Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentpostsynaptic density

DLG5 ATP7A PSD CPEB3 PSD3 GRIN2B ABLIM1 PTPRS MACF1 PPP1R9B GNG3

1.84e-0545110611GO:0014069
GeneOntologyCellularComponentasymmetric synapse

DLG5 ATP7A PSD CPEB3 PSD3 GRIN2B ABLIM1 PTPRS MACF1 PPP1R9B GNG3

3.08e-0547710611GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization

DLG5 ATP7A PSD CPEB3 PSD3 GRIN2B ABLIM1 PTPRS MACF1 PPP1R9B GNG3

4.98e-0550310611GO:0099572
GeneOntologyCellularComponentneuron to neuron synapse

DLG5 ATP7A PSD CPEB3 PSD3 GRIN2B ABLIM1 PTPRS MACF1 PPP1R9B GNG3

7.06e-0552310611GO:0098984
GeneOntologyCellularComponentcanonical inflammasome complex

CARD8 NLRP9 GSDMD

9.78e-05181063GO:0061702
GeneOntologyCellularComponentsuper elongation complex

AFF3 AFF4

3.77e-0461062GO:0032783
GeneOntologyCellularComponentNLRP3 inflammasome complex

CARD8 GSDMD

6.99e-0481062GO:0072559
GeneOntologyCellularComponentcell body

DAB2IP MAP2K4 ATP7A GRIN2B KCNB2 AKAP12 TIAM2 STAU1 PTPRS PPP1R9B ELK1 ULK1 GNG3

8.43e-0492910613GO:0044297
GeneOntologyCellularComponentneuronal cell body

DAB2IP MAP2K4 ATP7A GRIN2B KCNB2 AKAP12 TIAM2 STAU1 PTPRS PPP1R9B ELK1 ULK1

1.07e-0383510612GO:0043025
GeneOntologyCellularComponentsomatodendritic compartment

DAB2IP MAP2K4 ATP7A PSD CPEB3 GRIN2B KCNB2 AKAP12 TIAM2 STAU1 PTPRS PPP1R9B ELK1 ULK1 GNG3

1.33e-03122810615GO:0036477
GeneOntologyCellularComponentunconventional myosin complex

MYO9A MYO18B

1.36e-03111062GO:0016461
DomainPeptidase_C69

SCRN1 SCRN2

8.66e-0531012PF03577
DomainPeptidase_C69

SCRN1 SCRN2

8.66e-0531012IPR005322
DomainHMG_boxA_CS

HMGB1 HMGB2

8.66e-0531012IPR017967
DomainTF_AF4/FMR2

AFF3 AFF4

1.73e-0441012IPR007797
DomainAF-4

AFF3 AFF4

1.73e-0441012PF05110
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

MIIP ATXN2L DLG5 HIVEP1 ERCC6L MYO9A PSD3 KDM3B NARS2 CARD8 FAM83H ABLIM1 BAIAP2L1 PIK3C2B CNKSR3 FMN2 FIP1L1 MACF1 DNMBP SRRM2 HECTD1 TNS3 KIF2C

1.71e-158611072336931259
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DAB2IP GPRASP1 DMXL2 MAP2K4 DPYSL4 DIDO1 GRIN2B TTC3 AKAP12 ZNF462 ABLIM1 PTPRS CNKSR3 MACF1 PPP1R9B CABIN1 UNC79 AFF4 KIF2C

1.17e-109631071928671696
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

DLG5 EP400 HMGB1 DIDO1 LARP4 STK10 ABLIM1 BAIAP2L1 MACF1 RPRD2 ASPSCR1 SRRM2 TNS3

2.56e-094721071338943005
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PDS5B ATXN2L NUP50 HIVEP1 EP400 HMGB1 DIDO1 HMGB2 HMGB1P1 STAU1 BRCA1 BAZ2A FIP1L1 RPRD2 SRRM2 ZNF281 AFF4

5.62e-099541071736373674
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PDS5B ATXN2L HIVEP1 EP400 ERCC6L KDM3B DIDO1 POLR1G STK10 ABLIM1 BAZ2A FIP1L1 PLA2G4A DNMBP SRRM2

1.61e-087741071515302935
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ATXN2L NUP50 EP400 ERCC6L KDM3B DPYSL4 DIDO1 AKAP12 STAU1 ABLIM1 BAZ2A MACF1 PPP1R9B RPRD2 ZNF281 AFF4

2.85e-089341071633916271
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

PDS5B EP400 AFF3 ZNF462 BRCA1 RPRD2 ZNF281 AFF4 KIF2C

3.12e-08222107937071664
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DAB2IP DMXL2 PSD3 KDM3B SCRN1 ZNF462 ABLIM1 MACF1 RPRD2

3.50e-08225107912168954
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PDS5B ATXN2L NUP50 HIVEP1 EP400 TOGARAM2 KDM3B HMGB1 DIDO1 HMGB2 STAU1 STK10 BRCA1 FIP1L1 SRRM2 ZNF281 KIF2C

4.66e-0811031071734189442
Pubmed

Protein phosphatase 1α interacting proteins in the human brain.

MIIP STAU1 SH3RF2 PPP1R9B RPRD2 ULK1

6.31e-0867107622321011
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

PDS5B ATXN2L EP400 KDM3B DIDO1 BAZ2A FIP1L1 SRRM2 ZNF281 AFF4

1.09e-073411071032971831
Pubmed

HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoter.

HMGB1 HMGB2 TP73

1.13e-074107311748232
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

DAB2IP ATXN2L DMXL2 CPEB3 GRIN2B ABLIM1 FMN2 MACF1 GNG3 SRRM2

1.28e-073471071017114649
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DAB2IP ABCC3 EP400 NRF1 KDM3B TTC3 TIAM2 FAM83H STK10 PIK3C2B PTPRS TMEM132A ULK1 CABIN1 DNMBP HECTD1

2.79e-0711051071635748872
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ATXN2L DLG5 HIVEP1 EP400 MYO9A BAIAP2L1 PIK3C2B MACF1 DNMBP ANKRD52 TP73 KIF2C

2.81e-075881071238580884
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ATXN2L DLG5 ATP7A ERCC6L MYO9A PSD3 THSD1 AKAP12 STAU1 ABLIM1 BAIAP2L1 MACF1 KIF2C

2.90e-077081071339231216
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PSD EP400 POLR1G FAM83H BRCA1 BAZ2A LTN1 FMN2 FIP1L1 MACF1 SRRM2 ZNF281 ANKRD52 AFF4 TP73 SPATC1L

3.19e-0711161071631753913
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

DAB2IP ATXN2L NUP50 DIDO1 POLR1G STK10 FIP1L1 PLA2G4A RPRD2 SRRM2 ANKRD52

4.62e-075031071116964243
Pubmed

Protein phosphatase 1γ isoforms linked interactions in the brain.

B4GAT1 STAU1 SH3RF2 PPP1R9B RPRD2

9.25e-0757107523080069
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DAB2IP GPRASP1 ATXN2L DMXL2 MAP2K4 ACADM PSD3 SCRN1 GRIN2B KCNB2 STAU1 ABLIM1 TENM1 MACF1 PPP1R9B

2.20e-0611391071536417873
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ATXN2L LARP4 TTC3 AKAP12 STAU1 BRCA1 FIP1L1 MACF1 PPP1R9B DNMBP ZNF281 TNS3

2.47e-067241071236232890
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ATXN2L EP400 ERCC6L KDM3B LARP4 STAU1 ABLIM1 GLE1 FIP1L1 RPRD2 HECTD1 TNS3

2.80e-067331071234672954
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PDS5B HIVEP1 KDM3B DIDO1 MYSM1 ZNF462 BRCA1 BAZ2A CABIN1 ZNF281 AFF4

2.90e-066081071136089195
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

KDM3B DIDO1 FIP1L1 RPRD2 SRRM2 ZNF281

3.22e-06130107635545047
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

NUP50 EP400 KDM3B DIDO1 FIP1L1 RPRD2

3.84e-06134107625452129
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

PDS5B EP400 MYO9A POLR1G LARP4 FAM83H STAU1 BAZ2A LTN1 FIP1L1 MACF1 SRRM2 ZNF281 ANKRD52 TNS3 KIF2C

3.89e-0613531071629467282
Pubmed

Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2.

HMGB1 HMGB2 ZNF462 BRCA1 CABIN1

4.16e-0677107519505873
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DAB2IP PDS5B EP400 PSD3 ABLIM1 BAZ2A MACF1 ULK1 SRRM2

4.92e-06407107912693553
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PDS5B DLG5 DMXL2 EP400 HMGB1 DPYSL4 DIDO1 STAU1 ZNF462 FIP1L1 MACF1 SRRM2 ZNF281 AFF4

6.05e-0610821071438697112
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

DAB2IP ATP7A PSD3 AKAP12 STK10 ABLIM1 BAIAP2L1 PIK3C2B MACF1

6.46e-06421107936976175
Pubmed

Cloning and analysis of an HMG gene from the lamprey Lampetra fluviatilis: gene duplication in vertebrate evolution.

HMGB1 HMGB2

9.38e-06210729016958
Pubmed

Evidence for a shared structural role for HMG1 and linker histones B4 and H1 in organizing chromatin.

HMGB1 HMGB2

9.38e-06210728599938
Pubmed

TAp73 regulates ATP7A: possible implications for ageing-related diseases.

ATP7A TP73

9.38e-062107230530920
Pubmed

The combination of a nuclear HMGB1-positive and HMGB2-negative expression is potentially associated with a shortened survival in patients with pancreatic ductal adenocarcinoma.

HMGB1 HMGB2

9.38e-062107225060178
Pubmed

cDNA sequence and structure of a trout HMG-2 gene. Evidence for a trout-specific 3'-untranslated region.

HMGB1 HMGB2

9.38e-06210727607539
Pubmed

HMGB proteins and arthritis.

HMGB1 HMGB2

9.38e-062107228916968
Pubmed

Recent integrations of mammalian Hmg retropseudogenes.

HMGB1 HMGB2

9.38e-062107217406091
Pubmed

BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma.

BRCA1 TP73

9.38e-062107220807817
Pubmed

Interactions of HMGB Proteins with the Genome and the Impact on Disease.

HMGB1 HMGB2

9.38e-062107234680084
Pubmed

Association of HMGB1 and HMGB2 genetic polymorphisms with lung cancer chemotherapy response.

HMGB1 HMGB2

9.38e-062107224684392
Pubmed

The nonspecific DNA-binding and -bending proteins HMG1 and HMG2 promote the assembly of complex nucleoprotein structures.

HMGB1 HMGB2

9.38e-06210728339930
Pubmed

Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks.

HMGB1 HMGB2

9.38e-06210729600082
Pubmed

Indirect regulation of HMGB1 release by gasdermin D.

HMGB1 GSDMD

9.38e-062107232917873
Pubmed

Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2.

HMGB1 HMGB2

9.38e-062107211262228
Pubmed

Association of chromatin proteins high mobility group box (HMGB) 1 and HMGB2 with mitotic chromosomes.

HMGB1 HMGB2

9.38e-062107212925773
Pubmed

The HMG-1 box protein family: classification and functional relationships.

HMGB1 HMGB2

9.38e-06210727784217
Pubmed

Anti-high mobility group box 1 and box 2 non-histone chromosomal proteins (HMGB1/HMGB2) antibodies and anti-Saccharomyces cerevisiae antibodies (ASCA): accuracy in differentially diagnosing UC and CD and correlation with inflammatory bowel disease phenotype.

HMGB1 HMGB2

9.38e-062107222644337
Pubmed

Properties of Human Embryonic Stem Cells and Their Differentiated Derivatives Depend on Nonhistone DNA-Binding HMGB1 and HMGB2 Proteins.

HMGB1 HMGB2

9.38e-062107227863459
Pubmed

Dysregulation of ribosome-associated quality control elicits cognitive disorders via overaccumulation of TTC3.

TTC3 LTN1

9.38e-062107236917672
Pubmed

Conformational difference in HMGB1 proteins of human neutrophils and lymphocytes revealed by epitope mapping of a monoclonal antibody.

HMGB1 HMGB2

9.38e-062107215496585
Pubmed

Association Study of SLCO1B3 and ABCC3 Genetic Variants in Gallstone Disease.

ABCC3 SLCO1B3

9.38e-062107235328066
Pubmed

Involvement of high mobility group B proteins in cisplatin-induced cytotoxicity in squamous cell carcinoma of skin.

HMGB1 HMGB2

9.38e-062107219435426
Pubmed

The Effect of HMGB1 and HMGB2 on Transcriptional Regulation Differs in Neuroendocrine and Adenocarcinoma Models of Prostate Cancer.

HMGB1 HMGB2

9.38e-062107238542079
Pubmed

Overexpression of high mobility group (HMG) B1 and B2 proteins directly correlates with the progression of squamous cell carcinoma in skin.

HMGB1 HMGB2

9.38e-062107218798064
Pubmed

Correlation of serum HMGB1 and HMGB2 levels with clinical symptoms in allergic rhinitis children.

HMGB1 HMGB2

9.38e-062107237713866
Pubmed

Nonhistone Proteins HMGB1 and HMGB2 Differentially Modulate the Response of Human Embryonic Stem Cells and the Progenitor Cells to the Anticancer Drug Etoposide.

HMGB1 HMGB2

9.38e-062107233076532
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

NUP50 EP400 KDM3B DIDO1 BRCA1 FIP1L1 RPRD2 ZNF281

1.06e-05339107830415952
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

PDS5B ABCC3 ATP7A AKAP12 FAM83H STAU1 STK10 ABLIM1 BAIAP2L1 CNKSR3 MACF1

1.40e-057191071135337019
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

NUP50 EP400 KDM3B DIDO1 STAU1 BRCA1 RPRD2 ZNF281

1.54e-05357107837059091
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PDS5B CPEB3 PSD3 CARD8 DNMBP

1.65e-05102107510231032
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

DLG5 KCNB2 ABLIM1 TENM1 FIP1L1 MACF1 DNMBP

1.79e-05263107734702444
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

MAP2K4 KDM3B MYSM1 BRCA1 PIK3C2B MACF1 ASPSCR1 HECTD1 ZNF281

1.86e-05481107928190767
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DAB2IP DMXL2 GRIN2B KCNB2 ABLIM1 MACF1 PPP1R9B

2.73e-05281107728706196
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

NUP50 EP400 KDM3B HMGB1 DPYSL4 BAIAP2L1 FMN2 RPRD2 SRRM2

2.76e-05506107930890647
Pubmed

The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2.

HMGB1 HMGB2

2.81e-053107210490593
Pubmed

Bioinformatics analysis of the prognosis and biological significance of HMGB1, HMGB2, and HMGB3 in gastric cancer.

HMGB1 HMGB2

2.81e-053107231621076
Pubmed

A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.

MAP2K4 ELK1

2.81e-053107223582328
Pubmed

IRAK-M expression limits dendritic cell activation and proinflammatory cytokine production in response to Helicobacter pylori.

IRAK3 FOXP3

2.81e-053107223776703
Pubmed

A novel RAG1 mutation reveals a critical in vivo role for HMGB1/2 during V(D)J recombination.

HMGB1 HMGB2

2.81e-053107230538136
Pubmed

Differential association of postsynaptic signaling protein complexes in striatum and hippocampus.

GRIN2B PPP1R9B

2.81e-053107223173822
Pubmed

MicroRNA-155, induced by FOXP3 through transcriptional repression of BRCA1, is associated with tumor initiation in human breast cancer.

BRCA1 FOXP3

2.81e-053107228562349
Pubmed

High mobility group proteins stimulate DNA cleavage by apoptotic endonuclease DFF40/CAD due to HMG-box interactions with DNA.

HMGB1 HMGB2

2.81e-053107218239742
Pubmed

AFF4 regulates osteogenic potential of human periodontal ligament stem cells via mTOR-ULK1-autophagy axis.

ULK1 AFF4

2.81e-053107237731335
Pubmed

Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells.

SCRN1 SCRN2

2.81e-053107212221138
Pubmed

Identification of the core-histone-binding domains of HMG1 and HMG2.

HMGB1 HMGB2

2.81e-05310723697355
Pubmed

High mobility group proteins 1 and 2 can function as DNA-binding regulatory components for DNA-dependent protein kinase in vitro.

HMGB1 HMGB2

2.81e-05310729722660
Pubmed

Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.

AFF3 AFF4

2.81e-053107221330300
Pubmed

The kinesin superfamily protein KIF17 is regulated by the same transcription factor (NRF-1) as its cargo NR2B in neurons.

NRF1 GRIN2B

2.81e-053107221172391
Pubmed

A permissive chromatin state regulated by ZFP281-AFF3 in controlling the imprinted Meg3 polycistron.

AFF3 ZNF281

2.81e-053107228180295
Pubmed

OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy.

ABCC3 SLCO1B3

2.81e-053107230218633
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

NUP50 EP400 DIDO1 BAZ2A RPRD2 ZNF281 AFF4

2.86e-05283107730585729
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

ATXN2L KDM3B HMGB1 HMGB2 LARP4 BAIAP2L1 RPRD2 SRRM2

3.39e-05399107835987950
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B ATXN2L DIDO1 LARP4 STAU1 BAZ2A MACF1 SRRM2 HECTD1 ANKRD52

3.49e-056531071022586326
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PDS5B HMGB1 HMGB2 TTC3 NARS2 LMOD3 BRCA1 FAM186A CNKSR3 TENM1 MACF1 IRAK3 PPP1R9B ULK1 SPAG17

3.59e-0514421071535575683
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GPRASP1 DMXL2 B4GAT1 GRIN2B TTC3 MOAP1 ABLIM1 FMN2 FIP1L1 MACF1 CABIN1 HECTD1 AFF4 SPATC1L

4.07e-0512851071435914814
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

EP400 NRF1 DIDO1 STAU1 BAIAP2L1 BAZ2A FIP1L1 DNMBP

4.11e-05410107826949251
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DLG5 MYO9A BAIAP2L1 MACF1 HECTD1 TNS3

4.78e-05209107636779422
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

MYO9A HMGB1 HMGB2 STPG4 FAM186A SRRM2 TNS3 SPATC1L

4.87e-05420107828065597
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NRF1 MYO9A AFF3 LARP4 TTC3 ZNF462 STK10 ABLIM1 PTPRS MACF1 PPP1R9B RPRD2 ASPSCR1 HECTD1 AFF4

5.16e-0514891071528611215
Pubmed

Phage display screening reveals an association between germline-specific transcription factor Oct-4 and multiple cellular proteins.

HMGB1 HMGB2

5.60e-054107211099378
Pubmed

TRIM36 enhances lung adenocarcinoma radiosensitivity and inhibits tumorigenesis through promoting RAD51 ubiquitination and antagonizing hsa-miR-376a-5p.

BRCA1 TRIM36

5.60e-054107236058131
Pubmed

Physical interaction of tumour suppressor p53/p73 with CCAAT-binding transcription factor 2 (CTF2) and differential regulation of human high-mobility group 1 (HMG1) gene expression.

HMGB1 TP73

5.60e-054107212534345
Pubmed

Nup153 and Nup50 promote recruitment of 53BP1 to DNA repair foci by antagonizing BRCA1-dependent events.

NUP50 BRCA1

5.60e-054107228751496
Pubmed

The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB.

HMGB1 HMGB2

5.60e-054107214739282
Pubmed

Methylation biomarkers for pleomorphic lobular breast cancer - a short report.

BRCA1 TP73

5.60e-054107226392358
Pubmed

IRAK-M suppresses the activation of microglial NLRP3 inflammasome and GSDMD-mediated pyroptosis through inhibiting IRAK1 phosphorylation during experimental autoimmune encephalomyelitis.

GSDMD IRAK3

5.60e-054107236765034
Pubmed

A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucleoside analogues.

HMGB1 HMGB2

5.60e-054107212517784
Pubmed

Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.

AFF3 AFF4

5.60e-054107211923441
Pubmed

Knockdown of HMGB1 in tumor cells attenuates their ability to induce regulatory T cells and uncovers naturally acquired CD8 T cell-dependent antitumor immunity.

HMGB1 FOXP3

5.60e-054107221642542
Pubmed

The protein interaction landscape of the human CMGC kinase group.

NUP50 EP400 AFF3 HMGB1 DIDO1 STAU1 FIP1L1 SRRM2 ZNF281 AFF4

5.87e-056951071023602568
InteractionYWHAG interactions

MIIP DAB2IP ATXN2L DLG5 HIVEP1 ACADM ERCC6L MYO9A PSD3 KDM3B HMGB1 HMGB2 NARS2 FAM83H ABLIM1 BAIAP2L1 PIK3C2B CNKSR3 FMN2 FIP1L1 MACF1 PPP1R9B ULK1 DNMBP SRRM2 HECTD1 TNS3 KIF2C

2.06e-11124810428int:YWHAG
InteractionYWHAH interactions

MIIP DAB2IP ATXN2L DLG5 HIVEP1 ERCC6L MYO9A PSD3 KDM3B HMGB1 FAM83H ABLIM1 BAIAP2L1 PIK3C2B CNKSR3 FMN2 MACF1 PPP1R9B DNMBP SRRM2 HECTD1 TNS3 KIF2C

7.28e-09110210423int:YWHAH
InteractionCDKL5 interactions

DAB2IP ATXN2L MAP2K4 PSD3 GRIN2B KCNB2 MACF1 PPP1R9B

1.25e-071131048int:CDKL5
InteractionTERF2IP interactions

PDS5B NUP50 HIVEP1 EP400 KDM3B HMGB1 DIDO1 MYSM1 SCRN2 BRCA1 BAZ2A SRRM2 HECTD1 ZNF281 AFF4

1.53e-0755210415int:TERF2IP
InteractionMAPRE1 interactions

NUP50 DLG5 LARP4 FAM83H STAU1 IGSF10 ABLIM1 MACF1 PPP1R9B TRIM36 DNMBP SRRM2 POM121B KIF2C

4.02e-0751410414int:MAPRE1
InteractionYWHAZ interactions

MIIP DAB2IP ATXN2L DLG5 DMXL2 HIVEP1 MYO9A PSD3 HMGB1 FAM83H STAU1 ABLIM1 BRCA1 BAIAP2L1 PIK3C2B CNKSR3 MACF1 PPP1R9B C3 ULK1 DNMBP HECTD1

8.08e-07131910422int:YWHAZ
InteractionYWHAB interactions

MIIP DAB2IP ATXN2L DLG5 HIVEP1 MYO9A PSD3 HMGB1 FAM83H ABLIM1 BAIAP2L1 PIK3C2B CNKSR3 MACF1 PPP1R9B DNMBP SRRM2 HECTD1 TNS3

9.38e-07101410419int:YWHAB
InteractionPLEC interactions

ATXN2L NUP50 MYO9A MOAP1 STAU1 BRCA1 MACF1 PPP1R9B MYO18B SRRM2 SPATC1L FOXP3

2.25e-0643010412int:PLEC
InteractionSFN interactions

MIIP ATXN2L ERCC6L MYO9A HMGB1 CARD8 FAM83H ABLIM1 PIK3C2B FMN2 MACF1 DNMBP SRRM2 HECTD1 TNS3

2.62e-0669210415int:SFN
InteractionMIEN1 interactions

HIVEP1 HLX HMGB1 HMGB2

3.04e-06201044int:MIEN1
InteractionSMC5 interactions

PDS5B ATXN2L NUP50 HIVEP1 EP400 HMGB1 DIDO1 HMGB2 HMGB1P1 STAU1 BRCA1 BAZ2A FIP1L1 RPRD2 SRRM2 HECTD1 ZNF281 AFF4

3.33e-06100010418int:SMC5
InteractionYWHAQ interactions

MIIP DAB2IP ATXN2L DLG5 MYO9A PSD3 HMGB1 FAM83H STAU1 ABLIM1 BRCA1 PIK3C2B CNKSR3 MACF1 CABIN1 DNMBP HECTD1 UNC79 TNS3

3.95e-06111810419int:YWHAQ
InteractionLCOR interactions

NUP50 B4GAT1 POLR1G TTC3 MOAP1 STAU1 BAZ2A MACF1 CABIN1

4.56e-062421049int:LCOR
InteractionYWHAE interactions

MIIP DAB2IP ATXN2L DLG5 HIVEP1 MYO9A PSD3 TTC3 FAM83H ABLIM1 BRCA1 BAIAP2L1 PIK3C2B CNKSR3 MACF1 PPP1R9B ULK1 DNMBP SRRM2 HECTD1

5.63e-06125610420int:YWHAE
InteractionRAC1 interactions

DAB2IP DLG5 ATP7A PSD3 HMGB1 GRIN2B HMGB1P1 AKAP12 STAU1 STK10 BAIAP2L1 PTPRS SH3RF2 FMN2 MACF1 PPP1R9B DNMBP TNS3

7.74e-06106310418int:RAC1
InteractionSLX4 interactions

PDS5B NUP50 EP400 AFF3 KDM3B DIDO1 STAU1 ZNF462 BRCA1 RPRD2 ZNF281 AFF4 KIF2C

7.80e-0657210413int:SLX4
InteractionCAMK2D interactions

DIDO1 GRIN2B MOAP1 STAU1 SCRN2 BRCA1 PPP1R9B FOXP3

1.99e-052221048int:CAMK2D
InteractionSMARCA4 interactions

EP400 HMGB1 POLR1G TTC3 MYSM1 STAU1 BRCA1 CABIN1 SRRM2 HECTD1 FOXP3

2.68e-0546210411int:SMARCA4
InteractionSYNGAP1 interactions

DAB2IP GPRASP1 ATXN2L DMXL2 GRIN2B KCNB2 ABLIM1 PPP1R9B ULK1

3.04e-053071049int:SYNGAP1
InteractionC11orf52 interactions

DAB2IP DLG5 ATP7A PSD3 AKAP12 ABLIM1 BAIAP2L1 FMN2 MACF1

3.37e-053111049int:C11orf52
InteractionKIF2A interactions

STAU1 BRCA1 LTN1 FIP1L1 PPP1R9B TRIM36 HECTD1 KIF2C

3.68e-052421048int:KIF2A
InteractionNAA40 interactions

ATXN2L NUP50 EP400 ERCC6L KDM3B DPYSL4 DIDO1 AKAP12 STAU1 ABLIM1 BAZ2A MACF1 PPP1R9B RPRD2 ZNF281 AFF4

4.00e-0597810416int:NAA40
InteractionPOLR1G interactions

PDS5B EP400 HMGB1 HMGB2 SCRN1 POLR1G RPRD2 SRRM2 HECTD1 ZNF281 AFF4

4.49e-0548910411int:POLR1G
InteractionASF1A interactions

HIVEP1 EP400 NRF1 BRCA1 FIP1L1 CABIN1 ZNF281 TP73

4.50e-052491048int:ASF1A
InteractionCASP9 interactions

HMGB1 CARD8 HMGB1P1 AKAP12 BRCA1

4.89e-05771045int:CASP9
InteractionCDK1 interactions

DLG5 NRF1 ERCC6L HMGB1 HMGB2 AKAP12 STAU1 BRCA1 HECTD1 ZNF281 AFF4 TP73

5.28e-0559010412int:CDK1
InteractionSTXBP1 interactions

NUP50 PSD3 GRIN2B TTC3 TENM1 MACF1 PPP1R9B

6.02e-051911047int:STXBP1
InteractionCEBPA interactions

PDS5B ATXN2L NUP50 HIVEP1 EP400 TOGARAM2 KDM3B HMGB1 DIDO1 HMGB2 STAU1 STK10 BRCA1 FIP1L1 MACF1 SRRM2 ZNF281 KIF2C

6.32e-05124510418int:CEBPA
InteractionPLK1 interactions

DAB2IP ATP7A ERCC6L AKAP12 BRCA1 TRIM36 HECTD1 ANKRD52 TP73 KIF2C FOXP3

6.55e-0551010411int:PLK1
InteractionRNGTT interactions

NUP50 POLR1G BRCA1 RPRD2 SRRM2 HECTD1

7.77e-051371046int:RNGTT
InteractionLYN interactions

DAB2IP DLG5 ATP7A PSD3 KCNB2 AKAP12 STK10 ABLIM1 BAIAP2L1 FMN2 MACF1 ULK1 SRRM2

8.51e-0572010413int:LYN
InteractionKRT8 interactions

DLG5 TTC3 FAM83H LTN1 IRAK3 PPP1R9B TRIM36 DNMBP HECTD1 ANKRD52

9.49e-0544110410int:KRT8
InteractionNSD2 interactions

HMGB1 POLR1G NARS2 STAU1 BRCA1 BAZ2A HECTD1 FOXP3

9.73e-052781048int:NSD2
InteractionRHOB interactions

DAB2IP PDS5B DLG5 ATP7A MYO9A PSD3 AKAP12 TIAM2 STK10 ABLIM1 BAIAP2L1 PTPRS FMN2 MACF1

1.05e-0484010414int:RHOB
InteractionRDX interactions

NUP50 DLG5 ERCC6L STAU1 ABLIM1 BRCA1 MACF1 PPP1R9B

1.13e-042841048int:RDX
InteractionKIFC1 interactions

NUP50 POLR1G STK10 BRCA1 HECTD1

1.14e-04921045int:KIFC1
InteractionYY1 interactions

ATXN2L HIVEP1 EP400 HMGB1 DIDO1 POLR1G BRCA1 FIP1L1 CABIN1 FOXP3

1.20e-0445410410int:YY1
InteractionZC3H7A interactions

ATXN2L LARP4 TTC3 STAU1 GLE1 TRIM36 HECTD1

1.26e-042151047int:ZC3H7A
InteractionCOIL interactions

PDS5B NUP50 HIVEP1 HMGB1 HMGB2 POLR1G ZNF462 HECTD1 ZNF281 AFF4 FOXP3

1.32e-0455210411int:COIL
InteractionCIT interactions

PDS5B GPRASP1 ATXN2L NUP50 EP400 ACADM DIDO1 GRIN2B POLR1G TTC3 ABLIM1 NLRP9 BRCA1 FIP1L1 MACF1 SPAG17 SRRM2 ZNF281 KIF2C

1.42e-04145010419int:CIT
InteractionTOP3B interactions

DAB2IP ABCC3 EP400 NRF1 KDM3B LARP4 TTC3 TIAM2 FAM83H STAU1 STK10 PIK3C2B PTPRS TMEM132A PPP1R9B ULK1 CABIN1 DNMBP HECTD1

1.70e-04147010419int:TOP3B
InteractionPPIA interactions

DLG5 EP400 HMGB1 DIDO1 HMGB2 LARP4 STK10 ABLIM1 BAIAP2L1 MACF1 RPRD2 ASPSCR1 SRRM2 TNS3

1.87e-0488810414int:PPIA
InteractionTMOD1 interactions

DLG5 HLX ABLIM1 MACF1 PPP1R9B HECTD1

1.88e-041611046int:TMOD1
InteractionMAPRE3 interactions

DLG5 ABLIM1 MACF1 PPP1R9B TRIM36 DNMBP KIF2C

1.91e-042301047int:MAPRE3
InteractionUTP14A interactions

NUP50 POLR1G STAU1 PTPRS SRRM2 HECTD1 FOXP3

1.91e-042301047int:UTP14A
InteractionH3C3 interactions

PDS5B HIVEP1 KDM3B DIDO1 MYSM1 ZNF462 BRCA1 BAZ2A ZNF281 AFF4

2.42e-0449510410int:H3C3
InteractionRAD51 interactions

PDS5B EP400 BRCA1 ULK1 TRIM36 HECTD1 FOXP3

2.54e-042411047int:RAD51
InteractionOCLN interactions

DAB2IP DLG5 ATP7A PSD3 KCNB2 AKAP12 ABLIM1 FMN2 MACF1 ULK1

2.62e-0450010410int:OCLN
InteractionDYRK2 interactions

HMGB1 LARP4 MOAP1 AKAP12 FIP1L1 SRRM2

2.78e-041731046int:DYRK2
InteractionETS2 interactions

DMXL2 TTC3 BRCA1 TP73

2.79e-04611044int:ETS2
InteractionGRM1 interactions

GPRASP1 GRIN2B STAU1 CABIN1

2.97e-04621044int:GRM1
InteractionPFN1 interactions

DLG5 MYO9A ABLIM1 BRCA1 BAIAP2L1 FMN2 MACF1 DNMBP HECTD1 AFF4

3.02e-0450910410int:PFN1
InteractionMECP2 interactions

PDS5B ATXN2L NUP50 DLG5 DMXL2 EP400 HMGB1 DPYSL4 DIDO1 POLR1G STAU1 ZNF462 FIP1L1 MACF1 SRRM2 ZNF281 AFF4

3.04e-04128710417int:MECP2
InteractionKIF18B interactions

NUP50 STAU1 LTN1 KIF2C

3.35e-04641044int:KIF18B
InteractionTOPBP1 interactions

POLR1G BRCA1 HECTD1 TP73 FOXP3

3.52e-041171045int:TOPBP1
InteractionMAP1A interactions

DIDO1 GRIN2B STAU1 PPP1R9B TRIM36

3.52e-041171045int:MAP1A
InteractionGOLGA1 interactions

DLG5 ERCC6L MACF1 PPP1R9B DNMBP ANKRD52

3.75e-041831046int:GOLGA1
InteractionNOL11 interactions

NUP50 POLR1G STAU1 BRCA1 HECTD1

3.81e-041191045int:NOL11
InteractionPARP1 interactions

PDS5B HIVEP1 EP400 NRF1 HMGB1 DIDO1 HMGB2 MYSM1 STAU1 ABLIM1 BRCA1 TENM1 FIP1L1 ULK1 HECTD1 ZNF281 AFF4

3.94e-04131610417int:PARP1
InteractionCEBPB interactions

ATXN2L NUP50 ACADM NRF1 KDM3B HLX HMGB1 HMGB2 POLR1G STAU1 BRCA1 BAZ2A FIP1L1 ELK1 SRRM2 ZNF281 TNS3 KIF2C

3.97e-04144310418int:CEBPB
InteractionDIRAS3 interactions

DLG5 ATP7A PSD3 KCNB2 FMN2 MACF1 HECTD1

4.21e-042621047int:DIRAS3
InteractionCENPB interactions

BRCA1 FEZF1 HECTD1 KIF2C FOXP3

4.60e-041241045int:CENPB
InteractionSMCHD1 interactions

POLR1G NARS2 STAU1 BRCA1 HECTD1 FOXP3

4.71e-041911046int:SMCHD1
InteractionH3-3A interactions

PDS5B HIVEP1 KDM3B HMGB1 DIDO1 HMGB2 MYSM1 BRCA1 BAZ2A CABIN1 ZNF281 AFF4

4.81e-0474910412int:H3-3A
InteractionSTRAP interactions

ACADM DIDO1 STAU1 BRCA1 RPRD2 HECTD1 FOXP3

5.04e-042701047int:STRAP
InteractionCBX3 interactions

PDS5B EP400 HMGB1 HMGB2 MYSM1 ZNF462 BRCA1 BAZ2A MACF1 SRRM2 ZNF281

5.05e-0464610411int:CBX3
InteractionKAT5 interactions

EP400 LARP4 SCRN2 BRCA1 PTPRS PLA2G4A TP73 FOXP3

5.37e-043581048int:KAT5
InteractionGTF3C6 interactions

BRCA1 SRRM2 SPATC1L

5.40e-04311043int:GTF3C6
InteractionKCNA3 interactions

ATXN2L DLG5 ATP7A ERCC6L MYO9A PSD3 THSD1 AKAP12 STAU1 ABLIM1 BAIAP2L1 MACF1 KIF2C

5.41e-0487110413int:KCNA3
InteractionCDCA2 interactions

NUP50 POLR1G BRCA1 HECTD1

5.54e-04731044int:CDCA2
Cytoband12p12

SLCO1B3 GRIN2B

4.13e-0413107212p12
Cytoband6q25.2

TIAM2 CNKSR3

4.81e-041410726q25.2
CytobandEnsembl 112 genes in cytogenetic band chr6q25

TAGAP AKAP12 TIAM2 CNKSR3

6.09e-041641074chr6q25
Cytoband20q13.32

ZNF831 HMGB1P1

9.95e-0420107220q13.32
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF3 AFF4

8.08e-0546721145
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF3 AFF4

4.79e-0496721280
GeneFamilyCanonical high mobility group

HMGB1 HMGB2

7.28e-0411672511
GeneFamilyPDZ domain containing

DLG5 TIAM2 CNKSR3 PPP1R9B

2.44e-031526741220
GeneFamilyRing finger proteins

TTC3 BRCA1 SH3RF2 LTN1 TRIM36

3.52e-0327567558
CoexpressionGSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN

HIVEP1 EP400 ABLIM1 PTPRS TENM1 MACF1 AFF4 FOXP3

1.12e-061891078M3112
CoexpressionKONG_E2F3_TARGETS

NUP50 ERCC6L HLX HMGB2 BRCA1 KIF2C

2.94e-06971076MM1105
CoexpressionKONG_E2F3_TARGETS

NUP50 ERCC6L HLX HMGB2 BRCA1 KIF2C

3.51e-061001076M1157
CoexpressionGSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN

CARD8 BAZ2A TENM1 AGBL2 CABIN1 DNMBP FOXP3

1.68e-051971077M3438
CoexpressionTHILLAINADESAN_ZNF217_TARGETS_UP

NUP50 BRCA1 BAIAP2L1 CABIN1

2.37e-05411074M2197
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

DLG5 HIVEP1 ATP7A ERCC6L TAGAP MYO9A AFF3 PSD3 HMGB1 SCRN1 NARS2 ZNF462 LTN1 PLA2G4A PPP1R9B TNS3

2.61e-0682710416gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 HIVEP1 PSD3 AKAP12 MACF1 C3

5.24e-061841066d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MAP2K4 MYO9A GRIN2B KCNB2 TTC3 TENM1

6.69e-0619210664c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERCC6L HMGB1 HMGB2 BRCA1 TP73 KIF2C

8.44e-06200106663f9481059be608ddc9fe9c7a8f8503fce9755dd
ToppCellsevere_influenza-CD8+_T_naive|World / disease group, cell group and cell class (v2)

PSD PSD3 THSD1 LMOD3 KIF2C

4.05e-051601065a1181ef36b453eba53b04d836aa9f65a71354cdb
ToppCellsevere_influenza-CD8+_T_naive|severe_influenza / disease group, cell group and cell class (v2)

PSD PSD3 THSD1 LMOD3 KIF2C

4.17e-05161106582196139cdbbd70a36957a87bc9ac6d02575da3f
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ERCC6L SLCO1B3 HMGB2 BRCA1 KIF2C

4.43e-0516310655285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2K4 NARS2 PPP1R9B DNMBP SPATC1L

4.97e-051671065961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP2K4 NARS2 PPP1R9B DNMBP SPATC1L

4.97e-0516710653760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

BRCA1 CNKSR3 PITX3 SPATC1L

5.09e-05851064159b3ac93490c3e4918ea61f8ede7add9e63ca40
ToppCellmetastatic_Brain-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

HIVEP1 AFF3 PTPRS CNKSR3 KIF2C

5.11e-0516810654bf3f85aac4b335efa93d22c9ce7b153cb5ce152
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PSD3 TIAM2 FAM83H TMEM132A MYO18B

5.41e-051701065513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

PSD DPYSL4 KCNB2 FMN2 UNC79

6.20e-0517510654db1a3c284488b3f6de7568363f176d74e2a4587
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7A STK10 PIK3C2B IRAK3 C3

6.20e-051751065cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

PSD DPYSL4 KCNB2 FMN2 UNC79

6.20e-0517510658d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMXL2 POLR1G SH3RF2 PPP1R9B ANKRD52

6.55e-051771065e1e45956887371b1c18f1eb479dd930031497520
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AFF3 AKAP12 LMOD3 PLA2G4A IRAK3

6.55e-051771065b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DLG5 ABLIM1 MACF1 ULK1 AFF4

6.90e-0517910656e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL4 IGSF10 BRCA1 PTPRS CNKSR3

7.27e-0518110654e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL4 IGSF10 BRCA1 PTPRS CNKSR3

7.27e-051811065ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL4 IGSF10 BRCA1 PTPRS CNKSR3

7.27e-0518110653a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

TOGARAM2 FMN2 AGBL2 SPAG17 TP73

8.06e-05185106530f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

GRIN2B FAM186A IRAK3 PPP1R9B SPAG17

8.27e-05186106523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSD GRIN2B ZNF831 TTC3 GNG3

8.48e-051871065e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSD GRIN2B ZNF831 TTC3 GNG3

8.48e-05187106524cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSD GRIN2B ZNF831 TTC3 GNG3

8.48e-0518710652f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

TOGARAM2 FMN2 AGBL2 SPAG17 TP73

8.70e-05188106561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERCC6L HMGB1 HMGB2 TP73 KIF2C

8.92e-051891065fd8834d1feb7f63911c5fa51efb1f679a8baddeb
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GPRASP1 PSD GRIN2B TTC3 TENM1

9.14e-051901065416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellILEUM-non-inflamed-(8)_Activated_fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ABCC3 B4GAT1 POLR1G ZNF462 TMEM132A

9.14e-05190106539fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T|bone_marrow / Manually curated celltypes from each tissue

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

9.37e-051911065210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

HMGB2 POLR1G ULK1 SRRM2 KIF2C

9.60e-0519210659cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCelldroplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIIP ERCC6L HMGB1 HMGB2 KIF2C

9.60e-05192106596f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 PSD3 AKAP12 STK10 MACF1

9.60e-0519210658b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

ABCC3 DMXL2 STK10 IRAK3 TNS3

9.84e-051931065cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPRASP1 HIVEP1 EP400 TAGAP MACF1

1.01e-0419410653211d89440a6f4a9b3d4cfb755890816944242ec
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L HMGB2 BRCA1 TP73 KIF2C

1.01e-0419410651a2090e997c70433d07f56bf7cb0a50c4151118c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L HMGB2 BRCA1 TP73 KIF2C

1.03e-04195106575759fd7f925725f0ecd07214afcca5aa2158f9e
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC3 FMN2 MACF1 SRRM2 AFF4

1.03e-0419510653e519cffa6144a62b06124642a14c9ff39b76554
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 AFF3 HLX SCRN1 TNS3

1.03e-041951065cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCC3 DMXL2 IRAK3 PPP1R9B SRRM2

1.06e-04196106589ff93cbfbe39fbdf2498e8fdc5d61a0ecb26fc9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.06e-0419610651964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCC3 DMXL2 IRAK3 PPP1R9B SRRM2

1.06e-04196106509574bfeb1d3da53b5471cfb0602946d328b3b5c
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

MIIP ATXN2L TTC3 SRRM2 AFF4

1.06e-0419610657bced0cc2112697593c478fa291b8ed3941fb811
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.06e-04196106573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MYO9A ABLIM1 BAIAP2L1 TNS3

1.08e-0419710657e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ABCC3 AFF3 IGSF10 MACF1 IRAK3

1.08e-0419710650034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.08e-04197106547be19f595135da248469b2e21b8d88f561827b2
ToppCellCOVID-19_Severe-CD4+_T_naive|COVID-19_Severe / Disease condition and Cell class

GPRASP1 HIVEP1 TTC3 AKAP12 ABLIM1

1.08e-041971065ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCellTransverse-T_cell-cycling_gd_T|Transverse / Region, Cell class and subclass

ERCC6L DPYSL4 FAM83H BRCA1 KIF2C

1.11e-0419810655131b0b7d6c4dd8872cef9f2e233f59f751b4690
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AFF3 GRIN2B TTC3 FMN2 UNC79

1.11e-041981065c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.11e-041981065d484ac79d6cd29f1d9c192d126c2099f737d5320
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AFF3 GRIN2B TTC3 FMN2 UNC79

1.11e-0419810656d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellnormal_Lung-T/NK_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.11e-041981065c65cdb54409087014125a76627e5efb5fe8dabc9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Cycling_Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.11e-041981065ac0be1666456cfa8d68588b187d65008e6d5c0e2
ToppCellTransverse-(1)_T_cell-(18)_cycling_gd_T|Transverse / shred on region, Cell_type, and subtype

ERCC6L DPYSL4 FAM83H BRCA1 KIF2C

1.11e-041981065396dddf7ebad41c3a91329b6a280623c0dfdcd2f
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.11e-04198106548d39018c56ea8ba972c72af8ece10cbeb48fbc8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AFF3 GRIN2B KCNB2 TTC3 UNC79

1.11e-0419810650ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell(5)_Dendritic_cell-(52)_cycling_DCs|(5)_Dendritic_cell / shred on Cell_type and subtype

DMXL2 HMGB1 HMGB2 BRCA1 KIF2C

1.14e-041991065d0ff446a197062b10f37b585f3f8716d6d89e5b7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.14e-0419910654af38f5e9d2229d64f7ecdf9c00b4d67e5f86a51
ToppCellnormal_Lung-T/NK_cells-Undetermined|T/NK_cells / Location, Cell class and cell subclass

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.14e-0419910654142d5b1b20212508f95841fdac4efb7655616cb
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

DLG5 CPEB3 PSD3 PTPRS SH3RF2

1.16e-042001065682960e28542a3d6c119047cd0131941932cfdea
ToppCellNS-moderate-d_07-13-Lymphoid-NKT-proliferating|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.16e-04200106587e293c0882e2754756a2210a6c04723dc89f81b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.16e-04200106528c702449040ac15fe4e0c6340bb6f137e88539d
ToppCellmild-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ABCC3 DMXL2 SCRN1 IRAK3 C3

1.16e-042001065334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCellNon-neuronal-Dividing-IPC-IPC-div2|World / Primary Cells by Cluster

HMGB1 HMGB2 SCRN1 IGSF10 BRCA1

1.16e-0420010654923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCellNon-neuronal-Dividing-IPC-IPC-div2-5|World / Primary Cells by Cluster

HMGB1 HMGB2 SCRN1 IGSF10 BRCA1

1.16e-042001065dc1c1506823eaa105f1532c6b5d4efa14e788314
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Cortical_neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

GRIN2B TTC3 TENM1 GNG3 TRIM36

1.16e-04200106568c90376e2779434e4ad8dc6dd3b44baa700e2f4
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.16e-0420010657e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

ERCC6L HMGB1 HMGB2 BRCA1 KIF2C

1.16e-0420010659775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLG5 PSD3 SH3RF2 FOXP3

3.13e-0413610647cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-2|TCGA-Bladder / Sample_Type by Project: Shred V9

PSD AFF3 IGSF10 LMOD3

3.58e-0414110641baa054c2ae3b446d1954244b7fbf8af824ef345
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Etv1_(Deep_layer_pyramidal_cells-Etv1_typically_marks_layer_5b,_but_some_expression_in_layer_6,_especially_in_medial_regions_like_cingulate)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

LRRC72 MOAP1 FEZF1

3.94e-04601063f20230c11a2ca2f66650e53ea6eaa301402294c0
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Etv1_(Deep_layer_pyramidal_cells-Etv1_typically_marks_layer_5b,_but_some_expression_in_layer_6,_especially_in_medial_regions_like_cingulate)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

LRRC72 MOAP1 FEZF1

3.94e-0460106371e2aa3da41319c72b4eac30e54c65e65e62a3d9
ToppCellCOVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class

DLG5 TOGARAM2 SH3RF2 MACF1

4.20e-041471064baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

GPRASP1 LMOD3 ANKRD52 FOXP3

4.30e-04148106480470353e12599440f711b6e107730763376d04d
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MOAP1 PITX3 FOXP3

4.35e-0462106391c49ae176d2a418a58398e9d5e55c77187cc2fb
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Crim1_(Neuron.Gad1Gad2.Cplx3-Crim1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MOAP1 PITX3 FOXP3

4.35e-046210633275775572a65460b6248ee72b4c85e4d4dee424
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DAB2IP LRRC72 HLX STK10

5.12e-04155106459035d792c26d870a8b097939e97fa47859ba68c
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

BAIAP2L1 PLA2G4A DNMBP SRRM2

5.64e-041591064655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

GPRASP1 AFF3 IGSF10 LMOD3

5.77e-0416010648a41e2c96e0e170ac35daf6c403bf961b8d7c30b
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TAGAP HMGB2 SCRN2 FOXP3

5.77e-0416010648308ca6f37986c526432a0fbc5f7ec2e75cfb6d7
ToppCellTCGA-Bladder-Solid_Tissue_Normal|TCGA-Bladder / Sample_Type by Project: Shred V9

GPRASP1 AFF3 IGSF10 LMOD3

5.77e-041601064d6678996e12eaf2b735f1dfae32418cb2fabf268
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue|TCGA-Bladder / Sample_Type by Project: Shred V9

GPRASP1 AFF3 IGSF10 LMOD3

5.77e-041601064c8dc575562b463fd30832d322c28006f18f7ab9c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AFF3 TOGARAM2 PTPRS PLA2G4A

6.05e-0416210649dca585c734faea0e1122c70f5dc36cef3dbd2c6
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

TOGARAM2 AGBL2 SPAG17 TP73

6.33e-0416410640e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MYO9A TENM1 C3

6.33e-0416410641cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

GRIN2B THSD1 AKAP12 CNKSR3

6.63e-0416610645ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6L KDM3B ZNF831 ABLIM1

6.63e-0416610646a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERCC6L KDM3B ZNF831 ABLIM1

6.63e-0416610648d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

GRIN2B THSD1 AKAP12 CNKSR3

6.63e-0416610646bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

AFF3 SCRN1 PLA2G4A IRAK3

6.63e-041661064773673a5d0430640439845b264740bfbbdad0cb2
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DPYSL4 GRIN2B ZNF831 AKAP12

6.63e-041661064c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell367C-Myeloid-Dendritic-pDC|367C / Donor, Lineage, Cell class and subclass (all cells)

HIVEP1 AFF3 SCRN1 PTPRS

6.78e-041671064650de8cd5df070639b8aa292aacead739cfdb02c
ToppCellThalamus-Macroglia-POLYDENDROCYTE|Thalamus / BrainAtlas - Mouse McCarroll V32

BRCA1 FAM186A CNKSR3 ZNF281

6.78e-0416710641e144c03409df94ccd39760842590e8ea7487e29
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like|GI_small-bowel / Manually curated celltypes from each tissue

AFF3 SCRN1 PLA2G4A IRAK3

6.78e-0416710643ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPYSL4 LMOD3 FEZF1 DIO2

6.78e-041671064805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPYSL4 LMOD3 FEZF1 DIO2

6.78e-04167106431cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPYSL4 LMOD3 FEZF1 DIO2

6.78e-0416710643acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

GPRASP1 AKAP12 ZNF462 TRIM36

6.93e-04168106445ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|368C / Donor, Lineage, Cell class and subclass (all cells)

GRIN2B THSD1 AKAP12 CNKSR3

6.93e-041681064a74c8a9e3299183fba31ce3053ef325b5dbcd104
DrugProbucol [23288-49-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

MIIP ATXN2L DLG5 DPYSL4 THSD1 CARD8 BRCA1 SRRM2

4.29e-0619910683223_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

PDS5B DLG5 KDM3B DIDO1 BAZ2A CABIN1 SRRM2

2.09e-0517910676609_DN
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A

PDS5B EP400 PSD3 ABLIM1 BRCA1 MACF1 ASPSCR1

3.50e-0519410671670_DN
Druggenistein; Up 200; 10uM; MCF7; HT_HG-U133A_EA

ATXN2L NRF1 THSD1 BAZ2A PTPRS GLE1 CABIN1

3.62e-0519510671015_UP
DrugMefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A

NRF1 DIDO1 BRCA1 BAZ2A RPRD2 CABIN1 DNMBP

3.74e-0519610671821_DN
DrugFluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A

MIIP PDS5B AKAP12 BAZ2A ELK1 ASPSCR1 AFF4

3.86e-0519710676219_UP
DrugJosamycin [16846-24-5]; Down 200; 4.8uM; HL60; HG-U133A

PIK3C2B BAZ2A MACF1 IRAK3 RPRD2 ELK1 CABIN1

3.86e-0519710672034_DN
DrugMegestrol acetate [595-33-5]; Down 200; 10.4uM; MCF7; HT_HG-U133A

NRF1 CPEB3 PSD3 PIK3C2B ASPSCR1 CABIN1 TNS3

3.99e-0519810675013_DN
DrugMelatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A

MIIP ATXN2L ABCC3 DLG5 NRF1 PSD3 PTPRS

3.99e-0519810675393_DN
DrugHomatropine hydrobromide (R,S) [51-56-9]; Up 200; 11.2uM; PC3; HT_HG-U133A

ABCC3 EP400 LARP4 GLE1 ELK1 ASPSCR1 CABIN1

3.99e-0519810671806_UP
DrugTropicamide [1508-75-4]; Down 200; 14uM; HL60; HT_HG-U133A

MIIP NRF1 DIDO1 LARP4 PIK3C2B BAZ2A MACF1

4.12e-0519910672347_DN
DiseaseX-24588 measurement

ABCC3 SLCO1B3 DNMBP

1.22e-05131053EFO_0800898
Diseasecolorectal cancer (is_marker_for)

DAB2IP ERCC6L KDM3B BRCA1 AFF4 KIF2C

2.15e-051571056DOID:9256 (is_marker_for)
DiseaseX-21441 measurement

ABCC3 SLCO1B3 DNMBP

2.87e-05171053EFO_0800814
DiseaseAlzheimer disease, educational attainment

ATXN2L PSD AFF3 STAU1 PIK3C2B PITX3 TRIM36

3.00e-052471057EFO_0011015, MONDO_0004975
Diseaseintelligence, self reported educational attainment

ATXN2L AFF3 STAU1 PITX3 TRIM36

6.33e-051171055EFO_0004337, EFO_0004784
Diseasebody fat percentage

PDS5B ATXN2L DMXL2 HIVEP1 HMGB1 KCNB2 MACF1 AGBL2 UNC79

6.35e-054881059EFO_0007800
DiseaseMalignant neoplasm of breast

MAP2K4 B4GAT1 ACADM TTC3 AKAP12 NLRP9 BRCA1 TENM1 PLA2G4A MACF1 ZNF281 TP73 FOXP3

1.15e-04107410513C0006142
DiseaseNeurologic Symptoms

ATP7A PITX3

1.25e-0451052C0235031
DiseaseNeurological observations

ATP7A PITX3

1.25e-0451052C0422837
DiseaseNeurologic Manifestations

ATP7A PITX3

1.25e-0451052C0027854
DiseaseNeurologic Dysfunction

ATP7A PITX3

1.25e-0451052C0751377
DiseaseNeurologic Signs

ATP7A PITX3

1.25e-0451052C0751378
DiseaseFocal Neurologic Deficits

ATP7A PITX3

1.25e-0451052C0746857
DiseaseNeurologic Deficits

ATP7A PITX3

1.86e-0461052C0521654
Diseasebreast ductal carcinoma (is_marker_for)

SLCO1B3 TP73

3.46e-0481052DOID:3007 (is_marker_for)
DiseaseRheumatoid Arthritis

ABCC3 TAGAP AFF3 BAIAP2L1 FOXP3

4.04e-041741055C0003873
Diseasetropical spastic paraparesis (is_marker_for)

C3 FOXP3

4.44e-0491052DOID:321 (is_marker_for)
DiseaseX-21467 measurement

SLCO1B3 DNMBP

4.44e-0491052EFO_0020007
Diseasealcohol use disorder (implicated_via_orthology)

PSD PSD3 KDM3B SRRM2 UNC79

6.77e-041951055DOID:1574 (implicated_via_orthology)
Diseasehepatocellular carcinoma (is_marker_for)

DAB2IP MAP2K4 SLCO1B3 PPP1R9B TP73 FOXP3

7.41e-043011056DOID:684 (is_marker_for)
Diseasemetabolite measurement

ABCC3 ACADM PSD3 HMGB1 ZNF462 STK10 CABIN1 DNMBP

8.92e-045601058EFO_0004725
Diseasecolorectal cancer (is_implicated_in)

MAP2K4 BRCA1 TP73 FOXP3

9.35e-041211054DOID:9256 (is_implicated_in)
DiseaseAlzheimer disease, cognitive decline measurement, Cognitive impairment

PDS5B TIAM2

9.54e-04131052EFO_0007710, HP_0100543, MONDO_0004975
DiseaseBenign tumor of pancreas

MAP2K4 BRCA1

9.54e-04131052C0347284
Diseaseglycochenodeoxycholate glucuronide (1) measurement

ABCC3 SLCO1B3

9.54e-04131052EFO_0800474
DiseaseSeizures

ATP7A AFF3 KDM3B NARS2 MACF1

1.12e-032181055C0036572
Diseaseneutrophil count

HIVEP1 SPATA6L TAGAP PSD3 HLX AKAP12 BRCA1 BAIAP2L1 FAM186A CNKSR3 RPRD2 AGBL2 TNS3

1.26e-03138210513EFO_0004833
Diseasenasopharynx carcinoma (is_implicated_in)

MAP2K4 BRCA1

1.28e-03151052DOID:9261 (is_implicated_in)
Diseasevisceral adipose tissue measurement

HMGB1 KCNB2 STPG4 PIK3C2B AGBL2 UNC79 TP73

1.69e-034811057EFO_0004765
Diseasecognitive function measurement

ATXN2L DMXL2 MAP2K4 HIVEP1 LINC00052 AFF3 PSD3 GRIN2B STAU1 CNKSR3 DIO2 MYO18B TRIM36

1.74e-03143410513EFO_0008354
Diseasetestosterone measurement

ATXN2L ERCC6L PSD3 SLCO1B3 POLR1G LARP4 BAIAP2L1 FAM186A CNKSR3 MACF1 DNMBP TNS3

1.94e-03127510512EFO_0004908
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

PDS5B ATXN2L HIVEP1 KCNB2 MACF1 UNC79

1.95e-033641056EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseaseforced expiratory volume

ATXN2L AFF3 PSD3 HLX PIK3C2B ERCC6L2 DIO2 RPRD2 ASPSCR1

2.04e-037891059EFO_0004314
DiseasePancreatic carcinoma

MAP2K4 BRCA1

2.06e-03191052C0235974
Diseaseresponse to methotrexate, neurotoxicity

DAB2IP MACF1

2.06e-03191052EFO_0011057, GO_0031427
Diseasebody surface area

HIVEP1 DIDO1 KCNB2 TIAM2 ZNF462 FEZF1 MACF1 UNC79

2.13e-036431058EFO_0022196
Diseaselung cancer (is_implicated_in)

DAB2IP MAP2K4 TP73

2.36e-03741053DOID:1324 (is_implicated_in)
DiseaseImmunologic Deficiency Syndromes

MYSM1 C3

3.02e-03231052C0021051
Diseasechronic widespread pain

MAP2K4 LARP4

3.02e-03231052EFO_0010099
DiseaseHuntington's disease (is_implicated_in)

NRF1 GRIN2B

3.02e-03231052DOID:12858 (is_implicated_in)
DiseaseBreast Carcinoma

MAP2K4 B4GAT1 AKAP12 BRCA1 PLA2G4A TP73 FOXP3

3.16e-035381057C0678222
Diseasethyroxine measurement

DIDO1 DIO2 AGBL2

3.27e-03831053EFO_0005130
Diseasecoronary artery disease

DAB2IP PDS5B PSD3 KCNB2 ZNF831 AKAP12 IGSF10 FMN2 RPRD2 CABIN1 TNS3

3.52e-03119410511EFO_0001645

Protein segments in the cluster

PeptideGeneStartEntry
PTKFPFPNKDSQLVS

AFF3

326

P51826
PPIATFSANPEAKAA

EP400

1506

Q96L91
KQSTRAPAAAPFVPF

ASPSCR1

231

Q9BZE9
APRSPAKLSFQFPSS

ELK1

386

P19419
KFSKFPAAQAPDPSE

ABLIM1

546

O14639
FEFFPPSPRSVDQVK

B4GAT1

46

O43505
AQKERPPAPSSFVFQ

AKAP12

1216

Q02952
PAAAFPTASPANKDV

BAZ2A

501

Q9UIF9
LFPDKKQRTFQPPAT

GSDMD

231

P57764
QPSSAFAAFVKRAPS

C3

1061

P01024
TFFPESLPATKKPFE

DNMBP

1236

Q6XZF7
QPSFVPKSPDASSAF

GLE1

81

Q53GS7
PENTPFKSRDSSAFP

DMXL2

2596

Q8TDJ6
RSDPDPKAPANKAFT

ACADM

206

P11310
FPPKDAVSPFSFSLL

ANKRD52

1021

Q8NB46
RKFGAQFKLQPSSSP

ATXN2L

546

Q8WWM7
EPSKFPFPTKESQQS

AFF4

341

Q9UHB7
ERAKVNPITFFDTPP

ATP7A

771

Q04656
SAPPFASAKAAADPK

NUP50

96

Q9UKX7
LNFANPPFKSTARFT

MAP2K4

46

P45985
ESPKDPVLPARFFTQ

PDS5B

1086

Q9NTI5
REKPPFFSAKNVDPN

ABCC3

191

O15438
AKDAFEAAFPPSKQP

LTN1

166

O94822
EAAFPPSKQPEAIAF

LTN1

171

O94822
PSPTPENKDLFFVTR

DAB2IP

701

Q5VWQ8
ATUPPFTSQLPAFRK

DIO2

131

Q92813
DPNAPKRPPSAFFLF

HMGB1

91

P09429
SFPLDPAAVKKPSFC

HLX

31

Q14774
FPNPSAPRKDSTLSA

FOXP3

171

Q9BZS1
KPSQAPKYRTDPDSF

LMOD3

471

Q0VAK6
DPNAPKRPPSAFFLF

HMGB2

91

P26583
CFVSRPHPKPKQFSS

DDX58

841

O95786
VIFKPPDPDNTFLSR

MOAP1

91

Q96BY2
ATEVDNNFSKPPPFF

FIP1L1

346

Q6UN15
SPSKPNPVFKVFGAA

NRF1

136

Q16656
KSIFDPNTFKRPQTP

DLG5

971

Q8TDM6
PKLSREEPSNPFLAF

KDM3B

626

Q7LBC6
PFSPRTAEFKSRQPA

MACF1

576

O94854
TPVPTSENPFREKKF

GNG3

56

P63215
SFLDKKVPPCPRNFS

IRAK3

401

Q9Y616
QKSEPTFAASPFSDP

PTPRS

1251

Q13332
DIKFTSPPGDKFSPR

PIK3C2B

791

O00750
ATSAPSPAPKQSFLF

POM121B

276

A6NF01
SKRAFKQSPPAVPAL

TP73

326

O15350
FKVSKRQSFAPFSNP

BRCA1

861

P38398
AKAAAFVTSPPVNPD

DPYSL4

296

O14531
QPQFTFPPDEFTSKK

HECTD1

2026

Q9ULT8
FPSAAPITFPKADIA

IGSF10

1081

Q6WRI0
PRFPKQKLFPFSSRE

KCNB2

786

Q92953
TFKAPASKPETAAPN

BAIAP2L1

461

Q9UHR4
TTPKHPKDSRENFFP

CABIN1

1926

Q9Y6J0
FSSNVIAPPKFPRAA

CPEB3

296

Q8NE35
ETPKPNFSKTSRPEF

GFY

151

I3L273
AASAPPPFSGAAFVK

CARD8

441

Q9Y2G2
PAPRNLVPKKSSFAN

DIDO1

561

Q9BTC0
PPRFKDSPASAFRVA

AGBL2

116

Q5U5Z8
KAPTPKFDLLASNFP

LARP4

471

Q71RC2
TTERFPDNSIRFKPP

ERCC6L2

921

Q5T890
PSAPDFKVAQVPFTT

FAM186A

1971

A6NE01
LPSAFRVPAAFPTKV

FAM83H

626

Q6ZRV2
QPAAKDSPSSTAFPF

FMN2

311

Q9NZ56
DRSPSPSKNDSFFTP

RPRD2

926

Q5VT52
AANSRKQFSVPPAPT

KIF2C

136

Q99661
LAPPLAAKTFPFAFN

PITX3

161

O75364
ASTPKNDISPPGRFF

ERCC6L

1061

Q2NKX8
SPFKQKPAQRVPSDF

LRRC72

211

A6NJI9
FSARPSDSSPPFKEL

PLA2G4A

576

P47712
GFPSISPFRFPKEAA

GPRASP1

1061

Q5JY77
NTRDFLFPEPKLTPS

SPATA6L

86

Q8N4H0
QKFFIPKSPTSSNEP

TRIM36

641

Q9NQ86
ATASPPRQKDKFSPF

SRRM2

1176

Q9UQ35
KFSPFPVQDRPESSL

SRRM2

1186

Q9UQ35
FSAPPFPAAVSSQKK

PSD

871

A5PKW4
FPAAVSSQKKFSRPL

PSD

876

A5PKW4
SSPVASPSSPKRNFF

TAGAP

471

Q8N103
KRVEFVTFAPAPPAQ

TMEM132A

961

Q24JP5
AAAKKPALPFSQSAP

TOGARAM2

306

Q6ZUX3
VRFCSSAPFPKHKPS

NARS2

11

Q96I59
TATPDPSRSVFKPFI

SCRN2

306

Q96FV2
SDFSRGSPNAKPKVF

FEZF1

246

A0PJY2
DPNAPKRPPSAFFLF

HMGB1P1

91

B2RPK0
DIFPPKSEKSSAPRN

MIIP

321

Q5JXC2
PNFTAKPPASESPRF

POLR1G

16

O15446
PRSTFSRPAFTFNKP

TENM1

296

Q9UKZ4
PSKAFKPRFPGDQVV

TNS3

661

Q68CZ2
SIPFPNVLPDFSKAS

TNS3

1131

Q68CZ2
CAAPSQAPFKAFLSP

SPATC1L

106

Q9H0A9
GTPDPSRSIFKPFIF

SCRN1

296

Q12765
DFCRFKVKQPPPSTG

SPAG17

2106

Q6Q759
KRPTGSFNFTPAPLK

CNK3/IPCEF1

291

G9CGD6
KRPTGSFNFTPAPLK

CNKSR3

291

Q6P9H4
FKAGSQSFPPKVNRA

NLRP9

376

Q7RTR0
TCVFTFKAAPSPRPA

LINC00052

121

Q96N35
FPPGDAKKPFNQSSS

TIAM2

281

Q8IVF5
TKDFTRAAPNPAKAT

STAU1

436

O95793
QVATYSFKDKPRPSP

STPG4

111

Q8N801
AANKFRIKSPFPEQP

THSD1

581

Q9NS62
ISSIPFFFLPKNPNK

SLCO1B3

271

Q9NPD5
ECPNPSTPSKAAKFF

STK10

946

O94804
SSSAPAFENVKPKPV

TTC3

1226

P53804
AFENVKPKPVSANSP

TTC3

1231

P53804
KKEPAASAAAFPSQR

ZNF281

101

Q9Y2X9
FDDFLPAIRKPQTPT

MYO18B

2441

Q8IUG5
PATFNKNTPKTFTPE

ZNF462

1001

Q96JM2
PRQSRPFKSVFVPTA

SH3RF2

476

Q8TEC5
PKPYIFSDAQRPSSF

ZNF831

1461

Q5JPB2
SAPPFPAAIGSQKKF

PSD3

901

Q9NYI0
SLSRPNSFDKPEPFE

HIVEP1

1141

P15822
KAVPSFDFPKTPSSQ

ULK1

626

O75385
SPLRSPFRSPFKNFG

UNC79

766

Q9P2D8
FPSPKISSSPKFDSR

MYO9A

1356

B2RTY4
LKVPRPTKSSFDPFQ

MYSM1

546

Q5VVJ2
VSRFDSKPAPSAQPA

PPP1R9B

121

Q96SB3
LSDKKFQRPNDFSPP

GRIN2B

666

Q13224