Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THSD4 COL6A6 TFPI2 EFEMP1 MEGF9 LTBP2 BMPER MUC5AC MUC6	3.95e-05	188	173	9	GO:0005201
GeneOntologyMolecularFunction	latrotoxin receptor activity	ADGRL1 ADGRL2	7.46e-05	2	173	2	GO:0016524
GeneOntologyMolecularFunction	epidermal growth factor receptor activity	ERBB4 EFEMP1	4.43e-04	4	173	2	GO:0005006
GeneOntologyMolecularFunction	cytokine binding	IL13RA1 CCR9 ITGB1 ITGB3 LTBP3 TNFRSF1A TNFRSF1B	4.45e-04	157	173	7	GO:0019955
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	USP9Y USP20 UCHL5 USP12 TNFAIP3 USP33	4.78e-04	114	173	6	GO:0004843
GeneOntologyMolecularFunction	C-X3-C chemokine binding	ITGB1 ITGB3	7.34e-04	5	173	2	GO:0019960
GeneOntologyMolecularFunction	collagen binding involved in cell-matrix adhesion	ITGA10 ITGB1	7.34e-04	5	173	2	GO:0098639
GeneOntologyMolecularFunction	deubiquitinase activity	USP9Y USP20 UCHL5 USP12 TNFAIP3 USP33	7.45e-04	124	173	6	GO:0101005
GeneOntologyMolecularFunction	death receptor activity	TNFRSF10B TNFRSF1A TNFRSF1B	7.58e-04	21	173	3	GO:0005035
GeneOntologyCellularComponent	extracellular matrix	THSD4 ADAMTSL1 COL6A6 TFPI2 ITGB1 EFEMP1 MEGF9 ADAMTS7 SPOCK3 LTBP2 LTBP3 LGR6 BMPER ADAMTS14 MUC5AC MUC6 CDH13	4.14e-05	656	176	17	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	THSD4 ADAMTSL1 COL6A6 TFPI2 ITGB1 EFEMP1 MEGF9 ADAMTS7 SPOCK3 LTBP2 LTBP3 LGR6 BMPER ADAMTS14 MUC5AC MUC6 CDH13	4.30e-05	658	176	17	GO:0030312
GeneOntologyCellularComponent	integrin alpha10-beta1 complex	ITGA10 ITGB1	7.05e-05	2	176	2	GO:0034680
GeneOntologyCellularComponent	cerebellar climbing fiber to Purkinje cell synapse	ADGRB3 ITGB1 PLXNC1	9.21e-05	11	176	3	GO:0150053
GeneOntologyCellularComponent	integrin alpha9-beta1 complex	ITGB1 ITGB3	2.10e-04	3	176	2	GO:0034679
GeneOntologyCellularComponent	tumor necrosis factor receptor superfamily complex	TNFRSF1A TNFRSF1B	4.18e-04	4	176	2	GO:0002947
GeneOntologyCellularComponent	receptor complex	IL13RA1 ERBB4 GFRAL ITGA10 GRIK3 ITGB1 LRP1B ITGB3 TRBV29-1 PIGR PLXNC1 TNFRSF1A TNFRSF1B TRAV22	4.20e-04	581	176	14	GO:0043235
GeneOntologyCellularComponent	external side of plasma membrane	SIGLEC12 IL13RA1 GFRAL CD244 CCR9 ITGA10 ADAM29 ITGB1 ITGB3 MICB SCART1 CDH13 GP2	4.70e-04	519	176	13	GO:0009897
GeneOntologyCellularComponent	perinuclear region of cytoplasm	CABP7 INHBA ARFGEF2 ITGB1 USP20 RYR1 TG PACS1 IGF2R SYNJ1 CCDC78 ATXN10 HSP90AB2P TNFRSF1B TNKS2 CDH13 HERC5 USP33	9.31e-04	934	176	18	GO:0048471
GeneOntologyCellularComponent	asymmetric, glutamatergic, excitatory synapse	ADGRB3 ITGB1 PLXNC1	1.04e-03	24	176	3	GO:0098985
Domain	GPS	ADGRB3 ADGRG1 ADGRL1 PKDREJ ADGRL2 ADGRF1	6.72e-07	34	175	6	SM00303
Domain	RCC1	RCBTB2 ALS2 RCBTB1 HERC1 HERC5	9.44e-07	20	175	5	PF00415
Domain	GPS	ADGRB3 ADGRG1 ADGRL1 PKDREJ ADGRL2 ADGRF1	1.13e-06	37	175	6	IPR000203
Domain	RCC1_1	RCBTB2 ALS2 RCBTB1 HERC1 HERC5	1.23e-06	21	175	5	PS00625
Domain	RCC1_2	RCBTB2 ALS2 RCBTB1 HERC1 HERC5	1.23e-06	21	175	5	PS00626
Domain	RCC1_3	RCBTB2 ALS2 RCBTB1 HERC1 HERC5	1.23e-06	21	175	5	PS50012
Domain	-	RCBTB2 ALS2 RCBTB1 HERC1 HERC5	1.58e-06	22	175	5	2.130.10.30
Domain	Reg_chr_condens	RCBTB2 ALS2 RCBTB1 HERC1 HERC5	1.58e-06	22	175	5	IPR000408
Domain	TSP_1	THSD4 ADAMTSL1 THSD7A ADGRB3 SEMA5A ADAMTS7 ADAMTS14	2.00e-06	63	175	7	PF00090
Domain	RCC1/BLIP-II	RCBTB2 ALS2 RCBTB1 HERC1 HERC5	2.00e-06	23	175	5	IPR009091
Domain	TSP1	THSD4 ADAMTSL1 THSD7A ADGRB3 SEMA5A ADAMTS7 ADAMTS14	2.48e-06	65	175	7	SM00209
Domain	TSP1_rpt	THSD4 ADAMTSL1 THSD7A ADGRB3 SEMA5A ADAMTS7 ADAMTS14	2.48e-06	65	175	7	IPR000884
Domain	TSP1	THSD4 ADAMTSL1 THSD7A ADGRB3 SEMA5A ADAMTS7 ADAMTS14	2.48e-06	65	175	7	PS50092
Domain	GPS	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	1.76e-05	35	175	5	PF01825
Domain	GPS	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	2.03e-05	36	175	5	PS50221
Domain	PLAC	THSD4 ADAMTSL1 ADAMTS7 ADAMTS14	2.59e-05	19	175	4	PS50900
Domain	PLAC	THSD4 ADAMTSL1 ADAMTS7 ADAMTS14	2.59e-05	19	175	4	IPR010909
Domain	Ribosomal_S27e	RPS27 RPS27L	8.73e-05	2	175	2	IPR000592
Domain	Ribosomal_S27e_Zn-bd_dom	RPS27 RPS27L	8.73e-05	2	175	2	IPR023407
Domain	ASH	ASPM HYDIN	8.73e-05	2	175	2	IPR031549
Domain	Ribosomal_S27e	RPS27 RPS27L	8.73e-05	2	175	2	PD004466
Domain	RIBOSOMAL_S27E	RPS27 RPS27L	8.73e-05	2	175	2	PS01168
Domain	Ribosomal_S27e	RPS27 RPS27L	8.73e-05	2	175	2	PF01667
Domain	ASH	ASPM HYDIN	8.73e-05	2	175	2	PF15780
Domain	-	RPS27 RPS27L	8.73e-05	2	175	2	2.20.25.100
Domain	TNFR	TNFRSF10B MEGF9 TNFRSF1A TNFRSF1B	9.48e-05	26	175	4	SM00208
Domain	7tm_2	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	1.03e-04	50	175	5	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	1.03e-04	50	175	5	PS00650
Domain	GAIN_dom_N	ADGRB3 ADGRL1 ADGRL2	1.26e-04	11	175	3	IPR032471
Domain	GAIN	ADGRB3 ADGRL1 ADGRL2	1.26e-04	11	175	3	PF16489
Domain	C8	BMPER MUC5AC MUC6	1.67e-04	12	175	3	PF08742
Domain	TIL	BMPER MUC5AC MUC6	1.67e-04	12	175	3	PF01826
Domain	RA	RALGDS RGL3 RASSF7 RASSF8	1.92e-04	31	175	4	SM00314
Domain	Unchr_dom_Cys-rich	BMPER MUC5AC MUC6	2.16e-04	13	175	3	IPR014853
Domain	C8	BMPER MUC5AC MUC6	2.16e-04	13	175	3	SM00832
Domain	ARM-like	SETX RTTN ARFGEF2 HEATR5A USP9Y ASPM ZER1 ATXN10 PRKDC XPOT	2.38e-04	270	175	10	IPR011989
Domain	GPCR_2_secretin-like	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	2.46e-04	60	175	5	IPR000832
Domain	GPCR_2-like	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	2.46e-04	60	175	5	IPR017981
Domain	TNFR/NGFR_Cys_rich_reg	TNFRSF10B MEGF9 TNFRSF1A TNFRSF1B	2.46e-04	33	175	4	IPR001368
Domain	Latrophilin	ADGRL1 ADGRL2	2.60e-04	3	175	2	PF02354
Domain	GPCR_2_latrophilin_rcpt_C	ADGRL1 ADGRL2	2.60e-04	3	175	2	IPR003334
Domain	G_PROTEIN_RECEP_F2_4	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	2.65e-04	61	175	5	PS50261
Domain	TIL_dom	BMPER MUC5AC MUC6	2.73e-04	14	175	3	IPR002919
Domain	RA	RALGDS RGL3 RASSF7 RASSF8	3.47e-04	36	175	4	PF00788
Domain	RA	RALGDS RGL3 RASSF7 RASSF8	3.86e-04	37	175	4	PS50200
Domain	VWF_type-D	BMPER MUC5AC MUC6	4.14e-04	16	175	3	IPR001846
Domain	VWFD	BMPER MUC5AC MUC6	4.14e-04	16	175	3	PS51233
Domain	VWD	BMPER MUC5AC MUC6	4.14e-04	16	175	3	SM00216
Domain	VWD	BMPER MUC5AC MUC6	4.14e-04	16	175	3	PF00094
Domain	-	TG SPOCK3 EPCAM	4.99e-04	17	175	3	4.10.800.10
Domain	Thyroglobulin_1	TG SPOCK3 EPCAM	4.99e-04	17	175	3	IPR000716
Domain	THYROGLOBULIN_1_1	TG SPOCK3 EPCAM	4.99e-04	17	175	3	PS00484
Domain	TY	TG SPOCK3 EPCAM	4.99e-04	17	175	3	SM00211
Domain	THYROGLOBULIN_1_2	TG SPOCK3 EPCAM	4.99e-04	17	175	3	PS51162
Domain	Thyroglobulin_1	TG SPOCK3 EPCAM	4.99e-04	17	175	3	PF00086
Domain	-	ITGB1 ITGB3	5.17e-04	4	175	2	1.20.5.630
Domain	N-RASSF	RASSF7 RASSF8	5.17e-04	4	175	2	IPR033593
Domain	GPCR_2_extracellular_dom	ADGRB3 ADGRL1 ADGRL2 ADGRF1	5.23e-04	40	175	4	IPR001879
Domain	RA_dom	RALGDS RGL3 RASSF7 RASSF8	5.23e-04	40	175	4	IPR000159
Domain	G_PROTEIN_RECEP_F2_1	ADGRB3 ADGRL1 ADGRL2 ADGRF1	5.23e-04	40	175	4	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRB3 ADGRL1 ADGRL2 ADGRF1	5.23e-04	40	175	4	PS50227
Domain	EGF_1	ADAM29 ITGB1 LRP1B ITGB3 EFEMP1 MEGF9 LTBP2 LTBP3 GP2	6.90e-04	255	175	9	PS00022
Domain	PSI	SEMA5A ITGB1 ITGB3 PLXNC1	7.55e-04	44	175	4	IPR016201
Domain	EGF-like_CS	ADAM29 ITGB1 LRP1B ITGB3 EFEMP1 MEGF9 LTBP2 LTBP3 GP2	8.14e-04	261	175	9	IPR013032
Domain	Gal_Lectin	ADGRL1 ADGRL2	8.57e-04	5	175	2	PF02140
Domain	GPCR_2_latrophilin	ADGRL1 ADGRL2	8.57e-04	5	175	2	IPR003924
Domain	Lectin_gal-bd_dom	ADGRL1 ADGRL2	8.57e-04	5	175	2	IPR000922
Domain	SUEL_LECTIN	ADGRL1 ADGRL2	8.57e-04	5	175	2	PS50228
Domain	PSI	SEMA5A ITGB1 ITGB3 PLXNC1	8.94e-04	46	175	4	SM00423
Domain	VWFA	COL6A6 ITGA10 ITGB1 ITGB3 INTS14	1.04e-03	82	175	5	PS50234
Domain	TNFR_c6	TNFRSF10B TNFRSF1A TNFRSF1B	1.09e-03	22	175	3	PF00020
Domain	VWA	COL6A6 ITGA10 ITGB1 ITGB3 INTS14	1.16e-03	84	175	5	SM00327
Domain	-	RTTN ARFGEF2 HEATR5A ASPM ZER1 ATXN10 PRKDC XPOT	1.19e-03	222	175	8	1.25.10.10
Domain	ADAM_spacer1	THSD4 ADAMTS7 ADAMTS14	1.25e-03	23	175	3	IPR010294
Domain	ADAM_spacer1	THSD4 ADAMTS7 ADAMTS14	1.25e-03	23	175	3	PF05986
Domain	DUSP	USP20 USP33	1.28e-03	6	175	2	PF06337
Domain	Integrin_b_cyt	ITGB1 ITGB3	1.28e-03	6	175	2	SM01241
Domain	Integrin_b_cyt	ITGB1 ITGB3	1.28e-03	6	175	2	PF08725
Domain	DUSP	USP20 USP33	1.28e-03	6	175	2	SM00695
Domain	Integrin_bsu_cyt_dom	ITGB1 ITGB3	1.28e-03	6	175	2	IPR014836
Domain	ARM-type_fold	RTTN ARFGEF2 HEATR5A USP9Y ASPM ZER1 ATXN10 PRKDC NUP188 XPOT	1.39e-03	339	175	10	IPR016024
Domain	Peptidase_M12B_ADAM-TS	ADAMTSL1 ADAMTS7 ADAMTS14	1.42e-03	24	175	3	IPR013273
Domain	Integrin_dom	ITGA10 ITGB1 ITGB3	1.60e-03	25	175	3	IPR032695
Domain	HormR	ADGRB3 ADGRL1 ADGRL2	1.60e-03	25	175	3	SM00008
Domain	TB	LTBP2 LTBP3	1.78e-03	7	175	2	PF00683
Domain	DUSP	USP20 USP33	1.78e-03	7	175	2	PS51283
Domain	Integrin_B_tail	ITGB1 ITGB3	1.78e-03	7	175	2	SM01242
Domain	Integrin_bsu_tail	ITGB1 ITGB3	1.78e-03	7	175	2	IPR012896
Domain	-	USP20 USP33	1.78e-03	7	175	2	3.30.2230.10
Domain	CBM21_dom	PPP1R3G PPP1R3C	1.78e-03	7	175	2	IPR005036
Domain	CBM21	PPP1R3G PPP1R3C	1.78e-03	7	175	2	PS51159
Domain	Pept_C19_DUSP	USP20 USP33	1.78e-03	7	175	2	IPR006615
Domain	Integrin_B_tail	ITGB1 ITGB3	1.78e-03	7	175	2	PF07965
Domain	CBM_21	PPP1R3G PPP1R3C	1.78e-03	7	175	2	PF03370
Domain	cEGF	LRP1B EFEMP1 LTBP3	1.79e-03	26	175	3	PF12662
Domain	cEGF	LRP1B EFEMP1 LTBP3	1.79e-03	26	175	3	IPR026823
Domain	HRM	ADGRB3 ADGRL1 ADGRL2	2.23e-03	28	175	3	PF02793
Domain	-	LTBP2 LTBP3	2.36e-03	8	175	2	3.90.290.10
Domain	INB	ITGB1 ITGB3	2.36e-03	8	175	2	SM00187
Domain	Integrin_bsu_VWA	ITGB1 ITGB3	2.36e-03	8	175	2	IPR002369
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD4 ADAMTSL1 THSD7A SEMA5A ADAMTS7 ADAMTS14 MUC5AC MUC6	3.28e-07	68	139	8	M27303
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTSL1 THSD7A SEMA5A ADAMTS7 ADAMTS14	2.06e-06	39	139	6	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTSL1 THSD7A SEMA5A ADAMTS7 ADAMTS14	2.06e-06	39	139	6	MM15165
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTSL1 THSD7A SEMA5A ADAMTS7 ADAMTS14 MUC5AC MUC6	1.20e-05	109	139	8	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THSD4 ADAMTSL1 THSD7A SEMA5A ADAMTS7 ADAMTS14 MUC5AC MUC6	1.37e-05	111	139	8	M27416
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	ITGB1 ITGB3 EFEMP1 LTBP2 LTBP3	2.93e-05	37	139	5	M27134
Pathway	REACTOME_ELASTIC_FIBRE_FORMATION	ITGB1 ITGB3 EFEMP1 LTBP2 LTBP3	6.91e-05	44	139	5	M26969
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD4 ADAMTSL1 THSD7A SEMA5A ADAMTS7 ADAMTS14 MUC5AC MUC6	8.48e-05	143	139	8	M27275
Pathway	REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS	ITGB1 ITGB3 UCHL5 LTBP2 LTBP3	9.54e-05	47	139	5	M646
Pathway	REACTOME_DISEASES_OF_METABOLISM	THSD4 ADAMTSL1 THSD7A SEMA5A PPP1R3C ADAMTS7 ADAMTS14 PC MUC5AC MUC6	1.85e-04	250	139	10	M27554
Pathway	REACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES	ITGB1 ITGB3 LTBP2 LTBP3	2.63e-04	32	139	4	MM14854
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLII RTTN OBSCN ARFGEF2 ADGRL1 CLDN3 RASSF7 RYR1 IGF2R SYNJ1 ADAMTS7 ZNF592 ZMIZ2 BANP HELZ2 ZER1 LTBP3 PRKDC NUP188 TNFAIP3 HERC1 PC ARHGAP21 TOP3A	3.40e-09	1105	180	24	35748872
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLII KRT83 ADGRB3 ARFGEF2 AIRE USP9Y LRP1B EEF2 UBE2O EFEMP1 ZNF660 SYNJ1 MEGF9 ZNF592 RCBTB1 MIB1 LTBP3 ATXN10 PRKDC TNKS2 PC ARHGAP21 USP33 XPOT	5.94e-08	1285	180	24	35914814
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THSD4 ADAMTSL1 THSD7A ADGRB3 SEMA5A ADAMTS7 ADAMTS14	1.31e-07	75	180	7	20637190
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB3 ADGRG1 ADGRL1 ADGRL2 ADGRF1	7.41e-07	33	180	5	25713288
Pubmed	Defects in cell-mediated immunity affect chronic, but not innate, resistance of mice to Mycobacterium avium infection.	PRKDC TNFRSF1A TNFRSF1B	1.35e-06	5	180	3	9144497
Pubmed	The importance of IL-1 beta and TNF-alpha, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis.	PRKDC TNFRSF1A TNFRSF1B	1.35e-06	5	180	3	12133972
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	CCR9 OBSCN ARFGEF2 RPS27L CDC45 YEATS2 EEF2 IGF2R ATXN10 PRKDC NUP188 ALDH1A3 MUC5AC XPOT	1.62e-06	564	180	14	21565611
Pubmed	NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-κB.	PRKDC TNFRSF1A TNFRSF1B	2.70e-06	6	180	3	24892805
Pubmed	M-CSF mediates TNF-induced inflammatory osteolysis.	PRKDC TNFRSF1A TNFRSF1B	2.70e-06	6	180	3	16294221
Pubmed	Production of IFN-gamma by CD4 T cells is essential for resolving ehrlichia infection.	PRKDC TNFRSF1A TNFRSF1B	1.12e-05	9	180	3	15153508
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ERBB4 SETX ALS2 RPS27 STIL RASSF7 FSIP2 SYNJ1 IKBKE SYNE2 TNFAIP3 CGNL1 RASSF8 KIF13A PC ARHGAP21	1.16e-05	861	180	16	36931259
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRB3 ADGRL1 ADGRL2 ADGRF1	1.49e-05	29	180	4	15203201
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ERBB4 ITGB1 LRP1B ITGB3 PIGR TNFRSF1A	1.49e-05	101	180	6	23382219
Pubmed	Graft-versus-leukemia (GVL) against mouse blast-crisis chronic myelogenous leukemia (BC-CML) and chronic-phase chronic myelogenous leukemia (CP-CML): shared mechanisms of T cell killing, but programmed death ligands render CP-CML and not BC-CML GVL resistant.	TNFRSF10B TNFRSF1A TNFRSF1B	1.59e-05	10	180	3	21768400
Pubmed	Human gingiva transcriptome during wound healing.	SFRP4 HK3 INHBA GRIK3 ITGB3 LGR6	2.07e-05	107	180	6	28005267
Pubmed	Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.	THSD4 ERBB4 LRP1B CDH13	2.53e-05	33	180	4	24159190
Pubmed	Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	1849278
Pubmed	The p55 TNF-alpha receptor plays a critical role in T cell alloreactivity.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	10623807
Pubmed	TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	9551964
Pubmed	Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	10779546
Pubmed	Divergent relationships among soluble tumor necrosis factor-alpha receptors 1 and 2, insulin resistance, and endothelial function.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	16732051
Pubmed	Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	12786601
Pubmed	TNF receptor type 1 and TNF receptor type 2 mRNA expression was not associated with coronary artery disease in a group of Iranian Turks.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	30793619
Pubmed	Modulation of allergic inflammation in mice deficient in TNF receptors.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	11076794
Pubmed	TNFalpha transport across the blood-brain barrier is abolished in receptor knockout mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	11922661
Pubmed	Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	10500078
Pubmed	Increased sensitivity of T lymphocytes to tumor necrosis factor receptor 1 (TNFR1)- and TNFR2-mediated apoptosis in HIV infection: relation to expression of Bcl-2 and active caspase-8 and caspase-3.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	11861282
Pubmed	Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	25288570
Pubmed	Sources of alveolar soluble TNF receptors during acute lung injury of different etiologies.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	21512145
Pubmed	Differential regulation of TNF receptors in maternal leukocytes is associated with severe preterm preeclampsia.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	25034210
Pubmed	Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	24569452
Pubmed	Role of the tumor necrosis factor receptor 2 (TNFR2) in cerebral malaria in mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	12218076
Pubmed	Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	33270628
Pubmed	Deficiency in tumor necrosis factor alpha activity does not impair early protective Th1 responses against blood-stage malaria.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	10225939
Pubmed	Mechanisms of sex differences in TNFR2-mediated cardioprotection.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	18824767
Pubmed	T-cadherin enhances cell-matrix adhesiveness by regulating beta1 integrin trafficking in cutaneous squamous carcinoma cells.	ITGB1 CDH13	2.66e-05	2	180	2	17573778
Pubmed	β3 integrin is dispensable for conditioned fear and hebbian forms of plasticity in the hippocampus.	ITGB1 ITGB3	2.66e-05	2	180	2	22748100
Pubmed	Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	16277675
Pubmed	Genetic polymorphisms of tumour necrosis factor receptor superfamily 1A and 1B affect responses to infliximab in Japanese patients with Crohn's disease.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	18248655
Pubmed	TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	21850048
Pubmed	Tumor Necrosis Factor (TNF) Receptor Superfamily Member 1b on CD8+ T Cells and TNF Receptor Superfamily Member 1a on Non-CD8+ T Cells Contribute Significantly to Upper Genital Tract Pathology Following Chlamydial Infection.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	25552370
Pubmed	Circulating TNF receptors predict cardiovascular disease in patients with chronic kidney disease.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	28489742
Pubmed	Neddylation modification of ribosomal protein RPS27L or RPS27 by MDM2 or NEDP1 regulates cancer cell survival.	RPS27 RPS27L	2.66e-05	2	180	2	32779270
Pubmed	Kinetic characterization of recombinant mouse retinal dehydrogenase types 3 and 4 for retinal substrates.	ALDH8A1 ALDH1A3	2.66e-05	2	180	2	19766701
Pubmed	Distinct contributions of TNF receptor 1 and 2 to TNF-induced glomerular inflammation in mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	23869211
Pubmed	[Expression of tumor necrosis factor-alpha (TNF-alpha) on peritoneal fluid mononuclear cells in women with endometriosis].	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	18510047
Pubmed	Potential Role of Soluble TNF-α Receptors in Diagnosis of Patients with Chronic Kidney Disease.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	28667032
Pubmed	C1q-TNF-related protein-9, a novel cardioprotetcive cardiokine, requires proteolytic cleavage to generate a biologically active globular domain isoform.	C1QTNF9B C1QTNF9	2.66e-05	2	180	2	25783894
Pubmed	Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	7990930
Pubmed	TNFR2 increases the sensitivity of ligand-induced activation of the p38 MAPK and NF-κB pathways and signals TRAF2 protein degradation in macrophages.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	24378531
Pubmed	TNF-α type 2 receptor mediates renal inflammatory response to chronic angiotensin II administration with high salt intake in mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	23389459
Pubmed	C1q/TNF-related proteins, a family of novel adipokines, induce vascular relaxation through the adiponectin receptor-1/AMPK/eNOS/nitric oxide signaling pathway.	C1QTNF9B C1QTNF9	2.66e-05	2	180	2	21836066
Pubmed	Characteristic elevation of soluble TNF receptor II : I ratio in macrophage activation syndrome with systemic juvenile idiopathic arthritis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	28815559
Pubmed	Hyper innate responses in neonates lead to increased morbidity and mortality after infection.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	18490660
Pubmed	Circulating TNF receptors are significant prognostic biomarkers for idiopathic membranous nephropathy.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	25098821
Pubmed	Clinicopathological features of superficial non-ampurally duodenal epithelial tumor; gastric phenotype of histology correlates to higher malignant potency.	MUC5AC MUC6	2.66e-05	2	180	2	28321513
Pubmed	Dissection of antiviral and immune regulatory functions of tumor necrosis factor receptors in a chronic lymphocytic choriomeningitis virus infection.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	15047807
Pubmed	Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	8910423
Pubmed	Tumor necrosis factor-alpha receptor p75 is required in ischemia-induced neovascularization.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	17261656
Pubmed	Characterization of TNF receptor subtype expression and signaling on pulmonary endothelial cells in mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	21378027
Pubmed	Tumor necrosis factor receptor 1 and 2 proteins are differentially regulated during Wallerian degeneration of mouse sciatic nerve.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	15698630
Pubmed	The tumor necrosis factor receptor stalk regions define responsiveness to soluble versus membrane-bound ligand.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	22547679
Pubmed	A Straightforward Method for 3D Visualization of B Cell Clusters and High Endothelial Venules in Lymph Nodes Highlights Differential Roles of TNFRI and -II.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	34234786
Pubmed	A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	10875917
Pubmed	TNF-α Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	36012570
Pubmed	Targeted deletion of C1q/TNF-related protein 9 increases food intake, decreases insulin sensitivity, and promotes hepatic steatosis in mice.	C1QTNF9B C1QTNF9	2.66e-05	2	180	2	24473438
Pubmed	Role of TNF-{alpha} signaling in regeneration of cardiotoxin-injured muscle.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	16079187
Pubmed	Are alsin and spartin novel interaction partners?	SPART ALS2	2.66e-05	2	180	2	22982304
Pubmed	Inhibition of eosinophilic inflammation in allergen-challenged TNF receptor p55/p75--and TNF receptor p55-deficient mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	11245629
Pubmed	Adipose-derived factor CTRP9 attenuates vascular smooth muscle cell proliferation and neointimal formation.	C1QTNF9B C1QTNF9	2.66e-05	2	180	2	22972916
Pubmed	Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.	ITGB1 ITGB3	2.66e-05	2	180	2	22511753
Pubmed	Soluble tumour necrosis factor receptors sTNFR1 and sTNFR2 are produced at sites of inflammation and are markers of arthritis activity in Behçet's disease.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	18415772
Pubmed	Increased concentration of plasma TNFR1 and TNFR2 in paediatric lupus nephritis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	26854079
Pubmed	Association of genetic variations of genes encoding thrombospondin, type 1, domain-containing 4 and 7A with low bone mineral density in Japanese women with osteoporosis.	THSD4 THSD7A	2.66e-05	2	180	2	18488137
Pubmed	Receptors for tumor necrosis factor-alpha play a protective role against obesity and alter adipose tissue macrophage status.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	19477937
Pubmed	Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	15841213
Pubmed	Soluble TNF receptors are produced at sites of inflammation and are inversely associated with self-reported symptoms (WOMAC) in knee osteoarthritis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	24748490
Pubmed	Globular CTRP9 inhibits oxLDL-induced inflammatory response in RAW 264.7 macrophages via AMPK activation.	C1QTNF9B C1QTNF9	2.66e-05	2	180	2	27188183
Pubmed	Regulation of infection with Histoplasma capsulatum by TNFR1 and -2.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	10946295
Pubmed	Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	37612373
Pubmed	The role of TNF in hepatic histopathological manifestations and hepatic CD8+ T cell alloresponses in murine MHC class I disparate GVHD.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	16081594
Pubmed	Quantitative flow cytometric analysis of expression of tumor necrosis factor receptor types I and II on mononuclear cells.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	23316846
Pubmed	The beta1 and beta3 integrins promote T cell receptor-mediated cytotoxic T lymphocyte activation.	ITGB1 ITGB3	2.66e-05	2	180	2	12690105
Pubmed	Progesterone modulates TNF receptors expression by Jurkat cells cultured with plasma from pregnant women with preeclampsia.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	38382266
Pubmed	Exacerbated febrile responses to LPS, but not turpentine, in TNF double receptor-knockout mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	9124479
Pubmed	Tumor necrosis factor receptor p55 and p75 deficiency protects mice from developing experimental autoimmune myasthenia gravis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	11777546
Pubmed	Upregulation of the p75 but not the p55 TNF-alpha receptor mRNA after silica and bleomycin exposure and protection from lung injury in double receptor knockout mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	10101016
Pubmed	No association of polymorphisms in the tumor necrosis factor receptor I and receptor II genes with disease severity in rheumatoid arthritis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	12858434
Pubmed	Circulating tumour necrosis factor receptors 1 and 2 predict contrast-induced nephropathy and progressive renal dysfunction: a prospective cohort study.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	25783484
Pubmed	Urothelial lesion formation is mediated by TNFR1 during neurogenic cystitis.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	16622179
Pubmed	Hypersensitivity of Vagal Pulmonary Afferents Induced by Tumor Necrosis Factor Alpha in Mice.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	28659824
Pubmed	The role of tumor necrosis factor-alpha in liver toxicity, inflammation, and fibrosis induced by carbon tetrachloride.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	11740910
Pubmed	Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer.	ITGB1 ITGB3	2.66e-05	2	180	2	31618629
Pubmed	PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity.	AIRE PRKDC	2.66e-05	2	180	2	25842288
Pubmed	Differential oligodendroglial expression of the tumor necrosis factor receptors in vivo and in vitro.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	7595529
Pubmed	Tumor necrosis factor modulates apoptosis of monocytes in areas of developmentally regulated bone remodeling.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	12054175
Pubmed	Tumor necrosis factor (TNF) receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	9485205
Pubmed	Co-Expression Profile of TNF Membrane-Bound Receptors Type 1 and 2 in Rheumatoid Arthritis on Immunocompetent Cells Subsets.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	31906244
Pubmed	DNA-PKcs interacts with Aire and regulates the expression of toll-like receptors in RAW264.7 cells.	AIRE PRKDC	2.66e-05	2	180	2	22239103
Pubmed	Effect of aerobic training on plasma cytokines and soluble receptors in elderly women with knee osteoarthritis, in response to acute exercise.	TNFRSF1A TNFRSF1B	2.66e-05	2	180	2	22215119
Interaction	ZNF563 interactions	LRP1B UBE2O SHCBP1 HERC1	2.52e-06	12	174	4	int:ZNF563
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	IL13RA1 CD244 CCR9 TNFRSF10B ITGB1 ITGB3 IGF2R PLXNC1 TNFRSF1A TNFRSF1B EPCAM	1.22e-04	394	129	11	471
GeneFamily	Adhesion G protein-coupled receptors, subfamily L	ADGRL1 ADGRL2	3.00e-04	4	129	2	918
GeneFamily	Latent transforming growth factor beta binding proteins	LTBP2 LTBP3	3.00e-04	4	129	2	628
GeneFamily	Ubiquitin specific peptidases	USP9Y USP20 USP12 USP33	6.82e-04	56	129	4	366
GeneFamily	ADAMTS like	THSD4 ADAMTSL1	1.04e-03	7	129	2	947
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF10B TNFRSF1A TNFRSF1B	1.13e-03	29	129	3	782
GeneFamily	CD molecules\|Integrin beta subunits	ITGB1 ITGB3	1.76e-03	9	129	2	1159
GeneFamily	Ras association domain family	RASSF7 RASSF8	2.19e-03	10	129	2	1198
GeneFamily	UPF1 like RNA helicases	SETX HELZ2	2.66e-03	11	129	2	1169
GeneFamily	ATAC complex	YEATS2 KAT2B	3.74e-03	13	129	2	1058
Coexpression	NABA_MATRISOME	THSD4 ADAMTSL1 SFRP4 COL6A6 INHBA C1QTNF9B SEMA5A ADAM29 INTS14 EFEMP1 MEGF9 ADAMTS7 PLXNC1 SPOCK3 C1QTNF9 LTBP2 LTBP3 BMPER ADAMTS14 MUC5AC MUC6	4.88e-06	1008	177	21	MM17056
Coexpression	NABA_MATRISOME	THSD4 ADAMTSL1 SFRP4 COL6A6 INHBA C1QTNF9B SEMA5A ADAM29 INTS14 EFEMP1 MEGF9 ADAMTS7 PLXNC1 SPOCK3 C1QTNF9 LTBP2 LTBP3 BMPER ADAMTS14 MUC5AC MUC6	6.40e-06	1026	177	21	M5889
Coexpression	BUSSLINGER_GASTRIC_PREZYMOGENIC_CELLS	THSD4 HMGCS2 PIGR MUC6 IL33	5.37e-05	60	177	5	M40007
Coexpression	DESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS	THSD4 ERBB4 FAHD2B INHBA TFPI2 SLITRK4 RASSF7 POF1B EFEMP1 RASSF8	5.67e-05	313	177	10	M40228
Coexpression	GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_UP	IL13RA1 ALS2 USP20 PPP1R3C IFNGR2 IGF2R ZNF592 USP33	5.87e-05	196	177	8	M7562
Coexpression	GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP	IL13RA1 CCR9 ARFGEF2 CLDN3 HMGCS2 PPP1R3C IFNGR2 TNFRSF1B	6.31e-05	198	177	8	M8370
Coexpression	GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN	PAG1 RCBTB2 WDR76 ITGB3 CDC45 SHCBP1 SYNE2 LGR6	6.53e-05	199	177	8	M9170
Coexpression	GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN	RALGDS CD244 ADGRG1 ITGB1 KAT2B MICB SYNE2 TNFRSF1B	6.77e-05	200	177	8	M4659
Coexpression	GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP	CCR9 ALS2 PPP1R3G TG LSM12 TNFRSF1B ADGRL2 EPCAM	6.77e-05	200	177	8	M8087
Coexpression	GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP	HEATR5A STIL PARP14 ITGB3 ZMIZ2 PRKDC TNFRSF1B PHLPP2	6.77e-05	200	177	8	M6044
ToppCell	Calu_3\|World / Cell line, Condition and Strain	INHBA ADGRG1 CLDN3 PARP14 RASSF7 SYNE2 HELZ2 ALDH1A3 EPCAM MUC5AC	9.52e-09	200	180	10	a549aa08aeefe905653266dae3936094ff55f8e4
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO4 ADGRB3 ITGA10 ADCY5 LTBP2 LTBP3 LGR6 BMPER CDH13	4.61e-08	177	180	9	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 ERBB4 SFRP4 THSD7A SLC10A4 SEMA5A EFEMP1 SPOCK3 CDH13	5.59e-08	181	180	9	7846c7b33d1b89364c5a704edaa86520db731c89
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB4 ADAMTSL1 RGL3 ZMAT4 CLDN3 CLDN9 EFEMP1 EPCAM MUC5AC	7.74e-08	188	180	9	3cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ADAMTSL1 THSD7A INHBA ITGA10 TNFRSF10B PARP14 SYNE2 CGNL1 BMPER	9.68e-08	193	180	9	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TFPI2 CLDN3 PIGR CCDC78 MS4A8 ALDH1A3 ADGRF1 EPCAM MUC5AC	1.10e-07	196	180	9	3e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TFPI2 CLDN3 PIGR CCDC78 MS4A8 ALDH1A3 ADGRF1 EPCAM MUC5AC	1.10e-07	196	180	9	1efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCell	Severe_COVID-19-Epithelial-transitional_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TFPI2 CLDN3 PIGR CCDC78 MS4A8 ALDH1A3 ADGRF1 EPCAM MUC5AC	1.15e-07	197	180	9	5ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TFPI2 CLDN3 PIGR CCDC78 MS4A8 ALDH1A3 ADGRF1 EPCAM MUC5AC	1.15e-07	197	180	9	08b371309cd790b171ed76cabc7d910e71cd2835
ToppCell	BAL-Severe-Epithelial-Epithelial-transitional_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TFPI2 CLDN3 PIGR CCDC78 MS4A8 ALDH1A3 ADGRF1 EPCAM MUC5AC	1.15e-07	197	180	9	9f49feee38647bbf964974aac96fa75602186b5c
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 SFRP4 INHBA ITGA10 GRIK3 ITGB3 PTPN5 LTBP3 ADAMTS14	1.26e-07	199	180	9	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERBB4 SLITRK4 SEMA5A LRP1B KAT2B ALDH1A3 KIF13A HYDIN CDH13	1.26e-07	199	180	9	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BCL2L15 CLDN3 RASSF7 POF1B PIGR MS4A8 ADGRF1 EPCAM MUC5AC	1.26e-07	199	180	9	e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 ERBB4 SFRP4 THSD7A SLC10A4 SEMA5A EFEMP1 SPOCK3 CDH13	1.31e-07	200	180	9	501a3b93624df463458a35d3e6648d4ccc941724
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 ERBB4 SFRP4 THSD7A SLC10A4 SEMA5A EFEMP1 SPOCK3 CDH13	1.31e-07	200	180	9	d1f36a8232411933b1494168ec912fd0e5246428
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLITRK4 AIRE SEMA5A PKDREJ LRP1B FSIP2 ALDH1A3 KIF13A	2.34e-07	155	180	8	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO4 ADGRB3 ADCY5 LTBP2 LTBP3 LGR6 BMPER CDH13	3.60e-07	164	180	8	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CABP7 RGL3 ADGRG1 CLDN3 MS4A8 EPCAM MUC5AC MUC6	7.93e-07	182	180	8	dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 ERBB4 THSD7A SLC10A4 EFEMP1 SPOCK3 LGR6 CDH13	8.97e-07	185	180	8	0b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL13RA1 SLC7A6 ITGB1 EFEMP1 TNFAIP3 LGR6 ADAMTS14 IL33	9.73e-07	187	180	8	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	P07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THSD4 IL13RA1 COL6A6 INHBA ITGA10 SEMA5A ADCY5 CDH13	1.01e-06	188	180	8	6ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 THSD7A INHBA ITGA10 POF1B CGNL1 BMPER CDH13	1.05e-06	189	180	8	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	droplet-Tongue-nan-3m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT83 GRIK3 RYR1 SYNE2 PRR9 KIF13A KRT36 CDH13	1.10e-06	190	180	8	251e3a33041023bfc4b547c7eb68cfb8f421636f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ANO4 THSD4 INHBA ITGA10 LRP1B LTBP2 LGR6 CDH13	1.10e-06	190	180	8	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PAG1 RTTN SEMA5A STIL WDR76 CDC45 SHCBP1 ASPM	1.10e-06	190	180	8	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB4 ADAMTSL1 RGL3 ADGRG1 CLDN3 RASSF7 CLDN9 EPCAM	1.14e-06	191	180	8	72dbd2e0fabfca8d6f604df35277d3574739a0b3
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB4 RGL3 ADGRG1 ZMAT4 CLDN3 CLDN9 EPCAM MUC5AC	1.14e-06	191	180	8	05731ece7867659c662f952812805f947032fe10
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	TNFRSF10B STIL WDR76 PARP14 IFNGR2 ATP2C1 MICB SHCBP1	1.19e-06	192	180	8	4e689bca7a242f8482e25f273656e2caba8821c0
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ERBB4 ADAMTSL1 RGL3 ZMAT4 CLDN3 CGNL1 EPCAM MUC5AC	1.19e-06	192	180	8	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB4 RGL3 ADGRG1 ZMAT4 CLDN3 MS4A8 EPCAM MUC5AC	1.23e-06	193	180	8	aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCell	Bronchial_Biopsy-Epithelial-Basal_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	THSD4 SEMA5A RPS27 EFEMP1 SPOCK3 LGR6 IL33 CDH13	1.44e-06	197	180	8	a4855c5aebea4f0fed4eb035844572e82e5bac46
ToppCell	Bronchial_Brush-Epithelial\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	CLDN3 PIGR SYNE2 MS4A8 ADGRF1 EPCAM MUC5AC HYDIN	1.44e-06	197	180	8	272c7f4e582ef57564450540242b0db766b78328
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	CLDN3 EFEMP1 PIGR CCDC78 MS4A8 ADGRF1 EPCAM HYDIN	1.44e-06	197	180	8	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BCL2L15 CLDN3 RASSF7 PIGR MS4A8 ADGRF1 EPCAM MUC5AC	1.55e-06	199	180	8	7223f853335492ca617dbec3e4b6872a8a463a45
ToppCell	Caecum-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	HMGCS2 STIL CDC45 ZNF660 SHCBP1 ASPM MS4A8 EPCAM	1.55e-06	199	180	8	64d1e495307a91bc012130613126d86e0cf170b0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 TFPI2 CLDN3 ITGB1 RASSF7 SYNE2 ADGRF1 EPCAM	1.55e-06	199	180	8	2e7f517c0444b4f29ff11c26ab32e9cc0f7e99ef
ToppCell	(1)_T_cell-(18)_cycling_gd_T\|(1)_T_cell / shred on Cell_type and subtype	ZMAT4 STIL CDC45 ZNF660 SPOCK3 SHCBP1 ASPM ADAMTS14	1.55e-06	199	180	8	9369d0e4efe809e3e8757294ebebba5a47b30528
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THSD4 ERBB4 TBC1D30 HMGCS2 POF1B PIGR CGNL1 PNPLA7	1.61e-06	200	180	8	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CBLN1-L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 ERBB4 SFRP4 THSD7A SLC10A4 SEMA5A EFEMP1 CDH13	1.61e-06	200	180	8	2086024ce808b8796ed508a229b098eb02f8828a
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CBLN1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ANO4 ERBB4 SFRP4 THSD7A SLC10A4 SEMA5A EFEMP1 CDH13	1.61e-06	200	180	8	35951db6a4f442ac9e13f1b8cc5b4a33481f92c8
ToppCell	Kidney\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	ERBB4 RGL3 CLDN3 PIGR CGNL1 ADGRF1 EPCAM GP2	1.61e-06	200	180	8	1f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 ADGRG1 CLDN3 ITGB1 RASSF7 EFEMP1 ADGRF1 EPCAM	1.61e-06	200	180	8	d9dab2aed11e45c60d11ff0c5af1f2fbb9cb45d8
ToppCell	Bronchus_Control_(B.)-Epithelial-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CLDN3 PIGR SYNE2 CCDC78 ALDH1A3 ADGRF1 EPCAM MUC5AC	1.61e-06	200	180	8	f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 ADGRG1 CLDN3 ITGB1 RASSF7 EFEMP1 ADGRF1 EPCAM	1.61e-06	200	180	8	33b7af6c50e65dc1bdf429572574ed072f8bc29f
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ANO4 THSD4 SFRP4 ADCY5 EEF2 LTBP3 LGR6 RASSF8	1.61e-06	200	180	8	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERBB4 USP9Y LRP1B SPOCK3 LGR6 KLKB1 HYDIN	4.41e-06	162	180	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	PND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADGRG1 ZMAT4 RASSF7 C1QTNF9 PC EPCAM IL33	5.18e-06	166	180	7	575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAM29 TNFRSF10B RHOH SYNE2 TNFAIP3 LGR6 PNPLA7	5.18e-06	166	180	7	000faacc79b0bd279ddce4e692d801e7e2063ab6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADGRG1 SYNJ1 SYNE2 ASPM SHOC1 LGR6 ZNF541	5.39e-06	167	180	7	abc4ba308ca3be41b0da604f5d82579fd58dff7b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HMGCS2 SHCBP1 SHOC1 ADGRF1 EPCAM MUC6 KLB	5.39e-06	167	180	7	166b7b4ca0663cde6d88219ee0bcc1988d03dab8
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor-MUC5AC+ASCL1+_intermediate_\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ADGRG1 CLDN3 CLDN9 EPCAM MUC5AC MUC6 KLB	6.06e-06	170	180	7	d6e244725b21592c6056b9c443aac090f1eae836
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	ERBB4 RGL3 CLDN3 PIGR MS4A8 EPCAM MUC5AC	6.30e-06	171	180	7	1af575809b3334bfaa019ff26c56e6cb03c82ee8
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	FSIP2 EFEMP1 C1QTNF9 SHOC1 ALDH1A3 MUC5AC MUC6	6.54e-06	172	180	7	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ERBB4 ADGRG1 TNFRSF10B PARP14 MYLIP C1QTNF9 CDH13	6.54e-06	172	180	7	c84cab89c97d647b8a256fd08e33d9102810febd
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SEMA5A STIL WDR76 CDC45 SHCBP1 ASPM PHLPP2	6.79e-06	173	180	7	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	facs-GAT-Fat-24m-Epithelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CLDN3 HMGCS2 RASSF7 PIGR MS4A8 EPCAM	6.79e-06	173	180	7	98e464d9e6d6b69421e9e4041b638b6825247f60
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	SEMA5A STIL WDR76 CDC45 SHCBP1 ASPM PHLPP2	6.79e-06	173	180	7	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	facs-GAT-Fat-24m-Epithelial-epithelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CLDN3 HMGCS2 RASSF7 PIGR MS4A8 EPCAM	6.79e-06	173	180	7	3e6f0a08eddfd61871f7a85acccf6d539af6ebda
ToppCell	facs-GAT-Fat-24m-Epithelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OBSCN CLDN3 HMGCS2 RASSF7 PIGR MS4A8 EPCAM	6.79e-06	173	180	7	815ba48a9222ea09ba8005e2d2f7c5addf118ad1
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGL3 ADAM29 CLDN3 HMGCS2 MSMP MS4A8 EPCAM	7.89e-06	177	180	7	5bccc7a74019eae8afd977a9c9134d884857ac27
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PAG1 COL6A6 OBSCN SEMA5A ADCY5 LTBP2 BMPER	8.18e-06	178	180	7	185b44700f06ec58b3c09c80520502166c965fd6
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TFPI2 CLDN3 PKDREJ PIGR ALDH1A3 ADGRF1 MUC5AC	8.18e-06	178	180	7	49a2271718637522f74334068d252963ee13b1ce
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TFPI2 CLDN3 PKDREJ PIGR ALDH1A3 ADGRF1 MUC5AC	8.18e-06	178	180	7	9a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TFPI2 CLDN3 PKDREJ PIGR ALDH1A3 ADGRF1 MUC5AC	8.18e-06	178	180	7	b413a634283550fa224db7d0d05956e3f64694a1
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	TFPI2 CLDN3 PKDREJ PIGR ALDH1A3 ADGRF1 MUC5AC	8.18e-06	178	180	7	19b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD244 KRT83 CCR9 RHOH MICB SCART1 KLB	8.80e-06	180	180	7	ca7c316027e31559103b2cab1a2c0de993e42e95
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Hematopoietic-T_cells\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD244 KRT83 CCR9 RHOH MICB SCART1 KLB	8.80e-06	180	180	7	eb26ba86fba26899e54c448afc25382ddc853013
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLDN3 PIGR SPOCK3 NAXD CGNL1 PC GP2	9.13e-06	181	180	7	092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RGL3 SEMA5A HEATR5A RASSF7 EFEMP1 CGNL1 CDH13	9.13e-06	181	180	7	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANO4 THSD4 ADGRB3 ITGA10 ADCY5 LTBP2 LGR6	9.13e-06	181	180	7	25915e2500430a902db37d79a749ce2990b69810
ToppCell	3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD7A ITGA10 SPART PTPN5 SCART1 ADGRL2 IL33	9.46e-06	182	180	7	d996ceb77c83591df4cef144ca72862f31d9777f
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 IL13RA1 INHBA HMGCS2 IFNGR2 SYCP2 CDH13	9.80e-06	183	180	7	b4f29dd3994009bb5eb769d36d95886664e7f87d
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TFPI2 SYCP2 ZNF592 BMPER ALDH1A3 ADGRL2 HYDIN	1.09e-05	186	180	7	f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	THSD4 ERBB4 OBSCN SEMA5A ADCY5 ADGRL2 CDH13	1.13e-05	187	180	7	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A SLC10A4 C1QTNF9B EFEMP1 SPOCK3 RASSF8	1.13e-05	187	180	7	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ERBB4 RGL3 LRP1B LTBP2 CGNL1 GP2	1.17e-05	188	180	7	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SFRP4 INHBA ARFGEF2 SLC7A6 IGF2R LTBP2 ALDH1A3	1.17e-05	188	180	7	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 ERBB4 ZMAT4 GRIK3 SPOCK3 ASPM RASSF8	1.17e-05	188	180	7	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	PAG1 PARP14 ATP2C1 IGF2R SYNE2 TNFAIP3 HERC1	1.17e-05	188	180	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Severe_COVID-19-Epithelial-undefined_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	THSD7A TFPI2 CLDN3 PIGR ALDH1A3 ADGRF1 MUC5AC	1.21e-05	189	180	7	8cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO4 ERBB4 ADGRG1 LRP1B CGNL1 EPCAM GP2	1.25e-05	190	180	7	68ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-filiform\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRIK3 RYR1 SYNE2 PRR9 KIF13A KRT36 CDH13	1.25e-05	190	180	7	8a53f4d3c9aca45b5826f53f7dcdfb8bc8280acb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ERBB4 RGL3 LRP1B LTBP2 CGNL1 GP2	1.25e-05	190	180	7	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO4 ERBB4 ADGRG1 LRP1B CGNL1 EPCAM GP2	1.25e-05	190	180	7	010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 THSD7A SLC10A4 ADGRG1 SEMA5A SPOCK3 CDH13	1.29e-05	191	180	7	06760c3bb40e4f66879a5f5e09c9abfce4ebbba3
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Cycling_Myeloid-Mac\|GI_small-bowel / Manually curated celltypes from each tissue	SIGLEC12 IL13RA1 STIL CDC45 KLK4 SHCBP1 ASPM	1.29e-05	191	180	7	c3944332c5226b0113f8aa9ac07837b755606c6c
ToppCell	Healthy_Control-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CLDN3 EFEMP1 PIGR CCDC78 MS4A8 ADGRF1 HYDIN	1.29e-05	191	180	7	fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD4 HMGCS2 RASSF7 PTPN5 PC EPCAM IL33	1.29e-05	191	180	7	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	Healthy_Control-Epithelial-Epithelial-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CLDN3 EFEMP1 PIGR CCDC78 MS4A8 ADGRF1 HYDIN	1.29e-05	191	180	7	28caedb2e448e0c7f494100d714fa7cdcf150691
ToppCell	Healthy_Control-Epithelial-Epithelial\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CLDN3 EFEMP1 PIGR CCDC78 MS4A8 ADGRF1 HYDIN	1.29e-05	191	180	7	15b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB4 ADAMTSL1 RGL3 CLDN3 CLDN9 EFEMP1 EPCAM	1.29e-05	191	180	7	63aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell	facs-GAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A COL6A6 HMGCS2 EFEMP1 BMPER ALDH1A3 PDLIM2	1.29e-05	191	180	7	1f5d1e8c313a8dc83c06d2ee45f369b0ec507fbf
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	ADAMTSL1 THSD7A INHBA ITGA10 POF1B CGNL1 BMPER	1.34e-05	192	180	7	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	P15-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THSD4 INHBA SEMA5A HMGCS2 ADCY5 LTBP2 CDH13	1.34e-05	192	180	7	a476895b7b252c388d6346eacbc72f0115b1443e
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 COL6A6 INHBA ITGA10 SEMA5A ADCY5 CDH13	1.34e-05	192	180	7	26d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCell	COVID-19_Moderate-CD4+_T_activated\|COVID-19_Moderate / disease group, cell group and cell class	PAG1 RPS27 RHOH MYLIP HELZ2 TNFAIP3 HERC5	1.34e-05	192	180	7	7a81652406332afd03a9b3b529e9b5e6c0b54c28
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ERBB4 ADAMTSL1 RGL3 CLDN3 CLDN9 EFEMP1 EPCAM	1.34e-05	192	180	7	b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 COL6A6 INHBA ITGA10 SEMA5A ITGB1 CDH13	1.38e-05	193	180	7	88916d9a7d831eb52848599917c04238f8f9812b
ToppCell	PCW_05-06-Epithelial-Epithelial_airway\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB4 ADAMTSL1 RGL3 CLDN3 RASSF7 CLDN9 EPCAM	1.38e-05	193	180	7	af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB4 ADAMTSL1 RGL3 CLDN3 CLDN9 EFEMP1 EPCAM	1.38e-05	193	180	7	b25cdca3a1e381784ae48ca73c51cbb6ac62b811
Drug	Amiprilose hydrochloride [60414-06-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A	SFRP4 INHBA AIRE ADGRL1 SEMA5A ZMAT4 ITGB3 USP20 TG TNFAIP3 HERC5	3.65e-07	196	175	11	4119_UP
Drug	Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A	TBC1D30 ITGA10 ADGRG1 ADGRL1 RCBTB2 DDX51 ZNF592 PLXNC1 ZMIZ2 LTBP2 TNFAIP3	4.04e-07	198	175	11	2848_UP
Disease	glomerulonephritis (is_marker_for)	ITGB3 TNFRSF1A TNFRSF1B KLKB1	4.42e-06	19	176	4	DOID:2921 (is_marker_for)
Disease	cryptogenic organizing pneumonia (is_marker_for)	TNFRSF1A TNFRSF1B	3.54e-05	2	176	2	DOID:0050157 (is_marker_for)
Disease	Mitral valve prolapse, response to surgery	ZNF592 LTBP2 LTBP3	4.41e-05	12	176	3	EFO_0009951, HP_0001634
Disease	colon carcinoma (is_marker_for)	IGF2R TNFRSF1A TNFRSF1B	5.71e-05	13	176	3	DOID:1520 (is_marker_for)
Disease	skin disease (implicated_via_orthology)	C1QTNF9B C1QTNF9	1.06e-04	3	176	2	DOID:37 (implicated_via_orthology)
Disease	Internal Carotid Artery Thrombosis	ITGB3 KLKB1	2.11e-04	4	176	2	C0750990
Disease	Common Carotid Artery Thrombosis	ITGB3 KLKB1	2.11e-04	4	176	2	C0750988
Disease	External Carotid Artery Thrombosis	ITGB3 KLKB1	2.11e-04	4	176	2	C0750989
Disease	Crohn's disease (biomarker_via_orthology)	TNFRSF1A TNFRSF1B	2.11e-04	4	176	2	DOID:8778 (biomarker_via_orthology)
Disease	Carotid Artery Thrombosis	ITGB3 KLKB1	2.11e-04	4	176	2	C0007274
Disease	Primary microcephaly	RTTN STIL ASPM	2.96e-04	22	176	3	C0431350
Disease	Pneumonia	CCR9 TNFRSF1A TNFRSF1B IL33	3.07e-04	54	176	4	C0032285
Disease	Lobar Pneumonia	CCR9 TNFRSF1A TNFRSF1B IL33	3.07e-04	54	176	4	C0032300
Disease	Pneumonitis	CCR9 TNFRSF1A TNFRSF1B IL33	3.07e-04	54	176	4	C3714636
Disease	Experimental Lung Inflammation	CCR9 TNFRSF1A TNFRSF1B IL33	3.07e-04	54	176	4	C0887898
Disease	mucinous adenocarcinoma (is_marker_for)	MUC5AC MUC6	3.50e-04	5	176	2	DOID:3030 (is_marker_for)
Disease	polybrominated biphenyl measurement, gestational serum measurement, polybrominated diphenyl ether measurement	ADAMTSL1 MICB	3.50e-04	5	176	2	EFO_0007961, EFO_0007962, EFO_0007964
Disease	interleukin-13 receptor subunit alpha-1 measurement	IL13RA1 KLKB1	3.50e-04	5	176	2	EFO_0020493
Disease	severe acute respiratory syndrome, COVID-19	THSD4 THSD7A ADGRG1 ZMAT4 LRP1B TG USP12 LTBP2 LTBP3 CDH13	3.74e-04	447	176	10	EFO_0000694, MONDO_0100096
Disease	hepatocellular carcinoma (is_marker_for)	HMGCS2 LRP1B KAT2B IGF2R EFEMP1 ASPM TNFAIP3 EPCAM	4.73e-04	301	176	8	DOID:684 (is_marker_for)
Disease	periventricular nodular heterotopia (is_implicated_in)	ARFGEF2 ERMARD	5.22e-04	6	176	2	DOID:0050454 (is_implicated_in)
Disease	acne (is_implicated_in)	TNFRSF1A TNFRSF1B	5.22e-04	6	176	2	DOID:6543 (is_implicated_in)
Disease	serum dimethylarginine measurement	THSD4 ERBB4 LRP1B CDH13	5.54e-04	63	176	4	EFO_0005418
Disease	cholangiocarcinoma (is_marker_for)	TNFAIP3 RASSF8 MUC5AC MUC6	5.88e-04	64	176	4	DOID:4947 (is_marker_for)
Disease	Hereditary Autoinflammatory Diseases	TNFAIP3 TNFRSF1A	7.28e-04	7	176	2	C0751422
Disease	acquired immunodeficiency syndrome (is_marker_for)	TNFRSF1A TNFRSF1B	7.28e-04	7	176	2	DOID:635 (is_marker_for)
Disease	arabinose measurement	ERBB4 CDH13	7.28e-04	7	176	2	EFO_0021030
Disease	cholesteryl ester 16:2 measurement	LTBP2 LTBP3	7.28e-04	7	176	2	EFO_0021435
Disease	Periventricular Nodular Heterotopia	ARFGEF2 ERMARD	7.28e-04	7	176	2	C1868720
Disease	Manic Disorder	THSD7A PACS1 ZNF592 PC	8.71e-04	71	176	4	C0024713
Disease	Hantavirus hemorrhagic fever with renal syndrome (is_marker_for)	ITGB3 IL33	9.67e-04	8	176	2	DOID:11266 (is_marker_for)
Disease	thrombin generation potential measurement, thrombomodulin measurement	RALGDS KLKB1	9.67e-04	8	176	2	EFO_0005538, EFO_0007774
Disease	visual epilepsy (implicated_via_orthology)	ERBB4 TNFRSF1A TNFRSF1B	1.09e-03	34	176	3	DOID:11832 (implicated_via_orthology)
Disease	Tinnitus	ADAM29 EFEMP1 RASSF8 TNFRSF1A CDH13	1.12e-03	130	176	5	HP_0000360
Disease	Manic	THSD7A PACS1 ZNF592 PC	1.24e-03	78	176	4	C0338831
Disease	Mitral valve prolapse	ZNF592 LTBP2 LTBP3	1.29e-03	36	176	3	HP_0001634
Disease	Depression, Bipolar	THSD7A PACS1 ZNF592 PC	1.30e-03	79	176	4	C0005587
Disease	body weight	IL13RA1 ERBB4 RTTN ADGRB3 C1QTNF9B LRP1B ADCY5 EFEMP1 SPOCK3 SCMH1 ZMIZ2 LTBP2 LTBP3 ATXN10 ADAMTS14 CDH13 GP2	1.50e-03	1261	176	17	EFO_0004338
Disease	Depressive disorder	GRIK3 ADCY5 TG PER3 TNFRSF1A TNFRSF1B CDH13	1.81e-03	289	176	7	C0011581
Disease	polymyositis (is_marker_for)	TNFRSF1A TNFRSF1B	1.88e-03	11	176	2	DOID:0080745 (is_marker_for)
Disease	Autoimmune Diseases	TG TNFAIP3 TNFRSF1A	2.02e-03	42	176	3	C0004364
Disease	age at onset, Myopia	ADAMTSL1 ZMAT4 RCBTB1 HYDIN CDH13	2.10e-03	150	176	5	EFO_0004847, HP_0000545
Disease	Diabetes Mellitus, Non-Insulin-Dependent	IL13RA1 SFRP4 ADCY5 TNFRSF1A TNFRSF1B GP2	2.17e-03	221	176	6	C0011860
Disease	stenosing tenosynovitis	LTBP2 LTBP3	2.24e-03	12	176	2	EFO_0010822
Disease	glaucoma	THSD7A LRP1B EFEMP1 LTBP2 LTBP3	2.36e-03	154	176	5	MONDO_0005041
Disease	Autosomal Dominant Myotubular Myopathy	RYR1 CCDC78	2.64e-03	13	176	2	C3661489
Disease	Centronuclear myopathy	RYR1 CCDC78	2.64e-03	13	176	2	C0175709
Disease	X-linked centronuclear myopathy	RYR1 CCDC78	2.64e-03	13	176	2	C0410203
Disease	Myopathy, Centronuclear, 1	RYR1 CCDC78	2.64e-03	13	176	2	C4551952
Disease	rostral anterior cingulate cortex volume measurement	CGNL1 FBXL2	2.64e-03	13	176	2	EFO_0010327
Disease	Congenital Structural Myopathy	RYR1 CCDC78	2.64e-03	13	176	2	C0752282
Disease	pneumonia	HELZ2 TNFRSF1A MUC5AC	2.79e-03	47	176	3	EFO_0003106
Disease	Endometrioma	ANO4 ITGB1 PLXNC1 MYLIP HERC5	2.86e-03	161	176	5	C0269102
Disease	Endometriosis	ANO4 ITGB1 PLXNC1 MYLIP HERC5	2.86e-03	161	176	5	C0014175
Disease	gastric ulcer (implicated_via_orthology)	MUC5AC MUC6	3.07e-03	14	176	2	DOID:10808 (implicated_via_orthology)
Disease	Myopathy, Centronuclear, Autosomal Dominant	RYR1 CCDC78	3.07e-03	14	176	2	C1834558
Disease	Tubular Aggregate Myopathy	RYR1 CCDC78	3.07e-03	14	176	2	C0410207
Disease	precuneus cortex volume measurement	PIGR CDH13	3.07e-03	14	176	2	EFO_0010326
Disease	extrinsic allergic alveolitis (is_marker_for)	TNFRSF1A TNFRSF1B	3.07e-03	14	176	2	DOID:841 (is_marker_for)
Disease	Pancreatic Neoplasm	TFPI2 TNFRSF10B EFEMP1 EPCAM	3.07e-03	100	176	4	C0030297
Disease	multiple sclerosis	ADAMTSL1 TG IFNGR2 RHOH IGF2R PLXNC1 RCBTB1 TNFAIP3 TNFRSF1A TOP3A	3.13e-03	594	176	10	MONDO_0005301
Disease	complement factor H-related protein 4 measurement	ASPM ADGRL2 CDH13	3.14e-03	49	176	3	EFO_0600091
Disease	Malignant neoplasm of pancreas	TFPI2 TNFRSF10B EFEMP1 EPCAM	3.30e-03	102	176	4	C0346647
Disease	3-hydroxyanthranilic acid measurement	TG ADGRF1	3.53e-03	15	176	2	EFO_0010447
Disease	Autosomal recessive primary microcephaly	STIL ASPM	3.53e-03	15	176	2	cv:C3711387
Disease	Graves' disease (is_marker_for)	ITGB3 TG	3.53e-03	15	176	2	DOID:12361 (is_marker_for)
Disease	Autosomal Recessive Centronuclear Myopathy	RYR1 CCDC78	3.53e-03	15	176	2	C3645536
Disease	autoimmune disease	ITGB3 TG RHOH PLXNC1 TNFAIP3	3.88e-03	173	176	5	EFO_0005140
Disease	lung small cell carcinoma (is_marker_for)	ITGB1 EEF2	4.02e-03	16	176	2	DOID:5409 (is_marker_for)
Disease	urate measurement, bone density	THSD4 ERBB4 ADGRB3 TG FSIP2 PLXNC1 C1QTNF9 HELZ2 PRKDC CDH13	4.18e-03	619	176	10	EFO_0003923, EFO_0004531
Disease	Mental Depression	GRIK3 ADCY5 PER3 TNFRSF1A TNFRSF1B CDH13	4.31e-03	254	176	6	C0011570
Disease	Astrocytosis	ITGB1 ITGB3	4.54e-03	17	176	2	C3887640
Disease	Amyotrophic lateral sclerosis	SETX ALS2	4.54e-03	17	176	2	cv:C0002736
Disease	Gliosis	ITGB1 ITGB3	4.54e-03	17	176	2	C0017639
Disease	acute kidney failure (is_marker_for)	TNFRSF1A TNFRSF1B	4.54e-03	17	176	2	DOID:3021 (is_marker_for)
Disease	optic cup area measurement	EFEMP1 LTBP2 LTBP3	4.59e-03	56	176	3	EFO_0006940
Disease	conotruncal heart malformations	ADAM29 PLXNC1 SPOCK3 CDH13	4.91e-03	114	176	4	MONDO_0016581
Disease	Drug habituation	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C0013170
Disease	Drug abuse	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C0013146
Disease	Prescription Drug Abuse	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C4316881
Disease	Substance-Related Disorders	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C0236969
Disease	Drug Use Disorders	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C0013222
Disease	Drug Dependence	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C1510472
Disease	Substance Dependence	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C0038580
Disease	Substance Use Disorders	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	ANO4 THSD4 PACS1 CDH13	5.06e-03	115	176	4	C0029231
Disease	lupus nephritis (is_implicated_in)	TNFRSF1B KLKB1	5.08e-03	18	176	2	DOID:0080162 (is_implicated_in)
Disease	Congenital Fiber Type Disproportion	RYR1 CCDC78	5.08e-03	18	176	2	C0546264
Disease	Substance abuse problem	ANO4 THSD4 PACS1 CDH13	5.22e-03	116	176	4	C0740858
Disease	Malignant neoplasm of breast	ERBB4 GFRAL HK3 TFPI2 OBSCN ARFGEF2 GRIK3 PKDREJ EEF2 EFEMP1 PER3 SYNE2 LGR6 ZNF541	5.22e-03	1074	176	14	C0006142
Disease	congenital heart disease	ADAM29 LRP1B CDH13	5.31e-03	59	176	3	EFO_0005207
Disease	prion disease	ATRIP ADAMTS14	5.66e-03	19	176	2	EFO_0004720
Disease	acetone measurement	HMGCS2 SCART1	5.66e-03	19	176	2	EFO_0010989
Disease	hydrocephalus (implicated_via_orthology)	ITGB1 HYDIN	5.66e-03	19	176	2	DOID:10908 (implicated_via_orthology)
Disease	disease progression measurement	ADCY5 RHOH HERC1	5.83e-03	61	176	3	EFO_0008336
Disease	open-angle glaucoma	THSD7A ITGB3 EFEMP1 LTBP2 LTBP3	5.88e-03	191	176	5	EFO_0004190

Protein segments in the cluster

Peptide	Gene	Start	Entry
QTCNKVRCVVPQTTV	BANP	106	Q8N9N5
ISDVQCGRIQCENVT	ADAM29	546	Q9UKF5
TENHCQTLTRTVCAE	ERBB4	201	Q15303
QTLTRTVCAEQCDGR	ERBB4	206	Q15303
CQCTSVGAQNTVICS	EPCAM	46	P16422
IQTRDTNFGTNCICR	BUD31	106	P41223
VRSSFANQGEICLCT	ALDH8A1	276	Q9H2A2
ANQGEICLCTSRIFV	ALDH8A1	281	Q9H2A2
CFASAVECLQQISTT	ALS2	1551	Q96Q42
LVNETQDIVTCQCTH	ADGRF1	551	Q5T601
TEGCLTQELQTTQVC	ADGRB3	226	O60242
TCGQGSQVRTRTCVS	ADGRB3	306	O60242
ETTNIFSNCGCVRAE	ATXN10	346	Q9UBB4
IMSQRCNNRTQCVVV	ADGRL1	91	O94910
CNNRTQCVVVAGSDA	ADGRL1	96	O94910
QTLTRICADAQCVVD	ARFGEF2	501	Q9Y6D5
GQCCTAASRVFVEEQ	ALDH1A3	311	P47895
QQCQGDTVISECLQR	ACAP3	66	Q96P50
VNNTFQTCVEVGVRV	ACOT12	251	Q8WYK0
RCNNRTQCIVVTGSD	ADGRL2	96	O95490
SNVLIFSCTNIVGVC	ADCY5	381	O95622
SQVATTGTAVCINFC	ANO4	546	Q32M45
NITDLRVQVCSCRNS	CDH13	671	P55290
ICQRTTQTVECTQTG	ASPM	1161	Q8IZT6
VSRIVEAGCVCNDAV	ATP2C1	401	P98194
SATCGEGIQQRQVVC	ADAMTS14	981	Q8WXS8
VTCGEGTQRRNVLCT	ADAMTS7	956	Q9UKP4
RCSSCLQATVQEVQP	AIRE	336	O43918
RIACEQCQESGASLV	INHBA	241	P08476
GIQRVVCGVSEQTTC	RASSF7	16	Q02833
VCGVSEQTTCQEVVI	RASSF7	21	Q02833
QRIVCGVTEVTTCQE	RASSF8	11	Q8NHQ8
RVAALHSVCVNQIVC	RCBTB1	226	Q8NDN9
TTVNDEIFVLGTNCC	RCBTB2	61	O95199
LISSVCCVFAQTDEN	ITGB1	11	P05556
FIATSICCQQLRQEG	PTPN5	506	P54829
QCVNVSVVSEEVCSK	KLK4	166	Q9Y5K2
TVCLETGSQNVQLCT	SLC10A4	331	Q96EP9
NVTVTRCEGACISAA	MUC6	2366	Q6W4X9
SFNIITQQVDARCSC	MUC6	2381	Q6W4X9
QSCSRITDEGVVQIC	FBXL2	216	Q9UKC9
TNGSALCTRCIQINT	FLII	1061	Q13045
VGSQVSCRTCQEQRL	LSM12	11	Q3MHD2
SCRTCQEQRLQGEVV	LSM12	16	Q3MHD2
RIFVCNSNGSVCVTL	LRP1B	306	Q9NZR2
TCVKTSQTAVCIEAN	MCMDC2	256	Q4G0Z9
SQTAVCIEANSITFC	MCMDC2	261	Q4G0Z9
QQIIVSLTESCRSCS	KAT2B	126	Q92831
TCVEVIVTNENTSCT	GGNBP2	426	Q9H3C7
TLAAVQCSVSVSCVR	LGR6	661	Q9HBX8
VTVSNRLVSSSCCIV	HSP90AB2P	351	Q58FF8
CSNRSKDVLVVNCTA	HERC1	3806	Q15751
CSVAACNTEAQGVQE	IKBKE	626	Q14164
QVNLIFCDEVSVSAC	FSIP2	5961	Q5CZC0
VTCGVGTQVRIVRCQ	ADAMTSL1	536	Q8N6G6
CSVQEDINSLCLTVV	HMGCS2	96	P54868
TVTQEIDIQACVTCE	PER3	1166	P56645
VCRNISVNVLDCDTI	PLXNC1	1216	O60486
VAVCSCLTSQIRDVG	KLHL8	596	Q9P2G9
EQCQPSCSRSQVRSE	GP2	471	P55259
QQVLVCSQEGSSRRC	NAXD	256	Q8IW45
SSCEGLSCQQTRVLQ	MYLIP	361	Q8WY64
CSVVGSLNVNRCNQT	MEGF9	206	Q9H1U4
VTCSEVSEGNITVTC	MICB	211	Q29980
QTIRVGCNTCTCDSR	MUC5AC	876	P98088
VVQCSREEGLVCRNQ	MUC5AC	2181	P98088
QVVQCSREEGLVCRN	MUC5AC	3286	P98088
QVVQCSREEGLVCRN	MUC5AC	4691	P98088
LCSQDCQVVRGVDSD	MUC5AC	4811	P98088
VRATVAQFNTVTGCV	RGL3	291	Q3MIN7
LEVCQAVSQRAAQLC	HK3	826	P52790
CHSGSSQICEQVIIQ	POF1B	231	Q8WVV4
SICVVQDGRLEVCIQ	PNPLA7	181	Q6ZV29
NERICLQVGSQCSTN	IL13RA1	91	P78552
VCTCSTVEVQAVLSA	PACS1	591	Q6VY07
QVQSRTKIEECVVCS	MIB1	856	Q86YT6
TVDASENVQCCVIFS	HERC5	616	Q9UII4
TLTISQCCLEDVGQV	OBSCN	476	Q5VST9
VGCTRRLVVQQACQA	OBSCN	1401	Q5VST9
SCVCGQERTSATLTV	OBSCN	3871	Q5VST9
SATFRVCGENVTCVE	PARP14	1426	Q460N5
EICTGNINSQDTCRQ	C1QTNF9	11	P0C862
TQQTIASCLCTNLVI	CDC45	426	O75419
VLAACQQQSTVECFA	IL33	81	O95760
VDFATIQCGQCLVET	HYDIN	1706	Q4G0P3
ATQTQIDAVCCRRCV	HEATR5A	341	Q86XA9
RQCQEGVVTESGVRC	BMPER	131	Q8N8U9
DVETCSNQQIRQTCV	CABP7	171	Q86V35
DILGTVLQVQCTCRT	GFRAL	281	Q6UXV0
VLQVQCTCRTITQSE	GFRAL	286	Q6UXV0
CCRVNGEVVQSSNTN	FAHD2B	236	Q6P2I3
TSVCVNVQSCTKERV	CGNL1	231	Q0VF96
QRRQAQAVTAASTCC	DDX51	406	Q8N8A6
TCLESALVGVCNIVQ	INTS14	86	Q96SY0
ISNCAVSTNIDICFQ	CCR9	286	P51686
EICTGNINSQDTCRQ	C1QTNF9B	11	B2RNN3
CETVRRETQTSCFCN	ADGRG1	366	Q9Y653
QRLATQAVVLCSCQG	CCDC78	206	A2IDD5
VLGRNTTQAECCCTQ	LTBP2	1426	Q14767
QVTETDECRLNQNIC	LTBP3	571	Q9NS15
SVLATNVTQQECCCS	LTBP3	931	Q9NS15
GCQLVCCQSSNVSVI	MS4A8	206	Q9BY19
QFNSVANCVITTCLG	RALGDS	436	Q12967
SIGVNCTQITATECD	IFNGR2	81	P38484
QEAVCLTAALCFQVT	ITGA10	671	O75578
CTTRGVSSCQQCLAV	ITGB3	31	P05106
VSSVEECQKRCTNNI	KLKB1	131	P03952
CSQTQENTECTVCLF	KLB	976	Q86Z14
LVVVDCVSGVCVQTE	EEF2	126	P13639
CVSGVCVQTETVLRQ	EEF2	131	P13639
NCDINSIVTQNGEVC	ERMARD	31	Q5T6L9
TGSNCQCNVEVVRAL	ATRIP	676	Q8WXE1
SCTNAVQSICNALEV	GRIK3	116	Q13003
EQRCICVVSHGAQVS	HELZ2	826	Q9BYK8
CVCNGVAVRSNQDLI	RYR1	606	P21817
CQVALSCLVSRDGNV	CD244	151	Q9BZW8
RICEIQAVDCTTISS	KCTD3	521	Q9Y597
NVTETQVCLSIEACT	C18orf63	146	Q68DL7
IVRNICTTAGESNCF	COL6A6	1171	A6NMZ7
CTTAGESNCFVDVVV	COL6A6	1176	A6NMZ7
RLCEGVEAVNVCVSS	KRT83	421	P78385
VSSSEQLQCCQTEII	KRT36	296	O76013
RSCVNGTLVCSTTQL	KIF13A	511	Q9H1H9
VVRSRTCQDINECET	EFEMP1	326	Q12805
CEQATECSVRNGSSI	IGF2R	1646	P11717
CSIADATLIQTCVQE	RTTN	1646	Q86VV8
DISVEICNVCSCVSV	SLITRK4	21	Q8IW52
SCTGAVRCQSQVAEA	HARS2	26	P49590
VRCQSQVAEAVLTSQ	HARS2	31	P49590
FVCLENCSLQERTVT	PPP1R3C	156	Q9UQK1
TFQSCVITKECQVSE	THSD7A	351	Q9UPZ6
QVCLEHTQAAAVCRS	SYNE2	4611	Q8WXH0
VQRCQSGTVRTNCLD	SYNJ1	371	O43426
QTVVLCVGCSTVLCQ	RPS27L	51	Q71UM5
CSALSNRGVQQVFEC	RHOH	151	Q15669
SSVSCQINACVIQRV	PKDREJ	206	Q9NTG1
TNICTACEPIQIVNV	GUCY1B2	401	O75343
QKDCVIVTCVRANSI	SETX	2381	Q7Z333
VIEIQASDSQCQAFC	SHOC1	581	Q5VXU9
NVIENCICANMSVSR	OR56A3	176	Q8NH54
QRVCLERVQCSTASG	PPP1R3G	216	B7ZBB8
TLENCVLQCETTGVT	SHCBP1	456	Q8NEM2
SVVIQQLCSVCVFVV	PIGC	56	Q92535
CRQSVNVESILGNSC	PAG1	236	Q9NWQ8
SVTVQEGLCVSVLCS	SIGLEC12	31	Q96PQ1
CEKCSTSIANQAVRI	PDLIM2	286	Q96JY6
SVVLQQAVQACIDCA	SCMH1	391	Q96GD3
SECEASGVQVRARQC	SEMA5A	906	Q13591
TLQVASRNLCCVDEV	BCL2L15	26	Q5TBC7
VALVGAQCTNCVQDD	CLDN3	96	O15551
LVAITGAQCTTCVED	CLDN9	96	O95484
NACATQAIVSVLLNC	UCHL5	86	Q9Y5K5
EIINCSNCESVGTNA	STIL	1176	Q15468
SQFLVDGVCTVANCV	SPART	491	Q8N0X7
EVTVQRNCCLTLCNF	ZER1	451	Q7Z7L7
CEVRQEAGTCQFSLV	MSMP	91	Q1L6U9
CQACLQDVTRTFNGI	TNFAIP3	521	P21580
IITEDNKVNGVTCCT	PHLPP2	936	Q6ZVD8
AGQANVCDVVTSTVC	SLC26A1	256	Q9H2B4
VQRSGCNEVTTVVDV	SFRP4	206	Q6FHJ7
CSLVIDSRVNICIQQ	SYCP2	156	Q9BX26
QRTTEETEGLTCQVC	ZNF592	731	Q92610
CNECGKTFRQTSQVI	ZNF660	276	Q6AZW8
SQCGTVIDVNIDCAV	UBE2O	161	Q9C0C9
FQGTLTNETRCLTCE	USP12	176	O75317
IASCVNCLTVLAARN	NUP188	611	Q5SRE5
LVQAQEVCLSQCQES	PRR9	46	Q5T870
VRCLGTETRLTQCNV	SCART1	501	Q4G0T1
LSDSVCAVCGQQIFV	RNF121	221	Q9H920
VQRNCDIVTACLQAV	TBC1D30	196	Q9Y2I9
TTRNTVCQCEEGTFR	TNFRSF10B	131	O14763
SVVSQLIRCCNVSST	USP9Y	2231	O00507
CRQSSGENCDVVVNT	PIGR	271	P01833
DICQRGTSLTIQCQV	TRBV29-1	26	A0A5B7
LCTVQSVNCRDIEGR	TNKS2	511	Q9H2K2
LVQCLTCDRVSTTVE	USP20	456	Q9Y2K6
VTCNCGQEAVLLTVR	TOP3A	811	Q13472
CIAQDSQTAVCISHR	SPOCK3	101	Q9BQ16
CRSRSQGCSEQVLTV	PRKDC	3286	P78527
CQPGRNTIQITVTAC	ZMIZ2	516	Q8NF64
AITRGTQQLCFCVLT	SLC7A6	486	Q92536
RETVFVCASCNQTLS	ZFYVE27	396	Q5T4F4
LTGNRVVTTCADCNL	WDR76	506	Q9H967
FTNSEVTCQCLEVVG	XPOT	196	O43592
ETQACTREQNRICTC	TNFRSF1B	106	P20333
GTQVNVTCIVNVCSS	TNFRSF1B	376	P20333
CRLQVSVDDQCEGST	TFPI2	96	P48307
IECGSGTQQREVICV	THSD4	866	Q6ZMP0
NTAVCVCNESVRTVI	ARHGAP21	261	Q5T5U3
VCNNSSVQVGCLTRE	TG	1346	P01266
QVEISSCTVDRDTVC	TNFRSF1A	111	P19438
NIRINGCAIQCRVTT	PC	366	P11498
LLSAQVCCVRGIQVE	TRAV22	11	A0A0B4J277
CKVCSAQLISESQRV	ZMAT4	16	Q9H898
QTVVLCVGCSTVLCQ	RPS27	51	P42677
SVQCLTCDRVSVTLE	USP33	486	Q8TEY7
TCCDVSSNNRLVVTG	TLE6	546	Q9H808
GQQQVCVSQATVGTC	YEATS2	991	Q9ULM3
ETQDRVTELCNVACS	ZNF541	1096	Q9H0D2
TATCRAGSQERVCFQ	KIAA1958	61	Q8N8K9