Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionalpha-tubulin binding

FNTA ARL8A INO80 ARL8B

1.49e-04521034GO:0043014
GeneOntologyMolecularFunctionmRNA m(6)A methyltransferase activity

METTL3 METTL16

1.57e-0441032GO:0001734
GeneOntologyCellularComponentGtr1-Gtr2 GTPase complex

RRAGC RRAGD

1.43e-0441032GO:1990131
HumanPhenoAbnormal cardiological findings

FLNC PSMD12 RYR1 RRAGC TNNI3K RRAGD GPC4 CORIN ATP1A3

2.04e-06178359HP:0003114
HumanPhenoAbnormal cardiac test

FLNC PSMD12 RYR1 RRAGC TNNI3K RRAGD GPC4 CORIN ATP1A3

2.14e-06179359HP:0500015
HumanPhenoAbnormal test result

FLNC PSMD12 RYR1 RRAGC TNNI3K RRAGD GPC4 CORIN ATP1A3

2.35e-06181359HP:0500014
HumanPhenoProlonged QT interval

FLNC PSMD12 RYR1 TNNI3K GPC4

2.83e-0554355HP:0001657
HumanPhenoAbnormality of jaw muscles

FLNC OBSCN RYR1 PI4KA

5.15e-0531354HP:0045037
HumanPhenoAbnormal QT interval

FLNC PSMD12 RYR1 TNNI3K GPC4

6.49e-0564355HP:0031547
DomainCyclin_Y

CCNY CCNYL1

2.90e-0521012IPR012399
DomainVWFC_2

VWF MUC19 THBS1 NELL2

5.16e-05381014PS50184
DomainVWC

VWF MUC19 THBS1 NELL2

5.16e-05381014SM00214
DomainVWF_dom

VWF MUC19 THBS1 NELL2

7.70e-05421014IPR001007
DomainVWC_out

VWF MUC19 NELL2

1.40e-04191013SM00215
DomainGtr1_RagA

RRAGC RRAGD

1.73e-0441012IPR006762
DomainGtr1_RagA

RRAGC RRAGD

1.73e-0441012PF04670
Domainzf-MYND

TDRD1 ANKMY2 SMYD3

1.90e-04211013PF01753
DomainZF_MYND_1

TDRD1 ANKMY2 SMYD3

2.19e-04221013PS01360
DomainZnf_MYND

TDRD1 ANKMY2 SMYD3

2.19e-04221013IPR002893
DomainZF_MYND_2

TDRD1 ANKMY2 SMYD3

2.19e-04221013PS50865
DomainKIND_dom

FRMPD2 PTPN13

2.86e-0451012IPR011019
DomainKIND

FRMPD2 PTPN13

2.86e-0451012SM00750
DomainKIND

FRMPD2 PTPN13

2.86e-0451012PS51377
DomainZinc_finger_PHD-type_CS

MTF2 KDM5A PHF3 KDM7A

4.23e-04651014IPR019786
DomainVWC

VWF THBS1 NELL2

4.56e-04281013PF00093
DomainPHD

MTF2 KDM5A PHF3 KDM7A

7.29e-04751014PF00628
Domain-

MID2 UBE4B MTF2 KDM5A RCHY1 PHF3 MID1 KDM7A RNF145

7.33e-0444910193.30.40.10
DomainZnf_RING/FYVE/PHD

MID2 UBE4B MTF2 KDM5A RCHY1 PHF3 MID1 KDM7A RNF145

8.56e-044591019IPR013083
DomainZnf_PHD-finger

MTF2 KDM5A PHF3 KDM7A

8.87e-04791014IPR019787
DomainVWFC_1

VWF THBS1 NELL2

9.63e-04361013PS01208
DomainMIF4G

CWC22 UPF2

1.27e-03101012SM00543
DomainMIF4G

CWC22 UPF2

1.27e-03101012PF02854
DomainMIF4G-like_typ-3

CWC22 UPF2

1.27e-03101012IPR003890
DomainPHD

MTF2 KDM5A PHF3 KDM7A

1.38e-03891014SM00249
DomainZnf_PHD

MTF2 KDM5A PHF3 KDM7A

1.50e-03911014IPR001965
DomainZF_PHD_2

MTF2 KDM5A PHF3 KDM7A

1.76e-03951014PS50016
DomainZF_PHD_1

MTF2 KDM5A PHF3 KDM7A

1.83e-03961014PS01359
DomainCOS

MID2 MID1

1.84e-03121012PS51262
DomainC8

VWF MUC19

1.84e-03121012PF08742
DomainTIL

VWF MUC19

1.84e-03121012PF01826
DomainCOS_domain

MID2 MID1

1.84e-03121012IPR017903
DomainUnchr_dom_Cys-rich

VWF MUC19

2.17e-03131012IPR014853
DomainC8

VWF MUC19

2.17e-03131012SM00832
DomainTIL_dom

VWF MUC19

2.53e-03141012IPR002919
DomainBbox_C

MID2 MID1

2.90e-03151012IPR003649
DomainBBC

MID2 MID1

2.90e-03151012SM00502
Domain-

CWC22 UPF2

2.90e-031510121.25.40.180
DomainSpectrin_alpha_SH3

PSTPIP1 TP53BP2

2.90e-03151012IPR013315
DomainMIF4-like

CWC22 UPF2

2.90e-03151012IPR016021
DomainVWF_type-D

VWF MUC19

3.31e-03161012IPR001846
DomainVWFD

VWF MUC19

3.31e-03161012PS51233
DomainVWD

VWF MUC19

3.31e-03161012SM00216
DomainVWD

VWF MUC19

3.31e-03161012PF00094
DomainCTCK_1

VWF MUC19

4.19e-03181012PS01185
DomainCation_ATPase_N

ATP13A2 ATP1A3

4.19e-03181012SM00831
DomainATPase_P-typ_cation-transptr_N

ATP13A2 ATP1A3

4.66e-03191012IPR004014
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ZHX3 MID2 RCHY1 PEG3 RRAGC LENG8 NELL2 SECISBP2 ATP1A3 TP53BP2 CDK6

1.99e-066081031116713569
Pubmed

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

ELAPOR2 METTL3 KRT81 KRT86 PEG3 CHD2 CWC22 PTPN13

2.18e-06284103829459677
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

FLNC ITCH VWF KDM5A PEG3 OBSCN CHD2 RYR1 UPF2 NUP133

2.34e-064971031023414517
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

PAG1 ITCH RASA3 PPP1R13B CCNY PTPN13 PI4KA MID1 EXOC4

4.72e-06421103936976175
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ITCH VWF UBE4B KDM5A PEG3 INTS8 PIAS1 BFSP1 DMAP1 THBS1 NELL2 PTPN13 HEATR6 SMYD3 EXOC4

5.84e-0612851031535914814
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

VIPR1 FUT10 ITCH MID2 UBE4B RASA3 FRMPD2 OBSCN CHD2 INTS8 CCNY TMCO4 ANKRD44 PTPN13 SMYD3 EXOC4

7.84e-0614891031628611215
Pubmed

Ocat, a paternally expressed gene closely linked and transcribed in the opposite direction to Peg3.

PEG3 USP29

8.69e-062103210903847
Pubmed

Relationship between thrombospondin gene variations, von Willebrand factor levels and the risk of coronary heart disease in an older population.

VWF THBS1

8.69e-062103221518247
Pubmed

Elongation factor ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation.

THBS1 ELL

8.69e-062103219447890
Pubmed

Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.

ARL8A ARL8B

8.69e-062103214871887
Pubmed

Parental and sexual conflicts over the Peg3 imprinted domain.

PEG3 USP29

8.69e-062103227901122
Pubmed

A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.

FLNC OBSCN

8.69e-062103229073160
Pubmed

Allele and dosage specificity of the Peg3 imprinted domain.

PEG3 USP29

8.69e-062103229734399
Pubmed

PSMD12 promotes the activation of the MEK-ERK pathway by upregulating KIF15 to promote the malignant progression of liver cancer.

PSMD12 KIF15

8.69e-062103236137220
Pubmed

Trans-allelic mutational effects at the Peg3 imprinted locus.

PEG3 USP29

8.69e-062103230335829
Pubmed

Thrombospondin-1 in von Willebrand factor function.

VWF THBS1

8.69e-062103218855616
Pubmed

Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53.

PPP1R13B TP53BP2

8.69e-062103215757645
Pubmed

Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome.

MID2 MID1

8.69e-062103226788540
Pubmed

Discovery of a novel, paternally expressed ubiquitin-specific processing protease gene through comparative analysis of an imprinted region of mouse chromosome 7 and human chromosome 19q13.4.

PEG3 USP29

8.69e-062103210958632
Pubmed

UBE4B interacts with the ITCH E3 ubiquitin ligase to induce Ku70 and c-FLIPL polyubiquitination and enhanced neuroblastoma apoptosis.

ITCH UBE4B

8.69e-062103237957138
Pubmed

Two evolutionarily conserved sequence elements for Peg3/Usp29 transcription.

PEG3 USP29

8.69e-062103219068137
Pubmed

Apoptosis stimulating protein of p53 (ASPP) 1 and ASPP2 m-RNA expression in oral cancer.

PPP1R13B TP53BP2

8.69e-062103232987288
Pubmed

DNA methylation analysis of the mammalian PEG3 imprinted domain.

PEG3 USP29

8.69e-062103219397955
Pubmed

[Promoter methylation of ASPP1 and ASPP2 genes in non-small cell lung cancers].

PPP1R13B TP53BP2

8.69e-062103222169642
Pubmed

Interstitial macrophage-derived thrombospondin-1 contributes to hypoxia-induced pulmonary hypertension.

THBS1 EPAS1

8.69e-062103231710666
Pubmed

An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.

ARL8A ARL8B

8.69e-062103216537643
Pubmed

Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice.

VWF THBS1

8.69e-062103214981081
Pubmed

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles.

ARL8A ARL8B

8.69e-062103230174114
Pubmed

Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma.

PPP1R13B TP53BP2

8.69e-062103220034025
Pubmed

ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells.

PPP1R13B TP53BP2

8.69e-062103223392125
Pubmed

A variable monilethrix phenotype associated with a novel mutation, Glu402Lys, in the helix termination motif of the type II hair keratin hHb1.

KRT81 KRT86

8.69e-06210329665406
Pubmed

Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in mice.

VWF THBS1

8.69e-062103225343959
Pubmed

ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.

PPP1R13B TP53BP2

8.69e-062103226595804
Pubmed

Imprinting control region (ICR) of the Peg3 domain.

PEG3 USP29

8.69e-062103222394678
Pubmed

A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix.

KRT81 KRT86

8.69e-06210329402962
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

PPP1R13B LENG8 PTPN13 NUP133 SECISBP2 TP53BP2 EXOC4

1.39e-05263103734702444
Pubmed

Association between variations in coagulation system genes and carotid plaque.

VWF THBS1

2.60e-053103222982001
Pubmed

ASPP: a new family of oncogenes and tumour suppressor genes.

PPP1R13B TP53BP2

2.60e-053103217211478
Pubmed

Analysis of imprinted murine Peg3 locus in transgenic mice.

PEG3 USP29

2.60e-053103215112106
Pubmed

Evaluating von Willebrand factor and ADAMTS13 levels in thalassemia major patients and assessing a possible association with Thrombospondin-1.

VWF THBS1

2.60e-053103237438087
Pubmed

ASPP--Apoptotic specific regulator of p53.

PPP1R13B TP53BP2

2.60e-053103216139958
Pubmed

Abnormal expression pattern of the ASPP family of proteins in human non-small cell lung cancer and regulatory functions on apoptosis through p53 by iASPP.

PPP1R13B TP53BP2

2.60e-053103222552744
Pubmed

MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.

MID2 MID1

2.60e-053103211806752
Pubmed

Sequence data and chromosomal localization of human type I and type II hair keratin genes.

KRT81 KRT86

2.60e-05310327556444
Pubmed

Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis.

CCNY CCNYL1

2.60e-053103222184064
Pubmed

Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro.

VWF THBS1

2.60e-053103220705333
Pubmed

Structure and site of expression of a murine type II hair keratin.

KRT81 KRT86

2.60e-05310321372089
Pubmed

Imprinted methylation profiles for proximal mouse chromosomes 11 and 7 as revealed by methylation-sensitive representational difference analysis.

PEG3 USP29

2.60e-053103214724735
Pubmed

P-selectin can promote thrombus propagation independently of both von Willebrand factor and thrombospondin-1 in mice.

VWF THBS1

2.60e-053103227943541
Pubmed

Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins.

KRT81 KRT86

2.60e-05310321712823
Pubmed

Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability.

PPP1R13B TP53BP2

2.60e-053103223644657
Pubmed

CCNYL1, but Not CCNY, Cooperates with CDK16 to Regulate Spermatogenesis in Mouse.

CCNY CCNYL1

2.60e-053103226305884
Pubmed

Targeting key RNA methylation enzymes to improve the outcome of colorectal cancer chemotherapy (Review).

METTL3 METTL16

2.60e-053103238131226
Pubmed

Inversion of the imprinting control region of the Peg3 domain.

PEG3 USP29

2.60e-053103228719641
Pubmed

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

RRAGC RRAGD

2.60e-053103224095279
Pubmed

Pirh2, an E3 ligase, regulates the AIP4-p73 regulatory pathway by modulating AIP4 expression and ubiquitination.

ITCH RCHY1

2.60e-053103233569599
Pubmed

Novel KRT83 and KRT86 mutations associated with monilethrix.

KRT81 KRT86

2.60e-053103225557232
Pubmed

ASPP1 and ASPP2 are new transcriptional targets of E2F.

PPP1R13B TP53BP2

2.60e-053103215731768
Pubmed

The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly.

PPP1R13B TP53BP2

2.60e-053103225660448
Pubmed

The E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stability.

ITCH TP53BP2

2.60e-053103225436413
Pubmed

A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior.

PEG3 USP29

2.60e-053103227187722
Pubmed

Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis.

PEG3 THBS1

2.60e-053103228174297
Pubmed

Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study.

PPP1R13B TP53BP2

2.60e-053103228103919
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

FLNC METTL3 OBSCN IFT46 RYR1 THBS1

4.40e-05214103622199357
Pubmed

Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy.

VWF CORIN

5.19e-054103222437503
Pubmed

Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.

ARL8A ARL8B

5.19e-054103215331635
Pubmed

MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation.

MID2 MID1

5.19e-054103211685209
Pubmed

METTL3 aggravates cell damage induced by Streptococcus pneumoniae via the NEAT1/CTCF/MUC19 axis.

METTL3 MUC19

5.19e-054103238757482
Pubmed

Two cellular proteins that bind to wild-type but not mutant p53.

ELL TP53BP2

5.19e-05410328016121
Pubmed

Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.

KRT81 KRT86

5.19e-05410329457912
Pubmed

ASPP1 and ASPP2: common activators of p53 family members.

PPP1R13B TP53BP2

5.19e-054103214729977
Pubmed

VHL-HIF-2α axis-induced SMYD3 upregulation drives renal cell carcinoma progression via direct trans-activation of EGFR.

EPAS1 SMYD3

5.19e-054103232291411
Pubmed

ASPP proteins specifically stimulate the apoptotic function of p53.

PPP1R13B TP53BP2

5.19e-054103211684014
Pubmed

Keratins of the human hair follicle.

KRT81 KRT86

5.19e-054103215797458
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FLNC MID2 KDM5A LSG1 INO80 PTPN13 UPF2 PHF3 SECISBP2 EXOC4

5.95e-057241031036232890
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLNC VWF MTF2 KRT81 PPP1R13B PIAS1 SECISBP2 EPAS1 TP53BP2

6.77e-05591103915231748
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZHX3 MTF2 KDM5A CHD2 INO80 PIAS1 DMAP1 FSIP2 PHF3

8.39e-05608103936089195
Pubmed

ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo.

PPP1R13B TP53BP2

8.64e-055103223365256
Pubmed

TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.

THBS1 EPAS1

8.64e-055103228555642
Pubmed

Mdm2 and mdmX prevent ASPP1 and ASPP2 from stimulating p53 without targeting p53 for degradation.

PPP1R13B TP53BP2

8.64e-055103215782125
Pubmed

Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor.

VWF THBS1

8.64e-055103215799029
Pubmed

The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53.

PPP1R13B TP53BP2

8.64e-055103221513714
Pubmed

ASPP2 suppresses invasion and TGF-β1-induced epithelial-mesenchymal transition by inhibiting Smad7 degradation mediated by E3 ubiquitin ligase ITCH in gastric cancer.

ITCH TP53BP2

8.64e-055103228400336
Pubmed

Increases of iASPP-Keap1 interaction mediated by syringin enhance synaptic plasticity and rescue cognitive impairments via stabilizing Nrf2 in Alzheimer's models.

PPP1R13B TP53BP2

8.64e-055103232828017
Pubmed

SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.

RRAGC RRAGD

8.64e-055103222575674
Pubmed

Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells.

CCNY CCNYL1

8.64e-055103227203244
Pubmed

A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.

RRAGC RRAGD

8.64e-055103232612235
Pubmed

Imprinting and evolution of two Kruppel-type zinc-finger genes, ZIM3 and ZNF264, located in the PEG3/USP29 imprinted domain.

PEG3 USP29

8.64e-055103211543637
Pubmed

Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains.

PPP1R13B TP53BP2

8.64e-055103211278422
Pubmed

A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.

RRAGC RRAGD

1.29e-046103214660641
Pubmed

USP37 promotes deubiquitination of HIF2α in kidney cancer.

USP29 EPAS1

1.29e-046103232461361
Pubmed

Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins.

PPP1R13B TP53BP2

1.29e-046103223088536
Pubmed

Regulation of Itch and Nedd4 E3 Ligase Activity and Degradation by LRAD3.

ITCH ATP1A3

1.29e-046103226854353
Pubmed

Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.

RRAGC RRAGD

1.29e-046103211073942
Pubmed

Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.

RRAGC RRAGD

1.29e-046103224529380
Pubmed

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.

MID2 MID1

1.29e-046103216434393
Pubmed

Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif.

PPP1R13B TP53BP2

1.29e-046103221998301
Pubmed

Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.

RRAGC RRAGD

1.29e-046103224081491
Pubmed

HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.

THBS1 EPAS1

1.29e-046103226503986
Pubmed

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.

RRAGC RRAGD

1.29e-046103218497260
Cytoband12q12

ASIC1 MUC19 NELL2

1.66e-0447103312q12
GeneFamilyPHD finger proteins

MTF2 KDM5A PHF3 KDM7A

5.60e-049076488
CoexpressionGSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP

VIPR1 PAG1 RPL32 RASA3 VNN2 CD48 KDM7A

1.11e-051921037M6592
CoexpressionGSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_DN

VIPR1 MTF2 CPEB3 PSMD12 INTS8 PHF3 NUP133

1.40e-051991037M4310
CoexpressionRIGGI_EWING_SARCOMA_PROGENITOR_UP

PAG1 PEG3 PSTPIP1 NELL2 PTPN13 RRAGD CYP4F22 CORIN CCDC171

5.77e-054371039M15981
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

ZHX3 MTF2 KDM5A UPF2 PHF3 MID1 ANKMY2 TP53BP2 FILIP1L

9.42e-054661039M13522
CoexpressionGSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_UP

PAG1 RPL32 RASA3 NELL2 CD48 KDM7A

1.20e-041941036M6595
CoexpressionGSE360_L_DONOVANI_VS_L_MAJOR_DC_DN

METTL3 VWF CHD2 LIG4 PTPN13 ATP1A3

1.27e-041961036M5194
CoexpressionGSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP

ASTE1 CCNY POSTN ARL8B SECISBP2 PRMT9

1.30e-041971036M4237
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ZHX3 ITCH MTF2 KDM5A PTPN13 UPF2 PHF3 MID1 NUP133 ANKMY2 TP53BP2 FILIP1L

1.37e-0485610312M4500
CoexpressionGSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_UP

RPL32 ITCH CWC22 CCNYL1 MID1 PRRG3

1.38e-041991036M6581
CoexpressionGSE3982_EOSINOPHIL_VS_BASOPHIL_DN

METTL3 UBE4B INTS8 KDM7A EPAS1 SMYD3

1.38e-041991036M5414
CoexpressionGSE4142_GC_BCELL_VS_MEMORY_BCELL_UP

ITCH PSTPIP1 UPF2 PI4KA RNF145 FILIP1L

1.42e-042001036M6397
CoexpressionGSE40685_NAIVE_CD4_TCELL_VS_TREG_DN

RYR1 DMAP1 PTPN13 ANKMY2 CCDC171 SMYD3

1.42e-042001036M9303
CoexpressionGSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP

RASA3 ATP13A2 ANKRD44 THBS1 KDM7A EPAS1

1.42e-042001036M9737
CoexpressionGSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP

ITCH MID2 RASA3 ATP13A2 ANKRD44 ANKMY2

1.42e-042001036M7234
CoexpressionGSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP

PAG1 RASA3 PSTPIP1 ATP13A2 CD48 RNF145

1.42e-042001036M7270
CoexpressionGSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP

VWF CPEB3 RRAGC RRAGD CD48 PRMT9

1.42e-042001036M8630
CoexpressionGSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP

VIPR1 PAG1 HEATR6 PHF3 EPAS1 FILIP1L

1.42e-042001036M9278
CoexpressionGSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN

RASA3 PPP1R13B PSTPIP1 CWC22 PRMT9 FILIP1L

1.42e-042001036M8781
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIPR1 PSTPIP1 PTPN13 KIF15 ACSBG1 EXOC4

2.63e-061681036a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2 CD48

5.33e-061901036ba61f04fd38efae01f721ba616252d1372ff1002
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2 CD48

5.33e-06190103607ea0578ca0561077557203ae660530f53fc4067
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2 CD48

5.33e-0619010365a37568000dfc33fcbb59b578c1963fb7cf872ec
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2 CD48

5.33e-0619010365b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2 CD48

5.50e-06191103696a7179a845d3daa046ed71fa45c51255f130a7f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2 CD48

5.66e-061921036b498618505bb1b7ff9574d06875dd272c11bac39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2 CD48

5.83e-06193103612f1333f11e6c262954ad7912d8fd2962ab06d25
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAG1 OBSCN THBS1 ATP1A3 FILIP1L

3.53e-051601035237430af14830b38e58da8a4224036e5c6b71c5b
ToppCellnormal_Lung-T/NK_cells-Naive_CD8+_T|normal_Lung / Location, Cell class and cell subclass

MMS22L RPL32 PSTPIP1 ANKRD44 CD48

3.53e-05160103597a4c69824e8708fbb12c468be1828d24a111db3
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|(1)_Control_(PBS) / Stress and Cell class

PEG3 PSTPIP1 POSTN THBS1 CD48

3.53e-0516010358450466fc2465c56798df2b520edd23c2c2e941c
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

PAG1 CHD2 ANKRD44 NELL2 EXOC4

3.75e-051621035b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF492 KRT81 KRT86 PSTPIP1 ATP1A3

3.86e-051631035e6213900f56257fe38ac7852351bea0340294be0
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF492 KRT81 KRT86 PSTPIP1 ATP1A3

3.86e-051631035ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF492 KRT81 KRT86 PSTPIP1 ATP1A3

3.86e-051631035ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Teffector/EM_CD4|GI_small-bowel / Manually curated celltypes from each tissue

VIPR1 RPL32 RASA3 NELL2 ETNK2

4.09e-051651035ecaeb90a6bc27524ef6f2eefa72aec7315dbde3b
ToppCelldroplet-Lung-nan-18m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITCH RASA3 THBS1 KDM7A ATP1A3

4.09e-051651035e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCelldroplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITCH RASA3 THBS1 KDM7A ATP1A3

4.09e-0516510350fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCellMonocytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

PSTPIP1 ANKRD44 CD48 CYP4F22 CD180

4.71e-0517010354e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 PSTPIP1 ANKRD44 NELL2 CD48

5.26e-05174103547e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 PSTPIP1 ANKRD44 NELL2 CD48

5.26e-051741035a92c745d20633909db0f08effa13fc738fda79a6
ToppCellASK452-Endothelial-Endothelium|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq

VWF POSTN EPAS1

5.51e-05321033fd0777da59e8ac3e0f766071977cb169d058e5ae
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RASA3 PSTPIP1 VNN2 CD48 ATP1A3

5.71e-051771035bb496fbec7cacc52847abe2b2714249c47879763
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 PSTPIP1 ANKRD44 NELL2 CD48

6.02e-051791035874a9afa91774221c9c1775aa4968ba0aea7b554
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAG1 POSTN GPC4 FILIP1L CDK6

6.02e-05179103556db12467b445f2b8ef92af50779eeab10413eb2
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

RCHY1 RRAGC HEATR6 RRAGD ARL8B

6.34e-0518110359d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAG1 POSTN KCNT2 GPC4 FILIP1L

6.86e-051841035689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAG1 POSTN KCNT2 GPC4 FILIP1L

6.86e-051841035327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

PAG1 MMS22L ANKRD44 EXOC4 CDK6

7.04e-051851035a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

PAG1 MMS22L ANKRD44 EXOC4 CDK6

7.22e-0518610358571956890fc9894d766ba294a28e376b4aba428
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAG1 POSTN GPC4 FILIP1L CDK6

7.59e-051881035a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASA3 PSTPIP1 ANKRD44 NELL2 CD48

7.78e-051891035b87d586a9570fa54f3e0c6bd4731c5badcaedae6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASA3 PSTPIP1 ANKRD44 NELL2 CD48

7.78e-051891035823d6debd09e440ddf36c54af24a5f20e222a21e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RASA3 PSTPIP1 ANKRD44 NELL2 CD48

7.78e-05189103547c2b419b081d5bf75da5e3d9a0e05a70362dfe7
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAG1 POSTN GPC4 FILIP1L CDK6

7.78e-051891035ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

VIPR1 VWF ANKRD44 POSTN EPAS1

7.98e-0519010357f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAG1 POSTN GPC4 FILIP1L CDK6

7.98e-051901035951e067d14412db67dc3babcdf61e41717d7b429
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

8.18e-051911035d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

8.18e-051911035b42c54308abe1241cc38ddce96b9d38d07983891
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

8.18e-0519110355a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

PAG1 MMS22L ANKRD44 EXOC4 CDK6

8.18e-0519110359454f642c3621370fa23640b631301346b300950
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ELAPOR2 PPP1R13B PTPN13 RNF145 SMYD3

8.18e-051911035e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

8.18e-0519110359aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

VIPR1 PAG1 RPL32 NELL2 PTPN13

8.18e-05191103525dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

VWF POSTN PTPN13 KCNT2 EPAS1

8.38e-05192103560b1312e84f6d6448365a952469c506c00b5fe93
ToppCellT_cells-Central_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

VIPR1 PAG1 RPL32 NELL2 PTPN13

8.59e-051931035725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCell343B-Myeloid-Monocyte-CD14+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RPL32 PSTPIP1 THBS1 VNN2 CD48

8.59e-05193103524c06b0461894fe9f68bf26507d7a708468237c2
ToppCell10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PAG1 KRT81 KRT86 CORIN EPAS1

8.80e-0519410355da8873cddff582e5693b32fd3aaebc102f65fc0
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN THBS1 GPC4 CORIN FILIP1L

8.80e-051941035c992e3357f4bf3069f8d697803e5785e49a2ef0a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

8.80e-0519410354dfc890bacf133cfb6ec7c8b73f084f2491cf78e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

8.80e-051941035633fe72cc8a489abde12428e326478409ca03263
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

8.80e-05194103587a86df0b542f287b0b20f4a4b1a37002271671d
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIPR1 VWF OBSCN POSTN EPAS1

8.80e-05194103540842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCellASK440-Endothelial-Endothelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

VIPR1 VWF MUC19 POSTN EPAS1

9.01e-051951035304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAG1 PSTPIP1 RYR1 ANKRD44 CD48

9.01e-051951035ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCellASK428-Endothelial-Endothelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

VWF POSTN THBS1 EPAS1 FILIP1L

9.23e-051961035b1a81eddb91fb462360692b7b0a3ba4a947eac40
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

PSTPIP1 THBS1 VNN2 CD48 PRMT9

9.23e-051961035376c5a459a484205fbb0db34936e4a6146d1f622
ToppCellcontrol-Lymphocytic-CD4_T_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

VIPR1 PAG1 RPL32 NELL2 CD48

9.23e-0519610354f8670257ea6fdf58cb102b4c7dc9ba39bb317ef
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POSTN THBS1 GPC4 TSHZ1 FILIP1L

9.23e-0519610359d7b631f24a19a7dc7a28f28525d4019fc8fcf8a
ToppCellIPF-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

PAG1 NELL2 PTPN13 N4BP2 TP53BP2

9.23e-0519610356e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Teffector/EM_CD4|bone_marrow / Manually curated celltypes from each tissue

PAG1 RPL32 NELL2 PTPN13 CD48

9.46e-05197103573a13d4dc76476f3a38b09b776779c5b7d67171f
ToppCellCOVID-19-kidney-T-cells-1|kidney / Disease (COVID-19 only), tissue and cell type

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

9.46e-0519710359bb7faf4ef63cca4d06c60e6c05a9616fdb6b98e
ToppCelldistal-Hematologic-Classical_Monocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPL32 PSTPIP1 THBS1 VNN2 CD48

9.46e-0519710359f4b0857012cd503e668bac115010216a946f73c
ToppCellMild-Lymphoid-NK-NK|Mild / Condition, Lineage, Cell class and cell subclass

RPL32 KRT81 KRT86 CD48 CDK6

9.69e-0519810354999cc14642df704819be55594a07eab9c6527aa
ToppCellB_cells-Activate_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

RASA3 ANKRD44 VNN2 CD48 CD180

9.69e-051981035a663082d7fbd6db11d3d3024bbb8ba00183e19f8
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POSTN THBS1 GPC4 TSHZ1 FILIP1L

9.69e-0519810350993d6895c0e4f360998ce35abea4ec3dd13e048
ToppCellASK428-Endothelial|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

VWF POSTN THBS1 EPAS1 FILIP1L

9.69e-051981035d69d0ff115298596173a4278897a65007a71f5df
ToppCellTracheal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT81 KRT86 PSTPIP1 ANKRD44 CD48

9.69e-05198103590318a238fdf129ef719843edd05c063ef75e9cc
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL|Int-URO / Disease, condition lineage and cell class

FUT10 FNTA PPP1R13B BFSP1 SMYD3

9.69e-051981035717735d755745439f97ba1b71785c73945dfa9c5
ToppCelldistal-3-Hematologic-Classical_Monocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPL32 PSTPIP1 THBS1 VNN2 CD48

9.92e-051991035cd7c304076d14315dc24cf56eb5e06b9426710be
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PAG1 RASA3 PSTPIP1 ANKRD44 NELL2

9.92e-0519910356150b272313d3fbf5ddcb3a8d51862d368220fe2
ToppCelldistal-Hematologic-Classical_Monocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPL32 PSTPIP1 THBS1 VNN2 CD48

9.92e-051991035bd8519da7a90f0b90626b86c6be0d62248a0a24a
ToppCelldistal-Hematologic-Classical_Monocyte-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPL32 PSTPIP1 THBS1 VNN2 CD48

9.92e-051991035cd691f1c2493516d7553cc9a005f6e3b442bdbd5
ToppCellMild-Lymphoid-NK|Mild / Condition, Lineage, Cell class and cell subclass

RPL32 KRT81 KRT86 CD48 CDK6

9.92e-051991035ae8b16e5463c3c41807fef187ee9f501df07e452
ToppCell10x5'-Lung-Lymphocytic_T_CD4-Teffector/EM_CD4|Lung / Manually curated celltypes from each tissue

VIPR1 RPL32 NELL2 PTPN13 CD48

9.92e-05199103554b6a43e23826d507b8f1db578e589711d49bbfd
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PAG1 POSTN KCNT2 GPC4 FILIP1L

1.02e-042001035d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PAG1 POSTN KCNT2 GPC4 FILIP1L

1.02e-042001035cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellTracheal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VIPR1 RPL32 VWF CORIN EPAS1

1.02e-042001035fe493b0454a20498e9ada482bf55de64519f6c35
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PAG1 POSTN KCNT2 GPC4 FILIP1L

1.02e-042001035786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

PAG1 POSTN KCNT2 GPC4 FILIP1L

1.02e-042001035cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

PAG1 POSTN KCNT2 GPC4 FILIP1L

1.02e-04200103569edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

POSTN KCNT2 GPC4 TSHZ1 FILIP1L

1.02e-0420010358bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCelldistal-1-Hematologic-Classical_Monocyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RPL32 PSTPIP1 CCNY VNN2 CD48

1.02e-0420010353e672dd51ed72e8109691e5ca2fa2801b0539958
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

PAG1 POSTN KCNT2 GPC4 FILIP1L

1.02e-042001035bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KRT86 NLRP14 PRMT9 CYP4F22

2.36e-0413010341720f16ac06951c3f57b6c3b0944670a571203d1
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-3|TCGA-Mesothelium / Sample_Type by Project: Shred V9

PTPN13 KCNT2 MID1 FILIP1L

2.88e-041371034a1e34ebbeda3d5a4f14917282d44fcb4dcbf3133
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC TDRD1 KIF15 CCDC171

2.96e-041381034c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD8-gdT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

KRT86 PSTPIP1 CD48 CYP4F22

2.96e-041381034769be787e24532d5e023f99f82c7272bddac40c3
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Cbln2-Htr2c_(Deep_layer_subiculum)|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT81 KRT86 GNGT1

3.12e-0457103335494ca30bdafb4c175d74f0b4892098411784b0
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC TDRD1 KIF15 CCDC171

3.30e-04142103467d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCellPBMC-Mild-cDC_7|Mild / Compartment, Disease Groups and Clusters

VIPR1 FRMPD2 IFT46 NUP133

3.30e-04142103458f66f35646f281e64d634e6c26adbd1d4e6c830
ToppCellCOVID-19_Severe-MAIT|World / disease group, cell group and cell class

MID2 USP29 PTPN13 ETNK2

3.57e-0414510348d63f97812f63329ef9c940b291dc5a1c4d90690
ToppCellE16.5-samps-Mesenchymal-Pericyte|E16.5-samps / Age Group, Lineage, Cell class and subclass

PPP1R13B POSTN CCNYL1 EPAS1

3.86e-041481034e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCellE16.5-samps-Mesenchymal-Pericyte-pericyte_A|E16.5-samps / Age Group, Lineage, Cell class and subclass

PPP1R13B POSTN CCNYL1 EPAS1

3.86e-041481034c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCellCOVID-19_Severe-MAIT|COVID-19_Severe / disease group, cell group and cell class

MID2 USP29 PTPN13 ETNK2

4.06e-041501034923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT86 TDRD1 FSIP2

4.39e-046410332edc3ae3e334bb04a411778e3b102b3a84a97824
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12-Inhibitory_Gad1Gad2Slc17a8_Htr3a.Ktcd12_(Interneuron,__GABA/Glutamate_co-releasing?_(candidate_CGE-derived_9))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT86 TDRD1 FSIP2

4.39e-04641033b8aac6e83c2e5b09b55ea22ddb29940099f186e1
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Kctd12-Inhibitory_Gad1Gad2Slc17a8_Htr3a.Ktcd12_(Interneuron,__GABA/Glutamate_co-releasing?_(candidate_CGE-derived_9))|Hippocampus / BrainAtlas - Mouse McCarroll V32

KRT86 TDRD1 FSIP2

4.39e-046410333e3eed30abcecd3fc8d30489dca05222ac353180
ToppCellIonocyte|World / shred by cell class for nasal brushing

POSTN THBS1 CORIN GNGT1

4.49e-0415410346b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|390C / Donor, Lineage, Cell class and subclass (all cells)

KRT86 LENG8 UPF2 PRMT9

4.60e-04155103498d8432739965dd1ab77c899cb6321f7f05eaa46
Diseasehair disease (is_implicated_in)

KRT81 KRT86

1.11e-052992DOID:421 (is_implicated_in)
DiseaseBeaded hair

KRT81 KRT86

3.34e-053992cv:C0546966
DiseaseMONILETHRIX

KRT81 KRT86

3.34e-053992158000
Diseasemonilethrix (is_implicated_in)

KRT81 KRT86

3.34e-053992DOID:0050472 (is_implicated_in)
DiseaseMonilethrix

KRT81 KRT86

6.66e-054992C0546966
Diseasefollicular lymphoma (implicated_via_orthology)

RRAGC RRAGD

1.11e-045992DOID:0050873 (implicated_via_orthology)
DiseaseOpitz GBBB syndrome (implicated_via_orthology)

MID2 MID1

1.66e-046992DOID:0080697 (implicated_via_orthology)
Diseaserectum cancer, overall survival

CWC22 PIAS1

1.14e-0315992EFO_0000638, EFO_1000657
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

PAG1 LIG4 CDK6

1.14e-0361993C1961102
DiseaseAutosome Abnormalities

EPAS1 CDK6

1.30e-0316992C0004403
DiseaseChromosome Aberrations

EPAS1 CDK6

1.30e-0316992C0008625
Diseasepancreatic ductal carcinoma (is_implicated_in)

THBS1 CDK6

1.30e-0316992DOID:3587 (is_implicated_in)
DiseaseSjogren's syndrome (implicated_via_orthology)

MUC19 THBS1

1.47e-0317992DOID:12894 (implicated_via_orthology)
DiseaseS-6-hydroxywarfarin measurement

CWC22 PIAS1 CCNY ANKRD44 ARL8B GNGT1

1.53e-03368996EFO_0803326
Diseasereaction time measurement

MMS22L RCHY1 MUC19 ANKRD44 N4BP2 TSHZ1 CCDC171 EPAS1

1.69e-03658998EFO_0008393
Diseasemyocardial infarction (biomarker_via_orthology)

VWF POSTN THBS1 EPAS1

2.10e-03160994DOID:5844 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QEKLCMLTAELLEYC

TDRD1

966

Q9BXT4
CIMCVNYVLSEIEKN

EPAS1

336

Q99814
DGTCTLQDCMYKDVQ

ELL

256

P55199
CELSKTMYELACDVV

PRMT9

206

Q6P2P2
YNEKSCSELQEELVM

CCDC171

391

Q6TFL3
MEKDGLCRADQQYEC

CDK6

1

Q00534
DYCQILKDITVEDMN

CCNY

236

Q8ND76
QMCIEKEANKTYNCE

CD180

26

Q99467
DYCQILKDITVEDMN

CCNYL1

256

Q8N7R7
AADKCEEMEEGYIQC

PPP1R13B

991

Q96KQ4
DKCEEMEEGYTQCSQ

TP53BP2

1031

Q13625
ENVKELLCCSMEEYQ

ASTE1

286

Q2TB18
LLCCSMEEYQQSQVK

ASTE1

291

Q2TB18
EYSEAPNEMVICDKC

MTF2

111

Q9Y483
SKMRDCYCTVNLDQE

RASA3

31

Q14644
DCMEEKNQAVCHDYD

QSOX2

121

Q6ZRP7
LKVKTEEMQCQVCYD

INTS8

241

Q75QN2
VENELSDKIEILMYC

INO80

751

Q9ULG1
KMNLSAIQDREICCY

ARL8B

146

Q9NVJ2
KMNLSAIQDREICCY

ARL8A

146

Q96BM9
YCDFDILVQMCEQTD

NUP133

866

Q8WUM0
NQLSMQCVKDDELYE

PSTPIP1

236

O43586
YDVNRFMIECDICKD

KDM7A

46

Q6ZMT4
EEVQSALYNKEMECL

KIF15

1271

Q9NS87
CEDLECYVKEMDANK

LSG1

191

Q9H089
CVLYECKDQTMKLVE

NELL2

356

Q99435
CCSQEMEEKYSLQSK

GPC4

66

O75487
MVKTCCCDKQDQELY

MMS22L

461

Q6ZRQ5
QDMKEYVERCFTACE

LENG8

291

Q96PV6
MDCIIAEIKAQYDDI

KRT86

271

O43790
NMILDCCAQQRTYEK

CWC22

491

Q9HCG8
CECLQVDYMSDLLEN

FSIP2

3811

Q5CZC0
LVACYVEEDMQDCVL

ETNK2

96

Q9NVF9
MICIDEYCQTRDKTS

MUC19

671

Q7Z5P9
INCEDMEDGTCKVTY

FLNC

2086

Q14315
TQAYLMELGEVICKC

HEATR6

706

Q6AI08
GMCQALEIQDKEYLC

PI4KA

166

P42356
KEESEIIYDFCMCNP

METTL16

171

Q86W50
MLVSKCCEEVRDYVE

GNGT1

31

P63211
LQMALSEEDCCFKDN

ANKRD44

756

Q8N8A2
CEEEFKYAMLALNCI

KCNT2

436

Q6UVM3
VAKMVQQCCTYVEEI

PSMD12

101

O00232
EYLEMKNQVCSKCGE

ELAPOR2

111

A8MWY0
EMAENEDYICINCAK

KDM5A

1646

P29375
YLVECKNQECEEAFM

PEG3

531

Q9GZU2
QVQEFCDYGTKEECM

METTL3

271

Q86U44
CDTDDDVAMCFIKNQ

OBSCN

5761

Q5VST9
VKENNIEECDLEMYF

ITCH

691

Q96J02
NMVCVKLQEYKDTCT

EXOC4

606

Q96A65
ELVCELQKLQYCVGM

ATP13A2

861

Q9NQ11
EIDCSLAEYIDMICA

IFT46

231

Q9NQC8
IKRMVEDSDLQTCYC

LIG4

351

P49917
VKPYVLDDQMCDECQ

CPEB3

626

Q8NE35
CVSAMQEYEEQLKEN

CHD2

1181

O14647
ELKQACANCEYELQM

DMAP1

376

Q9NPF5
MEKSDEFICLLEQEC

FILIP1L

186

Q4L180
EKDVRQNCYSVCDIM

FRMPD2

1276

Q68DX3
DNYIDAFECMVCTKV

FUT10

381

Q6P4F1
KYENECECQLLLKEM

BFSP1

126

Q12934
YDCCANVIMVDTQKQ

ACSBG1

201

Q96GR2
EAALNKCYRVMDLIC

ANKMY2

191

Q8IV38
YMDEKNCSFCQDDEL

CORIN

646

Q9Y5Q5
MSVEEVCRKYNTDCV

ATP1A3

36

P13637
IEDMDDNCYLKLSCV

CD48

141

P09326
QTYELCCDMIDVVID

RRAGD

281

Q9NQL2
KLQMCHLLEYFCDQE

RYR1

1936

P21817
NCQEKMSDYISAIIE

CYP4F22

221

Q6NT55
ATKMNGCEEYCEEKV

PTPN13

2116

Q12923
QDQEVKDYVICCMIN

UPF2

801

Q9HAU5
EVLLMCNKSYCAEIA

RPL32

86

P62910
SYELCCDMIDVVIDV

RRAGC

281

Q9HB90
YFCLQEMAQEKDCQG

TMCO4

411

Q5TGY1
VDIYEDMLENQCDNK

FNTA

316

P49354
DAKLVMEYLAICDEC

GARS1

511

P41250
DYCSQMLSKEVDACV

SECISBP2

631

Q96T21
LFMEILKYCTDCDEI

PIAS1

391

O75925
SQENMVEDCLYETVK

PAG1

171

Q9NWQ8
YQLKVLDCAMDACIN

SMYD3

326

Q9H7B4
DFLVEKDQEYCVCEM

ASIC1

351

P78348
ACEIQKCLQANSYME

CMC4

11

P56277
QDMYQCLVEGCTEKF

ZNF511

141

Q8NB15
CCHLSYRMLQKEENE

VNN2

366

O95498
ECDYVQMIEVQHKQC

VIPR1

36

P32241
QLYIDCEKMENAELD

THBS1

166

P07996
LECTKTCQNYDLECM

VWF

786

P04275
EQKENCLDCYMDPLR

TINF2

351

Q9BSI4
CKETDMLNYLIECFD

UBE4B

421

O95155
EKVNMYCVTDDQLIC

MID1

181

O15344
FFKEEELEYNCQMCK

USP29

476

Q9HBJ7
QMGEEDKEYVCVKCC

PHF3

756

Q92576
DVDQYIMCYEECNKI

PRSS42P

221

Q7Z5A4
CENLQLRKYCKSMDE

ZNF492

76

Q9P255
SEYQNMTVDILCNDC

RCHY1

211

Q96PM5
EGQQYCCRLVEMDSK

TTC37

256

Q6PGP7
LPCEEDEMCVNYNDQ

TMEM207

31

Q6UWW9
EKVNMYCVSDDQLIC

MID2

201

Q9UJV3
VYRTAVCIENSCMEK

POSTN

461

Q15063
EKHNDICAICYQDMK

RNF145

531

Q96MT1
EFSEVVMKLEECLCN

TNNI3K

711

Q59H18
YEEDLQNLCDKTQMS

ZHX3

861

Q9H4I2
CMEEICSYEEVKEVF

PRRG3

36

Q9BZD7
MCNEETEIKEAQSYQ

TSHZ1

46

Q6ZSZ6
MDCIIAEIKAQYDDI

KRT81

271

Q14533
MDSNIIQKDAEYENC

NLRP14

461

Q86W24
SECDFKVENAMDCLL

N4BP2

71

Q86UW6