Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Increased fetal movement	NEXMIF GLRB	4.24e-06	2	11	2	HP:0010519
Domain	Myosin_N	MYH1 MYH4	3.53e-04	15	35	2	IPR004009
Domain	Myosin_N	MYH1 MYH4	3.53e-04	15	35	2	PF02736
Domain	Myosin_tail_1	MYH1 MYH4	5.12e-04	18	35	2	PF01576
Domain	Myosin_tail	MYH1 MYH4	5.12e-04	18	35	2	IPR002928
Domain	Myosin-like_IQ_dom	MYH1 MYH4	5.72e-04	19	35	2	IPR027401
Domain	-	MYH1 MYH4	5.72e-04	19	35	2	4.10.270.10
Domain	LisH	NOLC1 TCOF1	1.25e-03	28	35	2	IPR006594
Domain	LisH	NOLC1 TCOF1	1.25e-03	28	35	2	SM00667
Domain	LISH	NOLC1 TCOF1	1.25e-03	28	35	2	PS50896
Domain	FHA	MKI67 AFDN	1.25e-03	28	35	2	SM00240
Domain	FHA_DOMAIN	MKI67 AFDN	1.53e-03	31	35	2	PS50006
Domain	FHA	MKI67 AFDN	1.53e-03	31	35	2	PF00498
Domain	FHA_dom	MKI67 AFDN	2.07e-03	36	35	2	IPR000253
Domain	-	MKI67 AFDN	2.07e-03	36	35	2	2.60.200.20
Domain	MYOSIN_MOTOR	MYH1 MYH4	2.30e-03	38	35	2	PS51456
Domain	Myosin_head	MYH1 MYH4	2.30e-03	38	35	2	PF00063
Domain	Myosin_head_motor_dom	MYH1 MYH4	2.30e-03	38	35	2	IPR001609
Domain	MYSc	MYH1 MYH4	2.30e-03	38	35	2	SM00242
Domain	SMAD_FHA_domain	MKI67 AFDN	4.27e-03	52	35	2	IPR008984
Domain	ZnF_C2HC	FAM90A8 FAM90A10	4.76e-03	55	35	2	SM00343
Domain	Znf_CCHC	FAM90A8 FAM90A10	4.76e-03	55	35	2	IPR001878
Domain	Homeobox_CS	BARX2 BARX1 CRX	5.03e-03	186	35	3	IPR017970
Domain	HTH_motif	BARX2 BARX1	7.40e-03	69	35	2	IPR000047
Domain	IQ	MYH1 MYH4	7.82e-03	71	35	2	PF00612
Domain	Homeobox	BARX2 BARX1 CRX	9.46e-03	234	35	3	PF00046
Domain	HOMEOBOX_1	BARX2 BARX1 CRX	9.68e-03	236	35	3	PS00027
Domain	HOX	BARX2 BARX1 CRX	9.79e-03	237	35	3	SM00389
Domain	Homeobox_dom	BARX2 BARX1 CRX	1.00e-02	239	35	3	IPR001356
Domain	HOMEOBOX_2	BARX2 BARX1 CRX	1.00e-02	239	35	3	PS50071
Domain	IQ	MYH1 MYH4	1.01e-02	81	35	2	SM00015
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MKI67 NOLC1 EIF5B AFDN ZFR RPL14 TCOF1 WDR46	3.53e-07	653	37	8	22586326
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	MKI67 NOLC1 EIF5B ZFR RPL14 SPATS2 WDR46	6.85e-07	483	37	7	36912080
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	MKI67 NOLC1 EIF5B ZFR RPL14 TCOF1 YTHDF3	7.96e-07	494	37	7	26831064
Pubmed	Barx2, a new homeobox gene of the Bar class, is expressed in neural and craniofacial structures during development.	BARX2 BARX1	1.10e-06	2	37	2	9122247
Pubmed	Cloning, characterization, localization, and mutational screening of the human BARX1 gene.	BARX2 BARX1	1.10e-06	2	37	2	10995576
Pubmed	Growth and muscle defects in mice lacking adult myosin heavy chain genes.	MYH1 MYH4	1.10e-06	2	37	2	9382868
Pubmed	Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.	MYH1 MYH4	1.10e-06	2	37	2	11150240
Pubmed	Skeletal muscle adaptations in response to voluntary wheel running in myosin heavy chain null mice.	MYH1 MYH4	1.10e-06	2	37	2	11744674
Pubmed	Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling.	MKI67 BARX2 BARX1	1.25e-06	20	37	3	21750040
Pubmed	Function of atypical protein kinase C lambda in differentiating photoreceptors is required for proper lamination of mouse retina.	MKI67 AFDN CRX	1.93e-06	23	37	3	16267237
Pubmed	Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.	MYH1 MYH4	3.30e-06	3	37	2	26059207
Pubmed	Simultaneous loss of skeletal muscle myosin heavy chain IIx and IIb causes severe skeletal muscle hypoplasia in postnatal mice.	MYH1 MYH4	3.30e-06	3	37	2	36515178
Pubmed	Phosphorylation of proteins by inositol pyrophosphates.	NOLC1 TCOF1	3.30e-06	3	37	2	15604408
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	MKI67 TMEM214 SPATS2 TCOF1 YTHDF3 WDR46	4.42e-06	410	37	6	26949251
Pubmed	Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism.	MKI67 MYH1 MYH4	4.88e-06	31	37	3	30081710
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	MKI67 NOLC1 EIF5B ZFR RPL14 SPATS2 TCOF1	5.13e-06	655	37	7	35819319
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	MKI67 NOLC1 EIF5B ZFR RPL14 RNF168 TCOF1 WDR46	5.71e-06	949	37	8	36574265
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	MKI67 NOLC1 ATXN7L3 ZFR TMEM214 RPL14 RNF168 KAT5 TCOF1	6.45e-06	1294	37	9	30804502
Pubmed	Molecular mechanism of synovial joint site specification and induction in developing vertebrate limbs.	BARX2 BARX1	6.60e-06	4	37	2	37272420
Pubmed	Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.	MYH1 MYH4	6.60e-06	4	37	2	10388558
Pubmed	A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.	MYH1 MYH4	6.60e-06	4	37	2	11023856
Pubmed	Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.	MYH1 MYH4	6.60e-06	4	37	2	1985022
Pubmed	Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.	MYH1 MYH4	6.60e-06	4	37	2	11029314
Pubmed	Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.	MYH1 MYH4	6.60e-06	4	37	2	18417546
Pubmed	Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.	MYH1 MYH4	6.60e-06	4	37	2	12547197
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	MKI67 NOLC1 EIF5B ZFR RPL14 TCOF1	6.70e-06	441	37	6	31239290
Pubmed	Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.	MKI67 NOLC1 ZFR RPL14 TCOF1	8.05e-06	260	37	5	36199071
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MKI67 NOLC1 EIF5B AFDN ZFR RPL14 TCOF1 WDR46	9.93e-06	1024	37	8	24711643
Pubmed	Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.	MYH1 MYH4	1.10e-05	5	37	2	30737693
Pubmed	Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.	MYH1 MYH4	1.10e-05	5	37	2	6196357
Pubmed	Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.	MYH1 MYH4	1.10e-05	5	37	2	3829126
Pubmed	Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.	MYH1 MYH4	1.10e-05	5	37	2	12919077
Pubmed	Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.	MYH1 MYH4	1.65e-05	6	37	2	1728586
Pubmed	A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity.	MYH1 MYH4	1.65e-05	6	37	2	20417199
Pubmed	Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.	MYH1 MYH4	1.65e-05	6	37	2	10077619
Pubmed	A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre.	MYH1 MYH4	1.65e-05	6	37	2	17559643
Pubmed	Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.	MYH1 MYH4	1.65e-05	6	37	2	10588881
Pubmed	Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration.	BARX2 BARX1	1.65e-05	6	37	2	23532528
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	MKI67 NOLC1 ZFR TCOF1	1.86e-05	148	37	4	32538781
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	NOLC1 EIF5B ZFR RPL14 TCOF1 YTHDF3 WDR46	1.98e-05	807	37	7	22681889
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	NOLC1 MYH1 AFDN RPL14 TCOF1	2.09e-05	317	37	5	17620599
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	NOLC1 EIF5B RPL14 TCOF1 YTHDF3	2.09e-05	317	37	5	30997501
Pubmed	Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting.	MYH1 AFDN MYH4 RPL14	2.23e-05	155	37	4	22673621
Pubmed	A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.	MYH1 MYH4	2.30e-05	7	37	2	35210422
Pubmed	ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.	MYH1 MYH4	2.30e-05	7	37	2	29758057
Pubmed	Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.	MYH1 MYH4	2.30e-05	7	37	2	16819597
Pubmed	The homeodomain protein Barx2 contains activator and repressor domains and interacts with members of the CREB family.	BARX2 BARX1	2.30e-05	7	37	2	10781615
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	MKI67 NOLC1 EIF5B TCOF1 WDR46	2.96e-05	341	37	5	32971831
Pubmed	Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.	MYH1 MYH4	3.07e-05	8	37	2	26993635
Pubmed	Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.	MYH1 MYH4	3.07e-05	8	37	2	3864153
Pubmed	Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex.	MYH1 MYH4	3.07e-05	8	37	2	36200826
Pubmed	Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development.	MYH1 MYH4	3.07e-05	8	37	2	33667029
Pubmed	A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning.	MYH1 MYH4	3.07e-05	8	37	2	14667415
Pubmed	A cellular and spatial map of the choroid plexus across brain ventricles and ages.	MKI67 PRLR CRX	3.46e-05	59	37	3	33932339
Pubmed	GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.	MYH1 MYH4	3.95e-05	9	37	2	31960486
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	MKI67 NOLC1 ZFR RPL14 SPATS2 TCOF1	3.97e-05	605	37	6	28977666
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MKI67 NOLC1 EIF5B AFF1 RPL14 SPATS2 TCOF1 YTHDF3	4.08e-05	1247	37	8	27684187
Pubmed	During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation.	MYH1 MYH4	4.93e-05	10	37	2	19506036
Pubmed	PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways.	MKI67 TCOF1	4.93e-05	10	37	2	24788519
Pubmed	Extracellular matrix protein composition dynamically changes during murine forelimb development.	MYH1 MYH4	6.02e-05	11	37	2	38303699
Pubmed	Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.	MYH1 MYH4	6.02e-05	11	37	2	18310078
Pubmed	Developmental stalling and organ-autonomous regulation of morphogenesis.	BARX2 BARX1	6.02e-05	11	37	2	22084104
Pubmed	The histone code reader Spin1 controls skeletal muscle development.	MYH1 MYH4	6.02e-05	11	37	2	29168801
Pubmed	Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.	MYH1 MYH4	6.02e-05	11	37	2	8136524
Pubmed	Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood.	MKI67 BARX1	6.02e-05	11	37	2	19429790
Pubmed	Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.	MYH1 MYH4	6.02e-05	11	37	2	16024798
Pubmed	Proteomic analysis of human Nop56p-associated pre-ribosomal ribonucleoprotein complexes. Possible link between Nop56p and the nucleolar protein treacle responsible for Treacher Collins syndrome.	NOLC1 RPL14 TCOF1	6.28e-05	72	37	3	12777385
Pubmed	Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye.	MKI67 CRX	7.22e-05	12	37	2	18582859
Pubmed	KLF4 regulates skeletal muscle development and regeneration by directly targeting P57 and Myomixer.	MKI67 MYH1	7.22e-05	12	37	2	37723138
Pubmed	Cdx2 regulates patterning of the intestinal epithelium.	MKI67 BARX1	7.22e-05	12	37	2	20043902
Pubmed	IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade.	MKI67 AFDN	7.22e-05	12	37	2	18604197
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	ZFR RPL14 RNF168 KAT5 HECA	7.69e-05	417	37	5	36537216
Pubmed	TAF7L modulates brown adipose tissue formation.	MYH1 MYH4	8.53e-05	13	37	2	24876128
Pubmed	Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.	MYH1 MYH4	8.53e-05	13	37	2	8404542
Pubmed	Sonic hedgehog is essential for first pharyngeal arch development.	MKI67 BARX1	8.53e-05	13	37	2	16492970
Pubmed	Loss of Prox1 in striated muscle causes slow to fast skeletal muscle fiber conversion and dilated cardiomyopathy.	MYH1 MYH4	9.94e-05	14	37	2	24938781
Pubmed	Cell-fate determination by ubiquitin-dependent regulation of translation.	NOLC1 TCOF1	9.94e-05	14	37	2	26399832
Pubmed	The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3.	MKI67 PRLR	9.94e-05	14	37	2	22588720
Pubmed	Astrocyte-intrinsic and -extrinsic Fat1 activities regulate astrocyte development and angiogenesis in the retina.	MKI67 MYH1	9.94e-05	14	37	2	35050341
Pubmed	Defective excitation-contraction coupling is partially responsible for impaired contractility in hindlimb muscles of Stac3 knockout mice.	MYH1 MYH4	9.94e-05	14	37	2	27184118
Pubmed	Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation.	MYH1 MYH4	9.94e-05	14	37	2	33742095
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MKI67 NOLC1 EIF5B AFDN ZFR RPL14 TCOF1 WDR46	1.04e-04	1425	37	8	30948266
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	NOLC1 EIF5B RPL14 SPATS2 KAT5 YTHDF3	1.06e-04	723	37	6	34133714
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	MKI67 EIF5B ZFR SPATS2 YTHDF3 WDR46	1.07e-04	724	37	6	36232890
Pubmed	Multisite dependency of an E3 ligase controls monoubiquitylation-dependent cell fate decisions.	NOLC1 TCOF1	1.15e-04	15	37	2	29999490
Pubmed	Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate.	MKI67 MYH1	1.15e-04	15	37	2	31618630
Pubmed	Six homeoproteins and a Iinc-RNA at the fast MYH locus lock fast myofiber terminal phenotype.	MYH1 MYH4	1.15e-04	15	37	2	24852826
Pubmed	Impairment of radial glial scaffold-dependent neuronal migration and formation of double cortex by genetic ablation of afadin.	MKI67 AFDN	1.15e-04	15	37	2	25988834
Pubmed	Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon.	MKI67 AFDN	1.15e-04	15	37	2	25100583
Pubmed	Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice.	MKI67 MYH1	1.15e-04	15	37	2	31420575
Pubmed	MusTRD can regulate postnatal fiber-specific expression.	MYH1 MYH4	1.31e-04	16	37	2	16494860
Pubmed	A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.	MYH1 MYH4	1.31e-04	16	37	2	19922871
Pubmed	Molecular signaling at the fusion stage of the mouse mandibular arch: involvement of insulin-like growth factor family.	MKI67 BARX1	1.31e-04	16	37	2	23584732
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	MKI67 EIF5B RPL14 RNF168	1.43e-04	250	37	4	33536335
Pubmed	LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.	MKI67 EIF5B	1.48e-04	17	37	2	37072811
Pubmed	IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.	MYH1 MYH4	1.48e-04	17	37	2	22351927
Pubmed	Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect.	MKI67 BARX1	1.48e-04	17	37	2	24785830
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MKI67 NOLC1 EIF5B AFF1 AFDN TCOF1	1.54e-04	774	37	6	15302935
Pubmed	Neuron-specific antioxidant OXR1 extends survival of a mouse model of amyotrophic lateral sclerosis.	MYH1 MYH4	1.67e-04	18	37	2	25753484
Pubmed	RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.	MKI67 RNF168	1.67e-04	18	37	2	27558965
Interaction	MEN1 interactions	MKI67 NOLC1 EIF5B AFDN ZFR RPL14 SPATS2 TCOF1 YTHDF3 WDR46	6.57e-06	1029	35	10	int:MEN1
Interaction	SIRT7 interactions	MKI67 NOLC1 EIF5B AFDN ZFR RPL14 TCOF1 WDR46	3.23e-05	744	35	8	int:SIRT7
Interaction	ASAH2 interactions	MYH1 MYH4	4.38e-05	6	35	2	int:ASAH2
Interaction	USP36 interactions	MKI67 NOLC1 EIF5B ZFR RPL14 SPATS2 WDR46	6.45e-05	599	35	7	int:USP36
Interaction	FBL interactions	MKI67 NOLC1 EIF5B ZFR TCOF1 YTHDF3 WDR46	9.67e-05	639	35	7	int:FBL
Interaction	MKI67 interactions	MKI67 TMEM214 SPATS2 RNF168 TCOF1 YTHDF3 WDR46	1.06e-04	648	35	7	int:MKI67
Interaction	NSD2 interactions	MKI67 RPL14 KAT5 TCOF1 WDR46	1.11e-04	278	35	5	int:NSD2
Interaction	DPM2 interactions	TMEM214 GLRB WDR46	1.12e-04	54	35	3	int:DPM2
Interaction	ARL4D interactions	MKI67 NOLC1 ZFR TCOF1	1.16e-04	146	35	4	int:ARL4D
Interaction	OBSL1 interactions	MKI67 NOLC1 EIF5B AFDN ZFR RPL14 TCOF1 WDR46	1.25e-04	902	35	8	int:OBSL1
Interaction	RNF113A interactions	MKI67 NOLC1 EIF5B ZFR RPL14 SPATS2 TCOF1	1.59e-04	692	35	7	int:RNF113A
Interaction	RIOX1 interactions	MKI67 RPL14 KAT5	1.61e-04	61	35	3	int:RIOX1
Interaction	HECA interactions	HECA YTHDF3	1.91e-04	12	35	2	int:HECA
Interaction	EPC2 interactions	MKI67 KAT5 CRX	2.13e-04	67	35	3	int:EPC2
Interaction	BRCA1 interactions	MKI67 NOLC1 EIF5B ZFR RPL14 RNF168 KAT5 TCOF1 YTHDF3	2.13e-04	1249	35	9	int:BRCA1
Interaction	TMEM260 interactions	MYH1 MYH4	2.26e-04	13	35	2	int:TMEM260
Interaction	SMC5 interactions	MKI67 NOLC1 EIF5B MYH1 AFDN MYH4 ZFR YTHDF3	2.54e-04	1000	35	8	int:SMC5
Interaction	BARX1 interactions	RPL14 BARX1	2.63e-04	14	35	2	int:BARX1
Interaction	UBR5 interactions	NOLC1 EIF5B MYH4 RPL14 RNF168 CSPP1	2.81e-04	533	35	6	int:UBR5
Interaction	BTRC interactions	MKI67 NOLC1 ZFR RPL14 TCOF1 PRLR YTHDF3	3.17e-04	775	35	7	int:BTRC
Interaction	LINC00240 interactions	MKI67 EIF5B	3.46e-04	16	35	2	int:LINC00240
Interaction	ZNF526 interactions	AFF1 RPL14 KAT5	3.60e-04	80	35	3	int:ZNF526
Cytoband	8p23.1	PRAG1 FAM90A8 FAM90A10	2.65e-04	154	37	3	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3p26	GRM7 SUMF1	7.26e-04	49	37	2	chr3p26
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	PRAG1 FAM90A8 FAM90A10	8.94e-04	234	37	3	chr8p23
Cytoband	19q13.3	CRX SIGLEC10	2.02e-03	82	37	2	19q13.3
Cytoband	17p13.1	MYH1 MYH4	4.11e-03	118	37	2	17p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr5p13	ZFR PRLR	5.65e-03	139	37	2	chr5p13
GeneFamily	Myosin heavy chains	MYH1 MYH4	1.34e-04	15	21	2	1098
GeneFamily	NKL subclass homeoboxes and pseudogenes	BARX2 BARX1	2.71e-03	67	21	2	519
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MKI67 GRM7	1.85e-02	181	21	2	694
Coexpression	HUMMERICH_BENIGN_SKIN_TUMOR_DN	AFF1 MYH1 MYH4	2.67e-06	20	36	3	M1123
Coexpression	HUMMERICH_BENIGN_SKIN_TUMOR_DN	AFF1 MYH1 MYH4	3.11e-06	21	36	3	MM1102
Disease	Treacher Collins syndrome (implicated_via_orthology)	NOLC1 TCOF1	1.93e-05	6	34	2	DOID:2908 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:0110454 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:0111602 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:3429 (implicated_via_orthology)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:0111269 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:0080719 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:0080326 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH1 MYH4	5.77e-05	10	34	2	DOID:0111596 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH1 MYH4	8.44e-05	12	34	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH1 MYH4	8.44e-05	12	34	2	DOID:2106 (implicated_via_orthology)
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH1 MYH4	9.97e-05	13	34	2	DOID:397 (implicated_via_orthology)
Disease	distal arthrogryposis (implicated_via_orthology)	MYH1 MYH4	1.34e-04	15	34	2	DOID:0050646 (implicated_via_orthology)
Disease	triglyceride measurement, phospholipid measurement	AFF1 NR1H3 KAT5	6.35e-04	146	34	3	EFO_0004530, EFO_0004639
Disease	serum non-albumin protein measurement	TBC1D16 AFF1 AFDN RNF168	7.65e-04	361	34	4	EFO_0004568
Disease	myopathy (implicated_via_orthology)	MYH1 MYH4	1.41e-03	48	34	2	DOID:423 (implicated_via_orthology)
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	AFF1 NR1H3 KAT5	1.57e-03	200	34	3	EFO_0004611, EFO_0020945
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	AFF1 NR1H3 KAT5	1.71e-03	206	34	3	EFO_0004612, EFO_0020947
Disease	triglycerides to total lipids in medium HDL percentage	AFF1 NR1H3	1.91e-03	56	34	2	EFO_0022333
Disease	mean reticulocyte volume	TBC1D16 AFF1 AFDN RNF168 NEXMIF	2.09e-03	799	34	5	EFO_0010701
Disease	triglycerides to total lipids in small LDL percentage	AFF1 KAT5	2.12e-03	59	34	2	EFO_0022337
Disease	basophil measurement	AFF1 HECA	2.19e-03	60	34	2	EFO_0803539
Disease	dehydroepiandrosterone sulphate measurement	PRLR CRX	2.80e-03	68	34	2	EFO_0007001
Disease	cardiomyopathy (implicated_via_orthology)	MYH1 MYH4	3.05e-03	71	34	2	DOID:0050700 (implicated_via_orthology)
Disease	psychotic symptoms	PRLR SUMF1	3.30e-03	74	34	2	EFO_0005940
Disease	response to alcohol	AFDN SHF	3.39e-03	75	34	2	EFO_0005526
Disease	triglyceride measurement, high density lipoprotein cholesterol measurement	AFF1 NR1H3 KAT5	3.83e-03	274	34	3	EFO_0004530, EFO_0004612
Disease	dilated cardiomyopathy (implicated_via_orthology)	MYH1 MYH4	3.85e-03	80	34	2	DOID:12930 (implicated_via_orthology)
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	AFF1 NR1H3 KAT5	4.53e-03	291	34	3	EFO_0008317, EFO_0020946
Disease	childhood aggressive behaviour measurement	BARX2 ARHGAP40	4.74e-03	89	34	2	EFO_0007663

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPKKAQSNGPEKQEK	AFDN	136	P55196
KPRGEANPGPLNKDK	FAM90A10	86	A6NDY2
ASGLGSNKKKKPKPP	ATXN7L3	321	Q14CW9
EKLKGKGSPRPQAPK	NOLC1	531	Q14978
PQKRKKGPAPKMLGN	NR1H3	81	Q13133
EAKKCRPPNKPQKGP	HECA	221	Q9UBI9
PKKEAKTPTKNGLPG	KAT5	71	Q92993
GLESPTKPKGRPKKN	BARX1	206	Q9HBU1
PKSQRNKKPIGQVKP	CSPP1	206	Q1MSJ5
NGLGKSQAKNNKKPP	GLRB	446	P48167
GKSNNFQKPKPAKGK	MYH1	561	P12882
GSKRQPRTPKGKAQP	MKI67	2176	P46013
KPRGEANPGPLNKDK	FAM90A8	86	A6NJQ4
GQEAPTKPKGRPKKN	BARX2	196	Q9UMQ3
PCKPGQRKKTQKGTP	GRM7	526	Q14831
QPPGGQAKARPAKRK	CRX	106	O43186
KPRGEANPGPLNKDK	FAM90A24P	86	P0C7X0
PQKSRKPKKGAGNPQ	TCOF1	1271	Q13428
LKGNNKGIEKPPGKN	NEXMIF	1201	Q5QGS0
KGIEKPPGKNSRQVP	NEXMIF	1206	Q5QGS0
SRKGQKKNQKNKPGP	EIF5B	196	O60841
KKNQKNKPGPNIESG	EIF5B	201	O60841
KPRGEANPGPLNKDK	FAM90A13P	86	P0C7W8
GKSNNFQKPKPAKGK	MYH4	561	Q9Y623
LNPKGPPSGKDRVKK	SUMF1	316	Q8NBK3
PNGNSKPGKPQVKFD	AFF1	946	P51825
SPQPVANGPKQKKKS	SHF	66	Q7M4L6
KKKNKPKPAAEPSNG	SPATS2	91	Q86XZ4
AKPQPKLKPKGNVGI	YTHDF3	246	Q7Z739
QGRPPKLPKGKEKQL	ARHGAP40	436	Q5TG30
KGQKAPAQKAPAPKA	RPL14	196	P50914
NGKKPGSFPKQLRPN	SPATA31D1	431	Q6ZQQ2
PKSLREGKKGPKTPQ	TBC1D16	746	Q8TBP0
PGNKKQPKKVATPPN	TMEM214	86	Q6NUQ4
KQRENSGKPKKPGTP	PRLR	526	P16471
SGKPKKPGTPENNKE	PRLR	531	P16471
GKPEAPKGSPQINRK	TMCC1	126	O94876
KQKPGGTPNLQQKKS	PRAG1	1221	Q86YV5
AKAPFQPKPKQKGRS	WDR46	546	O15213
SPPDKVLNGQRKNPK	RNF168	481	Q8IYW5
KAPFQNKQLKPKQPP	ZFR	311	Q96KR1
PGAPSPESKKNQKKQ	SIGLEC10	626	Q96LC7