRCOL1 SMOC1	1.45e-04	188	63	4	aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	BNC2 ADAMTS3 SMOC2 SVEP1	1.45e-04	188	63	4	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	Endothelial-B-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	RELN KBTBD11 LRCOL1 DUSP15	1.45e-04	188	63	4	ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCell	390C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	RELN KBTBD11 LRCOL1 SMOC1	1.45e-04	188	63	4	1f40b959777d18ad88d239df8cca304f062ba04c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA5 SMOC1 ADGRF1 FBN3	1.45e-04	188	63	4	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ACAN LAMB3 SMOC2 SVEP1	1.45e-04	188	63	4	c9270517e6940e9793586f67f02431210552f278
Disease	body fat distribution	BNC2 ADAMTS3 ADAMTS2 ACAN KDM2A ADAMTS14	3.88e-06	202	61	6	EFO_0004341
Disease	disseminated intravascular coagulation (is_marker_for)	ADAMTS13 F2	1.87e-04	10	61	2	DOID:11247 (is_marker_for)
Disease	anthropometric measurement	BNC2 ADAMTS3 MYCBP2 KDM2A	4.11e-04	168	61	4	EFO_0004302
Disease	liver cirrhosis (is_marker_for)	RELN ADAMTS13 F2	6.63e-04	82	61	3	DOID:5082 (is_marker_for)
Disease	HVA measurement	GARNL3 DENND4C	1.32e-03	26	61	2	EFO_0005131
Disease	lung small cell carcinoma (is_implicated_in)	ATRX LAMB3	1.53e-03	28	61	2	DOID:5409 (is_implicated_in)
Disease	cortical thickness	BNC2 RELN ADAMTS3 ADAMTS2 MYCBP2 SMOC2 USP15 SOAT1	2.00e-03	1113	61	8	EFO_0004840

Protein segments in the cluster

Peptide	Gene	Start	Entry
FPKSLVWLFSPFCHC	ABCA5	351	Q8WWZ7
HCHCNYLWDPPNCLI	ADAM29	641	Q9UKF5
QWNTSICLHYPPCQS	ADGRF3	186	Q8IZF5
KPCNYWFQHDDSPSL	CATSPERB	716	Q9H7T0
WFPPSCLDPQNCYLH	ADGRF1	111	Q5T601
LSEQDWPAYFKVPCC	BNC2	21	Q6ZN30
CPPGFHFWQDTEICK	FBN3	751	Q75N90
YPCCSHWSFPYKQEI	DISP1	871	Q96F81
CQAVPCPARWQYKLA	ADAMTS13	946	Q76LX8
FRTFEPCKQLWCSHP	ADAMTS14	496	Q8WXS8
PCKQLWCSHPDNPYF	ADAMTS14	501	Q8WXS8
PCKQLWCSHPDNPYF	ADAMTS2	511	O95450
DCQEKAYWLVHRCPP	RGS9	181	O75916
QCLPWRKPNGYRCSH	LRCOL1	71	A6NCL2
YAVVCCAFNHWGPPL	CAPN15	891	O75808
CGPDCWKLSQYPCLQ	KCNMB2	101	Q9Y691
QYVPCPVCETAWAQH	LRRK1	1161	Q38SD2
FFPHWLLYCFPSCLQ	GPR137C	121	Q8N3F9
VYTCEKSCWPPNHQT	PDCD2L	326	Q9BRP1
TPWIPFQNCCYNFII	LY75	1246	O60449
SPWCQNPYVSAHPYC	LMNTD1	331	Q8N9Z9
PWACSQKFPCHYQIC	PGAP6	746	Q9HCN3
EFYAPWCGHCKQLAP	P4HB	391	P07237
RHWLPFQVLNSCPCK	GGN	581	Q86UU5
KTYQWVPFHGAPNQC	ADAMTSL5	121	Q6ZMM2
EWNDVPCNYHLPFTC	ACAN	2426	P16112
WNYLVPQCLPADPKC	RELN	2786	P78509
NQWYCYICHPEPLLD	ATRX	261	P46100
PCKQLWCSHPDNPYF	ADAMTS3	501	O15072
LPNCWECPKCYQEDS	KDM2A	666	Q9Y2K7
WNPHCKQAVYFFSPA	PRMT7	641	Q9NVM4
WSPDPKYQICLCFGE	DUSP15	211	Q9H1R2
NPPQWAKCLFSHCYS	DENND4C	766	Q5VZ89
LWFCCLSPNHKLLQY	ELMO3	561	Q96BJ8
CNVNPCCAVWEYQKP	DEFB113	56	Q30KQ7
CNQHSPYWAPPCYTL	IL2RG	351	P31785
NVVGPKCDQCAPYHW	LAMB3	456	Q13751
NFWEHISCPQKYPCL	CCDC168	3401	Q8NDH2
KEPWEPQCFCSNFPH	GARNL3	476	Q5VVW2
EWYARQHCPLKNPTF	SOAT1	521	P35610
LCHAEVPPQQHYEWC	SSPOP	1216	A2VEC9
VPPQQHYEWCLYDAC	SSPOP	1221	A2VEC9
PPHTTEATCNLWCVY	TCAF1	771	Q9Y4C2
HSFYPTPALQWACLC	MYCBP2	1551	O75592
FYAPWCGHCKQFAPE	PDIA4	86	P13667
YAPWCGHCKQLEPVY	PDIA4	551	P13667
CWLDHPYFQSLNQQP	RNF216	171	Q9NWF9
YCLNQGQWTQPLPHC	SVEP1	1671	Q4LDE5
RYHCLAKQWSPCVAP	KBTBD11	526	O94819
PFIKYHCSKAPWQDL	C15orf61	86	A6NNL5
PLKSEDPCNWQCYID	SLC30A10	266	Q6XR72
DPCNWQCYIDPSLTV	SLC30A10	271	Q6XR72
LYKPVQCHQSTGYCW	SMOC1	256	Q9H4F8
YKPVQCHPSTGYCWC	SMOC2	246	Q9H3U7
LCYKICPTNFWQQQP	TBX22	371	Q9Y458
YHCKCIDPWFSQAPR	ZNRF4	331	Q8WWF5
PWYCPNCKEHQQATK	USP15	806	Q9Y4E8
HPCQKCPRVFNNRWY	ZBTB47	436	Q9UFB7
YHFPANCDACAKPLW	ROCK1	1236	Q13464
NCDACAKPLWHVFKP	ROCK1	1241	Q13464
WCHCTSSQYPFKHPN	nan	156	Q8NA96
KCPNSGCWLEFPSIY	ZNF512B	106	Q96KM6
NWFCYPCIPNHELVW	ZMYND11	271	Q15326
HCLLYPPWDKNFTEN	F2	406	P00734
NVCYKELCGPWPSHQ	THOC5	606	Q13769
WHKISYCPCLVLFYP	TMEM169	201	Q96HH4
ERLKIFYCCQVPPHW	TTC27	426	Q6P3X3
FYCCQVPPHWAIQRQ	TTC27	431	Q6P3X3
RVKCEHYWPLDSQPC	PTPRH	926	Q9HD43
KENPWYCPSCKQHQL	USP11	796	P51784