Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HMCN1 LAMA5 LAMB1 EMILIN3 SSPOP AGRN TNXB FBN3

9.51e-07188818GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

SNED1 TRPM4 SCUBE1 CELSR1 ARSA HMCN1 MEGF8 ADAMTS13 AGRN FBN3 LRP8

2.13e-047498111GO:0005509
GeneOntologyMolecularFunctionextracellular matrix binding

SSC5D ADAMTSL5 AGRN TNXB

2.21e-0473814GO:0050840
GeneOntologyMolecularFunctionnodal binding

CFC1 CFC1B

4.48e-048812GO:0038100
GeneOntologyMolecularFunctionintegrin binding

CCN5 LAMA5 LAMB1 ADAMTS13 TNXB

7.31e-04175815GO:0005178
GeneOntologyCellularComponentextracellular matrix

CCN5 SNED1 SSC5D HMCN1 ADAMTSL5 LAMA5 LAMB1 EMILIN3 ADAMTS13 SSPOP AGRN ADAMTSL4 TNXB IGFBPL1 FBN3

2.41e-086568015GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

CCN5 SNED1 SSC5D HMCN1 ADAMTSL5 LAMA5 LAMB1 EMILIN3 ADAMTS13 SSPOP AGRN ADAMTSL4 TNXB IGFBPL1 FBN3

2.51e-086588015GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

SSC5D HMCN1 ADAMTSL5 LAMA5 LAMB1 EMILIN3 SSPOP AGRN ADAMTSL4 TNXB IGFBPL1

5.41e-065308011GO:0062023
GeneOntologyCellularComponentlaminin-10 complex

LAMA5 LAMB1

4.33e-053802GO:0043259
GeneOntologyCellularComponentLUBAC complex

RNF31 RBCK1

8.64e-054802GO:0071797
GeneOntologyCellularComponentsynaptic cleft

CBLN2 LAMA5 AGRN

2.71e-0433803GO:0043083
GeneOntologyCellularComponentlaminin complex

LAMA5 LAMB1

6.38e-0410802GO:0043256
GeneOntologyCellularComponentmicrofibril

ADAMTSL5 FBN3

1.10e-0313802GO:0001527
GeneOntologyCellularComponentbasement membrane

HMCN1 LAMA5 LAMB1 AGRN

1.24e-03122804GO:0005604
GeneOntologyCellularComponentendoplasmic reticulum lumen

ARSA LAMB1 SDF2L1 ADAMTS13 ADAMTSL4 ANO8

1.72e-03332806GO:0005788
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMB1 TNXB

1.90e-0317802GO:0098637
GeneOntologyCellularComponentubiquitin ligase complex

FBXO24 RNF31 MEGF8 KCTD5 FBXL19 RBCK1

2.31e-03352806GO:0000151
MousePhenoabnormal direction of embryo turning

MEGF8 PKD1L1 CFC1 CFC1B

3.76e-0713694MP:0004190
MousePhenomesocardia

MEGF8 CFC1 LAMA5 CFC1B

2.48e-0620694MP:0000650
MousePhenoright pulmonary isomerism

MEGF8 PKD1L1 CFC1 CFC1B

6.36e-0625694MP:0000531
MousePhenoabnormal lung position or orientation

MEGF8 PKD1L1 CFC1 LAMA5 CFC1B

8.68e-0657695MP:0010853
MousePhenoaccessory spleen

MEGF8 CFC1 CFC1B

9.47e-069693MP:0003342
MousePhenoabnormal left lung morphology

MEGF8 PKD1L1 CFC1 CFC1B

1.02e-0528694MP:0009569
MousePhenoright-sided isomerism

MEGF8 PKD1L1 CFC1 CFC1B

1.35e-0530694MP:0000508
MousePhenoright-sided stomach

MEGF8 PKD1L1 CFC1 CFC1B

1.55e-0531694MP:0010808
MousePhenototal anomalous pulmonary venous connection, intracardiac

CFC1 CFC1B

2.40e-052692MP:0010443
MousePhenoabnormal stomach position or orientation

MEGF8 PKD1L1 CFC1 CFC1B

2.84e-0536694MP:0010807
MousePhenoabnormal heart position or orientation

MEGF8 PKD1L1 CFC1 LAMA5 CFC1B

3.13e-0574695MP:0006065
MousePhenod-loop transposition of the great arteries

MEGF8 CFC1 CFC1B

3.18e-0513693MP:0011665
MousePhenoanomalous pulmonary venous connection

MEGF8 CFC1 CFC1B

5.02e-0515693MP:0010440
MousePhenoabnormal sperm midpiece morphology

FBXO24 DDHD1 TYSND1 RXRB TULP2 LRP8

7.57e-05144696MP:0009831
MousePhenoheterotaxia

MEGF8 PKD1L1 CFC1 LAMA5 CFC1B

8.03e-0590695MP:0004133
MousePhenoabnormal sperm flagellum morphology

FBXO24 ARSA EGR4 DDHD1 TYSND1 RXRB TULP2 LRP8

9.79e-05295698MP:0008892
MousePhenoabnormal sperm mitochondrial sheath morphology

FBXO24 DDHD1 TYSND1 RXRB LRP8

1.04e-0495695MP:0009832
MousePhenodextrocardia

MEGF8 PKD1L1 CFC1 CFC1B

1.14e-0451694MP:0000644
MousePhenounbalanced complete common atrioventricular canal

CFC1 CFC1B

1.43e-044692MP:0011673
MousePhenototal anomalous pulmonary venous connection

CFC1 CFC1B

1.43e-044692MP:0010441
MousePhenokinked sperm flagellum

EGR4 DDHD1 TULP2 LRP8

1.65e-0456694MP:0009237
MousePhenoabnormal digestive organ placement

MEGF8 PKD1L1 CFC1 CFC1B

1.76e-0457694MP:0003283
MousePhenositus inversus

MEGF8 PKD1L1 CFC1 CFC1B

2.15e-0460694MP:0002766
MousePhenoright aortic arch

MEGF8 CFC1 LAMA5 CFC1B

2.15e-0460694MP:0004158
MousePhenoabnormal eyelid margin morphology

EDA HR

2.38e-045692MP:0013745
MousePhenocoiled sperm flagellum

ARSA EGR4 RXRB LRP8

2.44e-0462694MP:0009238
MousePhenoabnormal cilium morphology

CELSR1 FBXO24 ARSA EGR4 DDHD1 TYSND1 RXRB TULP2 LRP8

2.64e-04433699MP:0013202
MousePhenocomplete atrioventricular septal defect

MEGF8 CFC1 CFC1B

2.76e-0426693MP:0010413
MousePhenoabnormal hair follicle dermal papilla morphology

LAMA5 HR

3.56e-046692MP:0003813
MousePhenoabsent spleen

MEGF8 CFC1 CFC1B

3.84e-0429693MP:0000690
MousePhenoabnormal motile cilium morphology

FBXO24 ARSA EGR4 DDHD1 TYSND1 RXRB TULP2 LRP8

4.56e-04370698MP:0013206
MousePhenosuperior-inferior ventricles

CFC1 CFC1B

4.96e-047692MP:0011254
MousePhenoabnormal cardiac outflow tract development

MEGF8 CFC1 LAMA5 CFC1B MRTFA

5.16e-04134695MP:0006126
MousePhenomuscular ventricular septal defect

MEGF8 CFC1 HIC2 CFC1B

5.61e-0477694MP:0010420
MousePhenoleft-sided isomerism

CFC1 LAMA5 CFC1B

6.17e-0434693MP:0000542
MousePhenoabnormal interventricular septum muscular part morphology

MEGF8 CFC1 HIC2 CFC1B

6.18e-0479694MP:0010498
MousePhenohairless

EDA HR

6.60e-048692MP:0003815
MousePhenoabnormal lateral geniculate nucleus morphology

MYCBP2 CHRNB2

6.60e-048692MP:0004165
MousePhenoabnormal vibrissa number

EDA HR

6.60e-048692MP:0009003
MousePhenovascular ring

CFC1 LAMA5 CFC1B

6.73e-0435693MP:0010466
MousePhenoatrioventricular septal defect

MEGF8 CFC1 LAMA5 CFC1B

7.79e-0484694MP:0010412
MousePhenofragmentation of sleep/wake states

CACNA1G CHRNB2

8.45e-049692MP:0009436
MousePhenoabnormal direction of heart looping

MEGF8 CFC1 CFC1B

8.58e-0438693MP:0004252
MousePhenoteratozoospermia

FBXO24 ARSA EGR4 DDHD1 TYSND1 RXRB TULP2 LRP8

8.67e-04408698MP:0005578
MousePhenoabnormal atrioventricular septum morphology

MEGF8 CFC1 LAMA5 CFC1B

8.89e-0487694MP:0010592
MousePhenoabnormal right subclavian artery morphology

CFC1 LAMA5 CFC1B

9.98e-0440693MP:0010487
MousePhenoabsent neurocranium

SCUBE1 LAMA5

1.28e-0311692MP:0000075
DomainGrowth_fac_rcpt_

CCN5 SCUBE1 CELSR1 HMCN1 MEGF8 LAMA5 LAMB1 FBXL19 TNXB IGFBPL1 FBN3 LRP8

3.24e-121568112IPR009030
DomainEGF_1

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 CFC1 LAMA5 LAMB1 CFC1B SSPOP AGRN TNXB FBN3 LRP8

4.42e-122558114PS00022
DomainEGF_2

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 CFC1 LAMA5 LAMB1 CFC1B SSPOP AGRN TNXB FBN3 LRP8

7.43e-122658114PS01186
DomainEGF

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 CFC1 LAMA5 LAMB1 CFC1B AGRN TNXB FBN3 LRP8

2.50e-112358113SM00181
DomainEGF-like_dom

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 CFC1 LAMA5 LAMB1 CFC1B AGRN TNXB FBN3 LRP8

5.16e-112498113IPR000742
DomainEGF-like_CS

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 CFC1 LAMA5 LAMB1 CFC1B AGRN TNXB FBN3 LRP8

9.27e-112618113IPR013032
DomainEGF_3

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 CFC1 CFC1B SSPOP AGRN TNXB FBN3 LRP8

3.91e-102358112PS50026
DomainTSP_1

CCN5 HMCN1 ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

1.01e-0863817PF00090
DomainTSP1

CCN5 HMCN1 ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

1.26e-0865817SM00209
DomainTSP1_rpt

CCN5 HMCN1 ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

1.26e-0865817IPR000884
DomainTSP1

CCN5 HMCN1 ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

1.26e-0865817PS50092
DomainEGF_CA

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 AGRN FBN3 LRP8

5.68e-08122818SM00179
DomainEGF-like_Ca-bd_dom

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 AGRN FBN3 LRP8

6.45e-08124818IPR001881
DomainEGF_LAM_2

CELSR1 MEGF8 LAMA5 LAMB1 AGRN

1.77e-0730815PS50027
DomainEGF_LAM_1

CELSR1 MEGF8 LAMA5 LAMB1 AGRN

1.77e-0730815PS01248
DomainASX_HYDROXYL

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 FBN3 LRP8

2.56e-07100817PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SNED1 SCUBE1 CELSR1 HMCN1 MEGF8 FBN3 LRP8

3.82e-07106817IPR000152
DomainLaminin_EGF

CELSR1 MEGF8 LAMA5 LAMB1 AGRN

3.97e-0735815PF00053
DomainEGF_Lam

CELSR1 MEGF8 LAMA5 LAMB1 AGRN

3.97e-0735815SM00180
DomainLaminin_EGF

CELSR1 MEGF8 LAMA5 LAMB1 AGRN

6.07e-0738815IPR002049
DomainEGF

SNED1 CELSR1 HMCN1 AGRN TNXB FBN3 LRP8

1.24e-06126817PF00008
DomainEGF_Ca-bd_CS

SNED1 SCUBE1 HMCN1 MEGF8 FBN3 LRP8

3.98e-0697816IPR018097
DomainEGF_CA

SNED1 SCUBE1 HMCN1 MEGF8 FBN3 LRP8

4.48e-0699816PS01187
DomainEGF_CA

SCUBE1 HMCN1 MEGF8 FBN3 LRP8

3.58e-0586815PF07645
Domain-

LDLRAD1 TMPRSS13 SSPOP LRP8

4.66e-05468144.10.400.10
DomainLDLRA_1

LDLRAD1 TMPRSS13 SSPOP LRP8

5.52e-0548814PS01209
DomainCFC

CFC1 CFC1B

5.56e-053812PF09443
DomainCryptic/Cripto_CFC-dom

CFC1 CFC1B

5.56e-053812IPR019011
DomainLDLRA_2

LDLRAD1 TMPRSS13 SSPOP LRP8

6.00e-0549814PS50068
DomainLDrepeatLR_classA_rpt

LDLRAD1 TMPRSS13 SSPOP LRP8

6.00e-0549814IPR002172
DomainLDLa

LDLRAD1 TMPRSS13 SSPOP LRP8

6.00e-0549814SM00192
DomainSR

SSC5D SSC4D TMPRSS13

1.69e-0425813SM00202
Domain-

SSC5D SSC4D TMPRSS13

1.69e-04258133.10.250.10
DomainSRCR_1

SSC5D SSC4D TMPRSS13

1.90e-0426813PS00420
DomaincEGF

SCUBE1 HMCN1 FBN3

1.90e-0426813IPR026823
DomainSRCR_2

SSC5D SSC4D TMPRSS13

1.90e-0426813PS50287
DomaincEGF

SCUBE1 HMCN1 FBN3

1.90e-0426813PF12662
DomainSRCR-like_dom

SSC5D SSC4D TMPRSS13

1.90e-0426813IPR017448
DomainSRCR

SSC5D SSC4D TMPRSS13

2.13e-0427813IPR001190
DomainLAM_G_DOMAIN

CELSR1 LAMA5 AGRN

5.94e-0438813PS50025
DomainGalactose-bd-like

MYCBP2 LAMA5 LAMB1 SSPOP

7.44e-0494814IPR008979
DomainLamG

CELSR1 LAMA5 AGRN

9.16e-0444813SM00282
DomainLdl_recept_a

LDLRAD1 SSPOP LRP8

9.78e-0445813PF00057
DomainFol_N

SNED1 AGRN

9.96e-0411812IPR003645
DomainFOLN

SNED1 AGRN

9.96e-0411812SM00274
DomainNuclear_hrmn_rcpt

NR0B1 NR4A1 RXRB

1.04e-0346813IPR001723
Domain-

NR0B1 NR4A1 RXRB

1.11e-03478131.10.565.10
DomainHOLI

NR0B1 NR4A1 RXRB

1.18e-0348813SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR0B1 NR4A1 RXRB

1.18e-0348813IPR000536
DomainHormone_recep

NR0B1 NR4A1 RXRB

1.18e-0348813PF00104
DomainEGF_3

SCUBE1 MEGF8

1.19e-0312812PF12947
DomainEGF_dom

SCUBE1 MEGF8

1.19e-0312812IPR024731
DomainCUB

SCUBE1 MEGF8 ADAMTS13

1.57e-0353813PS01180
DomainIBR

RNF31 RBCK1

1.63e-0314812PF01485
DomainTryp_SPc

CFD TMPRSS13 KLK9 TYSND1

1.68e-03117814SM00020
DomainIBR_dom

RNF31 RBCK1

1.88e-0315812IPR002867
DomainTrypsin

CFD TMPRSS13 KLK9 TYSND1

1.90e-03121814PF00089
DomainTrypsin_dom

CFD TMPRSS13 KLK9 TYSND1

1.90e-03121814IPR001254
Domain-

GATA6 NR4A1 RXRB

1.94e-03578133.30.50.10
DomainCUB_dom

SCUBE1 MEGF8 ADAMTS13

1.94e-0357813IPR000859
DomainPeptidase_S1_PA

CFD TMPRSS13 KLK9 TYSND1

2.02e-03123814IPR009003
DomainLaminin_G

CELSR1 LAMA5 AGRN

2.04e-0358813IPR001791
DomainZnf_NHR/GATA

GATA6 NR4A1 RXRB

2.04e-0358813IPR013088
DomainLaminin_N

LAMA5 LAMB1

2.14e-0316812IPR008211
DomainLAMININ_NTER

LAMA5 LAMB1

2.14e-0316812PS51117
DomainLaminin_N

LAMA5 LAMB1

2.14e-0316812PF00055
DomainLamNT

LAMA5 LAMB1

2.14e-0316812SM00136
DomainEMI

EMILIN3 SSPOP

2.42e-0317812PS51041
DomainIB

CCN5 IGFBPL1

2.72e-0318812SM00121
DomainIGFBP-like

CCN5 IGFBPL1

3.36e-0320812IPR000867
DomainIGFBP

CCN5 IGFBPL1

3.36e-0320812PF00219
DomainRCC1

FBXO24 MYCBP2

3.36e-0320812PF00415
DomainIGFBP_N_2

CCN5 IGFBPL1

3.36e-0320812PS51323
DomainRCC1_1

FBXO24 MYCBP2

3.70e-0321812PS00625
DomainRCC1_2

FBXO24 MYCBP2

3.70e-0321812PS00626
DomainSRCR

SSC5D SSC4D

3.70e-0321812PF00530
DomainRCC1_3

FBXO24 MYCBP2

3.70e-0321812PS50012
Domainzf-RanBP

RNF31 RBCK1

4.06e-0322812PF00641
DomainReg_chr_condens

FBXO24 MYCBP2

4.06e-0322812IPR000408
Domain-

FBXO24 MYCBP2

4.06e-03228122.130.10.30
DomainKazal_1

AGRN IGFBPL1

4.06e-0322812PF00050
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

7.17e-0739625M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

7.17e-0739625MM15165
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

1.18e-0568625M27303
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTSL5 ADAMTS13 THSD7B SSPOP AGRN ADAMTSL4

3.78e-05143626M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTSL5 CYP26C1 ADAMTS13 THSD7B SSPOP AGRN ADAMTSL4

1.09e-04250627M27554
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

1.15e-04109625MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

1.25e-04111625M27416
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_TNF_NFKB_SIGNALING_PATHWAY_LUBAC_MEDIATED_LINEAR_UBIQUITINATION

RNF31 RBCK1

2.82e-046622M47899
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

SCUBE1 LAMA5 LAMB1 EMILIN3 AGRN TNXB FBN3

3.33e-04300627M610
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA5 LAMB1 AGRN TNXB

3.43e-0476624M27219
PathwayKEGG_ECM_RECEPTOR_INTERACTION

LAMA5 LAMB1 AGRN TNXB

5.03e-0484624M7098
PathwayWP_NUCLEAR_RECEPTORS

NR0B1 NR4A1 RXRB

6.12e-0438623M39657
PathwayWP_NUCLEAR_RECEPTORS

NR0B1 NR4A1 RXRB

6.12e-0438623MM15865
PathwayPID_INTEGRIN4_PATHWAY

LAMA5 LAMB1

1.02e-0311622M158
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA5 LAMB1 RXRB

1.07e-0346623M239
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR0B1 NR4A1 RXRB

1.22e-0348623MM14987
PathwayWP_MIR127_IN_MESENDODERM_DIFFERENTIATION

CFC1 CFC1B

1.22e-0312622MM15910
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

CCN5 HMCN1 ADAMTSL5 ADAMTS13 THSD7B SSPOP ADAMTSL4

5.93e-107583720637190
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HMCN1 LAMB1 EMILIN3 SSPOP AGRN TNXB

1.03e-086483622261194
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

RNF31 MEGF8 HAP1 NR0B1 LAMB1 CACNA1G MON1A NR4A1 SSPOP AGRN GFI1 TTC19

2.29e-08608831216713569
Pubmed

GATA6, SF1, NGFIB and DAX1 in the remodeled subcapsular zones in primary aldosteronism.

NR0B1 GATA6 NR4A1

5.23e-08483324531914
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRPM4 CELSR1 ZBED4 MEGF8 ADAMTSL5 MYCBP2 LONRF1 LAMA5 PFAS FBXL19 AGRN ANO8 MAP3K5 HR

3.38e-071105831435748872
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

LAMA5 LAMB1 AGRN

3.68e-061383312682087
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HMCN1 LAMA5 LAMB1 SSPOP AGRN TNXB

4.08e-0617583628071719
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

MEGF8 PKD1L1 CFC1 LAMA5 CFC1B

4.32e-0610083525807483
Pubmed

RBCK1 promotes hepatocellular carcinoma metastasis and growth by stabilizing RNF31.

RNF31 RBCK1

5.63e-06283235869046
Pubmed

ASK1 Mediates Nur77 Expression in T-Cell Receptor Mediated Thymocyte Apoptosis.

NR4A1 MAP3K5

5.63e-06283232121597
Pubmed

The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer.

CFC1 CFC1B

5.63e-06283211174844
Pubmed

KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis.

TRPM4 KCTD5

5.63e-06283232301552
Pubmed

Agrin binds to the nerve-muscle basal lamina via laminin.

LAMB1 AGRN

5.63e-0628329151673
Pubmed

Identification of differentially expressed genes in mouse development using differential display and in situ hybridization.

CFC1 CFC1B

5.63e-06283211327798
Pubmed

Subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation and early cardiogenesis.

CFC1 CFC1B

5.63e-06283211024280
Pubmed

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.

CFC1 CFC1B

5.63e-06283211062482
Pubmed

Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.

RNF31 RBCK1

5.63e-06283226008899
Pubmed

The DNA sequence of human chromosome 22.

SCUBE1 CELSR1 ARSA ZBED4 SDF2L1 HIC2 MRTFA

7.86e-0630083710591208
Pubmed

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.

CFC1 CFC1B

1.69e-05383216835440
Pubmed

A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex.

RNF31 RBCK1

1.69e-05383222430200
Pubmed

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita.

NR0B1 RXRB

1.69e-0538327990953
Pubmed

Linear Ubiquitin Code: Its Writer, Erasers, Decoders, Inhibitors, and Implications in Disorders.

RNF31 RBCK1

1.69e-05383232403254
Pubmed

Serine 165 phosphorylation of SHARPIN regulates the activation of NF-κB.

RNF31 RBCK1

1.69e-05383233392484
Pubmed

Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.

RNF31 RBCK1

1.69e-05383224141947
Pubmed

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.

RNF31 RBCK1

1.69e-05383226525107
Pubmed

Biochemical and functional characterization of the N-terminal ubiquitin-like domain of human SHARPIN.

RNF31 RBCK1

1.69e-05383234965468
Pubmed

Structural basis for ubiquitylation by HOIL-1.

RNF31 RBCK1

1.69e-05383236685275
Pubmed

HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.

RNF31 RBCK1

1.69e-05383225118570
Pubmed

Determinants of laminin polymerization revealed by the structure of the α5 chain amino-terminal region.

LAMA5 LAMB1

1.69e-05383221311558
Pubmed

LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB.

RNF31 RBCK1

1.69e-05383228481331
Pubmed

Identification and molecular analysis of RNF31 Q622H germline polymorphism.

RNF31 RBCK1

1.69e-05383236276481
Pubmed

Nuclear receptors in Leydig cell gene expression and function.

NR0B1 NR4A1 RXRB

1.95e-052283320375256
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

CCN5 SSC5D ARSA LAMB1 AGRN ADAMTSL4

2.95e-0524883624006456
Pubmed

Cooperative Domain Formation by Homologous Motifs in HOIL-1L and SHARPIN Plays A Crucial Role in LUBAC Stabilization.

RNF31 RBCK1

3.37e-05483229694895
Pubmed

Expression of laminin chains by central neurons: analysis with gene and protein trapping techniques.

LAMA5 LAMB1

3.37e-05483212820173
Pubmed

Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3.

NR0B1 GATA6

3.37e-05483227601327
Pubmed

Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.

RNF31 RBCK1

3.37e-05483212629548
Pubmed

Differential Involvement of the Npl4 Zinc Finger Domains of SHARPIN and HOIL-1L in Linear Ubiquitin Chain Assembly Complex-Mediated Cell Death Protection.

RNF31 RBCK1

3.37e-05483226976635
Pubmed

Linear ubiquitin assembly complex regulates lung epithelial-driven responses during influenza infection.

RNF31 RBCK1

3.37e-05483231714898
Pubmed

Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation.

LAMA5 LAMB1

3.37e-0548329299121
Pubmed

Regulation and Function of Laminin A5 during Mouse and Human Decidualization.

LAMA5 LAMB1

3.37e-05483235008625
Pubmed

The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate TNFR2-induced canonical NF-κB signaling.

RNF31 RBCK1

3.37e-05483229378181
Pubmed

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

RNF31 RBCK1

3.37e-05483223942237
Pubmed

Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.

RNF31 RBCK1

3.37e-05483217069764
Pubmed

Cripto in tumors and embryo development.

CFC1 CFC1B

3.37e-05483211825688
Pubmed

Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes prostate cancer cell migration.

LAMA5 LAMB1

3.37e-05483215967115
Pubmed

Linear ubiquitination prevents inflammation and regulates immune signalling.

RNF31 RBCK1

3.37e-05483221455173
Pubmed

Synaptic transmission is impaired at neuronal autonomic synapses in agrin-null mice.

AGRN CHRNB2

3.37e-05483217443806
Pubmed

Directly recruited GATA6 + peritoneal cavity macrophages contribute to the repair of intestinal serosal injury.

GATA6 NR4A1

3.37e-05483234911964
Pubmed

Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1.

CFC1 CFC1B

3.37e-0548329576836
Pubmed

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate.

RNF31 RBCK1

3.37e-05483222791023
Pubmed

Laminin-1 reexpression in Alport mouse glomerular basement membranes.

LAMA5 LAMB1

3.37e-05483212631063
Pubmed

The hepatitis C virus protein NS3 suppresses TNF-α-stimulated activation of NF-κB by targeting LUBAC.

RNF31 RBCK1

3.37e-05483226577923
Pubmed

Role of the EGF-CFC gene cripto in cell differentiation and embryo development.

CFC1 CFC1B

3.37e-05483211992720
Pubmed

E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis.

RNF31 NR0B1

3.37e-05483219237537
Pubmed

An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.

LAMA5 AGRN

3.37e-05483211565031
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

LAMA5 LAMB1 EMILIN3 ADAMTSL4 TNXB

3.40e-0515383525037231
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

LAMA5 LAMB1 AGRN ADAMTSL4

3.95e-057983418757743
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMA5 LAMB1 AGRN

4.58e-052983322613833
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

LDLRAD1 RNF31 CACNA1G EDA ADAMTSL4 MRTFA RBCK1

5.11e-0540283724722188
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

HMCN1 ADAMTSL5 LAMA5 LAMB1 AGRN

5.16e-0516783522159717
Pubmed

The Linear Ubiquitin Assembly Complex Modulates Latent Membrane Protein 1 Activation of NF-κB and Interferon Regulatory Factor 7.

RNF31 RBCK1

5.60e-05583227903798
Pubmed

The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease.

RNF31 RBCK1

5.60e-05583227893701
Pubmed

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.

NR4A1 RXRB

5.60e-0558327705655
Pubmed

Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.

LAMA5 LAMB1

5.60e-05583210964500
Pubmed

A differential display strategy identifies Cryptic, a novel EGF-related gene expressed in the axial and lateral mesoderm during mouse gastrulation.

CFC1 CFC1B

5.60e-0558329053319
Pubmed

Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts.

LAMA5 LAMB1

5.60e-0558329719032
Pubmed

Laminin-10 is crucial for hair morphogenesis.

LAMA5 LAMB1

5.60e-05583212743034
Pubmed

The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation.

NR0B1 NR4A1

5.60e-05583215155786
Pubmed

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis.

RNF31 RBCK1

5.60e-05583221455181
Pubmed

SHARPIN at the nexus of integrin, immune, and inflammatory signaling in human platelets.

RNF31 RBCK1

5.60e-05583230804189
Pubmed

Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb.

CFC1 CFC1B

5.60e-05583225224222
Pubmed

Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly.

RNF31 RBCK1

5.60e-05583228978479
Pubmed

A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.

RNF31 RBCK1

5.60e-05583228919039
Pubmed

Molecular basis and regulation of OTULIN-LUBAC interaction.

RNF31 RBCK1

5.60e-05583224726323
Pubmed

Molecular profiling of the vestibular lamina highlights a key role for Hedgehog signalling.

SNED1 SCUBE1 RAMP3

5.61e-053183336971701
Pubmed

Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling.

RNF31 RBCK1

8.39e-05683233215740
Pubmed

HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.

RNF31 RBCK1

8.39e-05683225284787
Pubmed

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.

RNF31 RBCK1

8.39e-05683223708998
Pubmed

A role of the cryptic gene in the correct establishment of the left-right axis.

CFC1 CFC1B

8.39e-05683210574770
Pubmed

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway.

CFC1 CFC1B

8.39e-05683212052855
Pubmed

GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth.

CFC1 CFC1B

8.39e-05683217991893
Pubmed

Extracellular matrix of secondary lymphoid organs impacts on B-cell fate and survival.

LAMA5 AGRN

8.39e-05683223847204
Pubmed

Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.

LAMA5 AGRN

8.39e-05683215668394
Pubmed

Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction.

RNF31 RBCK1

8.39e-05683221292167
Pubmed

Laminin-10 and Lutheran blood group glycoproteins in adhesion of human endothelial cells.

LAMA5 LAMB1

8.39e-05683216236823
Pubmed

The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.

RNF31 RBCK1

8.39e-05683236631489
Pubmed

The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO.

RNF31 RBCK1

8.39e-05683223453807
Pubmed

Integrin binding specificity of laminin-10/11: laminin-10/11 are recognized by alpha 3 beta 1, alpha 6 beta 1 and alpha 6 beta 4 integrins.

LAMA5 LAMB1

8.39e-05683210671376
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

LAMA5 LAMB1 AGRN TNXB

8.82e-059783427559042
Pubmed

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.

RNF31 RBCK1

1.17e-04783227523608
Pubmed

Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.

RNF31 RBCK1

1.17e-04783224461064
Pubmed

Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.

RNF31 RBCK1

1.17e-04783223104095
Pubmed

A ubiquitin ligase complex assembles linear polyubiquitin chains.

RNF31 RBCK1

1.17e-04783217006537
Pubmed

The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC.

RNF31 RBCK1

1.17e-04783232019898
Pubmed

Cross-regulation between LUBAC and caspase-1 modulates cell death and inflammation.

RNF31 RBCK1

1.17e-04783232122970
Pubmed

Laminin-10/11 and fibronectin differentially prevent apoptosis induced by serum removal via phosphatidylinositol 3-kinase/Akt- and MEK1/ERK-dependent pathways.

LAMA5 LAMB1

1.17e-04783211891225
Pubmed

Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.

CFC1 CFC1B

1.17e-04783210521397
Pubmed

Subquinocin, a small molecule inhibitor of CYLD and USP-family deubiquitinating enzymes, promotes NF-κB signaling.

RNF31 RBCK1

1.17e-04783231898971
Pubmed

A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis.

RNF31 RBCK1

1.17e-04783230913450
InteractionTNFRSF6B interactions

ARSA LDLRAD1 CFC1 SDF2L1

5.73e-0631774int:TNFRSF6B
InteractionFIBIN interactions

CFD CELSR1 MEGF8 LAMB1 SDF2L1

7.63e-0671775int:FIBIN
InteractionHOXA1 interactions

CCN5 SSC4D MEGF8 LONRF1 LAMA5 AGRN ADAMTSL4 RBCK1 HR

8.49e-06356779int:HOXA1
InteractionCFC1 interactions

CELSR1 MEGF8 CFC1 LAMA5 LAMB1 AGRN

8.74e-06126776int:CFC1
InteractionEXT2 interactions

CFD TMPRSS13 CFC1 SDF2L1 TTC19

1.29e-0579775int:EXT2
InteractionLAMB1 interactions

CFD BTF3 CFC1 LAMA5 LAMB1 SDF2L1

1.73e-05142776int:LAMB1
InteractionSEZ6L2 interactions

RAMP3 TMPRSS13 CFC1 SDF2L1

1.97e-0542774int:SEZ6L2
InteractionCREB5 interactions

CFD SSC4D KRTAP19-3 AGRN ADAMTSL4 RBCK1

3.90e-05164776int:CREB5
InteractionGGH interactions

CFD CELSR1 MEGF8 MYCBP2 LAMA5 LAMB1 FBXL19

3.99e-05243777int:GGH
InteractionEDN3 interactions

CELSR1 ARSA MEGF8 LAMA5 AGRN

5.85e-05108775int:EDN3
InteractionPTPRK interactions

CFD ARSA TMPRSS13 MEGF8 LAMA5 LAMB1

5.97e-05177776int:PTPRK
InteractionPOGLUT1 interactions

CFD TMPRSS13 MYCBP2 CFC1 SDF2L1

6.96e-05112775int:POGLUT1
InteractionLAMA5 interactions

CFD CFC1 LAMA5 LAMB1 SDF2L1

8.57e-05117775int:LAMA5
InteractionADAM9 interactions

MIDN LDLRAD1 TMPRSS13 CFC1 SDF2L1

9.28e-05119775int:ADAM9
InteractionEOGT interactions

CFD TMPRSS13 CFC1 SDF2L1

9.89e-0563774int:EOGT
InteractionPIGT interactions

CFD NAGK LDLRAD1 CFC1 LAMB1 SDF2L1

1.20e-04201776int:PIGT
InteractionDNAJB9 interactions

CFD CELSR1 TMPRSS13 LAMA5 LAMB1 AGRN

1.24e-04202776int:DNAJB9
InteractionCELSR1 interactions

CELSR1 CFC1 SDF2L1 ADAMTS13

1.33e-0468774int:CELSR1
InteractionWNT5A interactions

LDLRAD1 MYCBP2 SDF2L1 CHRNB2

1.41e-0469774int:WNT5A
InteractionSELENON interactions

CFD CFC1 SDF2L1 EMILIN3

1.49e-0470774int:SELENON
InteractionLAMC1 interactions

CFD CFC1 LAMA5 LAMB1 SDF2L1

1.68e-04135775int:LAMC1
InteractionGFI1B interactions

RNF31 MEGF8 LAMB1 MON1A AGRN

1.74e-04136775int:GFI1B
InteractionMYL12B interactions

CFD MIDN BTF3 MEPCE AGRN

1.86e-04138775int:MYL12B
InteractionIGFL3 interactions

MYCBP2 LAMA5 LAMB1 AGRN

1.95e-0475774int:IGFL3
InteractionFUT8 interactions

CFD CELSR1 RAMP3 TMPRSS13 CHRNB2

2.13e-04142775int:FUT8
InteractionSNED1 interactions

SNED1 CFD

2.14e-046772int:SNED1
InteractionCRP interactions

CFD LAMA5 LAMB1 AGRN

2.16e-0477774int:CRP
InteractionSDF2L1 interactions

CFD CELSR1 MEGF8 LAMA5 LAMB1 SDF2L1 AGRN

2.30e-04322777int:SDF2L1
CytobandEnsembl 112 genes in cytogenetic band chr22q13

SCUBE1 CELSR1 ARSA ZBED4 MRTFA

3.42e-04330835chr22q13
Cytoband22q13

SCUBE1 MRTFA

1.02e-032683222q13
Cytoband1q21.3

C2CD4D ADAMTSL4 CHRNB2

1.28e-031178331q21.3
Cytoband22q13.33

ARSA ZBED4

2.18e-033883222q13.33
Cytoband7q22

FBXO24 LAMB1

2.18e-03388327q22
CytobandEnsembl 112 genes in cytogenetic band chr1p32

LDLRAD1 TACSTD2 LRP8

2.85e-03155833chr1p32
Cytoband2q21.1

CFC1 CFC1B

5.00e-03588322q21.1
GeneFamilyADAMTS like

ADAMTSL5 ADAMTSL4

1.56e-047502947
GeneFamilyNuclear hormone receptors

NR0B1 NR4A1 RXRB

3.35e-044950371
GeneFamilyLaminin subunits

LAMA5 LAMB1

4.86e-0412502626
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RNF31 RBCK1

1.52e-032150289
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

SSC5D SSC4D

2.52e-03275021253
CoexpressionNABA_ECM_GLYCOPROTEINS

CCN5 SNED1 HMCN1 LAMA5 LAMB1 EMILIN3 SSPOP AGRN TNXB IGFBPL1 FBN3

2.37e-111968111M3008
CoexpressionNABA_MATRISOME

CCN5 SNED1 SCUBE1 HMCN1 MEGF8 ADAMTSL5 CBLN2 CFC1 LAMA5 LAMB1 EMILIN3 CFC1B ADAMTS13 EDA SSPOP AGRN ADAMTSL4 TNXB IGFBPL1 FBN3

2.89e-1110268120M5889
CoexpressionNABA_MATRISOME

CCN5 SNED1 SCUBE1 HMCN1 MEGF8 ADAMTSL5 CBLN2 CFC1 LAMA5 LAMB1 EMILIN3 CFC1B ADAMTS13 EDA SSPOP AGRN ADAMTSL4 TNXB IGFBPL1

1.75e-1010088119MM17056
CoexpressionNABA_ECM_GLYCOPROTEINS

CCN5 SNED1 HMCN1 LAMA5 LAMB1 EMILIN3 SSPOP AGRN TNXB IGFBPL1

4.00e-101918110MM17059
CoexpressionNABA_CORE_MATRISOME

CCN5 SNED1 HMCN1 LAMA5 LAMB1 EMILIN3 SSPOP AGRN TNXB IGFBPL1 FBN3

8.79e-102758111M5884
CoexpressionNABA_CORE_MATRISOME

CCN5 SNED1 HMCN1 LAMA5 LAMB1 EMILIN3 SSPOP AGRN TNXB IGFBPL1

1.12e-082708110MM17057
CoexpressionNABA_BASEMENT_MEMBRANES

HMCN1 LAMA5 LAMB1 AGRN

7.11e-0640814M5887
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

CDC42BPG HAP1 PFAS ZFTA NR4A1 GFI1

3.69e-05200816M9188
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

SCUBE1 CELSR1 CBLN2 EMILIN3 TACSTD2 TNXB GFI1 IGFBPL1 CHRNB2

8.73e-05591819M2019
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

SCUBE1 CELSR1 CBLN2 EMILIN3 TACSTD2 TNXB GFI1 IGFBPL1 CHRNB2

9.92e-05601819MM866
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 SSC5D SCUBE1 HMCN1 LAMB1 ADAMTS13 TNXB

4.87e-08181837b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCN5 SNED1 CFD HMCN1 LAMB1 NR4A1 TNXB

9.63e-0820083744317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCellcellseq2-Mesenchymal-Fibroblastic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCN5 SNED1 CFD HMCN1 LAMB1 NR4A1 TNXB

9.63e-082008371c10597edd532bf172ca09870a937d35e2585081
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCN5 SNED1 CFD HMCN1 LAMB1 NR4A1 TNXB

9.63e-08200837440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MIDN ADAMTSL5 MON1A ADAMTSL4 MRTFA TULP2

8.18e-071718362b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MIDN ADAMTSL5 MON1A ADAMTSL4 MRTFA TULP2

8.18e-07171836dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CELSR1 LAMA5 MAGI3 TACSTD2 AGRN FBN3

1.42e-06188836eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

SNED1 SSC5D HMCN1 ADAMTSL5 ADAMTSL4 TNXB

1.42e-06188836409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIDN TMPRSS13 WEE1 NR4A1 TACSTD2 TNXB

1.46e-061898361cfc1fe27c4b57b4e52700fa8f679ce172cee5a9
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SNED1 CFD GATA6 NR4A1 TNXB HR

1.76e-06195836ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SCUBE1 LAMA5 MAGI3 TACSTD2 AGRN FBN3

1.81e-06196836150554fa06868d29b0608189862eef6505ba757f
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCN5 SSC5D HMCN1 LAMB1 TNXB HR

1.86e-061978366d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCN5 SNED1 CFD HMCN1 LAMB1 TNXB

2.03e-06200836c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCN5 SNED1 CFD HMCN1 LAMB1 TNXB

2.03e-06200836137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CCN5 SNED1 CFD HMCN1 LAMB1 TNXB

2.03e-0620083625d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4|TCGA-Bladder / Sample_Type by Project: Shred V9

CFD SCUBE1 MIDN WEE1 NR4A1

9.07e-06150835bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D LONRF1 GATA6 CACNA1G NR4A1

1.32e-051628355f009b231f21861afee9cc0c569082e1135f929c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SSC5D LONRF1 GATA6 CACNA1G NR4A1

1.32e-05162835b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CBLN2 LAMA5 LAMB1 EMILIN3 MAGI3

1.44e-05165835c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 ARSA HAP1 ZFTA NR4A1

1.57e-05168835de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS13 LAMA5 TACSTD2 IGFBPL1 HR

1.76e-05172835c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDC42BPG LAMA5 NR4A1 TACSTD2 LRP8

1.86e-05174835207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 SSC5D HMCN1 LAMB1 TNXB

1.91e-051758351799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 DGKI MAGI3 FBN3 MAP3K5

2.07e-0517883551d2188406f04329311b2efd1108fc36617a860e
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAMTSL5 MON1A ADAMTSL4 MRTFA TULP2

2.31e-05182835dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD SSC5D TNXB TULP2

2.31e-05182835d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

SCUBE1 LAMA5 TACSTD2 AGRN FBN3

2.43e-05184835cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SCUBE1 LAMA5 TACSTD2 AGRN FBN3

2.43e-05184835bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE1 ADAMTSL5 LAMB1 ADAMTS13 TNXB

2.49e-05185835f814ec9d4ade717a0109398e9768d0d66f09317b
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

CCN5 SNED1 CFD SSC5D TNXB

2.49e-05185835fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE1 ADAMTSL5 LAMB1 ADAMTS13 TNXB

2.49e-0518583540e958511790e84321da5ccf735f9974c06a0263
ToppCelldroplet-Liver-LIVER_HEP-30m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE1 ADAMTSL5 LAMB1 ADAMTS13 TNXB

2.49e-051858355f2eeba80aff145e85cfd81e2890a155406badb9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC42BPG CELSR1 MIDN NR4A1 HR

2.56e-05186835bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

CELSR1 LAMA5 MAGI3 AGRN FBN3

2.56e-0518683509d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CELSR1 LAMA5 MAGI3 AGRN FBN3

2.62e-051878354ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCellwk_08-11-Mesenchymal-Mesothelial-Early_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SSC4D CFC1 GATA6 LAMA5 LRP8

2.69e-051888356151051c027c7ff7d5d4bf5f1e11d7fe58eb22ed
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCUBE1 DDHD1 LAMA5 LAMB1 CACNA1G

2.69e-05188835997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 SNED1 CFD SSC5D TNXB

2.76e-05189835d531399749409d614adca13d181830c6e3287508
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

SCUBE1 LAMA5 MAGI3 TACSTD2 AGRN

2.90e-0519183566875b2ec2c510489407f3e433a90cdf74a15094
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCN5 CFD NR4A1 TNXB MAP3K5

2.90e-051918352c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCN5 SSC5D C2CD4D CACNA1G TNXB

2.90e-0519183524dc77ee8de01b42559f92721655f4281b114e17
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SNED1 RAMP3 HMCN1 LAMB1 AGRN

2.90e-05191835dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

SNED1 CFD LAMB1 TNXB MRTFA

3.13e-0519483511c79a8c56ece42713b04b321982e41e239f07a5
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 SSC5D HMCN1 LAMB1 TNXB

3.13e-051948358fae8061b350336299aa81f378e07deadbd55123
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 SSC5D HMCN1 LAMB1 TNXB

3.13e-051948354d7d24390fdb379f943ddcc70a63f23955e10163
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

SCUBE1 LAMA5 TACSTD2 AGRN FBN3

3.21e-0519583507a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD HMCN1 LAMB1 TNXB

3.21e-05195835df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD HMCN1 LAMB1 TNXB

3.21e-051958354243190ad291d56694e2155954dbaa879c9d3844
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SCUBE1 LAMA5 TACSTD2 AGRN FBN3

3.21e-05195835b65511770ed67f7447847e2187555b362988af45
ToppCellwk_20-22-Epithelial-Distal_epithelial-type_I_pneumocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA5 MAGI3 TACSTD2 AGRN FBN3

3.29e-05196835e24a7aaf41793abba66c1189d933ca05b14c1af9
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD HMCN1 LAMB1 TNXB

3.29e-051968359737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD HMCN1 LAMB1 TNXB

3.29e-0519683542e9828222a9663525d571633e8a454c30bfa7f8
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELSR1 HMCN1 HAP1 GATA6 ZFHX2

3.29e-05196835e386526332138e636aef2542c11316347a45689c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD HMCN1 LAMB1 TNXB

3.29e-05196835cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD HMCN1 LAMB1 TNXB

3.37e-0519783594a9603cbd3516fbcce871909693b88f20d41713
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE1 LONRF1 EMILIN3 THSD7B NR4A1

3.37e-05197835dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 SNED1 CFD SSC5D TNXB

3.37e-05197835c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCN5 CFD HMCN1 LAMB1 TNXB

3.37e-0519783513896ec65ccda0b928c91d41112dc01b480036b7
ToppCell10x5'v1-week_12-13-Endothelial-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RAMP3 GATA6 LAMA5 LAMB1 AGRN

3.45e-05198835122215d9288533ad03562cf777e846504863df9a
ToppCell10x5'v1-week_12-13-Endothelial|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RAMP3 GATA6 LAMA5 LAMB1 AGRN

3.45e-05198835307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LAMA5 MAGI3 TACSTD2 AGRN FBN3

3.45e-05198835c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

SSC5D HMCN1 LAMB1 ADAMTS13 TNXB

3.45e-05198835bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCN5 CFD HMCN1 LAMB1 TNXB

3.45e-05198835f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CCN5 CFD HMCN1 CFC1 LAMB1

3.53e-0519983528c1722deef3b8347371c7359be7c64b95780de3
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 SCUBE1 EMILIN3 THSD7B GFI1

3.53e-05199835fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SCUBE1 LAMA5 TACSTD2 AGRN FBN3

3.53e-051998355a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 SCUBE1 EMILIN3 NR4A1 TNXB

3.53e-051998353835452e4848d7f7dd8651c17b746b271ef39688
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Late_airway_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CELSR1 TMPRSS13 LAMA5 MAGI3 TACSTD2

3.53e-05199835494461665f945ce6c97299c58f7785e90dec5812
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CELSR1 LAMA5 MAGI3 TACSTD2 AGRN

3.53e-05199835af664e0d41a889a75dbf6cf0d50acd26f5ab3a3a
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 SCUBE1 EMILIN3 NR4A1 TNXB

3.53e-051998359c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCN5 CFD HMCN1 LAMB1 TNXB

3.53e-0519983566a79732caf2f04c09b4d9832377aa01ca477677
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN5 CFD LAMB1 ADAMTSL4 TNXB

3.62e-05200835933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCellcellseq-Mesenchymal-Fibroblastic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CCN5 CFD HMCN1 LAMB1 TNXB

3.62e-052008358978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN5 CFD NR4A1 ADAMTSL4 TNXB

3.62e-05200835db6281b5d4032116310db379d9175d790994c99c
ToppCellnormal_Lung-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

CCN5 CFD MIDN NR4A1 TNXB

3.62e-052008356d8f6a6b3f61c529fbed1376659641030abf4f2c
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFD SSC5D LAMB1 ADAMTSL4 TNXB

3.62e-052008356f7f015b5fa1f52374f2c7d9ba339012395eda5f
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCUBE1 LAMA5 MAGI3 TACSTD2 AGRN

3.62e-05200835c6f211bbadd0c9be776c58807249e06764df47dc
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CCN5 SSC5D HMCN1 LAMB1 TNXB

3.62e-052008356e3d1ae0ef84d3075afa40129a41169996462672
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN5 CFD NR4A1 ADAMTSL4 TNXB

3.62e-0520083510f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SNED1 CFD HMCN1 LAMB1 TNXB

3.62e-05200835b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFD SSC5D LAMB1 ADAMTSL4 TNXB

3.62e-052008353a164e3971bcd62b148b813171c103adb81f972e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SCUBE1 LAMA5 MAGI3 TACSTD2 AGRN

3.62e-052008355f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN5 CFD NR4A1 ADAMTSL4 TNXB

3.62e-05200835a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SCUBE1 LAMA5 MAGI3 TACSTD2 AGRN

3.62e-05200835e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellBiopsy_Control_(H.)-Epithelial-AT1|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

SCUBE1 LAMA5 MAGI3 TACSTD2 AGRN

3.62e-052008353a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CCN5 SNED1 CFD LAMB1 TNXB

3.62e-052008350c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell5'-Adult-LargeIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCN5 CFD LAMB1 ADAMTSL4 TNXB

3.62e-052008355a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E16.5-samps / Age Group, Lineage, Cell class and subclass

SSC5D EMILIN3 THSD7B TNXB

9.95e-051298345e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

SCUBE1 C16orf95 DGKI MAGI3

1.36e-0414083445d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRPM4 RAMP3 PIK3R6 EGR4

1.40e-0414183440ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMA5 FBXL19 SSPOP ZNF513

1.48e-04143834d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMA5 FBXL19 SSPOP ZNF513

1.48e-041438348900b92a24289204b9ec7baccc11594fec7694f1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFD DGKI MAGI3 FBN3

1.60e-04146834ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Ndrg2_(Ndrg2)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CYP26C1 SSPOP TULP2

2.12e-0462833f7697057fb5568368ec7edead2bcdd25ede7627b
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2-Tfr-Oligodendrocyte.Tfr.Ndrg2_(Ndrg2)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

CYP26C1 SSPOP TULP2

2.12e-046283319867e62ca7e024572192a2654e2eb8f226bdd60
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

CFD HMCN1 LAMB1 TNXB

2.22e-041598343f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA5 DGKI TACSTD2 AGRN

2.27e-0416083458ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MIDN LONRF1 GFI1 TULP2

2.33e-04161834f5da03c426f3124ea302bd343b6bca81cafee858
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-6|TCGA-Adrenal / Sample_Type by Project: Shred V9

CCN5 SSC4D NR0B1 EDA

2.39e-041628340e8fb83acb8ea9905cc3ca985feb8a00931549ff
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MIDN LONRF1 GFI1 TULP2

2.39e-041628344e3bf16799c6552366d4c7e42b1328a05dcad7e7
DrugRgd Peptide

CFD ADAMTSL5 LAMA5 LAMB1 EDA ADAMTSL4 TNXB FBN3

2.39e-06239828CID000104802
Diseasevisceral heterotaxy (is_implicated_in)

PKD1L1 CFC1 CFC1B

3.84e-0612783DOID:0050545 (is_implicated_in)
DiseasePOLYGLUCOSAN BODY MYOPATHY 1 WITH OR WITHOUT IMMUNODEFICIENCY

RNF31 RBCK1

6.90e-062782C4014605
Diseaseglycerate measurement

HMCN1 THSD7B AGRN

7.90e-0615783EFO_0021029
Diseasedouble outlet right ventricle (implicated_via_orthology)

CFC1 CFC1B

2.07e-053782DOID:6406 (implicated_via_orthology)
Diseasedextro-looped transposition of the great arteries (implicated_via_orthology)

CFC1 CFC1B

4.12e-054782DOID:0060770 (implicated_via_orthology)
Diseaseright atrial isomerism (implicated_via_orthology)

CFC1 CFC1B

4.12e-054782DOID:0060856 (implicated_via_orthology)
Diseasevisceral heterotaxy (implicated_via_orthology)

MEGF8 CFC1 CFC1B

1.29e-0437783DOID:0050545 (implicated_via_orthology)
DiseaseSitus ambiguous

PKD1L1 CFC1

2.45e-049782C1167664
Diseasetetralogy of Fallot (is_implicated_in)

GATA6 CFC1B

5.28e-0413782DOID:6419 (is_implicated_in)
Diseasehuman Chorionic Gonadotropin measurement

TRPM4 NR0B1

5.28e-0413782EFO_0008156
DiseaseSitus ambiguus

PKD1L1 CFC1

7.08e-0415782C0266642
DiseaseEndometrioma

CFD LAMB1 NR4A1 TACSTD2

8.90e-04161784C0269102
DiseaseEndometriosis

CFD LAMB1 NR4A1 TACSTD2

8.90e-04161784C0014175
Diseasebacteriemia

CBLN2 MAGI3

9.14e-0417782EFO_0003033
Diseasetooth agenesis

THSD7B EDA

1.54e-0322782EFO_0005410
DiseaseHuntington's disease (is_implicated_in)

HAP1 MAP3K5

1.68e-0323782DOID:12858 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
GRARGGCPGGEATLS

BTF3

16

P20290
CLSPGCDGILGSGRR

ADAMTSL4

456

Q6UY14
CDGILGSGRRPDGCG

ADAMTSL4

461

Q6UY14
GSGRRPDGCGVCGGD

ADAMTSL4

466

Q6UY14
PGVGGLRCDRCEPGF

AGRN

816

O00468
GEGASARPRCCRNGG

CFC1B

81

P0CG36
LPGCGARARLCGTGA

CELSR1

111

Q9NYQ6
RAECCCGGGRGWGPR

FBN3

2321

Q75N90
CGGGRGWGPRCELCP

FBN3

2326

Q75N90
GEGASARPRCCRNGG

CFC1

81

P0CG37
FGPCSASCGGGLRER

ADAMTS13

751

Q76LX8
GGRRCLSGGCGAPEE

ANO8

541

Q9HCE9
VGGDACLLRGSDPGG

FBXL19

241

Q6PCT2
CRLINPDGSESGCGG

NAGK

131

Q9UJ70
LLLCGGCPRAGGCNE

RAMP3

16

O60896
LARGEAGGCPGLDGL

CDC42BPG

11

Q6DT37
RSGAPGGSEGRCAVC

NR4A1

256

P22736
RDSCKGDSGGPLVCG

CFD

201

P00746
GRLREEPGGGTCCVV

MAGI3

46

Q5TCQ9
PCGALERGAGLGLFC

GFI1

141

Q99684
GELRGGTERGPGRCA

MEPCE

41

Q7L2J0
GCGCGSFRRLGSGCG

KRTAP19-3

26

Q7Z4W3
PGDTSGGCRCRVNGI

RBCK1

486

Q9BYM8
GAGGLLRCLGCRGFL

LONRF1

116

Q17RB8
GGLGPCGKCQEGLEG

HR

336

O43593
EGLGGCGRILPSSGR

PERCC1

51

A0A1W2PR82
SCGGRAGGRCGPGLV

IGFBPL1

76

Q8WX77
GDPRAGGSCFRECGG

MEGF8

1251

Q7Z7M0
GCGRLLRGPESCSLG

MEGF8

2106

Q7Z7M0
GERKCGGPGCGGLVT

LAMB1

1421

P07942
PGGEAGGGHLCCSRR

LDLRAD1

21

Q5T700
RGGCSGLLRCGKGTT

ARSA

291

P15289
GGCGLGEPGSALERR

EGR4

21

Q05215
PRGALDQLCGAGGLC

LAMA5

636

O15230
DQLCGAGGLCRCRPG

LAMA5

641

O15230
LGSGALEDRCGRCGG

ADAMTSL5

181

Q6ZMM2
CGGGARQRTRGCSDP

HMCN1

4716

Q96RW7
GCSCGSDPGVGRAGL

NR0B1

106

P51843
RPGEGGGRERCLRCG

MON1A

31

Q86VX9
CSRGGERGPGGASNC

GATA6

46

Q92908
APRERGSQGCGCGGA

EDA

16

Q92838
SCRSVPTLRGDGGGG

CACNA1G

281

O43497
AGSCCLGAEGGADPR

DGKI

76

O75912
LGRCCAGSRLGPGDP

HAP1

6

P54257
ALREPGGCGSCLGVA

CBLN2

21

Q8IUK8
PGSGGGGCCVVLRLR

C2CD4D

251

B7Z1M9
GAGPGGRGALCLLAE

CCN5

81

O76076
LGRACGCAPGAAGGS

CYP26C1

331

Q6V0L0
DQGLSPCCGDGGARG

FRMD6-AS1

251

P0C7T7
ELLGCGCGAGGRLPG

FBXO24

431

O75426
IGAGLGGGLCRRCSA

KCTD5

16

Q9NXV2
GGGLCRRCSAGLGAL

KCTD5

21

Q9NXV2
GRGSCQGDSGGPLVC

KLK9

196

Q9UKQ9
AAAGGPGAGCVGLCR

C16orf95

26

Q9H693
EGGARGCCLRLDMGG

EMILIN3

446

Q9NT22
LGSDARPAFGGGVCC

DDHD1

26

Q8NEL9
EPGRTGCFPCGGGLL

SCUBE1

711

Q8IWY4
GPGGCGTREDCVLSL

PKD1L1

2431

Q8TDX9
CGPREFRCGGDGGGA

LRP8

206

Q14114
FRCGGDGGGACIPER

LRP8

211

Q14114
FCTIPEGGICRRGGA

MAP3K5

21

Q99683
GPGRAGTDCALDCGS

NTMT2

111

Q5VVY1
GGARSCRRGAPGGAC

MIDN

6

Q504T8
CRRGAPGGACELGPA

MIDN

11

Q504T8
RAVCPAGGEAGLGGC

HIC2

216

Q96JB3
GLQPCSGGTDCELGR

SSPOP

2606

A2VEC9
PDGPGGRCQCRALGS

TACSTD2

46

P09758
CSLLGPAAGRCGGDL

PIK3R6

256

Q5UE93
GRPDRVPGGICGCGS

MYCBP2

786

O75592
CRELGCGGALAAPGG

SSC5D

236

A1L4H1
GCGGGEQALRDCPRS

SSC5D

266

A1L4H1
ACRELGCGGALAAPG

SSC5D

341

A1L4H1
EGPRAGSCCLSPGGR

MRTFA

501

Q969V6
GSCCLSPGGRAELEG

MRTFA

506

Q969V6
GGPGAGKRLCAICGD

RXRB

196

P28702
SGPCRNGGTCKEAGG

SNED1

586

Q8TER0
AGPGRSGEPCGCGLR

CHRNB2

411

P17787
VACDRPRGCKGLGLG

RNF31

321

Q96EP0
CRGCSARLLPGLAGG

TTC19

21

Q6DKK2
LPDCGQLRGEGEGLC

ZNF513

286

Q8N8E2
VRCGGPGDASPRGCG

WEE1

141

P30291
TVSCGGDGRGERGLP

TULP2

96

O00295
RGGRDSCQGDSGGPL

TMPRSS13

501

Q9BYE2
PTGGGTGGASGCRRC

ZFHX2

1661

Q9C0A1
GGSEGGCPRGSPVRC

SDF2L1

86

Q9HCN8
ACREAGCGPALGATG

SSC4D

381

Q8WTU2
GSDGPRKRGLCVLCG

PSTK

11

Q8IV42
GSPGGVAGICSCDGR

PFAS

1276

O15067
DCGTRACPGDCRGRG

TNXB

491

P22105
PGFTGEDCGSRRCPG

TNXB

516

P22105
LALPGGRLGCGEAGS

nan

121

Q8N9P0
RCTGDCGPGGVQSRA

THSD7B

51

Q9C0I4
RQSGRPGCCGGRCGG

TRPM4

751

Q8TD43
GGAERGRPGLCTPQC

TYSND1

96

Q2T9J0
DGGRRGLVCGVCGGA

ZFTA

431

C9JLR9
GERAGLGGTGCSCKP

ZBED4

56

O75132