Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor activity	TAF3 TAF9B TAF1 SNAPC4 TAF1L	4.77e-06	52	95	5	GO:0016251
GeneOntologyMolecularFunction	general transcription initiation factor activity	TAF3 TAF9B TAF1 SNAPC4 TAF1L	1.80e-05	68	95	5	GO:0140223
GeneOntologyMolecularFunction	spectrin binding	ANK3 GBP1 GBP2 GBP3	2.00e-05	34	95	4	GO:0030507
GeneOntologyMolecularFunction	GDP phosphatase activity	GBP1 GBP2 GBP3	2.22e-05	12	95	3	GO:0004382
GeneOntologyMolecularFunction	molecular function inhibitor activity	GBP1 GBP2 GBP3 ADGRV1 CAV3 LCN1 ITPR1 THBS1 TAF3 TAF1 CABIN1 TAF1L	2.56e-05	596	95	12	GO:0140678
GeneOntologyMolecularFunction	protein dimerization activity	TCF12 GBP7 MYO9B GBP1 GBP2 GBP3 THBS1 TAF3 TAF9B SMC3 TAF1 DIAPH3 STARD3NL ALDH3A2 TAF1L SNX1 PML	4.86e-05	1205	95	17	GO:0046983
GeneOntologyMolecularFunction	modification-dependent protein binding	ANKRD13D ANK3 HTATSF1 TAF1 PLCG2 TAF1L PML	5.76e-05	206	95	7	GO:0140030
GeneOntologyMolecularFunction	nucleoside diphosphate phosphatase activity	GBP1 GBP2 GBP3	1.12e-04	20	95	3	GO:0017110
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	2.22e-04	5	95	2	GO:0061628
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO9B DNAH12 KIF3B SMC3 KIF3C	2.51e-04	118	95	5	GO:0003774
GeneOntologyMolecularFunction	microtubule motor activity	DNAH12 KIF3B SMC3 KIF3C	3.47e-04	70	95	4	GO:0003777
GeneOntologyMolecularFunction	protein heterodimerization activity	TCF12 TAF3 TAF9B SMC3 TAF1 TAF1L SNX1 PML	6.23e-04	398	95	8	GO:0046982
GeneOntologyMolecularFunction	transcription regulator inhibitor activity	TAF3 TAF1 TAF1L	6.65e-04	36	95	3	GO:0140416
GeneOntologyMolecularFunction	chromatin binding	LEMD3 ASH1L NCAPH PRDM11 SMC3 SUPT6H TAF1 CABIN1 TAF1L TOP1 RAD21	7.66e-04	739	95	11	GO:0003682
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	7.89e-04	9	95	2	GO:0001181
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK3 PLCG2	9.83e-04	10	95	2	GO:0140031
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	HSP90B1 GBP7 MYO9B GBP1 GBP2 GBP3 SRCAP DNAH12 KIF3B SMC3 KIF3C	1.13e-03	775	95	11	GO:0017111
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	STK36 SIK3 TTK SYK PRKCZ TAF1 TAF1L TOP1	1.30e-03	446	95	8	GO:0004674
GeneOntologyMolecularFunction	lipopolysaccharide binding	GBP1 GBP2 GBP3	1.55e-03	48	95	3	GO:0001530
GeneOntologyMolecularFunction	protein homodimerization activity	GBP7 MYO9B GBP1 GBP2 GBP3 THBS1 DIAPH3 STARD3NL ALDH3A2 SNX1 PML	1.68e-03	815	95	11	GO:0042803
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	GBP1 GBP2 GBP3 LCN1 THBS1	1.70e-03	180	95	5	GO:0004866
GeneOntologyMolecularFunction	histone acetyltransferase activity	SRCAP TAF1 TAF1L	1.84e-03	51	95	3	GO:0004402
GeneOntologyMolecularFunction	peptidase inhibitor activity	GBP1 GBP2 GBP3 LCN1 THBS1	2.00e-03	187	95	5	GO:0030414
GeneOntologyMolecularFunction	cytoskeletal protein binding	CCDC170 ANK3 MYO9B GBP1 GBP2 GBP3 ADGRV1 CAV3 KIF3B SMC3 AIF1 KIF3C DIAPH3	2.07e-03	1099	95	13	GO:0008092
GeneOntologyMolecularFunction	pyrophosphatase activity	HSP90B1 GBP7 MYO9B GBP1 GBP2 GBP3 SRCAP DNAH12 KIF3B SMC3 KIF3C	2.11e-03	839	95	11	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	HSP90B1 GBP7 MYO9B GBP1 GBP2 GBP3 SRCAP DNAH12 KIF3B SMC3 KIF3C	2.13e-03	840	95	11	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	HSP90B1 GBP7 MYO9B GBP1 GBP2 GBP3 SRCAP DNAH12 KIF3B SMC3 KIF3C	2.13e-03	840	95	11	GO:0016818
GeneOntologyMolecularFunction	cell adhesion molecule binding	ANK3 DSC2 THBS1 SYK DIAPH3 CDH2 GCN1 CDH4 SNX1	2.20e-03	599	95	9	GO:0050839
GeneOntologyMolecularFunction	protein kinase activity	STK36 SIK3 TTK SYK PRKCZ TAF1 TAF1L TOP1 EPHB1	2.23e-03	600	95	9	GO:0004672
GeneOntologyMolecularFunction	Hsp90 protein binding	GBP1 GBP2 GBP3	2.29e-03	55	95	3	GO:0051879
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	SRCAP TAF1 TAF1L	2.29e-03	55	95	3	GO:0061733
GeneOntologyMolecularFunction	endopeptidase regulator activity	GBP1 GBP2 GBP3 LCN1 THBS1	2.74e-03	201	95	5	GO:0061135
GeneOntologyMolecularFunction	G protein activity	GBP1 GBP2 GBP3	2.80e-03	59	95	3	GO:0003925
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	SRCAP TAF1 TAF1L	2.93e-03	60	95	3	GO:0034212
GeneOntologyMolecularFunction	calcium ion binding	HSP90B1 DSC2 ADGRV1 C2CD5 ITPR1 THBS1 TCHH AIF1 CDH2 CDH4	2.97e-03	749	95	10	GO:0005509
GeneOntologyMolecularFunction	enzyme inhibitor activity	GBP1 GBP2 GBP3 ADGRV1 LCN1 THBS1 CABIN1	4.73e-03	435	95	7	GO:0004857
GeneOntologyMolecularFunction	nitric-oxide synthase binding	CAV3 CDH2	4.86e-03	22	95	2	GO:0050998
GeneOntologyMolecularFunction	ATP hydrolysis activity	HSP90B1 MYO9B SRCAP DNAH12 KIF3B SMC3 KIF3C	5.10e-03	441	95	7	GO:0016887
GeneOntologyBiologicalProcess	cytolysis in another organism	GBP7 GBP1 GBP2 GBP3	5.45e-08	9	96	4	GO:0051715
GeneOntologyBiologicalProcess	positive regulation of pyroptotic inflammatory response	GBP7 GBP1 GBP2 GBP3	5.45e-08	9	96	4	GO:0140639
GeneOntologyBiologicalProcess	cytolysis	GBP7 GBP1 GBP2 GBP3	2.12e-07	12	96	4	GO:0019835
GeneOntologyBiologicalProcess	positive regulation of AIM2 inflammasome complex assembly	GBP1 GBP2 GBP3	3.90e-07	4	96	3	GO:0140973
GeneOntologyBiologicalProcess	regulation of interleukin-10 production	TNFRSF21 SASH3 SYK PRKCZ PLCG2 RAD21	1.25e-06	74	96	6	GO:0032653
GeneOntologyBiologicalProcess	interleukin-10 production	TNFRSF21 SASH3 SYK PRKCZ PLCG2 RAD21	1.58e-06	77	96	6	GO:0032613
GeneOntologyBiologicalProcess	regulation of AIM2 inflammasome complex assembly	GBP1 GBP2 GBP3	1.93e-06	6	96	3	GO:0140971
GeneOntologyBiologicalProcess	adhesion of symbiont to host	GBP7 GBP1 GBP2 GBP3	2.02e-06	20	96	4	GO:0044406
GeneOntologyBiologicalProcess	positive regulation of interleukin-10 production	SASH3 SYK PRKCZ PLCG2 RAD21	2.87e-06	48	96	5	GO:0032733
GeneOntologyBiologicalProcess	AIM2 inflammasome complex assembly	GBP1 GBP2 GBP3	5.38e-06	8	96	3	GO:0140970
GeneOntologyBiologicalProcess	positive regulation of inflammasome-mediated signaling pathway	GBP1 GBP2 GBP3 PLCG2	6.09e-06	26	96	4	GO:0141087
GeneOntologyBiologicalProcess	microtubule-based process	CCDC170 STK36 ANK3 CNTRL ASH1L SIK3 CAV3 TTK DNAH12 KIF3B SMC3 WASHC5 ZPR1 KIF3C PRKCZ DIAPH3 ARHGAP21	6.97e-06	1058	96	17	GO:0007017
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	NES SETX GBP1 GBP2 GBP3 CAV3 NCAPH C2CD5 ITPR1 WASHC5 DDHD1 RAB3GAP2 SYK KIF3C PLCG2 CDH4 PML RAD21 EPHB1	1.47e-05	1366	96	19	GO:0051130
GeneOntologyBiologicalProcess	maintenance of location in cell	HSP90B1 ANK3 ITPR1 TAF3 OS9 PLCG2 ARHGAP21 PML	2.84e-05	259	96	8	GO:0051651
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	CCDC170 STK36 ANK3 CNTRL SIK3 CAV3 TTK KIF3B SMC3 WASHC5 ZPR1 PRKCZ DIAPH3	2.87e-05	720	96	13	GO:0000226
GeneOntologyBiologicalProcess	defense response to protozoan	GBP7 GBP1 GBP2 GBP3	3.20e-05	39	96	4	GO:0042832
GeneOntologyBiologicalProcess	cellular response to interferon-beta	GBP7 GBP1 GBP2 GBP3	3.91e-05	41	96	4	GO:0035458
GeneOntologyBiologicalProcess	protein localization to organelle	TOR1AIP2 MIA3 ZFYVE16 TNPO2 GBP1 GBP2 TTK TAF3 ZPR1 RAB3GAP2 SYK HTATSF1 OS9 PRKCZ PML RAD21	4.10e-05	1091	96	16	GO:0033365
GeneOntologyBiologicalProcess	response to protozoan	GBP7 GBP1 GBP2 GBP3	4.31e-05	42	96	4	GO:0001562
GeneOntologyBiologicalProcess	pyroptotic inflammatory response	GBP7 GBP1 GBP2 GBP3	4.31e-05	42	96	4	GO:0070269
GeneOntologyBiologicalProcess	intracellular transport	HSP90B1 MIA3 ANK3 ZFYVE16 TNPO2 SIL1 C2CD5 KIF3B WASHC5 SUPT6H ZPR1 RAB3GAP2 SYK OS9 PRKCZ DIAPH3 ARHGAP21 SNX1 PML	5.14e-05	1496	96	19	GO:0046907
GeneOntologyBiologicalProcess	protein targeting	ANK3 ZFYVE16 GBP1 GBP2 GBP3 SIL1 C2CD5 OS9 PML	6.10e-05	373	96	9	GO:0006605
GeneOntologyBiologicalProcess	regulation of inflammasome-mediated signaling pathway	GBP1 GBP2 GBP3 PLCG2	7.33e-05	48	96	4	GO:0141085
GeneOntologyBiologicalProcess	response to interferon-beta	GBP7 GBP1 GBP2 GBP3	7.33e-05	48	96	4	GO:0035456
GeneOntologyBiologicalProcess	inflammasome-mediated signaling pathway	GBP1 GBP2 GBP3 PLCG2	1.08e-04	53	96	4	GO:0141084
GeneOntologyBiologicalProcess	establishment of meiotic sister chromatid cohesion	SMC3 RAD21	1.28e-04	4	96	2	GO:0034089
GeneOntologyBiologicalProcess	cellular response to type II interferon	GBP7 GBP1 GBP2 GBP3 AIF1	1.93e-04	114	96	5	GO:0071346
GeneOntologyBiologicalProcess	response to magnesium ion	ANK3 THBS1 PLCG2	2.09e-04	25	96	3	GO:0032026
GeneOntologyBiologicalProcess	membrane organization	TOR1AIP2 MIA3 ANK3 LEMD3 CAV3 C2CD5 THBS1 SYNJ2 AIF1 PLCG2 DIAPH3 EXOC7 CDH2	3.12e-04	914	96	13	GO:0061024
GeneOntologyBiologicalProcess	regulation of membrane depolarization during cardiac muscle cell action potential	ANK3 CAV3	3.18e-04	6	96	2	GO:1900825
GeneOntologyBiologicalProcess	chromosome segregation	NCAPH TTK KIF3B SMC3 WASHC5 DPF3 DIAPH3 TOP1 RAD21	3.19e-04	465	96	9	GO:0007059
GeneOntologyBiologicalProcess	cell cycle process	NES ANK3 NCAPH TTK KIF3B SMC3 WASHC5 DPF3 ZPR1 AIF1 TAF1 PLCG2 DIAPH3 EXOC7 TOP1 PML RAD21	3.25e-04	1441	96	17	GO:0022402
GeneOntologyBiologicalProcess	killing of cells of another organism	GBP7 GBP1 GBP2 GBP3 SYK	3.43e-04	129	96	5	GO:0031640
GeneOntologyBiologicalProcess	disruption of cell in another organism	GBP7 GBP1 GBP2 GBP3 SYK	3.43e-04	129	96	5	GO:0141061
GeneOntologyBiologicalProcess	positive regulation of interleukin-4 production	SASH3 SYK PRKCZ	3.62e-04	30	96	3	GO:0032753
GeneOntologyBiologicalProcess	disruption of anatomical structure in another organism	GBP7 GBP1 GBP2 GBP3 SYK	3.82e-04	132	96	5	GO:0141060
GeneOntologyBiologicalProcess	cell division	ANK3 CNTRL NCAPH KIF3B SMC3 WASHC5 DCLRE1A DIAPH3 EXOC7 TOP1 RAD21	3.94e-04	697	96	11	GO:0051301
GeneOntologyBiologicalProcess	detection of mechanical stimulus	ADGRV1 CAV3 PIEZO2 CDH2	4.16e-04	75	96	4	GO:0050982
GeneOntologyBiologicalProcess	maintenance of protein location in cell	ANK3 TAF3 OS9 PML	4.37e-04	76	96	4	GO:0032507
GeneOntologyBiologicalProcess	detection of muscle stretch	CAV3 CDH2	4.43e-04	7	96	2	GO:0035995
GeneOntologyBiologicalProcess	establishment of mitotic sister chromatid cohesion	SMC3 RAD21	4.43e-04	7	96	2	GO:0034087
GeneOntologyBiologicalProcess	regulation of membrane depolarization during action potential	ANK3 CAV3	4.43e-04	7	96	2	GO:0098902
GeneOntologyBiologicalProcess	endocytosis	ANKRD13D ANK3 ZFYVE16 CAV3 THBS1 SYNJ2 WASHC5 SYK AIF1 PLCG2 ARHGAP21 SNX1	4.52e-04	827	96	12	GO:0006897
GeneOntologyBiologicalProcess	macrophage activation	CALHM2 THBS1 SYK AIF1 PLCG2	5.00e-04	140	96	5	GO:0042116
GeneOntologyBiologicalProcess	positive regulation of pattern recognition receptor signaling pathway	GBP1 GBP2 GBP3 PLCG2	5.07e-04	79	96	4	GO:0062208
GeneOntologyBiologicalProcess	response to type II interferon	GBP7 GBP1 GBP2 GBP3 AIF1	5.16e-04	141	96	5	GO:0034341
GeneOntologyBiologicalProcess	maintenance of location	HSP90B1 ANK3 ITPR1 TAF3 OS9 PLCG2 ARHGAP21 PML	5.24e-04	396	96	8	GO:0051235
GeneOntologyBiologicalProcess	response to organophosphorus	HSP90B1 HCN1 ITPR1 TAF1 PLCG2	5.33e-04	142	96	5	GO:0046683
GeneOntologyBiologicalProcess	regulation of action potential	ANK3 DSC2 HCN1 CAV3	5.57e-04	81	96	4	GO:0098900
GeneOntologyBiologicalProcess	female meiosis chromosome segregation	NCAPH TTK	5.89e-04	8	96	2	GO:0016321
GeneOntologyBiologicalProcess	intracellular protein transport	HSP90B1 ZFYVE16 TNPO2 SIL1 C2CD5 ZPR1 RAB3GAP2 SYK OS9 SNX1 PML	6.49e-04	740	96	11	GO:0006886
GeneOntologyBiologicalProcess	positive regulation of protein-containing complex assembly	GBP1 GBP2 GBP3 CAV3 SYK PLCG2	6.76e-04	227	96	6	GO:0031334
GeneOntologyBiologicalProcess	protein-DNA complex organization	ASH1L SRCAP TAF3 SUPT6H DPF3 APOBEC2 HTATSF1 TAF1 CABIN1 TAF1L TOP1 PML RAD21	7.23e-04	999	96	13	GO:0071824
GeneOntologyBiologicalProcess	DNA-templated transcription initiation	SETX TAF3 TAF9B APOBEC2 TAF1 TAF1L	7.41e-04	231	96	6	GO:0006352
GeneOntologyBiologicalProcess	regulation of interleukin-4 production	SASH3 SYK PRKCZ	7.91e-04	39	96	3	GO:0032673
GeneOntologyBiologicalProcess	response to ATP	HSP90B1 TAF1 PLCG2	8.52e-04	40	96	3	GO:0033198
GeneOntologyBiologicalProcess	chromatin organization	ASH1L SRCAP SUPT6H DPF3 APOBEC2 HTATSF1 TAF1 CABIN1 TAF1L TOP1 PML RAD21	9.15e-04	896	96	12	GO:0006325
GeneOntologyCellularComponent	host intracellular region	GBP7 GBP1 GBP2 GBP3	6.22e-09	6	96	4	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP7 GBP1 GBP2 GBP3	6.22e-09	6	96	4	GO:0030430
GeneOntologyCellularComponent	host cell part	GBP7 GBP1 GBP2 GBP3	6.22e-09	6	96	4	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP7 GBP1 GBP2 GBP3	6.22e-09	6	96	4	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP7 GBP1 GBP2 GBP3	6.22e-09	6	96	4	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP7 GBP1 GBP2 GBP3	6.22e-09	6	96	4	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP7 GBP1 GBP2 GBP3	6.22e-09	6	96	4	GO:0020005
GeneOntologyCellularComponent	perinuclear region of cytoplasm	ANKRD13D JCAD HSP90B1 GBP7 MYO9B CNTRL GBP1 GBP2 GBP3 ADGRV1 SRCAP ITPR1 SYNJ2 ZPR1 AIF1 PRKCZ PLCG2 SNX1	2.17e-07	934	96	18	GO:0048471
GeneOntologyCellularComponent	host cellular component	GBP7 GBP1 GBP2 GBP3	5.48e-07	15	96	4	GO:0018995
GeneOntologyCellularComponent	symbiont cell surface	GBP1 GBP2 GBP3	5.17e-06	8	96	3	GO:0106139
GeneOntologyCellularComponent	other organism part	GBP1 GBP2 GBP3	7.73e-06	9	96	3	GO:0044217
GeneOntologyCellularComponent	cell leading edge	JCAD MYO9B HCN1 ADGRV1 C2CD5 SYNJ2 AIF1 PRKCZ PLCG2 CDH2 SNX1	1.85e-05	500	96	11	GO:0031252
GeneOntologyCellularComponent	leading edge membrane	JCAD HCN1 ADGRV1 C2CD5 SYNJ2 AIF1 PLCG2	5.23e-05	210	96	7	GO:0031256
GeneOntologyCellularComponent	transcription factor TFIID complex	TAF3 TAF9B TAF1 TAF1L	6.40e-05	47	96	4	GO:0005669
GeneOntologyCellularComponent	ruffle membrane	JCAD C2CD5 SYNJ2 AIF1 PLCG2	1.41e-04	108	96	5	GO:0032587
GeneOntologyCellularComponent	intercalated disc	ANK3 DSC2 CAV3 CDH2	2.72e-04	68	96	4	GO:0014704
GeneOntologyCellularComponent	ruffle	JCAD MYO9B C2CD5 SYNJ2 AIF1 PLCG2	3.78e-04	206	96	6	GO:0001726
GeneOntologyCellularComponent	meiotic cohesin complex	SMC3 RAD21	4.32e-04	7	96	2	GO:0030893
GeneOntologyCellularComponent	mitotic cohesin complex	SMC3 RAD21	4.32e-04	7	96	2	GO:0030892
GeneOntologyCellularComponent	stereocilia coupling link	ADGRV1 DIAPH3	5.74e-04	8	96	2	GO:0002139
GeneOntologyCellularComponent	sarcoplasmic reticulum	HSP90B1 ANK3 ITPR1 THBS1	7.25e-04	88	96	4	GO:0016529
GeneOntologyCellularComponent	RNA polymerase II, holoenzyme	TAF3 TAF9B TAF1 TAF1L	7.57e-04	89	96	4	GO:0016591
GeneOntologyCellularComponent	cell-cell contact zone	ANK3 DSC2 CAV3 CDH2	9.29e-04	94	96	4	GO:0044291
GeneOntologyCellularComponent	cohesin complex	SMC3 RAD21	1.12e-03	11	96	2	GO:0008278
GeneOntologyCellularComponent	nuclear chromosome	SETX SRCAP NCAPH SMC3 TOP1 RAD21	1.13e-03	254	96	6	GO:0000228
GeneOntologyCellularComponent	actin cytoskeleton	MYO9B GBP1 GBP2 GBP3 AIF1 PRKCZ DIAPH3 CDH2 ARHGAP21	1.33e-03	576	96	9	GO:0015629
GeneOntologyCellularComponent	nuclear DNA-directed RNA polymerase complex	TAF3 TAF9B TAF1 TAF1L	1.83e-03	113	96	4	GO:0055029
GeneOntologyCellularComponent	sarcoplasm	HSP90B1 ANK3 ITPR1 THBS1	1.90e-03	114	96	4	GO:0016528
GeneOntologyCellularComponent	DNA-directed RNA polymerase complex	TAF3 TAF9B TAF1 TAF1L	2.02e-03	116	96	4	GO:0000428
GeneOntologyCellularComponent	RNA polymerase complex	TAF3 TAF9B TAF1 TAF1L	2.22e-03	119	96	4	GO:0030880
GeneOntologyCellularComponent	axon	SETX ANK3 HCN1 TNFRSF21 KIF3B SYNJ2 ZPR1 KIF3C PRKCZ EXOC7 EPHB1	2.57e-03	891	96	11	GO:0030424
GeneOntologyCellularComponent	vesicle membrane	GBP7 ZFYVE16 GBP1 GBP2 GBP3 C2CD5 ITPR1 WASHC5 DIAPH3 STARD3NL ARHGAP21 SNX1 PML EPHB1	2.86e-03	1325	96	14	GO:0012506
GeneOntologyCellularComponent	early endosome membrane	ZFYVE16 WASHC5 SNX1 PML EPHB1	2.96e-03	212	96	5	GO:0031901
GeneOntologyCellularComponent	midbody	HSP90B1 CNTRL KIF3B EXOC7 RAD21	3.61e-03	222	96	5	GO:0030496
GeneOntologyCellularComponent	cell projection membrane	JCAD HCN1 ADGRV1 C2CD5 SYNJ2 AIF1 PLCG2	3.73e-03	431	96	7	GO:0031253
GeneOntologyCellularComponent	filopodium tip	MYO9B EPHB1	3.76e-03	20	96	2	GO:0032433
GeneOntologyCellularComponent	nuclear matrix	SMC3 PRKCZ PML RAD21	3.98e-03	140	96	4	GO:0016363
GeneOntologyCellularComponent	endoplasmic reticulum lumen	HSP90B1 MIA3 SIL1 THBS1 OS9 CDH2	4.30e-03	332	96	6	GO:0005788
GeneOntologyCellularComponent	transferase complex, transferring phosphorus-containing groups	PHKB TAF3 TAF9B PRKCZ TAF1 TAF1L	4.49e-03	335	96	6	GO:0061695
GeneOntologyCellularComponent	proteasome regulatory particle	PSMD2 PSMD3	4.54e-03	22	96	2	GO:0005838
MousePheno	increased susceptibility to parasitic infection induced morbidity/mortality	GBP1 GBP2 GBP3	3.22e-05	11	83	3	MP:0010750
MousePheno	abnormal megakaryocyte progenitor cell number	PRDM11 ARHGAP21	3.48e-05	2	83	2	MP:0020462
MousePheno	abnormal sinus arrhythmia	STK36 HCN1 GBP1 GBP2 GBP3	9.82e-05	78	83	5	MP:0004122
MousePheno	increased heart rate variability	HCN1 GBP1 GBP2 GBP3	9.90e-05	41	83	4	MP:0003928
Domain	GBP_C	GBP7 GBP1 GBP2 GBP3	1.34e-07	10	96	4	PF02841
Domain	G_GB1_RHD3_dom	GBP7 GBP1 GBP2 GBP3	2.10e-07	11	96	4	IPR030386
Domain	Guanylate-bd_C	GBP7 GBP1 GBP2 GBP3	2.10e-07	11	96	4	IPR003191
Domain	GBP	GBP7 GBP1 GBP2 GBP3	2.10e-07	11	96	4	PF02263
Domain	Guanylate-bd_N	GBP7 GBP1 GBP2 GBP3	2.10e-07	11	96	4	IPR015894
Domain	G_GB1_RHD3	GBP7 GBP1 GBP2 GBP3	2.10e-07	11	96	4	PS51715
Domain	Cadherin_pro	DSC2 CDH2 CDH4	4.54e-06	7	96	3	PF08758
Domain	Cadherin_pro_dom	DSC2 CDH2 CDH4	7.23e-06	8	96	3	IPR014868
Domain	Cadherin_pro	DSC2 CDH2 CDH4	7.23e-06	8	96	3	SM01055
Domain	TAF_II_230-bd	TAF1 TAF1L	2.61e-05	2	96	2	IPR009067
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	2.61e-05	2	96	2	IPR022591
Domain	-	TAF1 TAF1L	2.61e-05	2	96	2	1.10.1100.10
Domain	TBP-binding	TAF1 TAF1L	2.61e-05	2	96	2	PF09247
Domain	DUF3591	TAF1 TAF1L	2.61e-05	2	96	2	PF12157
Domain	TAF1_animal	TAF1 TAF1L	2.61e-05	2	96	2	IPR011177
Domain	Cadherin_cytoplasmic-dom	DSC2 CDH2 CDH4	2.79e-04	25	96	3	IPR000233
Domain	Cadherin_C	DSC2 CDH2 CDH4	2.79e-04	25	96	3	PF01049
Domain	P-loop_NTPase	SETX GBP7 MYO9B GBP1 GBP2 GBP3 SRCAP NWD2 DNAH12 KIF3B SMC3 YLPM1 KIF3C	3.92e-04	848	96	13	IPR027417
Domain	Catenin_binding_dom	DSC2 CDH2 CDH4	4.36e-04	29	96	3	IPR027397
Domain	-	DSC2 CDH2 CDH4	4.36e-04	29	96	3	4.10.900.10
Domain	S1	ZCCHC17 SUPT6H	7.17e-04	8	96	2	PF00575
Domain	BROMODOMAIN_1	ASH1L TAF1 TAF1L	9.01e-04	37	96	3	PS00633
Domain	Bromodomain	ASH1L TAF1 TAF1L	9.74e-04	38	96	3	PF00439
Domain	S1	ZCCHC17 SUPT6H	1.15e-03	10	96	2	PS50126
Domain	BROMODOMAIN_2	ASH1L TAF1 TAF1L	1.22e-03	41	96	3	PS50014
Domain	BROMO	ASH1L TAF1 TAF1L	1.31e-03	42	96	3	SM00297
Domain	Bromodomain	ASH1L TAF1 TAF1L	1.31e-03	42	96	3	IPR001487
Domain	-	ASH1L TAF1 TAF1L	1.31e-03	42	96	3	1.20.920.10
Domain	S1	ZCCHC17 SUPT6H	1.67e-03	12	96	2	SM00316
Domain	S1_dom	ZCCHC17 SUPT6H	1.67e-03	12	96	2	IPR022967
Domain	S1_domain	ZCCHC17 SUPT6H	1.67e-03	12	96	2	IPR003029
Domain	ARM-type_fold	STK36 TNPO2 PSMD2 SIL1 ITPR1 DIAPH3 GCN1	1.83e-03	339	96	7	IPR016024
Domain	HEAT	STK36 TNPO2 GCN1	1.92e-03	48	96	3	PF02985
Domain	ARM-like	STK36 SETX TNPO2 PSMD2 SIL1 GCN1	2.70e-03	270	96	6	IPR011989
Domain	HEAT	STK36 TNPO2 GCN1	3.31e-03	58	96	3	IPR000357
Domain	-	SETX GBP7 GBP1 GBP2 GBP3 SRCAP NWD2 DNAH12 SMC3 YLPM1	4.97e-03	746	96	10	3.40.50.300
Pathway	KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY	ITPR1 SYK PLCG2	1.39e-05	9	79	3	M47852
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	TAF3 TAF9B SUPT6H TAF1 TAF1L	8.93e-05	81	79	5	M865
Pathway	REACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS	TAF3 TAF9B SUPT6H TAF1 TAF1L	1.00e-04	83	79	5	MM15314
Pathway	REACTOME_HIV_TRANSCRIPTION_INITIATION	TAF3 TAF9B TAF1 TAF1L	1.36e-04	47	79	4	M29568
Pathway	REACTOME_RNA_POLYMERASE_II_PROMOTER_ESCAPE	TAF3 TAF9B TAF1 TAF1L	1.47e-04	48	79	4	MM15424
Pathway	WP_KCNQ2RELATED_EPILEPSIES	ANK3 ITPR1 PLCG2	1.54e-04	19	79	3	M48320
Pathway	REACTOME_INTERFERON_GAMMA_SIGNALING	GBP7 GBP1 GBP2 GBP3 PML	2.20e-04	98	79	5	M965
Pathway	REACTOME_CLEC7A_DECTIN_1_SIGNALING	PSMD2 PSMD3 ITPR1 SYK PLCG2	2.42e-04	100	79	5	M27467
Pathway	REACTOME_MYOGENESIS	TCF12 CDH2 CDH4	3.15e-04	24	79	3	MM15174
Pubmed	Essential Role of mGBP7 for Survival of Toxoplasma gondii Infection.	GBP7 GBP1 GBP2 GBP3	2.84e-10	5	97	4	31964735
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	HSP90B1 SETX PSMD2 PSMD3 NCAPH TTK SMC3 YLPM1 SF3A3 DIAPH3 EXOC7 GCN1 TOP1 RAD21	9.06e-10	582	97	14	20467437
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	HSP90B1 ANK3 DSC2 ZFYVE16 PSMD2 PSMD3 TTK SMC3 RAB3GAP2 TCF25 DIAPH3 ALDH3A2 GCN1 TOP1 ARHGAP21	1.22e-09	708	97	15	39231216
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	JCAD STK36 HSP90B1 CNTRL GBP2 PSMD2 PSMD3 NCAPH ITPR1 SUPT6H SF3A3 HTATSF1 PLCG2 ARHGAP21 SNX1	2.86e-09	754	97	15	35906200
Pubmed	In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.	GBP7 GBP1 GBP2 GBP3	3.95e-09	8	97	4	16689661
Pubmed	Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.	GBP7 GBP1 GBP2 GBP3	7.09e-09	9	97	4	24739961
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	NES GBP1 GBP2 GBP3	1.18e-08	10	97	4	28334111
Pubmed	Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.	GBP7 GBP1 GBP2 GBP3	1.85e-08	11	97	4	24715728
Pubmed	Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.	GBP7 GBP1 GBP2 GBP3	1.85e-08	11	97	4	18025219
Pubmed	GTPase properties of the interferon-induced human guanylate-binding protein 2.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	8706832
Pubmed	Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	32620042
Pubmed	[Guanylate-binding protein 2 regulates the maturation of mouse dendritic cells induced by β-glucan].	GBP1 GBP2 GBP3	2.10e-08	3	97	3	29089068
Pubmed	Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	1715024
Pubmed	Two families of GTPases dominate the complex cellular response to IFN-gamma.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	9862701
Pubmed	The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	11726669
Pubmed	GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	38636926
Pubmed	Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	15717119
Pubmed	Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	35383115
Pubmed	Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	20950129
Pubmed	Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	30062052
Pubmed	Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	26416908
Pubmed	Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	32354743
Pubmed	Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	23248289
Pubmed	Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	36639389
Pubmed	The interferon-induced GTPase, mGBP-2, confers resistance to paclitaxel-induced cytotoxicity without inhibiting multinucleation.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	16914101
Pubmed	The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.	GBP1 GBP2 GBP3	2.10e-08	3	97	3	22730319
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TOR1AIP2 HSP90B1 MIA3 ANK3 DSC2 LEMD3 SIK3 TTK C2CD5 ITPR1 SUPT6H RAB3GAP2 HTATSF1 OS9 DIAPH3 ALDH3A2 SNX1 PML RAD21	2.53e-08	1487	97	19	33957083
Pubmed	Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.	GBP7 GBP1 GBP2 GBP3	2.77e-08	12	97	4	35906252
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	TOR1AIP2 MIA3 SETX ANK3 GBP7 CNTRL FRMPD1 ASH1L SRCAP C2CD5 ITPR1 PHKB DDHD1 PRKCZ ARHGAP21 PML	5.29e-08	1084	97	16	11544199
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	HSP90B1 MIA3 ANK3 ZFYVE16 LEMD3 TTK ALDH3A2 GCN1 ARHGAP21	5.64e-08	263	97	9	34702444
Pubmed	cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.	GBP1 GBP2 GBP3	8.40e-08	4	97	3	8917111
Pubmed	The Furin Protease Dependence and Antiviral GBP2 Sensitivity of Murine Leukemia Virus Infection Are Determined by the Amino Acid Sequence at the Envelope Glycoprotein Cleavage Site.	GBP1 GBP2 GBP3	8.40e-08	4	97	3	39337476
Pubmed	Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.	GBP1 GBP2 GBP3	8.40e-08	4	97	3	7823961
Pubmed	Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis.	GBP1 GBP2 GBP3	8.40e-08	4	97	3	36609599
Pubmed	Genomic organization and chromosomal localization of a new member of the murine interferon-induced guanylate-binding protein family.	GBP1 GBP2 GBP3	8.40e-08	4	97	3	10386861
Pubmed	Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.	GBP1 GBP2 GBP3	8.40e-08	4	97	3	38404575
Pubmed	A human MAP kinase interactome.	HSP90B1 SETX ANK3 CNTRL SIK3 SMC3 SYNJ2 OS9 PRKCZ TAF1 GCN1	1.20e-07	486	97	11	20936779
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NES MIA3 ESS2 ZFYVE16 LEMD3 SYNJ2 DDHD1 RAB3GAP2 YLPM1 SF3A3 OS9 DCLRE1A EXOC7	1.34e-07	733	97	13	34672954
Pubmed	Murine GBP-2: a new IFN-gamma-induced member of the GBP family of GTPases isolated from macrophages.	GBP1 GBP2 GBP3	2.09e-07	5	97	3	9858320
Pubmed	TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2.	GBP1 GBP2 GBP3	2.09e-07	5	97	3	30858199
Pubmed	Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro.	GBP1 GBP2 GBP3	2.09e-07	5	97	3	12396730
Pubmed	Unique features of different members of the human guanylate-binding protein family.	GBP1 GBP2 GBP3	2.09e-07	5	97	3	17266443
Pubmed	Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.	GBP1 GBP2 GBP3	2.09e-07	5	97	3	21151871
Pubmed	A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.	GBP7 GBP1 GBP2 GBP3	2.13e-07	19	97	4	21551061
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TOR1AIP2 JCAD HSP90B1 MIA3 ANK3 ZFYVE16 LEMD3 PSMD2 PSMD3 ITPR1 PHKB WASHC5 YLPM1 ALDH3A2 GCN1	2.17e-07	1049	97	15	27880917
Pubmed	An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.	GBP7 GBP1 GBP2 GBP3	3.28e-07	21	97	4	19158679
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	HSP90B1 UAP1 MIA3 ANK3 CNTRL ASH1L GBP3 PSMD2 PSMD3 SRCAP GCN1 PGM2 TOP1	3.99e-07	807	97	13	30575818
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ANK3 SRCAP NCAPH TAF3 TAF9B RAB3GAP2 YLPM1 TAF1 DIAPH3 GCN1 SNX1	4.01e-07	549	97	11	38280479
Pubmed	Human transcription factor protein interaction networks.	TCF12 ESS2 TNPO2 PSMD2 PSMD3 SRCAP TAF3 TAF9B SMC3 DPF3 YLPM1 TAF1 CABIN1 TAF1L TOP1 PML RAD21	4.15e-07	1429	97	17	35140242
Pubmed	Immunity-related GTPase M (IRGM) proteins influence the localization of guanylate-binding protein 2 (GBP2) by modulating macroautophagy.	GBP1 GBP2 GBP3	4.18e-07	6	97	3	21757726
Pubmed	Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.	GBP1 GBP2 GBP3	4.18e-07	6	97	3	17293456
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TOR1AIP2 TCF12 DSC2 ASH1L SIK3 SRCAP C2CD5 TAF3 TCHH TAF9B DPF3 TCF25 TAF1 TOP1 PML	4.75e-07	1116	97	15	31753913
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	LEMD3 LCN1 TTK ITPR1 PHKB THBS1 SMC3 SYNJ2 WASHC5 YLPM1 SF3A3 HTATSF1 ALDH3A2 GCN1 RAD21	7.30e-07	1155	97	15	20360068
Pubmed	TRIF signaling is required for caspase-11-dependent immune responses and lethality in sepsis.	GBP1 GBP2 GBP3	7.30e-07	7	97	3	30587103
Pubmed	The interferon-gamma-induced GTPase, mGBP-2, inhibits tumor necrosis factor alpha (TNF-alpha) induction of matrix metalloproteinase-9 (MMP-9) by inhibiting NF-kappaB and Rac protein.	GBP1 GBP2 GBP3	7.30e-07	7	97	3	21502320
Pubmed	The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase.	GBP1 GBP2 GBP3	7.30e-07	7	97	3	20505078
Pubmed	Functional proteomics mapping of a human signaling pathway.	ANK3 ZFYVE16 LEMD3 ASH1L SIL1 KIF3B YLPM1 HTATSF1 OS9 PLCG2 DIAPH3	8.27e-07	591	97	11	15231748
Pubmed	The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.	TAF3 TAF1 TAF1L	1.75e-06	9	97	3	12665565
Pubmed	Osteoclast fusion and bone loss are restricted by interferon inducible guanylate binding proteins.	GBP1 GBP2 GBP3	1.75e-06	9	97	3	33479228
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SETX TCF12 ANK3 DSC2 LEMD3 CNTRL ZCCHC17 NCAPH DCLRE1A GCN1 ARHGAP21 SNX1	1.79e-06	777	97	12	35844135
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HSP90B1 ZFYVE16 SRCAP NCAPH YLPM1 HTATSF1 ALDH3A2 GCN1 TOP1 ARHGAP21 SNX1 PML RAD21	2.02e-06	934	97	13	33916271
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JCAD HSP90B1 ANK3 TNPO2 HCN1 ASH1L PSMD2 THBS1 YLPM1 TAF1 EXOC7 CABIN1 TOP1 ARHGAP21 SNX1	2.72e-06	1285	97	15	35914814
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	TOR1AIP2 ZFYVE16 LEMD3 PSMD2 PSMD3 SIL1 C2CD5 SMC3 SF3A3 OS9 DIAPH3 ALDH3A2 GCN1	3.20e-06	974	97	13	28675297
Pubmed	Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain.	NES CDH2 CDH4	3.41e-06	11	97	3	9367432
Pubmed	IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.	GBP1 GBP2 GBP3	3.41e-06	11	97	3	27693356
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	HSP90B1 ESS2 PSMD2 PSMD3 ZCCHC17 NCAPH TTK TAF3 TAF9B SMC3 WASHC5 SF3A3 GCN1 TOP1 RAD21	3.70e-06	1318	97	15	30463901
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	NES HSP90B1 ANK3 TNPO2 PSMD2 PSMD3 NCAPH PHKB SMC3 RAB3GAP2 SF3A3 EXOC7 GCN1 TOP1	3.71e-06	1149	97	14	35446349
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	TNPO2 PSMD2 PSMD3 SMC3 SUPT6H RAB3GAP2 TCF25 ALDH3A2 EXOC7 RAD21	3.88e-06	560	97	10	35241646
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	TOR1AIP2 MIA3 DSC2 LEMD3 TTK ITPR1 RAB3GAP2 ALDH3A2 GCN1 SNX1	4.40e-06	568	97	10	37774976
Pubmed	Defining the membrane proteome of NK cells.	HSP90B1 MIA3 MYO9B CNTRL PSMD2 PSMD3 NCAPH TTK ITPR1 KIF3B STARD3NL EXOC7 GCN1 RAD21	4.48e-06	1168	97	14	19946888
Pubmed	LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.	GBP1 GBP2 GBP3	4.54e-06	12	97	3	29459437
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	TOR1AIP2 HSP90B1 MIA3 ESS2 ZFYVE16 LEMD3 TTK SIL1 C2CD5 TAF9B OS9 ALDH3A2 SNX1	4.59e-06	1007	97	13	34597346
Pubmed	Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin.	THBS1 SYK PLCG2	7.49e-06	14	97	3	33619517
Pubmed	Ephrin B1 maintains apical adhesion of neural progenitors.	NES CDH2 EPHB1	7.49e-06	14	97	3	23578932
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	HSP90B1 ITPR1 PHKB THBS1 NWD2 WASHC5 SUPT6H TOP1 RAD21	7.57e-06	475	97	9	31040226
Pubmed	Activities of SYK and PLCgamma2 predict apoptotic response of CLL cells to SRC tyrosine kinase inhibitor dasatinib.	SYK PLCG2	7.70e-06	2	97	2	20068106
Pubmed	Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.	CDH2 CDH4	7.70e-06	2	97	2	8247017
Pubmed	Dimerization and its role in GMP formation by human guanylate binding proteins.	GBP1 GBP2	7.70e-06	2	97	2	20923658
Pubmed	The tyrosine kinase Syk is required for light chain isotype exclusion but dispensable for the negative selection of B cells.	SYK PLCG2	7.70e-06	2	97	2	15048721
Pubmed	Xid-like phenotypes: a B cell signalosome takes shape.	SYK PLCG2	7.70e-06	2	97	2	10933389
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	7.70e-06	2	97	2	38804708
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	7.70e-06	2	97	2	22842574
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	7.70e-06	2	97	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	7.70e-06	2	97	2	34403156
Pubmed	Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins.	GBP1 GBP2	7.70e-06	2	97	2	23086406
Pubmed	Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine.	GBP1 GBP2	7.70e-06	2	97	2	20483731
Pubmed	Characterization of a DNA exit gate in the human cohesin ring.	SMC3 RAD21	7.70e-06	2	97	2	25414306
Pubmed	The interferon-inducible GBP1 gene: structure and mapping to human chromosome 1.	GBP1 GBP3	7.70e-06	2	97	2	7518790
Pubmed	Initiation and maintenance of pluripotency gene expression in the absence of cohesin.	SMC3 RAD21	7.70e-06	2	97	2	25561493
Pubmed	Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue.	GBP1 GBP2	7.70e-06	2	97	2	36460216
Pubmed	Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.	SYK PLCG2	7.70e-06	2	97	2	24489640
Pubmed	RAD21 and KIAA0196 at 8q24 are amplified and overexpressed in prostate cancer.	WASHC5 RAD21	7.70e-06	2	97	2	14603436
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	7.70e-06	2	97	2	10070062
Pubmed	Functional cis-heterodimers of N- and R-cadherins.	CDH2 CDH4	7.70e-06	2	97	2	10662782
Pubmed	Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.	SYK PLCG2	7.70e-06	2	97	2	12470302
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SETX ESS2 SRCAP TAF3 SMC3 TAF1 SNAPC4 CABIN1 TOP1 RAD21	7.97e-06	608	97	10	36089195
Pubmed	Mapping of quantitative trait loci determining NK cell-mediated resistance to MHC class I-deficient bone marrow grafts in perforin-deficient mice.	GBP1 GBP2 GBP3	9.34e-06	15	97	3	17114464
Pubmed	Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.	GBP1 GBP2 GBP3	9.34e-06	15	97	3	25774716
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	NES HSP90B1 SETX ZCCHC17 SIK3 SRCAP TAF3 NWD2 SUPT6H YLPM1 SF3A3 GCN1 TOP1	9.89e-06	1082	97	13	38697112
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZFYVE16 SRCAP KIF3B SYNJ2 CABIN1	1.12e-05	104	97	5	9205841
Interaction	CITED1 interactions	STK36 SETX MYO9B SMC3 RAD21	8.98e-07	37	97	5	int:CITED1
Interaction	DERL1 interactions	TOR1AIP2 HSP90B1 MIA3 DSC2 LEMD3 PSMD2 PSMD3 ITPR1 RAB3GAP2 TCF25 ALDH3A2 PML	1.82e-06	453	97	12	int:DERL1
Interaction	EGLN3 interactions	JCAD SETX TCF12 ESS2 ZFYVE16 LEMD3 PSMD2 PSMD3 SIK3 NCAPH TTK SMC3 DDHD1 TCF25 OS9 DIAPH3 EXOC7 GCN1 ARHGAP21 PML	2.94e-06	1296	97	20	int:EGLN3
Interaction	RIPK4 interactions	STK36 HSP90B1 MIA3 ESS2 ANK3 LEMD3 TNPO2 TTK SMC3 TCF25 GCN1	9.92e-06	446	97	11	int:RIPK4
Interaction	TAF4 interactions	TCF12 TAF3 TAF9B SF3A3 TAF1 TAF1L PML	1.04e-05	156	97	7	int:TAF4
Interaction	GBP3 interactions	GBP1 GBP2 GBP3	1.27e-05	10	97	3	int:GBP3
Interaction	SNW1 interactions	HSP90B1 ESS2 PSMD2 PSMD3 NCAPH TTK SMC3 SF3A3 DIAPH3 EXOC7 GCN1 TOP1 PML RAD21	1.32e-05	747	97	14	int:SNW1
Interaction	TERF2IP interactions	SETX ESS2 SRCAP NXNL1 TAF9B SUPT6H SF3A3 HTATSF1 TAF1 TOP1 PML RAD21	1.36e-05	552	97	12	int:TERF2IP
Interaction	CDC5L interactions	STK36 HSP90B1 SETX ESS2 PSMD2 PSMD3 NCAPH SMC3 YLPM1 SF3A3 KIF3C EXOC7 GCN1 TOP1 PML	1.38e-05	855	97	15	int:CDC5L
Interaction	YAP1 interactions	JCAD HSP90B1 ESS2 ANK3 PSMD2 SRCAP NCAPH THBS1 TAF3 TAF9B ZPR1 RAB3GAP2 YLPM1 TAF1 GCN1 SNX1 PML	1.70e-05	1095	97	17	int:YAP1
Interaction	KCNA3 interactions	HSP90B1 ANK3 DSC2 ZFYVE16 PSMD2 PSMD3 TTK SMC3 RAB3GAP2 TCF25 DIAPH3 ALDH3A2 GCN1 TOP1 ARHGAP21	1.72e-05	871	97	15	int:KCNA3
Interaction	ATG16L1 interactions	HSP90B1 ANK3 LEMD3 TNPO2 CNTRL PSMD2 ZCCHC17 TTK ITPR1 SMC3 YLPM1 SYK PLCG2 DIAPH3 SNAPC4 GCN1 TOP1	3.58e-05	1161	97	17	int:ATG16L1
Interaction	RNF43 interactions	HSP90B1 MIA3 ANK3 ZFYVE16 LEMD3 PSMD2 TTK ALDH3A2 GCN1 ARHGAP21	3.99e-05	427	97	10	int:RNF43
Interaction	VCP interactions	ANKRD13D HSP90B1 ESS2 TNPO2 PSMD2 PSMD3 NCAPH TTK C2CD5 ITPR1 SUPT6H RAB3GAP2 OS9 PRKCZ DIAPH3 ALDH3A2 PGM2 TOP1 PML	4.64e-05	1435	97	19	int:VCP
Interaction	CIT interactions	NES HSP90B1 SETX MYO9B TNPO2 HCN1 ASH1L PSMD2 ADGRV1 DNAH12 TAF9B SMC3 SUPT6H SF3A3 TCF25 GCN1 PGM2 TOP1 RAD21	5.34e-05	1450	97	19	int:CIT
Interaction	CALR3 interactions	TOR1AIP2 HSP90B1 MIA3 ADGRV1 SIL1 OS9	6.43e-05	142	97	6	int:CALR3
Interaction	FEZ2 interactions	KIF3B SMC3 KIF3C PRKCZ	6.46e-05	45	97	4	int:FEZ2
Interaction	AURKB interactions	HSP90B1 MIA3 SETX CNTRL PSMD2 PSMD3 ADGRV1 NCAPH TTK PHKB TAF1 SNAPC4 GCN1	7.17e-05	761	97	13	int:AURKB
Interaction	FEZ1 interactions	ANK3 SMC3 RAB3GAP2 HTATSF1 PRKCZ	7.40e-05	90	97	5	int:FEZ1
Interaction	SPATA25 interactions	TAF3 TAF9B TAF1	8.37e-05	18	97	3	int:SPATA25
Interaction	B3GAT1 interactions	TOR1AIP2 MIA3 DSC2 ZFYVE16 LEMD3 TNPO2 ITPR1 RAB3GAP2 ALDH3A2	8.56e-05	377	97	9	int:B3GAT1
Interaction	PDIA4 interactions	TOR1AIP2 HSP90B1 MIA3 CNTRL SIL1 SUPT6H OS9 PRKCZ CDH2 ARHGAP21	8.58e-05	468	97	10	int:PDIA4
Interaction	H3C1 interactions	ANK3 LEMD3 ASH1L PSMD3 SRCAP THBS1 TAF3 PIEZO2 SMC3 DPF3 TAF1 CABIN1 TOP1 RAD21	1.02e-04	901	97	14	int:H3C1
Interaction	SENP3 interactions	HSP90B1 SETX MYO9B PSMD2 NCAPH TCF25 TAF1 PML	1.03e-04	301	97	8	int:SENP3
Interaction	TRRAP interactions	JCAD STK36 HSP90B1 CNTRL GBP2 PSMD3 SRCAP ITPR1 TAF9B SMC3 HTATSF1 PLCG2 ARHGAP21	1.04e-04	790	97	13	int:TRRAP
Interaction	POU5F1 interactions	LEMD3 PSMD2 PSMD3 SMC3 SF3A3 TAF1 CABIN1 GCN1 TOP1 PML RAD21	1.15e-04	584	97	11	int:POU5F1
Interaction	ERBB2 interactions	HSP90B1 MIA3 PSMD3 ITPR1 SUPT6H SYK PLCG2 ALDH3A2 CDH2 TOP1 EPHB1	1.24e-04	589	97	11	int:ERBB2
Interaction	GBP2 interactions	GBP7 GBP1 GBP2 GBP3	1.33e-04	54	97	4	int:GBP2
Interaction	RAB9A interactions	TOR1AIP2 MIA3 DSC2 ZFYVE16 LEMD3 CNTRL SMC3 WASHC5 RAB3GAP2 ALDH3A2 SNX1	1.35e-04	595	97	11	int:RAB9A
Interaction	RMDN3 interactions	TOR1AIP2 HSP90B1 MIA3 LEMD3 TTK FNDC11 DIAPH3 ALDH3A2	1.41e-04	315	97	8	int:RMDN3
Interaction	ZCCHC10 interactions	MYO9B ZCCHC17 C2CD5 TAF3 TAF9B TAF1 CABIN1	1.45e-04	236	97	7	int:ZCCHC10
Interaction	TAF1L interactions	TAF9B TAF1 TAF1L	1.56e-04	22	97	3	int:TAF1L
Interaction	ERGIC2 interactions	TOR1AIP2 MIA3 LEMD3 SIL1 RAB3GAP2 STARD3NL ALDH3A2	1.57e-04	239	97	7	int:ERGIC2
Interaction	HSF1 interactions	HSP90B1 SETX PSMD2 NCAPH SUPT6H ZPR1 SF3A3 TAF1 TOP1 SNX1 PML	1.66e-04	609	97	11	int:HSF1
Interaction	RAC3 interactions	DSC2 ZFYVE16 LEMD3 TNFRSF21 C2CD5 ITPR1 SYNJ2 DIAPH3 ALDH3A2 CDH2 ARHGAP21	1.91e-04	619	97	11	int:RAC3
Interaction	MCM2 interactions	HSP90B1 ANK3 MYO9B PSMD2 PSMD3 C2CD5 TAF3 TCHH SMC3 CABIN1 GCN1 TOP1 SNX1 PML RAD21	1.97e-04	1081	97	15	int:MCM2
Interaction	KIF3B interactions	KIF3B KIF3C CDH2 RAD21	2.00e-04	60	97	4	int:KIF3B
Interaction	KIFAP3 interactions	KIF3B SMC3 KIF3C TAF1 CDH2	2.08e-04	112	97	5	int:KIFAP3
Interaction	SIRT6 interactions	MIA3 LEMD3 PSMD2 SRCAP C2CD5 ITPR1 SMC3 SUPT6H YLPM1 PML RAD21	2.16e-04	628	97	11	int:SIRT6
Interaction	TBP interactions	TCF12 NCAPH TAF3 TAF9B TAF1 SNAPC4 TAF1L	2.22e-04	253	97	7	int:TBP
Interaction	PSMD14 interactions	BCL2L14 HSP90B1 SETX CNTRL PSMD2 PSMD3 SUPT6H SF3A3 TOP1 PML	2.25e-04	527	97	10	int:PSMD14
Interaction	FGFR1 interactions	MIA3 ANK3 ZFYVE16 LEMD3 TTK WASHC5 RAB3GAP2 PLCG2 ALDH3A2 CDH2 SNX1	2.28e-04	632	97	11	int:FGFR1
Interaction	HDAC5 interactions	HSP90B1 PSMD2 PSMD3 SIK3 THBS1 SMC3 SUPT6H GCN1 TOP1	2.38e-04	432	97	9	int:HDAC5
Interaction	NUP50 interactions	ESS2 LEMD3 NCAPH TAF3 SUPT6H HTATSF1 TAF1 PML	2.42e-04	341	97	8	int:NUP50
Interaction	H3-3A interactions	ESS2 ASH1L SRCAP TAF3 SMC3 DPF3 TAF1 SNAPC4 CABIN1 TOP1 PML RAD21	2.51e-04	749	97	12	int:H3-3A
Interaction	SUZ12 interactions	SETX TNPO2 NCAPH TAF3 SMC3 SF3A3 HTATSF1 GCN1 TOP1 PML RAD21	2.68e-04	644	97	11	int:SUZ12
Interaction	TNFSF13B interactions	TNPO2 NCAPH ALDH3A2 EXOC7 GCN1	2.76e-04	119	97	5	int:TNFSF13B
Interaction	BRCA1 interactions	HSP90B1 SETX PSMD2 PSMD3 ITPR1 SMC3 SUPT6H SF3A3 OS9 DCLRE1A CABIN1 GCN1 TOP1 ARHGAP21 PML RAD21	2.92e-04	1249	97	16	int:BRCA1
Interaction	SEC61B interactions	TOR1AIP2 HSP90B1 MIA3 DSC2 LEMD3 SIL1 ITPR1 RAB3GAP2 HTATSF1 PRKCZ ALDH3A2 CDH2	2.97e-04	763	97	12	int:SEC61B
Interaction	TAF7L interactions	TAF3 TAF9B TAF1	3.24e-04	28	97	3	int:TAF7L
Interaction	NDN interactions	HSP90B1 ZCCHC17 NCAPH SMC3 ALDH3A2 CDH2 GCN1 CDH4 TOP1	3.37e-04	453	97	9	int:NDN
Interaction	OBSL1 interactions	NES HSP90B1 PSMD2 PSMD3 SRCAP PRDM11 SMC3 SUPT6H YLPM1 SF3A3 TCF25 GCN1 TOP1	3.81e-04	902	97	13	int:OBSL1
Interaction	SMARCA4 interactions	HSP90B1 SIK3 SRCAP SMC3 DPF3 RAB3GAP2 CABIN1 TOP1 PML	3.89e-04	462	97	9	int:SMARCA4
Interaction	AXL interactions	HSP90B1 MIA3 NCAPH SMC3 ALDH3A2 GCN1 SNX1 RAD21	4.10e-04	369	97	8	int:AXL
Interaction	PXMP2 interactions	TOR1AIP2 HSP90B1 MIA3 LEMD3 ITPR1 RAB3GAP2 ALDH3A2	4.19e-04	281	97	7	int:PXMP2
Interaction	SLX4 interactions	HSP90B1 TCF12 ESS2 SMC3 SUPT6H DCLRE1A GCN1 SNX1 PML RAD21	4.31e-04	572	97	10	int:SLX4
Interaction	DNAJC25 interactions	TOR1AIP2 MIA3 LEMD3 ITPR1 RAB3GAP2 OS9 ALDH3A2	4.47e-04	284	97	7	int:DNAJC25
Cytoband	1p22.2	GBP7 GBP1 GBP2 GBP3	3.69e-07	28	97	4	1p22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr1p22	GBP7 GBP1 GBP2 GBP3	2.12e-04	137	97	4	chr1p22
Cytoband	12p12.1	C2CD5 SPX	1.73e-03	29	97	2	12p12.1
GeneFamily	CD molecules\|Type I classical cadherins	CDH2 CDH4	1.04e-04	5	59	2	1185
GeneFamily	Cohesin complex	SMC3 RAD21	2.89e-04	8	59	2	1060
Coexpression	GSE22432_MULTIPOTENT_PROGENITOR_VS_CDC_UP	DSC2 GBP7 ADGRV1 PIEZO2 DDHD1 OS9 PML	9.44e-06	199	97	7	M7817
Coexpression	GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP	TCF12 ANK3 DPF3 DDHD1 TCF25 KIF3C TOP1	9.75e-06	200	97	7	M5122
Coexpression	ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_OVERLAP_UP	GBP7 GBP1 GBP2 GBP3 AIF1	3.24e-05	98	97	5	MM460
Coexpression	ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_UP	GBP7 GBP1 GBP2 GBP3 AIF1	3.57e-05	100	97	5	MM458
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	ZFYVE16 CNTRL ITPR1 TCF25 SNAPC4 CABIN1	3.62e-05	166	97	6	M6826
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_ADC_2_CELL	UAP1 GBP1 GBP2 GBP3 TCHH	4.11e-05	103	97	5	M45742
Coexpression	ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP	GBP7 GBP1 GBP2 GBP3 AIF1 DCLRE1A	5.02e-05	176	97	6	MM1048
Coexpression	RUAN_RESPONSE_TO_TNF_UP	GBP1 GBP2 GBP3	6.23e-05	21	97	3	MM651
Coexpression	GREENBAUM_E2A_TARGETS_DN	GBP1 GBP2 GBP3	7.19e-05	22	97	3	MM635
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SETX TCF12 ZFYVE16 MYO9B SIK3 TTK C2CD5 ITPR1 SMC3 SYNJ2 CDH2 TOP1	7.62e-05	856	97	12	M4500
Coexpression	CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP	HSP90B1 ANK3 THBS1 HTATSF1 TOP1	8.86e-05	121	97	5	M12828
Coexpression	PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP	HSP90B1 PSMD2 PSMD3 SIL1	9.45e-05	64	97	4	M7488
Coexpression	GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN	CNTRL PHKB RAB3GAP2 SYK OS9 EPHB1	9.62e-05	198	97	6	M5001
Coexpression	GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN	GBP7 TTK C2CD5 ITPR1 SF3A3 DIAPH3	9.89e-05	199	97	6	M8109
Coexpression	HALLMARK_MITOTIC_SPINDLE	MYO9B CNTRL TTK KIF3B SMC3 KIF3C	9.89e-05	199	97	6	M5893
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	TCF12 GBP2 SIK3 C2CD5 KIF3B TOP1	9.89e-05	199	97	6	M1746
Coexpression	GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN	ANK3 GBP1 GBP2 ITPR1 THBS1 PRKCZ	1.02e-04	200	97	6	M4632
Coexpression	GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP	BCL2L14 TCF12 WASHC5 AIF1 STARD3NL TOP1	1.02e-04	200	97	6	M7148
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_DN	TOR1AIP2 HSP90B1 TTK KIF3B SMC3 TCF25	1.02e-04	200	97	6	M3963
Coexpression	ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	TCF12 GBP2 SIK3 C2CD5 KIF3B TOP1	1.02e-04	200	97	6	MM1033
Coexpression	RUAN_RESPONSE_TO_TNF_TROGLITAZONE_UP	GBP1 GBP2 GBP3	1.07e-04	25	97	3	MM672
Coexpression	CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP	HSP90B1 ANK3 THBS1 HTATSF1 TOP1	1.34e-04	132	97	5	MM465
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	ANK3 TNPO2 ASH1L GBP1 SRCAP SIL1 SPX FNDC11 TCF25 SNAPC4 EXOC7 CDH4	1.34e-04	909	97	12	M41018
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	HSP90B1 SETX TTK ITPR1 PIEZO2 SMC3 WASHC5 HTATSF1 DIAPH3 RAD21	1.60e-04	656	97	10	M18979
Coexpression	CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP	NES UAP1 NCAPH TTK KIF3C	2.07e-04	145	97	5	M3045
Coexpression	HOWARD_MONOCYTE_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP	GBP1 GBP2 GBP3 ADGRV1 PRDM11 PML	2.22e-04	231	97	6	M40995
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NES GBP7 CNTRL ASH1L GBP2 GBP3 SMC3	1.28e-07	178	97	7	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	BCL2L14 ANK3 GBP1 GBP2 GBP3 TOP1 PML	1.33e-07	179	97	7	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	BCL2L14 ANK3 GBP1 GBP2 GBP3 TOP1 PML	1.86e-07	188	97	7	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	ASH1L GBP1 GBP2 GBP3 THBS1 PML	3.03e-06	183	97	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANK3 ZFYVE16 SIK3 PIEZO2 SYNJ2 ARHGAP21	4.24e-06	194	97	6	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	Control-PLT_4\|Control / Disease Group and Platelet Clusters	SETX LEMD3 DNAH12 SMC3 DPF3 TOP1	4.77e-06	198	97	6	387fd3037fd52e4d4c42de0588767e58af228b59
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1-28\|World / Primary Cells by Cluster	HSP90B1 CNTRL NCAPH TTK DIAPH3 RAD21	4.91e-06	199	97	6	787688b68ae5d8768c0a24673ae07ab07616764a
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1\|World / Primary Cells by Cluster	HSP90B1 CNTRL NCAPH TTK DIAPH3 RAD21	4.91e-06	199	97	6	72823f26ecabcae1b514b7629cfce010c97b929a
ToppCell	COVID\|World / Condition, Cell_class and T cell subcluster	CCDC170 DSC2 DBNDD2 SYK AIF1 ARHGAP21	5.05e-06	200	97	6	04a932fe2431e7886120c219ce666f90d3030a1c
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES CNTRL ITPR1 PRDM11 TAF9B	2.41e-05	157	97	5	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GBP3 TNFRSF21 THBS1 AIF1 SNX1	2.98e-05	164	97	5	f88871d3b9307112eb7ced4c629f5704326ecae8
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CALHM2 SPX THBS1 PLCG2 CDH2	3.06e-05	165	97	5	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GBP1 APOBEC2 SYK PRKCZ PML	3.25e-05	167	97	5	3c3e1c31aacca48099693aea2efdfa22fc0e4af4
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Zbtb32+_B_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GBP1 APOBEC2 SYK PRKCZ PML	3.25e-05	167	97	5	77a4d7ce44847c76074d4f5340d61b398fe43e6c
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CALHM2 SPX THBS1 PLCG2 CDH2	3.34e-05	168	97	5	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF21 THBS1 SYK AIF1 PLCG2	3.34e-05	168	97	5	0ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFRSF21 THBS1 SYK AIF1 PLCG2	3.34e-05	168	97	5	ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOBEC2 SYK RASSF3 PLCG2 PML	3.95e-05	174	97	5	2f4bc0275cbcaa830d04a4c76e042456908d2277
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOBEC2 SYK RASSF3 PLCG2 PML	3.95e-05	174	97	5	01eff218e71a04201189a0313aaf91437fffed95
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOBEC2 SYK RASSF3 PLCG2 PML	3.95e-05	174	97	5	f0f6d135e1fb4c15022be103b00d8d5456515a18
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTK SPX DIAPH3 CDH2 RAD21	4.28e-05	177	97	5	2b63f0529ef73e0eede9b7ef1f08b0a0426a9c82
ToppCell	CD8+_Memory_T_cell-RSV-2\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	NCAPH TTK SDHAF3 DIAPH3 PGM2	4.89e-05	182	97	5	f5f17a80552f0ad05ed1a2529a04ee55deb1e130
ToppCell	B_cells-ABCs\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	BCL2L14 DSC2 GBP1 GBP2 PML	5.02e-05	183	97	5	bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NCAPH TTK DIAPH3 CDH2 CDH4	5.28e-05	185	97	5	282b3de8850f3c21704339e8d8737b432a43441a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(15)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HSP90B1 NCAPH TTK DIAPH3 RAD21	5.28e-05	185	97	5	6aeae77a087d695b1e58c5f63265e7113aa2e343
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-plasmacytoid_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TNFRSF21 SPX ITPR1 DCLRE1A EPHB1	5.56e-05	187	97	5	d3563bb087e476baea5b59389e4d34d0ff98cac5
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES NCAPH TTK DIAPH3 RAD21	5.70e-05	188	97	5	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	Control\|World / Disease state, Lineage and Cell class	ZFYVE16 MYO9B SIK3 THBS1 SUPT6H	5.85e-05	189	97	5	fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTRL NCAPH TTK DIAPH3 RAD21	5.99e-05	190	97	5	cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCell	wk_20-22-Hematologic-Myeloid-Cycling_DC\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DBNDD2 NCAPH TTK AIF1 DIAPH3	6.15e-05	191	97	5	1da569ebcfab4e1a95315430ae77a17a1f119263
ToppCell	NS-moderate-d_0-4-Lymphoid\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NCAPH TTK SASH3 APOBEC2 DIAPH3	6.30e-05	192	97	5	905217dcfc843d3469e9e71bd33707863b14cc82
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NES NCAPH TTK DIAPH3 RAD21	6.46e-05	193	97	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	Leuk-UTI\|World / Disease, Lineage and Cell Type	GBP7 GBP1 GBP2 GBP3 AIF1	6.46e-05	193	97	5	26119a0b5d7684022fd16b8b73a0ef5a7d70f3d1
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADGRV1 NCAPH TTK SYK DIAPH3	6.61e-05	194	97	5	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZFYVE16 MYO9B TNFRSF21 DDHD1 SYK	6.78e-05	195	97	5	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	BCL2L14 GBP1 GBP2 GBP3 PML	6.78e-05	195	97	5	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CNTRL NCAPH TTK DIAPH3 RAD21	6.78e-05	195	97	5	742c82c86487314cdb3178012004adb1164bcbdb
ToppCell	severe-Plasmablast\|severe / disease stage, cell group and cell class	HSP90B1 UAP1 SIL1 OS9 TOP1	6.78e-05	195	97	5	e11616ad568e50e4c720b50b0c071f484c31d16b
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANK3 SIK3 PIEZO2 SYNJ2 ARHGAP21	7.11e-05	197	97	5	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	(5)_Dendritic_cell-(53)_Lymphoid_DC\|(5)_Dendritic_cell / shred on Cell_type and subtype	BCL2L14 DBNDD2 TCHH PIEZO2 ARHGAP21	7.28e-05	198	97	5	548da5fa86f9756c503ed77bcdde55bc4d1a2726
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ADGRV1 TNFRSF21 THBS1 CDH4 EPHB1	7.28e-05	198	97	5	90ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCell	PBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HSP90B1 UAP1 NCAPH TTK DIAPH3	7.28e-05	198	97	5	2d8d4eb21b4fe3cc178b3518b3ea39c2d9650f24
ToppCell	BAL-Severe\|BAL / Compartment, Disease Groups and Clusters	BCL2L14 GBP1 GBP2 TOP1 PML	7.28e-05	198	97	5	f63cfcc57f46094ea0673bbc70ea443ebaca6176
ToppCell	mLN-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	NCAPH TTK DPF3 SYK DIAPH3	7.46e-05	199	97	5	c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GBP1 GBP2 GBP3 SASH3 RASSF3	7.46e-05	199	97	5	841338719d042247966867ac608146395eb8c4d9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SRCAP ITPR1 THBS1 SASH3 SYK	7.46e-05	199	97	5	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CNTRL NCAPH TTK DIAPH3 RAD21	7.46e-05	199	97	5	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CNTRL NCAPH TTK DIAPH3 RAD21	7.64e-05	200	97	5	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	CNTRL NCAPH TTK DIAPH3 RAD21	7.64e-05	200	97	5	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	(2)_B_cell-(20)_B_cell_IgA_Plasma\|(2)_B_cell / shred on Cell_type and subtype	HSP90B1 UAP1 PSMD2 SIL1 OS9	7.64e-05	200	97	5	42afce995f9a7de0406cc836e1f09b3f168a066c
ToppCell	severe_influenza\|World / disease group, cell group and cell class (v2)	DSC2 GBP1 THBS1 SYK AIF1	7.64e-05	200	97	5	2c965ec0c33a797c227a06dac90b5ecb959816f6
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SETX ASH1L GBP1 TCF25 PLCG2	7.64e-05	200	97	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Severe-Developping_Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HSP90B1 UAP1 NCAPH TTK DIAPH3	7.64e-05	200	97	5	80639e0d2ddaae36ac7634a4f03e8809af7316e3
ToppCell	(21)_B_cell_IgG_Plasma\|World / shred on Cell_type and subtype	HSP90B1 UAP1 PSMD2 SIL1 OS9	8.19e-05	203	97	5	15055e1b1017afbdb2a567972cbb976deb7d4e6a
ToppCell	(20)_B_cell_IgA_Plasma\|World / shred on Cell_type and subtype	HSP90B1 UAP1 PSMD2 SIL1 OS9	8.38e-05	204	97	5	fcca2135876031644a81d4aa3bc04145558f7745
ToppCell	(53)_Lymphoid_DC\|World / shred on Cell_type and subtype	BCL2L14 DSC2 DBNDD2 PIEZO2 ARHGAP21	9.18e-05	208	97	5	30212cfacad94a7cc562a69efa73a31259851515
ToppCell	Endothelial-Endothelial-H_(cycle)\|Endothelial / shred on cell class and cell subclass (v4)	DSC2 CAV3 DIAPH3 RAD21	2.35e-04	138	97	4	a1f41a5a9da40adcc343722baef78c603599c3f0
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Gad1Gad2_Id2.Tac1_(Interneuron,_Neurogliaform1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DSC2 CAV3 PIEZO2	2.48e-04	56	97	3	c1bdee477c871c03d60feed26b24d9f3d4171cb6
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Gad1Gad2_Id2.Tac1_(Interneuron,_Neurogliaform1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	DSC2 CAV3 PIEZO2	2.48e-04	56	97	3	c78cbec68922b382595758e100dda9d284836c25
ToppCell	LPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES GBP3 PLCG2 DIAPH3	2.62e-04	142	97	4	b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 PIEZO2 ZPR1 AIF1	2.77e-04	144	97	4	cf9f049ab6cd80521598124f057c2debdde24788
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 PIEZO2 ZPR1 AIF1	2.77e-04	144	97	4	41eaeca54b3c39de417597267cbdb1f195dd885a
ToppCell	343B-Myeloid-Dendritic-cDC1\|343B / Donor, Lineage, Cell class and subclass (all cells)	BCL2L14 AIF1 CDH2 EPHB1	3.07e-04	148	97	4	e44cdc1c3f3314c549a0afa9298c8568022b9d8b
ToppCell	E16.5-samps-Myeloid-Fetal_macrophage-macrophage_-_intermediate_-_unactivated\|E16.5-samps / Age Group, Lineage, Cell class and subclass	GBP3 NXNL1 SASH3 AIF1	3.23e-04	150	97	4	60fdd266aaca1b589b9a77465a4a7fad4921339a
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ESS2 NCAPH THBS1 CDH2	3.66e-04	155	97	4	4559e3011514041b65c17ae4ede29da202bce14c
ToppCell	PND03-Immune-Immune_Myeloid-DC-maDC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UAP1 GBP2 AIF1 CDH2	3.75e-04	156	97	4	095281ea78aefa0ee638191a03f8d6f62a86a9ff
ToppCell	facs-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF21 WASHC5 SYK AIF1	3.75e-04	156	97	4	3f0b9e35d4da85c90759b930052e5b9c3cde9b15
ToppCell	facs-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF21 WASHC5 SYK AIF1	3.75e-04	156	97	4	69e6e8810d1738a66c9821910f41498931cf30cc
ToppCell	PND03-Immune-Immune_Myeloid-DC-maDC-maDC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UAP1 GBP2 AIF1 CDH2	3.75e-04	156	97	4	29b04143f71a0ecc600ac670abd1d521bee55fe7
ToppCell	E16.5-samps-Myeloid\|E16.5-samps / Age Group, Lineage, Cell class and subclass	GBP3 SASH3 AIF1 PLCG2	3.75e-04	156	97	4	c7c73cef5700b0ae75280e62c94728434c712537
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESS2 SIK3 PRKCZ PML	3.84e-04	157	97	4	a426c54fd1545093d41426e9620862f71bd06f6b
ToppCell	Control-Lymphocyte-T_NK-dnT\|Control / Disease, Lineage and Cell Type	UAP1 GBP2 SPX FNDC11	3.94e-04	158	97	4	7a2fad6426549d910834debfe5e102fe2ab5976d
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESS2 TAF9B DCLRE1A DIAPH3	3.94e-04	158	97	4	ee8ce3cd202807df692b28bb1a81827d49d73862
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13D TNFRSF21 SYK PLCG2	3.94e-04	158	97	4	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13D TNFRSF21 SYK PLCG2	3.94e-04	158	97	4	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	Leuk-UTI-Myeloid-tDC\|Leuk-UTI / Disease, Lineage and Cell Type	TOR1AIP2 TTK TNFRSF21 EPHB1	4.23e-04	161	97	4	51b9f60986ed2e8e2297d31c80462c3ab65a2e5e
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GBP7 GBP3 SASH3 AIF1	4.23e-04	161	97	4	5a8698790f9aba796dd2b64af419055c60bd7de8
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SASH3 SYK AIF1 PLCG2	4.23e-04	161	97	4	16f77e7a5444d2f2b210362816cd7a07b9b42af6
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SASH3 SYK AIF1 PLCG2	4.23e-04	161	97	4	f5821f551cf5c64c9f75cdb723492c87aac1ece0
ToppCell	facs-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SASH3 SYK AIF1 PLCG2	4.23e-04	161	97	4	58a32a1033f379579697bda1bbf047a088e4a34f
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	ANK3 ASH1L ITPR1 DDHD1	4.32e-04	162	97	4	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	facs-MAT-Fat-3m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL2L14 SYK AIF1 PLCG2	4.53e-04	164	97	4	b81498c3934e0d52bf0329dc745e02966f9d8613
ToppCell	droplet-Lung-nan-18m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF21 THBS1 AIF1 PLCG2	4.63e-04	165	97	4	e32697321cef424c2ad4e11ee9da3e510d5ce505
ToppCell	droplet-Lung-nan-18m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF21 THBS1 AIF1 PLCG2	4.63e-04	165	97	4	0fbdd043e11aa8dbff4cd3a4da1b2feb49878a09
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBP1 TNFRSF21 DDHD1 AIF1	4.74e-04	166	97	4	03a47b8687f54955e84df1edcb230db332c4ca8f
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SPX THBS1 PLCG2 CDH2	4.74e-04	166	97	4	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SETX ZPR1 SYK GCN1	4.85e-04	167	97	4	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPR1 SASH3 SYK PLCG2	4.96e-04	168	97	4	eeb381b62c7ba263af96de1194ed59e57b6ca3ae
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B-B_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPR1 SASH3 SYK PLCG2	4.96e-04	168	97	4	063d0368d656962b335154c230bdcd9236e7c9ad
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	UAP1 FRMPD1 GBP1 NXNL1	4.96e-04	168	97	4	74d6dbf9295933acdee785af9b73a94377d15412
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITPR1 SASH3 SYK PLCG2	4.96e-04	168	97	4	a7c4251d8a83bc30196a444028a35c17c24dc291
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF21 THBS1 SYK PLCG2	5.07e-04	169	97	4	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF21 THBS1 SYK PLCG2	5.07e-04	169	97	4	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	droplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOBEC2 SYK RASSF3 PLCG2	5.19e-04	170	97	4	29deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCell	droplet-Thymus-nan-21m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOBEC2 SYK RASSF3 PLCG2	5.19e-04	170	97	4	dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TNPO2 TTK C2CD5 RAD21	5.19e-04	170	97	4	a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	BCL2L14 PIEZO2 CDH2 ARHGAP21	5.19e-04	170	97	4	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NES NWD2 SYNJ2 CDH2	5.19e-04	170	97	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MIA3 GBP1 GBP3 PML	5.19e-04	170	97	4	07b561cd9c528bc8444c9385e1de621eee7b697e
ToppCell	droplet-Thymus-nan-21m-Myeloid-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APOBEC2 SYK RASSF3 PLCG2	5.30e-04	171	97	4	8bed33f61f7d12a1ac4fba33f730d839f5ee7bef
Drug	staurosporine; Up 200; 0.01uM; MCF7; HG-U133A	TOR1AIP2 CAV3 TNFRSF21 THBS1 SUPT6H RAB3GAP2 YLPM1 RAD21	1.75e-06	193	97	8	425_UP
Drug	Cefotaxime sodium salt [64485-93-4]; Down 200; 8.4uM; PC3; HT_HG-U133A	GBP1 ITPR1 SUPT6H SYK HTATSF1 KIF3C ALDH3A2 PML	2.04e-06	197	97	8	2072_DN
Drug	forskolin; Up 200; 50uM; MCF7; HT_HG-U133A_EA	CNTRL GBP2 SRCAP ITPR1 THBS1 YLPM1 TCF25	4.95e-06	157	97	7	913_UP
Drug	6-chloro-6-deoxymannose	GBP7 GBP1 GBP2	6.18e-06	9	97	3	CID000021090
Drug	trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	TNPO2 FRMPD1 SRCAP ITPR1 KIF3C EXOC7 PML	1.35e-05	183	97	7	5221_UP
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; PC3; HT_HG-U133A	TNPO2 CNTRL TNFRSF21 THBS1 APOBEC2 HTATSF1 SNAPC4	1.50e-05	186	97	7	3819_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	HSP90B1 SMC3 SYNJ2 YLPM1 TCF25 HTATSF1 RAD21	1.55e-05	187	97	7	4302_DN
Drug	Piromidic acid [19562-30-2]; Down 200; 13.8uM; HL60; HT_HG-U133A	ANK3 ZFYVE16 FRMPD1 SIL1 SYNJ2 TAF1 EXOC7	1.90e-05	193	97	7	2996_DN
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; HL60; HG-U133A	ESS2 MYO9B KIF3B YLPM1 HTATSF1 OS9 ALDH3A2	1.90e-05	193	97	7	1363_DN
Drug	Moxalactam disodium salt [64953-12-4]; Down 200; 7uM; PC3; HT_HG-U133A	JCAD DSC2 TNFRSF21 ITPR1 THBS1 PLCG2 CDH2	1.97e-05	194	97	7	4648_DN
Drug	Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; MCF7; HT_HG-U133A	SETX SRCAP THBS1 KIF3C SNAPC4 EXOC7 PML	2.03e-05	195	97	7	7435_UP
Drug	Oxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	SETX SRCAP ITPR1 SMC3 SNAPC4 EXOC7 CABIN1	2.10e-05	196	97	7	2103_DN
Drug	Gemfibrozil [25812-30-0]; Down 200; 16uM; PC3; HT_HG-U133A	HSP90B1 DSC2 ITPR1 PHKB YLPM1 DCLRE1A ALDH3A2	2.10e-05	196	97	7	2113_DN
Drug	Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; HL60; HG-U133A	BCL2L14 PSMD3 SPX SASH3 SDHAF3 YLPM1 SNAPC4	2.10e-05	196	97	7	1593_DN
Drug	Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; PC3; HT_HG-U133A	JCAD ESS2 SUPT6H YLPM1 DCLRE1A KIF3C EXOC7	2.10e-05	196	97	7	7123_DN
Drug	fludrocortisone acetate; Up 200; 1uM; MCF7; HG-U133A	LEMD3 TNPO2 THBS1 PIEZO2 SYNJ2 SUPT6H RAB3GAP2	2.17e-05	197	97	7	281_UP
Drug	Norfloxacin [70458-96-7]; Down 200; 12.6uM; HL60; HG-U133A	TNPO2 GBP2 TNFRSF21 SPX SYK TAF1 PML	2.17e-05	197	97	7	1406_DN
Drug	iloprost; Up 200; 1uM; MCF7; HG-U133A	TOR1AIP2 SIK3 PIEZO2 SUPT6H RAB3GAP2 YLPM1 CABIN1	2.24e-05	198	97	7	427_UP
Drug	Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; HL60; HG-U133A	BCL2L14 CNTRL ASH1L CALHM2 SASH3 OS9 CABIN1	2.24e-05	198	97	7	1596_DN
Drug	Levopropoxyphene napsylate [5714-90-9]; Up 200; 7.4uM; MCF7; HT_HG-U133A	MIA3 CNTRL ITPR1 SUPT6H APOBEC2 TAF1 PML	2.24e-05	198	97	7	5503_UP
Drug	0225151-0000 [351320-15-5]; Down 200; 10uM; PC3; HT_HG-U133A	DSC2 SRCAP THBS1 SYNJ2 DPF3 TAF1 SNAPC4	2.24e-05	198	97	7	6426_DN
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	DSC2 GBP2 ITPR1 SYK TAF1 CABIN1 PML	2.32e-05	199	97	7	988_UP
Drug	lurtotecan	STK36 ESS2 TOP1	3.29e-05	15	97	3	CID000060955
Drug	Mfpa	TAF1 TAF1L	5.37e-05	3	97	2	CID003035615
Drug	Succimer	HSP90B1 MIA3 TCF12 ANK3 DSC2 ZFYVE16 LEMD3 ASH1L GBP1 SIK3 ITPR1 THBS1 PIEZO2 SASH3 DDHD1 KIF3C	8.32e-05	1264	97	16	ctd:D004113
Drug	trifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A	MIA3 ESS2 ITPR1 RAB3GAP2 PML EPHB1	1.22e-04	180	97	6	5584_UP
Drug	Magnetite Nanoparticles	HSP90B1 MIA3 TCF12 ANK3 DSC2 ZFYVE16 LEMD3 ASH1L GBP1 SIK3 ITPR1 THBS1 PIEZO2 SASH3 DDHD1 KIF3C	1.26e-04	1310	97	16	ctd:D058185
Drug	LY 294002; Up 200; 10uM; MCF7; HT_HG-U133A	MIA3 CALHM2 ITPR1 SYK PML EPHB1	1.34e-04	183	97	6	5599_UP
Drug	geldanamycin; Up 200; 1uM; MCF7; HT_HG-U133A	HSP90B1 SETX GBP2 YLPM1 KIF3C PRKCZ	1.34e-04	183	97	6	6946_UP
Drug	NSC618487	STK36 PSMD2 TTK TNFRSF21 ITPR1 SYK TCF25 PRKCZ PLCG2 CABIN1 CDH2 TOP1 EPHB1	1.63e-04	933	97	13	CID000005279
Drug	Lanatoside C [17575-22-3]; Down 200; 4uM; HL60; HT_HG-U133A	TNFRSF21 CALHM2 SYNJ2 SYK DCLRE1A EXOC7	1.64e-04	190	97	6	2193_DN
Drug	Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; PC3; HT_HG-U133A	TOR1AIP2 DSC2 SIK3 SYNJ2 YLPM1 TCF25	1.69e-04	191	97	6	4273_DN
Drug	Danazol [17230-88-5]; Down 200; 11.8uM; HL60; HG-U133A	SETX NCAPH TNFRSF21 SNAPC4 CABIN1 SNX1	1.69e-04	191	97	6	2038_DN
Drug	vinblastine sulfate; Up 200; 0.1uM; PC3; HT_HG-U133A	JCAD SRCAP YLPM1 SYK SNAPC4 CABIN1	1.74e-04	192	97	6	7556_UP
Drug	Astemizole [68844-77-9]; Down 200; 8.8uM; HL60; HG-U133A	SUPT6H YLPM1 SYK SNAPC4 ALDH3A2 CABIN1	1.74e-04	192	97	6	1365_DN
Drug	AR18	GBP7 GBP2	1.78e-04	5	97	2	CID000114011
Drug	Guanfacine hydrochloride [29110-48-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A	NES MYO9B SYNJ2 SUPT6H EXOC7 PML	1.79e-04	193	97	6	5256_DN
Drug	Pivampicillin [33817-20-8]; Down 200; 8.6uM; PC3; HT_HG-U133A	DSC2 GBP1 THBS1 CABIN1 SNX1 PML	1.79e-04	193	97	6	5046_DN
Drug	Omeprazole [73590-58-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A	CNTRL GBP2 ITPR1 THBS1 SYNJ2 PML	1.79e-04	193	97	6	2828_DN
Drug	AC1OAGKW	ITPR1 THBS1 SYNJ2 PRKCZ PLCG2 SNX1	1.79e-04	193	97	6	CID006857413
Drug	Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A	GBP2 SRCAP TNFRSF21 THBS1 SYNJ2 PML	1.84e-04	194	97	6	2284_DN
Drug	Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A	TOR1AIP2 DSC2 SMC3 SYNJ2 TCF25 SNAPC4	1.84e-04	194	97	6	4272_DN
Drug	Fusaric acid [536-69-6]; Down 200; 22.4uM; MCF7; HT_HG-U133A	ANK3 GBP2 HTATSF1 TAF1 CABIN1 PML	1.84e-04	194	97	6	4105_DN
Drug	Benzydamine hydrochloride [132-69-4]; Down 200; 11.6uM; HL60; HG-U133A	TOR1AIP2 ASH1L GBP2 KIF3B YLPM1 CABIN1	1.84e-04	194	97	6	1552_DN
Drug	Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A	MYO9B TNPO2 KIF3C PLCG2 EXOC7 CABIN1	1.84e-04	194	97	6	2789_UP
Drug	Chloropyramine hydrochloride [6170-42-9]; Down 200; 12.2uM; PC3; HT_HG-U133A	ANK3 TNPO2 ITPR1 SYK TAF1 ALDH3A2	1.84e-04	194	97	6	4589_DN
Drug	6-mercaptopurine monohydrate; Up 200; 100uM; MCF7; HG-U133A	FRMPD1 SRCAP TNFRSF21 PIEZO2 CDH2 EPHB1	1.84e-04	194	97	6	334_UP
Drug	diclofenac sodium; Down 200; 10uM; MCF7; HG-U133A	ANK3 CAV3 TNFRSF21 CALHM2 PRDM11 SYNJ2	1.89e-04	195	97	6	333_DN
Drug	Betulin [473-98-3]; Down 200; 9uM; MCF7; HT_HG-U133A	ANK3 TCHH APOBEC2 EXOC7 CABIN1 PML	1.89e-04	195	97	6	3513_DN
Drug	(S)-propranolol hydrochloride [4199-10-4]; Down 200; 13.6uM; MCF7; HT_HG-U133A	NES CNTRL GBP2 SRCAP KIF3C CABIN1	1.89e-04	195	97	6	3523_DN
Drug	Ursolic acid [77-52-1]; Down 200; 8.8uM; PC3; HT_HG-U133A	MYO9B NCAPH SUPT6H DCLRE1A EXOC7 CABIN1	1.89e-04	195	97	6	5825_DN
Drug	Amitryptiline hydrochloride [549-18-8]; Down 200; 12.8uM; PC3; HT_HG-U133A	SRCAP ITPR1 SUPT6H DCLRE1A SNAPC4 EXOC7	1.89e-04	195	97	6	1823_DN
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; PC3; HT_HG-U133A	SUPT6H DPF3 SYK EXOC7 CABIN1 PML	1.89e-04	195	97	6	5884_UP
Drug	Tamoxifen citrate [54965-24-1]; Down 200; 7uM; PC3; HT_HG-U133A	SETX ZFYVE16 GBP1 SYNJ2 EXOC7 PML	1.89e-04	195	97	6	2050_DN
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A	NES SIK3 CALHM2 THBS1 KIF3C EXOC7	1.89e-04	195	97	6	6971_DN
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	DBNDD2 SRCAP TCHH SYK SNX1 PML	1.89e-04	195	97	6	5241_DN
Drug	CP-320650-01 [172079-28-6]; Up 200; 10uM; PC3; HT_HG-U133A	SETX SRCAP ITPR1 SYNJ2 FNDC11 SNAPC4	1.89e-04	195	97	6	4557_UP
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	MYO9B SUPT6H SNAPC4 EXOC7 CABIN1 PML	1.89e-04	195	97	6	1144_DN
Drug	Clobetasol propionate [25122-46-7]; Down 200; 8.6uM; PC3; HT_HG-U133A	JCAD DSC2 SYNJ2 DPF3 SYK SNAPC4	1.94e-04	196	97	6	4497_DN
Drug	Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	MYO9B ASH1L GBP2 SUPT6H HTATSF1 CABIN1	1.94e-04	196	97	6	1708_DN
Drug	Panthenol (D) [81-13-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A	DSC2 ZFYVE16 MYO9B PLCG2 SNAPC4 EXOC7	1.94e-04	196	97	6	7455_DN
Drug	Chlorzoxazone [95-25-0]; Up 200; 23.6uM; MCF7; HT_HG-U133A	JCAD DSC2 SASH3 APOBEC2 CDH2 PML	1.94e-04	196	97	6	2263_UP
Drug	chlorpromazine hydrochloride; Down 200; 10uM; MCF7; HG-U133A	THBS1 PIEZO2 SUPT6H YLPM1 PRKCZ SNAPC4	1.94e-04	196	97	6	419_DN
Drug	Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; HL60; HT_HG-U133A	NES ANK3 SRCAP SIL1 YLPM1 PML	1.94e-04	196	97	6	2939_UP
Drug	Methionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A	HSP90B1 MIA3 MYO9B GBP2 ITPR1 TAF1	1.94e-04	196	97	6	4151_DN
Drug	Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SRCAP YLPM1 SYK SNAPC4 CABIN1 PML	1.94e-04	196	97	6	4752_DN
Drug	Mefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A	ZFYVE16 SRCAP ITPR1 DCLRE1A EXOC7 CABIN1	1.94e-04	196	97	6	1821_DN
Drug	Verapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; PC3; HG-U133A	TOR1AIP2 HSP90B1 ANK3 YLPM1 KIF3C RAD21	1.94e-04	196	97	6	1927_DN
Drug	Lumicolchicine gamma [6901-14-0]; Up 200; 10uM; HL60; HT_HG-U133A	TNPO2 THBS1 KIF3C PRKCZ SNAPC4 PML	1.94e-04	196	97	6	1317_UP
Drug	Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A	FRMPD1 PRDM11 SUPT6H HTATSF1 EXOC7 SNX1	1.94e-04	196	97	6	4808_UP
Drug	novobiocin sodium, USP; Down 200; 100uM; ssMCF7; HG-U133A	DBNDD2 NCAPH TNFRSF21 SIL1 SNAPC4 EXOC7	1.94e-04	196	97	6	499_DN
Drug	AH6809; Down 200; 1uM; PC3; HT_HG-U133A	HSP90B1 ANK3 DSC2 SYNJ2 DCLRE1A SNAPC4	1.94e-04	196	97	6	7049_DN
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HG-U133A	MYO9B SRCAP SUPT6H HTATSF1 CDH2 SNX1	1.94e-04	196	97	6	1912_UP
Drug	PF-00539745-00 [351321-33-0]; Up 200; 10uM; MCF7; HT_HG-U133A	ANK3 DSC2 ASH1L ALDH3A2 EXOC7 PML	2.00e-04	197	97	6	5974_UP
Drug	THIP Hydrochloride; Up 200; 22.6uM; PC3; HT_HG-U133A	CNTRL GBP1 SRCAP SNAPC4 CABIN1 PML	2.00e-04	197	97	6	7266_UP
Drug	Orphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A	DSC2 SRCAP APOBEC2 SYK SNAPC4 PML	2.00e-04	197	97	6	3801_DN
Drug	nordihydroguaiaretic acid; Up 200; 1uM; ssMCF7; HG-U133A	HSP90B1 CAV3 TNFRSF21 THBS1 SYNJ2 HTATSF1	2.00e-04	197	97	6	415_UP
Drug	Boldine [476-70-0]; Down 200; 12.2uM; HL60; HT_HG-U133A	THBS1 SYNJ2 APOBEC2 KIF3C ALDH3A2 PML	2.00e-04	197	97	6	2148_DN
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; PC3; HT_HG-U133A	MYO9B TNPO2 GBP1 SRCAP SUPT6H SYK	2.00e-04	197	97	6	4501_DN
Drug	Clindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; PC3; HT_HG-U133A	DSC2 MYO9B SUPT6H YLPM1 SNAPC4 EXOC7	2.00e-04	197	97	6	5815_DN
Drug	LY294002; Down 200; 0.1uM; MCF7; HG-U133A	DBNDD2 SRCAP TNFRSF21 C2CD5 SPX PLCG2	2.00e-04	197	97	6	424_DN
Drug	Gliclazide [21187-98-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A	MYO9B CALHM2 THBS1 SYNJ2 SUPT6H SNX1	2.00e-04	197	97	6	2870_DN
Drug	Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	SETX THBS1 RAB3GAP2 DCLRE1A TAF1 PML	2.00e-04	197	97	6	6758_DN
Drug	17-DMAG; Down 200; 0.1uM; HL60; HT_HG-U133A	ANK3 FRMPD1 GBP1 TNFRSF21 SYNJ2 PML	2.00e-04	197	97	6	2673_DN
Drug	copper(II) sulfate pentahydrate; Up 200; 100uM; MCF7; HG-U133A	CCDC170 JCAD HSP90B1 TNFRSF21 FNDC11 CDH2	2.00e-04	197	97	6	575_UP
Drug	Lorglumide sodium salt [97964-56-2]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ESS2 GBP1 TNFRSF21 CALHM2 KIF3C EXOC7	2.00e-04	197	97	6	6456_DN
Drug	sulindac; Down 200; 50uM; MCF7; HG-U133A	TNPO2 CAV3 PHKB PRDM11 PIEZO2 PML	2.05e-04	198	97	6	307_DN
Drug	GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A	TNFRSF21 DPF3 YLPM1 KIF3C CABIN1 PML	2.05e-04	198	97	6	6559_DN
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A	MYO9B SRCAP TCHH SYK DCLRE1A SNX1	2.05e-04	198	97	6	6464_DN
Drug	Cefepime hydrochloride [123171-59-5]; Down 200; 7.4uM; MCF7; HT_HG-U133A	DSC2 ITPR1 THBS1 YLPM1 TAF1 PML	2.05e-04	198	97	6	3581_DN
Drug	Fipexide hydrochloride [34161-23-4]; Down 200; 9.4uM; HL60; HG-U133A	GBP2 SIK3 TNFRSF21 SDHAF3 CABIN1 RAD21	2.05e-04	198	97	6	1560_DN
Drug	chlorpropamide; Down 200; 100uM; MCF7; HG-U133A	BCL2L14 CAV3 SRCAP NCAPH SPX YLPM1	2.05e-04	198	97	6	144_DN
Drug	Ticlopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; PC3; HG-U133A	ITPR1 PRDM11 SYNJ2 SUPT6H DCLRE1A EXOC7	2.05e-04	198	97	6	1895_UP
Drug	Mefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; HL60; HG-U133A	TNPO2 SPX KIF3B SUPT6H PML RAD21	2.05e-04	198	97	6	1438_DN
Drug	cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Down 200; 100uM; PC3; HG-U133A	BCL2L14 MYO9B CAV3 SRCAP SASH3 PLCG2	2.05e-04	198	97	6	664_DN
Drug	Pinacidil [85371-64-8]; Up 200; 16.4uM; PC3; HT_HG-U133A	CCDC170 DSC2 GBP1 SYNJ2 DPF3 SNAPC4	2.05e-04	198	97	6	6356_UP
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; HL60; HT_HG-U133A	ANK3 DPF3 RAB3GAP2 YLPM1 PML EPHB1	2.05e-04	198	97	6	2424_UP
Drug	Dicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A	MYO9B SIK3 TNFRSF21 SYNJ2 SYK KIF3C	2.05e-04	198	97	6	3423_DN
Drug	Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A	SRCAP CALHM2 SYNJ2 TAF1 EXOC7 PML	2.05e-04	198	97	6	6270_UP
Drug	Brinzolamide [138890-62-7]; Down 200; 10.4uM; HL60; HG-U133A	TNFRSF21 CALHM2 KIF3B YLPM1 CABIN1 PML	2.05e-04	198	97	6	1615_DN
Disease	mean platelet volume	JCAD TCF12 MYO9B PSMD2 SIK3 SRCAP TNFRSF21 SPX ZPR1 DDHD1 SYK AIF1 RASSF3 PLCG2 ALDH3A2	6.83e-07	1020	93	15	EFO_0004584
Disease	Inherited neuropathies	SIL1 ITPR1 WASHC5 ALDH3A2	7.75e-06	40	93	4	C0598589
Disease	volumetric bone mineral density	CCDC170 ADGRV1 SMC3 STARD3NL	9.44e-06	42	93	4	EFO_0007620
Disease	level of Diacylglycerol (16:0_18:2) in blood serum	SIK3 ZPR1	9.83e-06	2	93	2	OBA_2045168
Disease	Congenital muscular hypertrophy-cerebral syndrome	SMC3 RAD21	9.77e-05	5	93	2	C1802395
Disease	Cornelia de Lange Syndrome 3	SMC3 RAD21	9.77e-05	5	93	2	C1853099
Disease	Cornelia de Lange Syndrome 1	SMC3 RAD21	9.77e-05	5	93	2	C4551851
Disease	platelet component distribution width	JCAD MYO9B PSMD2 C2CD5 SYNJ2 ZPR1 DDHD1 SYK AIF1 PLCG2	1.35e-04	755	93	10	EFO_0007984
Disease	De Lange syndrome	SMC3 RAD21	1.46e-04	6	93	2	cv:C0270972
Disease	Cornelia de Lange syndrome (implicated_via_orthology)	SMC3 RAD21	1.46e-04	6	93	2	DOID:11725 (implicated_via_orthology)
Disease	cholesteryl ester 16:2 measurement	DPF3 ZPR1	2.04e-04	7	93	2	EFO_0021435
Disease	Neurodevelopmental Disorders	ASH1L SRCAP ITPR1 SMC3	2.18e-04	93	93	4	C1535926
Disease	monocyte count	JCAD ASH1L PSMD2 PSMD3 ADGRV1 NCAPH KIF3B ZPR1 YLPM1 SYK RASSF3 STARD3NL CABIN1	2.52e-04	1320	93	13	EFO_0005091
Disease	Ataxias, Hereditary	SETX SIL1	2.72e-04	8	93	2	C0004138
Disease	Cornelia De Lange Syndrome	SMC3 RAD21	2.72e-04	8	93	2	C0270972
Disease	Generalized Epilepsy with Febrile Seizures Plus	HCN1 ADGRV1	3.49e-04	9	93	2	C3502809
Disease	cholesteryl ester 20:5 measurement	JCAD ZPR1 CDH2	3.66e-04	44	93	3	EFO_0010349
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	DSC2 CDH2	4.35e-04	10	93	2	DOID:0050431 (is_implicated_in)
Disease	level of Triacylglycerol (51:3) in blood serum	SIK3 ZPR1	4.35e-04	10	93	2	OBA_2045163
Disease	developmental disorder of mental health (implicated_via_orthology)	TCF12 ASH1L SRCAP	5.03e-04	49	93	3	DOID:0060037 (implicated_via_orthology)
Disease	level of Diacylglycerol (18:1_18:1) in blood serum	SIK3 ZPR1	5.31e-04	11	93	2	OBA_2045170
Disease	glycoprotein measurement	ADGRV1 ZPR1 CDH4 ARHGAP21	5.57e-04	119	93	4	EFO_0004555
Disease	level of Diacylglycerol (18:1_18:2) in blood serum	SIK3 ZPR1	6.35e-04	12	93	2	OBA_2045171
Disease	Prostatic Neoplasms	HSP90B1 ASH1L TNFRSF21 SIL1 ITPR1 PRKCZ TAF1L PML	7.41e-04	616	93	8	C0033578
Disease	Malignant neoplasm of prostate	HSP90B1 ASH1L TNFRSF21 SIL1 ITPR1 PRKCZ TAF1L PML	7.41e-04	616	93	8	C0376358
Disease	sterol measurement	SIK3 ZPR1	7.49e-04	13	93	2	EFO_0010231
Disease	triacylglycerol 52:3 measurement	SIK3 ZPR1	1.00e-03	15	93	2	EFO_0010415
Disease	level of Triacylglycerol (53:3) in blood serum	SIK3 ZPR1	1.00e-03	15	93	2	OBA_2045165
Disease	level of triacylglycerol (56:6) in blood serum	SIK3 ZPR1	1.15e-03	16	93	2	OBA_2020007
Disease	cholesteryl ester 16:1 measurement	ZPR1 CDH2	1.15e-03	16	93	2	EFO_0010342
Disease	stem Cell Factor measurement	DPF3 ZPR1 PLCG2	1.25e-03	67	93	3	EFO_0008291
Disease	Myeloid Leukemia	SMC3 RAD21	1.45e-03	18	93	2	C0023470
Disease	Leukemia, Monocytic, Chronic	SMC3 RAD21	1.45e-03	18	93	2	C0023466
Disease	osteoporosis	CCDC170 ADGRV1 STARD3NL	1.61e-03	73	93	3	EFO_0003882
Disease	level of Phosphatidylinositol (18:0_18:2) in blood serum	SIK3 ZPR1	1.98e-03	21	93	2	OBA_2045156
Disease	triacylglycerol 54:6 measurement	SIK3 ZPR1	2.18e-03	22	93	2	EFO_0010424
Disease	Cardiomegaly	CAV3 PRKCZ CABIN1	2.24e-03	82	93	3	C0018800
Disease	Cardiac Hypertrophy	CAV3 PRKCZ CABIN1	2.24e-03	82	93	3	C1383860
Disease	serum gamma-glutamyl transferase measurement	JCAD ASH1L ITPR1 SYNJ2 CABIN1 GCN1 TOP1 ARHGAP21 EPHB1	2.38e-03	914	93	9	EFO_0004532
Disease	triacylglycerol 56:4 measurement	SIK3 ZPR1	2.59e-03	24	93	2	EFO_0010431
Disease	Acute kidney injury	GBP1 GBP3	2.81e-03	25	93	2	HP_0001919
Disease	lipid measurement, lipoprotein measurement	SIK3 ZPR1 TOP1	2.92e-03	90	93	3	EFO_0004529, EFO_0004732

Protein segments in the cluster

Peptide	Gene	Start	Entry
NRQDPDFIAELEELI	ASH1L	1281	Q9NR48
ELPADLEAILERNEN	CNTRL	2181	Q7Z7A1
NEPLRDEDDDLLQFA	ANKRD13D	476	Q6ZTN6
ILDDDIPEGDEKFQL	ADGRV1	3031	Q8WXG9
EIPLDDDDLNTIEFK	BCL2L14	11	Q9BZR8
DEAINFINEREKPLA	ALDH3A2	346	P51648
DILNFVDDLEPLDKA	DIAPH3	896	Q9NSV4
QEEDGLEFLDNLEPK	DSC2	876	Q02487
QNGEDLENLDDPEKL	APOBEC2	16	Q9Y235
DPEAQEKLIKLRDEF	NWD2	291	Q9ULI1
PELQNFLRILDKEED	RASSF3	196	Q86WH2
DNLDEFLKEFENPEV	RAD21	411	O60216
LSEPEEELLQQFKRE	LEMD3	446	Q9Y2U8
LKLANEERDAENPDE	RAB3GAP2	956	Q9H2M9
EDPNEAVREFAKEID	EPHB1	601	P54762
FKDDFILEVDRLPNE	ITPR1	2471	Q14643
NEEEDLEEDIPKRKN	DPF3	156	Q92784
NEANDPALKDELLAE	SYK	406	P43405
EFQKQDLGEPEEDRQ	JCAD	646	Q9P266
LNKDDEELIANFPVE	CALHM2	256	Q9HA72
VNEDPKDTLLREFQE	KIF3C	371	O14782
NEDEDLNPEQKIERE	TCF12	561	Q99081
RKINPIFDENDELIE	DNAH12	581	Q6ZR08
NDPDADRLAVAEKQD	PGM2	321	Q96G03
NQEPLRSLEDENKEA	NES	696	P48681
RDPKNNLEALEDFEK	LCN1	136	P31025
EKLQDEELDPEFVQQ	GBP1	251	P32455
LKEEELNPDFIEQVA	GBP2	251	P32456
AQLEKLQDEELDPEF	GBP3	246	Q9H0R5
NRLKEQIEAAENEEP	GBP7	576	Q8N8V2
PFLLKQLDDEEVSEF	GCN1	2046	Q92616
DFEELEKQIIEDNPL	PLCG2	831	P16885
LEDFADNIKNDPDKE	EXOC7	476	Q9UPT5
DFEDDPLVLNEIRED	HTATSF1	276	O43719
ESREAVEKEFEPLLN	HSP90B1	606	P14625
EEFEKRQKDNLELPS	ESS2	186	Q96DF8
EENILNELNDPLREE	HCN1	446	O60741
RLRKLDPEEEDDSFN	CABIN1	421	Q9Y6J0
ERQKFFEDILQPETE	DBNDD2	116	Q9BQY9
QEQKLFVELDLDPDF	FRMPD1	1196	Q5SYB0
FLDQEEADDQQLLEP	FNDC11	21	Q9BVV2
KQLLIDPEDDVRDNI	CDH4	766	P55283
DPEDDVRDNILKYDE	CDH4	771	P55283
NRDLEINAEEEPEKK	ANK3	11	Q12955
EIDLVNRDPKNINED	CAV3	21	P56539
PDERNDKASDEDLIL	CCDC170	181	Q8IYT3
DIDEKPDDSQEQLFF	DCLRE1A	311	Q6PJP8
YEQLLQKEEELPDER	DDHD1	556	Q8NEL9
PEEKLNDFRDEQIGQ	SDHAF3	86	Q9NRP4
VSEKEFNLDDNIPED	SASH3	41	O75995
FKFEVDDEDLQDEPL	C2CD5	56	Q86YS7
KQLLIDPEDDVRDNI	CDH2	756	P19022
DPEDDVRDNILKYDE	CDH2	761	P19022
ERNPELEFQDKVDLD	PHKB	1011	Q93100
EEEIINDENFLGKRP	TAF3	166	Q5VWG9
NPLKRKHEDDDDNDI	TAF9B	236	Q9HBM6
PEDEEKNFDQTRFLE	SPX	96	Q9BT56
LREPQEDSQKDLEND	TOR1AIP2	6	Q8NFQ8
IFDNSDNRLPIDKEE	SMC3	81	Q9UQE7
EEIPQAEDKLDRLFE	TNFRSF21	616	O75509
LEEKNEFPEDLRTEL	SYNJ2	901	O15056
PSEELLEDENAINAK	MIA3	726	Q5JRA6
QELDDAEKVQREPLL	PSMD2	171	Q13200
EKAINPLLDDDDQVA	TAF1L	1511	Q8IZX4
LEKAINPLLDDDDQV	TAF1	1491	P21675
EDRPLVFFDLKIDNE	PML	606	P29590
LQREKSEQVLDNPED	PRDM11	286	Q9NQV5
KENDLVFLAPERINE	SETX	1806	Q7Z333
LKEERQVDPLNEDVL	SIK3	336	Q9Y2K2
FRPIEELKKDFDELN	SIL1	161	Q9H173
LDQAKEEVFRLPQEE	SRCAP	2346	Q6ZRS2
DEDERQLLGEFEKEL	OS9	426	Q13438
ELFQILEDDGKLPED	STK36	86	Q9NRP7
EERLDEINKQFLDDP	AIF1	21	P55008
VLEDFPQNDDEKERL	NCAPH	51	Q15003
PERLKDLDLDAFAEE	SUPT6H	1096	Q7KZ85
EKPEEEDLRNEVLQF	ZPR1	241	O75312
PDDKFQDLVDAVRAE	THBS1	71	P07996
LDAKPELQDLDEEFR	WASHC5	71	Q12768
KDLDPNNVIIEQEER	ZCCHC17	96	Q9NP64
DIAQKLQLDSPEDAE	PSMD3	421	O43242
AEVLDRNFQLPEDLE	NXNL1	156	Q96CM4
LQDPDVREFLEKEEL	SNX1	256	Q13596
VNEDPKDALLREFQE	KIF3B	346	O15066
LDFKVLPQEAEEENR	STARD3NL	171	O95772
NELKDEDKDLFPLLE	TNPO2	571	O14787
NPEFENEELAEGEKI	PIEZO2	156	Q9H5I5
EVLREDEFSPLKNAD	UAP1	396	Q16222
SEDPEEDARLKQLQA	YLPM1	371	P49750
FAELKAIQEPDDARD	TTK	116	P33981
REAEKEIQDINQLPE	SNAPC4	236	Q5SXM2
EELLKARENPSEEAQ	SF3A3	111	Q12874
ADFIEANRKEDPLDR	ARHGAP21	1241	Q5T5U3
QELRSQEPERKFLEE	TCHH	1506	Q07283
ENKQPEDDLFDRLNT	TOP1	556	P11387
RFELINIDDLEDDPV	TCF25	61	Q9BQ70
DLDKLLDDFEQNPDE	ZFYVE16	11	Q7Z3T8
PDDEDAIKRIDQSEF	PRKCZ	561	Q05513
SEEERQEFQLKQPED	MYO9B	346	Q13459