Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	allyl-alcohol dehydrogenase activity	AKR1B10 AKR1B15 AKR1B1	2.68e-06	4	176	3	GO:0047655
GeneOntologyMolecularFunction	aldose reductase (NADPH) activity	AKR1B10 AKR1B15 AKR1B1	2.28e-04	14	176	3	GO:0004032
GeneOntologyMolecularFunction	retinal dehydrogenase activity	AKR1B10 AKR1B15 AKR1B1	2.28e-04	14	176	3	GO:0001758
GeneOntologyMolecularFunction	all-trans-retinol dehydrogenase (NADP+) activity	AKR1B10 AKR1B15 AKR1B1	2.83e-04	15	176	3	GO:0052650
GeneOntologyBiologicalProcess	clathrin-coated vesicle cargo loading	AP3M1 AP3M2 AP3D1	1.98e-05	7	173	3	GO:0035652
GeneOntologyBiologicalProcess	clathrin-coated vesicle cargo loading, AP-3-mediated	AP3M1 AP3M2 AP3D1	1.98e-05	7	173	3	GO:0035654
GeneOntologyBiologicalProcess	locomotory exploration behavior	LRRK2 LSAMP DLG4 TNR	3.11e-05	22	173	4	GO:0035641
GeneOntologyBiologicalProcess	vesicle transport along microtubule	SYBU AP3M1 AP3M2 KIF5B AP3D1	6.73e-05	51	173	5	GO:0047496
GeneOntologyBiologicalProcess	synaptic vesicle transport	LRRK2 AP3M1 AP3M2 KIF5B AP3D1	8.89e-05	54	173	5	GO:0048489
GeneOntologyBiologicalProcess	anterograde axonal transport	SYBU AP3M1 AP3M2 KIF5B AP3D1	9.71e-05	55	173	5	GO:0008089
GeneOntologyCellularComponent	neuron projection cytoplasm	LRRK2 SYBU AP3M1 CDKL5 AP3M2 DLG4 KIF5B AP3D1	4.62e-06	110	178	8	GO:0120111
GeneOntologyCellularComponent	axon	RELN HTR3A LRRK2 NCAM2 SYBU ATAT1 CBL AP3M1 CDKL5 DOCK7 AP3M2 DLG3 DLG4 LRRC7 TANC1 KIF5B WDFY3 PARD3 CDH1 AP3D1	7.57e-05	891	178	20	GO:0030424
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	LRRK2 SYBU SAXO1 AP3M1 CDKL5 AP3M2 DLG4 KIF5B AKR1B1 AP3D1 HYDIN	9.02e-05	317	178	11	GO:0032838
GeneOntologyCellularComponent	AP-3 adaptor complex	AP3M1 AP3M2 AP3D1	1.63e-04	13	178	3	GO:0030123
GeneOntologyCellularComponent	glutamatergic synapse	PRUNE2 HTR3A RASGRF2 LRRK2 DOCK10 GABBR2 CBLN1 CDKL5 CBLN2 EIF4E AP3M2 DLG3 DLG4 LRRC7 TANC1 CDH1 TNR AP3D1	2.21e-04	817	178	18	GO:0098978
GeneOntologyCellularComponent	RSC-type complex	ARID2 SMARCC2 PHF10	2.56e-04	15	178	3	GO:0016586
GeneOntologyCellularComponent	cytoplasmic region	LRRK2 SYBU SAXO1 AP3M1 CDKL5 AP3M2 DLG4 KIF5B AKR1B1 AP3D1 HYDIN	2.73e-04	360	178	11	GO:0099568
GeneOntologyCellularComponent	axon cytoplasm	SYBU AP3M1 AP3M2 KIF5B AP3D1	2.86e-04	68	178	5	GO:1904115
GeneOntologyCellularComponent	dendrite cytoplasm	LRRK2 CDKL5 DLG4 KIF5B	3.31e-04	39	178	4	GO:0032839
GeneOntologyCellularComponent	Schmidt-Lanterman incisure	PARD3 AKR1B1 CDH1	3.78e-04	17	178	3	GO:0043220
GeneOntologyCellularComponent	side of membrane	TRADD LRRK2 CD109 NCAM2 ITGAE ITGAX MILR1 LEPR TFRC THADA FES LSAMP DLG4 FCRL4 FGG ATP1B2 CDH1 ENPEP	5.01e-04	875	178	18	GO:0098552
GeneOntologyCellularComponent	compact myelin	PARD3 AKR1B1 CDH1	7.21e-04	21	178	3	GO:0043218
GeneOntologyCellularComponent	AP-type membrane coat adaptor complex	AP3M1 AP4E1 AP3M2 AP3D1	7.38e-04	48	178	4	GO:0030119
GeneOntologyCellularComponent	lateral loop	PARD3 CDH1	1.47e-03	7	178	2	GO:0043219
GeneOntologyCellularComponent	site of polarized growth	LRRK2 CBL CDKL5 FRY DOCK7 DLG3 KIF5B PARD3	1.50e-03	253	178	8	GO:0030427
Domain	ALDOKETO_REDUCTASE_1	AKR1B10 AKR1B15 AKR1B1	9.40e-05	10	176	3	PS00798
Domain	ALDOKETO_REDUCTASE_2	AKR1B10 AKR1B15 AKR1B1	9.40e-05	10	176	3	PS00062
Domain	ALDOKETO_REDUCTASE_3	AKR1B10 AKR1B15 AKR1B1	9.40e-05	10	176	3	PS00063
Domain	Aldo/ket_reductase_CS	AKR1B10 AKR1B15 AKR1B1	9.40e-05	10	176	3	IPR018170
Domain	Aldo/keto_reductase	AKR1B10 AKR1B15 AKR1B1	9.40e-05	10	176	3	IPR020471
Domain	ARM-like	SMG1 NEK10 HEATR4 LRRK2 DOCK10 AP4E1 ARID2 WDFY3 AP3D1 IPO11	2.50e-04	270	176	10	IPR011989
Domain	DUF4211	CCDC82 QSER1	2.63e-04	3	176	2	PF13926
Domain	REELIN	RELN FRRS1	2.63e-04	3	176	2	PS51019
Domain	DUF4211	CCDC82 QSER1	2.63e-04	3	176	2	IPR025451
Domain	Reeler_dom	RELN FRRS1	2.63e-04	3	176	2	IPR002861
Domain	Reeler	RELN FRRS1	2.63e-04	3	176	2	PF02014
Domain	ARM-type_fold	SMG1 NEK10 HEATR4 LRRK2 AP4E1 THADA ARID2 WDFY3 ARMH3 AP3D1 IPO11	3.83e-04	339	176	11	IPR016024
Domain	-	AKR1B10 AKR1B15 AKR1B1	4.21e-04	16	176	3	3.20.20.100
Domain	NADP_OxRdtase_dom	AKR1B10 AKR1B15 AKR1B1	5.08e-04	17	176	3	IPR023210
Domain	Aldo_ket_red	AKR1B10 AKR1B15 AKR1B1	5.08e-04	17	176	3	PF00248
Domain	Aldo/ket_red/Kv-b	AKR1B10 AKR1B15 AKR1B1	5.08e-04	17	176	3	IPR001395
Domain	MAGUK_N_PEST	DLG3 DLG4	5.23e-04	4	176	2	PF10608
Domain	PDZ_assoc	DLG3 DLG4	5.23e-04	4	176	2	PF10600
Domain	DLG1_PEST_dom	DLG3 DLG4	5.23e-04	4	176	2	IPR019590
Domain	PDZ_assoc	DLG3 DLG4	5.23e-04	4	176	2	IPR019583
Domain	MAGUK_N_PEST	DLG3 DLG4	5.23e-04	4	176	2	SM01277
Domain	DLG1	DLG3 DLG4	5.23e-04	4	176	2	IPR016313
Domain	3'-5'_exonuclease_dom	WRN EXD2	8.67e-04	5	176	2	IPR002562
Domain	35EXOc	WRN EXD2	8.67e-04	5	176	2	SM00474
Domain	DNA_pol_A_exo1	WRN EXD2	8.67e-04	5	176	2	PF01612
Domain	-	WRN PNLDC1 EXD2 POLQ	9.91e-04	47	176	4	3.30.420.10
Domain	-	FOXN2 WRN ORC1 FOXP4 GTF2F2 ARID2 SHPRH SMARCC2	1.10e-03	218	176	8	1.10.10.10
Domain	GUANYLATE_KINASE_2	TJP1 DLG3 DLG4	1.27e-03	23	176	3	PS50052
Domain	GUANYLATE_KINASE_1	TJP1 DLG3 DLG4	1.27e-03	23	176	3	PS00856
Domain	Clathrin_mu_CS	AP3M1 AP3M2	1.29e-03	6	176	2	IPR018240
Domain	CLAT_ADAPTOR_M_1	AP3M1 AP3M2	1.29e-03	6	176	2	PS00990
Domain	CLAT_ADAPTOR_M_2	AP3M1 AP3M2	1.29e-03	6	176	2	PS00991
Domain	DUF3398	DOCK10 DOCK7	1.29e-03	6	176	2	PF11878
Domain	DOCK_C/D_N	DOCK10 DOCK7	1.29e-03	6	176	2	IPR021816
Pathway	REACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR	RASGRF2 DLG3 DLG4 LRRC7	2.18e-05	20	120	4	M17670
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_1_PROMOTER	BDP1 POLR3K GTF3C4 POLR3A	7.53e-05	27	120	4	MM15457
Pathway	REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION_INITIATION_FROM_TYPE_1_PROMOTER	BDP1 POLR3K GTF3C4 POLR3A	8.73e-05	28	120	4	M27716
Pathway	REACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING	RASGRF2 DLG3 DLG4 LRRC7	8.73e-05	28	120	4	M837
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SMG1 ARHGAP32 FAT4 MXRA5 RASA2 TTLL9 ZDBF2 NEB CBL BABAM2 AP3M1 RAD51AP2 TBC1D32 PARP4 GSE1 ARID2 SMARCC2 WDFY3 FER1L5	1.20e-09	638	181	19	31182584
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ARHGAP32 DMXL2 NCAM2 AP3M1 DHX15 CDKL5 TJP1 VCAN AKR1B10 EIF4E SCAPER DOCK7 KNDC1 SMARCC2 MACF1 DLG3 LSAMP DLG4 LRRC7 TANC1 KIF5B FGG AKR1B1 TNR AP3D1 WNK2	3.07e-08	1431	181	26	37142655
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BDP1 RASGRF2 NEB AP3M1 GTF3C4 GTF2F2 VPS13D HP ARID2 SHPRH HERC1 ARMH3 AP3D1 HYDIN IPO11	6.07e-08	497	181	15	36774506
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	BDP1 FHIP1B GREB1L THADA DOCK7 KNDC1 TANC1 WNK2	6.66e-08	102	181	8	11214970
Pubmed	Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes.	AKR1B10 AKR1B15 AKR1B1	1.39e-07	3	181	3	17381426
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FAT4 LRRK2 WRN RNF213 AP4E1 CDKL5 THADA FRRS1 DENND6A DTWD2 UBR5 TJP1 EXD2 DOCK7 DLG3 GOLGA5 PARD3 AP3D1	1.50e-07	777	181	18	35844135
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 DMXL2 GABBR2 HDAC3 TDRD3 FRY UBR5 TJP1 DOCK7 SMARCC2 MACF1 DLG3 DLG4 LRRC7 KIF5B QSER1 WDFY3 PARD3 TNR WNK2	1.71e-07	963	181	20	28671696
Pubmed	Interaction network of human early embryonic transcription factors.	TFRC HDAC3 PCGF6 FOXP4 ZZZ3 GSE1 ARID2 MITF SMARCC2 QSER1 CDH1 PHF10	3.58e-07	351	181	12	38297188
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	ARHGAP32 GABBR2 CDKL5 UBR5 STARD9 VCAN MACF1 DLG3 DLG4 LRRC7 PARD3 TNR AP3D1	4.66e-07	430	181	13	32581705
Pubmed	APC/Cdh1 targets PECAM-1 for ubiquitination and degradation in endothelial cells.	CCNA2 FZR1 CDH1	5.52e-07	4	181	3	31489637
Pubmed	Efficient terminal erythroid differentiation requires the APC/C cofactor Cdh1 to limit replicative stress in erythroblasts.	FZR1 COMMD10 CDH1	5.52e-07	4	181	3	35729193
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	CDKL5 TJP1 KNDC1 MACF1 DLG3 DLG4 LRRC7 LSM11 TANC1	1.01e-06	197	181	9	36604605
Pubmed	Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.	TJP1 DLG3 DLG4 CDH1	1.23e-06	16	181	4	21920314
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ARHGAP32 AP4E1 TJP1 NUP133 MACF1 LRRC7 TANC1 GOLGA5 PARD3 AP3D1	1.34e-06	263	181	10	34702444
Pubmed	Comparisons of genomic structures and chromosomal locations of the mouse aldose reductase and aldose reductase-like genes.	AKR1B10 AKR1B15 AKR1B1	1.38e-06	5	181	3	10092857
Pubmed	Association analysis between schizophrenia and the AP-3 complex genes.	AP3M1 AP3M2 AP3D1	1.38e-06	5	181	3	19481122
Pubmed	Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules.	GPD1 PAPSS2 SLC3A1 VCAN LTBP1 ENPEP	1.67e-06	69	181	6	21491542
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 ARHGAP32 DMXL2 RNF213 DGKD ALPK1 PARP4 VPS13D AHRR THADA ARID2 SCAPER MACF1	2.13e-06	493	181	13	15368895
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	DMXL2 LYPLAL1 ALPK1 ORC1 AP4E1 HDAC3 FRRS1 ZZZ3 BRDT GLDC ARID2 COMMD10 DLG3 DLG4 LSM11 LTBP1 DOT1L HERC1 ARMH3 CDH1 RAPGEFL1	2.28e-06	1242	181	21	30973865
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	GPD1 SMG1 DMXL2 RASGRF2 DGKD NEB DHX15 PCGF6 PARP4 GSE1 NUP133 MACF1 PARD3	2.32e-06	497	181	13	23414517
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RASA2 DOCK10 DGKD VPS26A PAPSS2 GTF3C4 POLR3A TFRC CDC45 DHX15 ORC1 PCGF6 UBR5 NUP133 SMARCC2 MACF1 PRR14L TANC1 KIF5B WDFY3 PARD3 AP3D1	2.42e-06	1353	181	22	29467282
Pubmed	Leptin induces hippocampal synaptogenesis via CREB-regulated microRNA-132 suppression of p250GAP.	ARHGAP32 LEPR DOCK7	2.74e-06	6	181	3	24877561
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	PRUNE2 DMXL2 FHIP1B AP3M1 TFRC AP4E1 DENND6A AP3M2 WDFY3 AP3D1	2.75e-06	285	181	10	34369648
Pubmed	E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions.	TJP1 PARD3 CDH1 CDH3	3.96e-06	21	181	4	15775979
Pubmed	Characterization of the adaptor-related protein complex, AP-3.	AP3M1 AP3M2 AP3D1	4.78e-06	7	181	3	9151686
Pubmed	New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity.	TJP1 PARD3 CDH1 CDH3	5.82e-06	23	181	4	18809908
Pubmed	Association of the AP-3 adaptor complex with clathrin.	AP3M1 AP3M2 AP3D1	7.62e-06	8	181	3	9545220
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 DMXL2 SAMD9 DOCK10 PAPSS2 POLR3A CDC45 FREM2 PARP4 GSE1 DOCK7 TANC1 QSER1 AP3D1	8.76e-06	650	181	14	38777146
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	SELENOP CD109 LEPR TFRC FREM2 HP FGG KLKB1 ENPEP	8.89e-06	257	181	9	16335952
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	OFD1 ZDBF2 TDRD3 VPS13D UBR5 DOCK7 MACF1 TANC1	1.49e-05	209	181	8	36779422
Pubmed	HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes.	AP3M1 AP3M2 AP3D1	1.62e-05	10	181	3	18076669
Pubmed	Endoreduplication of the mouse genome in the absence of ORC1.	CCNA2 ORC1 PRL	1.62e-05	10	181	3	29967292
Pubmed	Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.	GPD1 FAT4 CDH1	1.62e-05	10	181	3	18604206
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ARHGAP32 DMXL2 NCAM2 UBR5 MACF1 DLG3 DLG4 LRRC7 TNR	1.81e-05	281	181	9	28706196
Pubmed	Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation.	FAT4 TJP1 CDH1	2.22e-05	11	181	3	26114487
Pubmed	Multicellular rosettes link mesenchymal-epithelial transition to radial intercalation in the mouse axial mesoderm.	TJP1 PARD3 CDH1	2.22e-05	11	181	3	37080203
Pubmed	An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin.	HHIP CDH1 CDH3	2.22e-05	11	181	3	26256211
Pubmed	RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the beta-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling.	ARHGAP32 DLG4 CDH1	2.22e-05	11	181	3	12531901
Pubmed	The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration.	MITF CDH1 CDH3	2.22e-05	11	181	3	36649236
Pubmed	A Glo1-Methylglyoxal Pathway that Is Perturbed in Maternal Diabetes Regulates Embryonic and Adult Neural Stem Cell Pools in Murine Offspring.	LEPR DOCK7 PARD3	2.22e-05	11	181	3	27760310
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RNF213 RSBN1 FOXP4 THADA ZZZ3 GSE1 BRDT UBR5 ARID2 SCAPER SMARCC2 MACF1 DLG4 TANC1 WDFY3 PARD3 PHF10 TCTN2	2.35e-05	1116	181	18	31753913
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 SMG1 DMXL2 DOCK10 ALPK1 UBR5 MACF1 WDFY3	2.54e-05	225	181	8	12168954
Pubmed	Aldose reductase (AC)n gene polymorphism and susceptibility to diabetic retinopathy in Type 2 diabetes in Caucasians.	AKR1B10 AKR1B1	2.69e-05	2	181	2	15745835
Pubmed	Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.	AKR1B10 AKR1B15	2.69e-05	2	181	2	25120755
Pubmed	Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10.	AKR1B10 AKR1B15	2.69e-05	2	181	2	21087085
Pubmed	Impaired biomechanical properties of diabetic skin implications in pathogenesis of diabetic wound complications.	LEPR DOCK7	2.69e-05	2	181	2	21514435
Pubmed	A murine model of phosphate nephropathy.	LEPR DOCK7	2.69e-05	2	181	2	21514417
Pubmed	Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland.	AKR1B10 AKR1B15	2.69e-05	2	181	2	8526877
Pubmed	AKR1B8 deficiency drives severe DSS-induced acute colitis through invasion of luminal bacteria and activation of innate immunity.	AKR1B10 AKR1B15	2.69e-05	2	181	2	36518763
Pubmed	Molecular mechanism by which pioglitazone preserves pancreatic beta-cells in obese diabetic mice: evidence for acute and chronic actions as a PPARgamma agonist.	LEPR DOCK7	2.69e-05	2	181	2	19920213
Pubmed	Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.	LEPR DOCK7	2.69e-05	2	181	2	25071027
Pubmed	Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy.	LEPR DOCK7	2.69e-05	2	181	2	28094765
Pubmed	Microenvironmental regulation of epithelial-mesenchymal transitions in cancer.	VCAN CDH1	2.69e-05	2	181	2	23002209
Pubmed	Expression and functional role of E- and P-cadherins in mouse mammary ductal morphogenesis and growth.	CDH1 CDH3	2.69e-05	2	181	2	7781895
Pubmed	Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies.	DLG3 DLG4	2.69e-05	2	181	2	17344405
Pubmed	Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice.	AKR1B10 AKR1B15	2.69e-05	2	181	2	33644071
Pubmed	Aldo Keto Reductases AKR1B1 and AKR1B10 in Cancer: Molecular Mechanisms and Signaling Networks.	AKR1B10 AKR1B1	2.69e-05	2	181	2	33945128
Pubmed	Mucoepidermoid carcinoma of the thyroid: a tumour histotype characterised by P-cadherin neoexpression and marked abnormalities of E-cadherin/catenins complex.	CDH1 CDH3	2.69e-05	2	181	2	12021924
Pubmed	Decreased levels of AKR1B1 and AKR1B10 in cancerous endometrium compared to adjacent non-cancerous tissue.	AKR1B10 AKR1B1	2.69e-05	2	181	2	23146748
Pubmed	Prevention of diabetes in db/db mice by dietary soy is independent of isoflavone levels.	LEPR DOCK7	2.69e-05	2	181	2	22962258
Pubmed	Regulation of E- and P-cadherin expression correlated with melanocyte migration and diversification.	CDH1 CDH3	2.69e-05	2	181	2	10545227
Pubmed	Amelioration of diabetic nephropathy by SGLT2 inhibitors independent of its glucose-lowering effect: A possible role of SGLT2 in mesangial cells.	LEPR DOCK7	2.69e-05	2	181	2	30886225
Pubmed	Differential spatiotemporal expression of E- and P-cadherin during mouse tooth development.	CDH1 CDH3	2.69e-05	2	181	2	8619966
Pubmed	Functional expression of novel human and murine AKR1B genes.	AKR1B10 AKR1B15	2.69e-05	2	181	2	21276782
Pubmed	Impaired local production of proresolving lipid mediators in obesity and 17-HDHA as a potential treatment for obesity-associated inflammation.	LEPR DOCK7	2.69e-05	2	181	2	23349501
Pubmed	Compensatory upregulation of aldo-keto reductase 1B10 to protect hepatocytes against oxidative stress during hepatocarcinogenesis.	AKR1B10 AKR1B15	2.69e-05	2	181	2	31911858
Pubmed	Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells.	COMMD10 KIF5B	2.69e-05	2	181	2	32286311
Pubmed	Identification of a physiologic vasculogenic fibroblast state to achieve tissue repair.	LEPR DOCK7	2.69e-05	2	181	2	36854749
Pubmed	Reciprocal altered expression of E-cadherin and P-cadherin in mucous membrane pemphigoid.	CDH1 CDH3	2.69e-05	2	181	2	21781454
Pubmed	Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. II. Skin morphogenesis.	CDH1 CDH3	2.69e-05	2	181	2	2806126
Pubmed	Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. I. Lung epithelial morphogenesis.	CDH1 CDH3	2.69e-05	2	181	2	2806125
Pubmed	The effects of designed angiopoietin-1 variant on lipid droplet diameter, vascular endothelial cell density and metabolic parameters in diabetic db/db mice.	LEPR DOCK7	2.69e-05	2	181	2	22430141
Pubmed	The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes.	LEPR DOCK7	2.69e-05	2	181	2	21340625
Pubmed	Erythropoietin ameliorates podocyte injury in advanced diabetic nephropathy in the db/db mouse.	LEPR DOCK7	2.69e-05	2	181	2	23825071
Pubmed	Arid2 regulates hematopoietic stem cell differentiation in normal hematopoiesis.	ARID2 COMMD10	2.69e-05	2	181	2	33346030
Pubmed	Conditioned Medium from Early-Outgrowth Bone Marrow Cells Is Retinal Protective in Experimental Model of Diabetes.	LEPR DOCK7	2.69e-05	2	181	2	26836609
Pubmed	Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: role of Trp112 (Trp111).	AKR1B10 AKR1B1	2.69e-05	2	181	2	24100137
Pubmed	Decreased expression of E-cadherin and ZO-1 in the nasal mucosa of patients with allergic rhinitis: Altered regulation of E-cadherin by IL-4, IL-5, and TNF-alpha.	TJP1 CDH1	2.69e-05	2	181	2	27216347
Pubmed	TGF-β1 promotes cell migration in hepatocellular carcinoma by suppressing reelin expression.	RELN LTBP1	2.69e-05	2	181	2	30447345
Pubmed	Leucine-rich repeat kinase 2 exacerbates neuronal cytotoxicity through phosphorylation of histone deacetylase 3 and histone deacetylation.	LRRK2 HDAC3	2.69e-05	2	181	2	27798112
Pubmed	GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy.	LEPR DOCK7	2.69e-05	2	181	2	23467425
Pubmed	Novel locus for fibrinogen in 3' region of LEPR gene in island population of Vis (Croatia).	LEPR FGG	2.69e-05	2	181	2	25296580
Pubmed	Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.	AKR1B10 AKR1B1	2.69e-05	2	181	2	28929377
Pubmed	Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.	LEPR DOCK7	2.69e-05	2	181	2	32663313
Pubmed	Isolation of placental cadherin cDNA: identification of a novel gene family of cell-cell adhesion molecules.	CDH1 CDH3	2.69e-05	2	181	2	3428270
Pubmed	1.7 A structure of FR-1, a fibroblast growth factor-induced member of the aldo-keto reductase family, complexed with coenzyme and inhibitor.	AKR1B10 AKR1B15	2.69e-05	2	181	2	7578036
Pubmed	A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice.	LEPR DOCK7	2.69e-05	2	181	2	31896565
Pubmed	Rho-kinase regulation of TNF-α-induced nuclear translocation of NF-κB RelA/p65 and M-CSF expression via p38 MAPK in mesangial cells.	LEPR DOCK7	2.69e-05	2	181	2	25007875
Pubmed	Characterization of the promoter of the gene for a mouse vas deferens protein related to the aldo-keto reductase superfamily: effect of steroid hormones and phorbol esters.	AKR1B10 AKR1B15	2.69e-05	2	181	2	8541228
Pubmed	Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway.	AKR1B10 AKR1B1	2.69e-05	2	181	2	32628753
Pubmed	Human aldose reductase and human small intestine aldose reductase are efficient retinal reductases: consequences for retinoid metabolism.	AKR1B10 AKR1B1	2.69e-05	2	181	2	12732097
Pubmed	Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity.	LEPR DOCK7	2.69e-05	2	181	2	29684505
Pubmed	Similarities in structure and expression between mouse P-cadherin, chicken B-cadherin and frog XB/U-cadherin.	CDH1 CDH3	2.69e-05	2	181	2	7743137
Pubmed	Zonula occludens-1 and E-cadherin are coordinately expressed in the mouse uterus with the initiation of implantation and decidualization.	TJP1 CDH1	2.69e-05	2	181	2	10191061
Pubmed	The N-terminal region of reelin regulates postnatal dendritic maturation of cortical pyramidal neurons.	RELN HTR3A	2.69e-05	2	181	2	19366679
Pubmed	Syntabulin-mediated anterograde transport of mitochondria along neuronal processes.	SYBU KIF5B	2.69e-05	2	181	2	16157705
Pubmed	Clustered gene expression changes flank targeted gene loci in knockout mice.	DLG3 DLG4	2.69e-05	2	181	2	18074027
Pubmed	Impaired self-renewal and increased colitis and dysplastic lesions in colonic mucosa of AKR1B8-deficient mice.	AKR1B10 AKR1B15	2.69e-05	2	181	2	25538260
Pubmed	Differential Expression of E-Cadherin and P-Cadherin in Breast Cancer Molecular Subtypes.	CDH1 CDH3	2.69e-05	2	181	2	32988879
Pubmed	Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds.	AKR1B10 AKR1B1	2.69e-05	2	181	2	21329684
Interaction	FMR1 interactions	SMG1 DGKD CDKL5 HDAC3 FZR1 TDRD3 TJP1 GLDC EIF4E DOCK7 SMARCC2 MACF1 DLG4 KIF5B WDFY3 DOT1L PARD3 TNR	1.59e-06	536	180	18	int:FMR1
Interaction	CNKSR2 interactions	CDKL5 TJP1 DLG3 DLG4 LRRC7 TNR	2.72e-05	66	180	6	int:CNKSR2
Interaction	RNF43 interactions	ARHGAP32 AP4E1 UBR5 TJP1 EXD2 NUP133 MACF1 LRRC7 TANC1 GOLGA5 PARD3 CDH1 ENPEP AP3D1	3.12e-05	427	180	14	int:RNF43
Interaction	LURAP1 interactions	CCHCR1 OFD1 FNDC5 DOCK10 ZDBF2 TCEANC POLR3A PCGF6	3.25e-05	137	180	8	int:LURAP1
Interaction	TNIK interactions	ARHGAP32 CDKL5 TDRD3 GSE1 TJP1 DOCK7 SMARCC2 MACF1 DLG3 DLG4 LRRC7 KIF5B TNR	4.01e-05	381	180	13	int:TNIK
Interaction	SLC6A4 interactions	ARHGAP32 DGKD GABBR2 CDKL5 UBR5 STARD9 VCAN MACF1 DLG3 DLG4 LRRC7 PARD3 TNR AP3D1	4.02e-05	437	180	14	int:SLC6A4
Interaction	C2CD4B interactions	FAT4 LRP1B FREM2 MACF1 HERC1	4.40e-05	44	180	5	int:C2CD4B
Interaction	YWHAZ interactions	BDP1 ARHGAP32 DMXL2 UBE2L6 RASGRF2 LRRK2 FNDC5 NCAM2 NEB ATAT1 CBL SLC3A1 FZR1 VPS13D TJP1 STARD9 DOCK7 MACF1 DLG4 PRR14L TANC1 KIF5B WDFY3 PARD3 AKR1B1 CDH1 WNK2	4.55e-05	1319	180	27	int:YWHAZ
Interaction	UCN3 interactions	FAT4 CD109 FREM2 HERC1	4.77e-05	23	180	4	int:UCN3
GeneFamily	Aldo-keto reductases	AKR1B10 AKR1B15 AKR1B1	1.08e-04	15	115	3	399
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	CD109 CDCP1 ITGAE ITGAX LEPR TFRC KEL FCRL4 CDH1 ENPEP	2.10e-04	394	115	10	471
GeneFamily	CD molecules\|Type I classical cadherins	CDH1 CDH3	3.96e-04	5	115	2	1185
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	TJP1 DLG3 DLG4	5.86e-04	26	115	3	904
Coexpression	GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_DN	RASA2 TFRC DHX15 PCGF6 ZZZ3 CCDC82 LACTB2 HP AKR1B15 GOLGA5	1.20e-06	199	179	10	M4059
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	BDP1 RELN LRRK2 FNDC5 GALNT12 SYBU NEB GABBR2 LRP1B TBC1D32 FRY GSE1 VCAN CBLN2 SMARCC2 DLG3 LSAMP LRRC7 LSM11 HERC1 HYDIN NXPH2	7.15e-06	1106	179	22	M39071
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	BDP1 LYPLAL1 WRN DOCK10 VPS26A PAPSS2 TDRD3 GTF2F2 ZZZ3 FAM111A LACTB2 MITF KIF5B QSER1 POLQ CDH1	1.21e-05	656	179	16	M18979
Coexpression	ONDER_CDH1_SIGNALING_VIA_CTNNB1	PRUNE2 DOCK10 SYBU TFRC VCAN LTBP1	2.44e-05	84	179	6	M15484
Coexpression	NADELLA_PRKAR1A_TARGETS_UP	TJP1 CDH1 CDH3	2.55e-05	9	179	3	MM1230
Coexpression	NADELLA_PRKAR1A_TARGETS_UP	TJP1 CDH1 CDH3	2.55e-05	9	179	3	M1790
Coexpression	GCNP_SHH_UP_LATE.V1_DN	HTR3A CDCP1 ITGAE FRRS1 FAM111A DLG4 MRPL3 WNK2	3.21e-05	178	179	8	M2640
Coexpression	GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN	CCHCR1 FOXN2 BABAM2 CCNA2 SCAPER KNDC1 KIF5B PHF10	7.07e-05	199	179	8	M4847
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN	ABCC1 CD109 CDCP1 ITGAX FREM2 TANC1 CDH1 RAPGEFL1	7.07e-05	199	179	8	M7319
Coexpression	GSE28237_EARLY_VS_LATE_GC_BCELL_UP	FAT4 PAPSS2 TFRC THADA ZZZ3 FAM111A ZPBP2 CDH3	7.32e-05	200	179	8	M4893
Coexpression	GAO_ESOPHAGUS_25W_C1_CILIATED_EPITHELIAL_CELLS	PRUNE2 TTLL9 NEK10 SYBU ATAT1 AP3M2 KNDC1 MACF1 LTBP1 DLEC1 POLQ HYDIN	8.02e-05	459	179	12	M39136
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ABCC1 DMXL2 WRN DHX15 RSBN1 TDRD3 GTF2F2 ZZZ3 GSE1 UBR5 ARHGAP12 EIF4E MITF NUP133 MACF1 WDFY3 PARD3	8.52e-05	856	179	17	M4500
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000	DMXL2 DGKD PNLDC1 SYCP2 BRDT SCAPER HERC1	7.63e-06	85	179	7	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k1_1000
CoexpressionAtlas	MESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst-Confounder_removed-fold2.0_adjp0.05	BDP1 CCHCR1 ABCC1 DMXL2 POLR3K UBE2L6 WRN ZDBF2 GTF3C4 CDC45 GREB1L ORC1 PCGF6 THADA CCDC82 UBR5 ARID2 DOCK7 DLG3 DLG4 LTBP1 QSER1 PARD3 ATP1B2 AKR1B1 CDH3 NXPH2 WNK2 TCTN2	1.75e-05	1479	179	29	PCBC_ratio_MESO-15 amniotic fluid MSC_vs_MESO-15 blastocyst_cfr-2X-p05
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200	RNF213 ALPK1 CBLN1 HHIP VCAN AKR1B10 ATP1B2 ENPEP	2.28e-05	138	179	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_100	CBLN1 HHIP VCAN AKR1B10 ATP1B2 ENPEP	2.34e-05	68	179	6	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_100
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500	DMXL2 OFD1 PNLDC1 TFRC CDC45 ORC1 PCGF6 SYCP2 BRDT LACTB2 GLDC NUP133 CDH1	4.28e-05	406	179	13	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	DMXL2 OFD1 VPS26A PNLDC1 TFRC CDC45 ORC1 PCGF6 GTF2F2 SYCP2 DTWD2 BRDT UBR5 LACTB2 GLDC SCAPER NUP133 CDH1 CDH3	4.44e-05	795	179	19	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#3_top-relative-expression-ranked_100	CBLN1 HHIP VCAN ENPEP	4.55e-05	24	179	4	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k3_100
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100	CBLN1 HHIP VCAN AKR1B10 ATP1B2 ENPEP	5.13e-05	78	179	6	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_100
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	DMXL2 OFD1 RNF213 PNLDC1 ORC1 TBC1D32 PCGF6 GTF2F2 SYCP2 THADA DTWD2 BRDT UBR5 GLDC SCAPER NUP133 HERC1 CDH1 CDH3	5.70e-05	810	179	19	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	SMG1 DMXL2 OFD1 ABHD18 DGKD VPS26A PNLDC1 TFRC CDC45 ORC1 PCGF6 SYCP2 DTWD2 BRDT GLDC SCAPER NUP133 HERC1 CDH1	6.70e-05	820	179	19	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DMXL2 MXRA5 LRRK2 WRN ATAT1 AP4E1 ADPRM RHBDL3 ATP1B2 ENPEP	8.69e-09	197	181	10	4edf043e8f586fd375f56485841fe992a18bf853
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	FAT4 RASGRF2 NCAM2 NAALADL2 GSE1 VCAN MACF1 LSAMP LTBP1 TANC1	8.69e-09	197	181	10	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	droplet-Marrow-BM_(NON-STC)\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2L6 CCNA2 TFRC HP VCAN KEL KIF5B HERC1 RFESD	3.78e-08	172	181	9	6004327045f03d832fdabe6cb2f8b1b1db57789a
ToppCell	droplet-Marrow-BM_(NON-STC)-30m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2L6 CCNA2 TFRC HP VCAN KEL KIF5B HERC1 RFESD	3.78e-08	172	181	9	31c5710fd7ebb221e703545595f5ec0ee3a32bcf
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SELENOP FAT4 DOCK10 NAALADL2 LRP1B LOXL1 VCAN MACF1 LSAMP	1.21e-07	197	181	9	11a4c417f035e554431a8f03be13b5eefa3530c0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 DGKD CBLN1 PARD3 ATP1B2 NXPH2	4.12e-07	166	181	8	688e3c01ffcec01eb7027df6f3bde8fecfb50479
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAM2 NEB HHIP SYCP2 DENND6A STARD9 MACF1 ENPEP	4.72e-07	169	181	8	16c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 CBLN1 AHRR ARSF VCAN PARD3 ATP1B2	7.00e-07	178	181	8	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 ARSF MITF PARD3 ATP1B2 ENPEP	7.30e-07	179	181	8	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	SMG1 RNF213 TFRC UBR5 ARID2 AP3M2 MACF1 HERC1	7.94e-07	181	181	8	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 DGKD CBLN1 ARSF PARD3 ATP1B2	8.27e-07	182	181	8	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 RELN NCAM2 NEB LRP1B FREM2 SYCP2 HYDIN	8.98e-07	184	181	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 RELN NCAM2 NEB LRP1B FREM2 SYCP2 HYDIN	8.98e-07	184	181	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 RELN NCAM2 NEB LRP1B FREM2 SYCP2 HYDIN	8.98e-07	184	181	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN HTR3A DOCK10 ARSF MITF PARD3 ATP1B2	9.36e-07	185	181	8	16e9ccea0e3b95d90dc48ef74206c805681dac0b
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELENOP ARHGAP32 DMXL2 ALPK1 PAPSS2 TFRC VCAN RHBDL3	9.74e-07	186	181	8	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DMXL2 DOCK10 RNF213 TFRC ARID2 SHPRH MACF1 POLQ	9.74e-07	186	181	8	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SELENOP ARHGAP32 DMXL2 ALPK1 PAPSS2 TFRC VCAN RHBDL3	9.74e-07	186	181	8	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SAMD9 RNF213 ORC1 LOXL1 AKR1B10 AKR1B15 PRR14L CDH3	1.01e-06	187	181	8	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 NEB GREB1L MITF LRRC7 LTBP1 TANC1 WNK2	1.06e-06	188	181	8	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 CBLN1 ARSF VCAN PARD3 ATP1B2	1.06e-06	188	181	8	c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 EML6 PAPSS2 GREB1L FRY GLDC DOCK7 CDH1	1.10e-06	189	181	8	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	DMXL2 LRRK2 CD109 DOCK10 ALPK1 CDCP1 ITGAX MITF	1.19e-06	191	181	8	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 DGKD CBLN1 ARSF PARD3 ATP1B2	1.24e-06	192	181	8	3abee376c37c3646da33ac381aa63d50a01607a6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 LTBP1 PARD3 ATP1B2 NXPH2	1.24e-06	192	181	8	f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 VCAN FCRL4 ATP1B2 NXPH2	1.24e-06	192	181	8	63d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 LTBP1 PARD3 ATP1B2 NXPH2	1.24e-06	192	181	8	690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 LTBP1 PARD3 ATP1B2 NXPH2	1.34e-06	194	181	8	6ac759828c41ffa974ee82842162caa959351dd1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 LTBP1 PARD3 ATP1B2 NXPH2	1.34e-06	194	181	8	5d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SELENOP FAT4 DOCK10 LOXL1 VCAN CBLN2 MACF1 LSAMP	1.39e-06	195	181	8	1cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 VCAN FCRL4 ATP1B2 NXPH2	1.39e-06	195	181	8	98ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SELENOP DOCK10 NAALADL2 LRP1B LOXL1 VCAN MACF1 LSAMP	1.50e-06	197	181	8	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPD1 DMXL2 DOCK10 CBL ITGAX TFRC MITF LSAMP	1.56e-06	198	181	8	e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 FBXL17 NAALADL2 UBR5 SCAPER WDFY3 HERC1 PARD3	1.62e-06	199	181	8	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 MXRA5 NCAM2 LEPR AHRR VCAN LSAMP LTBP1	1.68e-06	200	181	8	58b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCell	IIF-Lymphocyte-T_NK-ILC\|IIF / Disease, Lineage and Cell Type	TTLL9 NEB CDCP1 SYCP2 DTWD2 EXD2 FER1L5	4.05e-06	159	181	7	55e4f21548f480ca414c00cbff5ec3b13bafd271
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD1 PRUNE2 SELENOP EML6 MITF FGG CDH3	4.22e-06	160	181	7	0544bc465af208da448858d6e174ff56f2e08a46
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HTR3A PNLDC1 SLC3A1 DTWD2 UBR5 PARD3 CDH1	4.39e-06	161	181	7	9cfbbcd38ec2e75376bbc26001964b6991ad0e21
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NEB LRP1B FREM2 LRRC7 KLKB1 HYDIN WNK2	4.58e-06	162	181	7	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SMG1 RNF213 TFRC AP3M2 MACF1 HERC1 ENPEP	6.53e-06	171	181	7	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCHCR1 EML6 GALNT12 ITGAE MILR1 ARMH3 CDH1	6.78e-06	172	181	7	eba1568d4307e91c94fc616549057cbed8df5840
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 EML6 LRRK2 PARP4 WDFY3 PARD3 HYDIN	7.88e-06	176	181	7	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 CBLN1 AHRR PARD3 ATP1B2	8.18e-06	177	181	7	84116796ca4c7007508c0f1a68a1135c7b922278
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABHD18 ZDBF2 CDCP1 POLR3A SYCP2 ARHGAP12 POLQ	8.18e-06	177	181	7	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	LRP1B VPS13D ARHGAP12 SCAPER WDFY3 HERC1 TNR	8.18e-06	177	181	7	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPSS2 LEPR CCNA2 FRRS1 HP VCAN FES	8.49e-06	178	181	7	be8af4d85b8835a85a168639c37857dcaa6b00bf
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 CBLN1 PARD3 ATP1B2 NXPH2	9.46e-06	181	181	7	062f00736eed96e4f4327615d093558dd7d82b20
ToppCell	HSPCs-Erythroblasts\|World / Lineage and Cell class	CCNA2 TFRC ORC1 KEL ATP1B2 RFESD PHF10	9.46e-06	181	181	7	ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L3_VIP_CBLN1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 CBLN1 PARD3 ATP1B2 NXPH2	9.46e-06	181	181	7	7846c7b33d1b89364c5a704edaa86520db731c89
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 LRRK2 GREB1L PARP4 WDFY3 PARD3 HYDIN	9.81e-06	182	181	7	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	10x5'v1-week_17-19-Hematopoietic-erythroid\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	RELN CYP2W1 TFRC KEL ATP1B2 RFESD CDH1	1.05e-05	184	181	7	0efc757d9512d6a8fe8176e977a94e4494ed9778
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 DGKD FREM2 LTBP1 FCRL4 ATP1B2 NXPH2	1.05e-05	184	181	7	e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 DGKD CBLN1 PARD3 ATP1B2	1.05e-05	184	181	7	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	DMXL2 DOCK10 RNF213 TFRC SHPRH MACF1 POLQ	1.09e-05	185	181	7	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 CBLN1 ARSF PARD3 ATP1B2	1.09e-05	185	181	7	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 CBLN1 ARSF PARD3 ATP1B2	1.09e-05	185	181	7	bdfa8c284bbc5e85c806327fbb7778cf16242a38
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MXRA5 LOXL1 AKR1B10 KEL CDH1 CDH3 RAPGEFL1	1.09e-05	185	181	7	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	LRRK2 FREM2 HHIP TANC1 FGG PARD3 CDH1	1.13e-05	186	181	7	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 EML6 LRRK2 GREB1L FREM2 WDFY3 HYDIN	1.13e-05	186	181	7	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 DGKD GREB1L FREM2 LTBP1 ATP1B2 NXPH2	1.13e-05	186	181	7	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2L6 CCNA2 TFRC CDC45 ORC1 KEL ATP1B2	1.13e-05	186	181	7	ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCell	droplet-Spleen-SPLEEN-30m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBE2L6 CCNA2 TFRC CDC45 ORC1 KEL ATP1B2	1.13e-05	186	181	7	7cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 CBLN1 ARSF PARD3 ATP1B2	1.17e-05	187	181	7	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	CV-Severe-3\|Severe / Virus stimulation, Condition and Cluster	CCHCR1 CD109 LEPR CDC45 ORC1 FES ATP1B2	1.17e-05	187	181	7	68cb43a73945f5e252530da25613f6b3f484b4d5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 DOCK10 CBLN1 ARSF VCAN PARD3 ATP1B2	1.21e-05	188	181	7	6ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 CBLN1 GREB1L PARD3 ATP1B2 NXPH2	1.21e-05	188	181	7	433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DGKD FREM2 UBR5 VCAN MITF TANC1 HYDIN	1.21e-05	188	181	7	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 EML6 PAPSS2 GREB1L FRY GLDC CDH1	1.25e-05	189	181	7	fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DGKD PAPSS2 FREM2 LTBP1 PARD3 ATP1B2 NXPH2	1.30e-05	190	181	7	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 PARD3 ATP1B2 NXPH2	1.30e-05	190	181	7	56cc761e50fddfb5366391518b4d8e16589b6b42
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SELENOP NCAM2 NAALADL2 LRP1B VCAN LSAMP ENPEP	1.30e-05	190	181	7	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 PARD3 ATP1B2 NXPH2	1.30e-05	190	181	7	25d4b591f75c26e404a34c42f1742d580af6598d
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	GPD1 GALNT12 CDCP1 TFRC TDRD3 MITF LSAMP	1.30e-05	190	181	7	4cce4ddb79b7751d0103e10f71156977e0c34439
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD VCAN PARD3 ATP1B2 NXPH2	1.30e-05	190	181	7	be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.34e-05	191	181	7	2b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.34e-05	191	181	7	02e1ae144da7274171e055356d10e8d175c5347f
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	DOCK10 RNF213 TFRC ZZZ3 ARID2 MACF1 POLQ	1.34e-05	191	181	7	9454f642c3621370fa23640b631301346b300950
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 PAPSS2 GREB1L PARD3 ATP1B2 NXPH2	1.34e-05	191	181	7	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	Severe_COVID-19-Myeloid-TRAM3\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.34e-05	191	181	7	05867b96199a46a415848409130697c810d18937
ToppCell	BAL-Severe-Myeloid-TRAM\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.34e-05	191	181	7	4c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCell	BAL-Severe-Myeloid-TRAM\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.34e-05	191	181	7	de7c88bb46f794291025ef121a89fcd94dea4ffe
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 EML6 NCAM2 PAPSS2 GREB1L GLDC CDH1	1.39e-05	192	181	7	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 GREB1L FRY LSAMP LTBP1 TANC1 AKR1B1	1.39e-05	192	181	7	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.39e-05	192	181	7	34505a13b8a47c9286c560122fa7861b9c331a08
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.39e-05	192	181	7	57c1410ebf90c230993e065eb78385daa3360960
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SMG1 DOCK10 RNF213 TFRC AP3M2 MACF1 HERC1	1.39e-05	192	181	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT4 RELN DOCK10 DGKD CBLN1 PARD3 ATP1B2	1.39e-05	192	181	7	6a252e298f8a454623fa9c1c893a7a45a886d694
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 VCAN ATP1B2 NXPH2	1.39e-05	192	181	7	bd3fa6c8fcb618db64d11f25cabaf08608957c35
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD ARHGAP12 MITF PARD3 ATP1B2	1.39e-05	192	181	7	67d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD MITF PARD3 ATP1B2 NXPH2	1.39e-05	192	181	7	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 PARD3 ATP1B2 NXPH2	1.43e-05	193	181	7	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	COVID-19-Myeloid-TRAM1\|Myeloid / Condition, Lineage and Cell class	GPD1 GALNT12 CDCP1 TFRC HP LSAMP AKR1B1	1.43e-05	193	181	7	6e6a7f4e50c8ae70bc187b9ce77140a7049dd288
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 PARD3 ATP1B2 NXPH2	1.43e-05	193	181	7	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	Bronchial_Biopsy-Mesenchymal-Fibroblasts\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	SELENOP MXRA5 LEPR VCAN LSAMP LTBP1	1.47e-05	129	181	6	13cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 LTBP1 ATP1B2 NXPH2	1.48e-05	194	181	7	52aebb0b563e2c2058e7f0554ae870e47692b163
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT4 DOCK10 GSE1 VCAN MACF1 LSAMP TANC1	1.48e-05	194	181	7	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 GREB1L RHBDL3 MITF LTBP1 TANC1 WNK2	1.48e-05	194	181	7	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD PAPSS2 LTBP1 ATP1B2 NXPH2	1.48e-05	194	181	7	bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD MITF PARD3 ATP1B2 NXPH2	1.48e-05	194	181	7	4f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN DOCK10 DGKD MITF PARD3 ATP1B2 NXPH2	1.48e-05	194	181	7	02a9cc821c2b14aa7d0e55661a5fab66364474e1
Disease	Colorectal Carcinoma	ABCC1 SELENOP RASGRF2 CD109 WRN GALNT12 TFRC CDKL5 HHIP ZZZ3 GSE1 AKR1B10 DLG3 CDH1	9.31e-05	702	177	14	C0009402
Disease	Major Depressive Disorder	RELN HTR3A GABBR2 HP DLG3 LSAMP DLG4 ENPEP	1.16e-04	243	177	8	C1269683
Disease	APOE carrier status, cerebral amyloid angiopathy	DOCK10 AP4E1 FZR1 CDH1	1.17e-04	42	177	4	EFO_0006790, EFO_0007659
Disease	FEV/FEC ratio	LYPLAL1 FBXL17 GALNT12 DGKD NEB BABAM2 DHX15 FREM2 HHIP THADA BRDT ARHGAP12 SCAPER LTBP1 DLEC1 HERC1 PARD3 AP3D1 RAPGEFL1	1.56e-04	1228	177	19	EFO_0004713
Disease	Unipolar Depression	RELN HTR3A GABBR2 HP DLG3 LSAMP DLG4 ENPEP	1.80e-04	259	177	8	C0041696
Disease	aldose reductase measurement	AKR1B10 AKR1B1	2.13e-04	4	177	2	EFO_0801364
Disease	iron deficiency anemia (is_marker_for)	TFRC HP	2.13e-04	4	177	2	DOID:11758 (is_marker_for)
Disease	developmental disorder of mental health (implicated_via_orthology)	DLG3 DLG4 TANC1 PARD3	2.15e-04	49	177	4	DOID:0060037 (implicated_via_orthology)
Disease	complex trait	DMXL2 RASA2 BABAM2 LEPR HHIP DOCK7 MACF1 LTBP1	2.44e-04	271	177	8	EFO_0010578
Disease	brain volume measurement	SELENOP RELN TTLL9 GALNT12 CBLN1 PCGF6 HHIP DENND6A LOXL1 VCAN MITF COMMD10	2.68e-04	595	177	12	EFO_0006930
Disease	pulse pressure measurement	MXRA5 LYPLAL1 NEK10 FBXL17 RNF213 CCNA2 DHX15 LOXL1 ARHGAP12 EIF4E FES LTBP1 DLEC1 KIF5B DOT1L ARMH3 FER1L5 ENPEP AP3D1 HYDIN	2.76e-04	1392	177	20	EFO_0005763
Disease	Colorectal Neoplasms	ABCC1 SELENOP CD109 GALNT12 TFRC HHIP AKR1B10 CDH1	2.83e-04	277	177	8	C0009404
Disease	cancer aggressiveness measurement, Gleason score measurement, prostate carcinoma	NAALADL2 KLKB1	3.54e-04	5	177	2	EFO_0001663, EFO_0006999, EFO_0007000
Disease	Rett Syndrome	GABBR2 CDKL5	3.54e-04	5	177	2	C0035372
Disease	Werner syndrome (implicated_via_orthology)	WRN EXD2	3.54e-04	5	177	2	DOID:5688 (implicated_via_orthology)
Disease	Rett Syndrome, Atypical	GABBR2 CDKL5	3.54e-04	5	177	2	C2748910
Disease	partial thromboplastin time	SELENOP FGG KLKB1	3.91e-04	24	177	3	EFO_0004310
Disease	cortical thickness	RELN GALNT12 SYBU AP3M1 HHIP VPS13D THADA VCAN ARHGAP12 MITF DOCK7 MACF1 DLEC1 KIF5B QSER1 PARD3 WNK2	4.06e-04	1113	177	17	EFO_0004840
Disease	coronary artery calcification	BDP1 DMXL2 RASA2 DOCK10 LRP1B FRY STARD9 DOCK7 ARMH3 KLKB1	4.12e-04	450	177	10	EFO_0004723
Disease	cortical surface area measurement	RELN SAMD9 DOCK10 FBXL17 GALNT12 SYBU PCGF6 HHIP LINC01551 THADA LACTB2 TJP1 VCAN ARHGAP12 FES MACF1 QSER1 PARD3 WNK2	4.85e-04	1345	177	19	EFO_0010736
Disease	glucagon measurement, glucose tolerance test	MACF1 HERC1	5.28e-04	6	177	2	EFO_0004307, EFO_0008463
Disease	Mood Disorders	RELN HTR3A HP DLG3 DLG4 PRL	5.48e-04	168	177	6	C0525045
Disease	Agouti-related protein measurement	FZR1 CDH1 CDH3	5.58e-04	27	177	3	EFO_0008016
Disease	chronic obstructive pulmonary disease (is_implicated_in)	ABCC1 LRP1B LEPR HHIP	5.66e-04	63	177	4	DOID:3083 (is_implicated_in)
Disease	diverticular disease	BABAM2 HHIP LACTB2 LOXL1 SCAPER LTBP1 DLEC1	5.81e-04	236	177	7	EFO_0009959
Disease	obesity	EML6 NCAM2 DGKD ZDBF2 ALPK1 LEPR ZZZ3	6.57e-04	241	177	7	EFO_0001073
Disease	magnesium measurement	CCDC168 ALPK1 PAPSS2 DLEC1	6.75e-04	66	177	4	EFO_0004845
Disease	Helicobacter Infections	TFRC CDH1	7.37e-04	7	177	2	C0079487
Disease	smoking status measurement, Crohn's disease	FZR1 CDH1	7.37e-04	7	177	2	EFO_0000384, EFO_0006527
Disease	EAR, PATELLA, SHORT STATURE SYNDROME	CDC45 ORC1	7.37e-04	7	177	2	C1868684
Disease	HbA1c measurement	ABCC1 FOXN2 VPS26A ITGAX TFRC FZR1 THADA MACF1 KEL ATP1B2 CDH1 CDH3	8.18e-04	675	177	12	EFO_0004541
Disease	Ovarian Mucinous Adenocarcinoma	NEK10 LRRK2 ALPK1	8.43e-04	31	177	3	C1335167
Disease	Diabetes Mellitus	ALPK1 LEPR KIF5B	9.26e-04	32	177	3	C0011849
Disease	Unilateral agenesis of kidney	GREB1L FREM2	9.78e-04	8	177	2	C0266294
Disease	benign neoplasm (implicated_via_orthology)	DLG3 DLG4	9.78e-04	8	177	2	DOID:0060072 (implicated_via_orthology)
Disease	symmetrical dimethylarginine measurement	AKR1B10 AKR1B15	1.25e-03	9	177	2	EFO_0006523
Disease	response to methylphenidate	RASGRF2 LSAMP	1.25e-03	9	177	2	GO_0036271
Disease	Coffin-Siris syndrome (implicated_via_orthology)	SMARCC2 PHF10	1.25e-03	9	177	2	DOID:1925 (implicated_via_orthology)
Disease	white matter growth measurement	AKR1B10 AKR1B1	1.25e-03	9	177	2	EFO_0009335
Disease	non-syndromic X-linked intellectual disability (implicated_via_orthology)	THADA DLG3	1.25e-03	9	177	2	DOID:0050776 (implicated_via_orthology)
Disease	alcoholic liver disease	HTR3A DHX15 GLDC LSAMP	1.52e-03	82	177	4	EFO_0008573
Disease	optic disc size measurement	SELENOP LRP1B VCAN MACF1 LTBP1 DLEC1	1.53e-03	205	177	6	EFO_0004832
Disease	venous thromboembolism, factor VII measurement	BABAM2 FGG PARD3	1.53e-03	38	177	3	EFO_0004286, EFO_0004619
Disease	severe acute respiratory syndrome, COVID-19	RELN MXRA5 WRN NCAM2 LRP1B GLDC LSAMP PARD3 TNR	1.58e-03	447	177	9	EFO_0000694, MONDO_0100096
Disease	brain measurement, neuroimaging measurement	GALNT12 HHIP THADA DTWD2 VCAN MITF FES MACF1 PARD3 WNK2	1.88e-03	550	177	10	EFO_0004346, EFO_0004464
Disease	response to statin, myopathy	RASGRF2 CDCP1	1.90e-03	11	177	2	EFO_0004145, GO_0036273
Disease	Complications of Diabetes Mellitus	HP AKR1B1	1.90e-03	11	177	2	C0342257
Disease	Bardet-Biedl syndrome (implicated_via_orthology)	TBC1D32 SCAPER	1.90e-03	11	177	2	DOID:1935 (implicated_via_orthology)
Disease	late-onset Alzheimers disease	SELENOP NEK10 NAALADL2 FZR1 SCAPER DLEC1 CDH1	1.99e-03	292	177	7	EFO_1001870
Disease	neuroimaging measurement	RELN SAMD9 GALNT12 TFRC HHIP LINC01551 THADA VCAN ARHGAP12 MITF MACF1 QSER1 PARD3 WNK2 IPO11	2.05e-03	1069	177	15	EFO_0004346
Disease	survival time, Sepsis	SAMD9 TFRC	2.27e-03	12	177	2	EFO_0000714, HP_0100806
Disease	sialate O-acetylesterase measurement	BTBD2 GOLGA5	2.27e-03	12	177	2	EFO_0803073
Disease	pulmonary embolism (biomarker_via_orthology)	HP FGG	2.27e-03	12	177	2	DOID:9477 (biomarker_via_orthology)
Disease	hepatocellular carcinoma (is_marker_for)	CBL LRP1B HP ARID2 AKR1B1 CDH1 PRL	2.35e-03	301	177	7	DOID:684 (is_marker_for)
Disease	potassium measurement	NEK10 EML6 AP4E1	2.50e-03	45	177	3	EFO_0009283
Disease	Abnormality of refraction	SMG1 ARHGAP32 AP3M1 DHX15 HHIP FRY LOXL1 EXD2 ARID2 DLEC1 PARD3	2.58e-03	673	177	11	HP_0000539
Disease	Squamous cell carcinoma of esophagus	CCHCR1 FAT4 DLEC1 ATP1B2	2.61e-03	95	177	4	C0279626
Disease	hypertension	EML6 RNF213 AKR1B10 FES LRRC7 AKR1B1 ENPEP	2.63e-03	307	177	7	EFO_0000537
Disease	Coffin-Siris syndrome	ARID2 SMARCC2	2.67e-03	13	177	2	C0265338
Disease	Endometrioma	SELENOP LRRK2 VCAN AKR1B1 PRL	2.93e-03	161	177	5	C0269102
Disease	Endometriosis	SELENOP LRRK2 VCAN AKR1B1 PRL	2.93e-03	161	177	5	C0014175
Disease	lung adenocarcinoma (is_implicated_in)	LRP1B UBR5 FES	3.19e-03	49	177	3	DOID:3910 (is_implicated_in)
Disease	platelet storage pool deficiency (implicated_via_orthology)	DOCK7 AP3D1	3.57e-03	15	177	2	DOID:2223 (implicated_via_orthology)
Disease	quinate measurement	LRRK2 LEPR	3.57e-03	15	177	2	EFO_0021167
Disease	Hypogonadotropic hypogonadism	LEPR PRL	3.57e-03	15	177	2	C0271623
Disease	Primary hypogonadism	LEPR PRL	3.57e-03	15	177	2	C0948896
Disease	Hypogonadism, Isolated Hypogonadotropic	LEPR PRL	3.57e-03	15	177	2	C3489396
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	NEK10 FRY PARD3	3.78e-03	52	177	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	comparative body size at age 10, self-reported	GPD1 RELN RASA2 NEK10 VPS26A LRP1B LEPR HHIP	3.99e-03	420	177	8	EFO_0009819
Disease	Hypogonadism	LEPR PRL	4.06e-03	16	177	2	C0020619
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	UBR5 EIF4E	4.06e-03	16	177	2	C0334634
Disease	ankle brachial index	SYBU COMMD10	4.06e-03	16	177	2	EFO_0003912
Disease	reticulocyte count	CCHCR1 FOXN2 EML6 CBL ITGAX TFRC GREB1L FZR1 FOXP4 THADA KEL HERC1 AKR1B1 CDH1	4.33e-03	1045	177	14	EFO_0007986
Disease	granulocyte count	RASA2 EML6 LEPR THADA FCRL4 RAPGEFL1	4.43e-03	254	177	6	EFO_0007987
Disease	Benign neoplasm of stomach	UBR5 CDH1	4.59e-03	17	177	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	UBR5 CDH1	4.59e-03	17	177	2	C0496905
Disease	Astrocytosis	LEPR TNR	4.59e-03	17	177	2	C3887640
Disease	diabetic neuropathy (biomarker_via_orthology)	LRRK2 HHIP	4.59e-03	17	177	2	DOID:9743 (biomarker_via_orthology)
Disease	Carcinoma in situ of stomach	UBR5 CDH1	4.59e-03	17	177	2	C0154060
Disease	Gliosis	LEPR TNR	4.59e-03	17	177	2	C0017639
Disease	polyp of colon	FZR1 CDH1 CDH3	4.66e-03	56	177	3	MONDO_0021400
Disease	hepatocellular carcinoma (is_implicated_in)	LRP1B LEPR ARID2 FES CDH1	4.81e-03	181	177	5	DOID:684 (is_implicated_in)
Disease	cervical carcinoma	PRUNE2 CBLN2 ZPBP2 FCRL4 ARMH3	4.92e-03	182	177	5	EFO_0001061
Disease	heel bone mineral density, urate measurement	EML6 WRN TFRC GLDC IPO11	4.92e-03	182	177	5	EFO_0004531, EFO_0009270
Disease	platelet crit	HEATR4 LRRK2 DOCK10 DGKD BTBD2 CBL ITGAX LEPR THADA GSE1 MITF DOT1L CDH3	5.05e-03	952	177	13	EFO_0007985
Disease	IGA glomerulonephritis	DOCK10 ITGAX FCRL4	5.14e-03	58	177	3	EFO_0004194
Disease	Endometrial Neoplasms	AKR1B10 AKR1B1 CDH1	5.14e-03	58	177	3	C0014170
Disease	type 1 diabetes mellitus (biomarker_via_orthology)	CBL HP	5.72e-03	19	177	2	DOID:9744 (biomarker_via_orthology)
Disease	cognitive function measurement	DMXL2 SAMD9 HEATR4 WRN FBXL17 NCAM2 ZDBF2 NAALADL2 LRP1B DHX15 EXD2 LRRC7 LTBP1 ARMH3 TNR HYDIN WNK2	5.87e-03	1434	177	17	EFO_0008354
Disease	carotid artery intima media thickness	LRRK2 FBXL17 PNLDC1 LRP1B LOXL1 VCAN LRRC7 DLEC1	5.99e-03	450	177	8	EFO_0007117

Protein segments in the cluster

Peptide	Gene	Start	Entry
LKTEPDSRQQVYISH	AHRR	576	A9YTQ3
SQPSVVKNYIQRHTF	C2orf16	951	Q68DN1
NALKEHQETIVPVTY	ARSF	536	P54793
VNKTNETIRHENKPY	BDP1	1656	A6H8Y1
NNVLYSAHDVSPEKV	LINC01551	96	Q86U37
VEQINNTLYPHTSQV	VCAN	2276	P13611
QSHVVSQKILDPIYF	TBC1D32	331	Q96NH3
YQELEHLQTVKNISP	BRDT	741	Q58F21
QQSPEVAQYSGKHQV	CTSL3P	166	Q5NE16
QVLVQHPQNESNKIY	CDCP1	331	Q9H5V8
HPQNESNKIYVVDLS	CDCP1	336	Q9H5V8
KVDTSVHYNIPELQS	GSE1	1056	Q14687
VKRNHNQYVNPSGVA	FAT4	3766	Q6V0I7
VVYSEVKTQHPDNSA	FCRL4	491	Q96PJ5
QNLVSSDYPVHIDKI	ABHD18	46	Q0P651
HQGEVQNYKPLQVVT	HTR3A	141	P46098
ESAVQQKQQHPPTYV	ARID2	1571	Q68CP9
QQALPYTSAVLHEVQ	CYP2W1	341	Q8TAV3
VTNQVECHPYLTQEK	AKR1B10	181	O60218
TNQEKVVIVSHLPIY	ADPRM	231	Q3LIE5
IINHFNPKIESYAAV	ARMH3	596	Q5T2E6
NPKIESYAAVNHISQ	ARMH3	601	Q5T2E6
QQSLQDIYKPGTAQH	ASB14	21	A6NK59
KTVIANPVLYLNNHI	DMXL2	2216	Q8TDJ6
LQQVYNHSVTDPEKL	DOT1L	111	Q8TEK3
SQNLVAIPVYVKHSI	AP3M1	266	Q9Y2T2
RTGHYLTVKDNQVVQ	DHX15	706	O43143
HPKQVQLKTSISSQY	DTWD2	196	Q8NBA8
QRQHKLTIPSIQYTE	EFCAB12	341	Q6NXP0
YLTDPQIHSVDQKVF	ALPK1	1191	Q96QP1
AVNQIECHPYLTQEK	AKR1B1	181	P15121
VTTLPGHIQAVYVQN	AP3D1	511	O14617
TYVIQQDPTLALQHQ	AP4E1	361	Q9UPM8
DPSKICYQEQTQSHV	NXPH2	206	O95156
LRYNTTQKVFHVNNP	RAD51AP2	491	Q09MP3
QVIHTEKPLYVQANN	RASA2	676	Q15283
VKQEPLHSTSYAVNI	QSER1	1291	Q2KHR3
AQTTTVLEKYKVHNP	ITGAX	1091	P20702
LSYQHPSVDQKQIEE	OFD1	861	O75665
TNLSVHEDKNRVPYV	KIF5B	151	P33176
AQNLVAIPVYVKHNI	AP3M2	266	P53677
IQVAHPLVQKQLVDY	FHIP1B	311	Q8N612
QHEIVLKVAYPQADS	NUP133	781	Q8WUM0
QEQNIVPYTIIKDIH	PAPSS2	211	O95340
PKVDYQQVFTRHINQ	LSM11	331	P83369
IQKTSAQPFDLQIYH	LRP1B	1506	Q9NZR2
VEIEKVVLHPNYSQV	HP	231	P00738
TEAHPETKQRVLTNY	LRRC7	411	Q96NW7
HQQNTDLIYQTGPKS	GOLGA5	46	Q8TBA6
HVNYTQPLVAVKFLN	ATP1B2	236	P14415
DPVHTVSLQQFIYEK	IPO11	926	Q9UI26
NIIHTPTKQQQVDYI	KIAA2026	1431	Q5HYC2
INYVQSVHKGVEPVE	FREM2	1146	Q5SZK8
IQVAVHKIYQQLSAT	HERC1	1721	Q15751
KTESNQEVANPEHYI	EIF4E	21	P06730
HVNPKYIVLESDFTN	LOXL1	536	Q08397
SFILEQAVYHNVKPA	COMMD10	76	Q9Y6G5
ISNENYVPHGLKVVQ	EXD2	551	Q9NVH0
KVSYQLQTPEGQTDH	ITGAE	786	P38570
HQVVQENGVYTIAKL	NEK10	406	Q6ZWH5
PVIHNAEAKIQQYIS	LACTB2	201	Q53H82
VSYQGLPVQKTQTIH	LTBP1	521	Q14766
QQVIPHVYPVAAKTQ	LTBP1	541	Q14766
VHEFVVKAVQQYPEN	LRRK2	291	Q5S007
IPQSQYDVVSDHVSK	LEPR	376	P48357
LSPPQYSHQVQVKEE	FOXP4	626	Q8IVH2
VQPEQKHTAEYAANI	ENPEP	311	Q07075
VFQTYTNKSHVPIEA	PARP4	641	Q9UKK3
QYQPHGKRQSSVTVV	ARHGAP32	2006	A7KAX9
KQRIHTVTVDNGNIY	RFESD	116	Q8TAC1
ETFHIYQPQLTVARK	GREB1L	666	Q9C091
SYKHLFQPVINQVVD	HDAC3	231	O15379
HPAKQTVEAYSAAVQ	MACF1	751	Q9UPN3
KHSQELQYATPVFQE	MILR1	306	Q7Z6M3
SEKIAQNQIHVQYST	RELN	2766	P78509
EKETGNIAVHTVYQN	ARHGAP12	816	Q8IWW6
PHQVYVQILQKLTGQ	ORC1	576	Q13415
FDLQTHVIQVPQGKY	PHF10	226	Q8WUB8
NEKIHLISTQSAIPY	FGG	256	P02679
SPVQQYTEHLAAVKA	FZR1	346	Q9UM11
VENYSNVSIHLKNPE	CCDC82	406	Q8N4S0
KYQPNIDVQESIHFL	CD109	1061	Q6YHK3
HRPVNVVNVYNDTQI	CDC45	101	O75419
ITLEAHQQNKPYEIT	HYDIN	4676	Q4G0P3
KIENPSQEIVAKYHT	AWAT2	291	Q6E213
FHVVKVYNRQTIQVS	CBLN1	116	P23435
HNQKEAVILYAQPSE	C1QTNF6	211	Q9BXI9
KHDQIASQEYNIPIA	DOCK10	796	Q96BY6
YHVSCQQKQNTPLET	DOCK7	651	Q96N67
PQVCHLLTNKVQYVI	BABAM2	251	Q9NXR7
APNHTQFLVTVVEKY	FRRS1	136	Q6ZNA5
QKIVHNPDVITYDTE	FAM111A	521	Q96PZ2
VNEVTVEQLVQQYPH	FBXL17	656	Q9UF56
PINQYLRKQSHEQTS	POLQ	1191	O75417
LYNTNDIIHTPQIRK	HEATR4	96	Q86WZ0
SFHVVKVYNRQTIQV	CBLN2	146	Q8IUK8
QAVEVIYPQHSKLTD	DENND6A	76	Q8IWF6
TSQKEIRYNTHQPEG	GALNT12	491	Q8IXK2
KYVGEQVPSEVHSQT	CCHCR1	251	Q8TD31
NQHIPGDNSIYITKI	DLG3	246	Q92796
QHIPGDNSIYVTKII	DLG4	181	P78352
TEIINTQHENVKYLP	GPD1	51	P21695
NQDLTFQHIKIIYPT	LYPLAL1	46	Q5VWZ2
FLNKHYNLETTVPQV	ATAT1	166	Q5SQI0
LKTVQNREHFEPTQY	DGKD	141	Q16760
LQDTPEKTTYIKQNH	GABBR2	816	O75899
LSPHYLSSVIKQNQV	FOXN2	216	P32314
TPFSQIKEIIIHQNY	KLKB1	461	P03952
AKVVSQVHAFQENPY	KNDC1	1676	Q76NI1
TPQDHIKVTQEQYEL	CBL	356	P22681
TVNQHPKYRNVVATS	EML6	1421	Q6ZMW3
QVSTGAYKRQVHEVP	EML6	1831	Q6ZMW3
HKEQNPYVVQSIISL	FRY	256	Q5TBA9
YINHNQESIKSQPES	CCDC168	321	Q8NDH2
QTYLKAPQHAQQSIR	CCNA2	396	P20248
SIHGPTDYQVNIQII	BTBD2	411	Q9BX70
NEKQSRHSYIDTIPQ	CDKL5	461	O76039
AEVQKPHVYLQSSQV	DLEC1	961	Q9Y238
LIHQLTVYVPDENNT	SCAPER	1021	Q9BY12
KNQHTLYVEVTNEAP	CDH3	401	P22223
YTQELTKPNIQEHKV	C18orf63	316	Q68DL7
AKQQYILHVAVTNVV	CDH1	446	P12830
RNIHYNSVVNPNKAT	OTUD5	331	Q96G74
QPHRTCKKVSYQEQI	PRR14L	1521	Q5THK1
PHIVQYQANKVTHTL	PPEF2	531	O14830
KCNIVVHQTQPLYNI	PCGF6	171	Q9BYE7
HVVPAANKEQYEQLS	PARD3	356	Q8TEW0
HVAIKGSVAYVPQQA	ABCC1	701	P33527
INTKHNIIYVNGSVP	MRPL3	276	P09001
QEARILKQYSHPNIV	FES	606	P07332
IVSQVHPETKENEIY	PRL	161	P01236
LKQYHPVVEATQNTE	RSBN1	701	Q5VWQ0
DKVVTTNYKPVANHQ	GTF2F2	146	P13984
TDGVSQIHYIKQIVP	THADA	46	Q6YHU6
IEKHFNVNTDYQNPV	TDRD3	471	Q9H7E2
YQEKNEHDISATVQP	PRUNE2	1661	Q8WUY3
VAPVKVHQYDQFVPS	SAXO1	81	Q8IYX7
VVLSDAYAHPQQKVA	TRADD	26	Q15628
KEQRVAYAQVPAHSV	FER1L5	706	A0AVI2
CSVQTQHEPKTSQVY	LSAMP	111	Q13449
QHEPKTSQVYLIVQV	LSAMP	116	Q13449
GQPTEEIQQYKVLVH	NBPF8	51	Q3BBV2
QFVLQVTHPRYLKNS	RHBDL3	186	P58872
QQTSYRIDHQPKVAQ	RASGRF2	1196	O14827
EQYILVTNKCHPDQT	SAMD9	411	Q5K651
YIVHVQAISIQGQSP	FNDC5	101	Q8NAU1
PGVSEQQVYHKFQNL	PNLDC1	431	Q8NA58
HAVYQAVLSLKNIPV	SMG1	546	Q96Q15
QAHIQVVSKNLYSQD	POLR3A	31	O14802
EAQQALYPVQQTIHE	SHPRH	1116	Q149N8
SDYHTVNVDVQKTQP	SLC3A1	531	Q07837
LYQESISKQQPHISN	TANC1	1826	Q9C0D5
TKEHCYNQVPVELST	WRN	1086	Q14191
QGLSQHVVTNYKQVI	STARD9	186	Q9P2P6
QNVKHPVTGQFLYQD	TFRC	511	P02786
TVTEDKNNASHVVYP	SMARCC2	166	Q8TAQ2
VVEYTVSRKNPHQVD	HHIP	321	Q96QV1
KVSEHIPVYQQEENQ	SELENOP	106	P49908
VTNQVECHPYLTQEK	AKR1B15	181	C9JRZ8
QYQKVPVLFHLDVTS	RNF213	2046	Q63HN8
AQKVYLSNLTLQHIP	SUN5	266	Q8TC36
YQSSKLIFPENIHIQ	ZNF519	191	Q8TB69
YQFSRAHKTVPQQVA	WDFY3	2101	Q8IZQ1
HYLPQVIDGTQTNKI	TCEANC	281	Q8N8B7
THLENPTKYHIQQAQ	MITF	121	O75030
QPHIIQLKNETTYEN	NCAM2	301	O15394
QYLTPLQQKEVTVRH	SYBU	266	Q9NX95
EIESPHINENYIQSK	SYCP2	1231	Q9BX26
TTKIYHPNVDENGQI	UBE2L6	71	O14933
TSSKEQPVVFNHVYN	TNR	56	Q92752
VPHYSVTEPQVAVNK	ZDBF2	1006	Q9HCK1
YVSNIPLQSVIKQPH	ZDBF2	1331	Q9HCK1
HLQSEVDQPQVSYKE	ZDBF2	1461	Q9HCK1
NTCPYVHNITRKVTN	POLR3K	26	Q9Y2Y1
LHPVNKNYQVQFVTL	GTF3C4	501	Q9UKN8
HAEKPKYQINNISTV	TJP1	1596	Q07157
VHLTNVAVQKTSPDY	TTLL9	251	Q3SXZ7
VHQLATYPDVNNSIK	VPS26A	151	O75436
ANAPVYQQNVLHTGK	WNK2	1296	Q9Y3S1
EASPNHLQTKAYVRQ	RAPGEFL1	626	Q9UHV5
YIDHKVPCTDSQVQV	ZZZ3	261	Q8IYH5
HNASENVTVIPNQVY	TCTN2	151	Q96GX1
TGQPDKIYVELHQNS	ZPBP2	36	Q6X784
NHLVYSQIPAAVKLT	UBR5	1806	O95071
NPVQVVLAKHVYEQV	VPS13D	1531	Q5THJ4
HPQTIAVVQTRAKYT	GLDC	226	P23378
PSQSLVVHDVEYLKN	KEL	331	P23276
TVQQPQILASHYQDV	MXRA5	1946	Q9NR99
VLQKNVVAYISLHSP	NAALADL2	516	Q58DX5
AQDVATNVNYKQPLH	NEB	1396	P20929