Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	MYH8 DYNC2H1 ABCA13 NVL DNAH7 RAD50 CCT6A IGHMBP2 ATP2C2 CCT6B ABCC2 DYNC1H1	1.36e-06	441	96	12	GO:0016887
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DYNC2H1 DNAH7 CCDC88A DYNC1H1	9.40e-06	28	96	4	GO:0051959
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	TPR TRPC4AP RIPK1 ZNF366 NSD1 PFDN5 PRAMEF17 BCOR PPP1R13L RUFY1 TRIP11 ARPC4 RAD50 STX3 KHDRBS1 SUN5 AP1M1	3.46e-05	1160	96	17	GO:0030674
GeneOntologyMolecularFunction	ATP-dependent activity	MYH8 DYNC2H1 ABCA13 NVL DNAH7 RAD50 CCT6A IGHMBP2 ATP2C2 CCT6B ABCC2 DYNC1H1	3.80e-05	614	96	12	GO:0140657
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKD2 PRKD3 PRKD1	5.76e-05	16	96	3	GO:0004697
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DYNC2H1 DNAH7 DYNC1H1	8.34e-05	18	96	3	GO:0008569
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	MYH8 DYNC2H1 ABCA13 NVL GCH1 DNAH7 RAD50 CCT6A IGHMBP2 ATP2C2 CCT6B ABCC2 DYNC1H1	8.47e-05	775	96	13	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	MYH8 DYNC2H1 ABCA13 NVL GCH1 DNAH7 RAD50 CCT6A IGHMBP2 ATP2C2 CCT6B ABCC2 DYNC1H1	1.86e-04	839	96	13	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	MYH8 DYNC2H1 ABCA13 NVL GCH1 DNAH7 RAD50 CCT6A IGHMBP2 ATP2C2 CCT6B ABCC2 DYNC1H1	1.88e-04	840	96	13	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MYH8 DYNC2H1 ABCA13 NVL GCH1 DNAH7 RAD50 CCT6A IGHMBP2 ATP2C2 CCT6B ABCC2 DYNC1H1	1.88e-04	840	96	13	GO:0016818
GeneOntologyMolecularFunction	molecular adaptor activity	TPR TRPC4AP RIPK1 ZNF366 NSD1 PFDN5 PRAMEF17 BCOR PPP1R13L RUFY1 TRIP11 ARPC4 RAD50 STX3 KHDRBS1 SUN5 AP1M1	2.33e-04	1356	96	17	GO:0060090
GeneOntologyMolecularFunction	dynein intermediate chain binding	DYNC2H1 DNAH7 DYNC1H1	7.43e-04	37	96	3	GO:0045505
GeneOntologyBiologicalProcess	regulation of nucleobase-containing compound transport	TPR RIPK1 IWS1 KHDRBS1 SUPT6H	2.74e-08	20	95	5	GO:0032239
GeneOntologyBiologicalProcess	regulation of RNA export from nucleus	TPR IWS1 KHDRBS1 SUPT6H	9.60e-07	17	95	4	GO:0046831
GeneOntologyBiologicalProcess	regulation of mRNA export from nucleus	TPR IWS1 SUPT6H	1.52e-05	11	95	3	GO:0010793
GeneOntologyBiologicalProcess	regulation of ribonucleoprotein complex localization	TPR IWS1 SUPT6H	2.62e-05	13	95	3	GO:2000197
GeneOntologyBiologicalProcess	ribonucleoprotein complex localization	TPR IWS1 SUPT6H	3.32e-05	14	95	3	GO:0071166
GeneOntologyBiologicalProcess	positive regulation of DNA biosynthetic process	PRKD2 NVL GCH1 CCT6A POLG2	3.41e-05	80	95	5	GO:2000573
GeneOntologyBiologicalProcess	regulation of cellular localization	TPR EPS15 KRT5 PDE4C GBF1 NCKAP1 NVL IWS1 CCT6A CCDC88A STX3 KHDRBS1 SUPT6H TBC1D1 SUN5 PRKD1 DYNC1H1	3.48e-05	1212	95	17	GO:0060341
GeneOntologyBiologicalProcess	intracellular transport	TPR EPS15 GBF1 CLTCL1 DYNC2H1 BACH2 RUFY1 TRIP11 IWS1 CCDC88A STX3 ZFYVE9 KHDRBS1 UPF2 SUPT6H KCNQ3 AP1M1 PRKD1 DYNC1H1	4.42e-05	1496	95	19	GO:0046907
GeneOntologyBiologicalProcess	RNA export from nucleus	TPR IWS1 KHDRBS1 UPF2 SUPT6H	8.18e-05	96	95	5	GO:0006405
GeneOntologyBiologicalProcess	nuclear export	TPR IWS1 KHDRBS1 UPF2 SUPT6H PRKD1	2.15e-04	185	95	6	GO:0051168
GeneOntologyCellularComponent	cilium	SPATA7 EPS15 PDE4C DYNC2H1 EVC PRAMEF17 DNAH7 QRICH2 TULP3 ENO4 CFAP54 CCDC88A STX3 NIN	5.94e-05	898	96	14	GO:0005929
GeneOntologyCellularComponent	dynein complex	TPR DYNC2H1 DNAH7 DYNC1H1	1.11e-04	54	96	4	GO:0030286
GeneOntologyCellularComponent	cytoplasmic dynein complex	TPR DYNC2H1 DYNC1H1	1.77e-04	24	96	3	GO:0005868
GeneOntologyCellularComponent	cytoplasmic region	SPATA7 DYNC2H1 PCLO GRIA2 DNAH7 TULP3 CFAP54 DYNC1H1	2.54e-04	360	96	8	GO:0099568
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	SPATA7 DYNC2H1 GRIA2 DNAH7 TULP3 CFAP54 DYNC1H1	6.50e-04	317	96	7	GO:0032838
GeneOntologyCellularComponent	clathrin vesicle coat	EPS15 CLTCL1 AP1M1	7.05e-04	38	96	3	GO:0030125
GeneOntologyCellularComponent	inclusion body	TPR EPS15 RAD50 WDFY3	7.89e-04	90	96	4	GO:0016234
GeneOntologyCellularComponent	chaperonin-containing T-complex	CCT6A CCT6B	1.12e-03	11	96	2	GO:0005832
Domain	Protein_Kinase_C_mu-related	PRKD2 PRKD3 PRKD1	1.36e-07	3	97	3	IPR015727
Domain	AAA+_ATPase	DYNC2H1 ABCA13 NVL DNAH7 IGHMBP2 ABCC2 DYNC1H1	1.01e-05	144	97	7	IPR003593
Domain	AAA	DYNC2H1 ABCA13 NVL DNAH7 IGHMBP2 ABCC2 DYNC1H1	1.01e-05	144	97	7	SM00382
Domain	DUF3350	TBC1D4 TBC1D1	2.67e-05	2	97	2	PF11830
Domain	Chap_CCT_zeta	CCT6A CCT6B	2.67e-05	2	97	2	IPR012722
Domain	DUF3350	TBC1D4 TBC1D1	2.67e-05	2	97	2	IPR021785
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH7 DYNC1H1	4.74e-05	14	97	3	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH7 DYNC1H1	4.74e-05	14	97	3	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH7 DYNC1H1	4.74e-05	14	97	3	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH7 DYNC1H1	4.74e-05	14	97	3	PF08393
Domain	MT	DYNC2H1 DNAH7 DYNC1H1	4.74e-05	14	97	3	PF12777
Domain	AAA_8	DYNC2H1 DNAH7 DYNC1H1	4.74e-05	14	97	3	PF12780
Domain	DHC_fam	DYNC2H1 DNAH7 DYNC1H1	5.91e-05	15	97	3	IPR026983
Domain	Dynein_heavy_dom	DYNC2H1 DNAH7 DYNC1H1	5.91e-05	15	97	3	IPR004273
Domain	Dynein_heavy	DYNC2H1 DNAH7 DYNC1H1	5.91e-05	15	97	3	PF03028
Domain	-	PCGF2 TRIM35 PCLO NSD1 TRIM43 RUFY1 TRIM43B ZFYVE9 DZIP3 WDFY3	1.13e-04	449	97	10	3.30.40.10
Domain	Znf_RING/FYVE/PHD	PCGF2 TRIM35 PCLO NSD1 TRIM43 RUFY1 TRIM43B ZFYVE9 DZIP3 WDFY3	1.36e-04	459	97	10	IPR013083
Domain	DAG/PE-bd	PRKD2 PRKD3 PRKD1	1.69e-04	21	97	3	IPR020454
Domain	FYVE	RUFY1 ZFYVE9 WDFY3	4.50e-04	29	97	3	PF01363
Domain	FYVE	RUFY1 ZFYVE9 WDFY3	4.50e-04	29	97	3	SM00064
Domain	Prefoldin	TPR EPS15 PFDN5 RUFY1	5.37e-04	72	97	4	IPR009053
Domain	Znf_FYVE-rel	RUFY1 ZFYVE9 WDFY3	7.23e-04	34	97	3	IPR017455
Domain	DHC_N1	DYNC2H1 DYNC1H1	7.32e-04	8	97	2	PF08385
Domain	Dynein_heavy_dom-1	DYNC2H1 DYNC1H1	7.32e-04	8	97	2	IPR013594
Domain	Chaprnin_Cpn60	CCT6A CCT6B	9.39e-04	9	97	2	IPR001844
Domain	Chaperonin_TCP-1_CS	CCT6A CCT6B	9.39e-04	9	97	2	IPR002194
Domain	Znf_FYVE	RUFY1 ZFYVE9 WDFY3	1.00e-03	38	97	3	IPR000306
Domain	Znf_FYVE_PHD	PCLO NSD1 RUFY1 ZFYVE9 WDFY3	1.02e-03	147	97	5	IPR011011
Domain	ZF_FYVE	RUFY1 ZFYVE9 WDFY3	1.17e-03	40	97	3	PS50178
Domain	TCP1_1	CCT6A CCT6B	1.17e-03	10	97	2	PS00750
Domain	TCP1_2	CCT6A CCT6B	1.17e-03	10	97	2	PS00751
Domain	TCP1_3	CCT6A CCT6B	1.17e-03	10	97	2	PS00995
Domain	Chaperone_TCP-1	CCT6A CCT6B	1.17e-03	10	97	2	IPR017998
Domain	-	CCT6A CCT6B	1.42e-03	11	97	2	3.30.260.10
Domain	TCP-1-like_intermed	CCT6A CCT6B	1.42e-03	11	97	2	IPR027410
Domain	t-SNARE	MSR1 STX3 RASSF6	1.44e-03	43	97	3	IPR010989
Domain	Znf_RING	PCGF2 TRIM35 NSD1 TRIM43 RUFY1 TRIM43B DZIP3	1.55e-03	326	97	7	IPR001841
Domain	ARM-type_fold	RALGAPA1 TRPC4AP GBF1 CLTCL1 UPF2 PDS5A WDFY3	1.94e-03	339	97	7	IPR016024
Domain	NPIP	NPIPB2 NPIPA2	2.33e-03	14	97	2	IPR009443
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DYNC1H1	2.33e-03	14	97	2	IPR011704
Domain	-	CCT6A CCT6B	2.33e-03	14	97	2	1.10.560.10
Domain	GROEL-like_equatorial	CCT6A CCT6B	2.33e-03	14	97	2	IPR027413
Domain	AAA_5	DYNC2H1 DYNC1H1	2.33e-03	14	97	2	PF07728
Domain	Cpn60/TCP-1	CCT6A CCT6B	2.68e-03	15	97	2	IPR002423
Domain	Cpn60_TCP1	CCT6A CCT6B	2.68e-03	15	97	2	PF00118
Domain	-	CCT6A CCT6B	2.68e-03	15	97	2	3.50.7.10
Domain	GroEL-like_apical_dom	CCT6A CCT6B	2.68e-03	15	97	2	IPR027409
Domain	C1_1	PRKD2 PRKD3 PRKD1	3.24e-03	57	97	3	PF00130
Domain	PDEase	PDE4A PDE4C	4.31e-03	19	97	2	IPR023088
Domain	ZF_DAG_PE_1	PRKD2 PRKD3 PRKD1	4.50e-03	64	97	3	PS00479
Domain	ZF_DAG_PE_2	PRKD2 PRKD3 PRKD1	4.50e-03	64	97	3	PS50081
Domain	C1	PRKD2 PRKD3 PRKD1	4.70e-03	65	97	3	SM00109
Domain	PE/DAG-bd	PRKD2 PRKD3 PRKD1	4.90e-03	66	97	3	IPR002219
Domain	RING	PCGF2 TRIM35 NSD1 TRIM43 TRIM43B DZIP3	5.15e-03	305	97	6	SM00184
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPR EPS15 PDE4A NCKAP1 MCC NSD1 GRIA2 BCOR JAKMIP2 TRIP11 ARPC4 RAD50 CCDC88A DZIP3 PRKD1 WDFY3 DYNC1H1 LRRFIP2	2.01e-10	963	98	18	28671696
Pubmed	Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.	PRKD2 PRKD3 PRKD1	2.17e-08	3	98	3	26253275
Pubmed	Expression of the protein kinase D (PKD) family during mouse embryogenesis.	PRKD2 PRKD3 PRKD1	2.17e-08	3	98	3	16377259
Pubmed	A Novel Conserved Domain Mediates Dimerization of Protein Kinase D (PKD) Isoforms: DIMERIZATION IS ESSENTIAL FOR PKD-DEPENDENT REGULATION OF SECRETION AND INNATE IMMUNITY.	PRKD2 PRKD3 PRKD1	2.17e-08	3	98	3	27662904
Pubmed	Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.	PRKD2 PRKD3 PRKD1	2.17e-08	3	98	3	32747433
Pubmed	Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland.	PRKD2 PRKD3 PRKD1	2.17e-08	3	98	3	26426580
Pubmed	Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.	PRKD2 PRKD3 PRKD1	2.17e-08	3	98	3	38419169
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SPATA7 TRPC4AP NCKAP1 DYNC2H1 MCC PPP1R13L TRIP11 ARPC4 MTFR1L TULP3 RAD50 CCDC88A TBC1D4 TBC1D1 DZIP3 PRKD1 METTL25 DYNC1H1	2.79e-08	1321	98	18	27173435
Pubmed	Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network.	PRKD2 PRKD3 PRKD1	8.66e-08	4	98	3	14743217
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	KRT5 NCKAP1 ACOT9 BACH2 PFDN5 RUFY1 DNAH7 RAD50 CCT6A CCDC88A TBC1D1 CCT6B DYNC1H1 NIN	1.24e-07	853	98	14	28718761
Pubmed	Protein kinase D regulates RhoA activity via rhotekin phosphorylation.	PRKD2 PRKD3 PRKD1	2.16e-07	5	98	3	22228765
Pubmed	Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation.	EPS15 CLTCL1 PCLO ZFYVE9 AP1M1	4.54e-07	54	98	5	25496667
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	TPR CLTCL1 NCKAP1 PSMB2 MCC PFDN5 ARPC4 RAD50 CCT6A UPF2 SUPT6H AP1M1 DYNC1H1	7.73e-07	847	98	13	35235311
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KRT5 DYNC2H1 BACH2 BCOR RUFY1 TRIP11 RAD50 CCDC88A TBC1D4 SUPT6H NIN	8.73e-07	588	98	11	38580884
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TPR PRKD2 GBF1 NCKAP1 DYNC2H1 PCLO PSMB2 UTP14A RAD50 CCT6A KHDRBS1 SUPT6H AP1M1 PDS5A DYNC1H1 LRRFIP2	2.31e-06	1425	98	16	30948266
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	GBF1 UTP14A BCOR CCT6A TBC1D4 KHDRBS1 DYNC1H1	4.44e-06	232	98	7	25515538
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DYNC2H1 DNAH7 DYNC1H1	7.72e-06	14	98	3	9373155
Pubmed	[Screening for tetrahydrobiopterin metabolic disorders and related gene analysis among the patients with motor disturbance and mental retardation].	GCH1 PTS	7.86e-06	2	98	2	17407085
Pubmed	Rab GAPs AS160 and Tbc1d1 play nonredundant roles in the regulation of glucose and energy homeostasis in mice.	TBC1D4 TBC1D1	7.86e-06	2	98	2	26625902
Pubmed	Protein kinase d isoforms differentially modulate cofilin-driven directed cell migration.	PRKD2 PRKD3	7.86e-06	2	98	2	24840177
Pubmed	Protein kinase Ds promote tumor angiogenesis through mast cell recruitment and expression of angiogenic factors in prostate cancer microenvironment.	PRKD2 PRKD3	7.86e-06	2	98	2	30841931
Pubmed	Does TBC1D4 (AS160) or TBC1D1 Deficiency Affect the Expression of Fatty Acid Handling Proteins in the Adipocytes Differentiated from Human Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Obtained from Subcutaneous and Visceral Fat Depots?	TBC1D4 TBC1D1	7.86e-06	2	98	2	34208471
Pubmed	Sustained AS160 and TBC1D1 phosphorylations in human skeletal muscle 30 min after a single bout of exercise.	TBC1D4 TBC1D1	7.86e-06	2	98	2	24876356
Pubmed	Both the establishment and maintenance of neuronal polarity require the activity of protein kinase D in the Golgi apparatus.	PRKD2 PRKD1	7.86e-06	2	98	2	18753385
Pubmed	Sex and fiber type independently influence AMPK, TBC1D1, and TBC1D4 at rest and during recovery from high-intensity exercise in humans.	TBC1D4 TBC1D1	7.86e-06	2	98	2	31895596
Pubmed	Mutations in the GTP cyclohydrolase I and 6-pyruvoyl-tetrahydropterin synthase genes.	GCH1 PTS	7.86e-06	2	98	2	9222755
Pubmed	Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity.	PRKD2 PRKD1	7.86e-06	2	98	2	25639845
Pubmed	Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle.	TBC1D4 TBC1D1	7.86e-06	2	98	2	22318952
Pubmed	Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4.	PDE4A PDE4C	7.86e-06	2	98	2	23043089
Pubmed	The role of PKD in cell polarity, biosynthetic pathways, and organelle/F-actin distribution.	PRKD2 PRKD1	7.86e-06	2	98	2	24492625
Pubmed	Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells.	PRKD2 PRKD1	7.86e-06	2	98	2	20819079
Pubmed	Differential expression of PKD1 and PKD2 in gastric cancer and analysis of PKD1 and PKD2 function in the model system.	PRKD2 PRKD1	7.86e-06	2	98	2	22217708
Pubmed	Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.	DYNC2H1 DYNC1H1	7.86e-06	2	98	2	25502651
Pubmed	Genetic analysis of the cytoplasmic dynein subunit families.	DYNC2H1 DYNC1H1	7.86e-06	2	98	2	16440056
Pubmed	Illumination of the Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle.	TBC1D4 TBC1D1	7.86e-06	2	98	2	35192682
Pubmed	Opposing growth regulatory roles of protein kinase D isoforms in human keratinocytes.	PRKD2 PRKD3	7.86e-06	2	98	2	25802335
Pubmed	Mutations in Ciliary Trafficking Genes affect Sonic Hedgehog-dependent Neural Tube Patterning Differentially along the Anterior-Posterior Axis.	DYNC2H1 TULP3	7.86e-06	2	98	2	32682825
Pubmed	Genomic analysis of recurrences and high-grade forms of polymorphous adenocarcinoma.	PRKD2 PRKD1	7.86e-06	2	98	2	30843621
Pubmed	Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.	IWS1 SUPT6H	7.86e-06	2	98	2	30208029
Pubmed	Protein kinases D2 and D3 are novel growth regulators in HCC1806 triple-negative breast cancer cells.	PRKD2 PRKD3	7.86e-06	2	98	2	23393329
Pubmed	Focused screening of a panel of cancer-related genetic polymorphisms reveals new susceptibility loci for pediatric acute lymphoblastic leukemia.	PPP1R13L MSR1	7.86e-06	2	98	2	24604828
Pubmed	Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice.	TBC1D4 TBC1D1	7.86e-06	2	98	2	29481597
Pubmed	Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1.	TBC1D4 TBC1D1	7.86e-06	2	98	2	34561225
Pubmed	“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].	TBC1D4 TBC1D1	7.86e-06	2	98	2	25249576
Pubmed	Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases.	PRKD2 PRKD1	7.86e-06	2	98	2	24336522
Pubmed	Protein kinase D3 conditional knockout impairs osteoclast formation and increases trabecular bone volume in male mice.	PRKD2 PRKD3	7.86e-06	2	98	2	37044359
Pubmed	Molecular cloning and characterization of MT-ACT48, a novel mitochondrial acyl-CoA thioesterase.	EPS15 ACOT9	7.86e-06	2	98	2	10383425
Pubmed	The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.	PFDN5 CCT6A CCT6B	9.63e-06	15	98	3	30955883
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	TPR KRT5 NCKAP1 ACOT9 PSMB2 UTP14A ARPC4 IWS1 RAD50 CCT6A TBC1D4 SUPT6H AP1M1 PDS5A DYNC1H1	9.85e-06	1415	98	15	28515276
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT5 MYH8 CLTCL1 PCLO UTP14A GRIA2 TRIM43 ARPC4 TRIM43B CCT6A STX3 KHDRBS1 CEP112 ABCC2 METTL25	1.23e-05	1442	98	15	35575683
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SPATA7 EPS15 KRT5 UTP14A RUFY1 TRIP11 DNAH7 CCT6A CCDC88A PDS5A DYNC1H1	1.24e-05	777	98	11	35844135
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	GBF1 NCKAP1 RAD50 CCT6A TBC1D4 KHDRBS1 SUPT6H AP1M1 PDS5A DYNC1H1	1.32e-05	638	98	10	33239621
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	TPR NCKAP1 PFDN5 ARPC4 CCT6A PAPOLA CCT6B DYNC1H1 LRRFIP2	1.36e-05	506	98	9	30890647
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	EPS15 GBF1 NCKAP1 PSMB2 PFDN5 RUFY1 ARPC4 IWS1 CCT6A TKFC TBC1D4 PAPOLA AP1M1 DYNC1H1 CRTAP	1.37e-05	1455	98	15	22863883
Pubmed	An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.	PFDN5 CCT6A CCT6B	1.43e-05	17	98	3	21572988
Pubmed	Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.	ZNF366 UTP14A IKZF1 PFDN5 RUFY1 JAKMIP2 ARPC4 MTFR1L TULP3 MSR1 STX3 ZFYVE9 PTS DZIP3 LRRFIP2	1.63e-05	1477	98	15	31515488
Pubmed	Recombinant human cytoplasmic dynein heavy chain 1 and 2: observation of dynein-2 motor activity in vitro.	DYNC2H1 DYNC1H1	2.35e-05	3	98	2	21723285
Pubmed	Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes.	PRKD2 PRKD1	2.35e-05	3	98	2	26045048
Pubmed	The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle via Fatty Acid Transporter SLC27A4/FATP4.	TBC1D4 TBC1D1	2.35e-05	3	98	2	32868338
Pubmed	Cytoplasmic dynein promotes HIV-1 uncoating.	DYNC2H1 DYNC1H1	2.35e-05	3	98	2	25375884
Pubmed	A role for PKD1 and PKD3 activation in modulation of calcium oscillations induced by orexin receptor 1 stimulation.	PRKD3 PRKD1	2.35e-05	3	98	2	20621130
Pubmed	Protein kinase D in vascular biology and angiogenesis.	PRKD2 PRKD1	2.35e-05	3	98	2	21488147
Pubmed	Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation.	TBC1D4 TBC1D1	2.35e-05	3	98	2	18258599
Pubmed	Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation.	TBC1D4 TBC1D1	2.35e-05	3	98	2	30257216
Pubmed	Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1.	CCT6A CCT6B	2.35e-05	3	98	2	9013858
Pubmed	Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.	DYNC2H1 DYNC1H1	2.35e-05	3	98	2	8666668
Pubmed	Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.	PRKD2 PRKD1	2.35e-05	3	98	2	20497126
Pubmed	Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking.	TBC1D4 TBC1D1	2.35e-05	3	98	2	27929607
Pubmed	Ikaros regulation of the BCL6/BACH2 axis and its clinical relevance in acute lymphoblastic leukemia.	BACH2 IKZF1	2.35e-05	3	98	2	28030830
Pubmed	The integrase cofactor LEDGF/p75 associates with Iws1 and Spt6 for postintegration silencing of HIV-1 gene expression in latently infected cells.	IWS1 SUPT6H	2.35e-05	3	98	2	25590759
Pubmed	The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity.	PRKD2 PRKD1	2.35e-05	3	98	2	19581308
Pubmed	Molecular and metabolic bases of tetrahydrobiopterin (BH4) deficiencies.	GCH1 PTS	2.35e-05	3	98	2	33903016
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	TPR NCKAP1 PSMB2 UTP14A ARPC4 RAD50 CCT6A TBC1D4 UPF2 CCT6B AP1M1 PDS5A WDFY3 DYNC1H1	2.62e-05	1353	98	14	29467282
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PRKD2 NCKAP1 ARPC4 RAD50 CCT6A KHDRBS1 UPF2 AP1M1 PDS5A DYNC1H1	3.06e-05	704	98	10	29955894
Pubmed	Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage.	TPR KRT5 CCT6A CCT6B AP1M1	3.60e-05	131	98	5	28031328
Pubmed	Charcot-Marie-Tooth Neuropathy Type 2 – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	IGHMBP2 DHTKD1 DYNC1H1	3.69e-05	23	98	3	20301462
Pubmed	Functional proteomics mapping of a human signaling pathway.	PRKD2 EPS15 L1TD1 PPP1R13L ZFYVE9 KHDRBS1 PAPOLA TBC1D1 DYNC1H1	4.57e-05	591	98	9	15231748
Pubmed	Common variations in 4p locus are related to male completed suicide.	EVC TBC1D1	4.70e-05	4	98	2	19115052
Pubmed	Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.	TBC1D4 TBC1D1	4.70e-05	4	98	2	21454505
Pubmed	The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.	IWS1 SUPT6H	4.70e-05	4	98	2	19141475
Pubmed	Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.	PDE4A PDE4C	4.70e-05	4	98	2	9371714
Pubmed	Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.	PRKD2 PRKD1	4.70e-05	4	98	2	28428613
Pubmed	SARA and RNF11 at the crossroads of EGFR signaling and trafficking.	EPS15 ZFYVE9	4.70e-05	4	98	2	24377927
Pubmed	Ibudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphine.	PDE4A PDE4C	4.70e-05	4	98	2	24732776
Pubmed	Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis.	EPS15 MSR1	4.70e-05	4	98	2	35389885
Pubmed	Assessment of PDE4 Inhibitor-Induced Hypothermia as a Correlate of Nausea in Mice.	PDE4A PDE4C	4.70e-05	4	98	2	34943270
Pubmed	Tetrahydrobiopterin biosynthesis, regeneration and functions.	GCH1 PTS	4.70e-05	4	98	2	10727395
Pubmed	Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice.	TBC1D4 TBC1D1	4.70e-05	4	98	2	22253718
Pubmed	WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.	TBC1D4 TBC1D1	4.70e-05	4	98	2	31816312
Pubmed	Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1.	PRKD2 PRKD3	4.70e-05	4	98	2	27670070
Pubmed	PAN-selective inhibition of cAMP-phosphodiesterase 4 (PDE4) induces gastroparesis in mice.	PDE4A PDE4C	4.70e-05	4	98	2	32738081
Pubmed	A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs.	PDE4A PDE4C	4.70e-05	4	98	2	8413254
Pubmed	[Screening of tetrahydrobiopterin deficiency among hyperphenylalaninemic patients].	GCH1 PTS	4.70e-05	4	98	2	11937441
Pubmed	The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway.	TPR KHDRBS1	4.70e-05	4	98	2	21613532
Pubmed	Role of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion.	PDE4A PDE4C	4.70e-05	4	98	2	22946044
Pubmed	Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice.	PDE4A PDE4C	4.70e-05	4	98	2	33609559
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	TPR KRT5 UTP14A IKZF1 RAD50 SUPT6H DYNC1H1	5.18e-05	340	98	7	29478914
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	PRKD2 EPS15 MYH8 RIPK1 NCKAP1 ACOT9 GRIA2 RAD50 PRKD3 RASSF6 PRKD1	5.23e-05	910	98	11	36736316
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	TPR KRT5 ACOT9 UTP14A PPP1R13L ARPC4 RAD50 CCT6A KHDRBS1 UPF2 AP1M1 DYNC1H1 LRRFIP2	5.25e-05	1257	98	13	36526897
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	TRPC4AP DYNC2H1 TRIP11 RAD50 CCT6A KHDRBS1 PTS SUPT6H DYNC1H1 LRRFIP2	5.44e-05	754	98	10	35906200
Interaction	MOB4 interactions	EPS15 MCC ARPC4 RAD50 CCT6A CCDC88A KHDRBS1	7.53e-06	150	96	7	int:MOB4
Interaction	USO1 interactions	PRKD2 GBF1 UTP14A RUFY1 TRIP11 KHDRBS1 CEP112 PDS5A	8.73e-06	215	96	8	int:USO1
Interaction	DYNC1I2 interactions	PFDN5 RUFY1 DNAH7 TULP3 CCT6A TBC1D1 CCT6B DYNC1H1 NIN	1.16e-05	295	96	9	int:DYNC1I2
Interaction	SNX33 interactions	PRKD2 MCC TULP3 PRKD3 PRKD1	1.35e-05	64	96	5	int:SNX33
Interaction	METTL21A interactions	PFDN5 ARPC4 CCDC88A DYNC1H1	2.53e-05	36	96	4	int:METTL21A
Interaction	PDCD5 interactions	PRKD2 GBF1 TRIM35 UTP14A CCT6A	5.36e-05	85	96	5	int:PDCD5
Interaction	DYNC1I1 interactions	MCC PFDN5 RAD50 CCT6A DYNC1H1 NIN	5.38e-05	139	96	6	int:DYNC1I1
Interaction	PRKY interactions	CLTCL1 RIPK1 DYNC2H1 MTFR1L RAD50 CCT6A	5.60e-05	140	96	6	int:PRKY
Interaction	MYBPC2 interactions	MYH8 TRIP11 TULP3 CCT6A	6.20e-05	45	96	4	int:MYBPC2
Interaction	BACH2 interactions	BACH2 TULP3 CCDC88A AP1M1 NIN	7.05e-05	90	96	5	int:BACH2
Interaction	PCGF3 interactions	PCGF2 PFDN5 BCOR CCT6A DZIP3	7.05e-05	90	96	5	int:PCGF3
Interaction	YWHAE interactions	RALGAPA1 GBF1 NCKAP1 PSMB2 MCC RUFY1 TRIP11 MTFR1L CCDC88A TBC1D4 PAPOLA CEP112 TBC1D1 PRKD1 DYNC1H1 LRRFIP2 NIN	8.30e-05	1256	96	17	int:YWHAE
Interaction	STRN interactions	RALGAPA1 MCC TULP3 CCT6A CCT6B DYNC1H1	9.50e-05	154	96	6	int:STRN
Interaction	METTL21C interactions	CLTCL1 CCDC88A DYNC1H1	9.60e-05	19	96	3	int:METTL21C
Interaction	PLAC8L1 interactions	CLTCL1 CCT6A CCT6B	9.60e-05	19	96	3	int:PLAC8L1
Interaction	UBE2A interactions	TPR KRT5 ACOT9 PSMB2 CCT6A CCT6B AP1M1	1.04e-04	226	96	7	int:UBE2A
Interaction	DCAF5 interactions	PFDN5 TULP3 CCT6A SUPT6H CCT6B	1.06e-04	98	96	5	int:DCAF5
Interaction	HDAC3 interactions	BACH2 IKZF1 BCOR RUFY1 CCT6A CCDC88A PAPOLA DZIP3	1.26e-04	313	96	8	int:HDAC3
Interaction	SH3GL1 interactions	GBF1 PFDN5 ARPC4 TULP3 KHDRBS1 CRTAP	1.34e-04	164	96	6	int:SH3GL1
Interaction	AKTIP interactions	TRIM35 UTP14A UPF2 DZIP3 PDS5A	1.40e-04	104	96	5	int:AKTIP
Interaction	YWHAZ interactions	RALGAPA1 PRKD2 GBF1 NCKAP1 MCC GCH1 BCOR RUFY1 MTFR1L CCDC88A TBC1D4 CEP112 TBC1D1 PRKD1 WDFY3 DYNC1H1 NIN	1.50e-04	1319	96	17	int:YWHAZ
Interaction	DYNC1LI1 interactions	TPR BCOR RUFY1 TULP3 RAD50 DYNC1H1 NIN	1.76e-04	246	96	7	int:DYNC1LI1
Interaction	CCDC185 interactions	BACH2 MCC IKZF1 TBC1D1	1.92e-04	60	96	4	int:CCDC185
Interaction	DISC1 interactions	CEP57L1 TRIP11 ARPC4 CCDC88A KHDRBS1 AP1M1 PRKD1 DYNC1H1 CRTAP	2.09e-04	429	96	9	int:DISC1
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	RUFY1 ZFYVE9 WDFY3	1.32e-04	31	58	3	81
GeneFamily	EF-hand domain containing	EPS15 MCC SCGN DNAH7 NIN	6.77e-04	219	58	5	863
GeneFamily	Dyneins, cytoplasmic	DYNC2H1 DYNC1H1	7.71e-04	13	58	2	538
GeneFamily	Chaperonins	CCT6A CCT6B	1.03e-03	15	58	2	587
GeneFamily	Ring finger proteins	PCGF2 TRIM35 TRIM43 TRIM43B DZIP3	1.86e-03	275	58	5	58
GeneFamily	Phosphodiesterases	PDE4A PDE4C	2.67e-03	24	58	2	681
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM35 TRIM43 TRIM43B	3.52e-03	95	58	3	59
GeneFamily	Ankyrin repeat domain containing	ANKRD66 BCOR PPP1R13L ANKRD53	7.55e-03	242	58	4	403
Coexpression	YANAGIHARA_ESX1_TARGETS	TPR DYNC2H1 PCLO CRTAP	3.90e-06	29	97	4	M1538
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	RALGAPA1 TPR PRKD2 EPS15 NSD1 IKZF1 PFDN5 PRKD3 CCDC88A TBC1D4 KHDRBS1 PAPOLA TBC1D1 DZIP3 AP1M1 PDS5A DYNC1H1 NIN	8.12e-06	1492	97	18	M40023
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	SPATA7 EPS15 DYNC2H1 PCLO CEP57L1 JAKMIP2 RAD50 ZFYVE9 UPF2 SUPT6H WDFY3 POLG2 DYNC1H1	1.92e-06	595	93	13	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5	SPATA7 EPS15 DYNC2H1 CEP57L1 JAKMIP2 IWS1 RAD50 MSR1 ZFYVE9 UPF2 SUPT6H WDFY3	1.92e-05	629	93	12	Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	SPATA7 TPR EPS15 CEP57L1 RAD50 ZFYVE9 UPF2 SUPT6H DZIP3 WDFY3 POLG2	3.58e-05	564	93	11	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR BACH2 NSD1 TRIP11 MSR1 CCT6A CCDC88A NIN	8.06e-09	185	98	8	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR NSD1 TRIP11 CCT6A CCDC88A TBC1D4 CEP112	1.27e-07	176	98	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR BACH2 NSD1 TRIP11 MSR1 CCDC88A NIN	1.60e-07	182	98	7	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3\|TCGA-Thryoid / Sample_Type by Project: Shred V9	DNAH7 MMRN1 TBC1D4 RASSF6 ATP2C2 CLUL1	1.18e-06	154	98	6	4e9203c220a44c70cd7979796a0b461991422257
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue\|TCGA-Thryoid / Sample_Type by Project: Shred V9	DNAH7 MMRN1 TBC1D4 RASSF6 ATP2C2 CLUL1	1.37e-06	158	98	6	8e48952af0831a1fc71ad422e8216b5a92a75991
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue\|TCGA-Thryoid / Sample_Type by Project: Shred V9	DNAH7 MMRN1 TBC1D4 RASSF6 ATP2C2 CLUL1	1.37e-06	158	98	6	e5b55c15a8c99c8d7fc94949f0d3c22e0c3fee7b
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal\|TCGA-Thryoid / Sample_Type by Project: Shred V9	DNAH7 MMRN1 TBC1D4 RASSF6 ATP2C2 CLUL1	1.37e-06	158	98	6	55214d674808584e4d48f8c5e3b8c0e206cb9bb8
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PDE4C PCGF2 CLEC12A MMRN1 ATP2C2 DZIP3	1.90e-06	167	98	6	6c2dade24a88af04b2c90a7e4f8dd7ccea9e94d1
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	PDE4C PCGF2 CLEC12A MMRN1 ATP2C2 DZIP3	1.96e-06	168	98	6	d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 ABCA13 DNAH7 CFAP54 DZIP3	2.57e-06	176	98	6	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	ANKRD66 DYNC2H1 DNAH7 ENO4 CFAP54 DZIP3	3.12e-06	182	98	6	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR NSD1 TRIP11 CCT6A CCDC88A PDS5A	3.32e-06	184	98	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC DNAH7 CFAP54 TBC1D4 PRKD1	4.12e-06	191	98	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CLTCL1 ABCA13 CLEC12A STX3 ATP2C2 WDFY3	4.12e-06	191	98	6	d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CLTCL1 ABCA13 CLEC12A STX3 ATP2C2 WDFY3	4.37e-06	193	98	6	e1855cff9a6bcfda9188b9fdf6c9d698405da990
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 ABCA13 DNAH7 CFAP54 DZIP3	4.37e-06	193	98	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	RALGAPA1 BCOR TRIP11 PDS5A WDFY3 DYNC1H1	4.37e-06	193	98	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	ANKRD66 DYNC2H1 ABCA13 DNAH7 CFAP54 DZIP3	4.37e-06	193	98	6	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	TPR TRIP11 IWS1 RAD50 KHDRBS1 DZIP3	5.21e-06	199	98	6	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TPR PCLO TRIP11 RAD50 KHDRBS1 LRRFIP2	5.21e-06	199	98	6	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKRD66 DNAH7 ENO4 CFAP54 ATP2C2	2.31e-05	154	98	5	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANKRD66 DNAH7 ENO4 CFAP54 ATP2C2	2.31e-05	154	98	5	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BACH2 PRKD3 ENO4 CCDC88A NIN	2.46e-05	156	98	5	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	facs-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF366 CLEC12A MSR1 CCDC88A WDFY3	2.86e-05	161	98	5	45591addc765760db6029ac19e80573373d1d917
ToppCell	facs-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF366 CLEC12A MSR1 CCDC88A WDFY3	2.86e-05	161	98	5	8741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCell	facs-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF366 CLEC12A MSR1 CCDC88A WDFY3	2.86e-05	161	98	5	9cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMGDH KRT5 PDE4C TBC1D4 CEP112	3.51e-05	168	98	5	04a7810f95196a21325356b42084f96c11af5964
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BACH2 IKZF1 JAKMIP2 CCDC88A RASSF6	3.61e-05	169	98	5	203971cceeba150d0e8891c92662545e84c77837
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 ABCA13 DNAH7 CFAP54 DZIP3	3.61e-05	169	98	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	DYNC2H1 ABCA13 DNAH7 CFAP54 DZIP3	3.93e-05	172	98	5	187ae91148d293537afc77e10da2b64302322224
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCOR TULP3 STX3 TBC1D4 CCT6B	4.03e-05	173	98	5	4f849d236ee358ad30ac977745ac43c8e9778e94
ToppCell	droplet-Lung-LUNG-30m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCOR TULP3 STX3 TBC1D4 CCT6B	4.03e-05	173	98	5	39c3b8313354c4c60764597507a2505dcfa4e8c7
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCOR TULP3 STX3 TBC1D4 CCT6B	4.15e-05	174	98	5	e9e4532a474b4b0938a50ff85c9508aca53cd3ae
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC CFAP54 TBC1D4 WDFY3	4.38e-05	176	98	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	UPF2 DZIP3 WDFY3 DHTKD1 DYNC1H1	4.50e-05	177	98	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR NSD1 TRIP11 CCT6A HERC6	4.62e-05	178	98	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC DNAH7 CFAP54 TBC1D4	5.00e-05	181	98	5	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC CFAP54 TBC1D4 WDFY3	5.13e-05	182	98	5	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR NSD1 TRIP11 CCT6A PDS5A	5.13e-05	182	98	5	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR NSD1 TRIP11 CCT6A PDS5A	5.13e-05	182	98	5	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	5.55e-05	185	98	5	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	5.69e-05	186	98	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC IQCN TBC1D4 PRKD1	5.69e-05	186	98	5	3dae539cce15fcf2b1b32e981d7febe94c03c600
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC CFAP54 TBC1D4 WDFY3	5.69e-05	186	98	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC DNAH7 CFAP54 PRKD1	5.69e-05	186	98	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC DNAH7 CFAP54 PRKD1	5.84e-05	187	98	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	ABCA13 PCLO ATP2C2 KCNQ3 PRKD1	5.99e-05	188	98	5	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	5.99e-05	188	98	5	5ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC DNAH7 TBC1D4 WDFY3	6.14e-05	189	98	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	KRT5 NCKAP1 MCC PPP1R13L RASSF6	6.30e-05	190	98	5	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC DNAH7 CFAP54 PRKD1	6.30e-05	190	98	5	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	facs-Pancreas-Endocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIA2 SCGN CCT6A CCDC88A PAPOLA	6.45e-05	191	98	5	b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell	facs-Pancreas\|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNC2H1 TRIM35 PCLO SCGN CCDC88A	6.45e-05	191	98	5	d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell	11.5-Airway-Epithelial-Neuroendocrine\|Airway / Age, Tissue, Lineage and Cell class	PCLO GRIA2 GCH1 SCGN RASSF6	6.45e-05	191	98	5	c1bb3ae5c297f55cdadf5b6e53d5296389d5099e
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	KRT5 NCKAP1 MCC PPP1R13L RASSF6	6.61e-05	192	98	5	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	Bronchial_Brush\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	6.78e-05	193	98	5	3e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DYNC2H1 ABCA13 DNAH7 CFAP54 DZIP3	6.78e-05	193	98	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DYNC2H1 ABCA13 DNAH7 CFAP54 ATP2C2	6.78e-05	193	98	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PFDN5 JAKMIP2 MSR1 CCDC88A TBC1D4	6.78e-05	193	98	5	222829c30ebe47f0ed1e035897e3cd4be10b2a11
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	BACH2 MCC EVC JAKMIP2 PRKD1	6.78e-05	193	98	5	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	ASK440-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	6.95e-05	194	98	5	c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 EVC DNAH7 TBC1D4 PRKD1	6.95e-05	194	98	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	6.95e-05	194	98	5	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	6.95e-05	194	98	5	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 ABCA13 DNAH7 CFAP54 DZIP3	6.95e-05	194	98	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	6.95e-05	194	98	5	a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell	ASK452-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	PDE4C PSMB2 IKZF1 MMRN1 PRKD1	7.12e-05	195	98	5	20f492299a684ac1b7dd1bbc36a533cd6f9a1c93
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 ABCA13 DNAH7 CFAP54 DZIP3	7.12e-05	195	98	5	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.12e-05	195	98	5	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.12e-05	195	98	5	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.12e-05	195	98	5	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	11.5-Distal-Epithelial-Neuroendocrine\|Distal / Age, Tissue, Lineage and Cell class	PCLO GRIA2 GCH1 SCGN RASSF6	7.12e-05	195	98	5	eda6ebe52c48bd6a9044886e75f584f46c2556e7
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 ABCA13 DNAH7 CFAP54 DZIP3	7.12e-05	195	98	5	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 ABCA13 DNAH7 CFAP54 DZIP3	7.12e-05	195	98	5	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	ANKRD66 DNAH7 ENO4 CFAP54 ATP2C2	7.12e-05	195	98	5	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	severe-Myeloid-Immature_Neutrophils_1\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLTCL1 ABCA13 IKZF1 CLEC12A ATP2C2	7.12e-05	195	98	5	becad890a420267ca41e98e61a8da343b51e1945
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 ABCA13 DNAH7 CFAP54	7.12e-05	195	98	5	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.29e-05	196	98	5	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.29e-05	196	98	5	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	PSB-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.47e-05	197	98	5	6865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 ABCA13 DNAH7 DZIP3	7.47e-05	197	98	5	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 ABCA13 DNAH7 DZIP3	7.47e-05	197	98	5	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 ABCA13 DNAH7 DZIP3	7.47e-05	197	98	5	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.47e-05	197	98	5	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	severe-Myeloid-Immature_Neutrophils_1\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CLTCL1 ABCA13 IKZF1 CLEC12A ATP2C2	7.47e-05	197	98	5	9599319dd1f80c81356a8624131566cc76d77d7e
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD66 DYNC2H1 ABCA13 DNAH7 DZIP3	7.47e-05	197	98	5	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.47e-05	197	98	5	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	ANKRD66 JAKMIP2 DNAH7 CFAP54 ATP2C2	7.65e-05	198	98	5	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANKRD66 DYNC2H1 DNAH7 CFAP54 DZIP3	7.65e-05	198	98	5	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	ANKRD66 JAKMIP2 DNAH7 CFAP54 ATP2C2	7.65e-05	198	98	5	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	TRIP11 IWS1 RAD50 CCDC88A KHDRBS1	7.83e-05	199	98	5	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	BAL-Mild-Myeloid-TRAM\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLEC12A MSR1 CCDC88A TBC1D4 CRTAP	7.83e-05	199	98	5	27c63da6b29a1fc57ed2568443ba5029f3cdb186
ToppCell	Biopsy_Control_(H.)-Epithelial-Basal\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	KRT5 GRIA2 SCGN PPP1R13L RASSF6	7.83e-05	199	98	5	6a274a5db02c55bbf31d602b9d5c8394241acdca
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLEC12A MSR1 CCDC88A TBC1D4 CRTAP	7.83e-05	199	98	5	4e518651ff219e163cfd9deb58566df6308aa3f7
ToppCell	BAL-Mild-Myeloid-TRAM-TRAM3-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLEC12A MSR1 CCDC88A TBC1D4 CRTAP	7.83e-05	199	98	5	af167e7a16c3537ce0aa821f608cdcb0c3abc07f
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	TPR TRIP11 RAD50 CCDC88A KHDRBS1	7.83e-05	199	98	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KRT5 PDE4C ABCA13 PPP1R13L ATP2C2	8.02e-05	200	98	5	5f0f67958c9635db53e61f8370a92da6ea3e80fe
ToppCell	COVID-19-COVID-19_Severe-Myeloid-immature_Neutrophil\|COVID-19_Severe / Disease, condition lineage and cell class	CLTCL1 ABCA13 CLEC12A STX3 ATP2C2	8.02e-05	200	98	5	cbe667eda1af222467df8bfa157aa22df488f133
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KRT5 NCKAP1 ABCA13 PCLO RASSF6	8.02e-05	200	98	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANKRD66 JAKMIP2 DNAH7 CFAP54 ATP2C2	8.02e-05	200	98	5	cf191104484bfb2b9f87de416b9453135f8833c1
Drug	1-stearoyl-2-arachidonylglycerol	PRKD2 SCGN PRKD3 PRKD1	4.08e-07	15	97	4	CID006443869
Drug	dyphylline	PDE4A PDE4C PFDN5 TBC1D1	1.15e-05	33	97	4	CID000003182
Drug	2-BDB-TcAMP	PDE4A PFDN5	1.80e-05	2	97	2	CID003081228
Drug	Cyclopenthiazide [742-20-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A	TPR NCKAP1 DYNC2H1 PSMB2 JAKMIP2 STX3 ATP2C2	2.10e-05	196	97	7	4813_DN
Drug	ST021200; Down 200; 10uM; PC3; HT_HG-U133A	RALGAPA1 RIPK1 TRIP11 DNAH7 STX3 ZFYVE9 PDS5A	2.10e-05	196	97	7	7559_DN
Drug	Oxantel pamoate [68813-55-8]; Down 200; 6.6uM; MCF7; HT_HG-U133A	TRPC4AP NCKAP1 UTP14A IGHMBP2 ATP2C2 DZIP3 CCT6B	2.24e-05	198	97	7	5338_DN
Drug	Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A	RALGAPA1 MCC EVC PAPOLA SUPT6H ATP2C2 CCT6B	2.32e-05	199	97	7	4523_DN
Drug	Xylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A	PSMB2 MCC RAD50 ZFYVE9 PAPOLA CCT6B HERC6	2.32e-05	199	97	7	2270_DN
Drug	antibiotic from Streptomyces	PRKD2 GCH1 PRKD3 PRKD1	3.06e-05	42	97	4	CID000005153
Drug	RK-1409B	PRKD2 PRKD3 PRKD1	3.29e-05	15	97	3	CID003036125
Drug	dansyl-DAG	PRKD2 PRKD3 PRKD1	3.29e-05	15	97	3	CID000129493
Drug	Pc 12	PRKD2 DUS4L GRIA2 GCH1 PRKD3 STX3 PRKD1	3.37e-05	211	97	7	CID003036508
Drug	agelasine B	PRKD2 PRKD3 ATP2C2 PRKD1	4.40e-05	46	97	4	CID006439899
Drug	AC1L1JQC	PRKD2 PRKD3 PRKD1	4.88e-05	17	97	3	CID000005157
Drug	daphnoretin	PRKD2 PRKD3 PRKD1	4.88e-05	17	97	3	CID005281406
Drug	vanadyl	PRKD2 PDE4A PDE4C PRKD3 PTS ATP2C2 PRKD1 DYNC1H1	5.10e-05	307	97	8	CID000061671
Drug	8-BDB-TcAMP	PDE4A PFDN5	5.37e-05	3	97	2	CID000164151
Drug	dihydrosterculic acid	PRKD2 PRKD3 PRKD1	5.84e-05	18	97	3	CID000160788
Drug	dipalmitin	PRKD2 PRKD3 PRKD1	5.84e-05	18	97	3	CID000068149
Drug	Cgp-42700	PRKD2 PRKD3 PRKD1	5.84e-05	18	97	3	CID000188390
Drug	TAPP-Br	PRKD2 PRKD3 PRKD1	6.91e-05	19	97	3	CID000160326
Drug	sapintoxin A	PRKD2 PRKD3 PRKD1	6.91e-05	19	97	3	CID000108085
Drug	MDL 27,032	PRKD2 PRKD3 PRKD1	9.43e-05	21	97	3	CID000163812
Drug	KS-619-1	PRKD2 PRKD3 PRKD1	9.43e-05	21	97	3	CID000128369
Drug	K-259-2	PRKD2 PRKD3 PRKD1	9.43e-05	21	97	3	CID006438946
Drug	debromoaplysiatoxin	PRKD2 PRKD3 PRKD1	9.43e-05	21	97	3	CID000002967
Drug	broussochalcone A	PRKD2 PRKD3 PRKD1	9.43e-05	21	97	3	CID006438825
Drug	A0666_sigma	PRKD2 PFDN5 PRKD3 PRKD1	9.59e-05	56	97	4	CID000005680
Drug	orthovanadate	PRKD2 PDE4A PDE4C DUS4L PRKD3 PTS ATP2C2 PRKD1 DYNC1H1	1.01e-04	435	97	9	CID000061672
Drug	R-Te	DYNC2H1 PFDN5 CLEC12A DYNC1H1	1.03e-04	57	97	4	CID000068913
Drug	Piclamilast	PDE4A PDE4C	1.07e-04	4	97	2	DB01791
Drug	RHC 80267	PRKD2 PRKD3 TKFC KCNQ3 PRKD1	1.18e-04	112	97	5	CID000005063
Drug	AC1L4NFY	PRKD2 PRKD3 PRKD1	1.25e-04	23	97	3	CID000160335
Drug	Ro-31-8425	PRKD2 PRKD3 PTS PRKD1	1.26e-04	60	97	4	CID000002404
Drug	AC1OAGFW	CLTCL1 IKZF1 RUFY1 STX3 ZFYVE9 WDFY3	1.38e-04	184	97	6	CID006857352
Drug	17-AAG; Down 200; 1uM; PC3; HT_HG-U133A	PCGF2 PSMB2 BCOR TULP3 CCDC88A HERC6	1.60e-04	189	97	6	1206_DN
Drug	Securinine [5610-40-2]; Up 200; 18.4uM; HL60; HT_HG-U133A	KRT5 TRPC4AP UTP14A ZFYVE9 CEP112 KCNQ3	1.60e-04	189	97	6	2729_UP
Drug	N-acetyldopamine	GCH1 IGHMBP2 ABCC2	1.61e-04	25	97	3	CID000100526
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A	PRKD2 PCGF2 GCH1 TULP3 CCDC88A DHTKD1	1.64e-04	190	97	6	1971_UP
Drug	fura 2	PRKD2 PRKD3 ATP2C2 PRKD1	1.72e-04	65	97	4	CID000057054
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HT_HG-U133A	TPR PCGF2 GCH1 TULP3 ZFYVE9 DZIP3	1.74e-04	192	97	6	1284_UP
Drug	phenylarsine oxide	PRKD2 CLTCL1 GRIA2 PRKD3 KHDRBS1 PTS PRKD1	1.77e-04	275	97	7	CID000004778
Drug	fluo-3	PRKD2 PRKD3 ATP2C2 PRKD1 ABCC2	1.77e-04	122	97	5	CID000104978
Drug	Ibudilast	PDE4A PDE4C	1.78e-04	5	97	2	DB05266
Drug	1,7-naphthyridine	PDE4A PDE4C	1.78e-04	5	97	2	CID000009209
Drug	Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A	PCGF2 BACH2 UTP14A DNAH7 ZFYVE9 IGHMBP2	1.79e-04	193	97	6	3712_DN
Drug	Dizocilpine maleate [77086-22-7]; Up 200; 11.8uM; PC3; HT_HG-U133A	DYNC2H1 TRIP11 TBC1D4 PAPOLA PDS5A WDFY3	1.84e-04	194	97	6	2069_UP
Drug	Iopanoic acid [96-83-3]; Down 200; 7uM; HL60; HT_HG-U133A	TPR ARPC4 STX3 PAPOLA PDS5A WDFY3	1.84e-04	194	97	6	2965_DN
Drug	Cefixime [79350-37-1]; Down 200; 8.8uM; HL60; HT_HG-U133A	GBF1 DYNC2H1 NSD1 CCDC88A PAPOLA PDS5A	1.84e-04	194	97	6	1310_DN
Drug	Buflomedil hydrochloride [35543-24-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A	RIPK1 PSMB2 TBC1D4 ZFYVE9 PAPOLA IGHMBP2	1.84e-04	194	97	6	3274_DN
Drug	Picrotoxinin [17617-45-7]; Down 200; 13.6uM; PC3; HT_HG-U133A	BACH2 CEP112 ATP2C2 CCT6B PDS5A HERC6	1.89e-04	195	97	6	4260_DN
Drug	Sulfapyridine [144-83-2]; Down 200; 16uM; MCF7; HT_HG-U133A	TPR TRPC4AP RIPK1 PSMB2 UTP14A TRIP11	1.89e-04	195	97	6	6799_DN
Drug	Pentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A	UTP14A RAD50 TBC1D4 ZFYVE9 DZIP3 WDFY3	1.89e-04	195	97	6	4396_DN
Drug	Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A	TRPC4AP TULP3 PRKD3 TKFC SUPT6H ATP2C2	1.89e-04	195	97	6	1688_DN
Drug	Baclofen (R,S) [1134-47-0]; Up 200; 18.8uM; PC3; HT_HG-U133A	PDE4A UTP14A NSD1 KHDRBS1 IGHMBP2 ATP2C2	1.94e-04	196	97	6	6313_UP
Drug	Loxapine succinate [27833-64-3]; Down 200; 9uM; MCF7; HT_HG-U133A	PRKD2 PCGF2 PSMB2 ZFYVE9 SUPT6H DZIP3	1.94e-04	196	97	6	5293_DN
Drug	Epitiostanol [2363-58-8]; Down 200; 13uM; HL60; HT_HG-U133A	PCGF2 GBF1 PCLO IKZF1 DZIP3 WDFY3	1.94e-04	196	97	6	2922_DN
Drug	Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; HL60; HT_HG-U133A	PDE4A PCGF2 DYNC2H1 IKZF1 CCT6B PDS5A	1.94e-04	196	97	6	2737_DN
Drug	Pergolide mesylate [66104-23-2]; Up 200; 9.8uM; PC3; HT_HG-U133A	GBF1 NCKAP1 IKZF1 SUPT6H DZIP3 CCT6B	1.94e-04	196	97	6	7271_UP
Drug	Debrisoquin sulfate [581-88-4]; Down 200; 9uM; HL60; HG-U133A	PCGF2 CLTCL1 BCOR CCDC88A KHDRBS1 SUPT6H	1.94e-04	196	97	6	1591_DN
Drug	Parbendazole [14255-87-9]; Down 200; 16.2uM; MCF7; HT_HG-U133A	RIPK1 PCLO DUS4L UTP14A RAD50 IGHMBP2	1.94e-04	196	97	6	3881_DN
Drug	Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; PC3; HT_HG-U133A	PCGF2 NSD1 CCDC88A STX3 SUPT6H ATP2C2	1.94e-04	196	97	6	7278_DN
Drug	AH6809; Down 200; 1uM; PC3; HT_HG-U133A	PCGF2 RIPK1 PCLO CCDC88A CCT6B PRKD1	1.94e-04	196	97	6	7049_DN
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	PDE4A PDE4C PCGF2 DYNC2H1 TULP3 WDFY3	1.94e-04	196	97	6	6203_DN
Drug	Ciprofibrate [52214-84-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A	SPATA7 TRPC4AP TULP3 STX3 SUPT6H LRRFIP2	2.00e-04	197	97	6	6218_DN
Drug	Piperacetazine [3819-00-9]; Down 200; 9.8uM; PC3; HT_HG-U133A	PRKD2 NCKAP1 DUS4L PRKD3 PDS5A HERC6	2.00e-04	197	97	6	5834_DN
Drug	Bendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	PCGF2 GBF1 PSMB2 TULP3 PRKD3 SUPT6H	2.00e-04	197	97	6	3415_DN
Drug	Clebopride maleate [84370-95-6]; Down 200; 8.2uM; MCF7; HT_HG-U133A	PRKD2 RIPK1 STX3 ZFYVE9 CCT6B HERC6	2.00e-04	197	97	6	2646_DN
Drug	Ioversol [87771-40-2]; Down 200; 5uM; MCF7; HT_HG-U133A	EPS15 PDE4C IKZF1 ZFYVE9 SUPT6H IGHMBP2	2.00e-04	197	97	6	3365_DN
Drug	Chloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; HL60; HT_HG-U133A	RALGAPA1 PDE4A DYNC2H1 TRIP11 ZFYVE9 KCNQ3	2.00e-04	197	97	6	3011_UP
Drug	Rilmenidine hemifumarate [54187-04-1]; Down 200; 8.4uM; HL60; HT_HG-U133A	RALGAPA1 GBF1 PCLO UTP14A ZFYVE9 IGHMBP2	2.00e-04	197	97	6	3133_DN
Drug	Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A	PCLO UTP14A IKZF1 GCH1 TULP3 ZFYVE9	2.00e-04	197	97	6	3122_DN
Drug	Aminohippuric acid [61-78-9]; Down 200; 20.6uM; MCF7; HT_HG-U133A	PRKD2 TRPC4AP PCGF2 DYNC2H1 UTP14A ATP2C2	2.00e-04	197	97	6	6453_DN
Drug	ICI 182,780; Down 200; 0.01uM; HL60; HT_HG-U133A	RALGAPA1 PDE4A RIPK1 DYNC2H1 TULP3 ABCC2	2.00e-04	197	97	6	2698_DN
Drug	C15720	PRKD2 PRKD3 PRKD1	2.04e-04	27	97	3	CID000003979
Drug	dichloralurea	EPS15 PFDN5 CRTAP	2.04e-04	27	97	3	CID000008313
Drug	beta-tocopherol	PRKD2 PRKD3 PRKD1	2.04e-04	27	97	3	CID000008989
Drug	ilmofosine	PRKD2 PRKD3 PRKD1	2.04e-04	27	97	3	CID000055008
Drug	pseudohypericin	PRKD2 PRKD3 PRKD1	2.04e-04	27	97	3	CID005281751
Drug	strontium	PRKD2 PRKD3 ATP2C2 PRKD1	2.05e-04	68	97	4	CID000104798
Drug	Deptropine citrate [2169-75-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A	TRPC4AP RIPK1 PCLO NSD1 IGHMBP2 CCT6B	2.05e-04	198	97	6	5543_DN
Drug	Milrinone [78415-72-2]; Up 200; 19uM; PC3; HT_HG-U133A	RALGAPA1 RAD50 STX3 KHDRBS1 SUPT6H DZIP3	2.05e-04	198	97	6	5856_UP
Drug	Gibberellic acid [77-06-5]; Down 200; 11.6uM; HL60; HT_HG-U133A	PCGF2 DUS4L TULP3 TBC1D4 ZFYVE9 PDS5A	2.05e-04	198	97	6	2910_DN
Drug	cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester; Up 200; 100uM; PC3; HG-U133A	TRPC4AP ACOT9 IKZF1 ARPC4 STX3 PDS5A	2.05e-04	198	97	6	664_UP
Drug	Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; PC3; HT_HG-U133A	PDE4A CLTCL1 PSMB2 UTP14A IKZF1 ZFYVE9	2.05e-04	198	97	6	4492_UP
Drug	Ampicillin trihydrate [7177-48-2]; Up 200; 10uM; HL60; HG-U133A	RALGAPA1 PCGF2 CLTCL1 TBC1D4 PDS5A DHTKD1	2.05e-04	198	97	6	2030_UP
Drug	ST021200; Down 200; 10uM; MCF7; HT_HG-U133A	RALGAPA1 UTP14A MCC JAKMIP2 PRKD3 PAPOLA	2.05e-04	198	97	6	7488_DN
Drug	Mephenytoin [50-12-4]; Down 200; 18.4uM; HL60; HT_HG-U133A	PCGF2 DYNC2H1 UTP14A GCH1 IGHMBP2 DZIP3	2.05e-04	198	97	6	6158_DN
Drug	rosiglitazone maleate; Up 200; 10uM; HL60; HG-U133A	RALGAPA1 ACOT9 NSD1 ARPC4 ATP2C2 WDFY3	2.05e-04	198	97	6	369_UP
Drug	Practolol [6673-35-4]; Down 200; 15uM; MCF7; HT_HG-U133A	TRPC4AP IKZF1 TRIP11 ZFYVE9 DZIP3 HERC6	2.11e-04	199	97	6	5664_DN
Drug	chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HG-U133A	RALGAPA1 RIPK1 JAKMIP2 PAPOLA SUPT6H PDS5A	2.11e-04	199	97	6	426_UP
Drug	Isoetharine mesylate salt [7279-75-6]; Up 200; 12uM; MCF7; HT_HG-U133A	PSMB2 UTP14A PRKD3 SUPT6H ABCC2 HERC6	2.11e-04	199	97	6	3451_UP
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; HL60; HT_HG-U133A	PRKD2 IKZF1 TULP3 RAD50 ABCC2 LRRFIP2	2.11e-04	199	97	6	2556_DN
Drug	Thonzonium bromide [553-08-2]; Down 200; 6.8uM; HL60; HT_HG-U133A	PRKD2 PDE4A UTP14A NSD1 TRIP11 PDS5A	2.17e-04	200	97	6	3080_DN
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; HL60; HT_HG-U133A	PDE4A PCGF2 UTP14A IKZF1 ZFYVE9 IGHMBP2	2.17e-04	200	97	6	3062_DN
Drug	bisindolylmaleimide II	PRKD2 PRKD3 PRKD1	2.27e-04	28	97	3	CID000002397
Drug	bisindolylmaleimide V	PRKD2 PRKD3 PRKD1	2.27e-04	28	97	3	CID000002400
Drug	aplysiatoxin	PRKD2 PRKD3 PRKD1	2.27e-04	28	97	3	CID000040465
Drug	HBDDE	PRKD2 PRKD3 PRKD1	2.27e-04	28	97	3	CID000003568
Drug	NCDC	PRKD2 PRKD3 PRKD1	2.27e-04	28	97	3	CID000001583
Disease	Intellectual Disability	RALGAPA1 PCGF2 ACOT9 MCC NSD1 GRIA2 PTS DYNC1H1	9.30e-05	447	94	8	C3714756
Disease	candidiasis (implicated_via_orthology)	PRKD2 PRKD3 PRKD1	3.77e-04	44	94	3	DOID:1508 (implicated_via_orthology)
Disease	Charcot-Marie-Tooth disease type 2	IGHMBP2 DYNC1H1	1.32e-03	17	94	2	cv:C0270914
Disease	unipolar depression	DYNC2H1 ABCA13 PCLO NVL MCC SCGN TRIP11 DNAH7 ENO4 KCNQ3 CRTAP	1.58e-03	1206	94	11	EFO_0003761
Disease	Disproportionate short stature	DYNC2H1 EVC TRIP11	1.93e-03	77	94	3	C0878659
Disease	intrinsic cardiomyopathy (implicated_via_orthology)	CCT6A CCT6B	2.03e-03	21	94	2	DOID:0060036 (implicated_via_orthology)
Disease	triacylglycerol 58:9 measurement	GBF1 CCT6B	2.23e-03	22	94	2	EFO_0010443

Protein segments in the cluster

Peptide	Gene	Start	Entry
IDLFMIEIMEMKHKS	CCT6A	186	P40227
PRNDFQMMIKMHKLT	BACH2	626	Q9BYV9
QMMIKMHKLTSEQLE	BACH2	631	Q9BYV9
QVMLKCMNEEKFHLM	CFAP54	1341	Q96N23
DMSEVEHFMPILMEK	AP1M1	26	Q9BXS5
MELAKMSDMTKLHQA	ANKRD66	1	B4E2M5
ELDMKTKMMEAKFHE	CEP112	256	Q8N8E3
KTSMEVKMQMFQLHG	ACOT9	176	Q9Y305
LMMEKKLHTLEDEQM	ABCA13	716	Q86UQ4
LLKTHVQSRMEKMMD	DHTKD1	551	Q96HY7
IMKMTHSELMEKFLT	BCOR	1566	Q6W2J9
LMALAMKMDLSDIKN	ATP2C2	461	O75185
KFSTLLMMLKDMHDS	NSD1	906	Q96L73
LMMLKDMHDSKTKEQ	NSD1	911	Q96L73
KKVQMHMLDLMSSII	PDS5A	181	Q29RF7
HLKKEEKMTMMAHQY	RASSF6	26	Q6ZTQ3
RSMHSKMLMNIEKVQ	QRICH2	1496	Q9H0J4
KTLDQAIMKFHSMKM	RAD50	1126	Q92878
AIMKFHSMKMEEINK	RAD50	1131	Q92878
FKNILVDEMDMMHAR	IQCN	91	Q9H0B3
KHMDFLSDFEMMLQR	IWS1	521	Q96ST2
DMTLKEVCKMLIHMR	NVL	271	O15381
KMKMFKSQLTLMEHN	ANKRD53	281	Q8N9V6
ALHQKMMELESDMEQ	JAKMIP2	676	Q96AA8
MMELESDMEQFCKIK	JAKMIP2	681	Q96AA8
FVVMEKLHGDMLEMI	PRKD1	656	Q15139
MEASSMRHFEALKLM	PRAMEF17	41	Q5VTA0
MSTLHENIKKQSLMM	MMRN1	546	Q13201
MNMKKSHEVQAMSEL	METTL25	151	Q8N6Q8
AKVDALMDEINFMKM	KRT5	291	P13647
DMGKKLDFLVDMHMQ	KCNQ3	631	O43525
QLKAKLHDMEMERDM	CCDC88A	386	Q3V6T2
ILESPYVMMKKNHEM	GRIA2	421	P42262
YVMMKKNHEMLEGNE	GRIA2	426	P42262
KYDKIEDMAMMTHLH	MYH8	86	P13535
LKSAEEMYEEMMHKT	PCLO	1911	Q9Y6V0
LQEKHAMKQAVMEMM	PFDN5	121	Q99471
MSKHMTLLADLKTMV	PDE4A	546	P27815
MSKHMNLLADLKTMV	PDE4C	501	Q08493
MSEKKAYMLMHETIL	HERC6	646	Q8IVU3
VMEKLHGDMLEMILS	PRKD2	626	Q9BZL6
VMEKLHGDMLEMILS	PRKD3	651	O94806
DMMGILKDFHRMKQS	MTFR1L	241	Q9H019
TMKEMMHISKLKDFL	POLG2	461	Q9UHN1
VDAQKLMDVTNFMHM	ABCC2	426	Q92887
KENEMMKSHVMDQAI	IKZF1	301	Q13422
KLDMKEIHTYMEMFQ	NPIPA2	191	E9PIF3
EAENKFLVMKMMIQE	DZIP3	156	Q86Y13
MEMTNSHLAKRLEKM	LRRFIP2	696	Q9Y608
ELGKMMNTIIFHTKM	NCKAP1	511	Q9Y2A7
QEVFMEHMSNMEKRI	MSR1	111	P21757
AMTVMHLAKFLRNKM	PCGF2	171	P35227
MFEVDMKIAAMHVKR	PAPOLA	476	P51003
DKFELMMESHQLMIK	DYNC2H1	1016	Q8NCM8
MMESHQLMIKDQIEV	DYNC2H1	1021	Q8NCM8
ELMAMKEEMAELKAQ	MCC	621	P23508
FLLKHPDDEMMKRNM	CRTAP	171	O75718
IMRHMDSAKETLLKM	DNAH7	316	Q8WXX0
MEHIKAAMEMVPVLK	DMGDH	346	Q9UI17
MLMEMQKHINKIIEM	ENO4	316	A6NNW6
SKMLKMQMLEDEDDL	DYNC1H1	4341	Q14204
SMREHLKFQMEMYIK	GBF1	486	Q92538
HAMEEVKKFLVPDMM	KHDRBS1	246	Q07666
QMSMEHQELLKQMKE	CEP57L1	336	Q8IYX8
HLMYMMEKITSRQEK	DUS4L	281	O95620
SMQMKLMEMKDLENH	EPS15	491	P42566
EKHMMFIQIFKMCLL	EVC	231	P57679
FLHMLMKLGTDDTVM	SCGN	41	O76038
AMKHMDLKQMELDTA	PPP1R13L	21	Q8WUF5
VLLEQMMRKKQAMHL	UPF2	726	Q9HAU5
LQMEMKEDDVSFLMK	TRIM35	241	Q9UPQ4
LKEMYQELMEMCHKP	TRIM43	226	Q96BQ3
IDLFMVEIMEMKHKL	CCT6B	186	Q92526
PQSMKIMHEIMYKLE	TRPC4AP	376	Q8TEL6
HDQERQEMMSKLLAM	NIN	976	Q8N4C6
QEMMSKLLAMENIHK	NIN	981	Q8N4C6
EERANLMHMMKLSIK	RUFY1	111	Q96T51
NMMMDLLHLHEKFFR	PNLDC1	256	Q8NA58
HDEMVIVKDIDMFSM	GCH1	126	P30793
VQMKDDHDKMFKMSE	PSMB2	26	P49721
VMEYMEKGNLMHVLK	RIPK1	91	Q13546
SSIKELHDMFMDIAM	STX3	206	Q13277
EIEKILCHKFMRFMM	ARPC4	81	P59998
FNIEMKSKMKAHTMA	CLTCL1	91	P53675
ASMFHVTLKIEMKKM	CLEC12A	61	Q5QGZ9
IMMERKEKEHTNLMS	CLUL1	61	Q15846
HNINFKQAEKMMETM	SUPT6H	1336	Q7KZ85
MAQKIMKMIHGDYIE	SUN5	181	Q8TC36
HMTQKEQEEKLYMML	WDFY3	41	Q8IZQ1
MKNHMFSIQIMKKPE	RALGAPA1	1936	Q6GYQ0
MAQHEELMKKTETMN	TPR	1256	P12270
AMIVEFMASKKMQLE	IGHMBP2	731	P38935
EEEAFKMLKFLMFDM	TBC1D1	906	Q86TI0
NNHDMELSTLKIMEM	SPATA7	576	Q9P0W8
IEKARMMERMSLKHQ	UTP14A	286	Q9BVJ6
HMSEEQAFEMLKFLM	TBC1D4	1021	O60343
GKLDMKEIHTYMKMF	NPIPB2	186	A6NJ64
MQKEMKMIKDEDVHF	ZNF366	1	Q8N895
MMLREKEFECHSMKE	TRIP11	1491	Q15643
LKEMYQELMEMCHKP	TRIM43B	226	A6NCK2
MATADEIVKLMLDHM	TKFC	231	Q3LXA3
MNLADLKKYMEEAIM	PTS	71	Q03393
FHEEMMKMRQAKLDY	TULP3	16	O75386
EMMKAMNKSNEHVLA	ZFYVE9	1146	O95405
IMNKFKVLMEIQDLM	L1TD1	51	Q5T7N2