Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix constituent conferring elasticity	LAMC1 ELN	2.18e-04	12	37	2	GO:0030023
GeneOntologyMolecularFunction	structural molecule activity conferring elasticity	LAMC1 ELN	3.00e-04	14	37	2	GO:0097493
GeneOntologyCellularComponent	nuclear matrix	SMARCC2 SRRM1 SF3B1 MATR3	1.07e-04	140	37	4	GO:0016363
GeneOntologyCellularComponent	nuclear periphery	SMARCC2 SRRM1 SF3B1 MATR3	2.31e-04	171	37	4	GO:0034399
Domain	Vinculin/catenin	VCL TLN1	7.97e-05	7	37	2	IPR006077
Domain	EGF_LAM_2	ATRN LAMC1	1.60e-03	30	37	2	PS50027
Domain	EGF_LAM_1	ATRN LAMC1	1.60e-03	30	37	2	PS01248
Domain	Laminin_EGF	ATRN LAMC1	2.18e-03	35	37	2	PF00053
Domain	EGF_Lam	ATRN LAMC1	2.18e-03	35	37	2	SM00180
Domain	Laminin_EGF	ATRN LAMC1	2.57e-03	38	37	2	IPR002049
Domain	HTH_motif	PHOX2A EN1	8.24e-03	69	37	2	IPR000047
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_IPAB_C_D_TO_ITGA_B_TALIN_VINCULIN_SIGNALING_PATHWAY	VCL TLN1	1.78e-04	9	32	2	M47725
Pathway	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2	MAGED2 VCL TLN1 VEGFB	2.03e-04	130	32	4	MM15455
Pathway	REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2	MAGED2 VCL TLN1 VEGFB	2.16e-04	132	32	4	M724
Pathway	WP_SIDS_SUSCEPTIBILITY_PATHWAYS	PHOX2A DEAF1 EN1	3.17e-04	59	32	3	MM15838
Pathway	WP_FOCAL_ADHESION	LAMC1 VCL TLN1 VEGFB	8.06e-04	187	32	4	MM15913
Pathway	BIOCARTA_RHO_PATHWAY	VCL TLN1	9.25e-04	20	32	2	MM1476
Pathway	WP_FOCAL_ADHESION	LAMC1 VCL TLN1 VEGFB	1.02e-03	199	32	4	M39402
Pathway	KEGG_FOCAL_ADHESION	LAMC1 VCL TLN1 VEGFB	1.02e-03	199	32	4	M7253
Pathway	BIOCARTA_RHO_PATHWAY	VCL TLN1	1.02e-03	21	32	2	M1001
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	SRRM1 RPL14 SF3B1 RPL4 CDK13 MATR3 PHC1	9.97e-09	259	37	7	30404004
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	SMARCC2 LAMC1 RPL14 SF3B1 MAGED2 ZNF804A CHMP2A RPL4 MATR3 TLN1	1.34e-08	847	37	10	35235311
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SMARCC2 ITM2C STUM RPL14 ALDH1L1 SF3B1 GAP43 RPL4 MATR3 VCL TLN1	1.75e-07	1431	37	11	37142655
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	WBP2 NDFIP2 IRF2BPL ZNF804A SH2B1 TLN1 APC2	3.14e-07	430	37	7	35044719
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	WBP2 SMARCC2 SRRM1 RPL14 SF3B1 RPL4 TTLL11 MATR3 VCL TLN1	4.88e-07	1247	37	10	27684187
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	WBP2 SMARCC2 SRRM1 SF3B1 RPL4	6.20e-07	154	37	5	16055720
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	SRRM1 RPL14 SF3B1 MAGED2 MATR3 VCL TLN1	6.30e-07	477	37	7	31300519
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	SMARCC2 SRRM1 RPL14 SF3B1 MAGED2 RPL4 MATR3	7.14e-07	486	37	7	30940648
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	SMARCC2 RPL14 SF3B1 RPL4 MATR3 VCL TLN1	7.96e-07	494	37	7	26831064
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	SMARCC2 SRRM1 RPL14 SF3B1 CDK13 VCL TLN1	9.34e-07	506	37	7	30890647
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	SRRM1 RPL14 SF3B1 RPL4 MATR3 VCL	1.00e-06	317	37	6	30997501
Pubmed	Vinculin head-tail interaction defines multiple early mechanisms for cell substrate rigidity sensing.	VCL TLN1	1.10e-06	2	37	2	27169142
Pubmed	Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions.	VCL TLN1	1.10e-06	2	37	2	24452377
Pubmed	Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.	VCL TLN1	1.10e-06	2	37	2	15728584
Pubmed	Actomyosin-dependent formation of the mechanosensitive talin-vinculin complex reinforces actin anchoring.	VCL TLN1	1.10e-06	2	37	2	24452080
Pubmed	The activity of the vinculin binding sites in talin is influenced by the stability of the helical bundles that make up the talin rod.	VCL TLN1	1.10e-06	2	37	2	16407302
Pubmed	Structural basis for amplifying vinculin activation by talin.	VCL TLN1	1.10e-06	2	37	2	15070891
Pubmed	Dystrophin-glycoprotein complex and vinculin-talin-integrin system in human adult cardiac muscle.	VCL TLN1	1.10e-06	2	37	2	19148538
Pubmed	Vinculins interaction with talin is essential for mammary epithelial differentiation.	VCL TLN1	1.10e-06	2	37	2	31804547
Pubmed	A cell-based splicing reporter system to identify regulators of cis-splicing between adjacent genes.	SRRM1 SF3B1	1.10e-06	2	37	2	30590765
Pubmed	The Transcription Factor Deaf1 Modulates Engrailed-1 Expression to Regulate Skin Appendage Fate.	DEAF1 EN1	1.10e-06	2	37	2	31145909
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SMARCC2 SRRM1 LAMC1 RPL14 SF3B1 MAGED2 CHMP2A CDK13 MATR3 TLN1	1.15e-06	1371	37	10	36244648
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SMARCC2 SRRM1 IRF2BPL DEAF1 SF3B1 MAGED2 CDK13 MATR3	1.27e-06	774	37	8	15302935
Pubmed	Increased talin-vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections.	VCL TLN1	3.30e-06	3	37	2	32238906
Pubmed	RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.	VCL TLN1	3.30e-06	3	37	2	23389036
Pubmed	Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study.	VCL TLN1	3.30e-06	3	37	2	27816808
Pubmed	Talin dissociates from RIAM and associates to vinculin sequentially in response to the actomyosin force.	VCL TLN1	3.30e-06	3	37	2	32561773
Pubmed	A mouse homeo box-containing gene maps near a developmental mutation.	LAMC1 EN1	3.30e-06	3	37	2	2882954
Pubmed	The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin.	VCL TLN1	3.30e-06	3	37	2	16407299
Pubmed	Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion.	VCL TLN1	3.30e-06	3	37	2	15494027
Pubmed	WAVE2 regulates high-affinity integrin binding by recruiting vinculin and talin to the immunological synapse.	VCL TLN1	3.30e-06	3	37	2	17591693
Pubmed	Vinculin controls talin engagement with the actomyosin machinery.	VCL TLN1	3.30e-06	3	37	2	26634421
Pubmed	Central region of talin has a unique fold that binds vinculin and actin.	VCL TLN1	3.30e-06	3	37	2	20610383
Pubmed	Vinculin and talin: focus on the myocardium.	VCL TLN1	3.30e-06	3	37	2	19952892
Pubmed	Focal adhesion proteins talin-1 and vinculin negatively affect paxillin phosphorylation and limit retroviral infection.	VCL TLN1	3.30e-06	3	37	2	21763488
Pubmed	Dual role of vinculin in barrier-disruptive and barrier-enhancing endothelial cell responses.	VCL TLN1	3.30e-06	3	37	2	26923917
Pubmed	Vinculin controls focal adhesion formation by direct interactions with talin and actin.	VCL TLN1	3.30e-06	3	37	2	18056416
Pubmed	CDK12/13 promote splicing of proximal introns by enhancing the interaction between RNA polymerase II and the splicing factor SF3B1.	SF3B1 CDK13	3.30e-06	3	37	2	37026485
Pubmed	Coupling of β2 integrins to actin by a mechanosensitive molecular clutch drives complement receptor-mediated phagocytosis.	VCL TLN1	3.30e-06	3	37	2	31659275
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	WBP2 SMARCC2 RPL14 SF3B1 MAGED2 RPL4 MATR3	3.39e-06	615	37	7	31048545
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	RPL14 SF3B1 MAGED2 RPL4 MATR3	3.66e-06	221	37	5	29991511
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	SMARCC2 SRRM1 SF3B1 MAGED2 CHMP2A TLN1	4.00e-06	403	37	6	35253629
Pubmed	Functional analysis of secreted and transmembrane proteins critical to mouse development.	ATRN LAMC1 ELN	4.88e-06	31	37	3	11431694
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	SMARCC2 RPL14 SF3B1 PIGR RPL4 MATR3 TLN1	4.98e-06	652	37	7	31180492
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SMARCC2 SRRM1 RPL14 SF3B1 RPL4 VCL TLN1	5.03e-06	653	37	7	22586326
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	SRRM1 RPL14 SF3B1 MAGED2 RPL4 CDK13 MATR3	5.13e-06	655	37	7	35819319
Pubmed	Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.	RPL14 SF3B1 RPL4 MATR3	5.57e-06	109	37	4	29511296
Pubmed	Nuclear organization of nucleotide excision repair is mediated by RING1B dependent H2A-ubiquitylation.	RPL14 SF3B1 RPL4 MATR3	6.20e-06	112	37	4	28416769
Pubmed	Molecular interactions of N-RAP, a nebulin-related protein of striated muscle myotendon junctions and intercalated disks.	VCL TLN1	6.60e-06	4	37	2	10320340
Pubmed	Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly.	VCL TLN1	6.60e-06	4	37	2	16000373
Pubmed	Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins.	VCL TLN1	6.60e-06	4	37	2	9054445
Pubmed	Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation.	VCL TLN1	6.60e-06	4	37	2	20308429
Pubmed	Vinculin regulates assembly of talin: β3 integrin complexes.	VCL TLN1	6.60e-06	4	37	2	24446374
Pubmed	Structural dynamics of alpha-actinin-vinculin interactions.	VCL TLN1	6.60e-06	4	37	2	15988023
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	ATRN LAMC1 ITM2C ALDH1L1 PIGR CHMP2A VCL TLN1	9.38e-06	1016	37	8	19056867
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SMARCC2 SRRM1 LAMC1 ITM2C RPL14 SF3B1 MATR3 TLN1	9.93e-06	1024	37	8	24711643
Pubmed	Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.	VCL TLN1	1.10e-05	5	37	2	7534286
Pubmed	Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.	RPL14 CHMP2A RPL4 MATR3 VCL TLN1	1.23e-05	491	37	6	22623428
Pubmed	Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile.	VCL TLN1	1.65e-05	6	37	2	22925892
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	SMARCC2 RPL14 ALDH1L1 RPL4 MATR3 VCL TLN1	1.98e-05	807	37	7	30575818
Pubmed	Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells.	SMARCC2 SRRM1 RPL14 MATR3	2.12e-05	153	37	4	28225217
Pubmed	UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.	RPL14 MAGED2 RPL4 CDK13	2.23e-05	155	37	4	34921745
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SRRM1 RPL14 SF3B1 MAGED2 RPL4 MATR3 VCL TLN1	2.28e-05	1149	37	8	35446349
Pubmed	Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.	VCL TLN1	2.30e-05	7	37	2	23266827
Pubmed	Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.	SMARCC2 SRRM1 RPL14 RPL4 MATR3	2.65e-05	333	37	5	36779763
Pubmed	Large-scale concatenation cDNA sequencing.	CXXC5 STUM SF3B1 ZNF804A COG7 MATR3	2.79e-05	568	37	6	9110174
Pubmed	A "double adaptor" method for improved shotgun library construction.	CXXC5 STUM SF3B1 ZNF804A COG7 MATR3	2.96e-05	574	37	6	8619474
Pubmed	β2 integrin adhesion complexes maintain the integrity of HIV-1 assembly compartments in primary macrophages.	VCL TLN1	3.07e-05	8	37	2	22017400
Pubmed	Extracellular-matrix gene expression during mouse submandibular gland development.	LAMC1 ELN	3.07e-05	8	37	2	9382709
Pubmed	beta-Dystroglycan modulates the interplay between actin and microtubules in human-adhered platelets.	VCL TLN1	3.07e-05	8	37	2	18341635
Pubmed	Mice without transcription factor KLF7 provide new insight into olfactory bulb development.	KLF7 GAP43	3.07e-05	8	37	2	16814267
Pubmed	Phosphoinositide-specific phospholipase C β 1b (PI-PLCβ1b) interactome: affinity purification-mass spectrometry analysis of PI-PLCβ1b with nuclear protein.	RPL14 SF3B1 RPL4 TLN1	3.14e-05	169	37	4	23665500
Pubmed	The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.	SRRM1 SF3B1 RPL4 MATR3	3.14e-05	169	37	4	23084401
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	SMARCC2 SRRM1 RPL14 SF3B1 RPL4 MATR3	3.83e-05	601	37	6	33658012
Pubmed	Sudden infant death syndrome: case-control frequency differences at genes pertinent to early autonomic nervous system embryologic development.	PHOX2A EN1	3.95e-05	9	37	2	15240857
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	VCL TLN1	3.95e-05	9	37	2	11807098
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	SMARCC2 SRRM1 RPL14 SF3B1 RPL4 MATR3	3.97e-05	605	37	6	28977666
Pubmed	FAM188B enhances cell survival via interaction with USP7.	RPL14 SF3B1 RPL4	4.63e-05	65	37	3	29795372
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	SRRM1 RPL14 KHDC4 RPL4 CDK13 MATR3 TLN1	4.72e-05	925	37	7	28986522
Pubmed	14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.	SMARCC2 SF3B1 MATR3	4.84e-05	66	37	3	23472066
Pubmed	A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection.	PIGR CHMP2A VCL TLN1	4.85e-05	189	37	4	31594818
Pubmed	Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation.	VCL TLN1	4.93e-05	10	37	2	11113628
Pubmed	Assembly of the cochlear gap junction macromolecular complex requires connexin 26.	VCL TLN1	4.93e-05	10	37	2	24590285
Pubmed	A protein interaction landscape of breast cancer.	SMARCC2 SRRM1 RPL14 PIGR RPL4 TLN1	5.15e-05	634	37	6	34591612
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	CXXC5 SRRM1 RPL14 DEAF1 SF3B1 RPL4 CDK13 MATR3	5.30e-05	1294	37	8	30804502
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	RPL14 SF3B1 MAGED2 COG7 RPL4 TLN1	5.33e-05	638	37	6	33239621
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	SRRM1 RPL14 SF3B1 MAGED2 RPL4 CDK13 MATR3	5.55e-05	949	37	7	36574265
Pubmed	Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.	RPL14 RPL4 MATR3 VCL	5.70e-05	197	37	4	32434143
Pubmed	Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase.	RPL14 MAGED2 RPL4	5.78e-05	70	37	3	21726808
Pubmed	En1 is necessary for survival of neurons in the ventral nuclei of the lateral lemniscus.	ALDH1L1 EN1	6.02e-05	11	37	2	26914477
Pubmed	SVEP1 is an endogenous ligand for the orphan receptor PEAR1.	LAMC1 TLN1	6.02e-05	11	37	2	36792666
Pubmed	An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.	RPL14 COG7 MATR3 VCL TLN1	6.10e-05	397	37	5	21319273
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	RPL14 MAGED2 CDK13 VCL TLN1	6.25e-05	399	37	5	37536630
Pubmed	Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation.	RPL14 SF3B1 RPL4 MATR3	6.65e-05	205	37	4	27976729
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	SRRM1 IRF2BPL RPL14 GAP43 CDK13 MATR3	6.70e-05	665	37	6	30457570
Pubmed	A comparative gene map of the horse (Equus caballus).	LAMC1 ELN	7.22e-05	12	37	2	10613847
Pubmed	Identification of genes regulated by transcription factor KLF7 in differentiating olfactory sensory neurons.	KLF7 GAP43	7.22e-05	12	37	2	17123745
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SMARCC2 RPL14 SF3B1 MAGED2 RPL4 MATR3 VCL TLN1	7.24e-05	1353	37	8	29467282
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	SRRM1 RPL14 SF3B1 RPL4 CDK13 MATR3	7.46e-05	678	37	6	30209976
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	LAMC1 RPL14 PIGR MAGED2 RPL4	7.78e-05	418	37	5	35338135
Interaction	SNIP1 interactions	SMARCC2 SRRM1 RPL14 SF3B1 RPL4 CDK13 MATR3	9.30e-06	417	37	7	int:SNIP1
Interaction	ATXN1 interactions	SMARCC2 SRRM1 NDFIP2 IRF2BPL RPL14 EN1 GAP43 ZNF804A CDK13 MATR3	1.24e-05	1039	37	10	int:ATXN1
Interaction	PINK1 interactions	SRRM1 RPL14 SF3B1 MAGED2 MATR3 VCL TLN1 PLIN2	2.59e-05	679	37	8	int:PINK1
Interaction	KCTD13 interactions	SMARCC2 ITM2C STUM RPL14 ALDH1L1 SF3B1 GAP43 RPL4 MATR3 VCL TLN1	2.66e-05	1394	37	11	int:KCTD13
Interaction	EED interactions	SMARCC2 SRRM1 LAMC1 RPL14 SF3B1 PIGR CHMP2A RPL4 MATR3 TLN1 PHC1	3.72e-05	1445	37	11	int:EED
Interaction	MTF1 interactions	RPL14 SF3B1 RPL4 MATR3	7.47e-05	123	37	4	int:MTF1
Interaction	BAP1 interactions	SRRM1 RPL14 ALDH1L1 SF3B1 EN1 MAGED2 RPL4 MATR3 VCL TLN1	9.21e-05	1314	37	10	int:BAP1
Interaction	WWP2 interactions	WBP2 SMARCC2 NDFIP2 RPL14 SF3B1 MAGED2 RPL4 MATR3	1.16e-04	840	37	8	int:WWP2
Interaction	YAP1 interactions	WBP2 SMARCC2 NDFIP2 RPL14 RPL4 MATR3 VCL TLN1 APC2	1.25e-04	1095	37	9	int:YAP1
Interaction	REST interactions	SMARCC2 RPL14 SF3B1 RPL4 MATR3	1.37e-04	274	37	5	int:REST
Interaction	BRD7 interactions	SMARCC2 SRRM1 RPL14 SF3B1 MAGED2 RPL4 MATR3	1.37e-04	637	37	7	int:BRD7
Interaction	RNF2 interactions	SMARCC2 RPL14 SF3B1 MAGED2 RPL4 CDK13 MATR3 PHC1	1.43e-04	866	37	8	int:RNF2
Interaction	PTPN6 interactions	SMARCC2 SRRM1 RPL14 MAGED2 RPL4	1.46e-04	278	37	5	int:PTPN6
Interaction	PRPF40A interactions	SMARCC2 SRRM1 SF3B1 RPL4 CDK13 VCL	1.48e-04	446	37	6	int:PRPF40A
Interaction	RPA4 interactions	RPL14 SF3B1 RPL4 CDK13 MATR3 TLN1	1.59e-04	452	37	6	int:RPA4
Interaction	RC3H2 interactions	SRRM1 RPL14 SF3B1 RPL4 CDK13 MATR3 VCL	1.83e-04	667	37	7	int:RC3H2
Interaction	CHMP4C interactions	RPL14 SF3B1 MAGED2 CHMP2A RPL4 MATR3 VCL	2.19e-04	687	37	7	int:CHMP4C
Interaction	RNF113A interactions	SRRM1 RPL14 SF3B1 MAGED2 RPL4 CDK13 MATR3	2.29e-04	692	37	7	int:RNF113A
Interaction	ACTC1 interactions	SMARCC2 SRRM1 RPL14 SF3B1 CDK13 VCL TLN1	2.33e-04	694	37	7	int:ACTC1
Interaction	CHMP4B interactions	WBP2 SRRM1 RPL14 SF3B1 CHMP2A RPL4 MATR3	3.09e-04	727	37	7	int:CHMP4B
Interaction	MINDY4 interactions	RPL14 SF3B1 RPL4	3.24e-04	73	37	3	int:MINDY4
Interaction	SIRT7 interactions	SMARCC2 SRRM1 RPL14 SF3B1 RPL4 VCL TLN1	3.55e-04	744	37	7	int:SIRT7
Interaction	EIF2AK4 interactions	SRRM1 EN1 MATR3	3.79e-04	77	37	3	int:EIF2AK4
Interaction	FOXO1 interactions	SF3B1 PIGR RPL4 VCL TLN1	4.08e-04	347	37	5	int:FOXO1
Interaction	EEF1A1 interactions	SRRM1 LAMC1 RPL14 MAGED2 RPL4 MATR3 TLN1	4.11e-04	762	37	7	int:EEF1A1
Interaction	E2F4 interactions	SMARCC2 SRRM1 SF3B1 MAGED2 CHMP2A TLN1	4.13e-04	540	37	6	int:E2F4
Interaction	SRRM1 interactions	SMARCC2 SRRM1 RPL14 SF3B1 RPL4	4.13e-04	348	37	5	int:SRRM1
Interaction	B3GNT2 interactions	LAMC1 RPL14 PIGR MAGED2 RPL4 TLN1	4.21e-04	542	37	6	int:B3GNT2
Interaction	ZCCHC7 interactions	RPL14 RPL4 PHC1	4.40e-04	81	37	3	int:ZCCHC7
Interaction	ITGA4 interactions	RPL14 CHMP2A RPL4 MATR3 VCL TLN1	4.42e-04	547	37	6	int:ITGA4
Interaction	ZEB1 interactions	RPL14 DEAF1 EN1 RPL4	4.81e-04	200	37	4	int:ZEB1
Interaction	RBM39 interactions	SRRM1 IRF2BPL RPL14 SF3B1 MAGED2 KHDC4 RPL4 MATR3	5.02e-04	1042	37	8	int:RBM39
Interaction	MOB3C interactions	RPL14 MAGED2 CDK13 VCL TLN1	5.07e-04	364	37	5	int:MOB3C
Interaction	NOVA1 interactions	SMARCC2 MATR3	5.50e-04	19	37	2	int:NOVA1
Interaction	NRAP interactions	VCL TLN1	5.50e-04	19	37	2	int:NRAP
Cytoband	5q31.2	CXXC5 MATR3	2.36e-04	28	37	2	5q31.2
GeneFamily	L ribosomal proteins	RPL14 RPL4	2.25e-03	51	25	2	729
Coexpression	GAUTAM_EYE_CORNEA_FIBROBLASTS	LAMC1 ITM2C MAGED2 RPL4 TLN1 PLIN2	1.12e-07	165	37	6	M43617
Coexpression	TABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING	CXXC5 WBP2 IRF2BPL ITM2C ELN KLF7 RPL4 DGAT1 PLIN2	3.49e-07	685	37	9	MM3782
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP	CXXC5 ITM2C DGAT1 VCL PLIN2	8.79e-06	200	37	5	M8505
Coexpression	LAKE_ADULT_KIDNEY_C18_COLLECTING_DUCT_PRINCIPAL_CELLS_MEDULLA	CXXC5 ITM2C RPL14 SF3B1 RPL4	8.56e-05	322	37	5	M39237
Coexpression	TABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING	WBP2 IRF2BPL SF3B1 KLF7 CHMP2A DGAT1 TLN1 PLIN2	9.15e-05	1055	37	8	MM3677
Coexpression	TABULA_MURIS_SENIS_BRAIN_NON_MYELOID_BRAIN_PERICYTE_AGEING	CXXC5 WBP2 RPL14 KLF7 CHMP2A TLN1 VEGFB	9.35e-05	778	37	7	MM3686
Coexpression	KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN	LAMC1 ITM2C KLF7 ZNF804A VCL	1.06e-04	337	37	5	M13206
Coexpression	LAKE_ADULT_KIDNEY_C10_THIN_ASCENDING_LIMB	CXXC5 ITM2C RPL14 SF3B1 RPL4	1.32e-04	353	37	5	M39229
Coexpression	TABULA_MURIS_SENIS_BRAIN_MYELOID_MICROGLIAL_CELL_AGEING	WBP2 ITM2C RPL14 CHMP2A RPL4	1.37e-04	356	37	5	MM3684
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	CXXC5 LAMC1 IRF2BPL DEAF1 KLF7 VCL TLN1	1.54e-04	843	37	7	M2356
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP	SF3B1 KLF7 SH2B1 PHC1	1.75e-04	199	37	4	M4526
Coexpression	GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN	NDFIP2 ALDH1L1 TTLL11 PHC1	1.78e-04	200	37	4	M330
Coexpression	GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP	CXXC5 ATRN ALDH1L1 DGAT1	1.78e-04	200	37	4	M7980
Coexpression	GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_UP	CXXC5 IRF2BPL VCL VEGFB	1.78e-04	200	37	4	M9748
Coexpression	GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_DN	LAMC1 PHOX2A KLF7 TLN1	1.78e-04	200	37	4	M7415
Coexpression	TABULA_MURIS_SENIS_KIDNEY_KIDNEY_COLLECTING_DUCT_PRINCIPAL_CELL_AGEING	SRRM1 IRF2BPL ITM2C RPL14 CHMP2A	2.20e-04	394	37	5	MM3724
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_DN	CXXC5 ITM2C EN1 MAGED2 VEGFB	2.30e-04	398	37	5	M7514
Coexpression	SWEET_KRAS_ONCOGENIC_SIGNATURE	LAMC1 RPL14 PLIN2	2.70e-04	89	37	3	M10573
Coexpression	RAO_BOUND_BY_SALL4	IRF2BPL MATR3 PHC1 PLIN2	2.84e-04	226	37	4	M2521
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_DN	CXXC5 ITM2C EN1 MAGED2 VEGFB	2.98e-04	421	37	5	MM985
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A STUM GAP43 ZNF804A APC2	3.41e-07	176	37	5	04dad262929581872e5bbc66cd8182c963e7e52f
ToppCell	Cerebellum-Endothelial\|Cerebellum / BrainAtlas - Mouse McCarroll V32	LAMC1 RPL14 ELN RPL4 TLN1	5.66e-07	195	37	5	2192fd9b4682054776f0716933aed5a4a9412657
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 PHOX2A STUM GAP43 APC2	6.10e-07	198	37	5	50504a3871f76d6a5b439a56450d7770f4501eb0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 PHOX2A GAP43 ZNF804A APC2	6.10e-07	198	37	5	6483d412b6c0aab58b3348f99231caa5daf65025
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC1 ITM2C ELN MAGED2 VCL	6.25e-07	199	37	5	36c1deac7ef0f9ebde6b2f7a63f7daa03d8c139a
ToppCell	E15.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PHOX2A ALDH1L1 GAP43 ZNF804A	1.23e-05	172	37	4	a8b33d8ebc56e442a2ad6ac7dafd0c887571bd95
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STUM PIGR MAGED2 VCL	1.29e-05	174	37	4	3f0a5ce074675d57d479fa069385a1b3071e884e
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITM2C RPL14 MAGED2 RPL4	1.35e-05	176	37	4	3027d34fd663c8a08544d469183dc45138916749
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STUM MAGED2 GAP43 APC2	1.44e-05	179	37	4	bfc226bcf0b93525992344f968268a261d86fcbf
ToppCell	facs-Bladder-nan-24m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WBP2 RPL14 RPL4 VEGFB	1.44e-05	179	37	4	fc9f44fb81da0d381a5141a95a005e66a0be28cc
ToppCell	wk_15-18-Epithelial-PNS-KCNIP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	1.44e-05	179	37	4	e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STUM MAGED2 GAP43 APC2	1.44e-05	179	37	4	36ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCell	facs-Bladder-nan-24m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WBP2 RPL14 RPL4 VEGFB	1.44e-05	179	37	4	9152d92bb96e65d43de54e933494f0d08ae02c4f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 PHOX2A STUM GAP43	1.54e-05	182	37	4	be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 ZNF804A APC2	1.61e-05	184	37	4	abb61e744a9031e0c91eb560a8f486a0ca5a01cc
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	1.68e-05	186	37	4	2fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	1.68e-05	186	37	4	cf96f880e6e22189593ce1357c55e65c34644559
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A STUM GAP43 APC2	1.75e-05	188	37	4	bd091503f580dedab40e0996273101285d24b586
ToppCell	wk_15-18-Epithelial-PNS-PCP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	1.79e-05	189	37	4	22c927d2691b867fbdee1fbee042a6d3f7eadd7d
ToppCell	ASK440-Immune-Mast_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	NDFIP2 ITM2C RPL14 RPL4	1.79e-05	189	37	4	72a19b20cb0f7283afe5f85d62a21cff69fd78d0
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A STUM GAP43 APC2	1.79e-05	189	37	4	cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	1.79e-05	189	37	4	de06ef69f3f97b3f21dc269eb6965da9b2f6e3f8
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHOX2A STUM COG7 VCL	1.82e-05	190	37	4	1d8e169d2448a34180c415843bb49aa45ed540c5
ToppCell	11.5-Airway-Epithelial-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	PHOX2A GAP43 ZNF804A APC2	1.90e-05	192	37	4	a77d3692ff02ef7e066a9bd9e22725055a25c4d4
ToppCell	Healthy_donor-B_intermediate\|World / disease group, cell group and cell class (v2)	CXXC5 ITM2C ZNF804A VEGFB	1.90e-05	192	37	4	f77007b284e11f8654ad599eef929df7c6c4ebf0
ToppCell	wk_08-11-Epithelial-PNS-KCNIP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	1.90e-05	192	37	4	53642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCell	wk_15-18-Epithelial-PNS\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	1.94e-05	193	37	4	ca65f8f93058ad50d89e69e06c10deeb46dbfc87
ToppCell	droplet-Bladder-nan-24m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BPL RPL14 RPL4 PLIN2	1.94e-05	193	37	4	9d7bc71c4ae871aad057d3beb6e06c929ae17203
ToppCell	CV-Severe-6\|Severe / Virus stimulation, Condition and Cluster	CXXC5 WBP2 VCL TLN1	1.98e-05	194	37	4	d33be6ed1de907aeea0c2dce09796556b8efdd4e
ToppCell	18-Airway-Epithelial-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	PHOX2A GAP43 ZNF804A APC2	1.98e-05	194	37	4	d3c90e1f1228f8ba0ba56105c6cf4f302c388f28
ToppCell	CV-Severe-6\|CV / Virus stimulation, Condition and Cluster	CXXC5 WBP2 VCL TLN1	2.02e-05	195	37	4	69095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCell	(2)_5-FU\|World / Stress and Cell class	LAMC1 ITM2C MAGED2 VCL	2.02e-05	195	37	4	e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A STUM GAP43 APC2	2.02e-05	195	37	4	5a6a5048af638872700b76b7c71a8fa3fb8d3772
ToppCell	MS-plasma\|MS / Condition, Cell_class and T cell subcluster	CXXC5 LAMC1 ITM2C GAP43	2.02e-05	195	37	4	de866c0eaec36d94a3101eb9f949ca9544207f33
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RPL14 ELN MAGED2 RPL4	2.02e-05	195	37	4	def0a3fb36eec6fbb08e1323baf2b22b28bf751a
ToppCell	MS-plasma-\|MS / Condition, Cell_class and T cell subcluster	CXXC5 LAMC1 ITM2C GAP43	2.02e-05	195	37	4	b0a51dea06899e6a4477c3436c85e114cd8f6214
ToppCell	control-Others-CD34+_GATA2+_cells\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CXXC5 ITM2C RPL14 RPL4	2.06e-05	196	37	4	25994ca143701c72d2f84a3b6d348fcfa1d26a54
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITM2C ELN GAP43 APC2	2.06e-05	196	37	4	45d1c0a962c4221c17393ee5566961d1deebf442
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	ITM2C KHDC4 MATR3 VCL	2.06e-05	196	37	4	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	wk_08-11-Epithelial-PNS\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	2.10e-05	197	37	4	ce3f9feb6935f0e9daf13673b0a0d6e92817e187
ToppCell	(2)_NK/T-(22)_CD8+_T_cell-(221)_CD8+_Naive_T_cell\|(22)_CD8+_T_cell / immune cells in Peripheral Blood (logTPM normalization)	ITM2C RPL14 KLF7 RPL4	2.10e-05	197	37	4	ac77bcd7548db40147bf55dbf0ce86ed0b6a86da
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ITM2C ELN APC2 VEGFB	2.10e-05	197	37	4	965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCell	mild-Others-CD34+_GATA2+_cells\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CXXC5 ITM2C RPL14 RPL4	2.10e-05	197	37	4	a375edbc885ae069f9abcd8d5886fdaa8913f83d
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-B_lymphocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CXXC5 ITM2C RPL14 RPL4	2.10e-05	197	37	4	e9327b133dab5f6a187cd8713f07205c948ec600
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 ZNF804A APC2	2.10e-05	197	37	4	5593721407f61fc5bc3f2f8bf8fa2604c4e29565
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ITM2C ELN APC2 VEGFB	2.10e-05	197	37	4	3f088eb29197bc575400d6dafd8083e69e4a149f
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A STUM GAP43 APC2	2.10e-05	197	37	4	a07e1a9b95c9f8a09452cbfe5a9f06648f66e29e
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 ZNF804A APC2	2.10e-05	197	37	4	a1ae1aa797762a3768e14434c7e5cd19c595ecb3
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 ZNF804A APC2	2.10e-05	197	37	4	c220102fadbb7ba385a61704a144e0b814cb5c46
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A2_(IPAN/IN)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A STUM GAP43 APC2	2.10e-05	197	37	4	f7eaac1c321710a55e09ffb047a7db2baf7b7e28
ToppCell	11.5-Airway-Mesenchymal\|Airway / Age, Tissue, Lineage and Cell class	ITM2C RPL14 ELN RPL4	2.14e-05	198	37	4	fe08709d043d927988b1bb262c766b0b572fc927
ToppCell	11.5-Distal-Mesenchymal\|Distal / Age, Tissue, Lineage and Cell class	ITM2C RPL14 ELN RPL4	2.14e-05	198	37	4	5c606d881f151404287d9b43c9490e9bb486ef54
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CXXC5 ITM2C GAP43 APC2	2.14e-05	198	37	4	01d563ccdc0da02dac04169e713844fecb4233a1
ToppCell	wk_08-11-Epithelial-PNS-TM4SF4+_CHODL+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A APC2	2.14e-05	198	37	4	eb3c389e7452d74e5e15179503e480d6d11ca9ca
ToppCell	facs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRF2BPL MATR3 VCL TLN1	2.14e-05	198	37	4	22559b161e67b49fe8028bfaf861e069063599f5
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CXXC5 ITM2C GAP43 APC2	2.19e-05	199	37	4	6723287924750a2247a07ab6e561066a97b09771
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 PHOX2A GAP43 APC2	2.19e-05	199	37	4	86739a6f5e0fa7448389b97b3c4de41f2a7d7ebd
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC1 ITM2C ELN MAGED2	2.19e-05	199	37	4	84545ced0c792bc77980a50d65e484eab648d47e
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RPL14 PIGR RPL4 PLIN2	2.19e-05	199	37	4	df157604a7e2b6e7fa2d21660ca749a3552b945c
ToppCell	COVID-19_Mild-PLT_1\|COVID-19_Mild / Disease Group and Platelet Clusters	WBP2 MAGED2 VCL TLN1	2.19e-05	199	37	4	7f32958a73bc6020ea8a0e595ec749bbfe74c1b3
ToppCell	343B-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RPL14 PIGR RPL4 PLIN2	2.19e-05	199	37	4	48626e54ce94b5ea3001fc5d447509a50c073aa4
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CXXC5 PHOX2A GAP43 APC2	2.19e-05	199	37	4	f2410509007d35e948a88f127f613d0119e6a4c4
ToppCell	Mild/Remission-B_intermediate-0\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CXXC5 RPL14 ZNF804A MATR3	2.19e-05	199	37	4	592111591f0f6816fc56620cb555eb48dabf0758
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CXXC5 ITM2C GAP43 APC2	2.19e-05	199	37	4	04e5cfb85c681fd3f4c1151062e4a0f460b55d5f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	CXXC5 LAMC1 ELN TLN1	2.23e-05	200	37	4	5ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCell	critical-Myeloid-Monocyte-derived_DC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL14 PIGR RPL4 VEGFB	2.23e-05	200	37	4	e2d0e635b70f4bc25e1d374d46e63efbb2e2be0f
ToppCell	Kidney\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	CXXC5 ITM2C ALDH1L1 PIGR	2.23e-05	200	37	4	1f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCell	15-Airway-Mesenchymal\|Airway / Age, Tissue, Lineage and Cell class	ITM2C ELN MAGED2 RPL4	2.23e-05	200	37	4	13c4835b98e1bb91c2d04e08cdeaed8eba30b1d9
ToppCell	ASK454-Immune\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	RPL14 RPL4 PLIN2	2.50e-04	148	37	3	1076c69bf2a5e4557aa35643fd9bd86e8610815b
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	NDFIP2 KLF7 EN1	2.91e-04	156	37	3	ffb9249a115ce31f50b99a7a3d40bf48b9d7f2b0
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RPL14 ELN MATR3	2.91e-04	156	37	3	96747447ba7dc2c10079cee44394b19ce60b2f41
ToppCell	facs-Heart-RV-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHOX2A COG7 VEGFB	3.02e-04	158	37	3	2ef43d14ee65d004dc62c12ff209bbe12e4db681
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	WBP2 VCL TLN1	3.20e-04	161	37	3	bfb79277889142133ce86492a808f3083a7547e8
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 APC2	3.20e-04	161	37	3	bb9cb42882aaa4a1ecf9b480c0e7ac302f2c0d5d
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	WBP2 VCL TLN1	3.20e-04	161	37	3	d6f4b0e4e3b2a4e6232a6de3d67b210e24f8c89d
ToppCell	-Hematopoietic_Mast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SRRM1 PLIN2	3.21e-04	32	37	2	ca3d87cac849c1b713acd984626f214f5c8e1433
ToppCell	-Hematopoietic_Mast-Mast_cells-Mast-cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SRRM1 PLIN2	3.21e-04	32	37	2	c6b707107c661f81e5afa945dd62b37a73bfadf9
ToppCell	-Hematopoietic_Mast-Mast_cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SRRM1 PLIN2	3.21e-04	32	37	2	de636b6fbdc9368ef6ce7157acbf84e28330cd94
ToppCell	tumor_Lung-B_lymphocytes-Undetermined\|tumor_Lung / Location, Cell class and cell subclass	STUM RPL14 RPL4	3.43e-04	165	37	3	3d010a66abac3961cc99f20b1459cf0eb0f7510d
ToppCell	mild_COVID-19_(asymptomatic)-B_intermediate\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	STUM ZNF804A MATR3	3.49e-04	166	37	3	8de8f388f24436b84e19ef460476fdbda4d16abf
ToppCell	IIF-Lymphocyte-T_NK-CD8_TCM\|IIF / Disease, Lineage and Cell Type	ITM2C RPL14 RPL4	3.49e-04	166	37	3	f3f289eb9fa52abf0226ec711302022a07a6f345
ToppCell	Immune_cells-pro-B\|Immune_cells / Lineage and Cell class	CXXC5 MAGED2 TTLL11	3.88e-04	172	37	3	096636f2589fa56d15942aac96641c16fd5fa78d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	STUM GAP43 ZNF804A	4.01e-04	174	37	3	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A KLF7 APC2	4.01e-04	174	37	3	271c51d220842402975d97c86c9acfdbdf62a32c
ToppCell	Healthy/Control-Plasmablast\|Healthy/Control / Disease group and Cell class	NDFIP2 ITM2C GAP43	4.01e-04	174	37	3	97d19ef3240a1f648c6befaabb9ce45ad469cbce
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STUM PIGR VCL	4.01e-04	174	37	3	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Cortical_neuron\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	WBP2 KLF7	4.07e-04	36	37	2	25fd4cf19f2ed94f99600c18383b17f86bb17ef5
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHOX2A MAGED2 GAP43	4.08e-04	175	37	3	a7310950e8d51b3004ea3aee8ce9948fe8655112
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHOX2A MAGED2 GAP43	4.08e-04	175	37	3	d2ff8fedca9039cbd45cfd9dec88f4edbe7fe4fc
ToppCell	mild-Myeloid-pDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CXXC5 ITM2C VEGFB	4.15e-04	176	37	3	59a9c262c252b7d220a025837922d98e9d6b0a24
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 APC2	4.15e-04	176	37	3	116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	PHOX2A RPL14 RPL4	4.15e-04	176	37	3	2a15437c5f5dbf6398d5ea70050632c24a7dc66c
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 APC2	4.15e-04	176	37	3	bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 APC2	4.15e-04	176	37	3	5b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PHOX2A GAP43 APC2	4.15e-04	176	37	3	3c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN DGAT1 VCL	4.22e-04	177	37	3	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED2 GAP43 APC2	4.22e-04	177	37	3	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	PCW_13-14-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PHOX2A GAP43 ZNF804A	4.22e-04	177	37	3	8c78f7de091f16e86e326a73c9f1429e0232821f
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN DGAT1 VCL	4.22e-04	177	37	3	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGED2 GAP43 APC2	4.22e-04	177	37	3	8684d47a547e2a06496f15e8da0200ecddc431e0
Drug	Lomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; MCF7; HT_HG-U133A	STUM ALDH1L1 GAP43 CDK13 SH2B1 VCL	6.81e-07	195	37	6	3620_UP
Drug	(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; PC3; HT_HG-U133A	PHOX2A STUM ELN ALDH1L1 CDK13 TLN1	6.81e-07	195	37	6	3789_UP
Drug	Withaferin A [5119-48-2]; Up 200; 1uM; PC3; HT_HG-U133A	WBP2 PHOX2A KLF7 ZNF804A VCL	1.07e-05	181	37	5	3819_UP
Drug	Trimethoprim [738-70-5]; Up 200; 13.8uM; MCF7; HT_HG-U133A	PHOX2A PIGR CDK13 TLN1 APC2	1.60e-05	197	37	5	2307_UP
Drug	Procaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A	STUM CDK13 SH2B1 VCL TLN1	1.73e-05	200	37	5	6329_UP
Disease	schizophrenia, intelligence, self reported educational attainment	SF3B1 ZNF804A SH2B1 TTLL11	8.14e-04	346	36	4	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	Intellectual Disability	SMARCC2 DEAF1 KLF7 APC2	2.09e-03	447	36	4	C3714756

Protein segments in the cluster

Peptide	Gene	Start	Entry
KEAASGKADGHAATL	COG7	26	P83436
ARAKAASAGKKASSA	DGAT1	221	O75907
VAAGGKKAEAAASAL	CHMP2A	191	O43633
KKAEAAASALADADA	CHMP2A	196	O43633
RAAEAAKAAEATKAA	CDK13	466	Q14004
AKAAEATKAAEAAAK	CDK13	471	Q14004
ATKAAEAAAKAAKAS	CDK13	476	Q14004
SDKAVKKDGSASAAA	MATR3	696	P43243
ADLKAAAEAAAEAKA	MAGED2	481	Q9UNF1
AAAAVSGSAAAEAKE	ATRN	86	O75882
VALSAKEAAAAAAAA	IRF2BPL	81	Q9H1B7
VATAAAAVTAAGAVK	KLF7	181	O75840
VDKAAAAAAALQAKS	RPL4	351	P36578
AAAAALQAKSDEKAA	RPL4	356	P36578
AAAVAAAAAAAAAKP	EN1	206	Q05925
KAGAADKSAVVAAAA	CXXC5	31	Q7LFL8
AGIKGDKADKASASA	ITM2C	11	Q9NQX7
KAKAAAMAAAAAETS	NDFIP2	191	Q9NV92
KDTSGEAAVAAKAKA	APC2	831	O95996
SAAKQLGLAEAAAVA	DEAF1	6	O75398
APSGALDAAAAVAAK	KHDC4	51	Q7Z7F0
ALGSAAADATEAKNK	LAMC1	1411	P11047
GPQAAAAAAAKAAAK	ELN	251	P15502
PAAAAAAAAAAKAAK	ELN	301	P15502
GVVSPEAAAKAAAKA	ELN	366	P15502
PAAAAAKAAAKAAQF	ELN	486	P15502
GGVAAAAKSAAKVAA	ELN	551	P15502
AAAAAAAKAAAKAAQ	ELN	686	P15502
AAKAAAKAAQFGLVG	ELN	691	P15502
SRAPEVAAAAAAAAK	SH2B1	661	Q9NRF2
AAAATTPAAEDAAAK	GAP43	176	P17677
AAAAALAAAAVKAKH	SMARCC2	861	Q8TAQ2
VDKAVAAAKDAFENG	ALDH1L1	461	O75891
AEAVAAAKAAAKAEA	TTLL11	106	Q8NHH1
AAKAAAKAEAEATAE	TTLL11	111	Q8NHH1
TKGTAAAAAAAAAAK	RPL14	146	P50914
AAAAAAAAAKVPAKK	RPL14	151	P50914
AKAGELKVVNGAAAS	SF3B1	176	O75533
ASAAAALVLKAKSVA	TLN1	676	Q9Y490
GAAAAIEAAAKKLEQ	TLN1	2311	Q9Y490
KDAETAAAAAAVAAA	STUM	6	Q69YW2
HKKEKAVAAAAAAAV	SRRM1	831	Q8IYB3
AASAKGAAGAAGAKK	PHOX2A	151	O14813
GATAEKAAAVGTANK	VCL	641	P18206
AESAAAKKAEADGSG	PHC1	331	P78364
KAAGSRDVSLAKADA	PIGR	566	P01833
AAAAADAAASSVAKG	VEGFB	191	P49765
ANAKGAVTGAKDAVT	PLIN2	106	Q99541
AAAAAAAAAGTFKVL	ZNF804A	1111	Q7Z570
TPAAEAKAAEAAASA	WBP2	216	Q969T9