Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR2W1 ADGRG7 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	3.34e-09	884	44	14	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	2.55e-08	431	44	10	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR2W1 SOSTDC1 ADGRG7 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	9.54e-08	1353	44	15	GO:0004888
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.92e-08	432	44	10	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	3.85e-08	465	44	10	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	5.71e-08	485	44	10	GO:0050907
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.17e-07	524	44	10	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.75e-07	547	44	10	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	3.10e-07	582	44	10	GO:0050906
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR2W1 ADGRG7 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	6.58e-07	1395	44	14	GO:0007186
GeneOntologyBiologicalProcess	sensory perception	OR2W1 COL18A1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 MYO5A OR51M1 OR13J1 OR52H1 OR8K5	1.64e-06	1072	44	12	GO:0007600
GeneOntologyBiologicalProcess	detection of stimulus	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	2.19e-06	722	44	10	GO:0051606
GeneOntologyBiologicalProcess	cellular response to caffeine	CACNA1S RYR3	2.42e-04	11	44	2	GO:0071313
GeneOntologyBiologicalProcess	cellular response to purine-containing compound	CACNA1S RYR3	3.98e-04	14	44	2	GO:0071415
Domain	GPCR_Rhodpsn_7TM	OR2W1 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	2.70e-09	670	44	13	IPR017452
Domain	7tm_1	OR2W1 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	3.06e-09	677	44	13	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR2W1 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	3.53e-09	685	44	13	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2W1 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	3.92e-09	691	44	13	PS50262
Domain	GPCR_Rhodpsn	OR2W1 OR52R1 TAAR1 OR5M10 OR5M1 OR52K2 OR6S1 P2RY11 OR51M1 OR13J1 OR52H1 OR8K5 MC2R	3.99e-09	692	44	13	IPR000276
Domain	Olfact_rcpt	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.99e-08	393	44	10	IPR000725
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	2.26e-08	389	35	10	M14091
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	4.36e-08	417	35	10	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 AWAT2 OR52H1 OR8K5	2.24e-07	636	35	11	M41834
Pathway	KEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY	CACNA1S RYR3	3.25e-04	11	35	2	M47958
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.65e-11	340	45	10	11875048
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.79e-11	343	45	10	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.95e-11	346	45	10	14611657
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR51M1 OR13J1 OR52H1 OR8K5	4.77e-10	340	45	9	11802173
Pubmed	The human olfactory receptor gene family.	OR2W1 OR52R1 OR5M10 OR5M1 OR52K2 OR6S1 OR51M1 OR13J1 OR52H1 OR8K5	1.50e-09	541	45	10	14983052
Pubmed	Myosin Va and Endoplasmic Reticulum Calcium Channel Complex Regulates Membrane Export during Axon Guidance.	MYO5A RYR3	1.64e-06	2	45	2	27134178
Pubmed	Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.	CACNA1S RYR3	2.45e-05	6	45	2	10444070
Pubmed	Protein microarray characterization of the S-nitrosoproteome.	UBE3A RNF11	4.56e-05	8	45	2	24105792
Pubmed	Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy.	CACNA1S RYR3	5.86e-05	9	45	2	21858002
Pubmed	Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.	TAAR1 P2RY11 MC2R	1.04e-04	70	45	3	12036966
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR2W1 OR6S1 OR8K5	1.23e-04	74	45	3	15081110
Pubmed	Dissection of behavior and psychiatric disorders using the mouse as a model.	UBE3A RYR3	7.43e-04	31	45	2	10767319
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	CACNA1S SLC13A2 RYR3	8.51e-04	143	45	3	20424473
Cytoband	11p15.4	OR52R1 OR52K2 OR51M1 OR52H1	4.53e-05	200	45	4	11p15.4
Cytoband	11q12.1	OR5M10 OR5M1 OR8K5	5.39e-04	161	45	3	11q12.1
GeneFamily	Olfactory receptors, family 52	OR52R1 OR52K2 OR52H1	1.25e-04	49	36	3	165
GeneFamily	SH2 domain containing	TNS2 SOCS3	1.72e-02	101	36	2	741
GeneFamily	Olfactory receptors, family 5	OR5M10 OR5M1	2.09e-02	112	36	2	152
Disease	childhood trauma measurement, smoking behaviour measurement	COL18A1 RIC1	1.54e-03	45	38	2	EFO_0005671, EFO_0007979
Disease	abdominal adipose tissue measurement	CACNA1S SOCS3	2.14e-03	53	38	2	EFO_0803316

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCLALPVYPALVIMH	CYB561D1	201	Q8N8Q1
FLLYVALAHMHVPLP	ARSG	241	Q96EG1
IPNPMCTAIAALLHY	ADGRG7	521	Q96K78
HFYCADPPLIMLACS	OR5M10	176	Q6IEU7
LSALQLLVYLMPPCH	ARHGAP36	326	Q6ZRI8
CATLPYFPHVLELML	RIC1	851	Q4ADV7
TDLCLLYPPFMIALA	CCNC	186	P24863
LYPPFMIALACLHVA	CCNC	191	P24863
HFYCDDVPLLPMLCS	OR8K5	176	Q8NH50
PLAFCVHPLLYMAAV	P2RY11	311	Q96G91
VHPLLYMAAVPSLGC	P2RY11	316	Q96G91
ICKPLHYFVVMNPHL	OR2W1	126	Q9Y3N9
PPAIHLLMANVYLFV	OR51M1	281	Q9H341
MAPYPCGCHILLLLF	COL18A1	1	P39060
NIDVLFPHMPCAYLS	ERGIC3	71	Q9Y282
PQCLSLLHAMVAYDP	MOK	256	Q9UQ07
LAPAHCYLPNLKVML	PRSS37	51	A4D1T9
PALEHLLFPLCSAMY	OR13J1	21	Q8NGT2
MTPLCPRPALCYHFL	DUT	1	P33316
HILFANLYLLIPPML	OR52R1	276	Q8NGF1
LAICHPLRYPLLMSG	OR6S1	126	Q8NH40
CTLILPMYHLEPFFS	CERS3	286	Q8IU89
MALQHGVPLIPAYAF	AWAT2	211	Q6E213
IFANCVALAVYLPMP	CACNA1S	61	Q13698
PRLYAPLISFHCMCF	LINC00473	131	A8K010
PHLLDYCCAPMPYLI	DENND1B	251	Q6P3S1
AQAICLHPLYVMLPC	SLC13A2	491	Q13183
HIMFANLYIVIPPAL	OR52H1	281	Q8NGJ2
TLMTPLPFLLRCFHY	OR52K2	156	Q8NGK3
FVYGDPIRFLPCMHI	RNF11	106	Q9Y3C5
PIRFLPCMHIYHLDC	RNF11	111	Q9Y3C5
HFYCADPPLIMLACS	OR5M1	176	Q8NGP8
LNILYLHMPDCPVSL	FAM178B	311	Q8IXR5
VLHVLLMTFCPSNPY	MC2R	236	Q01718
LHSPEYLEMALPLFC	UBE3A	296	Q05086
AVVACFRMAPLYNLP	RYR3	3486	Q15413
LRKAMAPVHLPLSCY	HEATR9	31	A2RTY3
IFAHCIPPSCNYMIL	THNSL1	361	Q8IYQ7
RFDCVLKLVHHYMPP	SOCS3	116	O14543
PFFICTVMDPFLHYI	TAAR1	266	Q96RJ0
MLPPAIHFYLLPLAC	SOSTDC1	1	Q6X4U4
PIPALLFNCTMALIY	SLC7A6	366	Q92536
FILCVYPSGMPALRH	SLC29A4	431	Q7RTT9
VRLYDFFLACHPLMP	TBC1D20	236	Q96BZ9
FFLACHPLMPIYFAA	TBC1D20	241	Q96BZ9
PLFLHYVLIPMLPAF	TNS2	301	Q63HR2
PMHTCARYLFTALLP	ZSWIM4	541	Q9H7M6
AMLHPEVCEPLYVLA	GEMIN4	991	P57678
PGLPAYILFMCVRHA	MYO5A	1506	Q9Y4I1