Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-0941194GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-0941194GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-0941194GO:0047743
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0951194GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0951194GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0951194GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0951194GO:0047006
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0951194GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0951194GO:0047086
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0951194GO:0047787
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.78e-0861194GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.14e-0871194GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.24e-0881194GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.24e-0881194GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.24e-0881194GO:0035671
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.48e-0791194GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.48e-0791194GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.45e-07101194GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.45e-07101194GO:0032052
GeneOntologyMolecularFunctionNADPH binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3 KDSR

4.11e-07261195GO:0070402
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.15e-06141194GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.15e-06141194GO:0001758
GeneOntologyMolecularFunctionNADP binding

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3 KDSR

1.85e-06621196GO:0050661
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRT PTPRF PTPRG PTPRZ1

2.69e-06171194GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRT PTPRF PTPRG PTPRZ1

2.69e-06171194GO:0019198
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.40e-06201194GO:0004303
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.16e-05241194GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.62e-05261194GO:0004022
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.89e-05271194GO:0008106
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.92e-05301194GO:0018455
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C3

3.29e-05111193GO:0030283
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.79e-05321194GO:0004033
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.29e-05331194GO:0033764
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.84e-05341194GO:0016628
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.39e-05391194GO:0016229
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.28e-05401194GO:0016709
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.91e-04481194GO:0016620
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

2.10e-0441192GO:0047718
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.47e-04561194GO:0016903
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.52e-04601194GO:0016655
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.12e-04621194GO:0016627
GeneOntologyMolecularFunctionrRNA (cytosine) methyltransferase activity

NSUN4 METTL15P1

5.20e-0461192GO:0016434
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3 KDSR

9.85e-041271195GO:0016616
GeneOntologyMolecularFunctionATP-dependent activity

ABCA4 ERCC6L ABCA12 MYO10 MCM2 NLRP1 MCM6 IDE DDX5 KIF9 HELLS

1.11e-0361411911GO:0140657
GeneOntologyMolecularFunctiontestosterone dehydrogenase (NAD+) activity

AKR1C4 AKR1C3

1.23e-0391192GO:0047035
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA4 ERCC6L ABCA12 MCM2 NLRP1 MCM6 IDE DDX5 KIF9

1.31e-034411199GO:0016887
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

AKR1C4 AKR1C1 AKR1C2 AKR1C3 KDSR

1.43e-031381195GO:0016614
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.51e-03951194GO:0016651
GeneOntologyMolecularFunctionhelicase activity

ERCC6L MCM2 MCM6 DDX5 HELLS

2.58e-031581195GO:0004386
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

PTPRT PTPRF PTPRG PTPRZ1

3.37e-031031194GO:0004725
GeneOntologyMolecularFunctionmonocarboxylic acid binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.86e-031071194GO:0033293
GeneOntologyMolecularFunction3'-5' DNA helicase activity

MCM2 MCM6

4.00e-03161192GO:0043138
GeneOntologyMolecularFunctionmonooxygenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.99e-031151194GO:0004497
GeneOntologyMolecularFunctionmolecular sequestering activity

USP9X YWHAZ SEC14L1

5.26e-03591193GO:0140313
GeneOntologyMolecularFunctionextracellular matrix structural constituent

NID2 COL6A5 HMCN1 NID1 DMBT1

5.40e-031881195GO:0005201
GeneOntologyMolecularFunctionendopeptidase activator activity

NLRP1 PSME2

5.64e-03191192GO:0061133
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA4 ERCC6L ABCA12 MCM2 NLRP1 MCM6 IDE DDX5 RGS14 GUF1 KIF9

6.61e-0377511911GO:0017111
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.02e-0941184GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.02e-0941184GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.02e-0941184GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.02e-0941184GO:0008208
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.07e-0951184GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.07e-0951184GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.07e-0951184GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.07e-0951184GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.07e-0951184GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.07e-0951184GO:1900053
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.51e-0861184GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.51e-0861184GO:0016095
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.52e-0871184GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.52e-0871184GO:0071799
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.52e-0871184GO:1900052
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C4 IDE AKR1C1 AKR1C2 AKR1C3

1.06e-07211185GO:0042447
GeneOntologyBiologicalProcessretinal metabolic process

ABCA4 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.06e-07211185GO:0042574
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.25e-0791184GO:0044597
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.08e-07101184GO:0044598
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.08e-07101184GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.08e-07101184GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.08e-07101184GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.08e-07101184GO:0030647
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.26e-07111184GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.26e-07111184GO:0016115
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.75e-07141184GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.75e-07141184GO:0008300
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.32e-06151184GO:0016102
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.76e-06161184GO:0061370
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.76e-06161184GO:0032351
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.93e-06181184GO:0030656
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.65e-06211184GO:0016114
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.65e-06211184GO:0048385
GeneOntologyBiologicalProcessketone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.65e-06211184GO:0042182
GeneOntologyBiologicalProcessparturition

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.88e-06221184GO:0007567
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.88e-06221184GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.88e-06221184GO:0042448
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.88e-06221184GO:1902644
GeneOntologyBiologicalProcessneuron development

EPHB2 CUL4B CACNA1F TMEM67 FAT4 NCKAP1 HTRA2 PLEKHG4 USP9X SYNE1 SPAG6 TENM2 YWHAZ SEMA3A PTK2B BMP7 SRGAP2C PTPRF PTPRG WASHC5 PTPRZ1 PCDH15 ULK2

7.89e-06146311823GO:0048666
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.29e-06231184GO:0071379
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.29e-06231184GO:0034310
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.38e-05261184GO:0010566
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.87e-05281184GO:0048025
GeneOntologyBiologicalProcesspolyprenol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.16e-05291184GO:0016093
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.16e-05291184GO:0050686
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

EPHB2 TMEM67 NCKAP1 MYO10 SYNE1 SDCCAG8 TENM2 SEMA3A PTK2B BMP7 SRGAP2C PTPRF PTPRG WASHC5 PTPRZ1 ULK2

2.59e-0584611816GO:0120035
GeneOntologyBiologicalProcessterpenoid metabolic process

ABCA4 HTRA2 AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.13e-051051186GO:0006721
GeneOntologyBiologicalProcesspositive regulation of endothelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.23e-05321184GO:2000353
GeneOntologyBiologicalProcessregulation of cell projection organization

EPHB2 TMEM67 NCKAP1 MYO10 SYNE1 SDCCAG8 TENM2 SEMA3A PTK2B BMP7 SRGAP2C PTPRF PTPRG WASHC5 PTPRZ1 ULK2

3.29e-0586311816GO:0031344
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.66e-05331184GO:0033119
GeneOntologyBiologicalProcessneuron projection development

EPHB2 CUL4B CACNA1F FAT4 NCKAP1 PLEKHG4 USP9X SYNE1 SPAG6 TENM2 SEMA3A PTK2B BMP7 SRGAP2C PTPRF PTPRG WASHC5 PTPRZ1 PCDH15 ULK2

3.90e-05128511820GO:0031175
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.13e-05341184GO:0006706
GeneOntologyBiologicalProcessolefinic compound biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.65e-05351184GO:0120255
GeneOntologyBiologicalProcessresponse to fatty acid

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.72e-05691185GO:0070542
GeneOntologyBiologicalProcessresponse to prostaglandin

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.20e-05361184GO:0034694
GeneOntologyBiologicalProcessisoprenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.20e-05361184GO:0008299
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.46e-05381184GO:0048384
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.93e-05401184GO:0042573
GeneOntologyBiologicalProcessfilopodium assembly

EPHB2 MYO10 SPAG6 TENM2 SRGAP2C

8.51e-05781185GO:0046847
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection assembly

EPHB2 TMEM67 NCKAP1 MYO10 SYNE1 SDCCAG8 TENM2 SRGAP2C

9.15e-052481188GO:0120032
GeneOntologyBiologicalProcesscellular response to fatty acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.63e-05421184GO:0071398
GeneOntologyBiologicalProcesssynaptic target recognition

YWHAZ SEMA3A

9.70e-0531182GO:0008039
GeneOntologyBiologicalProcessregulation of cell projection assembly

EPHB2 TMEM67 NCKAP1 MYO10 SYNE1 SDCCAG8 TENM2 SRGAP2C

9.94e-052511188GO:0060491
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

FAT4 HTRA2 USP9X CAT AKR1C4 SMOC2 AKR1C1 AKR1C2 FGF17 DDX5 BMP7 PELO GPC3 PTPRF AKR1C3

1.03e-0485011815GO:0071363
GeneOntologyBiologicalProcessC21-steroid hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.27e-04451184GO:0008207
GeneOntologyBiologicalProcessalcohol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.50e-04471184GO:0046164
GeneOntologyBiologicalProcessresponse to growth factor

FAT4 HTRA2 USP9X CAT AKR1C4 SMOC2 AKR1C1 AKR1C2 FGF17 DDX5 BMP7 PELO GPC3 PTPRF AKR1C3

1.56e-0488311815GO:0070848
GeneOntologyBiologicalProcesspositive regulation of reactive oxygen species metabolic process

AKR1C4 AKR1C1 AKR1C2 PTK2B AKR1C3

1.59e-04891185GO:2000379
GeneOntologyBiologicalProcessretinoid metabolic process

ABCA4 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.59e-04891185GO:0001523
GeneOntologyBiologicalProcessisoprenoid metabolic process

ABCA4 HTRA2 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.81e-041441186GO:0006720
GeneOntologyBiologicalProcessditerpenoid metabolic process

ABCA4 AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.06e-04941185GO:0016101
GeneOntologyBiologicalProcessaldehyde metabolic process

ABCA4 AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.16e-04951185GO:0006081
GeneOntologyBiologicalProcessreactive oxygen species metabolic process

CAT AKR1C4 AKR1C1 AKR1C2 PTK2B BMP7 PXDNL AKR1C3

2.73e-042911188GO:0072593
GeneOntologyBiologicalProcessprostaglandin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.97e-04561184GO:0006693
GeneOntologyBiologicalProcessprostanoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.18e-04571184GO:0006692
GeneOntologyBiologicalProcessregulation of filopodium assembly

EPHB2 MYO10 TENM2 SRGAP2C

3.18e-04571184GO:0051489
GeneOntologyBiologicalProcessketone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.18e-04571184GO:0042181
GeneOntologyBiologicalProcessresponse to calcium ion

AKR1C4 AKR1C1 AKR1C2 PTK2B PCDH15 AKR1C3

3.30e-041611186GO:0051592
GeneOntologyBiologicalProcessregulation of hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.40e-04581184GO:0032350
GeneOntologyBiologicalProcessneuron recognition

EPHB2 YWHAZ SEMA3A PTPRZ1

3.63e-04591184GO:0008038
GeneOntologyBiologicalProcessmesenchymal cell proliferation

FAT4 SYNE1 BMP7 GPC3

3.63e-04591184GO:0010463
GeneOntologyBiologicalProcesspositive regulation of neuron migration

SEMA3A SRGAP2C PTPRZ1

3.83e-04251183GO:2001224
GeneOntologyBiologicalProcesspositive regulation of epithelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.88e-04601184GO:1904037
GeneOntologyBiologicalProcessregulation of synapse organization

EPHB2 DOCK1 USP9X YWHAZ PTPRT PTK2B SRGAP2C PTPRF SRGAP2B

3.89e-043871189GO:0050807
GeneOntologyBiologicalProcessnegative regulation of cell projection organization

EPHB2 SEMA3A SRGAP2C PTPRF PTPRG PTPRZ1 ULK2

3.91e-042331187GO:0031345
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

FAT4 TENM2 CLDN8 PTPRT PTPRF HMCN1 PTPRG PCDH15

4.44e-043131188GO:0098742
GeneOntologyBiologicalProcesscell morphogenesis

EPHB2 CACNA1F NCKAP1 PLEKHG4 MYO10 USP9X SYNE1 GRHL2 SPAG6 TENM2 SEMA3A PTK2B BMP7 PTPRF PTPRZ1 PCDH15 ULK2

4.48e-04119411817GO:0000902
GeneOntologyBiologicalProcessregulation of synapse structure or activity

EPHB2 DOCK1 USP9X YWHAZ PTPRT PTK2B SRGAP2C PTPRF SRGAP2B

4.51e-043951189GO:0050803
GeneOntologyBiologicalProcesspremeiotic DNA replication

MCM2 MCM6

4.80e-0461182GO:0006279
GeneOntologyBiologicalProcessneuron projection fasciculation

EPHB2 SEMA3A PTPRZ1

5.39e-04281183GO:0106030
GeneOntologyBiologicalProcessaxonal fasciculation

EPHB2 SEMA3A PTPRZ1

5.39e-04281183GO:0007413
GeneOntologyBiologicalProcesssecondary metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.91e-04671184GO:0019748
GeneOntologyBiologicalProcessneuron projection morphogenesis

EPHB2 CACNA1F NCKAP1 PLEKHG4 USP9X SYNE1 SPAG6 TENM2 SEMA3A BMP7 PTPRF PTPRZ1 ULK2

6.82e-0480211813GO:0048812
GeneOntologyBiologicalProcessdendrite development

EPHB2 CACNA1F SYNE1 SEMA3A BMP7 SRGAP2C PTPRF PTPRZ1

6.93e-043351188GO:0016358
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

FAT4 PTPRT PTPRF HMCN1 PTPRG PCDH15

7.29e-041871186GO:0007156
GeneOntologyBiologicalProcessregulation of reactive oxygen species metabolic process

AKR1C4 AKR1C1 AKR1C2 PTK2B BMP7 AKR1C3

7.50e-041881186GO:2000377
GeneOntologyBiologicalProcessorganic hydroxy compound catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.17e-04731184GO:1901616
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

EPHB2 CACNA1F NCKAP1 PLEKHG4 USP9X SYNE1 SPAG6 TENM2 SEMA3A BMP7 PTPRF PTPRZ1 ULK2

8.27e-0481911813GO:0120039
GeneOntologyBiologicalProcessregulation of endothelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.60e-04741184GO:2000351
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

AKR1C4 AKR1C1 AKR1C2 DDX5 AKR1C3

8.81e-041291185GO:0048024
MousePhenoparturition failure

AKR1C4 AKR1C1 AKR1C2 ANTXR2 AKR1C3

3.03e-0910945MP:0012010
MousePhenoabnormal parturition

AKR1C4 AKR1C1 AKR1C2 ANTXR2 AKR1C3 GAB3

7.53e-0833946MP:0002907
MousePhenohypermyelination

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.10e-0711944MP:0010050
MousePhenoincreased oligodendrocyte number

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.31e-0613944MP:0010160
MousePhenoincreased circulating progesterone level

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.47e-0615944MP:0005186
MousePhenolong stride length

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.47e-0615944MP:0010540
MousePhenolong gestation period

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.47e-0615944MP:0002293
MousePhenoabnormal gestational length

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.46e-0618944MP:0002292
MousePhenodysmyelination

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.55e-0620944MP:0013438
MousePhenodecreased vocalization

ANK2 AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.36e-0546945MP:0020351
MousePhenodecreased oligodendrocyte number

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.18e-0525944MP:0009808
MousePhenoabnormal oligodendrocyte morphology

AKR1C4 AKR1C1 AKR1C2 PTPRZ1 AKR1C3

2.27e-0551945MP:0000953
MousePhenoincreased stereotypic behavior

HTRA2 AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.75e-0553945MP:0001409
MousePhenoprolonged diestrus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.60e-0530944MP:0009011
MousePhenoabnormal diestrus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.56e-0535944MP:0009010
MousePhenorespiratory system inflammation

MECOM NLRP1 AKR1C4 CRLF2 AKR1C1 AKR1C2 GPC3 AKR1C3

1.15e-04220948MP:0002405
MousePhenoenhanced coordination

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.19e-0438944MP:0003858
MousePhenoprolonged estrous cycle

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.32e-0439944MP:0009006
MousePhenolung inflammation

NLRP1 AKR1C4 CRLF2 AKR1C1 AKR1C2 GPC3 AKR1C3

2.46e-04185947MP:0001861
MousePhenoabnormal circulating progesterone level

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.48e-0450944MP:0005184
DomainG2F

NID2 HMCN1 NID1

2.52e-0731193SM00682
DomainALDOKETO_REDUCTASE_1

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.19e-07101194PS00798
DomainALDOKETO_REDUCTASE_2

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.19e-07101194PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.19e-07101194PS00063
DomainAldo/ket_reductase_CS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.19e-07101194IPR018170
DomainAldo/keto_reductase

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.19e-07101194IPR020471
DomainG2F

NID2 HMCN1 NID1

1.00e-0641193PF07474
DomainNIDOGEN_G2

NID2 HMCN1 NID1

1.00e-0641193PS50993
DomainGFP

NID2 HMCN1 NID1

1.00e-0641193IPR009017
DomainG2_nidogen/fibulin_G2F

NID2 HMCN1 NID1

1.00e-0641193IPR006605
Domain-

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.69e-061611943.20.20.100
DomainNADP_OxRdtase_dom

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.50e-06171194IPR023210
DomainAldo_ket_red

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.50e-06171194PF00248
DomainAldo/ket_red/Kv-b

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.50e-06171194IPR001395
DomainGFP-like

NID2 HMCN1 NID1

4.01e-05111193IPR023413
Domain-

NID2 HMCN1 NID1

4.01e-051111932.40.155.10
DomainPTPc

PTPRT PTPRF PTPRG PTPRZ1

7.88e-05361194SM00194
DomainTYR_PHOSPHATASE_PTP

PTPRT PTPRF PTPRG PTPRZ1

1.08e-04391194PS50055
DomainK_chnl_volt-dep_ERG

KCNH7 KCNH6

1.20e-0431192IPR003967
DomainsrGAP2

SRGAP2C SRGAP2B

1.20e-0431192IPR030252
DomainPTPase_domain

PTPRT PTPRF PTPRG PTPRZ1

1.32e-04411194IPR000242
DomainY_phosphatase

PTPRT PTPRF PTPRG PTPRZ1

1.32e-04411194PF00102
Domain-

NID2 SMOC2 NID1

1.61e-041711934.10.800.10
DomainThyroglobulin_1

NID2 SMOC2 NID1

1.61e-04171193IPR000716
DomainTHYROGLOBULIN_1_1

NID2 SMOC2 NID1

1.61e-04171193PS00484
DomainTY

NID2 SMOC2 NID1

1.61e-04171193SM00211
DomainTHYROGLOBULIN_1_2

NID2 SMOC2 NID1

1.61e-04171193PS51162
DomainThyroglobulin_1

NID2 SMOC2 NID1

1.61e-04171193PF00086
DomainFN3

EPHB2 CRLF2 PTPRT IGDCC4 PTPRF PTPRG PTPRZ1

1.84e-041851197SM00060
DomainFN3

EPHB2 CRLF2 PTPRT IGDCC4 PTPRF PTPRG PTPRZ1

2.87e-041991197PS50853
DomainFN3_dom

EPHB2 CRLF2 PTPRT IGDCC4 PTPRF PTPRG PTPRZ1

3.86e-042091197IPR003961
DomainNIDO_dom

NID2 NID1

3.98e-0451192IPR003886
DomainNIDO

NID2 NID1

3.98e-0451192SM00539
DomainNIDO

NID2 NID1

3.98e-0451192PF06119
DomainNIDO

NID2 NID1

3.98e-0451192PS51220
DomainYD

NID2 TENM2

3.98e-0451192IPR006530
DomainGrowth_fac_rcpt_

EPHB2 TMEM67 NID2 FAT4 HMCN1 NID1

4.92e-041561196IPR009030
DomainPTPc_motif

PTPRT PTPRF PTPRG PTPRZ1

5.44e-04591194SM00404
DomainTyr_Pase_cat

PTPRT PTPRF PTPRG PTPRZ1

5.44e-04591194IPR003595
DomaincEGF

NID2 HMCN1 NID1

5.89e-04261193PF12662
DomaincEGF

NID2 HMCN1 NID1

5.89e-04261193IPR026823
DomainMCM_N

MCM2 MCM6

5.94e-0461192PF14551
DomainMCM_CS

MCM2 MCM6

5.94e-0461192IPR018525
DomainMCM_N

MCM2 MCM6

5.94e-0461192IPR027925
Domainfn3

EPHB2 PTPRT IGDCC4 PTPRF PTPRG PTPRZ1

6.01e-041621196PF00041
Domain-

EPHB2 CRLF2 PTPRT IGDCC4 SEMA3A FAM187B PTPRF HMCN1 PTPRG PTPRZ1 PXDNL CD200

1.08e-03663119122.60.40.10
DomainYippee/Mis18/Cereblon

YPEL5 CRBN

1.10e-0381192IPR004910
DomainYippee-Mis18

YPEL5 CRBN

1.10e-0381192PF03226
DomainMCM_OB

MCM2 MCM6

1.10e-0381192PF17207
DomainMCM_OB

MCM2 MCM6

1.10e-0381192IPR033762
DomainMCM_2

MCM2 MCM6

1.10e-0381192PS50051
DomainMCM_1

MCM2 MCM6

1.10e-0381192PS00847
DomainEGF_CA

NID2 FAT4 TENM2 HMCN1 NID1

1.11e-031221195SM00179
DomainEGF-like_Ca-bd_dom

NID2 FAT4 TENM2 HMCN1 NID1

1.19e-031241195IPR001881
DomainTyr_Pase_AS

PTPRT PTPRF PTPRG PTPRZ1

1.22e-03731194IPR016130
DomainMCM

MCM2 MCM6

1.41e-0391192SM00350
DomainMCM_dom

MCM2 MCM6

1.41e-0391192IPR001208
DomainMCM

MCM2 MCM6

1.41e-0391192IPR031327
DomainMCM

MCM2 MCM6

1.41e-0391192PF00493
DomainPAS_9

KCNH7 KCNH6

1.75e-03101192PF13426
DomainIg-like_fold

EPHB2 CRLF2 PTPRT IGDCC4 SEMA3A FAM187B PTPRF HMCN1 PTPRG PTPRZ1 PXDNL CD200

1.83e-0370611912IPR013783
Domain-

NID2 TENM2 NID1

1.95e-033911932.120.10.30
DomainEGF_CA

NID2 FAT4 HMCN1 NID1

2.23e-03861194PF07645
DomainTYR_PHOSPHATASE_1

PTPRT PTPRF PTPRG PTPRZ1

2.23e-03861194PS00383
DomainTYR_PHOSPHATASE_dom

PTPRT PTPRF PTPRG PTPRZ1

2.32e-03871194IPR000387
DomainTYR_PHOSPHATASE_2

PTPRT PTPRF PTPRG PTPRZ1

2.32e-03871194PS50056
DomainEGF_dom

NID2 NID1

2.55e-03121192IPR024731
DomainABC_A

ABCA4 ABCA12

2.55e-03121192IPR026082
DomainEGF_3

NID2 NID1

2.55e-03121192PF12947
Domain-

PTPRT PTPRF PTPRG PTPRZ1

2.84e-039211943.90.190.10
DomainP-loop_NTPase

ABCA4 ERCC6L ABCA12 MYO10 MCM2 NLRP1 MCM6 PFKFB2 DDX5 GUF1 KIF9 UCK2 HELLS

2.93e-0384811913IPR027417
Domain6-blade_b-propeller_TolB-like

NID2 TENM2 NID1

3.14e-03461193IPR011042
DomainEGF_Ca-bd_CS

NID2 FAT4 HMCN1 NID1

3.44e-03971194IPR018097
DomainK_chnl_volt-dep_EAG/ELK/ERG

KCNH7 KCNH6

3.48e-03141192IPR003938
DomainLdl_recept_b

NID2 NID1

3.48e-03141192PF00058
DomainLDLRB

NID2 NID1

3.48e-03141192PS51120
DomainPH

RASA2 RASGRF2 PLEKHG4 MYO10 DGKH GAB3

3.50e-032291196PF00169
DomainEGF_CA

NID2 FAT4 HMCN1 NID1

3.70e-03991194PS01187
DomainProt-tyrosine_phosphatase-like

PTPRT PTPRF PTPRG PTPRZ1

3.70e-03991194IPR029021
DomainASX_HYDROXYL

NID2 FAT4 HMCN1 NID1

3.84e-031001194PS00010
DomainLY

NID2 NID1

4.00e-03151192SM00135
DomainLDLR_classB_rpt

NID2 NID1

4.00e-03151192IPR000033
DomainGalactosyl_T

B3GNT5 B3GALNT2

4.56e-03161192PF01762
DomainGlyco_trans_31

B3GNT5 B3GALNT2

4.56e-03161192IPR002659
DomainEGF-type_Asp/Asn_hydroxyl_site

NID2 FAT4 HMCN1 NID1

4.72e-031061194IPR000152
DomainCarb_anhydrase

PTPRG PTPRZ1

5.14e-03171192PF00194
DomainCarb_anhydrase

PTPRG PTPRZ1

5.14e-03171192SM01057
Domain-

PTPRG PTPRZ1

5.14e-031711923.10.200.10
DomainALPHA_CA_2

PTPRG PTPRZ1

5.14e-03171192PS51144
DomainCarbonic_anhydrase_a

PTPRG PTPRZ1

5.14e-03171192IPR001148
DomainPH_dom-like

RASA2 RASGRF2 PLEKHG4 MYO10 DGKH ARHGEF17 PTK2B GAB3

5.96e-034261198IPR011993
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.83e-079894M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.83e-079894M47817
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.74e-0711894M47812
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.02e-0613894M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.02e-0613894MM14747
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.42e-0614894M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.42e-0614894M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.42e-0614894M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.42e-0614894MM14748
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.92e-0615894MM14870
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C4 AKR1C1 AKR1C2 GPC3 AKR1C3

8.97e-0645895MM15344
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-0523894M1926
PathwayREACTOME_PREDNISONE_ADME

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-0523894MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.20e-0523894MM14741
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

ABCA4 AKR1C4 AKR1C1 AKR1C2 GPC3 AKR1C3

2.46e-0592896MM14881
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.71e-0528894MM15188
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.28e-0533894M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.28e-0533894MM14737
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.66e-0444894M499
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.81e-0445894MM14751
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

AKR1C4 AKR1C1 GPC3 AKR1C3

2.34e-0448894M27642
PathwayREACTOME_SIGNALING_BY_RETINOIC_ACID

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.53e-0449894MM15186
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.96e-0455894M14933
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

ABCA4 AKR1C4 AKR1C1 GPC3 AKR1C3

4.21e-04100895M27158
PathwayKEGG_MEDICUS_REFERENCE_DNA_REPLICATION_LICENSING

MCM2 MCM6 DBF4

4.47e-0424893M47857
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.89e-0461894MM14861
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.91e-0470894M16794
PathwayREACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX

MCM2 MCM6 DBF4

1.06e-0332893MM15368
PathwayKEGG_MEDICUS_REFERENCE_BREAK_INDUCED_REPLICATION

MCM2 MCM6

1.08e-038892M47840
PathwayPID_INTEGRIN_A4B1_PATHWAY

DOCK1 YWHAZ PTK2B

1.16e-0333893M277
PathwayREACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX

MCM2 MCM6 DBF4

1.16e-0333893M9694
PathwayREACTOME_SENSORY_PERCEPTION

ABCA4 AKR1C4 AKR1C1 AKR1C2 GPC3 AKR1C3

1.27e-03190896MM15687
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124420124700
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124410500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124416508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124419487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124414967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124410393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124415193432
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124431479646
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124415222881
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124416191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124415577209
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124410702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124417034817
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124417629694
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124429764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124410526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124417888864
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124417442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124428329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124416018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124417272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124419237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124418667791
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124428259989
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124421521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-10412448274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124416511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124410803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-104124434590152
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.54e-10412447789999
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-10512447737980
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-105124421851338
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-105124417872381
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-105124417064890
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-105124410672042
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-105124438788959
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-105124416984997
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.67e-105124418003893
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.30e-096124429107092
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.30e-096124419273550
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.30e-096124415860270
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.30e-096124415471942
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.30e-096124426748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.30e-096124417122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.30e-096124417255200
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.34e-097124426160177
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.34e-097124434843575
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.34e-097124422529366
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.34e-097124433127481
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.34e-097124412562828
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.34e-097124416337335
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-088124433584538
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-088124420837989
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-08812449224647
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.91e-089124433348080
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.18e-0810124436313771
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C1 AKR1C2 AKR1C3

4.42e-083124319320734
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C1 AKR1C2 AKR1C3

4.42e-083124331780644
Pubmed

Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans.

AKR1C4 AKR1C1 AKR1C3

4.42e-08312437626489
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C1 AKR1C2 AKR1C3

4.42e-083124321232532
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C1 AKR1C2 AKR1C3

4.42e-083124313678667
Pubmed

Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.45e-0812124421256921
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.45e-0812124428893949
Pubmed

A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.45e-0812124425774556
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-0713124411682476
Pubmed

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-0713124417062636
Pubmed

A link between lung androgen metabolism and the emergence of mature epithelial type II cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-0713124415117747
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-0713124424580729
Pubmed

Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.50e-0714124419955443
Pubmed

Placental endocrine function shapes cerebellar development and social behavior.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.50e-0714124434400844
Pubmed

Targeted Disruption of Lats1 and Lats2 in Mice Impairs Adrenal Cortex Development and Alters Adrenocortical Cell Fate.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.53e-0717124432243503
Pubmed

Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.

AKR1C1 AKR1C2 AKR1C3

4.40e-075124315212687
Pubmed

Functional dynamics of H3K9 methylation during meiotic prophase progression.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.72e-0719124417599069
Pubmed

A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.13e-0720124423636947
Pubmed

WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.13e-0720124424135228
Pubmed

Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.29e-0623124423685333
Pubmed

Genome-wide association study identifies five new schizophrenia loci.

TRIM26 SDCCAG8 PTPRG CCDC68

1.29e-0623124421926974
Pubmed

Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk.

AKR1C1 AKR1C2 AKR1C3

1.53e-067124319846565
Pubmed

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.84e-0625124426098214
Pubmed

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.17e-0626124423892084
Pubmed

Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells.

MCM2 MCM6 DBF4

2.45e-068124316899510
Pubmed

Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.53e-0627124417077188
Pubmed

Identification of differentially expressed genes in mouse spermatogenesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.53e-0627124414581517
Pubmed

Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.53e-0627124423471215
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

AKR1C4 AKR1C1 PTPRT PTPRG PTPRZ1 PCDH15 AKR1C3

2.85e-06171124720201926
Pubmed

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.95e-0628124429879378
Pubmed

Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.95e-0628124421820362
Pubmed

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.95e-0628124429212953
Pubmed

Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a criticial threonine residue of Cdc7 bY Cdks.

MCM2 MCM6 DBF4

3.66e-069124310846177
Pubmed

Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.12e-0632124434288113
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

EPHB2 PLEKHG4 DGKH IDE PFKFB2 NUP58 ITPRID1 GRHL2 PTPRZ1 PXDNL CSNK2A2 AKR1C3

6.72e-066861241229987050
Pubmed

Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.

NID2 BMP7 NID1

7.15e-0611124317023412
Pubmed

An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.28e-0637124421362171
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

DOCK1 SUPT20H TRIM26 MCM6 YWHAZ DDX5 MED24 CSNK2A2 HELLS

1.17e-05390124917643375
Pubmed

Interactions of the human MCM-BP protein with MCM complex components and Dbf4.

MCM2 MCM6 DBF4

1.23e-0513124322540012
Pubmed

Molecular cloning of two human liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase isoenzymes that are identical with chlordecone reductase and bile-acid binder.

AKR1C4 AKR1C1

1.26e-05212428172617
Pubmed

Relationship of human liver dihydrodiol dehydrogenases to hepatic bile-acid-binding protein and an oxidoreductase of human colon cells.

AKR1C1 AKR1C2

1.26e-05212428573067
Pubmed

Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.

AKR1C4 AKR1C3

1.26e-05212427650035
Pubmed

Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.

AKR1C1 AKR1C2

1.26e-052124211514561
Pubmed

Different domains in nidogen-1 and nidogen-2 drive basement membrane formation in skin organotypic cocultures.

NID2 NID1

1.26e-052124222623588
InteractionAKR1C4 interactions

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.22e-0881204int:AKR1C4
InteractionAKR1C1 interactions

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.38e-06201204int:AKR1C1
Cytoband10p15-p14

AKR1C1 AKR1C2 AKR1C3

3.82e-076124310p15-p14
CytobandEnsembl 112 genes in cytogenetic band chr10p15

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.08e-04901244chr10p15
GeneFamilyAldo-keto reductases

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.97e-0715854399
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRT PTPRF PTPRG PTPRZ1

2.56e-0621854813
GeneFamilyFibronectin type III domain containing

EPHB2 CRLF2 PTPRT IGDCC4 PTPRF PTPRG PTPRZ1

1.03e-05160857555
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASA2 RASGRF2 PLEKHG4 MYO10 DGKH GAB3

4.21e-04206856682
GeneFamilyMCM family

MCM2 MCM6

7.70e-0498521085
GeneFamilyATP binding cassette subfamily A

ABCA4 ABCA12

1.92e-0314852805
GeneFamilyCadherin related

FAT4 PCDH15

2.84e-031785224
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

RASGRF2 PLEKHG4 ARHGEF17

3.71e-0366853722
GeneFamilyRho GTPase activating proteins|F-BAR domain containing

SRGAP2C SRGAP2B

5.18e-03238521288
GeneFamilyBeta 3-glycosyltransferases

B3GNT5 B3GALNT2

5.64e-0324852426
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

IGDCC4 PTPRF HMCN1 PXDNL

7.01e-03161854593
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3

MCM6 AKR1C4 AKR1C1 AKR1C2 IGDCC4 BMP7 GPC3 AKR1C3 NID1

1.10e-10791219MM535
CoexpressionWANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP

AKR1C4 AKR1C1 AKR1C2 MTUS1 AKR1C3

7.47e-07371215MM630
CoexpressionGOLDRATH_IMMUNE_MEMORY

NCKAP1 AKR1C4 AKR1C1 AKR1C2 ANTXR2 AKR1C3

8.08e-07691216MM621
CoexpressionRAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP

NID2 AKR1C4 ARHGEF17 AKR1C1 AKR1C2 PTK2B AKR1C3 CD200 HELLS

8.46e-072191219MM1237
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.82e-07171214MM826
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3

MCM6 IGDCC4 BMP7 GPC3 AKR1C3 NID1

1.22e-06741216M1277
CoexpressionVARELA_ZMPSTE24_TARGETS_DN

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.03e-06451215MM1173
CoexpressionGSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP

KLHL6 CAT DGKH ZNF285 TENM2 PHKB SENP7 SEC14L1

3.57e-061951218M8006
CoexpressionLIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.27e-06241214MM766
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.07e-06251214MM480
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.08e-05301214MM853
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_B

TMEM67 NID2 ABCA4 B3GNT5 SDCCAG8 AKR1C4 AKR1C1 AKR1C2 MTUS1 DBF4 CCDC68 AKR1C3

1.72e-0558412112MM1080
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_INTERMEDIATE_LYMPHATIC_ENDO_CELL

EPHB2 ABCA4 MAN1A1 SYNE1 CCDC122 AKR1C1 AKR1C2 SEMA3A AKR1C3 ULK2

1.80e-0540212110M45754
CoexpressionDESCARTES_ORGANOGENESIS_INTERMEDIATE_MESODERM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.27e-05361214MM3660
CoexpressionBREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP

AKR1C4 AKR1C1 AKR1C2 LSM12 AKR1C3

2.41e-05741215MM769
CoexpressionNABA_BASEMENT_MEMBRANES

NID2 COL6A5 HMCN1 NID1

3.47e-05401214M5887
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_1

NID2 MYO10 COBLL1 MECOM PELO HMCN1 PTPRG NID1 DNAJC1 CD200

3.87e-0544012110M39039
CoexpressionGSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN

RASA2 KRT34 IDE ARHGEF17 CLDN8 PTPRZ1 KDSR

3.98e-051991217M8352
CoexpressionGSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_DN

CUL4B RASA2 TRIM26 PSME2 RGS14 PCDH15 SEC14L1

4.11e-052001217M3973
CoexpressionGSE17721_0.5H_VS_24H_CPG_BMDC_DN

SYNE1 PTK2B GOLGA7 DNAJC1 CRBN CD200 SEC14L1

4.11e-052001217M4129
CoexpressionGSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN

KLHL6 MYO10 GOLGA7 YPEL5 MED12L CRBN CD200

4.11e-052001217M5603
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP

CUL4B MCM2 MCM6 IDE YWHAZ GUF1 DBF4 GOLGA7 UCK2 PACC1 SRGAP2B HELLS

4.47e-0564412112M10501
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_A

AKR1C4 AKR1C1 AKR1C2 FBXL4 PHKB AKR1C3 GAB3

5.59e-052101217MM958
CoexpressionCARRILLOREIXACH_HEPATOBLASTOMA_VS_NORMAL_UP

EPHB2 TMEM67 B3GNT5 ERCC6L EML6 MECOM MCM6 SPAG6 IGDCC4 KCNH6 GPC3 PTPRG ODAM PACC1

6.47e-0589112114M45033
CoexpressionMARTINEZ_RB1_AND_TP53_TARGETS_UP

NSUN4 MCM6 CAT AKR1C4 IDE SMOC2 AKR1C1 AKR1C2 PTPRF PTPRG PTPRZ1 AKR1C3

8.50e-0568912112MM1041
CoexpressionINGRAM_SHH_TARGETS_UP

AKR1C4 SMOC2 AKR1C1 AKR1C2 AKR1C3 NID1

8.83e-051561216MM550
CoexpressionMARTINEZ_TP53_TARGETS_UP

NSUN4 MCM6 CAT AKR1C4 IDE SMOC2 AKR1C1 AKR1C2 PTPRF PTPRG PTPRZ1 AKR1C3

9.10e-0569412112MM1039
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6

AKR1C4 AKR1C1 AKR1C2 MED24 AKR1C3

1.12e-041021215MM872
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

DOCK1 NID2 FAT4 B3GNT5 RASGRF2 MYO10 MECOM SMOC2 ARHGEF17 GRHL2 BMP7 ANTXR2 GPC3 HMCN1 MTUS1

1.30e-04107412115M1941
CoexpressionLAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB

DOCK1 SDCCAG8 MECOM DDX5 PTPRG MTUS1

1.37e-041691216M39230
CoexpressionDESCARTES_FETAL_THYMUS_THYMIC_EPITHELIAL_CELLS

SLC46A2 KCNH7 SYNE1 EML6 PTPRT BMP7 PTPRF

1.43e-042441217M40312
CoexpressionWOOD_EBV_EBNA1_TARGETS_UP

NCKAP1 AKR1C1 AKR1C2 AKR1C3 UCK2

1.60e-041101215M1696
CoexpressionZHENG_GLIOBLASTOMA_PLASTICITY_UP

EPHB2 MCM2 MCM6 LSM12 SEMA3A DBF4 HELLS

1.62e-042491217M1796
CoexpressionCUI_TCF21_TARGETS_2_DN

NID2 MAN1A1 RASA2 MYO10 USP9X DGKH TENM2 PTPRG MTUS1 YPEL5 MED12L NID1 ULK2

1.64e-0485412113M1533
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

MAN1A1 RASA2 USP9X SYNE1 NLRP1 PSME2 YWHAZ DDX5 PTK2B RGS14 ZNF800 ANTXR2 PELO GOLGA7 YPEL5 GAB3 CRBN SENP7

1.69e-04149212118M40023
CoexpressionMARSON_FOXP3_TARGETS_DN

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.73e-04601214MM847
CoexpressionHEVNER_CORTEX_RADIAL_GLIA_PROGENITORS

DOCK1 ERCC6L MCM2 MCM6 IDE IGDCC4 SEMA3A DBF4 HELLS

1.83e-044321219MM419
CoexpressionIBRAHIM_NRF2_UP

NCKAP1 B3GALNT2 IDE AKR1C1 AKR1C2 PELO CSNK2A2 AKR1C3 UCK2 PACC1

1.87e-0453312110M42510
CoexpressionZHENG_GLIOBLASTOMA_PLASTICITY_UP

EPHB2 MCM2 MCM6 LSM12 SEMA3A DBF4 HELLS

1.96e-042571217MM1231
CoexpressionDEN_INTERACT_WITH_LCA5

USP9X YWHAZ CSNK2A2

2.31e-04261213M1380
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

CUL4B MYO10 USP9X THUMPD3 BMP7 MTUS1 WASHC5 DBF4 NID1 DNAJC1 HELLS

2.35e-0465612111M18979
CoexpressionCUI_TCF21_TARGETS_2_DN

NID2 MAN1A1 RASA2 MYO10 USP9X DGKH TENM2 PTPRG MTUS1 YPEL5 MED12L NID1 ULK2

2.39e-0488812113MM1018
CoexpressionNADLER_HYPERGLYCEMIA_AT_OBESITY

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.50e-04661214MM631
CoexpressionSERVITJA_ISLET_HNF1A_TARGETS_DN

AKR1C4 PFKFB2 AKR1C1 AKR1C2 AKR1C3

2.50e-041211215MM935
CoexpressionDARWICHE_PAPILLOMA_RISK_LOW_UP

AKR1C4 IDE AKR1C1 AKR1C2 AKR1C3 UCK2

2.73e-041921216MM497
CoexpressionNABA_CORE_MATRISOME

NID2 COL6A5 SMOC2 HMCN1 PXDNL NID1 DMBT1

2.96e-042751217M5884
CoexpressionENGELMANN_CANCER_PROGENITORS_DN

AKR1C1 AKR1C2 BMP7 AKR1C3

2.96e-04691214M9246
CoexpressionDEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN

EPHB2 MYO10 ARHGEF17 PTPRF SEC16A C1orf216 SEC14L1

3.02e-042761217M3063
CoexpressionNABA_ECM_GLYCOPROTEINS

NID2 SMOC2 HMCN1 PXDNL NID1 DMBT1

3.05e-041961216M3008
CoexpressionTABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_EPITHELIAL_CELL_AGEING

MYO10 COBLL1 CAT AKR1C4 GRHL2 AKR1C1 AKR1C2 WASHC5 AKR1C3 DMBT1

3.11e-0456812110MM3824
CoexpressionCHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN

CUL4B NID2 FAT4 B3GNT5 SEMA3A ANTXR2 PTPRG AKR1C3 GPR176

3.15e-044651219M9192
CoexpressionVALK_AML_CLUSTER_1

COBLL1 MECOM SPAG6

3.21e-04291213M19844
CoexpressionGSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP

DOCK1 HTRA2 TENM2 RGS14 CRBN MOCS2

3.31e-041991216M3915
CoexpressionGSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_UP

FAT4 ABCA4 B3GNT5 AKR1C4 RGS14 KDSR

3.31e-041991216M7420
CoexpressionGSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_DN

KLHL6 PLEKHG4 SDCCAG8 PSME2 PTK2B ZNF800

3.40e-042001216M8253
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN

MYO10 SEMA3A CSNK2A2 MED12L UCK2 SEC14L1

3.40e-042001216M8854
CoexpressionGSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_UP

THUMPD3 MCM2 RGS14 YPEL5 ULK2 SEC14L1

3.40e-042001216M7746
CoexpressionGSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP

ERCC6L HTRA2 IDE PSME2 NUP58 LSM12

3.40e-042001216M7611
CoexpressionGSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN

DOCK1 B3GNT5 YWHAZ NID1 DNAJC1 CD200

3.40e-042001216M8962
CoexpressionGSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP

NSUN4 TRIM26 PSME2 ZUP1 ULK2 CRBN

3.40e-042001216M9051
CoexpressionONDER_CDH1_TARGETS_2_DN

ABCA12 COBLL1 MECOM GRHL2 AKR1C1 SEMA3A PTPRF MTUS1 PTPRZ1

3.57e-044731219M4306
CoexpressionRAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP

NID2 AKR1C4 ARHGEF17 PTK2B CD200 HELLS

3.78e-042041216M1844
CoexpressionBROWN_MYELOID_CELL_DEVELOPMENT_DN

AKR1C4 IDE AKR1C1 AKR1C2 AKR1C3

4.59e-041381215MM1151
CoexpressionLI_CISPLATIN_RESISTANCE_DN

AKR1C1 GPC3 AKR1C3

4.73e-04331213M10150
CoexpressionHE_LIM_SUN_FETAL_LUNG_C3_SCG3_POS_LYMPHATIC_ENDOTHELIAL_CELL

ABCA4 ANK2 B3GNT5 SYNE1 IDE AKR1C1 AKR1C2 SEMA3A PTPRF AKR1C3

5.02e-0460412110M45760
CoexpressionHUANG_DASATINIB_SENSITIVITY_UP

EPHB2 MYO10 ANTXR2 AKR1C3

5.21e-04801214M3015
CoexpressionMCBRYAN_PUBERTAL_BREAST_5_6WK_UP

AKR1C4 AKR1C1 AKR1C2 CLDN8 AKR1C3

5.39e-041431215MM989
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_200

ERCC6L COBLL1 MECOM GRHL2 CLDN8 SEMA3A PTPRZ1

1.98e-051451217gudmap_kidney_e10.5_UretericTip_HoxB7_200
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_100

COBLL1 MECOM GRHL2 CLDN8 PTPRZ1

3.74e-05661215gudmap_kidney_e10.5_UretericTip_HoxB7_100
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

DOCK1 CUL4B MYO10 USP9X SDCCAG8 IDE PFKFB2 NUP58 GRHL2 MED12L

5.82e-0537512110gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_500

ERCC6L COBLL1 MECOM GRHL2 CLDN8 SEMA3A GPC3 HMCN1 PTPRZ1 HELLS

7.09e-0538412110gudmap_kidney_e10.5_UretericTip_HoxB7_500
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 EML6 SMOC2 GRHL2 AKR1C2 PTPRT BMP7 CD200

3.50e-081761248327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 MYO10 SYNE1 COBLL1 EML6 MECOM GRHL2 PXDNL

6.07e-081891248830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 TENM2 PTPRT PTK2B ANTXR2 PTPRZ1 CCDC68 SEC14L1

6.32e-0819012481bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

FAT4 MYO10 TENM2 GPC3 HMCN1 PTPRG PCDH15 NID1

7.14e-081931248acad568621ed677031797b8c2e34dafea798d681
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 RASGRF2 MECOM DGKH HMCN1 PTPRG CCDC68 NID1

8.04e-081961248ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 COBLL1 MECOM DGKH HMCN1 PTPRG CCDC68 NID1

8.36e-08197124862c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 COBLL1 MECOM DGKH HMCN1 PTPRG CCDC68 NID1

8.36e-08197124816f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 ANK2 MYO10 SYNE1 COL6A5 GPC3 PXDNL NID1

9.03e-081991248a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 RASGRF2 MYO10 COBLL1 MECOM PELO HMCN1 CCDC68

9.03e-08199124863c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 COL6A5 PTPRT SEMA3A HMCN1 PTPRG PTPRZ1

3.35e-071601247c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 COL6A5 PTPRT SEMA3A HMCN1 PTPRG PTPRZ1

3.35e-07160124725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 EML6 SMOC2 GRHL2 AKR1C2 PTPRT CD200

6.62e-071771247da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A5 ITPRID1 IGDCC4 BMP7 GPC3 PXDNL PCDH15

7.41e-07180124708ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 KCNH7 SPAG6 SEMA3A ANTXR2 PTPRZ1 PXDNL

8.90e-07185124710da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPHB2 MECOM COL6A5 TENM2 BMP7 PCDH15 CCDC68

1.03e-0618912474f9608b84d135268a17455661870c46ae8554a24
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ANK2 SMOC2 GPC3 HMCN1 PTPRG PCDH15 NID1

1.06e-0619012473a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 ABCA4 MECOM TENM2 CLDN8 PTPRF SEC14L1

1.10e-0619112475a5b5402a077b3189ca156f2bac5f47ad780aebf
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 ABCA4 MECOM TENM2 CLDN8 PTPRF SEC14L1

1.10e-06191124778bcce497920cc5b3bef083eab50deb1cc82cd2e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 DOCK1 COBLL1 EML6 DGKH GRHL2 AKR1C1

1.10e-061911247d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT4 ANK2 GPC3 HMCN1 PTPRG PCDH15 NID1

1.10e-0619112476688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNH7 TENM2 PTPRT PTK2B BMP7 ANTXR2 PTPRZ1

1.14e-06192124725460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 TENM2 GPC3 HMCN1 PTPRG PCDH15 NID1

1.18e-06193124799525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 TENM2 GPC3 HMCN1 PTPRG PCDH15 NID1

1.18e-061931247b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 MYO10 TENM2 GPC3 HMCN1 PTPRG PCDH15

1.22e-061941247011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK2 SYNE1 COL6A5 IGDCC4 GPC3 PXDNL PCDH15

1.22e-06194124760622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK1 FAT4 MECOM DGKH HMCN1 PTPRG KIAA0825

1.22e-0619412470b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK2 SYNE1 COL6A5 GPC3 PXDNL PCDH15 NID1

1.22e-0619412476e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 MYO10 MECOM HMCN1 CCDC68 NID1 SEC14L1

1.22e-061941247ea5e1bc8d9e27cabfe1fb833ca47ec0893593b12
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NID2 MYO10 MECOM HMCN1 CCDC68 NID1 SEC14L1

1.22e-061941247cceb7c88492bb6cd531e1c2651638da1ddf30931
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 SYNE1 NLRP1 TENM2 BMP7 GPR176 CD200

1.22e-0619412471374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KCNH7 MAN1A1 COBLL1 MECOM CLDN8 HMCN1 MED12L

1.27e-061951247a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

RASGRF2 MYO10 SYNE1 MECOM CCDC68 CD200 SEC14L1

1.27e-06195124750a193475db1bb1e05b8590225a553688c372c14
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYO10 PELO PTPRG MTUS1 CCDC68 AKR1C3 NID1

1.40e-0619812470a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 MYO10 MECOM AKR1C1 PTPRF AKR1C3 DMBT1

1.40e-061981247a4543d636501a1b5b46c14a661ce9d169947c82c
ToppCell3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 MYO10 MECOM SMOC2 PTPRF AKR1C3 DMBT1

1.40e-061981247e8bfae3888b2406b5629b576cb02913b3297337e
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ANK2 MYO10 SYNE1 COL6A5 GPC3 PXDNL NID1

1.45e-06199124730d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 ANK2 SYNE1 COL6A5 IGDCC4 GPC3 PCDH15

1.45e-0619912478b86c69aaf60feff53aa782559cfece7342a23de
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COBLL1 MECOM AKR1C1 HMCN1 CCDC68 AKR1C3 NID1

1.50e-06200124786ec951234015ced7126b016199e5869a0f22478
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ANK2 SYNE1 GPC3 HMCN1 PTPRG NID1

1.50e-062001247b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

NID2 ANK2 MYO10 COL6A5 GPC3 PXDNL NID1

1.50e-062001247a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COBLL1 MECOM AKR1C1 MTUS1 CCDC68 AKR1C3 NID1

1.50e-062001247c239e6f5d23caa9a59b83e9b352b2d6a691dcb28
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

ANK2 SYNE1 COL6A5 GPC3 PXDNL PCDH15 NID1

1.50e-062001247bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DOCK1 TMEM67 PLEKHG4 MECOM CCDC122 SPAG6

6.03e-06161124646b5d80d2d521fb69752aba4c10383e715a32002
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NCKAP1 SYNE1 GRHL2 PTPRF PTPRG C1orf216

7.18e-06166124689e2b8453180983533faccb4275867861876d7ee
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPHB2 MCM6 SMOC2 TENM2 GPC3 HELLS

7.95e-061691246335619507857383c3b0b507cdf05d786ed59e585
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 PTPRT PTK2B ANTXR2 CCDC68 MED12L

9.09e-0617312469a2d42f8d9cb834856522661d524abb91c4637c5
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KCNH7 NCKAP1 SYNE1 YWHAZ PTK2B RGS14

9.71e-061751246ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellsystemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

EPHB2 DOCK1 KCNH7 CAT HMCN1 PACC1

9.71e-061751246c58a1f02d1e559d3638fe1500e960e82a8a7187b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KCNH7 NCKAP1 SYNE1 YWHAZ PTK2B RGS14

9.71e-06175124621f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FAT4 ANK2 SEMA3A PTPRG GPR176 CD200

1.04e-0517712463d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1F NID2 AKR1C1 ZUP1 GOLGA7 MED12L

1.04e-0517712462dd6dd5193bda9ba1c6b299ec47890fdc92f88b1
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NID2 MYO10 DGKH ARHGEF17 CCDC68 NID1

1.07e-051781246185b44700f06ec58b3c09c80520502166c965fd6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COBLL1 PTPRT PTK2B ANTXR2 PTPRZ1 CCDC68

1.10e-0517912468766a5a066091879f521acfc612abf563ff78808
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR1C4 FAM187B ANTXR2 CCDC68 NID1 GPR176

1.14e-051801246280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR1C4 FAM187B ANTXR2 CCDC68 NID1 GPR176

1.14e-051801246fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL6A5 ITPRID1 BMP7 GPC3 PXDNL PCDH15

1.14e-0518012469b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ANK2 COBLL1 SMOC2 PTPRG CD200

1.18e-0518112469d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 SYNE1 SEMA3A BMP7 GPR176 CD200

1.18e-0518112465f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 COL6A5 TENM2 GPC3 HMCN1 PCDH15

1.18e-0518112469ede19228ba5c0668a9c06c915510b95585216ef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 SYNE1 SEMA3A BMP7 GPR176 CD200

1.18e-051811246c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ANK2 COBLL1 SMOC2 PTPRG CD200

1.21e-051821246eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ANK2 CAT SMOC2 AKR1C1 MED12L

1.25e-05183124683592c332b1e82673f993d37c7f480befdc3dcda
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6L MCM2 MCM6 DBF4 UCK2 HELLS

1.25e-0518312466c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F FAT4 ABCA4 ABCA12 HMCN1 PCDH15

1.29e-0518412462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F FAT4 ABCA4 ABCA12 HMCN1 PCDH15

1.29e-051841246ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F FAT4 ABCA4 ABCA12 HMCN1 PCDH15

1.29e-0518412462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERCC6L EML6 MCM2 DBF4 UCK2 HELLS

1.33e-05185124647c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1F ABCA4 AKR1C1 AKR1C2 AKR1C3 CD200

1.33e-051851246241ea1e178fffef9e7df971de739e794332d5173
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EML6 SMOC2 GRHL2 AKR1C1 BMP7 CD200

1.37e-0518612465c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COBLL1 DGKH ARHGEF17 PXDNL CCDC68 NID1

1.41e-051871246fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

FAT4 RASGRF2 COBLL1 MECOM PTPRG SEC14L1

1.41e-05187124640ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

MYO10 COL6A5 GPC3 HMCN1 PTPRG PCDH15

1.41e-051871246e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ANK2 COBLL1 CAT SMOC2 PTPRG

1.41e-051871246c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCelldroplet-Fat-SCAT-30m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF2 MYO10 SYNE1 MECOM PTPRG CD200

1.46e-051881246e901a9bdf00b8e91806f445af66647373bf62661
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF2 MYO10 SYNE1 MECOM PTPRG CD200

1.46e-0518812465cf060bb8adaefa9964187195d67993c1248ef47
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

COBLL1 MECOM GRHL2 PTPRG MTUS1 DMBT1

1.46e-051881246ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK2 PFKFB2 TENM2 DDX5 PTPRF SEC16A

1.46e-051881246a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO10 COBLL1 EML6 MECOM GRHL2 HELLS

1.46e-051881246e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 ABCA4 ANK2 MECOM TENM2 CLDN8

1.46e-05188124614e120b20e76baa07b6510a94f0c2dcdfdd52357
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF2 MYO10 SYNE1 MECOM PTPRG CD200

1.46e-051881246449f9602df3c83b2110eb479a00d428d1b55b423
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB2 ABCA4 ANK2 MECOM TENM2 CLDN8

1.50e-051891246443359d90fafae0c1de6bdcce9e8c95df6ea4de8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 EML6 MECOM GRHL2 CLDN8 HELLS

1.50e-051891246bfc76a72b600d641c8fe58346e5d8986c34f3981
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

RASGRF2 SYNE1 MECOM PTPRG CD200 SEC14L1

1.50e-051891246fe49852ba15f948b384d6b4c258927c70b741357
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NID2 ARHGEF17 HMCN1 MTUS1 PXDNL NID1

1.50e-0518912469c2492c38f27e4c699b40680652e4c64911cce52
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK2 MYO10 COL6A5 GPC3 PXDNL PCDH15

1.50e-0518912462a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA4 ANK2 COBLL1 CAT SMOC2 PTPRG

1.55e-0519012461cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 COBLL1 MECOM GRHL2 GPC3 PTPRG

1.55e-051901246bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

MYO10 SYNE1 DGKH PTPRG CCDC68 SEC14L1

1.55e-0519012467f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 COBLL1 MECOM GRHL2 GPC3 PTPRG

1.55e-051901246b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 SYNE1 COBLL1 MECOM DGKH GRHL2

1.55e-0519012463fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK2 COL6A5 IGDCC4 GPC3 PCDH15 GPR176

1.55e-05190124645df8fee00f8949937863159d7aa042e72748d9b
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 SYNE1 COBLL1 CCDC68 DNAJC1 SEC14L1

1.55e-0519012460e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO10 COBLL1 EML6 MECOM GRHL2 HELLS

1.55e-05190124611d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DGKH ARHGEF17 HMCN1 PXDNL NID1 GPR176

1.55e-051901246d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO10 COBLL1 EML6 MECOM GRHL2 HELLS

1.55e-051901246b7f8c2bb9459f1d7c1690069dd5a25a81a57cc84
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

MECOM ITPRID1 GRHL2 AKR1C1 MTUS1 PTPRZ1

1.55e-05190124651ca9ef4df3220487152fcf684147730637c7cc1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK2 COL6A5 IGDCC4 GPC3 PXDNL PCDH15

1.59e-051911246b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPHB2 COBLL1 MECOM GRHL2 GPC3 PTPRG

1.59e-0519112462fa1b9e76a0ed2d2f0de74349e266cf4a5f51aad
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EPHB2 NID2 KCNH7 SMOC2 AKR1C2 GPC3

1.59e-051911246156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

RASGRF2 MYO10 SYNE1 MECOM CCDC68 SEC14L1

1.59e-051911246c8a0c2af119bc34a8f694a7d30642f28002c84b9
ComputationalIntermediate filaments.

B3GNT5 TENM2 AKR1C1 CLDN8 AKR1C3

2.05e-0475785MODULE_154
ComputationalIntermediate filaments and keratins.

B3GNT5 TENM2 AKR1C1 CLDN8 AKR1C3

2.78e-0480785MODULE_357
ComputationalGenes in the cancer module 297.

B3GNT5 TENM2 AKR1C1 CLDN8 AKR1C3

2.78e-0480785MODULE_297
Drugcloxazolam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.85e-1041224ctd:C005522
DrugPregnanes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.85e-1041224ctd:D011278
Drugtetralol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.85e-1041224ctd:C019106
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.85e-1041224ctd:C018156
Drugoctyl gallate

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.00e-09101225ctd:C016627
DrugHydroxysteroids

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.91e-0951224ctd:D006914
Drugcresolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.91e-0951224ctd:C010092
DrugMedazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.17e-0861224ctd:D008472
DrugNitrazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.40e-0881224ctd:D009567
Drug4-hydroxybenzoic acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.68e-0891224ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.68e-0891224ctd:D004092
Drugcyclopentanol

AKR1C1 AKR1C2 AKR1C3

1.50e-0731223ctd:C016327
Drugcyclopentanone

AKR1C1 AKR1C2 AKR1C3

1.50e-0731223ctd:C007201
Drug5-dihydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

1.50e-0731223ctd:C454687
Drug4-benzoylbenzoic acid

AKR1C1 AKR1C2 AKR1C3

1.50e-0731223ctd:C058818
Drugdichloro(4-cymene)ruthenium(II)

AKR1C1 AKR1C2 AKR1C3

1.50e-0731223ctd:C530610
DrugGlycyrrhetinic Acid

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.59e-07241225ctd:D006034
DrugDihydroxydihydrobenzopyrenes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.52e-07111224ctd:D004101
Drugchlordecone alcohol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.52e-07111224CID000013946
DrugPhenolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.76e-07121224ctd:D020113
DrugDMBA-3,4-dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.40e-07131224CID000050096
Drugflunisolide

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.40e-07131224ctd:C007734
Drugtetrahydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

5.98e-0741223ctd:C009413
Druggliquidone

AKR1C1 AKR1C2 AKR1C3

5.98e-0741223ctd:C010969
DrugDBD-H

AKR1C4 AKR1C1 AKR1C3

5.98e-0741223CID000131382
Drug5-alpha-Dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.54e-07141224ctd:D043582
Drug1-acenaphthenol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.54e-07141224CID000022750
DrugMeclofenamic Acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.54e-07141224ctd:D008469
DrugNSC86000

AKR1C1 AKR1C2 AKR1C3

1.49e-0651223CID000257630
Drugo-quinone

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.61e-06411225CID000011421
Drugoxcarbazepine

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.86e-06191224ctd:C036006
DrugAC1L93E5

AKR1C4 AKR1C1 AKR1C3

2.97e-0661223CID000412383
DrugEstazolam

AKR1C1 AKR1C2 AKR1C3

2.97e-0661223ctd:D004949
Drug3-hydroxyhexobarbital

AKR1C4 AKR1C2 AKR1C3

2.97e-0661223CID000439898
DrugGlipizide

AKR1C1 AKR1C2 AKR1C3

2.97e-0661223ctd:D005913
Drugacenaphthene-1-ol

AKR1C1 AKR1C2 AKR1C3

2.97e-0661223ctd:C023723
Drugbenzo(a)pyrene-7,8-dione

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.56e-06201224ctd:C076588
DrugChrysenes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.56e-06201224ctd:D002911
DrugFlunitrazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.38e-06211224ctd:D005445
Drug4-hydroxyequilenin-o-quinone

AKR1C1 AKR1C2 AKR1C3

5.17e-0671223ctd:C117714
Drugzomepirac

AKR1C1 AKR1C2 AKR1C3

5.17e-0671223ctd:C020549
Drugbenzene dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.33e-06221224CID000000418
Drug2-cyclohexen-1-ol

AKR1C4 AKR1C2 AKR1C3

8.24e-0681223CID000013198
Drug9,10-phenanthrenequinone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.10e-06251224ctd:C005399
DrugPregnanolone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.10e-06251224ctd:D011280
Drugbenzo(a)pyrene 7,8-dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.21e-05311224ctd:C017228
Drug4-pyridinone

SYNE1 IDE AKR1C2

2.40e-05111223CID000012290
DrugNADP

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3 KDSR

2.43e-051071226ctd:D009249
Drugalpha-methylcinnamic acid

AKR1C1 AKR1C3

2.85e-0521222ctd:C510582
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

2.85e-0521222DB07768
Drugbaccharin

AKR1C2 AKR1C3

2.85e-0521222ctd:C012764
Drugchlordecone

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.01e-05671225CID000000299
Drugfenamic acid

AKR1C1 AKR1C2 AKR1C3

3.19e-05121223ctd:C001209
Drug3,4-dichloroaniline

MYO10 KRT34 AKR1C1 AKR1C2 ANTXR2 PTPRZ1 AKR1C3

3.87e-051711227ctd:C014464
Drug4-formyl-benzoate

AKR1C4 AKR1C1 AKR1C2

4.13e-05131223CID000012088
DrugPiloty's acid

SYNE1 NLRP1 CAT

4.13e-05131223CID000069033
DrugDiazepam

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.88e-05741225ctd:D003975
DrugDydrogesterone

AKR1C1 AKR1C2 AKR1C3

5.23e-05141223ctd:D004394
Drug6-.beta.-Naltrexol

AKR1C4 AKR1C1 AKR1C2

5.23e-05141223CID000631219
Drug20 alpha-dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.18e-05401224CID000008956
Drugdrospirenone

AKR1C4 AKR1C1 AKR1C2

6.52e-05151223ctd:C035144
Drugcinnamyl alcohol

CAT AKR1C1 AKR1C2 AKR1C3

7.50e-05421224ctd:C020722
Drug1,10-phenanthroline

CAT AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.98e-05821225ctd:C025205
Drug9-cis-retinal

AKR1C4 AKR1C1 AKR1C3

7.99e-05161223ctd:C031390
DrugPyrimethamine [58-14-0]; Up 200; 16uM; PC3; HT_HG-U133A

SUPT20H NLRP1 PFKFB2 YWHAZ PTK2B PACC1 DMBT1

8.58e-0519412274194_UP
DrugLY 294002; Up 200; 10uM; HL60; HT_HG-U133A

EPHB2 MYO10 MECOM AKR1C4 KCNH6 GPC3 MTUS1

8.58e-0519412272687_UP
Drug0198306-0000 [212631-61-3]; Down 200; 10uM; PC3; HT_HG-U133A

EPHB2 DOCK1 SUPT20H SYNE1 NLRP1 YWHAZ ULK2

9.44e-0519712277069_DN
Drugbenzo(a)pyrene-1,6-quinone

AKR1C1 AKR1C2 AKR1C3

9.66e-05171223ctd:C030233
DrugFlufenamic Acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.86e-05451224ctd:D005439
Drugnaphthalene-1,2-dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.86e-05451224CID000000362
Drugcloxazolam

AKR1C1 AKR1C2 AKR1C3

1.15e-04181223CID000002816
DrugRuthenium Compounds

AKR1C1 AKR1C2 AKR1C3

1.15e-04181223ctd:D017975
Drugbenzo(a)pyrene-3,6-quinone

AKR1C1 AKR1C2 AKR1C3

1.15e-04181223ctd:C018003
DrugAC1L8ZBW

AKR1C4 AKR1C1 AKR1C2

1.37e-04191223CID000435356
Drugfenofibric acid

CAT AKR1C1 AKR1C2 AKR1C3

1.61e-04511224ctd:C006012
Drugandrostane-3,17-dione

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.61e-04511224CID000000443
DrugAC1LAOJR

NLRP1 CAT

1.70e-0441222CID000472179
DrugMiADMSA

NLRP1 CAT

1.70e-0441222CID000164448
Drugconiferaldehyde

AKR1C1 AKR1C2 AKR1C3

1.86e-04211223ctd:C075384
DrugDutasteride

AKR1C1 AKR1C2 AKR1C3

1.86e-04211223ctd:D000068538
Drug1 C2

PLEKHG4 AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.04e-041001225CID005327152
DrugAC1O3IHE

NLRP1 CAT CD200

2.15e-04221223CID006329358
Druggramine

SYNE1 CAT GPR176

2.15e-04221223CID000006890
DrugHexestrol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.17e-04551224ctd:D006589
Drugchrysene

KLHL6 CAT SMOC2 TENM2 AKR1C1 YWHAZ DDX5 MED24 HMCN1 PTPRG PTPRZ1 YPEL5 GAB3 CD200

2.40e-0487112214ctd:C031180
Drug2'-Monophosphoadenosine 5'-Diphosphoribose

AKR1C1 AKR1C2 AKR1C3

2.46e-04231223DB03461
Drug1,2-dihydroxynaphthalene

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.49e-04571224CID000011318
Drugphenolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.66e-04581224CID000004764
DrugNSC36919

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.66e-04581224CID000235496
DrugGlyburide

CAT AKR1C1 AKR1C2 AKR1C3

2.66e-04581224ctd:D005905
DrugFlurbiprofen

SMOC2 AKR1C1 AKR1C2 AKR1C3 HELLS

2.80e-041071225ctd:D005480
Drugmedazepam

AKR1C1 AKR1C2 AKR1C3

2.80e-04241223CID000004041
Drugfarnesal

AKR1C2 AKR1C3

2.82e-0451222ctd:C084519
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2 AKR1C3

6.23e-0831183C0027661
DiseaseHermaphroditism

AKR1C1 AKR1C2 AKR1C3

6.20e-0751183C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2 AKR1C3

6.20e-0751183C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2 AKR1C3

6.20e-0751183C0033804
DiseaseIntersex Conditions

AKR1C1 AKR1C2 AKR1C3

6.20e-0751183C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2 AKR1C3

6.20e-0751183C2930619
DiseaseCystic kidney

TMEM67 FAT4 SDCCAG8

1.24e-0661183C0022679
DiseaseDisorders of Sex Development

AKR1C1 AKR1C2 AKR1C3

2.16e-0671183C0036875
DiseaseCystic Kidney Diseases

TMEM67 FAT4 SDCCAG8

1.00e-05111183C1691228
DiseaseMALE PSEUDOHERMAPHRODITISM: DEFICIENCY OF TESTICULAR 17,20-DESMOLASE

AKR1C4 AKR1C2

1.59e-0521182C1839840
Disease46,XY disorder of sex development due to testicular 17,20-desmolase deficiency

AKR1C4 AKR1C2

1.59e-0521182cv:C1839840
Disease46,XY sex reversal 8 (is_implicated_in)

AKR1C4 AKR1C2

1.59e-0521182DOID:0111773 (is_implicated_in)
Disease46,XY SEX REVERSAL 8

AKR1C4 AKR1C2

1.59e-0521182614279
Diseasenidogen-2 measurement

NID2 NID1

9.46e-0541182EFO_0020608
Diseasemethionine measurement

ZNF285 PCDH15 NID1

1.52e-04261183EFO_0009771
DiseaseAbnormalities, Drug-Induced

CAT CRBN

1.57e-0451182C0000771
Diseaselow density lipoprotein cholesterol measurement, body mass index

COBLL1 MCM6

2.35e-0461182EFO_0004340, EFO_0004611
Diseasecortolone glucuronide (1) measurement

AKR1C2 AKR1C3

2.35e-0461182EFO_0800552
Diseasenephrolithiasis

DGKH RGS14 DMBT1

3.12e-04331183EFO_0004253
DiseaseEndometrioma

AKR1C1 AKR1C2 DDX5 BMP7 AKR1C3

4.84e-041611185C0269102
DiseaseEndometriosis

AKR1C1 AKR1C2 DDX5 BMP7 AKR1C3

4.84e-041611185C0014175
Diseaseresponse to anticoagulant

SMOC2 OTUD3 HELLS

5.95e-04411183GO_0061476
Diseaseejection fraction measurement

DGKH SMOC2 HMCN1

6.85e-04431183EFO_0005527
Diseaselong QT syndrome (implicated_via_orthology)

KCNH7 KCNH6

6.99e-04101182DOID:2843 (implicated_via_orthology)
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

TRIM26 SYNE1 SEMA3A CCDC68

7.36e-041011184EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseasecell growth regulator with EF hand domain protein 1 measurement

NID2 NID1

8.52e-04111182EFO_0801461
Diseaseurate measurement, bone density

SYNE1 COL6A5 TENM2 FBXL4 PTPRG CSNK2A2 SEC16A DMBT1 CRBN

8.75e-046191189EFO_0003923, EFO_0004531
DiseaseDrug habituation

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C0013170
DiseaseDrug abuse

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C0013146
DiseasePrescription Drug Abuse

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C4316881
DiseaseSubstance-Related Disorders

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C0236969
DiseaseDrug Use Disorders

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C0013222
DiseaseDrug Dependence

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C1510472
DiseaseSubstance Dependence

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C0038580
DiseaseSubstance Use Disorders

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

DOCK1 SYNE1 TENM2 PCDH15

1.19e-031151184C0029231
DiseaseBardet-Biedl Syndrome

TMEM67 SDCCAG8

1.20e-03131182C0752166
DiseaseSubstance abuse problem

DOCK1 SYNE1 TENM2 PCDH15

1.23e-031161184C0740858
DiseaseMalignant neoplasm of breast

NID2 ABCA4 ANK2 RASGRF2 SYNE1 B3GALNT2 MECOM CAT SPAG6 SEMA3A PHKB PACC1

1.26e-03107411812C0006142
DiseaseMalignant neoplasm of stomach

FAT4 PTPRT BMP7 PTPRF PTPRG AKR1C3

1.34e-033001186C0024623
Disease1-methylurate measurement

SEMA3A PTPRF

1.40e-03141182EFO_0021173
DiseaseBMI-adjusted leptin measurement

COBLL1 ZNF800

1.61e-03151182EFO_0007793
Disease1,3,7-trimethylurate measurement

TRIM26 PTPRF

1.61e-03151182EFO_0021172
DiseaseDisorder of eye

CACNA1F TMEM67 ABCA4 SDCCAG8 PCDH15

1.66e-032121185C0015397
Diseaseinsulin resistance

DOCK1 ANK2 COBLL1

1.72e-03591183EFO_0002614
Diseasetestosterone measurement

ANK2 ERCC6L COBLL1 MECOM AKR1C4 AKR1C2 SEMA3A RGS14 ZNF800 PTPRF HMCN1 PTPRG AKR1C3

1.79e-03127511813EFO_0004908
Diseaseresponse to paliperidone, schizophrenia symptom severity measurement

RASGRF2 CCDC122 TENM2 PTPRT HMCN1

1.80e-032161185EFO_0007925, EFO_0007927
Diseaseresponse to methotrexate

AKR1C1 AKR1C2

1.83e-03161182GO_0031427
Diseaseovarian carcinoma

ABCA4 METTL15P1 MECOM NLRP1 PTPRG PTPRZ1

1.88e-033211186EFO_0001075
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

COBLL1 MCM6

2.07e-03171182EFO_0004611, EFO_0007800
DiseaseFetal Alcohol Syndrome

ERCC6L CAT

2.07e-03171182C0015923
DiseaseColorectal Carcinoma

ABCA4 ANK2 RASGRF2 ABCA12 SYNE1 ITPRID1 PTPRT ODAM NID1

2.08e-037021189C0009402
Diseasesevere acute respiratory syndrome, COVID-19

EPHB2 USP9X DCAF8L2 SMOC2 TENM2 CRLF2 SEMA3A

2.18e-034471187EFO_0000694, MONDO_0100096
DiseaseAge-related macular degeneration

ABCA4 HMCN1

2.33e-03181182cv:C0242383
Diseaseserum hepcidin measurement

EML6 DGKH

2.33e-03181182EFO_0004504
DiseaseBardet-Biedl syndrome

TMEM67 SDCCAG8

2.33e-03181182cv:C0752166
DiseaseNeoplastic Cell Transformation

CAT AKR1C1 AKR1C2 AKR1C3

2.39e-031391184C0007621
Diseasehip circumference

NID2 COBLL1 MCM6 PTPRT HMCN1 PTPRG

2.43e-033381186EFO_0005093
DiseaseSclerocystic Ovaries

AKR1C1 AKR1C2 AKR1C3 HELLS

2.71e-031441184C1136382
Diseasestroke

ANK2 SEMA3A PTPRF PTPRG

2.71e-031441184EFO_0000712
DiseasePolycystic Ovary Syndrome

AKR1C1 AKR1C2 AKR1C3 HELLS

2.71e-031441184C0032460
Diseaseulcerative colitis, Crohn's disease

OTUD3 CD200

2.87e-03201182EFO_0000384, EFO_0000729
Diseasecortisol measurement

DGKH BMP7

2.87e-03201182EFO_0005843
Diseasegastric ulcer

MECOM ZNF800

3.17e-03211182EFO_0009454
Diseasevitiligo (is_implicated_in)

NLRP1 CAT

3.17e-03211182DOID:12306 (is_implicated_in)
Diseaseintellectual disability (implicated_via_orthology)

CUL4B ANK2 YWHAZ

3.41e-03751183DOID:1059 (implicated_via_orthology)
Diseaseprostate cancer (is_marker_for)

HTRA2 PTK2B BMP7 AKR1C3

3.62e-031561184DOID:10283 (is_marker_for)
Diseaseunipolar depression, bipolar disorder

FAT4 SYNE1 TENM2 PXDNL

3.62e-031561184EFO_0003761, MONDO_0004985
Diseasesmoking status measurement, diastolic blood pressure

SDCCAG8 MECOM NLRP1 BMP7

3.87e-031591184EFO_0006336, EFO_0006527
DiseaseLiver Cirrhosis, Experimental

NID2 PSME2 SMOC2 AKR1C1 YWHAZ BMP7 AKR1C3 NID1 HELLS

3.96e-037741189C0023893
Diseasefree androgen index

COBLL1 AKR1C4 AKR1C2 PTPRF PTPRG AKR1C3

4.00e-033741186EFO_0007005

Protein segments in the cluster

PeptideGeneStartEntry
RTQRNYLVQTEEQYI

PTPRG

1096

P23470
SYNEQRIRENIQVFE

AKR1C4

271

P17516
VGQRFLVNRVQDYIQ

PFKFB2

221

O60825
NDDNVTQVRAFYVNV

CAT

436

P04040
TQVRAFYVNVLNEEQ

CAT

441

P04040
VDRLNITFYENQITA

ABCA4

946

P78363
SYNEQRIRQNVQVFE

AKR1C3

271

P42330
RVENYLISTANEFVQ

ABCA12

1881

Q86UK0
RGYLQVNVTVQDIND

FAT4

231

Q6V0I7
TTIRVYFNILDVNDN

FAT4

1926

Q6V0I7
LDRESQSFYNLVVQV

FAT4

2006

Q6V0I7
EIYNFVQQLAERFVS

ANTXR2

61

P58335
SVAQAVQHLQVQERY

C1orf216

146

Q8TAB5
AVLAYSNVQEREAQF

CRBN

121

Q96SW2
AQRLFENYQTQSEEV

CCDC68

131

Q9H2F9
DNETFRISVYQVLQE

BMP7

186

P18075
RNFAQSNQYQVVDDI

DBF4

316

Q9UBU7
NAETQFRQLVAIYEV

DNAJC1

101

Q96KC8
QENVVQNEIIVYPEN

COBLL1

516

Q53SF7
EIVLENNYTAFQNAR

FGF17

131

O60258
QQFEETVRTLNNLYA

GOLGA7

41

Q7Z5G4
EYQFAVNNDTTELQV

IGDCC4

476

Q8TDY8
INLDQEEVYRTQVVE

RASA2

66

Q15283
ERVAGALQAQVEYNQ

GOLGA8S

316

H3BPF8
ERVAGELQAQVEYNQ

GOLGA8F;

111

Q08AF8
EVFNQRLEQEYNASV

GUF1

411

Q8N442
EETIYQNYQRIRIQE

MCM2

366

P49736
NLVACQINDQIFYRV

MECOM

161

Q03112
QINDQIFYRVVADIA

MECOM

166

Q03112
IVQDQYVQEARQVFE

ARHGEF17

586

Q96PE2
TTQIQQYENVFIFET

ANKAR

251

Q7Z5J8
QIQESVTFASQVYRE

ANK2

1306

Q01484
VVQNEQFDLIVNVFS

OVOS1

691

Q6IE37
VIITFRAQGEQEYQN

CACNA1F

1136

O60840
FNQQLSTTIQEEFYR

MCM6

71

Q14566
QEIFYTAIVNRTIAN

HELLS

476

Q9NRZ9
YIIQNFVQILNSEEF

KLHL6

196

Q8WZ60
QEQRLQGEVVAFDYQ

LSM12

21

Q3MHD2
FNQQVRARIYEVEQQ

MED12L

416

Q86YW9
VQRYQEFINTLQFQV

KIAA0825

581

Q8IV33
EAQLYRQFTTTVQVV

GPR176

36

Q14439
ENFQQVIDRTVSLYE

ITPRID1

76

Q6ZRS4
ARNELQTVYEAFVQQ

MTUS1

981

Q9ULD2
QNAAVFQEAFEIVVR

GPC3

106

P51654
ILINFRTTYVNQNEE

KCNH7

466

Q9NS40
QRVDYVQVDEQKTQA

GAB3

556

Q8WWW8
AAIQDFQVRQYIEQL

KIAA1109

1036

Q2LD37
VINFRTTYVNTNDEV

KCNH6

316

Q9H252
TRELAQQVQQVAAEY

DDX5

176

P17844
QVRVAELINASYFNN

DCAF8L2

296

P0C7V8
TNQDVINAIEQDYRL

EPHB2

831

P29323
QVLSQEQYERVLAEN

NLRP1

1406

Q9C000
QQLSVDSVFVLYNQE

NID1

631

P14543
QQTRQQQYEEQIPFY

ODAM

166

A1E959
DQFDQAVVLNQLRYS

MYO10

646

Q9HD67
REYEAREQTDQTQVQ

METTL15P1

41

P0C7V9
VFNQFRVVLSQQEQE

KIF9

421

Q9HAQ2
QRNYLVQTEEQYVFI

PTPRZ1

1971

P23471
ENADYVEQAIIQTVR

OVOS2

706

Q6IE36
QIQIIYFNLETVQVT

CRLF2

31

Q9HC73
VQTREPYEVAQFNVE

DGKH

156

Q86XP1
QSIENYVQIDITRVF

NCKAP1

751

Q9Y2A7
YNTTFQERVANQRIE

HMCN1

1271

Q96RW7
ELLANQYSIQVQVED

NSUN4

326

Q96CB9
AQRVNLVQTEEQYVF

PTPRT

1121

O14522
QVQVVTQDEREQLYT

CD200

31

P41217
VEFRQETSVVNYIDQ

PACC1

256

Q9H813
IVQNLEAENYNIESA

OTUD3

251

Q5T2D3
TQQLNVDRVFALYND

NID2

721

Q14112
TRYFVIIQANDRAQN

PCDH15

226

Q96QU1
ATVDSVYAREQINQQ

PXDNL

876

A1KZ92
VYAREQINQQTAYID

PXDNL

881

A1KZ92
QRYNDIIQQDFVDSF

B3GNT5

151

Q9BYG0
VQNAEDVYEAVRTQS

HTRA2

421

O43464
ERVAGALQAQVEYNQ

GOLGA8DP

111

Q0D2H9
EQRVVIFEQTQYDVP

GRHL2

181

Q6ISB3
VSEQIVSFYRVNEVQ

DOCK1

1421

Q14185
ETERQIYQQDSAIEN

CCDC122

71

Q5T0U0
FQSQDYVELTFEQQV

FBXL4

121

Q9UKA2
FQRNITVKLYQAEQE

B3GALNT2

171

Q8NCR0
QLNRYFTQQEISDAI

COL6A5

681

A8TX70
YSEVFEAINITNNER

CSNK2A2

51

P19784
NVNAEISVFEVNIRF

MAN1A1

271

P33908
IISQQYNFDRDNTEV

IDE

911

P14735
SDIEQEAQINYDRQV

EML6

631

Q6ZMW3
RQVVQYEIDFQDVTT

FAM187B

101

Q17R55
TNNTQLRVDYVIFDN

FAM187B

206

Q17R55
IQQTFQQYASLREEE

PTK2B

231

Q14289
QNNYRVTVIFRDVQL

DMBT1

2041

Q9UGM3
EAYNETFSNRVIINE

SEC14L1

96

Q92503
SVDVSQDYNQVENVI

KDSR

91

Q06136
RVFQDRQYQIDAAIV

CUL4B

841

Q13620
YIQQRVQKAQFLVEF

ERCC6L

696

Q2NKX8
QIIYNTDEVSFIQNL

PHKB

191

Q93100
FRILVQQFEVQLQQY

NUP58

346

Q9BVL2
YTVVFRDINSQQELQ

PTPRF

951

P10586
LQQEIFRYIRNTVGQ

TMEM67

966

Q5HYA8
VRNQIIFAVRQEYVE

MOCS2

51

O96033
IQQNVADILFVRTSY

USP9X

2271

Q93008
VQNTVQNLREYLEVE

SENP7

946

Q9BQF6
VLQVFEQYQKARTQF

SPAG6

6

O75602
VEQLLQNYVSFIENS

SYNE1

536

Q8NF91
VDLNQVLNETRSQYE

KRT34

261

O76011
QELYQVAQEQVRQGE

PLEKHG4

496

Q58EX7
EIRQFQQTSYRIDHQ

RASGRF2

1191

O14827
QREASAYEQVKQVLQ

SDCCAG8

331

Q86SQ7
FSENTLQFYNERVVI

MED24

651

O75448
QTLVQNEAVFVQYLD

TENM2

531

Q9NT68
ANQQETEQFYFTVRE

SRGAP2C

441

P0DJJ0
NQQETEQFYFTVREC

SRGAP2B

441

P0DMP2
ALERFYEQVVQAIQR

PELO

181

Q9BRX2
QVEVFRQNLFQEAEE

PSME2

16

Q9UL46
DVNYQFTQIVVDRVD

SEMA3A

426

Q14563
IVDQSQQAYQEAFEI

YWHAZ

141

P63104
SYNEQRIRQNVQVFE

AKR1C1

271

Q04828
SYNEQRIRQNVQVFE

AKR1C2

271

P52895
RVSAFIENNIVVFEN

CLDN8

31

P56748
ANAIIRDFYNSIVNV

CLDN8

141

P56748
NKVVNLQYSEVQDRV

YPEL5

46

P62699
QEEVSRIINYNVEQE

WASHC5

771

Q12768
YENVENLEFVQNQEV

SEC16A

456

O15027
YTQEQARKEFQQVFI

SMOC2

96

Q9H3U7
YEEDVRIQNAINIAQ

TMEM232

471

C9JQI7
DAERVVNQYQELVQN

SUPT20H

401

Q8NEM7
VQVAARQQEELLYQV

TEX13C

76

A0A0J9YWL9
TQQLAQEARNIYQEF

RGS14

111

O43566
LQDQRQYIVAEFEQG

TRIM26

181

Q12899
QNEVDYRQKQVVILS

UCK2

46

Q9BZX2
VDNLFVVVQEFQDYQ

THUMPD3

91

Q9BV44
YQIQESVVVDQISQL

ULK2

861

Q8IYT8
NTLERNFERINTVQY

ZUP1

56

Q96AP4
LEDQQQRAISNFYII

SLC46A2

66

Q9BY10
IETNQNAVFQYISRT

ZNF800

136

Q2TB10
LQISENENYVVNAII

ZNF285

116

Q96NJ3