| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | peptide lactyltransferase (CoA-dependent) activity | 4.27e-05 | 2 | 131 | 2 | GO:0120300 | |
| GeneOntologyMolecularFunction | histone H3K27 acetyltransferase activity | 4.27e-05 | 2 | 131 | 2 | GO:0044017 | |
| GeneOntologyMolecularFunction | histone H3K18 acetyltransferase activity | 1.28e-04 | 3 | 131 | 2 | GO:0043993 | |
| GeneOntologyMolecularFunction | RNA polymerase II cis-regulatory region sequence-specific DNA binding | ZNF570 ESR2 SOX30 POU2F2 TEF ZNF786 CREB5 TLX1 HIVEP3 FOXP4 PER2 NFIX TET1 ZNF81 EMX1 MNT EP300 FOXK1 TP53 TBX2 | 1.74e-04 | 1244 | 131 | 20 | GO:0000978 |
| GeneOntologyMolecularFunction | RNA polymerase II transcription regulatory region sequence-specific DNA binding | ZNF570 ESR2 SOX30 POU2F2 TEF CREBBP ZNF786 CREB5 TLX1 HIVEP3 FOXP4 PER2 NFIX TET1 ZNF81 EMX1 PRDM14 MNT EP300 FOXK1 TP53 TBX2 | 1.99e-04 | 1459 | 131 | 22 | GO:0000977 |
| GeneOntologyMolecularFunction | cis-regulatory region sequence-specific DNA binding | ZNF570 ESR2 SOX30 POU2F2 TEF ZNF786 CREB5 TLX1 HIVEP3 FOXP4 PER2 NFIX TET1 ZNF81 EMX1 MNT EP300 FOXK1 TP53 TBX2 | 2.31e-04 | 1271 | 131 | 20 | GO:0000987 |
| GeneOntologyMolecularFunction | peroxisome proliferator activated receptor binding | 3.37e-04 | 21 | 131 | 3 | GO:0042975 | |
| GeneOntologyMolecularFunction | DNA-binding transcription factor binding | TRERF1 MED16 CREBBP PARP10 PER2 NR0B1 KMT2A SPEN LRIF1 EP300 TP53 TBX2 | 4.56e-04 | 582 | 131 | 12 | GO:0140297 |
| GeneOntologyMolecularFunction | transcription corepressor activity | 7.98e-04 | 229 | 131 | 7 | GO:0003714 | |
| GeneOntologyBiologicalProcess | embryo development | HSPG2 SHROOM3 INSL3 WNK1 BIRC6 CREBBP WDPCP PTH1R EPN2 FOXP4 CMIP ARID2 BRD4 TET1 NR0B1 KMT2A TSHZ1 EMX1 PRDM14 EP300 TP53 TBX2 SOS1 | 2.69e-05 | 1437 | 129 | 23 | GO:0009790 |
| GeneOntologyBiologicalProcess | negative regulation of DNA-templated transcription | TRERF1 ESR2 SOX30 ATXN1L KANK2 CREBBP PARP10 FOXP4 PER2 NFIX ATF7IP TLE2 TET1 NR0B1 QARS1 SPEN PRDM14 MNT EP300 FOXK1 TP53 TBX2 | 5.37e-05 | 1399 | 129 | 22 | GO:0045892 |
| GeneOntologyBiologicalProcess | transcription initiation-coupled chromatin remodeling | 5.41e-05 | 65 | 129 | 5 | GO:0045815 | |
| GeneOntologyBiologicalProcess | negative regulation of RNA biosynthetic process | TRERF1 ESR2 SOX30 ATXN1L KANK2 CREBBP PARP10 FOXP4 PER2 NFIX ATF7IP TLE2 TET1 NR0B1 QARS1 SPEN PRDM14 MNT EP300 FOXK1 TP53 TBX2 | 6.23e-05 | 1413 | 129 | 22 | GO:1902679 |
| GeneOntologyBiologicalProcess | positive regulation of mitotic cytokinesis | 6.53e-05 | 13 | 129 | 3 | GO:1903490 | |
| GeneOntologyBiologicalProcess | positive regulation of gene expression, epigenetic | 6.73e-05 | 68 | 129 | 5 | GO:0141137 | |
| GeneOntologyBiologicalProcess | positive regulation of lymphocyte differentiation | 7.25e-05 | 162 | 129 | 7 | GO:0045621 | |
| GeneOntologyBiologicalProcess | rhythmic process | 9.05e-05 | 360 | 129 | 10 | GO:0048511 | |
| GeneOntologyBiologicalProcess | negative regulation of transcription by RNA polymerase II | ESR2 SOX30 ATXN1L KANK2 CREBBP FOXP4 PER2 NFIX ATF7IP TET1 NR0B1 SPEN PRDM14 MNT EP300 FOXK1 TP53 TBX2 | 9.87e-05 | 1053 | 129 | 18 | GO:0000122 |
| GeneOntologyBiologicalProcess | regulation of mitotic cytokinesis | 1.26e-04 | 16 | 129 | 3 | GO:1902412 | |
| HumanPheno | Hirsutism | 4.23e-06 | 216 | 40 | 10 | HP:0001007 | |
| HumanPheno | Abnormality of the hairline | HSPG2 CREBBP NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 TBX2 SOS1 | 1.01e-05 | 294 | 40 | 11 | HP:0009553 |
| HumanPheno | Clinodactyly | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX ARID2 BRD4 ADAMTS15 KCNN3 KMT2A SPEN EP300 SOS1 | 1.36e-05 | 574 | 40 | 15 | HP:0030084 |
| HumanPheno | Low anterior hairline | 1.40e-05 | 147 | 40 | 8 | HP:0000294 | |
| HumanPheno | Abnormality of the scalp hair | HSPG2 KANK2 CREBBP NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 TP53 TBX2 SOS1 | 1.44e-05 | 433 | 40 | 13 | HP:0100037 |
| HumanPheno | Abnormal 5th finger morphology | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX ARID2 BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 1.65e-05 | 509 | 40 | 14 | HP:0004207 |
| HumanPheno | Thick eyebrow | 1.97e-05 | 154 | 40 | 8 | HP:0000574 | |
| HumanPheno | Patent ductus arteriosus | HSPG2 SIK3 CREBBP WDPCP NFIX ARID2 KCNN3 KMT2A SPEN EP300 TBX2 SOS1 | 2.16e-05 | 382 | 40 | 12 | HP:0001643 |
| HumanPheno | Abnormal scalp morphology | HSPG2 KANK2 CREBBP NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 TP53 TBX2 SOS1 | 2.18e-05 | 450 | 40 | 13 | HP:0001965 |
| HumanPheno | Finger clinodactyly | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 2.29e-05 | 452 | 40 | 13 | HP:0040019 |
| HumanPheno | Congenital abnormal hair pattern | HSPG2 CREBBP NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 TBX2 SOS1 | 2.76e-05 | 327 | 40 | 11 | HP:0011361 |
| HumanPheno | Abnormality of the frontal hairline | 3.14e-05 | 215 | 40 | 9 | HP:0000599 | |
| HumanPheno | Cervical cord compression | 3.65e-05 | 9 | 40 | 3 | HP:0002341 | |
| HumanPheno | Long eyelashes | 5.27e-05 | 129 | 40 | 7 | HP:0000527 | |
| HumanPheno | Clinodactyly of the 5th finger | HSPG2 SIK3 CREBBP WDPCP PTH1R NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 5.58e-05 | 420 | 40 | 12 | HP:0004209 |
| HumanPheno | Neoplasm of the central nervous system | 5.60e-05 | 178 | 40 | 8 | HP:0100006 | |
| HumanPheno | Clinodactyly of hands | HSPG2 SIK3 CREBBP WDPCP PTH1R NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 5.71e-05 | 421 | 40 | 12 | HP:0001157 |
| HumanPheno | Deviation of the 5th finger | HSPG2 SIK3 CREBBP WDPCP PTH1R NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 5.71e-05 | 421 | 40 | 12 | HP:0009179 |
| HumanPheno | Generalized hirsutism | 5.72e-05 | 89 | 40 | 6 | HP:0002230 | |
| HumanPheno | Plantar crease between first and second toes | 6.01e-05 | 2 | 40 | 2 | HP:0008107 | |
| HumanPheno | Aortic isthmus hypoplasia | 6.01e-05 | 2 | 40 | 2 | HP:0034227 | |
| HumanPheno | High axial triradius | 6.01e-05 | 2 | 40 | 2 | HP:0001042 | |
| HumanPheno | Hypertrichosis | HSPG2 CREBBP WDPCP KIAA0753 NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 TP53 | 6.27e-05 | 425 | 40 | 12 | HP:0000998 |
| HumanPheno | Radial deviation of finger | HSPG2 SIK3 CREBBP WDPCP PTH1R NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 1.05e-04 | 448 | 40 | 12 | HP:0009466 |
| HumanPheno | Neoplasm of the nervous system | 1.07e-04 | 195 | 40 | 8 | HP:0004375 | |
| HumanPheno | Neoplasm by histology | HSPG2 PTH1R KIAA0753 ARID2 BRD4 NR0B1 KCNN3 SPEN EP300 TP53 SOS1 | 1.18e-04 | 383 | 40 | 11 | HP:0011792 |
| HumanPheno | Congenital malformation of the great arteries | HSPG2 ODAD1 SIK3 CREBBP WDPCP NFIX ARID2 KCNN3 KMT2A SPEN EP300 TBX2 SOS1 | 1.20e-04 | 529 | 40 | 13 | HP:0011603 |
| HumanPheno | Radial deviation of the hand or of fingers of the hand | HSPG2 SIK3 CREBBP WDPCP PTH1R NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 1.25e-04 | 456 | 40 | 12 | HP:0009485 |
| HumanPheno | Deviation of finger | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 1.41e-04 | 537 | 40 | 13 | HP:0004097 |
| HumanPheno | Duplication of phalanx of hallux | 1.54e-04 | 14 | 40 | 3 | HP:0010066 | |
| HumanPheno | Highly arched eyebrow | 1.57e-04 | 206 | 40 | 8 | HP:0002553 | |
| HumanPheno | Laryngeal cartilage malformation | 1.79e-04 | 3 | 40 | 2 | HP:0008752 | |
| HumanPheno | Phobia | 1.79e-04 | 3 | 40 | 2 | HP:5200232 | |
| HumanPheno | Agoraphobia | 1.79e-04 | 3 | 40 | 2 | HP:0000756 | |
| HumanPheno | Humoral immunodeficiency | 1.79e-04 | 3 | 40 | 2 | HP:0005363 | |
| HumanPheno | Prominent nasal septum | 1.79e-04 | 3 | 40 | 2 | HP:0005322 | |
| HumanPheno | Radial deviation of thumb terminal phalanx | 1.79e-04 | 3 | 40 | 2 | HP:0005895 | |
| HumanPheno | Duplication of phalanx of toe | 1.91e-04 | 15 | 40 | 3 | HP:0010181 | |
| HumanPheno | Abnormal hallux morphology | 1.92e-04 | 212 | 40 | 8 | HP:0001844 | |
| HumanPheno | Abnormality of skeletal maturation | HSPG2 CREBBP PTH1R NFIX ARID2 BRD4 NR0B1 KMT2A EP300 TP53 SOS1 | 1.95e-04 | 405 | 40 | 11 | HP:0000927 |
| HumanPheno | Deviation of the hand or of fingers of the hand | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX BRD4 ADAMTS15 KMT2A SPEN EP300 SOS1 | 2.32e-04 | 564 | 40 | 13 | HP:0009484 |
| HumanPheno | Abnormal morphology of the great vessels | HSPG2 ODAD1 SIK3 CREBBP WDPCP PTH1R NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 TBX2 SOS1 | 2.56e-04 | 736 | 40 | 15 | HP:0030962 |
| HumanPheno | Tooth malposition | HSPG2 CREBBP WDPCP PTH1R KIAA0753 BRD4 ADAMTS15 KCNN3 SPEN EP300 SOS1 | 2.58e-04 | 418 | 40 | 11 | HP:0000692 |
| HumanPheno | Low posterior hairline | 2.62e-04 | 117 | 40 | 6 | HP:0002162 | |
| HumanPheno | Abnormality of the posterior hairline | 2.62e-04 | 117 | 40 | 6 | HP:0030141 | |
| HumanPheno | Abnormal eyelash morphology | 2.71e-04 | 284 | 40 | 9 | HP:0000499 | |
| HumanPheno | Brachydactyly | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 SOS1 | 3.47e-04 | 670 | 40 | 14 | HP:0001156 |
| HumanPheno | Trichiasis | 3.57e-04 | 4 | 40 | 2 | HP:0001128 | |
| HumanPheno | Visceral hemangioma | 3.57e-04 | 4 | 40 | 2 | HP:0410266 | |
| HumanPheno | Talon cusp | 3.57e-04 | 4 | 40 | 2 | HP:0011087 | |
| HumanPheno | Widened distal phalanges | 3.57e-04 | 4 | 40 | 2 | HP:0006200 | |
| HumanPheno | Vascular ring | 3.57e-04 | 4 | 40 | 2 | HP:0010775 | |
| HumanPheno | Hepatic hemangioma | 3.57e-04 | 4 | 40 | 2 | HP:0031207 | |
| HumanPheno | Short digit | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 SOS1 | 3.58e-04 | 672 | 40 | 14 | HP:0011927 |
| HumanPheno | Abnormal eyebrow morphology | HSPG2 SZT2 KANK2 CREBBP WDPCP KIAA0753 NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 SOS1 | 3.69e-04 | 674 | 40 | 14 | HP:0000534 |
| HumanPheno | Abnormal hair pattern | HSPG2 CREBBP WDPCP KIAA0753 NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 TP53 TBX2 SOS1 | 3.81e-04 | 676 | 40 | 14 | HP:0010720 |
| HumanPheno | Truncal obesity | 4.04e-04 | 82 | 40 | 5 | HP:0001956 | |
| HumanPheno | Advanced eruption of teeth | 4.20e-04 | 46 | 40 | 4 | HP:0006288 | |
| HumanPheno | Conductive hearing impairment | HSPG2 ODAD1 CREBBP KIAA0753 NFIX ARID2 BRD4 TSHZ1 SPEN EP300 | 4.54e-04 | 373 | 40 | 10 | HP:0000405 |
| HumanPheno | Supernumerary tooth | 4.78e-04 | 85 | 40 | 5 | HP:0011069 | |
| HumanPheno | Cryptorchidism | HSPG2 AXL INSL3 CREBBP WDPCP KIAA0753 NFIX ARID2 BRD4 NR0B1 ADAMTS15 KMT2A SPEN EP300 SOS1 | 4.89e-04 | 780 | 40 | 15 | HP:0000028 |
| HumanPheno | Prominent digit pad | 4.95e-04 | 48 | 40 | 4 | HP:0011298 | |
| HumanPheno | Depressed nasal bridge | HSPG2 CREBBP WDPCP PTH1R KIAA0753 NFIX ARID2 BRD4 QARS1 SPEN EP300 TBX2 SOS1 | 5.22e-04 | 612 | 40 | 13 | HP:0005280 |
| HumanPheno | Flattened nasal bridge | HSPG2 CREBBP WDPCP PTH1R KIAA0753 NFIX ARID2 BRD4 QARS1 SPEN EP300 TBX2 SOS1 | 5.22e-04 | 612 | 40 | 13 | HP:0000425 |
| HumanPheno | Deep plantar creases | 5.41e-04 | 21 | 40 | 3 | HP:0001869 | |
| HumanPheno | Abnormality of upper limb joint | HSPG2 SIK3 ANKRD55 CREBBP PTH1R KIAA0753 BRD4 ADAMTS15 KMT2A SPEN LRIF1 EP300 TBX2 SOS1 | 5.91e-04 | 705 | 40 | 14 | HP:0009810 |
| HumanPheno | Papillary cystadenoma of the epididymis | 5.92e-04 | 5 | 40 | 2 | HP:0009715 | |
| HumanPheno | Supernumerary cusp | 5.92e-04 | 5 | 40 | 2 | HP:0033777 | |
| HumanPheno | Epididymal neoplasm | 5.92e-04 | 5 | 40 | 2 | HP:0030421 | |
| HumanPheno | High palate | HSPG2 SIK3 CREBBP WDPCP KIAA0753 NFIX ARID2 BRD4 ADAMTS15 KCNN3 KMT2A QARS1 SPEN EP300 SOS1 | 5.95e-04 | 794 | 40 | 15 | HP:0000218 |
| HumanPheno | Functional abnormality of the middle ear | HSPG2 ODAD1 CREBBP KIAA0753 NFIX ARID2 BRD4 TSHZ1 SPEN EP300 | 5.97e-04 | 386 | 40 | 10 | HP:0011452 |
| HumanPheno | Abnormal hair quantity | HSPG2 AXL KANK2 CREBBP WDPCP KIAA0753 NFIX ARID2 BRD4 NR0B1 KCNN3 KMT2A SPEN EP300 TP53 SOS1 | 6.13e-04 | 888 | 40 | 16 | HP:0011362 |
| HumanPheno | Long hallux | 6.23e-04 | 22 | 40 | 3 | HP:0001847 | |
| HumanPheno | Neoplasm | HSPG2 ATP7B CREBBP WDPCP PTH1R KIAA0753 CD27 NFIX ARID2 BRD4 NR0B1 KCNN3 SPEN EP300 TP53 TBX2 SOS1 | 6.46e-04 | 987 | 40 | 17 | HP:0002664 |
| HumanPheno | Pectus excavatum | 7.02e-04 | 323 | 40 | 9 | HP:0000767 | |
| HumanPheno | Puberty and gonadal disorders | HSPG2 ATP7B AXL ODAD1 ESR2 NPHP4 CREBBP WDPCP PTH1R NFIX BRD4 NR0B1 SPEN EP300 TP53 SOS1 | 7.15e-04 | 900 | 40 | 16 | HP:0008373 |
| HumanPheno | Bilateral cryptorchidism | 7.77e-04 | 54 | 40 | 4 | HP:0008689 | |
| HumanPheno | Autism | 8.45e-04 | 264 | 40 | 8 | HP:0000717 | |
| HumanPheno | Large foramen magnum | 8.84e-04 | 6 | 40 | 2 | HP:0002700 | |
| HumanPheno | Abnormal finger phalanx morphology | HSPG2 WNK1 CREBBP WDPCP PTH1R KIAA0753 NFIX BRD4 ADAMTS15 KCNN3 KMT2A SPEN EP300 TBX2 | 9.44e-04 | 738 | 40 | 14 | HP:0005918 |
| HumanPheno | Facial hypertrichosis | 9.54e-04 | 206 | 40 | 7 | HP:0002219 | |
| HumanPheno | Hypertelorism | HSPG2 SIK3 CREBBP WDPCP PTH1R KIAA0753 NFIX BRD4 ADAMTS15 KCNN3 KMT2A SPEN EP300 TBX2 SOS1 | 9.61e-04 | 830 | 40 | 15 | HP:0000316 |
| HumanPheno | Minor feet anomalies | 1.03e-03 | 26 | 40 | 3 | HP:0010613 | |
| HumanPheno | Abnormal feet morphology | 1.03e-03 | 26 | 40 | 3 | HP:0010611 | |
| HumanPheno | Annular pancreas | 1.03e-03 | 26 | 40 | 3 | HP:0001734 | |
| HumanPheno | Downslanted palpebral fissures | SZT2 CREBBP WDPCP NFIX ARID2 BRD4 KCNN3 KMT2A SPEN EP300 SOS1 | 1.14e-03 | 497 | 40 | 11 | HP:0000494 |
| HumanPheno | Abnormal epiphysis morphology | 1.21e-03 | 279 | 40 | 8 | HP:0005930 | |
| HumanPheno | Deviated nasal septum | 1.23e-03 | 7 | 40 | 2 | HP:0004411 | |
| HumanPheno | Generalized hypertrichosis | 1.23e-03 | 7 | 40 | 2 | HP:0004554 | |
| HumanPheno | Wormian bones | 1.23e-03 | 61 | 40 | 4 | HP:0002645 | |
| HumanPheno | Benign neoplasm of the central nervous system | 1.25e-03 | 105 | 40 | 5 | HP:0100835 | |
| HumanPheno | Low-set ears | HSPG2 CREBBP PTH1R KIAA0753 NFIX ARID2 BRD4 ADAMTS15 KMT2A QARS1 SPEN EP300 TBX2 SOS1 | 1.29e-03 | 761 | 40 | 14 | HP:0000369 |
| HumanPheno | Delayed skeletal maturation | 1.30e-03 | 352 | 40 | 9 | HP:0002750 | |
| HumanPheno | Flat face | 1.31e-03 | 106 | 40 | 5 | HP:0012368 | |
| HumanPheno | Abnormal heart valve morphology | HSPG2 SZT2 ODAD1 CREBBP WDPCP NFIX BRD4 ADAMTS15 SPEN EP300 TBX2 SOS1 | 1.32e-03 | 588 | 40 | 12 | HP:0001654 |
| HumanPheno | Hypoplastic ilia | 1.39e-03 | 63 | 40 | 4 | HP:0000946 | |
| HumanPheno | Short columella | 1.42e-03 | 29 | 40 | 3 | HP:0002000 | |
| HumanPheno | Broad eyebrow | 1.42e-03 | 29 | 40 | 3 | HP:0011229 | |
| HumanPheno | Neoplasm by anatomical site | HSPG2 ATP7B CREBBP WDPCP PTH1R KIAA0753 CD27 NFIX ARID2 BRD4 NR0B1 SPEN EP300 TP53 TBX2 SOS1 | 1.46e-03 | 959 | 40 | 16 | HP:0011793 |
| HumanPheno | Abnormal aortic arch morphology | 1.48e-03 | 109 | 40 | 5 | HP:0012303 | |
| MousePheno | increased megakaryocyte cell number | 1.42e-05 | 45 | 97 | 5 | MP:0008254 | |
| MousePheno | abnormal bone mineralization | 3.66e-05 | 181 | 97 | 8 | MP:0002896 | |
| MousePheno | abnormal myocardium compact layer morphology | 9.97e-05 | 67 | 97 | 5 | MP:0004056 | |
| MousePheno | abnormal neurocranium morphology | 1.03e-04 | 269 | 97 | 9 | MP:0000074 | |
| MousePheno | abnormal jugular vein morphology | 1.42e-04 | 3 | 97 | 2 | MP:0013872 | |
| MousePheno | jugular vein stenosis | 1.42e-04 | 3 | 97 | 2 | MP:0013963 | |
| MousePheno | increased leukemia incidence | 1.49e-04 | 39 | 97 | 4 | MP:0002026 | |
| MousePheno | abnormal conotruncal ridge morphology | 2.05e-04 | 17 | 97 | 3 | MP:0010585 | |
| MousePheno | abnormal conotruncus morphology | 2.45e-04 | 18 | 97 | 3 | MP:0010583 | |
| MousePheno | abnormal digestive system morphology | HSPG2 SHROOM3 INPP5D ESR2 NBEA CREBBP WDPCP PTH1R FOXP4 CMIP PER2 NFIX TET1 TSHZ1 GAST MNT EP300 TP53 TBX2 SOS1 | 2.61e-04 | 1233 | 97 | 20 | MP:0000462 |
| MousePheno | abnormal hematopoietic stem cell physiology | 2.61e-04 | 45 | 97 | 4 | MP:0010763 | |
| MousePheno | thin myocardium compact layer | 2.84e-04 | 46 | 97 | 4 | MP:0004057 | |
| MousePheno | increased tumor incidence | IL12RB2 INPP5D ESR2 CREBBP PTH1R HIVEP3 PER2 TET1 NR0B1 KMT2A GAST TP53 | 2.95e-04 | 530 | 97 | 12 | MP:0002020 |
| MousePheno | abnormal cartilaginous joint morphology | 3.07e-04 | 85 | 97 | 5 | MP:0030875 | |
| MousePheno | increased classified tumor incidence | IL12RB2 INPP5D ESR2 CREBBP PTH1R HIVEP3 PER2 TET1 KMT2A TP53 | 3.07e-04 | 381 | 97 | 10 | MP:0010273 |
| MousePheno | myocardium hypoplasia | 3.24e-04 | 86 | 97 | 5 | MP:0010500 | |
| MousePheno | abnormal megakaryocyte morphology | 3.24e-04 | 86 | 97 | 5 | MP:0002417 | |
| MousePheno | abnormal classified tumor incidence | IL12RB2 INPP5D ESR2 CREBBP PTH1R HIVEP3 PER2 TET1 KMT2A TP53 | 3.27e-04 | 384 | 97 | 10 | MP:0020188 |
| MousePheno | thin ventricle myocardium compact layer | 3.39e-04 | 20 | 97 | 3 | MP:0010556 | |
| MousePheno | abnormal cardiovascular development | HSPG2 IL12RB2 SHROOM3 WNK1 BIRC6 CREBBP WDPCP FOXP4 CMIP ARID2 RBM24 SPEN EP300 TP53 TBX2 | 3.97e-04 | 802 | 97 | 15 | MP:0002925 |
| MousePheno | abnormal bone ossification | HSPG2 ESR2 IRS1 SIK3 CREBBP PTH1R HIVEP3 KIAA1549L PER2 NFIX | 4.08e-04 | 395 | 97 | 10 | MP:0008271 |
| MousePheno | abnormal granulocyte number | ATP7B ARHGEF5 INPP5D TICAM1 ESR2 SIK3 CREBBP TLX1 TET1 KMT2A RFT1 ARHGAP21 EP300 TP53 SOS1 | 4.13e-04 | 805 | 97 | 15 | MP:0020201 |
| MousePheno | abnormal tumor incidence | IL12RB2 INPP5D ESR2 CREBBP PTH1R HIVEP3 CMIP PER2 TET1 NR0B1 KMT2A GAST TP53 | 4.30e-04 | 635 | 97 | 13 | MP:0002019 |
| Domain | Nuc_rcpt_coact_CREBbp | 4.96e-05 | 2 | 132 | 2 | IPR014744 | |
| Domain | ZnF_TAZ | 4.96e-05 | 2 | 132 | 2 | SM00551 | |
| Domain | - | 4.96e-05 | 2 | 132 | 2 | 1.20.1020.10 | |
| Domain | RING_CBP-p300 | 4.96e-05 | 2 | 132 | 2 | IPR010303 | |
| Domain | - | 4.96e-05 | 2 | 132 | 2 | 1.10.1630.10 | |
| Domain | Creb_binding | 4.96e-05 | 2 | 132 | 2 | PF09030 | |
| Domain | zf-TAZ | 4.96e-05 | 2 | 132 | 2 | PF02135 | |
| Domain | ZF_TAZ | 4.96e-05 | 2 | 132 | 2 | PS50134 | |
| Domain | KAT11 | 4.96e-05 | 2 | 132 | 2 | SM01250 | |
| Domain | Znf_TAZ | 4.96e-05 | 2 | 132 | 2 | IPR000197 | |
| Domain | KIX | 4.96e-05 | 2 | 132 | 2 | PF02172 | |
| Domain | HAT_KAT11 | 4.96e-05 | 2 | 132 | 2 | PF08214 | |
| Domain | KIX | 4.96e-05 | 2 | 132 | 2 | PS50952 | |
| Domain | CBP_P300_HAT | 4.96e-05 | 2 | 132 | 2 | IPR031162 | |
| Domain | DUF902 | 4.96e-05 | 2 | 132 | 2 | PF06001 | |
| Domain | - | 4.96e-05 | 2 | 132 | 2 | 1.10.246.20 | |
| Domain | Histone_AcTrfase_Rtt109/CBP | 4.96e-05 | 2 | 132 | 2 | IPR013178 | |
| Domain | KIX_dom | 4.96e-05 | 2 | 132 | 2 | IPR003101 | |
| Domain | CBP_P300_HAT | 4.96e-05 | 2 | 132 | 2 | PS51727 | |
| Domain | NPIP | 1.19e-04 | 14 | 132 | 3 | IPR009443 | |
| Domain | BROMODOMAIN_2 | 1.97e-04 | 41 | 132 | 4 | PS50014 | |
| Domain | Bromodomain | 2.17e-04 | 42 | 132 | 4 | IPR001487 | |
| Domain | BROMO | 2.17e-04 | 42 | 132 | 4 | SM00297 | |
| Domain | - | 2.17e-04 | 42 | 132 | 4 | 1.20.920.10 | |
| Domain | Nuc_rcpt_coact | 7.30e-04 | 6 | 132 | 2 | IPR009110 | |
| Domain | Bromodomain_CS | 7.97e-04 | 26 | 132 | 3 | IPR018359 | |
| Domain | PH | 8.17e-04 | 278 | 132 | 8 | SM00233 | |
| Domain | PH_DOMAIN | 8.37e-04 | 279 | 132 | 8 | PS50003 | |
| Domain | PH_domain | 8.56e-04 | 280 | 132 | 8 | IPR001849 | |
| Pathway | KEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY | 1.99e-05 | 9 | 89 | 3 | M47451 | |
| Pathway | BIOCARTA_CARM_ER_PATHWAY | 2.00e-05 | 26 | 89 | 4 | M2499 | |
| Pathway | REACTOME_SIGNALING_BY_NOTCH1 | 1.02e-04 | 74 | 89 | 5 | M616 | |
| Pathway | WP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY | 1.17e-04 | 301 | 89 | 9 | MM15983 | |
| Pathway | PID_MYC_ACTIV_PATHWAY | 1.40e-04 | 79 | 89 | 5 | M66 | |
| Pathway | REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA | 1.55e-04 | 17 | 89 | 3 | M48025 | |
| Pathway | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | 2.34e-04 | 48 | 89 | 4 | M611 | |
| Pathway | KEGG_PROSTATE_CANCER | 2.45e-04 | 89 | 89 | 5 | M13191 | |
| Pathway | WP_IL4_SIGNALING | 3.69e-04 | 54 | 89 | 4 | M39720 | |
| Pathway | WP_HEPATITIS_B_INFECTION | 3.82e-04 | 151 | 89 | 6 | M39801 | |
| Pathway | REACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES | 3.89e-04 | 5 | 89 | 2 | M48020 | |
| Pathway | REACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES | 3.89e-04 | 5 | 89 | 2 | M48023 | |
| Pathway | BIOCARTA_PELP1_PATHWAY | 3.89e-04 | 5 | 89 | 2 | MM1575 | |
| Pathway | REACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION | 3.89e-04 | 5 | 89 | 2 | M27228 | |
| Pubmed | Interaction network of human early embryonic transcription factors. | TRERF1 ATXN1L CREBBP PRR12 FOXP4 ARID2 TET1 KMT2A SPEN LRIF1 EP300 FOXK1 TBX2 | 1.88e-09 | 351 | 139 | 13 | 38297188 |
| Pubmed | A dual-activity topoisomerase complex regulates mRNA translation and turnover. | HSPG2 CRYBG2 SHROOM3 SZT2 IRS1 WNK1 NPHP4 BIRC6 HIVEP3 PRR12 PER2 BRD4 PCNX1 DTX2 MAPKBP1 SPEN ARHGAP21 EP300 CEP170B FOXK1 RAB11FIP3 | 3.32e-09 | 1105 | 139 | 21 | 35748872 |
| Pubmed | A census of human transcription factors: function, expression and evolution. | TRERF1 ESR2 SOX30 POU2F2 TEF CREB5 TLX1 HIVEP3 FOXP4 NFIX NR0B1 KMT2A TSHZ1 EMX1 MNT FOXK1 MBNL3 TP53 TBX2 | 4.29e-09 | 908 | 139 | 19 | 19274049 |
| Pubmed | Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. | POU2F2 ECT2 KANK2 LENG9 CREBBP CREB5 FOXP4 NFIX FBXO42 TSHZ1 KIF5B QARS1 SPEN MNT EP300 FOXK1 TP53 TBX2 | 1.07e-08 | 857 | 139 | 18 | 25609649 |
| Pubmed | 5.04e-08 | 10 | 139 | 4 | 18765668 | ||
| Pubmed | 6.25e-08 | 3 | 139 | 3 | 20859991 | ||
| Pubmed | 6.25e-08 | 3 | 139 | 3 | 9194564 | ||
| Pubmed | p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300. | 6.25e-08 | 3 | 139 | 3 | 11782467 | |
| Pubmed | Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation. | 6.25e-08 | 3 | 139 | 3 | 14759370 | |
| Pubmed | 6.25e-08 | 3 | 139 | 3 | 19166313 | ||
| Pubmed | 6.25e-08 | 3 | 139 | 3 | 11349124 | ||
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | SHROOM3 ARHGEF5 IRS1 SIK3 WNK1 ECT2 EPN2 KIAA0753 PIK3R4 BRD4 TET1 KMT2A KIF5B ARHGAP21 CEP170B FOXK1 TP53 | 6.88e-08 | 861 | 139 | 17 | 36931259 |
| Pubmed | TRERF1 MED16 ATXN1L CREBBP PRR12 FOXP4 NFIX BRD4 KMT2A FOXK1 | 1.39e-07 | 268 | 139 | 10 | 33640491 | |
| Pubmed | Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53. | 2.49e-07 | 4 | 139 | 3 | 16611888 | |
| Pubmed | Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. | 2.49e-07 | 4 | 139 | 3 | 18552833 | |
| Pubmed | 2.49e-07 | 4 | 139 | 3 | 16537920 | ||
| Pubmed | Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein. | 2.49e-07 | 4 | 139 | 3 | 19651603 | |
| Pubmed | 2.49e-07 | 4 | 139 | 3 | 9194565 | ||
| Pubmed | 2.49e-07 | 4 | 139 | 3 | 16135789 | ||
| Pubmed | Molecular characterization of HTLV-1 Tax interaction with the KIX domain of CBP/p300. | 2.49e-07 | 4 | 139 | 3 | 17707401 | |
| Pubmed | 2.49e-07 | 4 | 139 | 3 | 11196199 | ||
| Pubmed | p300/MDM2 complexes participate in MDM2-mediated p53 degradation. | 2.49e-07 | 4 | 139 | 3 | 9809062 | |
| Pubmed | 2.49e-07 | 4 | 139 | 3 | 19880525 | ||
| Pubmed | Inactivating mutations of acetyltransferase genes in B-cell lymphoma. | 2.49e-07 | 4 | 139 | 3 | 21390126 | |
| Pubmed | TRERF1 HSPG2 CAD ATXN1L CREBBP TLX1 PRR12 FOXP4 NFIX ATF7IP ARID2 OTUD4 KMT2A QARS1 SPEN MNT LRIF1 EP300 FOXK1 TP53 FILIP1L | 2.62e-07 | 1429 | 139 | 21 | 35140242 | |
| Pubmed | TRERF1 CAD MED16 INPP5D BCAT1 ATXN1L CREBBP PRR12 ARID2 BRD4 KMT2A KIF5B SPEN MNT LRIF1 EP300 FOXK1 TP53 | 4.59e-07 | 1103 | 139 | 18 | 34189442 | |
| Pubmed | Induction of SOX4 by DNA damage is critical for p53 stabilization and function. | 6.21e-07 | 5 | 139 | 3 | 19234109 | |
| Pubmed | 6.21e-07 | 5 | 139 | 3 | 14722092 | ||
| Pubmed | 6.21e-07 | 5 | 139 | 3 | 25451029 | ||
| Pubmed | 6.21e-07 | 5 | 139 | 3 | 21670263 | ||
| Pubmed | 6.21e-07 | 5 | 139 | 3 | 15225550 | ||
| Pubmed | 6.21e-07 | 5 | 139 | 3 | 16543236 | ||
| Pubmed | 6.21e-07 | 5 | 139 | 3 | 15013777 | ||
| Pubmed | 6.21e-07 | 5 | 139 | 3 | 19448667 | ||
| Pubmed | Identification and functional characterization of transcriptional activators in human cells. | CREBBP PRR12 FOXP4 TSR1 NFIX ATF7IP ARID2 BRD4 TSHZ1 EP300 FOXK1 | 6.48e-07 | 398 | 139 | 11 | 35016035 |
| Pubmed | WNK1 NPHP4 BIRC6 EPN2 KIAA0753 HIVEP3 PRR12 KRBA1 CMIP ARID2 FBXO42 DTX2 | 7.55e-07 | 493 | 139 | 12 | 15368895 | |
| Pubmed | Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode. | 9.04e-07 | 19 | 139 | 4 | 27626385 | |
| Pubmed | TRERF1 ESR2 POU2F2 TEF LENG9 ZNF786 HIVEP3 KRBA1 ARID2 BRD4 NR0B1 MNT FOXK1 MBNL3 TP53 | 9.23e-07 | 808 | 139 | 15 | 20412781 | |
| Pubmed | CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53. | 1.24e-06 | 6 | 139 | 3 | 19805293 | |
| Pubmed | 1.24e-06 | 6 | 139 | 3 | 18485870 | ||
| Pubmed | 1.24e-06 | 6 | 139 | 3 | 32494626 | ||
| Pubmed | The CBP/p300 TAZ1 domain in its native state is not a binding partner of MDM2. | 2.16e-06 | 7 | 139 | 3 | 15154850 | |
| Pubmed | 3.45e-06 | 8 | 139 | 3 | 10490106 | ||
| Pubmed | Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer. | 3.59e-06 | 102 | 139 | 6 | 15778465 | |
| Pubmed | SIK3 WNK1 CREBBP KIAA1549L ATF7IP ARID2 KIF5B WIPF2 EP300 RNF111 SOS1 | 4.45e-06 | 486 | 139 | 11 | 20936779 | |
| Pubmed | 7.34e-06 | 10 | 139 | 3 | 25314079 | ||
| Pubmed | Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. | TRERF1 SHROOM3 ARHGEF5 INPP5D WNK1 ARID2 TSHZ1 SPEN TP53 SOS1 | 9.71e-06 | 430 | 139 | 10 | 35044719 |
| Pubmed | IL12RB2 ATP7B HAUS5 SIK3 KANK2 CREBBP FOXP4 HMCN2 ARID2 BRD4 EP300 CEP170B FOXK1 TP53 TBX2 SOS1 | 1.07e-05 | 1116 | 139 | 16 | 31753913 | |
| Pubmed | MED16 HAUS5 WNK1 KANK2 CREBBP KIAA0753 TSR1 KMT2A KIF5B SPEN LRIF1 EP300 | 1.17e-05 | 645 | 139 | 12 | 25281560 | |
| Pubmed | An atlas of combinatorial transcriptional regulation in mouse and man. | MED16 ESR2 TEF ANKRD55 CREBBP TLX1 PER2 TLE2 EMX1 SPEN PRDM14 EP300 TP53 TBX2 | 1.21e-05 | 877 | 139 | 14 | 20211142 |
| Pubmed | Histone acetyltransferase-dependent chromatin remodeling and the vascular clock. | 1.34e-05 | 12 | 139 | 3 | 14645221 | |
| Pubmed | CAD HAUS5 CREBBP ARID2 BRD4 TET1 KMT2A KIF5B SPEN EP300 TP53 | 1.39e-05 | 549 | 139 | 11 | 38280479 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 27881875 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 23677568 | ||
| Pubmed | Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias. | 1.59e-05 | 2 | 139 | 2 | 23100278 | |
| Pubmed | Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia. | 1.59e-05 | 2 | 139 | 2 | 34845315 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 12124344 | ||
| Pubmed | Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease. | 1.59e-05 | 2 | 139 | 2 | 15767257 | |
| Pubmed | Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization. | 1.59e-05 | 2 | 139 | 2 | 21127074 | |
| Pubmed | Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305. | 1.59e-05 | 2 | 139 | 2 | 12724314 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 29190668 | ||
| Pubmed | A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3. | 1.59e-05 | 2 | 139 | 2 | 36685041 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 26976603 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 12205094 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 20717166 | ||
| Pubmed | Mapping the interactions of the p53 transactivation domain with the KIX domain of CBP. | 1.59e-05 | 2 | 139 | 2 | 19220000 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 25893291 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 11559821 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 18391200 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 19822209 | ||
| Pubmed | CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement. | 1.59e-05 | 2 | 139 | 2 | 21847097 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 25435374 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 25411341 | ||
| Pubmed | p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes. | 1.59e-05 | 2 | 139 | 2 | 34813504 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 20301699 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 35502657 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 31898871 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 26871946 | ||
| Pubmed | Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity. | 1.59e-05 | 2 | 139 | 2 | 30888860 | |
| Pubmed | Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer. | 1.59e-05 | 2 | 139 | 2 | 27881443 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 30953353 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 21803292 | ||
| Pubmed | BRD4-mediated repression of p53 is a target for combination therapy in AML. | 1.59e-05 | 2 | 139 | 2 | 33431824 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 9811832 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 24089570 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 28596680 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 15706485 | ||
| Pubmed | AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer. | 1.59e-05 | 2 | 139 | 2 | 39266679 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 22303793 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 34732714 | ||
| Pubmed | Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition. | 1.59e-05 | 2 | 139 | 2 | 34019788 | |
| Pubmed | Structural features of human histone acetyltransferase p300 and its complex with p53. | 1.59e-05 | 2 | 139 | 2 | 23010591 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 9018065 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 19144982 | ||
| Pubmed | CBP/p300 acetyltransferase activity in hematologic malignancies. | 1.59e-05 | 2 | 139 | 2 | 27380996 | |
| Pubmed | CREBBP and p300 lysine acetyl transferases in the DNA damage response. | 1.59e-05 | 2 | 139 | 2 | 29170789 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 21555743 | ||
| Pubmed | CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells. | 1.59e-05 | 2 | 139 | 2 | 12646247 | |
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 27088856 | ||
| Pubmed | 1.59e-05 | 2 | 139 | 2 | 11867645 | ||
| Interaction | TLE3 interactions | TRERF1 ATXN1L CREBBP TLX1 PRR12 NFIX TLE2 ARID2 BRD4 NR0B1 OTUD4 KMT2A SPEN EP300 TP53 | 3.19e-08 | 376 | 134 | 15 | int:TLE3 |
| Interaction | CTBP1 interactions | ESR2 ATXN1L ECT2 CREBBP CREB5 PRR12 BRD4 KMT2A TSHZ1 DTX2 SPEN EP300 FOXK1 TP53 RNF111 | 8.72e-08 | 406 | 134 | 15 | int:CTBP1 |
| Interaction | CRX interactions | TRERF1 SZT2 ATXN1L KANK2 CREBBP PRR12 FOXP4 ARID2 SPEN LRIF1 EP300 FOXK1 | 1.34e-07 | 254 | 134 | 12 | int:CRX |
| Interaction | BAG2 interactions | MED16 AXL HAUS5 WNK1 NPHP4 ECT2 CREBBP KIAA0753 TLE2 BRD4 OTUD4 PHLPP1 SPEN ARHGAP21 EP300 FOXK1 MBNL3 TP53 | 1.66e-07 | 622 | 134 | 18 | int:BAG2 |
| Interaction | NFIB interactions | 4.59e-07 | 142 | 134 | 9 | int:NFIB | |
| Interaction | KLF5 interactions | 7.37e-07 | 195 | 134 | 10 | int:KLF5 | |
| Interaction | SP7 interactions | TRERF1 CAD ATXN1L CREBBP PRR12 FOXP4 NFIX ARID2 QARS1 EP300 FOXK1 FILIP1L | 9.14e-07 | 304 | 134 | 12 | int:SP7 |
| Interaction | NCOR1 interactions | ESR2 ATXN1L CREBBP TLX1 NFIX BRD4 DTX2 KIF5B SPEN EP300 FOXK1 TP53 TBX2 | 9.42e-07 | 363 | 134 | 13 | int:NCOR1 |
| Interaction | NCOR2 interactions | ESR2 ATXN1L CREBBP TLX1 NFIX BRD4 FBXO42 DTX2 SPEN EP300 TP53 | 1.57e-06 | 264 | 134 | 11 | int:NCOR2 |
| Interaction | EGR2 interactions | 2.17e-06 | 171 | 134 | 9 | int:EGR2 | |
| Interaction | FHL2 interactions | SOX30 WNK1 KANK2 ANKRD55 CREBBP DTX2 KIF5B SPEN LRIF1 EP300 B3GAT2 FOXK1 RNF111 | 2.47e-06 | 396 | 134 | 13 | int:FHL2 |
| Interaction | HOXA10 interactions | 3.50e-06 | 62 | 134 | 6 | int:HOXA10 | |
| Interaction | TOP3B interactions | HSPG2 CRYBG2 SHROOM3 CAD SZT2 IRS1 WNK1 NPHP4 KANK2 BIRC6 HIVEP3 PRR12 PER2 BRD4 OTUD4 PCNX1 DTX2 MAPKBP1 QARS1 SPEN ARHGAP21 EP300 CEP170B FOXK1 TP53 RAB11FIP3 | 3.77e-06 | 1470 | 134 | 26 | int:TOP3B |
| Interaction | SOX9 interactions | 3.83e-06 | 97 | 134 | 7 | int:SOX9 | |
| Interaction | SOX15 interactions | 4.67e-06 | 141 | 134 | 8 | int:SOX15 | |
| Interaction | NCOA2 interactions | 4.67e-06 | 141 | 134 | 8 | int:NCOA2 | |
| Interaction | IRF7 interactions | 4.70e-06 | 100 | 134 | 7 | int:IRF7 | |
| Interaction | FEV interactions | 8.81e-06 | 203 | 134 | 9 | int:FEV | |
| Interaction | TBR1 interactions | 1.06e-05 | 113 | 134 | 7 | int:TBR1 | |
| Interaction | NFIC interactions | 1.16e-05 | 210 | 134 | 9 | int:NFIC | |
| Interaction | YWHAH interactions | SHROOM3 ARHGEF5 ESR2 IRS1 SIK3 WNK1 ATXN1L ECT2 ANKRD55 CREBBP PTH1R EPN2 KIAA0753 PIK3R4 BRD4 TET1 KMT2A KIF5B ARHGAP21 CEP170B FOXK1 | 1.23e-05 | 1102 | 134 | 21 | int:YWHAH |
| Interaction | KDM6A interactions | 1.30e-05 | 162 | 134 | 8 | int:KDM6A | |
| Interaction | CCT8 interactions | CAD ESR2 SIK3 ANKRD55 PIK3R4 PER2 TSR1 TLE2 BRD4 FBXO42 PHLPP1 KIF5B QARS1 TP53 | 1.83e-05 | 550 | 134 | 14 | int:CCT8 |
| Interaction | ERG interactions | 1.87e-05 | 223 | 134 | 9 | int:ERG | |
| Interaction | YWHAZ interactions | SHROOM3 CAD AXL ARHGEF5 ESR2 IRS1 SIK3 WNK1 ECT2 KANK2 ANKRD55 EPN2 PER2 BRD4 OSBPL7 OTUD4 KMT2A KIF5B ARHGAP21 EP300 CEP170B FOXK1 TP53 | 1.88e-05 | 1319 | 134 | 23 | int:YWHAZ |
| Interaction | KLF3 interactions | 2.22e-05 | 228 | 134 | 9 | int:KLF3 | |
| Interaction | TLX1 interactions | 2.27e-05 | 175 | 134 | 8 | int:TLX1 | |
| Interaction | PAX9 interactions | 2.63e-05 | 130 | 134 | 7 | int:PAX9 | |
| Interaction | PRR12 interactions | 2.68e-05 | 88 | 134 | 6 | int:PRR12 | |
| Interaction | FLNA interactions | AXL ACAD10 NPHP4 ECT2 ANKRD55 CMIP PER2 TLE2 BRD4 PHLPP1 KIF5B QARS1 ARHGAP21 EP300 TP53 | 2.75e-05 | 648 | 134 | 15 | int:FLNA |
| Interaction | NFIA interactions | 3.78e-05 | 188 | 134 | 8 | int:NFIA | |
| Interaction | MEIS2 interactions | 3.89e-05 | 94 | 134 | 6 | int:MEIS2 | |
| Interaction | EPPK1 interactions | 3.93e-05 | 189 | 134 | 8 | int:EPPK1 | |
| Interaction | PIAS3 interactions | 4.13e-05 | 95 | 134 | 6 | int:PIAS3 | |
| Interaction | FYCO1 interactions | 6.51e-05 | 103 | 134 | 6 | int:FYCO1 | |
| Interaction | HOXB2 interactions | 9.33e-05 | 36 | 134 | 4 | int:HOXB2 | |
| Interaction | HNF4A interactions | 9.50e-05 | 275 | 134 | 9 | int:HNF4A | |
| Interaction | ARID1A interactions | 9.77e-05 | 276 | 134 | 9 | int:ARID1A | |
| Interaction | PAX8 interactions | 9.87e-05 | 111 | 134 | 6 | int:PAX8 | |
| Interaction | FOSL1 interactions | 1.03e-04 | 70 | 134 | 5 | int:FOSL1 | |
| Interaction | S100P interactions | 1.06e-04 | 279 | 134 | 9 | int:S100P | |
| Interaction | HSP90B1 interactions | CAD AXL ESR2 NPHP4 ECT2 ANKRD55 CCDC112 PER2 TSR1 TLE2 BRD4 KMT2A QARS1 TP53 | 1.11e-04 | 650 | 134 | 14 | int:HSP90B1 |
| Interaction | NUP98 interactions | 1.14e-04 | 220 | 134 | 8 | int:NUP98 | |
| Interaction | EGR1 interactions | 1.18e-04 | 72 | 134 | 5 | int:EGR1 | |
| Interaction | EPG5 interactions | 1.23e-04 | 15 | 134 | 3 | int:EPG5 | |
| Interaction | TBXT interactions | 1.26e-04 | 116 | 134 | 6 | int:TBXT | |
| Interaction | RORA interactions | 1.28e-04 | 39 | 134 | 4 | int:RORA | |
| Interaction | NCOA3 interactions | 1.29e-04 | 224 | 134 | 8 | int:NCOA3 | |
| Interaction | FCRL6 interactions | 1.31e-04 | 3 | 134 | 2 | int:FCRL6 | |
| Interaction | YEATS2 interactions | 1.38e-04 | 169 | 134 | 7 | int:YEATS2 | |
| Interaction | KMT2D interactions | 1.38e-04 | 169 | 134 | 7 | int:KMT2D | |
| Interaction | NFIX interactions | 1.41e-04 | 227 | 134 | 8 | int:NFIX | |
| Interaction | PLEC interactions | ESR2 WNK1 NPHP4 ECT2 PER2 BRD4 PHLPP1 QARS1 FOXK1 TP53 FILIP1L | 1.44e-04 | 430 | 134 | 11 | int:PLEC |
| Interaction | TACC2 interactions | 1.62e-04 | 77 | 134 | 5 | int:TACC2 | |
| Interaction | SP1 interactions | 1.68e-04 | 365 | 134 | 10 | int:SP1 | |
| Interaction | CCT4 interactions | CAD ESR2 SIK3 ECT2 ANKRD55 PIK3R4 TSR1 TLE2 BRD4 FBXO42 PHLPP1 TP53 | 1.71e-04 | 515 | 134 | 12 | int:CCT4 |
| Interaction | JDP2 interactions | 1.72e-04 | 42 | 134 | 4 | int:JDP2 | |
| Interaction | PAX7 interactions | 1.82e-04 | 124 | 134 | 6 | int:PAX7 | |
| Interaction | HNF1A interactions | 1.94e-04 | 80 | 134 | 5 | int:HNF1A | |
| Interaction | ELF1 interactions | 1.98e-04 | 126 | 134 | 6 | int:ELF1 | |
| Interaction | KAT2A interactions | 2.04e-04 | 180 | 134 | 7 | int:KAT2A | |
| Interaction | SMTN interactions | 2.06e-04 | 44 | 134 | 4 | int:SMTN | |
| Interaction | VDR interactions | 2.07e-04 | 127 | 134 | 6 | int:VDR | |
| Interaction | SOX7 interactions | 2.18e-04 | 82 | 134 | 5 | int:SOX7 | |
| Interaction | PPARGC1A interactions | 2.18e-04 | 82 | 134 | 5 | int:PPARGC1A | |
| Interaction | FOSL2 interactions | 2.31e-04 | 83 | 134 | 5 | int:FOSL2 | |
| Interaction | SIN3A interactions | 2.32e-04 | 380 | 134 | 10 | int:SIN3A | |
| Interaction | LHX3 interactions | 2.41e-04 | 185 | 134 | 7 | int:LHX3 | |
| Interaction | HIVEP1 interactions | 2.50e-04 | 186 | 134 | 7 | int:HIVEP1 | |
| Interaction | SMARCC1 interactions | 2.52e-04 | 384 | 134 | 10 | int:SMARCC1 | |
| Interaction | DBP interactions | 2.58e-04 | 19 | 134 | 3 | int:DBP | |
| Interaction | IRF4 interactions | 2.58e-04 | 85 | 134 | 5 | int:IRF4 | |
| Interaction | PAX2 interactions | 2.58e-04 | 85 | 134 | 5 | int:PAX2 | |
| Interaction | NPIPB13 interactions | 2.61e-04 | 4 | 134 | 2 | int:NPIPB13 | |
| Interaction | KANSL3 interactions | 2.73e-04 | 86 | 134 | 5 | int:KANSL3 | |
| Interaction | GSC interactions | 2.88e-04 | 87 | 134 | 5 | int:GSC | |
| Interaction | SMG7 interactions | 2.88e-04 | 319 | 134 | 9 | int:SMG7 | |
| Interaction | CREB1 interactions | 3.03e-04 | 254 | 134 | 8 | int:CREB1 | |
| Interaction | RBPJ interactions | 3.03e-04 | 254 | 134 | 8 | int:RBPJ | |
| Interaction | CNTRL interactions | 3.12e-04 | 193 | 134 | 7 | int:CNTRL | |
| Interaction | PLAGL1 interactions | 3.50e-04 | 21 | 134 | 3 | int:PLAGL1 | |
| Interaction | KLF8 interactions | 3.61e-04 | 329 | 134 | 9 | int:KLF8 | |
| Interaction | TADA3 interactions | 3.63e-04 | 141 | 134 | 6 | int:TADA3 | |
| Interaction | FOXI1 interactions | 3.73e-04 | 92 | 134 | 5 | int:FOXI1 | |
| Interaction | MED25 interactions | 3.92e-04 | 93 | 134 | 5 | int:MED25 | |
| Interaction | ZNF148 interactions | 4.07e-04 | 144 | 134 | 6 | int:ZNF148 | |
| Interaction | SMC3 interactions | 4.07e-04 | 408 | 134 | 10 | int:SMC3 | |
| Interaction | YWHAB interactions | SHROOM3 AXL ARHGEF5 ESR2 IRS1 SIK3 WNK1 ECT2 ANKRD55 EPN2 PIK3R4 KMT2A KIF5B ARHGAP21 CEP170B FOXK1 TP53 | 4.07e-04 | 1014 | 134 | 17 | int:YWHAB |
| Interaction | WDR33 interactions | 4.22e-04 | 145 | 134 | 6 | int:WDR33 | |
| Interaction | CLTC interactions | CAD WNK1 ECT2 ANKRD55 EPN2 PER2 TLE2 BRD4 FBXO42 PHLPP1 QARS1 EP300 TP53 | 4.32e-04 | 655 | 134 | 13 | int:CLTC |
| Interaction | SOX17 interactions | 4.33e-04 | 95 | 134 | 5 | int:SOX17 | |
| Interaction | HDC interactions | 4.33e-04 | 5 | 134 | 2 | int:HDC | |
| Interaction | SPO11 interactions | 4.33e-04 | 5 | 134 | 2 | int:SPO11 | |
| Interaction | MYH9 interactions | SHROOM3 CAD ESR2 WNK1 NPHP4 ECT2 CREBBP TSR1 BRD4 PHLPP1 KIF5B ARHGAP21 EP300 TP53 | 5.04e-04 | 754 | 134 | 14 | int:MYH9 |
| Interaction | SMARCA2 interactions | 5.20e-04 | 346 | 134 | 9 | int:SMARCA2 | |
| Interaction | TFAP2B interactions | 5.25e-04 | 24 | 134 | 3 | int:TFAP2B | |
| Interaction | WWTR1 interactions | 5.29e-04 | 422 | 134 | 10 | int:WWTR1 | |
| Interaction | USP9X interactions | 5.29e-04 | 422 | 134 | 10 | int:USP9X | |
| Interaction | TFAP4 interactions | 5.61e-04 | 153 | 134 | 6 | int:TFAP4 | |
| Interaction | CAPN1 interactions | 5.96e-04 | 215 | 134 | 7 | int:CAPN1 | |
| Cytoband | 19p13.3 | 7.05e-07 | 237 | 139 | 8 | 19p13.3 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr19p13 | MED16 TICAM1 INSL3 CAPS ZNRF4 KANK2 NFIX TLE2 BRD4 GRIN3B MADCAM1 | 3.37e-05 | 797 | 139 | 11 | chr19p13 |
| Cytoband | 16p12.2 | 1.96e-04 | 37 | 139 | 3 | 16p12.2 | |
| GeneFamily | Immunoglobulin like domain containing | 4.30e-04 | 193 | 91 | 6 | 594 | |
| Coexpression | DAZARD_RESPONSE_TO_UV_NHEK_DN | 4.82e-06 | 300 | 139 | 10 | M8702 | |
| ToppCell | nucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2 | 5.51e-10 | 193 | 139 | 10 | 779276e775cb2492e8dd36436295a536084a6415 | |
| ToppCell | 10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue | 1.41e-07 | 188 | 139 | 8 | ab9b725d6e0cdab8e9ddda6dee09e14730e9a578 | |
| ToppCell | TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9 | 1.99e-06 | 186 | 139 | 7 | 03db813598b67b1e08f759758a1c2023396921fa | |
| ToppCell | LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.00e-05 | 157 | 139 | 6 | bd45590da540a557dc8096980a45220fccb99505 | |
| ToppCell | LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2 | 1.00e-05 | 157 | 139 | 6 | 00c9a58b033b8b95b0d838f233dd077b62d8b02a | |
| ToppCell | 390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells) | 1.20e-05 | 162 | 139 | 6 | 45be019b50e3727fc9d3fad2ff78e74e4f2d746b | |
| ToppCell | 390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells) | 1.20e-05 | 162 | 139 | 6 | fbb0cc2b1434a340dc35058b77c73ea61004c252 | |
| ToppCell | 356C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells) | 1.24e-05 | 163 | 139 | 6 | 2dbdcbc4c187aad3db837d191cc78662a75dd0b5 | |
| ToppCell | wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung | 1.58e-05 | 170 | 139 | 6 | fefb07a7e308b620f946b9ff2b01e1796446fe38 | |
| ToppCell | 3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5 | 2.11e-05 | 179 | 139 | 6 | 6bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9 | |
| ToppCell | Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor | 2.32e-05 | 182 | 139 | 6 | ed6ae0fd8653f213fe29906a6a4e0729a62e1b75 | |
| ToppCell | facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.47e-05 | 184 | 139 | 6 | 89ae8bf1a6c2d355d279d23a5e24a08d9ec2334e | |
| ToppCell | facs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.47e-05 | 184 | 139 | 6 | 34c84ac9a32eaf96f45b79485119cad65905817d | |
| ToppCell | CD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster | 3.04e-05 | 191 | 139 | 6 | 9454f642c3621370fa23640b631301346b300950 | |
| ToppCell | 368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells) | 3.13e-05 | 192 | 139 | 6 | efbd52b3d2b6d3fb9ed6bc3f36aca9f4f1fcbc49 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.32e-05 | 194 | 139 | 6 | bf34737ae2dc218f890fbb9201c308b324415749 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.32e-05 | 194 | 139 | 6 | b35e33439b6d3b5d69147e617224d2c8fd056223 | |
| ToppCell | facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.32e-05 | 194 | 139 | 6 | 4ebed7a6731b88c8359860072cbeba355a7e90ac | |
| ToppCell | droplet-Heart-HEART-1m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 3.52e-05 | 196 | 139 | 6 | 1eb14182ef26e6141f510d397b00bf8a12efda3e | |
| ToppCell | distal-Endothelial-Bronchial_Vessel_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 3.62e-05 | 197 | 139 | 6 | 9fcfbfbe78e8fe90c76eb37a58ed9dc8ece652a1 | |
| ToppCell | distal-3-Endothelial-Bronchial_Vessel_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed) | 3.72e-05 | 198 | 139 | 6 | f701d06e3d7fd2192afae3698c5ec3c355e96da3 | |
| ToppCell | Parenchymal-10x3prime_v2-Stromal-Myofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations | 3.83e-05 | 199 | 139 | 6 | 9a08c25bb4851ad4ac9db8916422280f71378c2c | |
| ToppCell | Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations | 3.83e-05 | 199 | 139 | 6 | 2ed10c5e15c9d5ed0a8bea580842348d5698a07b | |
| ToppCell | LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type | 3.93e-05 | 200 | 139 | 6 | 2dadf317a42a7e27cc1fac74f91b806c93a57108 | |
| Disease | Carcinoma, Transitional Cell | 1.01e-06 | 41 | 130 | 5 | C0007138 | |
| Disease | Precursor Cell Lymphoblastic Leukemia Lymphoma | 7.50e-06 | 61 | 130 | 5 | C1961102 | |
| Disease | RUBINSTEIN-TAYBI SYNDROME 1 | 1.93e-05 | 2 | 130 | 2 | 180849 | |
| Disease | Rubinstein-Taybi syndrome due to CREBBP mutations | 1.93e-05 | 2 | 130 | 2 | cv:C4551859 | |
| Disease | Menke-Hennekam syndrome | 1.93e-05 | 2 | 130 | 2 | cv:C5681632 | |
| Disease | Rubinstein-Taybi syndrome (implicated_via_orthology) | 1.93e-05 | 2 | 130 | 2 | DOID:1933 (implicated_via_orthology) | |
| Disease | Rubinstein-Taybi syndrome | 1.93e-05 | 2 | 130 | 2 | cv:C0035934 | |
| Disease | RUBINSTEIN-TAYBI SYNDROME 1 | 1.93e-05 | 2 | 130 | 2 | C4551859 | |
| Disease | Rubinstein-Taybi syndrome (is_implicated_in) | 1.93e-05 | 2 | 130 | 2 | DOID:1933 (is_implicated_in) | |
| Disease | tuberculin skin test reactivity measurement | 1.93e-05 | 2 | 130 | 2 | EFO_0008307 | |
| Disease | Rubinstein-Taybi Syndrome | 1.93e-05 | 2 | 130 | 2 | C0035934 | |
| Disease | Prostatic Neoplasms | ATP7B ARHGEF5 ESR2 IRS1 CREBBP FOXP4 ARID2 BRD4 KMT2A SPEN TP53 | 9.27e-05 | 616 | 130 | 11 | C0033578 |
| Disease | Malignant neoplasm of prostate | ATP7B ARHGEF5 ESR2 IRS1 CREBBP FOXP4 ARID2 BRD4 KMT2A SPEN TP53 | 9.27e-05 | 616 | 130 | 11 | C0376358 |
| Disease | Small cell carcinoma of lung | 9.59e-05 | 54 | 130 | 4 | C0149925 | |
| Disease | asthma, age at diagnosis | 1.15e-04 | 4 | 130 | 2 | EFO_0004918, MONDO_0004979 | |
| Disease | thiosulfate sulfurtransferase measurement | 2.86e-04 | 6 | 130 | 2 | EFO_0802130 | |
| Disease | acute lymphoblastic leukemia (implicated_via_orthology) | 2.86e-04 | 6 | 130 | 2 | DOID:9952 (implicated_via_orthology) | |
| Disease | Bladder Neoplasm | 3.98e-04 | 140 | 130 | 5 | C0005695 | |
| Disease | Nephronophthisis, familial juvenile | 3.99e-04 | 7 | 130 | 2 | C1855681 | |
| Disease | folding of antihelix | 3.99e-04 | 7 | 130 | 2 | EFO_0007671 | |
| Disease | Malignant neoplasm of urinary bladder | 4.12e-04 | 141 | 130 | 5 | C0005684 | |
| Disease | pulse pressure measurement | SHROOM3 NBEA ACAD10 CREB5 OPRL1 KIAA0753 PIK3R4 HIVEP3 KIAA1549L TET1 OSBPL7 ADAMTS15 KIF5B TP53 FILIP1L TBX2 | 4.22e-04 | 1392 | 130 | 16 | EFO_0005763 |
| Disease | Acute erythroleukemia - M6a subtype | 5.30e-04 | 8 | 130 | 2 | C2930975 | |
| Disease | Acute myeloid leukemia FAB-M6 | 5.30e-04 | 8 | 130 | 2 | C2930976 | |
| Disease | Acute erythroleukemia - M6b subtype | 5.30e-04 | 8 | 130 | 2 | C2930977 | |
| Disease | Acute erythroleukemia | 5.30e-04 | 8 | 130 | 2 | C2930974 | |
| Disease | Cornelia De Lange Syndrome | 5.30e-04 | 8 | 130 | 2 | C0270972 | |
| Disease | prostate carcinoma | SHROOM3 ESR2 POU2F2 WDPCP FOXP4 FMN1 KCNN3 TSHZ1 SPEN LRIF1 TP53 SOS1 | 5.92e-04 | 891 | 130 | 12 | EFO_0001663 |
| Disease | cup-to-disc ratio measurement | 6.59e-04 | 430 | 130 | 8 | EFO_0006939 | |
| Disease | spinal muscular atrophy (implicated_via_orthology) | 6.80e-04 | 9 | 130 | 2 | DOID:12377 (implicated_via_orthology) | |
| Disease | Malignant neoplasm of breast | TRERF1 ATP7B TICAM1 ESR2 SIK3 WNK1 ECT2 PIK3R4 FOXP4 PER2 SPEN EP300 TP53 | 9.40e-04 | 1074 | 130 | 13 | C0006142 |
| Disease | rheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement | 9.59e-04 | 170 | 130 | 5 | EFO_0000685, EFO_0007791, EFO_0007837 | |
| Disease | Malignant neoplasm of kidney | 1.04e-03 | 45 | 130 | 3 | C0740457 | |
| Disease | acute myeloid leukemia (implicated_via_orthology) | 1.24e-03 | 12 | 130 | 2 | DOID:9119 (implicated_via_orthology) | |
| Disease | atrial fibrillation | 1.32e-03 | 371 | 130 | 7 | EFO_0000275 | |
| Disease | fibrinogen measurement | 1.40e-03 | 109 | 130 | 4 | EFO_0004623 | |
| Disease | L2 Acute Lymphoblastic Leukemia | 1.41e-03 | 50 | 130 | 3 | C0023453 | |
| Disease | Benign tumor of pancreas | 1.46e-03 | 13 | 130 | 2 | C0347284 | |
| Disease | Squamous cell carcinoma of the head and neck | 1.58e-03 | 52 | 130 | 3 | C1168401 | |
| Disease | Childhood Acute Lymphoblastic Leukemia | 1.58e-03 | 52 | 130 | 3 | C0023452 | |
| Disease | level of Phosphatidylethanolamine (18:1_18:1) in blood serum | 1.69e-03 | 14 | 130 | 2 | OBA_2045142 | |
| Disease | Carcinoma, Granular Cell | 1.76e-03 | 116 | 130 | 4 | C0205644 | |
| Disease | Adenocarcinoma, Tubular | 1.76e-03 | 116 | 130 | 4 | C0205645 | |
| Disease | Adenocarcinoma, Oxyphilic | 1.76e-03 | 116 | 130 | 4 | C0205642 | |
| Disease | Carcinoma, Cribriform | 1.76e-03 | 116 | 130 | 4 | C0205643 | |
| Disease | Adenocarcinoma, Basal Cell | 1.76e-03 | 116 | 130 | 4 | C0205641 | |
| Disease | Adenocarcinoma | 1.76e-03 | 116 | 130 | 4 | C0001418 | |
| Disease | red blood cell density measurement | NRN1L SHROOM3 ESR2 ACAD10 SIK3 WNK1 ANKRD55 FMN1 ARID2 BRD4 OTUD4 | 1.81e-03 | 880 | 130 | 11 | EFO_0007978 |
| Disease | Diffuse Large B-Cell Lymphoma | 1.85e-03 | 55 | 130 | 3 | C0079744 | |
| Disease | colorectal cancer (is_implicated_in) | 2.05e-03 | 121 | 130 | 4 | DOID:9256 (is_implicated_in) | |
| Disease | T-Cell Lymphoma | 2.22e-03 | 16 | 130 | 2 | C0079772 | |
| Disease | cholesterol in medium HDL measurement | 2.27e-03 | 59 | 130 | 3 | EFO_0021903 | |
| Disease | triglycerides to total lipids in large HDL percentage | 2.38e-03 | 60 | 130 | 3 | EFO_0022330 | |
| Disease | cholesterol to total lipids in medium HDL percentage | 2.38e-03 | 60 | 130 | 3 | EFO_0022237 | |
| Disease | free cholesterol in HDL measurement | 2.50e-03 | 61 | 130 | 3 | EFO_0022264 | |
| Disease | response to vaccine, cytokine measurement | 2.74e-03 | 131 | 130 | 4 | EFO_0004645, EFO_0004873 | |
| Disease | attention deficit hyperactivity disorder, schizophrenia | 2.86e-03 | 64 | 130 | 3 | EFO_0003888, MONDO_0005090 | |
| Disease | mean reticulocyte volume | 2.89e-03 | 799 | 130 | 10 | EFO_0010701 | |
| Disease | osteochondrodysplasia (is_implicated_in) | 3.14e-03 | 19 | 130 | 2 | DOID:2256 (is_implicated_in) | |
| Disease | Pancreatic carcinoma | 3.14e-03 | 19 | 130 | 2 | C0235974 | |
| Disease | Dyschondroplasias | 3.14e-03 | 19 | 130 | 2 | C0013366 | |
| Disease | Neoplastic Cell Transformation | 3.39e-03 | 139 | 130 | 4 | C0007621 | |
| Disease | end stage renal disease (implicated_via_orthology) | 3.47e-03 | 20 | 130 | 2 | DOID:783 (implicated_via_orthology) | |
| Disease | insomnia measurement | 3.56e-03 | 443 | 130 | 7 | EFO_0007876 | |
| Disease | Precursor B-cell lymphoblastic leukemia | 3.83e-03 | 21 | 130 | 2 | C1292769 | |
| Disease | Colorectal Carcinoma | 3.99e-03 | 702 | 130 | 9 | C0009402 | |
| Disease | testosterone measurement | DCHS2 SHROOM3 ESR2 BIRC6 OPRL1 KIAA0753 CMIP NR0B1 DGKI MUCL3 ARHGAP21 TP53 SOS1 | 4.19e-03 | 1275 | 130 | 13 | EFO_0004908 |
| Disease | osteoporosis (biomarker_via_orthology) | 4.20e-03 | 22 | 130 | 2 | DOID:11476 (biomarker_via_orthology) | |
| Disease | cognitive function measurement | SYNDIG1L SZT2 NBEA TEF BIRC6 WDPCP PRR12 FMN1 NFIX ATF7IP PHLPP1 PRDM14 ARHGAP21 SOS1 | 4.38e-03 | 1434 | 130 | 14 | EFO_0008354 |
| Disease | schizophrenia, intelligence, self reported educational attainment | 4.40e-03 | 346 | 130 | 6 | EFO_0004337, EFO_0004784, MONDO_0005090 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| VPRQTPPLQHHGQLA | 726 | Q09472 | |
| PTGSGPLLHIPHRAI | 421 | Q8NEF3 | |
| ASHFLQPPPHQSIII | 1766 | Q9NR09 | |
| PHIKPLQNLSLHPGS | 71 | P54687 | |
| PHLQRHLPLATVSPG | 46 | Q13938 | |
| RSSQALSPHPQPTHL | 131 | P26842 | |
| GHFTQPILHLPQPEL | 821 | O60885 | |
| ELLCRAPSVPGVPHH | 1071 | Q86TB3 | |
| PHTGRLPANHAPDIL | 461 | P35670 | |
| ARVVVPTLKQHSHPP | 746 | Q12774 | |
| TLLHHPSVIPQQSPL | 761 | Q68CP9 | |
| RPLQSALHHVQPCPA | 241 | Q8NCL9 | |
| GHCPHPRVLPNLVAV | 316 | Q8IY22 | |
| HLHAGPVINTLPPIV | 1636 | Q92793 | |
| PHAPRHRQQSVLLVP | 846 | Q6JQN1 | |
| SVRPGHQEVSVPPHL | 521 | Q3KP44 | |
| VPPHLRHLHNPSSGQ | 531 | Q3KP44 | |
| GKPPHISSHPLLQDL | 881 | Q9Y4F5 | |
| HPKDPRGPSVLHNSV | 811 | Q8TE58 | |
| RHLPSVSSLPFHPQL | 586 | Q92617 | |
| LHPALIQRPFGIPAH | 106 | Q9BX46 | |
| ALPPRLQHPSGVRQH | 376 | Q01804 | |
| LPPHTQVHGSRLRLP | 2091 | P98160 | |
| RSPHRPLAGLHLSPV | 456 | Q96AA3 | |
| LLLLPGRPHPHGQSV | 366 | O75154 | |
| SPHGQTRPPASLKHI | 716 | Q9H8V3 | |
| PQQHHRILRLPALPG | 531 | Q68DA7 | |
| RHLPSVSSLPFHPQL | 506 | F8W0I5 | |
| HSAQIAKPIRPGQHP | 916 | P33176 | |
| PVTSPNKHLGLVTPH | 186 | Q01151 | |
| PVPGSLSSLLHLHNR | 156 | Q02930 | |
| HLRPQPPKTQVSSLH | 221 | Q5HY64 | |
| PIARRLGHHPPQSLN | 616 | Q6P3S6 | |
| LGHHPPQSLNVGKPL | 621 | Q6P3S6 | |
| RLHTLPPGLPRNVHV | 441 | Q7Z5L7 | |
| LAHTGGHQSPLPPLV | 951 | A5PL33 | |
| FTHHPLPVLAGVRPG | 346 | Q14938 | |
| SHRQAIPVLHSPTSP | 216 | Q13477 | |
| HSLPGRIVPPLQHNS | 131 | Q3KP22 | |
| PTPGHLSPLVVHRQL | 81 | Q92731 | |
| HSPPLNLPNNSHGIT | 71 | Q8N387 | |
| SPVLPSGHHLQIPAH | 176 | Q5T3J3 | |
| GEELLRIAPTPHHTP | 566 | P13196 | |
| RSSLSHLGPQHLPPG | 281 | Q86UW9 | |
| QPLSQRHPFLPHLGL | 221 | O95208 | |
| VQVPPRIHPTATHHI | 971 | Q8NDA2 | |
| PLPLSQRTLLHGSGH | 3361 | Q8NDA2 | |
| LPHHSSTQPLDLAPG | 211 | P0C7T5 | |
| LHQVTPVFRHPPCSN | 711 | Q99665 | |
| PSLQSLHPVSPSHQR | 1046 | Q5VZ46 | |
| QAPVSRPVLTLHHGP | 201 | Q6DN72 | |
| RPVLTLHHGPADPAV | 206 | Q6DN72 | |
| IHRLLLQPVPHSGSS | 466 | O15055 | |
| RHNAGSNPTPPTLLI | 796 | Q96RV3 | |
| LQSQPVHPGLLHSSP | 91 | Q9UGI6 | |
| PGQLHPHLTVAKVPH | 441 | Q96B70 | |
| FGRHIPPCIHIPLAN | 266 | Q8NGK2 | |
| QLVLVPGHHLQPPAQ | 111 | P09086 | |
| PPGNHSLSLEAPRLH | 6 | Q86UT5 | |
| PPIGHITVHPATLNH | 486 | Q99583 | |
| RHLPSVSSLPFHPQL | 711 | A8MRT5 | |
| PLSHHTLPNGQPTVL | 271 | Q8IVH2 | |
| PTTRHSVSHPQLQLP | 526 | Q6ZVL6 | |
| FPPGTLLAPRHHVTV | 406 | Q8IXW0 | |
| HHELPPGSTKRALPN | 296 | P04637 | |
| VLPSIHQLHPASPRG | 476 | O94927 | |
| RHHLNNPPPSQVGLT | 286 | P35568 | |
| RHLPSVSSLPFHPQL | 716 | C9JG80 | |
| VLVPTRHPHAIPGSI | 531 | Q96M63 | |
| TQPHPHATVIPDRTL | 461 | Q68CR7 | |
| HGTPRALLHPLLQDP | 156 | O75161 | |
| VQLGPQSTHHSPRTP | 851 | Q9Y2X0 | |
| TQAHPLGPQRAASPL | 1106 | Q6V1P9 | |
| VPTLQHHLAPPAEAR | 336 | P51843 | |
| RHLPSVSSLPFHPQL | 726 | E5RHQ5 | |
| HRRQLGPQGPPHLVA | 56 | P01350 | |
| LPPSCPTHRHILQQR | 671 | O95876 | |
| LTLGPTCPHHVPVQV | 521 | O00341 | |
| HTPGQPLHIKVTPDH | 896 | Q4L180 | |
| GLQHLAPAHPLSLPV | 141 | O75912 | |
| ARAGLPSTHLHVPTP | 131 | Q9NPZ5 | |
| RLETHVPSPGLTHPA | 356 | Q8N1P7 | |
| PATPVTLGQHHLPVR | 606 | P85037 | |
| TGPQLTVHHRPPQVH | 1116 | Q6VMQ6 | |
| HPPPHLKTQLEINGR | 71 | Q9NUK0 | |
| NPSNLHFLSTLPRPH | 306 | O60336 | |
| TPVPPSAGHLAHVRE | 176 | Q63ZY3 | |
| PPLNPHGSARAEVHL | 3756 | Q03164 | |
| RQPQPVHLLPLHGIQ | 386 | P04180 | |
| PALTVHPAHQLGASP | 126 | Q04741 | |
| HPGPVNSELFLRHVP | 226 | Q6UX07 | |
| DHIVLHSGQRPPELP | 61 | Q3MIW9 | |
| RHLPSVSSLPFHPQL | 716 | A6NJU9 | |
| HELHGAQLSLRPAPP | 71 | Q53GL7 | |
| LHRIPSAPVIPTHQA | 221 | Q9BZF2 | |
| TLGPGLQPLPQTSHH | 86 | P51460 | |
| NLSLLSPNHSLLPPH | 21 | P41146 | |
| PRPNNLHTLCGAPVH | 106 | Q496H8 | |
| RAPLGAPNPFHLQLH | 136 | O60391 | |
| TRFPPEPNGILHIGH | 266 | P47897 | |
| ELQNPLLPRSPAHLH | 6 | A6NDD5 | |
| HPGLSNLATPHRLAI | 1676 | Q5T011 | |
| QASTLLAQGPRPHAP | 871 | Q7Z5M5 | |
| PASLHHAISGLLVPP | 216 | Q9GZV8 | |
| VVVIPSIPHPSLNHG | 1611 | Q8NFP9 | |
| QSLPTAHVRPSHPLK | 1346 | Q92859 | |
| GPRLHQGHATLPTEP | 66 | A0A1B0GW64 | |
| ALLHEGPESPHRPSL | 281 | Q92835 | |
| PHILQGLLSPRHSLT | 966 | Q9Y2K2 | |
| LKRHLTPPQGNSPHS | 571 | Q8TF72 | |
| PASPTHLAHNLLLPV | 111 | Q10587 | |
| PGLQPHPRIGDHKNI | 196 | Q2KHM9 | |
| SPPANGLLSPHDVLH | 176 | Q9ULL5 | |
| RHLPSPPLTQEVDLH | 1271 | Q07889 | |
| GRNHLVLRLHPAPCP | 156 | Q92935 | |
| SRPELHPVQPLALHV | 121 | O94993 | |
| HQRLPTLPGISHETP | 1331 | Q8NFU7 | |
| SPTGPHPLEHLLARL | 16 | Q8NBR9 | |
| PLSELQPSPHSVHGI | 1231 | Q99570 | |
| PPHQVLVVPLHSRIS | 81 | Q2NL82 | |
| ANLGSTLTPHHPPAL | 2976 | Q96T58 | |
| THLASTAAPIPQHLP | 711 | Q6ZNA4 | |
| ISHHIPATAPPAQRL | 731 | Q6ZNA4 | |
| GPHPPAAHLRSLKSL | 81 | Q13207 | |
| RLLPTATTNGHPQLP | 521 | Q03431 | |
| PQSPGLQPLIIHHAQ | 671 | Q8IUC6 | |
| HAVIPTQLPSRPGHR | 26 | Q8WWF5 | |
| PGLHPQSQLLPSHAS | 136 | Q5T1R4 | |
| PLHSQHLTRAPCPLI | 2181 | Q5T1R4 | |
| QASVPPHQLRLGSLH | 286 | P30530 | |
| HAQLLEQHRGQPLPP | 846 | P27708 | |
| TPGLLHPQTSPLLHS | 1906 | P27708 | |
| LTHPSHRLPQQGEKP | 281 | Q8N393 | |
| AHRPLAGAVAHPQPL | 136 | P31314 | |
| HQRIHIGESLSPPNP | 516 | Q96NI8 | |
| FLHPSVVPRPHVQSV | 1346 | O60346 | |
| QHIVRTDLHVQGPPP | 386 | Q9UL62 | |
| LPQRHNSLHRKTPGP | 276 | Q8TF74 | |
| SAASVLHPQQTLHPP | 2156 | Q9H4A3 | |
| VLHCHVSTRVGPPNP | 166 | Q9BVT8 | |
| LLHLRASGQPHPTPE | 21 | P0DP72 | |
| PLSIPTTHLIHQPAG | 321 | Q5T5U3 | |
| LIGQQLQPLSHHAPP | 121 | Q04725 | |
| EHNALLHSPGSLTPP | 616 | Q6ZSZ6 | |
| KLGTQPSLPHVRQPH | 126 | Q8TEY7 | |
| VHPSPNLILSQKRPH | 176 | P51508 | |
| STLPHRPLLSPSGIH | 446 | Q96PN7 |