Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	positive regulation of mRNA splicing, via spliceosome	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1C RBMY1F	3.16e-06	44	192	6	GO:0048026
GeneOntologyBiologicalProcess	response to histamine	GABRB1 GABRB2 GABRB3 CRACR2A	3.40e-06	12	192	4	GO:0034776
GeneOntologyBiologicalProcess	positive regulation of mRNA processing	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1C RBMY1F	6.03e-06	49	192	6	GO:0050685
GeneOntologyBiologicalProcess	positive regulation of RNA splicing	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1C RBMY1F	2.63e-05	63	192	6	GO:0033120
GeneOntologyBiologicalProcess	cellular response to histamine	GABRB1 GABRB2 GABRB3	2.70e-05	7	192	3	GO:0071420
GeneOntologyCellularComponent	spliceosomal complex	RBMY1D RBMY1B RBMY1E TFIP11 DDX46 CDC40 YJU2B RBMY1A1 RBMY1C RBMY1F	3.72e-05	215	196	10	GO:0005681
Domain	RBM1CTR	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1F	5.95e-09	8	192	5	PF08081
Domain	RBM1CTR	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1F	5.95e-09	8	192	5	IPR012604
Domain	GABAAb_rcpt	GABRB1 GABRB2 GABRB3	1.07e-06	3	192	3	IPR002289
Domain	KSR1-SAM	KSR1 KSR2	1.05e-04	2	192	2	PF13543
Domain	KSR_SAM-like_dom	KSR1 KSR2	1.05e-04	2	192	2	IPR025561
Domain	DP	TFDP1 TFDP2	3.13e-04	3	192	2	PF08781
Domain	Transcrp_activ_Zfx/Zfy-dom	ZFX ZFY	3.13e-04	3	192	2	IPR006794
Domain	Transcrpt_fac_DP	TFDP1 TFDP2	3.13e-04	3	192	2	IPR015648
Domain	Transc_factor_DP_C	TFDP1 TFDP2	3.13e-04	3	192	2	IPR014889
Domain	PCMT	PCMTD1 PCMTD2	3.13e-04	3	192	2	IPR000682
Domain	Zfx_Zfy_act	ZFX ZFY	3.13e-04	3	192	2	PF04704
Domain	DP	TFDP1 TFDP2	3.13e-04	3	192	2	SM01138
Domain	PCMT	PCMTD1 PCMTD2	3.13e-04	3	192	2	PS01279
Domain	Ser-Thr/Tyr_kinase_cat_dom	KSR1 FGFR1 KSR2 NEK7 LCK TNNI3K HCK	5.67e-04	138	192	7	IPR001245
Domain	Fumarylacetoacetase_C-rel	FAHD2B FAHD2A	6.22e-04	4	192	2	IPR011234
Domain	FAA_hydrolase	FAHD2B FAHD2A	6.22e-04	4	192	2	PF01557
Domain	DnaJ	DNAJA4 DNAJA1	6.22e-04	4	192	2	IPR012724
Domain	-	FAHD2B FAHD2A	6.22e-04	4	192	2	3.90.850.10
Domain	DnaJ_CXXCXGXG	DNAJA4 DNAJA1	6.22e-04	4	192	2	PF00684
Domain	-	DNAJA4 DNAJA1	6.22e-04	4	192	2	2.10.230.10
Domain	MAPKKKK	MAP4K3 MAP4K5	6.22e-04	4	192	2	IPR021160
Domain	ZF_CR	DNAJA4 DNAJA1	6.22e-04	4	192	2	PS51188
Pubmed	A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis.	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1C RBMY1F	2.13e-13	7	197	6	8269511
Pubmed	Structure and organization of the RBMY genes on the human Y chromosome: transposition and amplification of an ancestral autosomal hnRNPG gene.	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1C RBMY1F	2.75e-11	12	197	6	9598316
Pubmed	RBMY, a male germ cell-specific RNA-binding protein, activated in human liver cancers and transforms rodent fibroblasts.	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1F	3.31e-11	6	197	5	15184870
Pubmed	Degeneracy in human multicopy RBM (YRRM), a candidate spermatogenesis gene.	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1F	1.15e-10	7	197	5	8875892
Pubmed	Evolutionary strata on the mouse X chromosome correspond to strata on the human X chromosome.	RBMY1D RBMY1B RBMY1E RBMY1A1 ZFX ZFY	1.47e-10	15	197	6	14762062
Pubmed	Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal.	RBMY1D RBMY1B RBMY1E RBMY1A1 ZFY	3.06e-10	8	197	5	7479793
Pubmed	The role of Dby mRNA in early development of male mouse zygotes.	RBMY1D RBMY1B RBMY1E RBMY1A1 ZFY	4.25e-09	12	197	5	20543856
Pubmed	An RBM homologue maps to the mouse Y chromosome and is expressed in germ cells.	RBMY1D RBMY1B RBMY1E RBMY1A1	4.97e-09	5	197	4	8817321
Pubmed	Human RBMY regulates germline-specific splicing events by modulating the function of the serine/arginine-rich proteins 9G8 and Tra2-{beta}.	RBMY1D RBMY1B RBMY1E RBMY1A1	4.97e-09	5	197	4	20016065
Pubmed	The role of human and mouse Y chromosome genes in male infertility.	RBMY1D RBMY1B RBMY1E RBMY1A1	4.97e-09	5	197	4	11097427
Pubmed	Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability.	RBMY1D RBMY1B RBMY1E RBMY1A1	4.97e-09	5	197	4	19737860
Pubmed	Identification of target messenger RNA substrates for mouse RBMY.	RBMY1D RBMY1B RBMY1E RBMY1A1	1.48e-08	6	197	4	18492746
Pubmed	Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist.	RBMY1D RBMY1B RBMY1E RBMY1A1	1.48e-08	6	197	4	12356914
Pubmed	Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.	RBMY1D RBMY1B RBMY1E RBMY1A1	1.48e-08	6	197	4	9499427
Pubmed	The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary.	RBMY1D RBMY1B RBMY1E RBMY1A1	1.48e-08	6	197	4	18239052
Pubmed	Does Rbmy have a role in sperm development in mice?	RBMY1D RBMY1B RBMY1E RBMY1A1	1.48e-08	6	197	4	15051956
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	ZNF346 RPL32 PPAN IQGAP2 MYO5A SMC1A SRP68 GTF3C4 DDX46 CDC40 ASCC3 DNAJA1 DHX29 TARBP2 THOC1 ANXA1 CDK1 ZNF512 HERC5 FTSJ3	1.49e-08	759	197	20	35915203
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CYLD RPL32 MYO5A SRPRA TFIP11 TRIP4 NAA35 CLPB CASKIN2 DNAJA4 SCO1 ASCC3 CARS2 DNAJA1 DHX29 TARBP2 ERO1B TFDP1 SLC4A2 FAM83B AKAP9 MAP4K5 VPS35 MRPS5 OCLN ZNF512 HERC5 FTSJ3	2.62e-08	1487	197	28	33957083
Pubmed	The roles of RNA-binding proteins in spermatogenesis and male infertility.	RBMY1D RBMY1B RBMY1E RBMY1A1	3.45e-08	7	197	4	10377282
Pubmed	RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.	RBMY1D RBMY1B RBMY1E RBMY1A1	3.45e-08	7	197	4	17001072
Pubmed	Sex differences in sex chromosome gene expression in mouse brain.	RBMY1D RBMY1B RBMY1E RBMY1A1 ZFY	4.47e-08	18	197	5	12023983
Pubmed	GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.	GABRB1 GABRB2 GABRB3	1.79e-07	3	197	3	7893750
Pubmed	Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum.	GABRB1 GABRB2 GABRB3	1.79e-07	3	197	3	1282920
Pubmed	Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.	GABRB1 GABRB2 GABRB3	1.79e-07	3	197	3	11085308
Pubmed	GABAA receptor beta subunit mRNA expression in the human alcoholic brain.	GABRB1 GABRB2 GABRB3	1.79e-07	3	197	3	15337300
Pubmed	Mice with Y chromosome deletion and reduced Rbm genes on a heterozygous Dazl1 null background mimic a human azoospermic factor phenotype.	RBMY1D RBMY1B RBMY1E RBMY1A1	2.04e-07	10	197	4	10601091
Pubmed	Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.	RBMY1D RBMY1B RBMY1E RBMY1A1	2.04e-07	10	197	4	9384609
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYO5A SMC1A SRP68 TFIP11 GTF3C4 NAA35 CDC40 A2ML1 ASCC3 DNAJA1 DHX29 MRE11 MAP4K3 ANXA1 PPIL4 NEK7 IDH3B POLR3A NMD3 MAP4K5 VPS35 CCT6B CDK1 ZNF512 FTSJ3	2.24e-07	1353	197	25	29467282
Pubmed	MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.	RBMY1D RBMY1B RBMY1E MRE11 RBMY1A1	3.31e-07	26	197	5	35920200
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZNF346 RPL32 PPAN MYO5A GON4L SRP68 SRPRA TFIP11 TRIP4 METAP1 DDX46 CLPB DHCR24 ASCC3 DHX29 TARBP2 MRE11 STRN3 NEBL NSD1 ODF2 APOH FAM83B IWS1 CDYL2 MRPS5	4.10e-07	1497	197	26	31527615
Pubmed	GASZ promotes germ cell derivation from embryonic stem cells.	RBMY1D RBMY1B RBMY1E RBMY1A1	6.86e-07	13	197	4	23816659
Pubmed	RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.	RBMY1B RBMY1A1 RBMY1C RBMY1F	6.86e-07	13	197	4	10749975
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	MYO5A SRP68 DTX3L TRIP4 ASCC3 ANXA1 MRPS5 ZNF512 HERC5 FTSJ3	7.96e-07	228	197	10	30471916
Pubmed	Absence of mDazl produces a final block on germ cell development at meiosis.	RBMY1D RBMY1B RBMY1E RBMY1A1	9.56e-07	14	197	4	14611631
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	BCL2L14 RPS6KA5 SEMA3G METAP1 CES4A PLCB2 CARS2 STRN3 MAP4K3 NSD1 LCK POLR3A LRP2 PRKCQ CDK1 HCK DNAH11	1.04e-06	730	197	17	34857952
Pubmed	The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors.	GABRB1 GABRB2 GABRB3	1.78e-06	5	197	3	15198677
Pubmed	Human transcription factor protein interaction networks.	CYLD RPL32 PPAN HIVEP1 MYO5A SMC1A GON4L SRP68 TFIP11 ZNF462 DNAJA1 MRE11 LIMA1 PPIL4 TFDP1 TFDP2 AGO1 LRP2 HSD17B12 MRPS5 QSER1 ZNF512 PCCA FTSJ3	2.13e-06	1429	197	24	35140242
Pubmed	Loss of maternal Trim28 causes male-predominant early embryonic lethality.	RBMY1D RBMY1B RBMY1E RBMY1A1	2.24e-06	17	197	4	28115466
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PPAN HIVEP1 RPS6KA5 SMC1A TFIP11 GTF3C4 DDX46 DHX29 MOCOS THOC1 MRE11 STRN3 LIMA1 ODF2 ZFX IWS1 MTAP	2.29e-06	774	197	17	15302935
Pubmed	An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption.	HIF1A HBG1 HBG2	3.54e-06	6	197	3	37794190
Pubmed	The GABAA Receptor β Subunit Is Required for Inhibitory Transmission.	GABRB1 GABRB2 GABRB3	3.54e-06	6	197	3	29706582
Pubmed	Evolution of GABA(A) receptor diversity in the human genome.	GABRB1 GABRB2 GABRB3	3.54e-06	6	197	3	10023064
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	RPS6KA5 GTF3C4 KSR1 CLPB FGFR1 MAP4K3 ANXA1 NEK7 IDH3B LCK TFDP2 AGO1 AKAP9 MAP4K5 PRKAB1 ERRFI1 CDK1 HCK	4.89e-06	910	197	18	36736316
Pubmed	Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia.	GABRB1 GABRB2 GABRB3	6.16e-06	7	197	3	20843900
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CYLD PCMTD1 TRIP4 ZNF518A MALT1 KSR1 NAA35 SCO1 ASCC3 DNAJA1 TARBP2 MRE11 QTRT2 IDH3B TFDP1 TFDP2 LRP2 PCCA UNC80 FTSJ3	6.20e-06	1116	197	20	31753913
Pubmed	GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.	GABRB1 GABRB2 GABRB3	9.82e-06	8	197	3	11528422
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CYLD ZNF346 MYO5A SRP68 SRPRA TRIP4 ASCC3 DNAJA1 DHX29 THOC1 MRE11 ANXA1 PPIL4 AGO1 ZNF512	1.82e-05	724	197	15	36232890
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CYLD PPAN HIVEP1 SMC1A SRP68 CLPB PAN2 ASCC3 MRE11 STRN3 ANXA1 PPIL4 POLR3A NMD3 IWS1 USP6 VPS35 CDK1	1.86e-05	1005	197	18	19615732
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	RPS6KA5 ADGRB3 NAA35 DDX46 CLPB A2ML1 DHX29 ANXA1 ZFX ZFY IWS1 AGO1	1.91e-05	475	197	12	31040226
Pubmed	SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis.	RPL32 HBG1 HBG2	2.09e-05	10	197	3	14729577
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	GON4L SRPRA TFIP11 DOCK5 CDC40 CASKIN2 MOCOS MGRN1 MTMR12 GOLT1B POLR3A SLC4A2 HSD17B12 QSER1	2.28e-05	650	197	14	38777146
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	PPAN SMC1A SRP68 DDX46 CDC40 CLPB BZW2 PPIL4 IDH3B LCK NMD3 IWS1 VPS35 CDK1	2.40e-05	653	197	14	33742100
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	BCL2L14 PPAN IQGAP2 SRPRA DDX46 CLPB DHCR24 ASCC3 DNAJA1 DHX29 THOC1 BZW2 QTRT2 IDH3B POLR3A IWS1 VPS35 HSD17B12 MRPS5 PCMTD2 CDK1 HERC5	2.51e-05	1440	197	22	30833792
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	ZNF346 RPL32 PPAN PPIL4 IDH3B TFDP1 TFDP2 MRPS5 CDK1 ZNF512 FTSJ3	2.88e-05	417	197	11	36537216
Pubmed	The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia.	ANXA1 FPR2	3.19e-05	2	197	2	31908042
Pubmed	Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK.	KSR1 KSR2	3.19e-05	2	197	2	22801368
Pubmed	beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.	APOH LRP2	3.19e-05	2	197	2	9727058
Pubmed	Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function.	GABRB1 GABRB3	3.19e-05	2	197	2	26950270
Pubmed	Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma.	HBG1 HBG2	3.19e-05	2	197	2	6091051
Pubmed	β-cell proliferation is associated with increased A-type γ-aminobutyric acid receptor expression in pancreatectomized mice.	GABRB2 GABRB3	3.19e-05	2	197	2	23486367
Pubmed	Glucocorticoid upregulation of the annexin-A1 receptor in leukocytes.	ANXA1 FPR2	3.19e-05	2	197	2	16973129
Pubmed	Expression of the Annexin A1 and its correlation with matrix metalloproteinases and the receptor for formylated peptide-2 in diffuse astrocytic tumors.	ANXA1 FPR2	3.19e-05	2	197	2	30286327
Pubmed	An embryonic stage-specific enhancer within the murine β-globin locus mediates domain-wide histone hyperacetylation.	HBG1 HBG2	3.19e-05	2	197	2	21321362
Pubmed	Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.	ZFX ZFY	3.19e-05	2	197	2	1691708
Pubmed	Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation.	ANXA1 FPR2	3.19e-05	2	197	2	32015229
Pubmed	A study on the genotype frequency of -158 Gγ (C→T) Xmn1 polymorphism in a sickle cell trait cohort from Siwa Oasis, Egypt.	HBG1 HBG2	3.19e-05	2	197	2	29932071
Pubmed	The structure of the Zfx gene on the mouse X chromosome.	ZFX ZFY	3.19e-05	2	197	2	8188262
Pubmed	Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway.	HBG1 HBG2	3.19e-05	2	197	2	11172039
Pubmed	Fibroblast growth factor receptor 1 promotes MG63 cell proliferation and is associated with increased expression of cyclin-dependent kinase 1 in osteosarcoma.	FGFR1 CDK1	3.19e-05	2	197	2	26648125
Pubmed	Mapping the human ZFX locus to Xp21.3 by in situ hybridization.	ZFX ZFY	3.19e-05	2	197	2	2497060
Pubmed	Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.	HIF1A ANXA1	3.19e-05	2	197	2	26760764
Pubmed	Sequences of G gamma, A gamma, and beta genes of the Greek (A gamma) HPFH mutant: evidence for a distal CCAAT box mutation in the A gamma gene.	HBG1 HBG2	3.19e-05	2	197	2	2413469
Pubmed	No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.	GABRB1 GABRB2	3.19e-05	2	197	2	12196556
Pubmed	Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.	ZFX ZFY	3.19e-05	2	197	2	2041734
Pubmed	Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.	ZFX ZFY	3.19e-05	2	197	2	8318216
Pubmed	Targeting the Annexin A1-FPR2/ALX pathway for host-directed therapy in dengue disease.	ANXA1 FPR2	3.19e-05	2	197	2	35293862
Pubmed	Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins.	HBG1 HBG2	3.19e-05	2	197	2	6323438
Pubmed	Human fetal hemoglobin F 1. Acetylation status.	HBG1 HBG2	3.19e-05	2	197	2	5554303
Pubmed	Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells.	HIF1A PRKAB1	3.19e-05	2	197	2	18258605
Pubmed	Effect of HIV type 1 Tat protein on butyric acid-induced differentiation in a hematopoietic progenitor cell line.	HBG1 HBG2	3.19e-05	2	197	2	8911578
Pubmed	[Expression of Zfx in mouse testicular spermatogenic cells].	ZFX ZFY	3.19e-05	2	197	2	38602753
Pubmed	The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.	LCK HCK	3.19e-05	2	197	2	9705913
Pubmed	HIV-1 Nef disrupts membrane-microdomain-associated anterograde transport for plasma membrane delivery of selected Src family kinases.	LCK HCK	3.19e-05	2	197	2	23601552
Pubmed	Targeting the annexin 1-formyl peptide receptor 2/ALX pathway affords protection against bacterial LPS-induced pathologic changes in the murine adrenal cortex.	ANXA1 FPR2	3.19e-05	2	197	2	25818588
Pubmed	Annexin A1 counteracts chemokine-induced arterial myeloid cell recruitment.	ANXA1 FPR2	3.19e-05	2	197	2	25520364
Pubmed	Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.	ZFX ZFY	3.19e-05	2	197	2	12716983
Pubmed	GABAB1 and GABAB2 receptor subunits co-expressed in cultured human RPE cells regulate intracellular Ca2+ via Gi/o-protein and phospholipase C pathways.	GABRB1 GABRB2	3.19e-05	2	197	2	25241062
Pubmed	Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.	ZFX ZFY	3.19e-05	2	197	2	9126493
Pubmed	Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature.	ANXA1 FPR2	3.19e-05	2	197	2	21398608
Pubmed	Proteomic analysis of the palmitate-induced myotube secretome reveals involvement of the annexin A1-formyl peptide receptor 2 (FPR2) pathway in insulin resistance.	ANXA1 FPR2	3.19e-05	2	197	2	25616869
Pubmed	Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.	ZFX ZFY	3.19e-05	2	197	2	8487630
Pubmed	A novel C-T transition within the distal CCAAT motif of the G gamma-globin gene in the Japanese HPFH: implication of factor binding in elevated fetal globin expression.	HBG1 HBG2	3.19e-05	2	197	2	1698280
Pubmed	Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.	GABRB2 GABRB3	3.19e-05	2	197	2	13679430
Pubmed	Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.	LCK HCK	3.19e-05	2	197	2	10364375
Pubmed	A history of the human fetal globin gene duplication.	HBG1 HBG2	3.19e-05	2	197	2	7332928
Pubmed	Increased expression of GABA(A) receptor beta-subunits in the hippocampus of patients with temporal lobe epilepsy.	GABRB2 GABRB3	3.19e-05	2	197	2	14503638
Pubmed	Methylprednisolone up-regulates annexin A1 (ANXA1) to inhibit the inflammation, apoptosis and oxidative stress of cigarette smoke extract (CSE)-induced bronchial epithelial cells, a chronic obstructive pulmonary disease in vitro model, through the formyl peptide receptor 2 (FPR2) receptors and the adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) pathway.	ANXA1 FPR2	3.19e-05	2	197	2	35129068
Pubmed	Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes.	HBG1 HBG2	3.19e-05	2	197	2	7438203
Pubmed	Direct binding of GABAA receptor β2 and β3 subunits to gephyrin.	GABRB2 GABRB3	3.19e-05	2	197	2	23205938
Pubmed	Zfx mutation results in small animal size and reduced germ cell number in male and female mice.	ZFX ZFY	3.19e-05	2	197	2	9187153
Cytoband	Yq11.223	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1F	5.29e-05	93	197	5	Yq11.223
GeneFamily	Transcription factor Dp family	TFDP1 TFDP2	1.70e-04	3	137	2	987
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HIVEP1 ZNF613 ZNF366 ZBTB41 ZNF518A ZNF462 ZNF347 ZNF624 ZNF329 ZFX ZFY ZNF248 ZNF710 ZNF425 ZNF512	3.61e-04	718	137	15	28
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRB1 GABRB2 GABRB3	3.77e-04	19	137	3	563
GeneFamily	Mitogen-activated protein kinase kinase kinase kinases	MAP4K3 MAP4K5	5.62e-04	5	137	2	655
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	KSR1 KSR2	5.62e-04	5	137	2	1157
GeneFamily	RNA binding motif containing	RBMY1D RBMY1B RBMY1E RBMY1A1 RBMY1C PPIL4 RBMY1F	1.21e-03	213	137	7	725
GeneFamily	Hemoglobin subunits	HBG1 HBG2	2.46e-03	10	137	2	940
GeneFamily	Maestro heat like repeat containing	MROH5 MROH2A	3.00e-03	11	137	2	636
GeneFamily	Phospholipases	PLCB2 PLA2G7 PLA2G4C	3.94e-03	42	137	3	467
Coexpression	ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN	MYO5A RBMY1D RBMY1B RBMY1E ZNF462 MALT1 A2ML1 ADAMTS18 ACSS3 SELENOW KIF26B RBMY1A1 FRMPD1 HKDC1 POLR3A ZFY RADIL MTAP RBMY1F ERRFI1 OCLN HBG1 HBG2 HERC5	3.89e-08	873	195	24	M16009
Coexpression	PUJANA_BRCA_CENTERED_NETWORK	SMC1A METAP1 DDX46 MRE11 IDH3B TFDP1 TFDP2 CDK1	2.96e-06	118	195	8	M15305
Coexpression	GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP	DTX3L ITGA4 TRIP4 DOCK5 KSR1 C19orf12 MAP4K3 MAP4K5 PRKCQ	2.01e-05	200	195	9	M9455
Coexpression	ZHENG_IL22_SIGNALING_DN	PRTG RBMY1D RBMY1B RBMY1E RBMY1A1	2.08e-05	45	195	5	MM763
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000	GABRB1 GABRB3 TMEM169 HIF1A IQGAP2 MYO5A ADGRB3 DTX3L ITGA4 PCMTD1 ZNF462 ADAMTS18 ADAMTS20 ASCC3 S100PBP NEBL NRCAM KIF26B NSD1 ZFX MTAP AKAP9 MAP4K5 ASXL3	3.32e-07	818	190	24	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_500	GABRB2 GABRB3 PRTG DOCK5 ADAMTS18 PLA2G7 KIF26B ASXL3	2.81e-06	98	190	8	gudmap_developingKidney_e13.5_podocyte cells_500_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#3_top-relative-expression-ranked_1000	GABRB1 TMEM169 MYO5A ZNF462 ADAMTS18 ADAMTS20 KIF26B MTAP MAP4K5 ASXL3	1.13e-05	196	190	10	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k3_1000
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000	IQGAP2 ZBTB41 PCMTD1 DDX46 DHCR24 ADAMTS20 ASCC3 MGRN1 FASTKD1 NSD1 ZFX AKAP9	5.79e-05	339	190	12	gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	GABRB1 IQGAP2 ADGRB3 PCMTD1 ZNF462 CCDC112 ADAMTS18 ADAMTS20 FGFR1 LIMA1 ERO1B NEBL KIF26B ANXA1 APOH ZFX RADIL ASXL3 HBG2	6.44e-05	769	190	19	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 ADAMTS20 NRCAM KIF26B MROH2A ASXL3 LRP2 UNC80 DNAH11	1.22e-07	184	194	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 ADAMTS20 NRCAM KIF26B MROH2A ASXL3 LRP2 UNC80 DNAH11	1.22e-07	184	194	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 ADAMTS20 NRCAM KIF26B MROH2A ASXL3 LRP2 UNC80 DNAH11	1.22e-07	184	194	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRTG MOCOS NEBL NRCAM MAP4K3 KIF26B ASXL3 SETBP1	1.92e-06	190	194	8	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 ADGRB3 FGF14 NRCAM KSR2 SETBP1 UNC80	2.42e-06	196	194	8	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Mild-CD8+_T_activated\|Mild / Disease group and Cell class	SHFL CARD16 DTX3L ITGA4 OTOF DNAJA1 ANXA1 HERC5	2.61e-06	198	194	8	ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 ADGRB3 FGF14 NRCAM KSR2 SETBP1 UNC80	2.61e-06	198	194	8	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 ADGRB3 FGF14 NRCAM KSR2 SETBP1 UNC80	2.61e-06	198	194	8	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	PRTG CCDC168 ZNF518A ADAMTS20 AGO1 MAP4K5 ASXL3	4.16e-06	149	194	7	768877bade04ca0321593b8470b5011ad8270431
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A ITGA4 DOCK5 MOCOS PLA2G7 FPR2 LRP2	4.95e-06	153	194	7	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQGAP2 ITGA4 DOCK5 OTOF PLA2G7 ANXA1 FPR2	6.65e-06	160	194	7	1f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA4 DOCK5 FGF14 MOCOS PLA2G7 ANXA1 FPR2	8.13e-06	165	194	7	ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCell	10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PPAN ITGA4 CCDC112 CARS2 LCK TFDP2 CCT6B	1.54e-05	182	194	7	69b5cae6fe3bbb0fc60bd2f71b6cfa6cbb0b00ee
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRTG MOCOS NEBL NRCAM MAP4K3 KIF26B SETBP1	1.96e-05	189	194	7	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS20 FGF14 SELENOW KIF26B FRMPD1 PRKCQ UNC80	2.24e-05	193	194	7	4ccf984baebbb13ae916727137ce593fda7514a2
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS20 FGF14 SELENOW KIF26B FRMPD1 PRKCQ UNC80	2.24e-05	193	194	7	f27e2be497745098b5269aa799dd3d5f62d78ba7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACADL IQGAP2 UNC93A VWA5B1 NRCAM BZW2 KSR2	2.32e-05	194	194	7	69bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GABRB1 GABRB2 OTOF GNAZ ASXL3 SYT14 UNC80	2.32e-05	194	194	7	2dcc3b99dbedaf8a6916891c85091ddb79d7ee31
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	BCL2L14 HIF1A SHFL CARD16 DTX3L DNAJA1 HERC5	2.40e-05	195	194	7	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GABRB1 OTOF GNAZ USP6 ASXL3 SYT14 UNC80	2.48e-05	196	194	7	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYLD BCL2L14 SHFL ITGA4 LCK PRKCQ HERC5	2.56e-05	197	194	7	0b4fdf0131dd67a86ee3209fa66db0ca2e01a10e
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYLD BCL2L14 SHFL ITGA4 LCK PRKCQ HERC5	2.56e-05	197	194	7	b3876076684781fb8384117f2cf367d828985986
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 FGF14 NRCAM KSR2 SETBP1 UNC80	2.64e-05	198	194	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 GABRB3 FGF14 NRCAM KSR2 SETBP1 UNC80	2.64e-05	198	194	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IQGAP2 MALT1 DNAJA1 ANXA1 HKDC1 LCK HERC5	2.73e-05	199	194	7	f3cc3cda38f78d1d12d865df339d93c5fecf19f2
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IQGAP2 MALT1 DNAJA1 ANXA1 HKDC1 LCK HERC5	2.73e-05	199	194	7	c3c73c9404a73133bfad1f9ced292f5e508ef767
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	CCDC168 ZNF518A ADAMTS20 AGO1 MAP4K5 ASXL3	2.82e-05	135	194	6	3351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	CCDC112 DDX46 DHX29 NSD1 POLR3A SLC4A2 FTSJ3	2.82e-05	200	194	7	1fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	HIF1A IQGAP2 SRPRA ITGA4 DNAJA1 NSD1 AKAP9	2.82e-05	200	194	7	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	C2orf69 CARD16 GTF3C4 HKDC1 LCK PRKCQ	4.72e-05	148	194	6	80470353e12599440f711b6e107730763376d04d
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB1 DOCK5 PLA2G7 ANXA1 FPR2 POLR3A	5.47e-05	152	194	6	82a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB3 ITGA4 DHCR24 PLA2G7 ANXA1 FPR2	5.88e-05	154	194	6	1e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCB2 TFDP2 PLA2G4C SYT14 PSD4	5.99e-05	95	194	5	756d76830b8e7e8903b2bc7a39a38880be684297
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA4 DOCK5 DHCR24 PLA2G7 ANXA1 FPR2	6.55e-05	157	194	6	9d4308312301cb922f156a7b6aededc9e1c62807
Drug	SU6668	RBMY1D RBMY1B RBMY1E FGFR1 RBMY1A1 HBG1 HBG2	2.23e-06	70	194	7	CID000206042
Drug	azafagomine	RBMY1D RBMY1B RBMY1E RBMY1A1 ZFX ZFY	8.96e-06	57	194	6	CID011957435
Drug	Vistar	RBMY1D RBMY1B RBMY1E RBMY1A1 KRT37	1.30e-05	36	194	5	CID000040896
Drug	hydantoin-5-propionic acid	RBMY1D RBMY1B RBMY1E RBMY1A1	2.73e-05	21	194	4	CID000000782
Drug	2-chlorodideoxyadenosine	RBMY1D RBMY1B RBMY1E RBMY1A1 ZFY	3.16e-05	43	194	5	CID000072194
Drug	Adinazolam	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	DB00546
Drug	Fludiazepam	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	DB01567
Drug	Clotiazepam	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	DB01559
Drug	Cinolazepam	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	DB01594
Drug	Prazepam	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	DB01588
Drug	Estazolam	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	DB01215
Drug	Halazepam	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	DB00801
Drug	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane	GABRB1 GABRB2 GABRB3	3.31e-05	8	194	3	ctd:C091518
Drug	AZFd	RBMY1D RBMY1B RBMY1E RBMY1A1	3.99e-05	23	194	4	CID000196489
Drug	p11-13	RBMY1D RBMY1B RBMY1E CLPB RBMY1A1 ZFY	4.38e-05	75	194	6	CID000015759
Drug	Ethchlorvynol	GABRB1 GABRB2 GABRB3	4.93e-05	9	194	3	DB00189
Drug	Diazepam	GABRB1 GABRB2 GABRB3	4.93e-05	9	194	3	DB00829
Drug	ER-27319	ITGA4 LCK HCK	4.93e-05	9	194	3	CID009799508
Drug	Chicago sky blue 6B [2610-05-1]; Down 200; 4uM; MCF7; HT_HG-U133A	GABRB2 CYLD SMC1A SRPRA DNAJA4 ZNF329 ZFX ZNF710 CCT6B	5.28e-05	198	194	9	4971_DN
Drug	Chlordiazepoxide	GABRB1 GABRB2 GABRB3	6.99e-05	10	194	3	DB00475
Drug	Clobazam	GABRB1 GABRB2 GABRB3	6.99e-05	10	194	3	DB00349
Drug	Bromazepam	GABRB1 GABRB2 GABRB3	6.99e-05	10	194	3	DB01558
Drug	Oxazepam	GABRB1 GABRB2 GABRB3	6.99e-05	10	194	3	DB00842
Drug	Midazolam	GABRB1 GABRB2 GABRB3	6.99e-05	10	194	3	DB00683
Drug	Flurazepam	GABRB1 GABRB2 GABRB3	6.99e-05	10	194	3	DB00690
Drug	Clonazepam	GABRB1 GABRB2 GABRB3	6.99e-05	10	194	3	DB01068
Drug	phaclofen	GABRB1 GABRB2	7.22e-05	2	194	2	ctd:C052329
Drug	betamethasone valerate	USH1G ANXA1 HBG1 HBG2	8.91e-05	28	194	4	CID000016533
Drug	Alprazolam	GABRB1 GABRB2 GABRB3	9.56e-05	11	194	3	DB00404
Drug	Temazepam	GABRB1 GABRB2 GABRB3	9.56e-05	11	194	3	DB00231
Drug	Nitrazepam	GABRB1 GABRB2 GABRB3	9.56e-05	11	194	3	DB01595
Drug	Lorazepam	GABRB1 GABRB2 GABRB3	9.56e-05	11	194	3	DB00186
Drug	Triazolam	GABRB1 GABRB2 GABRB3	9.56e-05	11	194	3	DB00897
Drug	Clorazepate	GABRB1 GABRB2 GABRB3	9.56e-05	11	194	3	DB00628
Drug	Etomidate	GABRB1 GABRB2 GABRB3	9.56e-05	11	194	3	ctd:D005045
Disease	blood urea nitrogen measurement	BCL2L14 GON4L ZNF462 ASCC3 GFRAL FAM83B NMD3 MAP4K5 SETBP1 LRP2 PCMTD2 PSD4	2.36e-05	452	180	12	EFO_0004741
Disease	FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1	HBG1 HBG2	1.11e-04	3	180	2	141749
Disease	ERO1-like protein beta measurement	ERO1B APOH	1.11e-04	3	180	2	EFO_0801583
Disease	limb ischemia (biomarker_via_orthology)	HIF1A FGFR1	1.11e-04	3	180	2	DOID:0050852 (biomarker_via_orthology)
Disease	Hereditary persistence of fetal hemoglobin	HBG1 HBG2	1.11e-04	3	180	2	cv:C0019025
Disease	delta beta-thalassemia (is_implicated_in)	HBG1 HBG2	1.11e-04	3	180	2	DOID:0080773 (is_implicated_in)
Disease	Epilepsy, Cryptogenic	GABRB2 GABRB3 SMC1A SELENOW ASXL3	1.49e-04	82	180	5	C0086237
Disease	Awakening Epilepsy	GABRB2 GABRB3 SMC1A SELENOW ASXL3	1.49e-04	82	180	5	C0751111
Disease	Aura	GABRB2 GABRB3 SMC1A SELENOW ASXL3	1.49e-04	82	180	5	C0236018
Disease	FETAL HEMOGLOBIN QUANTITATIVE TRAIT LOCUS 1	HBG1 HBG2	2.20e-04	4	180	2	C1841621
Disease	Neurodevelopmental Disorders	GABRB2 GABRB3 SMC1A ASXL3 SETBP1	2.69e-04	93	180	5	C1535926
Disease	X-13431 measurement	ACADL UNC80	3.66e-04	5	180	2	EFO_0800735
Disease	Craniofacial Abnormalities	GABRB3 SRP68 FGFR1 ANXA1 SETBP1 LRP2	4.04e-04	156	180	6	C0376634
Disease	Epilepsy	GABRB2 GABRB3 SMC1A SELENOW ASXL3	5.59e-04	109	180	5	C0014544
Disease	response to antidepressant	MROH5 ADGRB3 ACSS3 ZNF248 ASXL3 HBG2	7.63e-04	176	180	6	GO_0036276
Disease	intestinal cancer (implicated_via_orthology)	MRE11 LCK HCK	9.72e-04	32	180	3	DOID:10155 (implicated_via_orthology)
Disease	triglyceride measurement, metabolic syndrome	MAP4K5 ZNF512	1.01e-03	8	180	2	EFO_0000195, EFO_0004530
Disease	glycylvaline measurement	PRKCQ DNAH11	1.01e-03	8	180	2	EFO_0021129
Disease	Head and Neck Carcinoma	CYLD FGFR1	1.61e-03	10	180	2	C3887461
Disease	calcium measurement	BCL2L14 DTX3L SEMA3G METAP1 CASKIN2 C19orf12 FGFR1 ASCC3 MAP4K3 ABCC6 MAP4K5	1.73e-03	628	180	11	EFO_0004838
Disease	ciliopathy (implicated_via_orthology)	RPGRIP1 MAP4K3 MAP4K5	1.87e-03	40	180	3	DOID:0060340 (implicated_via_orthology)
Disease	body weight	GABRB1 GABRB3 C2orf69 ZNF346 HIVEP1 RPS6KA5 ADGRB3 GON4L NRCAM KSR2 ZFX TNNI3K MAP4K5 ASXL3 SETBP1 SYT14 HSD17B12	1.91e-03	1261	180	17	EFO_0004338
Disease	hemopexin measurement	ZBTB41 NEK7	1.96e-03	11	180	2	EFO_0008149
Disease	response to radiation, breast carcinoma	SLFN14 NEBL	1.96e-03	11	180	2	EFO_0000305, GO_0009314
Disease	pars orbitalis volume measurement	ACSS3 CRACR2A	1.96e-03	11	180	2	EFO_0010320
Disease	macular retinal edema (is_marker_for)	HIF1A APOH	2.35e-03	12	180	2	DOID:4449 (is_marker_for)
Disease	lysophosphatidylcholine 16:1 measurement	MAP4K5 ZNF512	3.21e-03	14	180	2	EFO_0010358
Disease	level of Phosphatidylethanolamine (18:2_0:0) in blood serum	MAP4K5 ZNF512	3.21e-03	14	180	2	OBA_2045143
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRB1 GABRB2 GABRB3	3.35e-03	49	180	3	DOID:0060037 (implicated_via_orthology)
Disease	hepatic encephalopathy (biomarker_via_orthology)	GABRB1 HIF1A	3.69e-03	15	180	2	DOID:13413 (biomarker_via_orthology)
Disease	Hemoglobin F Disease	HBG1 HBG2	3.69e-03	15	180	2	C0019025
Disease	aspartate aminotransferase measurement	IQGAP2 ZNF366 METAP1 C19orf12 CARS2 ARL14 MOCOS CACNA1S NSD1 HKDC1 GOLT1B APOH MAP4K5	3.79e-03	904	180	13	EFO_0004736
Disease	diabetic retinopathy (implicated_via_orthology)	HIF1A ITGA4	4.20e-03	16	180	2	DOID:8947 (implicated_via_orthology)
Disease	factor VII measurement	PRTG MAP4K5 PRKCQ	4.64e-03	55	180	3	EFO_0004619
Disease	protein C measurement	FZD9 MAP4K5	4.74e-03	17	180	2	EFO_0004633
Disease	interleukin-6 measurement	OR5L2 KSR2 MTAP CDYL2	4.99e-03	112	180	4	EFO_0004810
Disease	Alzheimer's disease (implicated_via_orthology)	HIVEP1 DNAJA4 DNAJA1	5.13e-03	57	180	3	DOID:10652 (implicated_via_orthology)
Disease	Myeloid Leukemia	SMC1A SETBP1	5.31e-03	18	180	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SMC1A SETBP1	5.31e-03	18	180	2	C0023466
Disease	Autistic Disorder	GABRB1 GABRB3 ITGA4 NRCAM NSD1 AGO1	5.47e-03	261	180	6	C0004352
Disease	creatinine measurement, glomerular filtration rate	CACNA1S TFDP2 MAP4K5 LRP2	5.82e-03	117	180	4	EFO_0004518, EFO_0005208
Disease	cerebral infarction (is_marker_for)	HIF1A PLA2G7	5.91e-03	19	180	2	DOID:3526 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LHGTARGKTKMQKKL	USH1G	206	Q495M9
HVAKGKSVFLDQMKK	BZW2	386	Q9Y6E2
KKERMLQKGSGFHLD	SLC4A2	1021	P04920
TSVGHYKMVKHRGDK	B4GALT3	281	O60512
KKIKGLLRAVHNEGM	AKAP9	2941	Q99996
LSGERKMKAAVKHSG	C19orf12	26	Q9NSK7
KMKAAVKHSGKGALV	C19orf12	31	Q9NSK7
VKVRNKHKGKPTFME	CCDC112	176	Q8NEF3
KIQEKFKNGMLHGDK	APOH	281	P02749
AANKMEAGIKLLHTK	PRMT9	221	Q6P2P2
KEHKKFVQILGDLGM	C2orf69	346	Q8N8R5
ENGMKGFIKGRKLHK	ACADL	236	P28330
MRKIKSKIHGNFTHG	ADGRG4	2346	Q8IZF6
DGILDKKLKHRAGQM	ADGRB3	1051	O60242
PVGIKAGHSNKYLKM	ERO1B	106	Q86YB8
KGSLVMEGQKHLNSK	A2ML1	496	A8K2U0
KGLKVEVTHCGQMKR	AGO1	261	Q9UL18
QKGKHLSMVPGSYIK	C16orf78	111	Q8WTQ4
IKNKYGMDLKVTHLG	DNAH11	3506	Q96DT5
KLKKDKALMGHFQDG	BCL2L14	226	Q9BZR8
GKGFIARKDMQRLHK	CRACR2A	66	Q9BSW2
QGFRKLTGFVKSHMK	ARL14	166	Q8N4G2
VHVEKGMKDGQKILF	DNAJA4	211	Q8WW22
MGGKNKKHKAPAAAV	DHX29	1	Q7Z478
HIDKGMKDGQKITFH	DNAJA1	211	P31689
DKEMKHGQKSPTGKQ	ASXL3	211	Q9C0F0
ADKKMVEKHGKGNVT	ADAMTS18	301	Q8TE60
GIGIMKRQVKCITKH	ADAMTS20	1671	P59510
HVAAFKGDLGMLKKL	ANKRD42	241	Q8N9B4
TGKLQGKQHMSSIKE	NWD1	1031	Q149M9
KDMNGKSLHGKAIKV	RBMY1A1	66	P0DJD3
KDMNGKSLHGKAIKV	RBMY1B	66	A6NDE4
KDMNGKSLHGKAIKV	RBMY1C	66	P0DJD4
KDMNGKSLHGKAIKV	RBMY1D	66	P0C7P1
KDMNGKSLHGKAIKV	RBMY1E	66	A6NEQ0
KDMNGTSLHGKAIKV	RBMY1F	66	Q15415
AKKLGLRCHSKGTMV	MTAP	156	Q13126
GKVDGLKLLNNMHEK	NSD1	831	Q96L73
LMHFNLQKKRAKGKG	QSER1	1066	Q2KHR3
KHPKESRSNKDMAGK	IWS1	666	Q96ST2
KLSHIKKMVGDYDRQ	OCLN	506	Q16625
IKHKKKGTVSMVNNG	PPIL4	86	Q8WUA2
ARVVSKGKKMHLQFD	PCDHB2	66	Q9Y5E7
KGKKMHLQFDRQTGD	PCDHB2	71	Q9Y5E7
MAGYGPQKKLNLSHK	LRCOL1	21	A6NCL2
IRHGGKKMRFLVAKS	RADIL	1046	Q96JH8
KLHQAMKGVGTRHKA	ANXA1	281	P04083
MAVKKHGGEISKNKE	PAN2	766	Q504Q3
YLHSKGKMHRDIKGA	MAP4K3	126	Q8IVH8
ILHKMLGKGSFGKVF	PRKCQ	381	Q04759
QKHKMKATGFFLGGV	GOLT1B	61	Q9Y3E0
KNKAVGVMKSGHVFT	METAP1	311	P53582
SKMKVLEFVAKVHGS	MAGEB16	286	A2A368
MGGKRTKKSKHLDDE	MAGED4	341	Q96JG8
MKQRDKKVVTKTFHG	nan	211	A8MVJ9
LKASGGEIKIHKMEQ	LIMA1	291	Q9UHB6
MGKCHLTKGKQALEI	MALT1	536	Q9UDY8
KKILTFQGSKTHGML	NRCAM	901	Q92823
KLDKGQRKGMRFKHQ	MTMR12	546	Q9C0I1
YGLIAAKIHKKGMIK	FPR2	221	P25090
EMLTHRNGLVKKGKE	HIF1A	146	Q16665
GKNTLNGHEKETMKF	KRT37	96	O76014
KHMDGSFSVKPLKQK	MGRN1	226	O60291
GHAKLGKSYTMIGKD	KIF26B	546	Q2KJY2
VKGMGYLHAKGILHK	KSR2	771	Q6VAB6
LSKTGAKFHGKMEQK	FAM83B	216	Q5T0W9
KDHENYMKILLKVGG	PCMTD1	171	Q96MG8
KEHEEYMKNLLKVGG	PCMTD2	171	Q9NV79
MKIVHKKKERGHGYN	PNRC2	36	Q9NPJ4
MGYLHAKGIVHKDLK	KSR1	721	Q8IVT5
AGDLSRMIKHFKKQK	NEK7	116	Q8TDX7
TKYGTLQGKQMHVGK	CES4A	31	Q5XG92
AMKGNRVKKTKPAAH	FGF14	181	Q92915
KKKKAMTVGEYRHLA	KDM4D	91	Q6B0I6
GHTKVAVKSLKQGSM	LCK	266	P06239
DKKSFVHGVTVKNRM	GABRB1	126	P18505
KKSFVHGVTVKNRMI	GABRB2	126	P47870
DKKSFVHGVTVKNRM	GABRB3	126	P28472
KKKHGKDQLPGTMAT	MOCOS	716	Q96EN8
IGKKGKHIKATDAMA	FAHD2A	166	Q96GK7
GHDTGKLYAMKVLKK	RPS6KA5	71	O75582
SKHMIFKQKIDGTGR	LRP2	761	P98164
GFKGHMLTKSEKNQL	PCCA	511	P05165
IGVNKLGHQKKLMLG	CASKIN2	601	Q8WXE0
TGKIIGHMLKLKGDI	PLA2G7	361	Q13093
LKNGRKIHSNGRIKM	PRTG	361	Q2VWP7
VMKGNRVKKTKAAAH	FGF11	181	Q92914
IKLGKNMKIHSVDQG	HERC5	91	Q9UII4
KHGGIRDKIMSSRKH	PLA2G4C	366	Q9UP65
KIKNLGKTGDHTMDI	QTRT2	16	Q9H974
HIRKIMKTGGTNTEK	FZD9	426	O00144
YNKHTKVAVKTMKPG	HCK	281	P08631
GKVTAVHKANIMKLG	IDH3B	211	O43837
KSTIVKQMKIIHSGG	GNAZ	46	P19086
KKVTAKIDHGNRMLG	DOCK5	146	Q9H7D0
GMSSLAGKKLKEGHE	DTX3L	511	Q8TDB6
KGMALYTRKHANKIT	GFRAL	326	Q6UXV0
IGKKGKHIKATDAMA	FAHD2B	166	Q6P2I3
AIIGLELFKGKMHKT	CACNA1S	211	Q13698
KMIGKHKNIINLLGA	FGFR1	536	P11362
GKDIKKAISFHMKRN	FRMPD1	351	Q5SYB0
SLRVGKYKKTHKNIM	DHCR24	101	Q15392
MGNPKVKAHGKKVLT	HBG1	56	P69891
GKSAMKKRHLEILGY	FASTKD1	796	Q53R41
GKLHATGSKRGKKMT	GON4L	121	Q3T8J9
AKHGMKVVLISRSKD	HSD17B12	71	Q53GQ0
LNILHEMKGKKLGSY	ITGA4	291	P13612
GKTELAKQTAKYMHK	CLPB	386	Q9H078
HEKLYIMLKGKMGTV	CYP39A1	116	Q9NYL5
NHRKKMGGNFEIIIK	CCDC168	1111	Q8NDH2
HSVKEKGKLLMHFSV	CCDC168	6541	Q8NDH2
MKILNSLKKHGYEKP	DDX46	381	Q7L014
IMIGKKKGIQGHYNS	CYLD	586	Q9NQC7
MGNPKVKAHGKKVLT	HBG2	56	P69892
LNKDSGKMKGHERRL	S100PBP	281	Q96BU1
GALLAGMKHVKKEKA	SCO1	106	O75880
HGVVSVLTKGNKEMK	HCN2	586	Q9UL51
LKEKRKLFIHSMGEG	CARD16	6	Q5EG05
LHTKGKMHRDIKGAN	MAP4K5	131	Q9Y4K4
GSFALNLIHGKMKTK	MTBP	426	Q96DY7
FSAMKLGKNRSHKEE	OTOF	176	Q9HC10
GFTKEVMNKYKVHGK	PPEF2	251	O14830
TKSHKRGMKGDTVNV	ODF2	41	Q5BJF6
DMKGALSRVIHQKKT	OR1E1	296	P30953
THQEMIKGIKKCTSG	APIP	136	Q96GX9
KYIIKKIKNMAHGSP	MROH5	106	Q6ZUA9
GKLARVVGMSKKHFF	MROH2A	1496	A6NES4
VVGMSKKHFFKGEVK	MROH2A	1501	A6NES4
THIKMKKQPKGYGLR	MRPS5	301	P82675
EGKDKHRMNKHKIGN	STRN3	271	Q13033
SGHLHAKGKEEKMSK	CARS2	306	Q9HA77
PNIGYGSNKKTKHML	RPL32	56	P62910
RLYGVHRMKKEKIVG	SYT14	346	Q8NB59
MKHKLGTDTKLIQGL	CCT6B	196	Q92526
MKAKNITHPKAKGTG	SLFN14	676	P0C7P3
KHGKRIGVQGKNRME	RPGRIP1	1006	Q96KN7
MVAGKLIHSKKKGDG	SELENOW	51	P63302
MRAELEYGLKKKSHG	HKDC1	491	Q2TB90
HNKAIAFKRKGGSGM	ABCC6	266	O95255
ISHSKKLNKKKGGEM	IQGAP2	846	Q13576
TRAVLAKLADHGKKM	NT5DC3	281	Q86UY8
LNKKKIFKGHMVAGY	CDC40	496	O60508
GILARKMHQDADGKK	PSD4	781	Q8NDX1
DVIKKHRISGAKTQM	POLR3A	291	O14802
GVRGHFKVVDSRMKK	FTSJ3	816	Q8IY81
KKHVGLLRIKGRKMN	MRE11	281	P49959
SKTKMDLGGHVKRKH	ERRFI1	441	Q9UJM3
DVNKALRKVMGSKIH	OR5L2	296	Q8NGL0
KMGNRHKFTGKKVTE	SRP68	101	Q9UHB9
DKNGKGLRHFSMKVC	TFDP2	126	Q14188
MHRRGVGAGAIAKKK	SNF8	1	Q96H20
DGVMVLSATHRYKKK	PRKAB1	246	Q9Y478
VKHGIKKGDTVVIYM	ACSS3	161	Q9H6R3
GRHKTTGQVVAMKKI	CDK1	21	P06493
NGLHMSKDKRIKSGK	CDYL2	56	Q8N8U2
SVGHKETKAIKQMFG	ASCC3	106	Q8N3C0
LEKSIKMGKRNGLHL	NLN	166	Q9BYT8
KKAGALMRKFGSDHT	SHFL	26	Q9NUL5
YLKGRSGDKMIHEKN	TUFT1	81	Q9NNX1
KNGKGLRHFSMKVCE	TFDP1	111	Q14186
THLGKIICKEMKGSK	ZNF624	241	Q9P2J8
MKGHHVNITKKGLSR	UNC80	1241	Q8N2C7
FVVMKLLAGGHKKES	NAA35	691	Q5VZE5
EAHRKKSLEGMKKAR	PPAN	341	Q9NQ55
HGGKRVMECLKKALK	VPS35	691	Q96QK1
GKKHGLKMLERSFSA	ZBTB41	236	Q5SVQ8
THAEKAGKRGKDMVN	UNC93A	121	Q86WB7
LKGNLSRHMKVKHGV	ZNF710	586	Q8N1W2
KKLGGANKEMTHLQK	SMC1A	896	Q14683
EFIQKHGRGMEKSNK	SRPRA	216	P08240
MSHTEVKLKIPFGNK	TEX30	1	Q5JUR7
HLKAMKANDKGRNKG	TRAV9-1	66	A0A075B6T8
GFKMMDGKQHIVLKL	ZNF518A	446	Q6AHZ1
TARVLIGHISKKMNK	GTF3C4	726	Q9UKN8
NHIGMGVRYNAEKKK	YJU2B	61	P13994
HDTKSVKLKEAMGGL	PLCB2	826	Q00722
FVMKDLLHKGKSNTG	ZNF347	96	Q96SE7
AIHGMETLKGETKKL	ZNF346	106	Q9UL40
KFTLKGNLTRHMKVK	ZNF366	541	Q8N895
GALFTHKMVHKEKGA	ZFX	501	P17010
KGMLHAREKCVGSVK	ZNF613	531	Q6PF04
KKHPGMKVKAADFAQ	ZNF462	1491	Q96JM2
AGLELGKKMKSRVHA	SEMA3G	756	Q9NS98
KLDSKIHQGAKKGLM	TRIP4	561	Q15650
KAAEVALKHLKGGSM	TARBP2	86	Q15633
LDGESTMGHRKKKRK	TMEM169	31	Q96HH4
GKKKGQMVDIHVTLT	TMEM169	111	Q96HH4
VKMSGAAKHKAKHGV	SETBP1	1101	Q9Y6X0
ICGGKKSHIRTLMLK	TNNI3K	76	Q59H18
LKRGMKVHLTQHSGK	ZNF425	341	Q6IV72
AVGRKTIEGLKKHME	ZNF512	176	Q96ME7
GKGAAELEKMTLKCH	ZNF512	276	Q96ME7
SLGHQKIMKRGKKSY	ZNF329	161	Q86UD4
IEKKKSHQGRGTMFE	HIVEP1	946	P15822
ERHTKGIGQKLLQKM	TFIP11	146	Q9UBB9
KDILMKYDKGHRAGL	USP6	16	P35125
KSALLKHQIVHMGGK	ZNF248	336	Q8NDW4
ASRKKMEELKTGGEH	THOC1	281	Q96FV9
AGALFTHKMVHKEKG	ZFY	496	P08048
QHLKGRTDFIKGMKK	VWA5B1	301	Q5TIE3
VSLFMLSSGKKKHGR	TRAV41	66	A0A0B4J266
KGRPGQMAKEHKKTV	MYO5A	621	Q9Y4I1
DIKRAAGAGMISKKH	NMD3	326	Q96D46
HVLKASKMLSGREYK	NEBL	291	O76041