Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intracellular sodium-activated potassium channel activity	KCNT2 KCNT1	1.47e-05	2	77	2	GO:0005228
GeneOntologyMolecularFunction	phorbol ester receptor activity	UNC13B UNC13C	1.47e-05	2	77	2	GO:0001565
GeneOntologyMolecularFunction	non-kinase phorbol ester receptor activity	UNC13B UNC13C	1.47e-05	2	77	2	GO:0001566
GeneOntologyMolecularFunction	diacylglycerol binding	UNC13B UNC13C UNC13A	2.98e-05	16	77	3	GO:0019992
GeneOntologyMolecularFunction	syntaxin-1 binding	UNC13B UNC13C UNC13A	1.05e-04	24	77	3	GO:0017075
GeneOntologyMolecularFunction	RNA polymerase binding	AGO2 AGO1 BRCA1 SCAF4	1.16e-04	65	77	4	GO:0070063
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKFB4 PFKM	3.04e-04	7	77	2	GO:0008443
GeneOntologyMolecularFunction	RNA polymerase II complex binding	AGO2 AGO1 SCAF4	4.56e-04	39	77	3	GO:0000993
GeneOntologyMolecularFunction	RNA polymerase core enzyme binding	AGO2 AGO1 SCAF4	6.96e-04	45	77	3	GO:0043175
GeneOntologyMolecularFunction	core promoter sequence-specific DNA binding	AGO2 AGO1 FOXP1	1.25e-03	55	77	3	GO:0001046
GeneOntologyBiologicalProcess	dense core granule priming	UNC13B UNC13C UNC13A	2.08e-07	4	78	3	GO:0061789
GeneOntologyBiologicalProcess	dense core granule localization	UNC13B TANC2 UNC13C UNC13A	3.62e-06	28	78	4	GO:0032253
GeneOntologyBiologicalProcess	presynaptic dense core vesicle exocytosis	UNC13B UNC13C UNC13A	6.12e-06	10	78	3	GO:0099525
GeneOntologyBiologicalProcess	secretory granule localization	UNC13B TANC2 UNC13C UNC13A	8.05e-06	34	78	4	GO:0032252
GeneOntologyBiologicalProcess	neuronal dense core vesicle exocytosis	UNC13B UNC13C UNC13A	1.12e-05	12	78	3	GO:0099011
GeneOntologyBiologicalProcess	dense core granule docking	UNC13B UNC13A	1.41e-05	2	78	2	GO:0061790
GeneOntologyBiologicalProcess	dense core granule exocytosis	UNC13B UNC13C UNC13A	2.29e-05	15	78	3	GO:1990504
GeneOntologyBiologicalProcess	synaptic vesicle docking	UNC13B UNC13C UNC13A	3.41e-05	17	78	3	GO:0016081
GeneOntologyBiologicalProcess	innate vocalization behavior	FOXP2 FOXP1	4.23e-05	3	78	2	GO:0098582
GeneOntologyBiologicalProcess	siRNA-mediated post-transcriptional gene silencing	AGO2 AGO1	8.43e-05	4	78	2	GO:0140766
GeneOntologyBiologicalProcess	siRNA-mediated gene silencing by mRNA destabilization	AGO2 AGO1	8.43e-05	4	78	2	GO:0090625
GeneOntologyBiologicalProcess	calcium ion-regulated exocytosis of neurotransmitter	UNC13B UNC13C UNC13A	1.13e-04	25	78	3	GO:0048791
GeneOntologyBiologicalProcess	positive regulation of glutamate receptor signaling pathway	NECAB2 UNC13A	1.40e-04	5	78	2	GO:1900451
GeneOntologyBiologicalProcess	negative regulation of synaptic plasticity	UNC13B UNC13C	2.10e-04	6	78	2	GO:0031914
GeneOntologyBiologicalProcess	vesicle-mediated transport in synapse	UNC13B SLC32A1 ATP6V1G2 STON2 UNC13C GRIP2 UNC13A	2.13e-04	321	78	7	GO:0099003
GeneOntologyBiologicalProcess	synaptic vesicle priming	UNC13B UNC13C UNC13A	2.17e-04	31	78	3	GO:0016082
GeneOntologyBiologicalProcess	regulation of glutamate receptor signaling pathway	NECAB2 UNC13A	3.90e-04	8	78	2	GO:1900449
GeneOntologyCellularComponent	synaptic vesicle	UNC13B SLC32A1 ATP6V1G2 CYP19A1 STON2 UNC13C DMD UNC13A	1.77e-05	300	79	8	GO:0008021
GeneOntologyCellularComponent	exocytic vesicle	UNC13B SLC32A1 ATP6V1G2 CYP19A1 STON2 UNC13C DMD UNC13A	2.81e-05	320	79	8	GO:0070382
GeneOntologyCellularComponent	exocytic vesicle membrane	UNC13B SLC32A1 ATP6V1G2 UNC13C DMD UNC13A	6.00e-05	179	79	6	GO:0099501
GeneOntologyCellularComponent	synaptic vesicle membrane	UNC13B SLC32A1 ATP6V1G2 UNC13C DMD UNC13A	6.00e-05	179	79	6	GO:0030672
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	UNC13B UNC13C UNC13A	8.71e-05	23	79	3	GO:0098831
GeneOntologyCellularComponent	neuron projection terminus	UNC13B SLC32A1 CYP19A1 UNC13C DMD UNC13A	2.54e-04	233	79	6	GO:0044306
GeneOntologyCellularComponent	calyx of Held	UNC13B UNC13C UNC13A	3.39e-04	36	79	3	GO:0044305
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	UNC13B ZFYVE28 SLC32A1 WDR91 STK10 ATP6V1G2 ROR2 TOM1 STON2 TAB2 UNC13C DMD CCDC136 UNC13A	3.52e-04	1307	79	14	GO:0030659
GeneOntologyCellularComponent	vesicle membrane	UNC13B ZFYVE28 SLC32A1 WDR91 STK10 ATP6V1G2 ROR2 TOM1 STON2 TAB2 UNC13C DMD CCDC136 UNC13A	4.04e-04	1325	79	14	GO:0012506
GeneOntologyCellularComponent	terminal bouton	UNC13B CYP19A1 UNC13C UNC13A	4.82e-04	96	79	4	GO:0043195
GeneOntologyCellularComponent	inner dynein arm	DNHD1 DNAH10	6.22e-04	10	79	2	GO:0036156
GeneOntologyCellularComponent	RISC-loading complex	AGO2 AGO1	6.22e-04	10	79	2	GO:0070578
GeneOntologyCellularComponent	cell cortex region	UNC13B UNC13C UNC13A	6.58e-04	45	79	3	GO:0099738
GeneOntologyCellularComponent	transport vesicle	UNC13B SLC32A1 ATP6V1G2 CYP19A1 STON2 UNC13C DMD UNC13A	7.61e-04	519	79	8	GO:0030133
GeneOntologyCellularComponent	transport vesicle membrane	UNC13B SLC32A1 ATP6V1G2 UNC13C DMD UNC13A	8.50e-04	293	79	6	GO:0030658
GeneOntologyCellularComponent	axon terminus	UNC13B SLC32A1 CYP19A1 UNC13C UNC13A	1.20e-03	210	79	5	GO:0043679
GeneOntologyCellularComponent	presynaptic active zone	UNC13B SLC32A1 UNC13C UNC13A	2.01e-03	141	79	4	GO:0048786
GeneOntologyCellularComponent	clathrin-coated vesicle membrane	SLC32A1 ATP6V1G2 ROR2 STON2	2.34e-03	147	79	4	GO:0030665
GeneOntologyCellularComponent	secretory vesicle	UNC13B SLC32A1 STK10 ATP6V1G2 CYP19A1 TOM1 STON2 UNC13C DMD DNAJC3 CCDC136 UNC13A	2.40e-03	1246	79	12	GO:0099503
GeneOntologyCellularComponent	cytoplasmic region	UNC13B DNHD1 DNAH10 WDR35 UNC13C UNC13A	2.42e-03	360	79	6	GO:0099568
Domain	Unc-13	UNC13B UNC13C UNC13A	7.01e-08	3	78	3	IPR027080
Domain	-	CEP104 STK36 NCAPD3 HEATR6 IPO7 ANKAR RANBP6 TTI1 HEATR1	3.61e-07	222	78	9	1.25.10.10
Domain	Munc13_dom-2	UNC13B UNC13C UNC13A	6.97e-07	5	78	3	IPR014772
Domain	Membr_traf_MHD	UNC13B UNC13C UNC13A	6.97e-07	5	78	3	PF10540
Domain	MHD2	UNC13B UNC13C UNC13A	6.97e-07	5	78	3	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13C UNC13A	6.97e-07	5	78	3	IPR019558
Domain	DUF1041	UNC13B UNC13C UNC13A	6.97e-07	5	78	3	SM01145
Domain	ARM-type_fold	CEP104 STK36 NCAPD3 HEATR6 ZBTB7C IPO7 ANKAR RANBP6 TTI1 HEATR1	1.43e-06	339	78	10	IPR016024
Domain	HEAT	CEP104 STK36 NCAPD3 RANBP6 HEATR1	1.66e-06	48	78	5	PF02985
Domain	ARM-like	CEP104 STK36 NCAPD3 HEATR6 IPO7 ANKAR RANBP6 TTI1 HEATR1	1.84e-06	270	78	9	IPR011989
Domain	DUF1041	UNC13B UNC13C UNC13A	2.42e-06	7	78	3	PF06292
Domain	Munc13_1	UNC13B UNC13C UNC13A	2.42e-06	7	78	3	IPR014770
Domain	CAPS_dom	UNC13B UNC13C UNC13A	2.42e-06	7	78	3	IPR010439
Domain	MHD1	UNC13B UNC13C UNC13A	2.42e-06	7	78	3	PS51258
Domain	HEAT	CEP104 STK36 NCAPD3 RANBP6 HEATR1	4.30e-06	58	78	5	IPR000357
Domain	HEAT_REPEAT	CEP104 NCAPD3 HEATR6 RANBP6 HEATR1	1.09e-05	70	78	5	PS50077
Domain	C1_1	UNC13B UNC13C CHN2 UNC13A	9.40e-05	57	78	4	PF00130
Domain	FOXP-CC	FOXP2 FOXP1	1.03e-04	4	78	2	PF16159
Domain	FOXP-CC	FOXP2 FOXP1	1.03e-04	4	78	2	IPR032354
Domain	Argonaute_N	AGO2 AGO1	1.03e-04	4	78	2	IPR032474
Domain	Argonaute_Mid_dom	AGO2 AGO1	1.03e-04	4	78	2	IPR032473
Domain	ArgoL2	AGO2 AGO1	1.03e-04	4	78	2	IPR032472
Domain	K_chnl_Ca-activ_BK_asu	KCNT2 KCNT1	1.03e-04	4	78	2	IPR003929
Domain	ArgoN	AGO2 AGO1	1.03e-04	4	78	2	PF16486
Domain	ArgoMid	AGO2 AGO1	1.03e-04	4	78	2	PF16487
Domain	ArgoL2	AGO2 AGO1	1.03e-04	4	78	2	PF16488
Domain	BK_channel_a	KCNT2 KCNT1	1.03e-04	4	78	2	PF03493
Domain	ZF_DAG_PE_1	UNC13B UNC13C CHN2 UNC13A	1.48e-04	64	78	4	PS00479
Domain	ZF_DAG_PE_2	UNC13B UNC13C CHN2 UNC13A	1.48e-04	64	78	4	PS50081
Domain	C1	UNC13B UNC13C CHN2 UNC13A	1.57e-04	65	78	4	SM00109
Domain	PE/DAG-bd	UNC13B UNC13C CHN2 UNC13A	1.67e-04	66	78	4	IPR002219
Domain	DUF1785	AGO2 AGO1	1.71e-04	5	78	2	SM01163
Domain	P-loop_NTPase	TANC2 DNHD1 ORC5 TRANK1 MDN1 DNAH10 GUK1 ABCD1 DHX33 GAL3ST2 PFKFB4 DDX39A	1.95e-04	848	78	12	IPR027417
Domain	ENTH_VHS	TOM1 TTI1 SCAF4	2.37e-04	29	78	3	IPR008942
Domain	ArgoL1	AGO2 AGO1	2.55e-04	6	78	2	PF08699
Domain	ArgoL1	AGO2 AGO1	2.55e-04	6	78	2	IPR014811
Domain	PIWI	AGO2 AGO1	4.74e-04	8	78	2	PS50822
Domain	Piwi	AGO2 AGO1	4.74e-04	8	78	2	SM00950
Domain	Piwi	AGO2 AGO1	4.74e-04	8	78	2	IPR003165
Domain	Piwi	AGO2 AGO1	4.74e-04	8	78	2	PF02171
Domain	PAZ	AGO2 AGO1	6.08e-04	9	78	2	PS50821
Domain	PAZ	AGO2 AGO1	6.08e-04	9	78	2	SM00949
Domain	PAZ_dom	AGO2 AGO1	6.08e-04	9	78	2	IPR003100
Domain	PAZ	AGO2 AGO1	6.08e-04	9	78	2	PF02170
Domain	-	DNHD1 ORC5 TRANK1 MDN1 DNAH10 GUK1 ABCD1 DHX33 PFKFB4 DDX39A	1.05e-03	746	78	10	3.40.50.300
Domain	FH	FOXP2 FOXP1 FOXR2	1.12e-03	49	78	3	SM00339
Domain	FORK_HEAD_1	FOXP2 FOXP1 FOXR2	1.12e-03	49	78	3	PS00657
Domain	FORK_HEAD_2	FOXP2 FOXP1 FOXR2	1.12e-03	49	78	3	PS00658
Domain	Fork_head_dom	FOXP2 FOXP1 FOXR2	1.12e-03	49	78	3	IPR001766
Domain	FORK_HEAD_3	FOXP2 FOXP1 FOXR2	1.12e-03	49	78	3	PS50039
Domain	Forkhead	FOXP2 FOXP1 FOXR2	1.12e-03	49	78	3	PF00250
Domain	Dynein_HC_stalk	DNHD1 DNAH10	1.52e-03	14	78	2	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH10	1.52e-03	14	78	2	IPR013602
Domain	DHC_N2	DNHD1 DNAH10	1.52e-03	14	78	2	PF08393
Domain	MT	DNHD1 DNAH10	1.52e-03	14	78	2	PF12777
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH10	1.52e-03	14	78	2	IPR011704
Domain	AAA_5	MDN1 DNAH10	1.52e-03	14	78	2	PF07728
Domain	DHC_fam	DNHD1 DNAH10	1.75e-03	15	78	2	IPR026983
Domain	Dynein_heavy_dom	DNHD1 DNAH10	1.75e-03	15	78	2	IPR004273
Domain	Dynein_heavy	DNHD1 DNAH10	1.75e-03	15	78	2	PF03028
Domain	RmlC_Cupin	HGD FOXP2	1.99e-03	16	78	2	IPR011051
Domain	TPR-like_helical_dom	TANC2 TRANK1 USP28 WDR35 DNAJC3	2.92e-03	233	78	5	IPR011990
Domain	RNaseH-like_dom	AGO2 AGO1 PRPF8	3.01e-03	69	78	3	IPR012337
Domain	-	UNC13B UNC13C SEC63 UNC13A	3.43e-03	148	78	4	2.60.40.150
Domain	K_chnl_dom	KCNT2 KCNT1	3.43e-03	21	78	2	IPR013099
Domain	Ion_trans_2	KCNT2 KCNT1	3.43e-03	21	78	2	PF07885
Domain	zf-RanBP	TAB2 RBCK1	3.77e-03	22	78	2	PF00641
Domain	ZnF_RBZ	TAB2 RBCK1	4.12e-03	23	78	2	SM00547
Domain	ZF_RANBP2_2	TAB2 RBCK1	4.12e-03	23	78	2	PS50199
Pathway	WP_SYNAPTIC_VESICLE_PATHWAY	UNC13B SLC32A1 UNC13C UNC13A	5.58e-05	51	58	4	M39457
Pathway	BIOCARTA_DICER_PATHWAY	AGO2 AGO1	1.65e-04	5	58	2	M22079
Pathway	REACTOME_MICRORNA_MIRNA_BIOGENESIS	AGO2 AGO1	2.47e-04	6	58	2	MM14818
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	AGO2 AGO1	2.47e-04	6	58	2	MM15083
Pathway	REACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	ADAM19 AGO2 AGO1	3.01e-04	32	58	3	M48012
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	AGO2 AGO1	3.45e-04	7	58	2	M46421
Pathway	REACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS	AGO2 AGO1	4.58e-04	8	58	2	MM15082
Pathway	REACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS	AGO2 AGO1	5.88e-04	9	58	2	M27340
Pathway	REACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION	AGO2 AGO1	5.88e-04	9	58	2	M27810
Pathway	REACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION	AGO2 AGO1	5.88e-04	9	58	2	M46436
Pathway	REACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS	AGO2 AGO1	7.33e-04	10	58	2	M48013
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13C UNC13A	1.17e-08	3	80	3	33105896
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13C UNC13A	1.17e-08	3	80	3	23658173
Pubmed	Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.	UNC13B UNC13C UNC13A	1.17e-08	3	80	3	22966208
Pubmed	Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.	UNC13B UNC13C UNC13A	1.17e-08	3	80	3	15988013
Pubmed	An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.	UNC13B UNC13C UNC13A	1.17e-07	5	80	3	34706221
Pubmed	Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.	UNC13B UNC13C UNC13A	1.17e-07	5	80	3	26575293
Pubmed	Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.	UNC13B UNC13C UNC13A	4.07e-07	7	80	3	36398873
Pubmed	Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.	UNC13B UNC13C UNC13A	6.51e-07	8	80	3	25609709
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	STK36 AGO2 IPO7 KPRP GRIP2 HEATR1 ABCD1 DMD SEC63 PRPF8 DDX39A	1.25e-06	754	80	11	35906200
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	UNC13B UNC13C UNC13A	1.91e-06	11	80	3	34767769
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ORC5 NCAPD3 MDN1 FOXP2 USP28 FOXP1 HEATR1 PRPF8 DDX39A FOXR2 NOTCH3	4.25e-06	857	80	11	25609649
Pubmed	Cell volume changes regulate slick (Slo2.1), but not slack (Slo2.2) K+ channels.	KCNT2 KCNT1	5.23e-06	2	80	2	25347289
Pubmed	Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the Striatum of Adult Mouse Brain.	FOXP2 FOXP1	5.23e-06	2	80	2	30031127
Pubmed	Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors.	AGO2 AGO1	5.23e-06	2	80	2	26242502
Pubmed	Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion.	FOXP2 FOXP1	5.23e-06	2	80	2	30104377
Pubmed	Regulation of insulin exocytosis by Munc13-1.	UNC13B UNC13A	5.23e-06	2	80	2	12871971
Pubmed	Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.	UNC13B UNC13A	5.23e-06	2	80	2	17561838
Pubmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.	UNC13B UNC13A	5.23e-06	2	80	2	28489077
Pubmed	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.	UNC13B UNC13A	5.23e-06	2	80	2	10440375
Pubmed	Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.	UNC13B UNC13A	5.23e-06	2	80	2	22066784
Pubmed	Notch3 null mutation in mice causes muscle hyperplasia by repetitive muscle regeneration.	DMD NOTCH3	5.23e-06	2	80	2	20960513
Pubmed	Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.	UNC13B UNC13A	5.23e-06	2	80	2	32187536
Pubmed	Slack and Slick K(Na) channels regulate the accuracy of timing of auditory neurons.	KCNT2 KCNT1	5.23e-06	2	80	2	17344399
Pubmed	Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.	UNC13B UNC13A	5.23e-06	2	80	2	22814762
Pubmed	Involvement of AGO1 and AGO2 in mammalian transcriptional silencing.	AGO2 AGO1	5.23e-06	2	80	2	16936728
Pubmed	Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.	UNC13B UNC13A	5.23e-06	2	80	2	28426965
Pubmed	Human eukaryotic initiation factor EIF2C1 gene: cDNA sequence, genomic organization, localization to chromosomal bands 1p34-p35, and expression.	AGO2 AGO1	5.23e-06	2	80	2	10534406
Pubmed	Argonaute Family Protein Expression in Normal Tissue and Cancer Entities.	AGO2 AGO1	5.23e-06	2	80	2	27518285
Pubmed	Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.	UNC13B UNC13A	5.23e-06	2	80	2	23770256
Pubmed	Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.	UNC13B UNC13C	5.23e-06	2	80	2	22674279
Pubmed	Investigating protein-protein interactions in live cells using bioluminescence resonance energy transfer.	FOXP2 FOXP1	5.23e-06	2	80	2	24893771
Pubmed	Association of Polymorphic Variants in Argonaute Genes with Depression Risk in a Polish Population.	AGO2 AGO1	5.23e-06	2	80	2	36142498
Pubmed	Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.	UNC13B UNC13A	5.23e-06	2	80	2	31851910
Pubmed	Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction.	FOXP2 FOXP1	5.23e-06	2	80	2	15056695
Pubmed	A de novo FOXP1 variant in a patient with autism, intellectual disability and severe speech and language impairment.	FOXP2 FOXP1	5.23e-06	2	80	2	25853299
Pubmed	FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures.	FOXP2 FOXP1	5.23e-06	2	80	2	27224915
Pubmed	Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors.	FOXP2 FOXP1	5.23e-06	2	80	2	11358962
Pubmed	Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.	UNC13B UNC13A	5.23e-06	2	80	2	11832228
Pubmed	Equivalent missense variant in the FOXP2 and FOXP1 transcription factors causes distinct neurodevelopmental disorders.	FOXP2 FOXP1	5.23e-06	2	80	2	28741757
Pubmed	Polymorphisms and expression of genes encoding Argonautes 1 and 2 in autoimmune thyroid diseases.	AGO2 AGO1	5.23e-06	2	80	2	29256262
Pubmed	Munc13 controls the location and efficiency of dense-core vesicle release in neurons.	UNC13B UNC13A	5.23e-06	2	80	2	23229896
Pubmed	Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning.	KCNT2 KCNT1	5.23e-06	2	80	2	26845140
Pubmed	Argonaute proteins couple chromatin silencing to alternative splicing.	AGO2 AGO1	5.23e-06	2	80	2	22961379
Pubmed	Molecular mechanisms of Slo2 K+ channel closure.	KCNT2 KCNT1	5.23e-06	2	80	2	27682982
Pubmed	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.	UNC13B UNC13A	5.23e-06	2	80	2	12070347
Pubmed	Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.	UNC13B UNC13A	5.23e-06	2	80	2	23070049
Pubmed	Aromatase expression is increased in BRCA1 mutation carriers.	BRCA1 CYP19A1	5.23e-06	2	80	2	19445691
Pubmed	Association study of AGO1 and AGO2 genes polymorphisms with recurrent pregnancy loss.	AGO2 AGO1	5.23e-06	2	80	2	31666609
Pubmed	Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.	UNC13B UNC13A	5.23e-06	2	80	2	28772123
Pubmed	Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.	UNC13B UNC13A	5.23e-06	2	80	2	17267576
Pubmed	Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins.	AGO2 AGO1	5.23e-06	2	80	2	23019594
Pubmed	BRCA1 breast cancer risk is modified by CYP19 polymorphisms in Ashkenazi Jews.	BRCA1 CYP19A1	5.23e-06	2	80	2	19366906
Pubmed	Differential distribution of the sodium-activated potassium channels slick and slack in mouse brain.	KCNT2 KCNT1	5.23e-06	2	80	2	26587966
Pubmed	A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.	UNC13B UNC13A	5.23e-06	2	80	2	35613050
Pubmed	Membrane bridging by Munc13-1 is crucial for neurotransmitter release.	UNC13B UNC13A	5.23e-06	2	80	2	30816091
Pubmed	A common molecular basis for membrane docking and functional priming of synaptic vesicles.	UNC13B UNC13A	5.23e-06	2	80	2	19558619
Pubmed	Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.	UNC13B UNC13A	5.23e-06	2	80	2	18701688
Pubmed	Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice.	KCNT2 KCNT1	5.23e-06	2	80	2	30796290
Pubmed	Distinct AGO1 and AGO2 associated miRNA profiles in human cells and blood plasma.	AGO2 AGO1	5.23e-06	2	80	2	22858679
Pubmed	Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.	AGO2 AGO1	5.23e-06	2	80	2	12230974
Pubmed	Compensation between FOXP transcription factors maintains proper striatal function.	FOXP2 FOXP1	5.23e-06	2	80	2	38761373
Pubmed	Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.	UNC13B UNC13A	5.23e-06	2	80	2	11792326
Pubmed	mRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer.	AGO2 AGO1	5.23e-06	2	80	2	19723326
Pubmed	Evaluation of Argonaute protein as a predictive marker for human clear cell renal cell carcinoma.	AGO2 AGO1	5.23e-06	2	80	2	23696926
Pubmed	Ago1 and Ago2 differentially affect cell proliferation, motility and apoptosis when overexpressed in SH-SY5Y neuroblastoma cells.	AGO2 AGO1	5.23e-06	2	80	2	21846468
Pubmed	The association of AGO1 (rs595961G>A, rs636832A>G) and AGO2 (rs11996715C>A, rs2292779C>G, rs4961280C>A) polymorphisms and risk of recurrent implantation failure.	AGO2 AGO1	5.23e-06	2	80	2	31724726
Pubmed	Identification and functional characterization of de novo FOXP1 variants provides novel insights into the etiology of neurodevelopmental disorder.	FOXP2 FOXP1	5.23e-06	2	80	2	26647308
Pubmed	Identification of potential protein interactors of Lrrk2.	AGO2 AGO1 MDN1	5.23e-06	15	80	3	17400507
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	TANC2 ORC5 MDN1 ZBTB7C IPO7 CCT3 PFKM PRPF8 DDX39A	7.81e-06	582	80	9	20467437
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	NCAPD3 MDN1 CCT3 TTI1 PFKM PRPF8 DDX39A	1.19e-05	332	80	7	32786267
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	MDN1 CCT3 PRPF8 LRCH1 NOTCH3	1.25e-05	129	80	5	23022380
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TANC2 WDR91 AGO2 AGO1 MDN1 CCT3 FOXP2 USP28 STON2 KCNT1 UNC13A	1.27e-05	963	80	11	28671696
Pubmed	Turning catalytically inactive human Argonaute proteins into active slicer enzymes.	AGO2 AGO1	1.57e-05	3	80	2	23665583
Pubmed	Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues.	FOXP2 FOXP1	1.57e-05	3	80	2	14516685
Pubmed	The roles of individual mammalian argonautes in RNA interference in vivo.	AGO2 AGO1	1.57e-05	3	80	2	24992693
Pubmed	Human-specific transcriptional regulation of CNS development genes by FOXP2.	FOXP2 FOXP1	1.57e-05	3	80	2	19907493
Pubmed	miR-206 enforces a slow muscle phenotype.	CYP19A1 DMD	1.57e-05	3	80	2	32620696
Pubmed	Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells.	AGO2 AGO1	1.57e-05	3	80	2	24086155
Pubmed	Transcriptional regulation by FOXP1, FOXP2, and FOXP4 dimerization.	FOXP2 FOXP1	1.57e-05	3	80	2	25027557
Pubmed	Argonaute2 is the catalytic engine of mammalian RNAi.	AGO2 AGO1	1.57e-05	3	80	2	15284456
Pubmed	Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.	AGO2 AGO1	1.57e-05	3	80	2	19946268
Pubmed	Hepatic Ago2-mediated RNA silencing controls energy metabolism linked to AMPK activation and obesity-associated pathophysiology.	AGO2 AGO1	1.57e-05	3	80	2	30201950
Pubmed	Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming.	UNC13B UNC13A	1.57e-05	3	80	2	37343100
Pubmed	A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway.	AGO2 AGO1	1.57e-05	3	80	2	17626790
Pubmed	Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neurons.	KCNT2 KCNT1	1.57e-05	3	80	2	26559620
Pubmed	Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies.	AGO2 AGO1	1.57e-05	3	80	2	15908945
Pubmed	Protein-Protein Interaction Among the FoxP Family Members and their Regulation of Two Target Genes, VLDLR and CNTNAP2 in the Zebra Finch Song System.	FOXP2 FOXP1	1.57e-05	3	80	2	28507505
Pubmed	Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.	UNC13B UNC13A	1.57e-05	3	80	2	17639022
Pubmed	Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain.	FOXP2 FOXP1	1.57e-05	3	80	2	12687690
Pubmed	A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain.	AGO2 AGO1	1.57e-05	3	80	2	17891150
Pubmed	Foxp1 expression is essential for sex-specific murine neonatal ultrasonic vocalization.	FOXP2 FOXP1	1.57e-05	3	80	2	28204507
Pubmed	Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.	BRCA1 SSX2IP OBSCN GTF2IRD1 DDX39A	2.50e-05	149	80	5	25184681
Pubmed	Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.	UNC13B UNC13C UNC13A	2.93e-05	26	80	3	17124501
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	ORC5 NCAPD3 AGO2 MDN1 IPO7 CCT3 TOM1 HAT1 DHX33 PFKM PRPF8 DDX39A	2.94e-05	1257	80	12	37317656
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP104 ZFYVE28 NCAPD3 AGO2 TRANK1 USP28 LRCH1 KCNT1	3.02e-05	529	80	8	14621295
Pubmed	Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo.	UNC13B UNC13A	3.13e-05	4	80	2	10488064
Pubmed	Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression.	AGO2 AGO1	3.13e-05	4	80	2	20671708
Pubmed	Transcriptional and DNA binding activity of the Foxp1/2/4 family is modulated by heterotypic and homotypic protein interactions.	FOXP2 FOXP1	3.13e-05	4	80	2	14701752
Pubmed	Retroviral GAG proteins recruit AGO2 on viral RNAs without affecting RNA accumulation and translation.	AGO2 AGO1	3.13e-05	4	80	2	21948796
Pubmed	Molecular dissection of human Argonaute proteins by DNA shuffling.	AGO2 AGO1	3.13e-05	4	80	2	23748378
Interaction	CDC5L interactions	TANC2 ORC5 STK36 MDN1 ZBTB7C IPO7 BRCA1 CCT3 FOXP2 FOXP1 PFKM PRPF8 DDX39A CCDC136	5.25e-06	855	79	14	int:CDC5L
Interaction	C3orf18 interactions	ORC5 NCAPD3 MDN1 TTI1 SEC63 DDX39A	6.00e-06	115	79	6	int:C3orf18
GeneFamily	UNC13 homologs	UNC13B UNC13C UNC13A	1.19e-07	4	57	3	836
GeneFamily	Potassium sodium-activated channel subfamily T	KCNT2 KCNT1	9.77e-06	2	57	2	856
GeneFamily	Argonaute/PIWI family	AGO2 AGO1	2.70e-04	8	57	2	408
GeneFamily	Forkhead boxes	FOXP2 FOXP1 FOXR2	3.35e-04	43	57	3	508
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	TAB2 RBCK1	1.97e-03	21	57	2	89
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TANC2 TRANK1 DNAJC3	5.71e-03	115	57	3	769
Coexpression	GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN	CEP104 ATP6V1G2 AGO2 TRANK1 STON2 LRCH1	2.40e-05	190	79	6	M6589
Coexpression	GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_DN	STK10 MDN1 FOXP1 PFKM RBCK1 SCAF4	3.20e-05	200	79	6	M8278
Coexpression	GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	ORC5 RMND5B STK36 ADAM19 RANBP6 PRPF8	3.20e-05	200	79	6	M7532
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	NCAPD3 MDN1 BRCA1 CCT3 USP28 HAT1 HEATR1 DHX33	3.04e-05	333	78	8	gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	UNC13B ORC5 ATP6V1G2 AGO1 IPO7 BRCA1 STON2 HAT1 TTI1 HEATR1 DMD GTF2IRD1 SCAF4	5.93e-05	989	78	13	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 OBSCN UNC13C GRIP2 ADAMTSL3	5.25e-08	190	80	7	be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 NECAB2 TRANK1 FOXP2 KCNT1	9.46e-07	182	80	6	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 NECAB2 TRANK1 FOXP2 KCNT1	9.46e-07	182	80	6	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 TRANK1 DNAH10 OBSCN UNC13C DMD	1.01e-06	184	80	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 TRANK1 DNAH10 OBSCN UNC13C DMD	1.01e-06	184	80	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 TRANK1 DNAH10 OBSCN UNC13C DMD	1.01e-06	184	80	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 ROR2 UNC13C GRIP2 OR14C36 ADAMTSL3	1.04e-06	185	80	6	6e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.18e-06	189	80	6	979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 OBSCN GRIP2 ADAMTSL3	1.21e-06	190	80	6	3b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 OBSCN GRIP2 ADAMTSL3	1.21e-06	190	80	6	dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.29e-06	192	80	6	342842378c20267c5044bdd622515e8b9f895623
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.29e-06	192	80	6	bd3fa6c8fcb618db64d11f25cabaf08608957c35
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.33e-06	193	80	6	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.33e-06	193	80	6	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.41e-06	195	80	6	98ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	AGO2 FOXP1 TAB2 DHX33 DMD NOTCH3	1.59e-06	199	80	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2--L1-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.64e-06	200	80	6	f268cb1bb047e88913a828614b0a77871f5f8814
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.64e-06	200	80	6	5ff9ac97ef970b3b74ebb07f62a0a1f4176a10b4
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.64e-06	200	80	6	e90155498397524b812c46f2412320230b445bb6
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-LCP2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SLC32A1 NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	1.64e-06	200	80	6	7345cc7dc24b9174541a3e68ecac8c4c092be400
ToppCell	droplet-Heart-HEART-1m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ORC5 STON2 HEATR1 ABCD1 PFKFB4	3.36e-06	127	80	5	983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_ALM_Trhr_Nefl\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UNC13B FOXP2 FOXP1 UNC13C CHN2	7.33e-06	149	80	5	558a441804dbcd5b5f39a3b1933b48976711ff15
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	UNC13C GRIP2 PFKM GTF2IRD1 KCNT1	8.88e-06	155	80	5	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OBSCN UNC13C GRIP2 DMD KCNB2	1.27e-05	167	80	5	91b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	STK10 ADAM19 DNAH10 WDR35 LRCH1	1.55e-05	174	80	5	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNT2 FOXP2 UNC13C KCNB2 CHN2	1.60e-05	175	80	5	06af6629766e2054e6995e8cdb3907658fec49d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C GRIP2 DMD UNC13A NOTCH3	1.60e-05	175	80	5	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C GRIP2 DMD UNC13A NOTCH3	1.60e-05	175	80	5	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	1.69e-05	177	80	5	b75f519d72611b293d9684f7dcfb1b70fbf54a90
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 ZBTB7C SSX2IP UNC13A NOTCH3	1.69e-05	177	80	5	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 ZBTB7C SSX2IP UNC13A NOTCH3	1.69e-05	177	80	5	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ATP6V1G2 KCNT2 FOXP2 UNC13C CHN2	1.73e-05	178	80	5	a48739a588f361b4bc69405d7e256c11f61cf43c
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GOT1L1 KCNT2 ROR2 UNC13C KCNB2	1.83e-05	180	80	5	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HGD FOXP2 UNC13C CHN2 CCDC136	1.83e-05	180	80	5	a407376209d80177bf7fc4200219030c83cb5f14
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	2.03e-05	184	80	5	e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_RCN1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRIM64B NECAB2 CYP19A1 KPRP GRIP2	2.09e-05	185	80	5	538db481c82b02e5d3b8e03b166f754cc936901e
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	KCNT2 ROR2 DMD KCNB2 ADAMTSL3	2.20e-05	187	80	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ADAM19 OBSCN GRIP2 DMD GTF2IRD1	2.25e-05	188	80	5	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRANK1 ZBTB7C FOXP2 DMD ADAMTSL3	2.25e-05	188	80	5	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NECAB2 ROR2 UNC13C GRIP2 ADAMTSL3	2.25e-05	188	80	5	4544552ebd67e9eb3e40d8511bb2b03a6e1178f8
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 NECAB2 TRANK1 FOXP2	2.31e-05	189	80	5	3e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C KCNT2 GRIP2 DMD NOTCH3	2.31e-05	189	80	5	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C KCNT2 GRIP2 DMD NOTCH3	2.31e-05	189	80	5	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 NECAB2 TRANK1 FOXP2	2.31e-05	189	80	5	851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2	2.37e-05	190	80	5	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	2.37e-05	190	80	5	56cc761e50fddfb5366391518b4d8e16589b6b42
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 NECAB2 TRANK1 FOXP2	2.37e-05	190	80	5	1c5cf933ce71fed5638b9ef31eb81f6c2b6dadbc
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRANK1 ZBTB7C ROR2 DMD ADAMTSL3	2.37e-05	190	80	5	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 KCNT2 ROR2 DMD ADAMTSL3	2.37e-05	190	80	5	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	2.37e-05	190	80	5	25d4b591f75c26e404a34c42f1742d580af6598d
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 KCNT2 ROR2 DMD ADAMTSL3	2.37e-05	190	80	5	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	USP28 OBSCN GRIP2 DMD GTF2IRD1	2.43e-05	191	80	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZBTB7C KCNT2 DMD ADAMTSL3 NOTCH3	2.43e-05	191	80	5	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZBTB7C KCNT2 DMD ADAMTSL3 NOTCH3	2.43e-05	191	80	5	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB7C GRIP2 DMD UNC13A NOTCH3	2.43e-05	191	80	5	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	2.49e-05	192	80	5	f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2	2.49e-05	192	80	5	63d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	2.49e-05	192	80	5	690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 GRIP2 KCNB2 ADAMTSL3 CCDC136	2.55e-05	193	80	5	010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 TRANK1 FOXP2 DMD NOTCH3	2.55e-05	193	80	5	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2	2.62e-05	194	80	5	52aebb0b563e2c2058e7f0554ae870e47692b163
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	2.62e-05	194	80	5	6ac759828c41ffa974ee82842162caa959351dd1
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ADAM19 USP28 ROR2 OBSCN DMD	2.62e-05	194	80	5	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 GRIP2 ADAMTSL3	2.62e-05	194	80	5	5d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SLC32A1 NECAB2 ROR2 UNC13C GRIP2	2.62e-05	194	80	5	bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	TANC2 ADAM19 FOXP2 STON2 ADAMTSL3	2.68e-05	195	80	5	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	Control-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	TANC2 ADAM19 FOXP2 STON2 ADAMTSL3	2.75e-05	196	80	5	e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 IPO7 CCT3 DMD NOTCH3	2.82e-05	197	80	5	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	ZBTB7C KCNT2 DMD ADAMTSL3 NOTCH3	3.03e-05	200	80	5	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Interneuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	SLC32A1 ATP6V1G2 FOXP2 FOXP1 UNC13C	3.03e-05	200	80	5	08bee924a2654e05df3b39e8a51f93c8b3472175
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	UNC13C GRIP2 PFKM KCNT1	1.32e-04	144	80	4	f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Liver / Manually curated celltypes from each tissue	BRCA1 ANKAR GAL3ST2 PFKM	1.71e-04	154	80	4	c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KCNT2 DMD ADAMTSL3 NOTCH3	1.79e-04	156	80	4	6365b69ede98bc866e996bc52736b00401aacf6f
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 ROR2 DHX33 DMD	1.93e-04	159	80	4	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SLC32A1 RANBP6 GRIP2 CCDC136	2.02e-04	161	80	4	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNT2 ROR2 DMD KCNB2	2.17e-04	164	80	4	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC32A1 NECAB2 TRANK1 FOXP2	2.22e-04	165	80	4	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC32A1 NECAB2 TRANK1 FOXP2	2.22e-04	165	80	4	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNT2 ROR2 DMD KCNB2	2.27e-04	166	80	4	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 ORC5 USP28 CIAO2A	2.38e-04	168	80	4	93b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HGD KCNT2 SSX2IP STON2	2.38e-04	168	80	4	2d056cfbb470a088a0682576753535fb4528d48f
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 ORC5 USP28 CIAO2A	2.38e-04	168	80	4	e393553208617a023f1646169c892a87c95db3f5
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HGD KCNT2 SSX2IP STON2	2.38e-04	168	80	4	2f69e248c6fab1421c0081e01e1920e6ffcde344
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNT2 FOXP2 UNC13C CHN2	2.54e-04	171	80	4	9e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZBTB7C GRIP2 DMD NOTCH3	2.54e-04	171	80	4	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GOT1L1 KCNT2 ROR2 UNC13C	2.66e-04	173	80	4	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB7C FOXP2 UNC13C KCNB2	2.66e-04	173	80	4	8335b77f730ed43fc348a005566e73a103c6774b
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	NECAB2 OBSCN ADAMTSL3 NOTCH3	2.66e-04	173	80	4	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNT2 FOXP2 UNC13C CHN2	2.66e-04	173	80	4	5aa4d45a01d2d09eff8b4deb32bd91ab2471210a
ToppCell	COVID-19-Heart-VSMC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ZBTB7C DMD KCNT1 NOTCH3	2.78e-04	175	80	4	1125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	NECAB2 FOXP2 CCDC136 UNC13A	2.84e-04	176	80	4	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNT2 BRCA1 FOXP2 DMD	2.84e-04	176	80	4	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	facs-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 KCNT2 ADAMTSL3	2.90e-04	177	80	4	17065d37fd41f04f67282bee00365daa185e8355
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNT2 ROR2 DMD KCNB2	2.90e-04	177	80	4	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	facs-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 KCNT2 ADAMTSL3	2.90e-04	177	80	4	6e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCell	facs-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 SLC32A1 KCNT2 ADAMTSL3	2.90e-04	177	80	4	9ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNT2 FOXP2 UNC13C CHN2	2.90e-04	177	80	4	7e799333307448c6a94d1f33dbc59c543336f45e
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC32A1 NECAB2 FOXP2 KCNT1	3.03e-04	179	80	4	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|COVID-19_Convalescent / Disease condition and Cell class	ADAM19 MDN1 PFKFB4 LRCH1	3.03e-04	179	80	4	366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZBTB7C KCNT2 STON2 ADAMTSL3	3.09e-04	180	80	4	c4068fe47408cfd899131a85fa4b7e5908926f94
Disease	specific developmental disorder (implicated_via_orthology)	FOXP2 FOXP1	4.02e-05	4	77	2	DOID:0060038 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	UNC13B KCNT2 UNC13C KCNT1 UNC13A	6.93e-05	163	77	5	DOID:1826 (implicated_via_orthology)
Disease	progression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian carcinoma	AGO2 FOXP2 DMD	1.46e-04	39	77	3	EFO_0001075, EFO_0004920, GO_0097328, MONDO_0009354
Disease	alcohol use disorder (implicated_via_orthology)	UNC13B SLC32A1 UNC13C UNC13A NOTCH3	1.61e-04	195	77	5	DOID:1574 (implicated_via_orthology)
Disease	Cerebrovascular accident	PRPF8 LRCH1 NOTCH3	5.78e-04	62	77	3	C0038454
Disease	triglyceride measurement, body mass index	STK36 DNAH10	1.12e-03	19	77	2	EFO_0004340, EFO_0004530
Disease	mental or behavioural disorder	ADAM19 KCNT2 ABCD1 DMD	1.26e-03	179	77	4	EFO_0000677
Disease	esophagus adenocarcinoma (is_implicated_in)	CYP19A1 FOXP1	1.37e-03	21	77	2	DOID:4914 (is_implicated_in)
Disease	body weight	UNC13B ZBTB7C FOXP2 C3orf38 CYP19A1 ROR2 DMD KCNB2 ADAMTSL3 CHN2	1.59e-03	1261	77	10	EFO_0004338
Disease	Headache, type 2 diabetes mellitus	FOXP1 ABCD1	1.64e-03	23	77	2	HP_0002315, MONDO_0005148
Disease	neuropsychological test	NCAPD3 UNC13C GRIP2 KCNB2	1.78e-03	197	77	4	EFO_0003926
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	FOXP1 KCNB2	1.79e-03	24	77	2	EFO_0003948, EFO_0009923, MONDO_0004247
Disease	congenital heart disease (is_implicated_in)	FOXP1 TAB2	1.79e-03	24	77	2	DOID:1682 (is_implicated_in)
Disease	childhood trauma measurement	FOXP2 FOXP1	1.79e-03	24	77	2	EFO_0007979
Disease	optic disc size measurement	TANC2 FOXP1 ADAMTSL3 LRCH1	2.06e-03	205	77	4	EFO_0004832
Disease	Colorectal Carcinoma	UNC13B ADAM19 OBSCN HAT1 DMD KCNB2 ADAMTSL3	2.38e-03	702	77	7	C0009402
Disease	migraine disorder	STK10 C3orf38 FOXP1 DMD LRCH1	2.44e-03	357	77	5	MONDO_0005277
Disease	HIV Coinfection	IPO7 CCT3 PRPF8	2.51e-03	103	77	3	C4505456
Disease	HIV Infections	IPO7 CCT3 PRPF8	2.51e-03	103	77	3	C0019693

Protein segments in the cluster

Peptide	Gene	Start	Entry
LAQLLGMVCDVRPQV	ATP6V1G2	96	O95670
VPCILMNNTQQLRVQ	UNC13A	1251	Q9UPW8
PIDTTIIMNGRQIQC	ADAM19	591	Q9H013
IVAVLNCMNELLVLQ	SSX2IP	96	Q9Y2D8
VQRCMALAQLLVEQN	DDX39A	296	O00148
LCMDPDILLNVVEQI	GOT1L1	161	Q8NHS2
QPVIEFMCEVLDIRN	AGO1	226	Q9UL18
NDQPMDILQIINCLT	DMD	3141	P11532
RQLVMLPCSPQIEAQ	DNHD1	1706	Q96M86
IRVCSEVLQMEPDNV	DNAJC3	326	Q13217
AAMENPNLREIVEQC	CIAO2A	141	Q9H5X1
CPRRVNREIVEHMVQ	AGO2	66	Q9UKV8
IINQIMDECIPQDRA	ZFYVE28	66	Q9HCC9
IPKMQRRLQELCQIL	ABCD1	706	P33897
IENVLVNVMNCIRVL	ANKAR	836	Q7Z5J8
EQMEIAIRAILCAIQ	MDN1	4506	Q9NU22
QGEAMRCPQCQIVVQ	RBCK1	441	Q9BYM8
VILCPTEMDVQVRRV	KCNT1	386	Q5JUK3
TINMEECRLRVQVQP	IFI35	101	P80217
LCALIDMEQIPQVLN	IPO7	841	O95373
PVIVNSRICIQMTLA	OR14C36	131	Q8NHC7
NQAVRLPLMECVQVT	PFKM	341	P08237
VIMELERQENVLVIC	PFKFB4	376	Q16877
CRVQMQVVQQLEIQL	FOXP2	381	O15409
CRVQMQVVQQLELQL	FOXP1	341	Q9H334
VVMLEIDNRLCLQSP	NOTCH3	1581	Q9UM47
NLPNDRQMLCITVLL	HEATR6	806	Q6AI08
CIRVIPEAIVNLQML	LRCH1	131	Q9Y2L9
CPTEMDVQVRRVLQI	KCNT2	336	Q6UVM3
ELRIQSPMLQAQEQC	OBSCN	6196	Q5VST9
VQNVINAMQKILECP	BRCA1	11	P38398
HNTQRPMVVDICIRE	CHN2	286	P52757
QTLGVCQRLVMPELQ	GAL3ST2	361	Q9H3Q3
QFPQEIVLQMVERCR	CEP104	41	O60308
CLRPEELTNQMNQIE	HAT1	376	O14929
VAVQAVQAMNRICVL	GUK1	86	Q16774
VQAMNRICVLDVDLQ	GUK1	91	Q16774
MEEVVCPQEQLAVAQ	KCNB2	576	Q92953
LTRENVNQCILEMLI	CYP19A1	291	P11511
IMALCDTVTNRLVQP	C3orf38	26	Q5JPI3
VPEIQRCNLASVMLQ	DHX33	431	Q9H6R0
QRERIQECMSQPELL	FOXR2	291	Q6PJQ5
AQSQVVVQAPCEMQI	KPRP	31	Q5T749
ELIVQCIRLSEMPQT	HEATR1	1286	Q9H583
RMVIINQLQPFAEIC	GTF2IRD1	871	Q9UHL9
NIRLDNCPMEDAVQI	GRIP2	611	Q9C0E4
VVIVPDLQQICEIML	DNAH10	1956	Q8IVF4
QQEMEVEQPCIQEVK	SCAF4	411	O95104
MEAPQRVIPVILQNC	C18orf63	91	Q68DL7
KMLVQPNEICVIQRG	HGD	171	Q93099
DRNEPCHIIQILEIM	TATDN1	256	Q6P1N9
PEVPEVVVSRCMLQN	TAB2	21	Q9NYJ8
MPHLENVVLCRESQV	ORC5	1	O43913
LRVEEECRQMQQPQQ	TANC2	1366	Q9HCD6
LQDAMQVCRNVLLDP	CCT3	391	P49368
CQEMLQEEPRLDVLI	RDH14	126	Q9HBH5
VVEMIRNRQVLPCPD	ROR2	701	Q01974
LINPSCMVRRQAEEI	RANBP6	26	O60518
EELLQCEVPQRLLEM	STK36	1226	Q9NRP7
NRDPLTQVPCENVMI	STON2	716	Q8WXE9
QLCLEEMQLLQVQSP	CCDC136	721	Q96JN2
QSLTELLMAQPRCVQ	NCAPD3	601	P42695
NPQVKEIRCIVMVPQ	PRPF8	2136	Q6P2Q9
ENVPCILMNNIQQLR	UNC13C	1791	Q8NB66
PVLMNIKAVIEQRQC	RMND5B	296	Q96G75
CRAMQQRVLELIPQI	TOM1	261	O60784
EPQIQVVCRQMLEAL	STK10	131	O94804
ALLQEMVNVICQLIV	SEC63	331	Q9UGP8
CILMNNVQQLRVQLE	UNC13B	1171	O14795
CQMLLNQLREITGIQ	USP28	21	Q96RU2
VTQMGQEVILRCVPI	TRBV2	31	A0A1B0GX68
MNCPETIAQIQRDLA	POGLUT2	151	Q6UW63
IQCIVNVCLEIMEPG	ZBTB7C	116	A1YPR0
VNVAQIIELVMTCIL	SLC32A1	206	Q9H598
LCLVMLVNAEEILQP	TRANK1	2521	O15050
CQIMRHENDQNPVLI	WDR35	236	Q9P2L0
LCEININDNMPRILS	WDR91	486	A4D1P6
CHMPDVVLLQDVRNV	TRIM64B	236	A6NI03
LPLQIQIAMDVMERC	TTI1	856	O43156
RIQRPQCVMANGQEV	ADAMTSL3	1446	P82987
QLVRQEMAVCPEQLS	NECAB2	286	Q7Z6G3