Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD1 CHD2

4.46e-0437172GO:0140658
GeneOntologyMolecularFunctionhistone binding

RNF8 CHD1 CHD2

1.37e-03265173GO:0042393
GeneOntologyBiologicalProcesssaliva secretion

KCNMA1 CHRM3

7.62e-0517162GO:0046541
GeneOntologyCellularComponentchromatin

WDR76 NFXL1 PRAME CHD1 CHD2 TET1

5.38e-041480166GO:0000785
GeneOntologyCellularComponentsynaptic membrane

KCNMA1 SORCS3 CHRM3 DNM1

8.34e-04583164GO:0097060
GeneOntologyCellularComponentpresynaptic membrane

KCNMA1 CHRM3 DNM1

1.13e-03277163GO:0042734
HumanPhenoAtypical absence seizure

KCNMA1 CHD2 DNM1

6.81e-064653HP:0007270
HumanPhenoEEG with focal sharp slow waves

CHD2 DNM1

5.99e-051352HP:0011195
HumanPhenoEEG with focal epileptiform discharges

KCNMA1 CHD2 DNM1

1.17e-0411853HP:0011185
HumanPhenoPersonality disorder

CHD2 DNM1

1.17e-041852HP:0012075
HumanPhenoStatus epilepticus without prominent motor symptoms

CHD2 DNM1

2.68e-042752HP:0031475
HumanPhenoGeneralized non-motor (absence) seizure

KCNMA1 CHD2 DNM1

3.85e-0417653HP:0002121
HumanPhenoNon-motor seizure

KCNMA1 CHD2 DNM1

5.38e-0419753HP:0033259
HumanPhenoStatus epilepticus

KCNMA1 CHD2 DNM1

6.23e-0420753HP:0002133
HumanPhenoFalls

CHD2 DNM1

6.53e-044252HP:0002527
HumanPhenoGeneralized-onset motor seizure

KCNMA1 CHD2 DNM1

8.28e-0422853HP:0032677
HumanPhenoBilateral tonic-clonic seizure with generalized onset

KCNMA1 CHD2

1.00e-035252HP:0025190
HumanPhenoDialeptic seizure

KCNMA1 CHD2 DNM1

1.10e-0325153HP:0011146
HumanPhenoMyoclonic seizure

KCNMA1 CHD2 DNM1

1.25e-0326253HP:0032794
HumanPhenoAlmond-shaped palpebral fissure

CHD1 DNM1

1.29e-035952HP:0007874
HumanPhenoEEG with generalized epileptiform discharges

KCNMA1 CHD2 DNM1

1.36e-0327053HP:0011198
HumanPhenoGeneralized tonic seizure

CHD2 DNM1

1.52e-036452HP:0010818
HumanPhenoAbnormal shape of the palpebral fissure

CHD1 DNM1

1.56e-036552HP:0200005
HumanPhenoMultifocal epileptiform discharges

KCNMA1 CHD2

1.61e-036652HP:0010841
HumanPhenoInterictal epileptiform activity

KCNMA1 CHD2 DNM1

2.21e-0331953HP:0011182
HumanPhenoInterictal EEG abnormality

KCNMA1 CHD2 DNM1

2.34e-0332553HP:0025373
MousePhenoincreased apoptosis

RNF8 KCNMA1 PRAME SLC20A1 CHD1 TET1 STK40

3.82e-051008157MP:0006042
MousePhenoincreased cell death

RNF8 KCNMA1 PRAME SLC20A1 CHD1 TET1 STK40

4.10e-051019157MP:0012556
DomainDUF4208

CHD1 CHD2

2.34e-063172IPR025260
DomainDUF4208

CHD1 CHD2

2.34e-063172PF13907
DomainDUF4208

CHD1 CHD2

2.34e-063172SM01176
DomainChromodomain_CS

CHD1 CHD2

1.18e-0418172IPR023779
DomainChromo_domain

CHD1 CHD2

2.13e-0424172IPR023780
DomainChromo

CHD1 CHD2

2.50e-0426172PF00385
DomainCHROMO_2

CHD1 CHD2

2.91e-0428172PS50013
DomainCHROMO_1

CHD1 CHD2

2.91e-0428172PS00598
DomainSNF2_N

CHD1 CHD2

3.81e-0432172PF00176
DomainSNF2_N

CHD1 CHD2

3.81e-0432172IPR000330
DomainChromodomain-like

CHD1 CHD2

3.81e-0432172IPR016197
DomainCHROMO

CHD1 CHD2

4.05e-0433172SM00298
DomainChromo/shadow_dom

CHD1 CHD2

4.05e-0433172IPR000953
DomainDNA/RNA_helicase_DEAH_CS

CHD1 CHD2

4.56e-0435172IPR002464
DomainDEAH_ATP_HELICASE

CHD1 CHD2

5.38e-0438172PS00690
Domain-

ABCA6 CHD1 CHD2 DNM1

3.96e-037461743.40.50.300
DomainHelicase_C

CHD1 CHD2

4.18e-03107172PF00271
DomainHELICc

CHD1 CHD2

4.18e-03107172SM00490
DomainHelicase_C

CHD1 CHD2

4.26e-03108172IPR001650
DomainHELICASE_CTER

CHD1 CHD2

4.33e-03109172PS51194
DomainHELICASE_ATP_BIND_1

CHD1 CHD2

4.33e-03109172PS51192
DomainDEXDc

CHD1 CHD2

4.33e-03109172SM00487
DomainHelicase_ATP-bd

CHD1 CHD2

4.41e-03110172IPR014001
DomainP-loop_NTPase

ABCA6 CHD1 CHD2 DNM1

6.25e-03848174IPR027417
DomainZF_RING_1

RNF8 NFXL1

2.82e-02291172PS00518
DomainZF_RING_2

RNF8 NFXL1

2.95e-02298172PS50089
Pubmed

CHD1 and CHD2 are positive regulators of HIV-1 gene expression.

CHD1 CHD2

2.25e-07217225297984
Pubmed

CHD1 and SPOP synergistically protect prostate epithelial cells from DNA damage.

CHD1 CHD2

6.74e-07317233022763
Pubmed

Characterization of the CHD family of proteins.

CHD1 CHD2

1.35e-0641729326634
Pubmed

Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.

CHD2 TET1

6.17e-052417223920106
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

ZNF609 TET1

7.84e-052717223395962
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

NFXL1 PRAME CHD1 CHD2 ZNF609

2.15e-04120317529180619
Pubmed

Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.

KCNMA1 DNM1

2.94e-045217220114047
Pubmed

Analysis of the DNA sequence and duplication history of human chromosome 15.

CHD2 ZNF609

3.41e-045617216572171
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

NFXL1 SLC20A1 CHD1 ZNF609

3.74e-0473317434672954
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WDR76 CHRM3 PGBD2

3.47e-05170173a6fa0cab1fa829ec601fe48306b4c43c83425b04
ToppCell390C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

WDR76 CHRM3 PGBD2

3.47e-05170173b40255eee45eb18b5a297336d7f3845fd8f8aa3b
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNMA1 NFXL1 SORCS3

4.53e-0518617323b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KCNMA1 ABCA6 SORCS3

4.60e-0518717377886f99c229610abd28c4c370d2c7d1536c9782
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SLC20A1 CHD1 CHD2

4.68e-05188173ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 ABCA6 CHD1

4.98e-0519217311088878043a6ff95ba1970361256a82e434b80a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SLC20A1 CHD1 CHD2

4.98e-0519217347646d7e4990be85072987f92bf18d52f8da752e
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

ABCA6 SLC20A1 DNM1

5.13e-05194173d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 ABCA6 CHD1

5.21e-051951735c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

KCNMA1 ABCA6 DNM1

5.37e-0519717315b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

KCNMA1 ABCA6 DNM1

5.37e-05197173a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 CHRM3 DNM1

5.45e-051981736d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 CHRM3 DNM1

5.45e-051981738ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 CHRM3 DNM1

5.45e-05198173c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 CHRM3 DNM1

5.45e-051981734ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMA1 CHRM3 ZNF609

5.54e-0519917394b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMA1 CHRM3 TET1

5.62e-05200173682960e28542a3d6c119047cd0131941932cfdea
ToppCellBiopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ABCA6 TET1 DNM1

5.62e-05200173cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell(6)_Macrophage-(61)_LYVE1_Macrophage|(6)_Macrophage / shred on Cell_type and subtype

ABCA6 DNM1

6.25e-049817230a9a2abd0487e818628db589d31f630ca4d894b
ToppCell(09)_Ionocytes-(3)_72hpi|(09)_Ionocytes / shred by cell type and Timepoint

ZNF609 TET1

7.86e-04110172fce7d5a0617fc664b657f5bb9abb290e7cc234cb
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-5|TCGA-Stomach / Sample_Type by Project: Shred V9

PRAME DNM1

9.50e-04121172392700c5032b83d4d4e191fea9bcd170e4567b9d
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Metaplastic_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

SORCS3 CHRM3

9.81e-0412317251e49a64fbbf77e2ee21f45fd515d43282b11516
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Metaplastic_Carcinoma-4|TCGA-Breast / Sample_Type by Project: Shred V9

SORCS3 CHRM3

9.81e-0412317211802979943a9205f10facda322fc220d4bf7133
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

WDR76 KCNMA1

1.13e-03132172a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCellLPS-IL1RA+antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNMA1 DNM1

1.38e-03146172b76110b159acd27a2c8d6a9f98336608ace1ec12
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 CHRM3

1.43e-0314917210ffd0051fb027bbebc662ca602c80d89bbf99c6
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR76 TET1

1.53e-031541722d98bb7a784fc3215e0d4a1670d662e5df4716c3
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR76 TET1

1.53e-031541720dec222101530f1727184dbb7c03969d3884f111
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd|Liver / Manually curated celltypes from each tissue

CHRM3 DNM1

1.53e-03154172c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WDR76 CHRM3

1.55e-031551725d157478669b609e1f0f0a75afd0112571fc2c46
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WDR76 CHRM3

1.55e-03155172969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHD1 CHD2

1.55e-0315517277ae0b8d30bc3db4a73fd5340f99691a73d2684f
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STK40 DNM1

1.57e-03156172895927228c93cd090303984c5be6ebfb59ed6f3a
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

SLC20A1 CHD1

1.57e-031561721545169694f686d28648a68b552c2ae606599d66
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SORCS3 PGBD2

1.59e-031571722c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WDR76 ABCA6

1.63e-03159172999f30c7273ed77b34537621bcfcc7fc30121138
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WDR76 CHRM3

1.65e-03160172830e3ef8c9708d25872c3052a0b2682fa9372111
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNMA1 TET1

1.65e-03160172778faada072e3abfa76a9a06fd4885fb63de7902
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KCNMA1 SORCS3

1.67e-031611724bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KCNMA1 CHRM3

1.71e-031631721e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS|TCGA-Testes / Sample_Type by Project: Shred V9

PRAME PGBD2

1.71e-0316317267551fefe22bd5b8178fa248fed2a6c17b19fb0f
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Seminoma-_NOS-5|TCGA-Testes / Sample_Type by Project: Shred V9

PRAME PGBD2

1.71e-0316317280bc3732afd8501938753120b8403098c7c5e928
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD2 DNM1

1.73e-03164172d167c7a987b9b35d1e7725c803df4f9cd5380e47
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

KCNMA1 CHRM3

1.75e-031651725cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

KCNMA1 CHRM3

1.75e-03165172f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

ABCA6 SORCS3

1.75e-031651726ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA6 PRAME

1.77e-03166172d373f1092e85eeb317a7406032b259f11e6adbe0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA6 PRAME

1.77e-03166172f453a1d545d59003d98485ac31e85e6cf451817c
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KCNMA1 CHRM3

1.77e-031661726d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCellsevere-CD4+_T_naive|severe / disease stage, cell group and cell class

SORCS3 PGBD2

1.80e-0316717202a8215fca59c357c1cdaa5738849eacf98c0bcc
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF8 WDR76

1.82e-0316817208f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

WDR76 STK40

1.82e-03168172c3d2d573f21350a4a674faff30b06ff644d00ac3
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

KCNMA1 CHRM3

1.82e-03168172327b02f19f4a8607c033203824fdc60a1254331f
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA6 SORCS3

1.82e-0316817288c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell343B-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ABCA6 SLC20A1

1.84e-03169172632aa3ab39ec87bafcefec6cddf71129a054d3b0
ToppCellControl-T/NK_proliferative|World / Disease group and Cell class

RNF8 PGBD2

1.84e-03169172fca735cbb55fce4d32dc6632a39acea1d16b87ab
ToppCellLV-16._Neuronal|LV / Chamber and Cluster_Paper

ABCA6 SORCS3

1.84e-03169172a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SORCS3 CHRM3

1.86e-0317017214aa86a4f526ed6986afcb28c49225522055550c
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NFXL1 DNM1

1.88e-031711725e93c76ee60f9d0590ebb140812653a5e1369417
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

CHD1 CHD2

1.88e-031711722e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNMA1 CHRM3

1.88e-03171172fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

KCNMA1 CHRM3

1.88e-03171172e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

PRAME DNM1

1.90e-031721721b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 DNM1

1.90e-03172172e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KCNMA1 PRAME

1.92e-0317317209a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KCNMA1 PRAME

1.92e-03173172bfec038a6783f166240da4861e100643c6ea80a5
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 SLC20A1

1.92e-031731720c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

ABCA6 DNM1

1.95e-031741724c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCellRSV-Healthy-2|RSV / Virus stimulation, Condition and Cluster

TET1 MITD1

1.97e-031751720e97189585b7afaf3bd622c3ef10c86412393829
ToppCellRSV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

TET1 MITD1

1.97e-03175172c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KCNMA1 CHRM3

1.97e-03175172a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

WDR76 CHRM3

1.97e-03175172fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

WDR76 CHRM3

1.97e-0317517236c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Mast_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFXL1 CHD2

1.99e-031761720d203682c372411ba64e97a8eae6c4788e8b6ecf
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNMA1 CHRM3

1.99e-03176172a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCellDendritic_Cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ABCA6 DNM1

2.01e-03177172d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

ABCA6 DNM1

2.01e-03177172470f54fe2b21c7350ea471e02039461a3808f700
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KCNMA1 CHRM3

2.01e-0317717299500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNMA1 CHRM3

2.01e-03177172a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHRM3 DNM1

2.01e-031771724a697866ed542d3201714234cee03451adf1dcc9
ToppCelldroplet-Marrow-BM-30m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR76 SLC20A1

2.01e-03177172d1af0cb4b1fb03f04cff5add85e29be8fb8f4dcb
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KCNMA1 CHRM3

2.01e-03177172363e07b0f347f3716d530a28ead854b98e27d37c
ToppCelldroplet-Marrow-BM-30m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR76 SLC20A1

2.01e-03177172650095a17e1a39caea74a6e89646565b9332af5d
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 TET1

2.04e-0317817209475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 TET1

2.04e-0317817235de8f791b0e78a6caf52ff095f05e204a59e828
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 TET1

2.04e-03178172000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC20A1 CHD2

2.06e-031791726e965e424eebef50f0202cff75f458be395cfca1
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

KCNMA1 CHRM3

2.06e-03179172a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DNM1

2.08e-031801723d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 SORCS3

2.08e-031801729b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 SORCS3

2.08e-0318017208ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF609 DNM1

2.08e-03180172f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DNM1

2.08e-03180172d76349ecef7c5878bf215e946f032264161eb61b
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA6 SORCS3

2.10e-031811729e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFXL1 DNM1

2.10e-0318117257f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET1 DNM1

2.10e-031811727af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

PRAME DNM1

2.10e-0318117294680f8dbdf22d83801abc0819417751d363fb12
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFXL1 DNM1

2.10e-03181172d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD1 CHD2

2.13e-03182172eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KCNMA1 SORCS3

2.13e-03182172a8cc56f32efe180e8fb5d69dbe606a794b3db700
DiseaseLennox-Gastaut syndrome

CHD2 DNM1

4.13e-066162C0238111
DiseaseMetabolic Bone Disorder

KCNMA1 SLC20A1

2.50e-0514162C0005944
DiseaseOsteopenia

KCNMA1 SLC20A1

2.88e-0515162C0029453
DiseaseEpileptic encephalopathy

CHD2 DNM1

1.19e-0430162C0543888
Diseaseprostate cancer (implicated_via_orthology)

CHD1 CHD2

1.44e-0433162DOID:10283 (implicated_via_orthology)
Diseasesusceptibility to mumps measurement

KCNMA1 CHRM3

7.48e-0475162EFO_0008404
DiseaseEpilepsy, Cryptogenic

CHD2 DNM1

8.93e-0482162C0086237
DiseaseAwakening Epilepsy

CHD2 DNM1

8.93e-0482162C0751111
DiseaseAura

CHD2 DNM1

8.93e-0482162C0236018
DiseaseAutism Spectrum Disorders

CHD2 TET1

9.59e-0485162C1510586
DiseaseUterine leiomyoma

KCNMA1 PGBD2

1.10e-0391162HP_0000131
DiseaseNeurodevelopmental Disorders

CHD2 DNM1

1.15e-0393162C1535926
DiseaseEpilepsy

CHD2 DNM1

1.57e-03109162C0014544
Diseaselung disease severity measurement

KCNMA1 CHRM3

1.83e-03118162EFO_0007744
DiseasePapillary Renal Cell Carcinoma

KCNMA1 PRAME

2.15e-03128162C1306837
DiseaseRenal Cell Carcinoma

KCNMA1 PRAME

2.15e-03128162C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

KCNMA1 PRAME

2.15e-03128162C1266043
DiseaseChromophobe Renal Cell Carcinoma

KCNMA1 PRAME

2.15e-03128162C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

KCNMA1 PRAME

2.15e-03128162C1266044
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

KCNMA1 PRAME

2.86e-03148162C0279702
Diseaseautism spectrum disorder (implicated_via_orthology)

CHD1 CHD2

3.02e-03152162DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
CMELKCGKKRMRKDP

ABCA6

1216

Q8N139
KMLLLCQCDKKKRRK

CHRM3

556

P20309
ICKERMRPVKAALKQ

CHD1

1416

O14646
DPKRIKKCGCKRPKM

KCNMA1

686

Q12791
VKLRCPCKRIKKELQ

NFXL1

796

Q6ZNB6
QVKKIREPCLKCVDM

DNM1

416

Q05193
ICKERMRPVKKALKQ

CHD2

1471

O14647
CPRMKRKIEREIKCS

SLC20A1

251

Q8WUM9
KKMKKRICLVLDCLC

STK40

131

Q8N2I9
LRLCCKKLKIFAMPM

PRAME

206

P78395
MKRKIECPICRKDIK

RNF8

431

O76064
RFCEMLIKRPCKVKT

MITD1

136

Q8WV92
EPCVMGERKIFKKRK

SORCS3

711

Q9UPU3
PTLEKKKRKRCGVCE

TET1

581

Q8NFU7
RCPLKDPKELKKMKR

PGBD2

381

Q6P3X8
SLERKCMEKEKCKKP

ZNF609

626

O15014
CKKTKIKKTCRRIIP

WDR76

81

Q9H967