Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF728 ZNF92 ZNF451 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	5.25e-11	1412	66	23	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF728 ZNF92 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	6.87e-10	1459	66	22	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF729 ZNF502 KLF11 ZNF676 ZNF43 ZNF268 ZNF728 ZNF92 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	1.72e-09	1244	66	20	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF729 ZNF502 KLF11 ZNF676 ZNF43 ZNF268 ZNF728 ZNF92 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	2.50e-09	1271	66	20	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF729 ZNF43 ZNF268 ZNF727 ZNF91 ZNF99 PRDM15 ZNF445	5.00e-04	560	66	8	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF729 ZNF43 ZNF268 ZNF727 ZNF91 ZNF99 PRDM15 ZNF445	5.37e-04	566	66	8	GO:0001216
GeneOntologyBiologicalProcess	negative regulation of gene expression via chromosomal CpG island methylation	ZNF254 USP7 ZNF595 ZNF445	7.60e-07	23	65	4	GO:0044027
GeneOntologyBiologicalProcess	transposable element silencing	ZNF729 ZNF43 ZNF91 ZNF99	1.33e-05	46	65	4	GO:0010526
GeneOntologyBiologicalProcess	retrotransposition	ZNF729 ZNF43 ZNF91 ZNF99	1.57e-05	48	65	4	GO:0032197
GeneOntologyBiologicalProcess	transposition	ZNF729 ZNF43 ZNF91 ZNF99	1.85e-05	50	65	4	GO:0032196
MousePheno	decreased eosinophil cell number	ZNF729 ZNF43 ZNF727 ZNF91 ZNF99	9.71e-06	84	48	5	MP:0005012
Domain	zf-C2H2	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF451 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	1.03e-20	693	65	26	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF451 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	1.68e-19	775	65	26	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF451 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	1.79e-19	777	65	26	PS00028
Domain	KRAB	ZNF729 ZNF599 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF283 ZNF254 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 ZNF595 ZNF445	3.41e-19	358	65	20	PS50805
Domain	Znf_C2H2	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF451 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	4.30e-19	805	65	26	IPR007087
Domain	ZnF_C2H2	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF451 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	4.71e-19	808	65	26	SM00355
Domain	KRAB	ZNF729 ZNF599 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF283 ZNF254 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 ZNF595 ZNF445	6.20e-19	369	65	20	SM00349
Domain	KRAB	ZNF729 ZNF599 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF283 ZNF254 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 ZNF595 ZNF445	6.54e-19	370	65	20	IPR001909
Domain	-	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF445	1.86e-18	679	65	24	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF445	3.07e-18	694	65	24	IPR013087
Domain	Znf_C2H2-like	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF451 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF445	4.91e-18	796	65	25	IPR015880
Domain	KRAB	ZNF729 ZNF599 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF283 ZNF254 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 ZNF595 ZNF445	8.03e-18	358	65	19	PF01352
Domain	zf-C2H2_6	ZNF729 ZNF502 ZNF676 ZNF43 ZNF425 ZNF728 ZNF92 ZFP64 ZNF283 ZNF727 ZNF91 ZNF99 ZNF445	5.02e-11	314	65	13	PF13912
Domain	YD	NID2 TENM2	1.18e-04	5	65	2	IPR006530
Domain	Peptidase_M12B_N	ADAMTS1 ADAMTS18 ADAM22	3.36e-04	39	65	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS1 ADAMTS18 ADAM22	3.36e-04	39	65	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS1 ADAMTS18 ADAM22	3.63e-04	40	65	3	PS00427
Domain	Reprolysin	ADAMTS1 ADAMTS18 ADAM22	3.63e-04	40	65	3	PF01421
Domain	ADAM_MEPRO	ADAMTS1 ADAMTS18 ADAM22	3.63e-04	40	65	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS1 ADAMTS18 ADAM22	3.63e-04	40	65	3	PS50214
Domain	Peptidase_M12B	ADAMTS1 ADAMTS18 ADAM22	3.63e-04	40	65	3	IPR001590
Domain	Disintegrin_dom	ADAMTS1 ADAMTS18 ADAM22	3.90e-04	41	65	3	IPR001762
Domain	6-blade_b-propeller_TolB-like	NID2 DAW1 TENM2	5.49e-04	46	65	3	IPR011042
Domain	EGF_3	NELL1 NID2	7.70e-04	12	65	2	PF12947
Domain	EGF_dom	NELL1 NID2	7.70e-04	12	65	2	IPR024731
Domain	Quino_amine_DH_bsu	NID2 TENM2	2.63e-03	22	65	2	IPR011044
Domain	MetalloPept_cat_dom	ADAMTS1 ADAMTS18 ADAM22	2.83e-03	81	65	3	IPR024079
Domain	-	ADAMTS1 ADAMTS18 ADAM22	2.83e-03	81	65	3	3.40.390.10
Domain	ADAM_spacer1	ADAMTS1 ADAMTS18	2.88e-03	23	65	2	IPR010294
Domain	ADAM_spacer1	ADAMTS1 ADAMTS18	2.88e-03	23	65	2	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS1 ADAMTS18	3.13e-03	24	65	2	IPR013273
Domain	ACR	ADAMTS1 ADAM22	3.96e-03	27	65	2	SM00608
Domain	ADAM_Cys-rich	ADAMTS1 ADAM22	3.96e-03	27	65	2	IPR006586
Domain	VWC	NELL1 PXDN	4.25e-03	28	65	2	PF00093
Domain	ZINC_PROTEASE	ADAMTS1 ADAMTS18 ADAM22	4.84e-03	98	65	3	PS00142
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF729 ZNF599 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 PDPK1 ZNF92 ZNF254 USP7 ZNF727 ZNF470 ZNF221 ZNF235 CR1 ZNF679 ZNF99 ZNF595 CDC23 ZNF445	3.87e-09	1387	51	21	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF729 ZNF43 ZNF268 ZNF45 PDPK1 ZNF254 USP7 ZNF727 ZNF221 ZNF91 ZNF235 ZNF99 ZNF595 ZNF445	3.54e-07	768	51	14	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF729 ZNF43 ZNF268 ZNF45 PDPK1 ZNF254 USP7 ZNF727 ZNF221 ZNF91 ZNF235 ZNF99 ZNF595 ZNF445	1.03e-05	1022	51	14	MM15436
Pathway	KEGG_MEDICUS_REFERENCE_ALTERNATIVE_PATHWAY_OF_COMPLEMENT_CASCADE_C3B_BREAKDOWN	CD55 CR1	1.27e-04	5	51	2	M47875
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF729 ZNF43 ZNF254 ZNF727 ZNF91 ZNF679 ZNF99 ZNF595	4.50e-16	29	66	8	14563677
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF729 ZNF43 ZNF254 ZNF91 ZNF99 ZNF595	1.83e-13	15	66	6	15885501
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF729 ZNF43 ZNF727 ZNF91 ZNF99 ZNF445	4.85e-10	49	66	6	9630514
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF729 ZNF43 ZNF91 ZNF99	2.46e-09	10	66	4	18588511
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF729 ZNF43 ZNF91 ZNF99	3.86e-09	11	66	4	15469996
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF729 ZNF43 ZNF91 ZNF99	8.35e-09	13	66	4	19850934
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF43 ZNF92 ZNF91 ZNF99	2.12e-08	16	66	4	8467795
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF729 KLF11 ZNF43 ZNF451 ZFP64 ZNF254 ZNF91 ZNF235 ZNF679 ZNF99 ZNF595 ZNF445	3.56e-08	808	66	12	20412781
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF45 ZNF728 ZNF92 ZNF91 ZNF235 ZNF595 ZNF445	5.53e-08	181	66	7	37372979
Pubmed	The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.	ZNF43 ZNF92 ZNF91	3.63e-07	8	66	3	2023909
Pubmed	Decay-accelerating factor (DAF), complement receptor 1 (CR1), and factor H dissociate the complement AP C3 convertase (C3bBb) via sites on the type A domain of Bb.	CD55 CR1	3.55e-06	2	66	2	11694537
Pubmed	Activation of CD35 and CD55 in HIV associated normal and pre-eclamptic pregnant women.	CD55 CR1	3.55e-06	2	66	2	27521598
Pubmed	Analysis of homologous XRCC1-linked zinc-finger gene families in human and mouse: evidence for orthologous genes.	ZNF45 ZNF235	3.55e-06	2	66	2	9570955
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF283 ZNF221 ZNF235	7.27e-06	20	66	3	12743021
Pubmed	Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.	ZNF268 ZNF283 ZNF235	8.47e-06	21	66	3	7865130
Pubmed	Anaemia & expression levels of CD35, CD55 & CD59 on red blood cells in Plasmodium falciparum malaria patients from India.	CD55 CR1	1.06e-05	3	66	2	21727667
Pubmed	Differentially regulated ADAMTS1, 8, and 18 in gastric adenocarcinoma.	ADAMTS1 ADAMTS18	1.06e-05	3	66	2	28814085
Pubmed	Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen-1 and nidogen-2.	NID2 ADAMTS1	1.06e-05	3	66	2	23681936
Pubmed	Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor.	CD55 CR1	2.12e-05	4	66	2	12393518
Pubmed	Use of complement regulators, CD35, CD46, CD55, and CD59, on leukocytes as markers for diagnosis of viral and bacterial infections.	CD55 CR1	2.12e-05	4	66	2	23376460
Pubmed	DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity.	CD55 CR1	2.12e-05	4	66	2	16887189
Pubmed	Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack.	CD55 CR1	3.53e-05	5	66	2	17015743
Pubmed	Expression levels of CD47, CD35, CD55, and CD59 on red blood cells and signal-regulatory protein-alpha,beta on monocytes from patients with warm autoimmune hemolytic anemia.	CD55 CR1	3.53e-05	5	66	2	18954403
Pubmed	Deletion of Crry and DAF on murine platelets stimulates thrombopoiesis and increases factor H-dependent resistance of peripheral platelets to complement attack.	CD55 CR1	3.53e-05	5	66	2	23390291
Pubmed	A pair of mouse KRAB zinc finger proteins modulates multiple indicators of female reproduction.	ZNF254 ZNF595	3.53e-05	5	66	2	20042539
Pubmed	Crry, but not CD59 and DAF, is indispensable for murine erythrocyte protection in vivo from spontaneous complement attack.	CD55 CR1	3.53e-05	5	66	2	11986227
Pubmed	The KRAB zinc finger protein RSL1 modulates sex-biased gene expression in liver and adipose tissue to maintain metabolic homeostasis.	ZNF254 ZNF595	3.53e-05	5	66	2	24190968
Pubmed	Cys2His2 zinc finger protein family: classification, functions, and major members.	ZNF727 ZNF595	5.29e-05	6	66	2	22803940
Pubmed	Absence of CD59 exacerbates systemic autoimmunity in MRL/lpr mice.	CD55 CR1	5.29e-05	6	66	2	23109726
Pubmed	Symbionts exploit complex signaling to educate the immune system.	TLR1 CD209	5.29e-05	6	66	2	31811024
Pubmed	The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons.	ZNF254 ZNF595	5.29e-05	6	66	2	30846446
Pubmed	Complement-dependent T-cell lymphopenia caused by thymocyte deletion of the membrane complement regulator Crry.	CD55 CR1	5.29e-05	6	66	2	19136662
Pubmed	The KRAB zinc finger protein RSL1 regulates sex- and tissue-specific promoter methylation and dynamic hormone-responsive chromatin configuration.	ZNF254 ZNF595	7.40e-05	7	66	2	22801370
Pubmed	Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7.	ZNF45 ZNF235	7.40e-05	7	66	2	8617494
Pubmed	The regulation of the complement system: insights from genetically-engineered mice.	CD55 CR1	7.40e-05	7	66	2	12914820
Pubmed	Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation.	CD55 CR1	7.40e-05	7	66	2	28057640
Pubmed	Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites.	REG1B CD209	9.86e-05	8	66	2	34375000
Pubmed	Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway.	CD55 CR1	9.86e-05	8	66	2	14670299
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ATRX ZNF92 ZNF451 USP7 AASDH ZMYM3 CDC23	1.25e-04	588	66	7	38580884
Pubmed	Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes.	ZNF254 ZNF595	1.27e-04	9	66	2	10360839
Pubmed	Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1.	ZNF268 ZNF91	1.27e-04	9	66	2	23665872
Pubmed	Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.	CD55 CR1	1.27e-04	9	66	2	18947875
Pubmed	Expression of signaling components in embryonic eyelid epithelium.	ADAMTS1 DKK2	1.58e-04	10	66	2	24498290
Pubmed	Circulating AIM prevents hepatocellular carcinoma through complement activation.	CD55 CR1	1.58e-04	10	66	2	25284781
Pubmed	Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis.	CD55 CR1	1.93e-04	11	66	2	23204401
Pubmed	Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.	CD55 CR1	2.31e-04	12	66	2	18524992
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS1 ADAMTS18	2.31e-04	12	66	2	25770910
Pubmed	ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.	ADAMTS1 ADAMTS18	4.18e-04	16	66	2	30579834
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EPS15 PXDN ATRX ZFP64 TTC12 ZFHX2 ANKMY1 EIPR1 PRDM15 ZNF595	4.76e-04	1489	66	10	28611215
Pubmed	Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.	TLR1 CR1	5.94e-04	19	66	2	20459687
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	NID2 PXDN ADAMTS1	5.97e-04	86	66	3	28327460
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF254 ZNF595	6.59e-04	20	66	2	2542606
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF254 ZNF595	6.59e-04	20	66	2	7479878
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ATRX ZNF254 CD55 ADAMTS18 FERMT2 TAPBP ZNF595 ZNF445	1.01e-03	1084	66	8	11544199
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ATRX ZNF451 USP7 PRDM15 ZMYM3 WDR43	1.04e-03	608	66	6	36089195
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	EPS15 ELP2 CDC23	1.10e-03	106	66	3	31024071
Pubmed	Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.	ZNF254 PRDM15	1.30e-03	28	66	2	23006423
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	USP7 ZNF235 CDC23	1.42e-03	116	66	3	21549307
Pubmed	Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.	CD55 CR1	1.59e-03	31	66	2	19344414
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF43 ZNF45	1.59e-03	31	66	2	2288909
Pubmed	Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function.	EPS15 USP7	1.59e-03	31	66	2	36114200
Pubmed	A census of human transcription factors: function, expression and evolution.	KLF11 ZNF43 ZNF268 ZNF451 ZNF254 ZFHX2 ZNF91	1.65e-03	908	66	7	19274049
Pubmed	Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.	CD55 CR1	1.70e-03	32	66	2	18842294
Pubmed	Maternal diabetes alters transcriptional programs in the developing embryo.	SEMA3A ATRX	1.70e-03	32	66	2	19538749
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF729 ZNF676 ZNF43 ZNF728 ZNF254 ZNF91 ZNF99	5.38e-10	122	66	7	chr19p12
Cytoband	19p12	ZNF729 ZNF676 ZNF728 ZNF254 ZNF91 ZNF99	3.96e-09	90	66	6	19p12
Cytoband	2p25	KLF11 PXDN KCNF1	2.28e-06	18	66	3	2p25
Cytoband	Ensembl 112 genes in cytogenetic band chr2p25	KLF11 PXDN KCNF1 EIPR1	3.52e-05	127	66	4	chr2p25
Cytoband	7q11.21	ZNF92 ZNF727 ZNF679	2.40e-04	83	66	3	7q11.21
Cytoband	14q22.1	NID2 FERMT2	8.63e-04	30	66	2	14q22.1
Cytoband	19q13.2	ZNF45 ZNF221 ZNF235	1.74e-03	164	66	3	19q13.2
Cytoband	Xq13.1	NALF2 ZMYM3	2.20e-03	48	66	2	Xq13.1
Cytoband	1q32	CD55 CR1	2.29e-03	49	66	2	1q32
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	ZNF92 ZNF727 ZNF679	7.08e-03	271	66	3	chr7q11
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF599 ZNF45 ZNF283 ZNF470 ZNF221 ZNF235	7.32e-03	1192	66	6	chr19q13
Cytoband	Ensembl 112 genes in cytogenetic band chr14q22	NID2 FERMT2	8.17e-03	94	66	2	chr14q22
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF729 ZNF502 ZNF599 KLF11 ZNF676 ZNF43 ZNF268 ZNF425 ZNF45 ZNF728 ZNF92 ZNF451 ZFP64 ZNF283 ZNF254 ZFHX2 ZNF727 ZNF470 ZNF221 ZNF91 ZNF235 ZNF679 ZNF99 PRDM15 ZNF595 ZNF445	5.17e-22	718	56	26	28
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS1 ADAMTS18	1.56e-03	19	56	2	50
Coexpression	TERAO_AOX4_TARGETS_SKIN_DN	ZNF729 ZNF43 MRNIP ZNF91 ZNF99	8.15e-09	28	66	5	MM925
Coexpression	MIKKELSEN_NPC_ICP_WITH_H3K4ME3	ZNF729 SEMA3A ZNF43 ZNF254 ZNF727 ZNF91 ZNF235 ZNF99 ZNF595	4.18e-06	497	66	9	MM863
Coexpression	COATES_MACROPHAGE_M1_VS_M2_UP	ZNF729 ZNF43 ZNF727 ZNF91 ZNF99	5.98e-06	102	66	5	MM749
Coexpression	MIKKELSEN_ES_ICP_WITH_H3K4ME3	ZNF729 SEMA3A ZNF43 TTC12 ZNF254 ZNF727 ZNF91 ZNF235 ZNF99 ZNF595	3.21e-05	807	66	10	MM855
Coexpression	GAVIN_FOXP3_TARGETS_CLUSTER_P2	EPS15 CD7 DAW1 ZNF91	5.27e-05	81	66	4	M1732
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Papillary_Adenocarcinoma-4\|TCGA-Lung / Sample_Type by Project: Shred V9	ZNF729 ZNF676 ZNF728 REG1B ZNF99	6.62e-07	111	66	5	bcecf3498a5fbd52dcdf56e68858b2da39d96ba9
ToppCell	BAL-Control-cDC_8\|Control / Compartment, Disease Groups and Clusters	STARD13 ZNF43 ZNF283 ZNF727 CR1	7.30e-06	181	66	5	f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA3A NELL1 PXDN FERMT2 DKK2	1.16e-05	199	66	5	3d8c76e3d05acf72a35ca755b51579fc3ae63562
ToppCell	VE-CD8-proli_CD4\|VE / Condition, Cell_class and T cell subcluster	ZNF425 ZFP64 TTC12 FERMT2	1.55e-05	101	66	4	5293f15b5ed340e6d0282b56de13752eabeef8dd
Disease	smoking status measurement, triglyceride measurement	ZNF729 ZNF676	6.69e-05	6	63	2	EFO_0004530, EFO_0006527
Disease	aspergillosis (is_implicated_in)	TLR1 CD209	1.25e-04	8	63	2	DOID:13564 (is_implicated_in)
Disease	Alzheimer disease, polygenic risk score	NELL1 PXDN ZNF45 ZNF92 CD55 CR1	1.56e-03	586	63	6	EFO_0030082, MONDO_0004975
Disease	tuberculosis (is_implicated_in)	TLR1 CD209	1.64e-03	28	63	2	DOID:399 (is_implicated_in)
Disease	Mental Retardation, X-Linked	ATRX ZMYM3	1.76e-03	29	63	2	C1136249
Disease	Drug Use Disorders	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C0013222
Disease	Drug Dependence	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C1510472
Disease	Drug habituation	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C0013170
Disease	Substance Dependence	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C0038580
Disease	Substance Use Disorders	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C0038586
Disease	Substance-Related Disorders	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C0236969
Disease	Drug abuse	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C0013146
Disease	Organic Mental Disorders, Substance-Induced	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C0029231
Disease	Prescription Drug Abuse	EIPR1 DNAH8 TENM2	1.93e-03	115	63	3	C4316881
Disease	Substance abuse problem	EIPR1 DNAH8 TENM2	1.98e-03	116	63	3	C0740858
Disease	Alzheimer disease, family history of Alzheimer’s disease	ADAMTS1 CR1 FERMT2	2.13e-03	119	63	3	EFO_0009268, MONDO_0004975
Disease	age of onset of Alzheimer disease	CR1 FERMT2	2.27e-03	33	63	2	OBA_2001000
Disease	late-onset Alzheimers disease	SEMA3A ADAMTS1 CR1 FERMT2	3.54e-03	292	63	4	EFO_1001870
Disease	macrophage migration inhibitory factor measurement	ZNF43 USP7	3.83e-03	43	63	2	EFO_0008221
Disease	PR interval	SEMA3A NELL1 EPS15 FERMT2 ADAM22	4.12e-03	495	63	5	EFO_0004462

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSWKGKECLLKLCDT	AMER3	486	Q8N944
FKCKLWDEASTCAQK	CDC23	521	Q9UJX2
KKLCSWRDKNSAACV	CD7	206	P09564
KLASGECKCEDTWSG	ADAM22	386	Q9P0K1
KKCVWKSKCGGTVFS	AASDH	886	Q4L235
LAKFWICKKSAASCS	CD209	371	Q9NNX6
CDCAKGLSCKVWKDA	DKK2	231	Q9UBU2
GLSCKVWKDATYSSK	DKK2	236	Q9UBU2
CKWQFGAKAKLCSLG	ADAMTS18	521	Q8TE60
EWSSCSKTCGKGYKK	ADAMTS1	916	Q9UHI8
SVKWTCKACGEKQSF	MRNIP	26	Q6NTE8
RLFDEGTISKWKDCC	MB21D2	151	Q8IYB1
WSTAVEFCKKKSCPN	CD55	151	P08174
EKSCCKPSWGESLKL	DNAH8	3206	Q96JB1
DKTCKLWSVETGKCY	DAW1	156	Q8N136
MDKTCKLWDATNGKC	DAW1	281	Q8N136
TKCCDVQWVSCEAKK	NALF2	356	O75949
SCGDDCKVKFWDTRN	EIPR1	246	Q53HC9
ECKNWNTKATCECKS	NELL1	406	Q92832
KKILDDWGETCKGCA	MANF	141	P55145
KLLCWADAGTKKLEC	NID2	1286	Q14112
MWDCCCESVKKTKKS	ATRX	1571	P46100
VWSSPKDVCKRKSCK	CR1	541	P17927
VWSSPKDVCKRKSCK	CR1	991	P17927
LTCSKYCKTKAWTEF	ANKMY1	901	Q9P2S6
CSWDGCDKKFARSDE	KLF11	426	O14901
WSLCDTKDCGKLSKD	EPS15	266	P42566
AIRKLCWKNCSGKTE	ELP2	781	Q6IA86
WCTFKDTSISCYKSK	FERMT2	396	Q96AC1
YCASLTSCSGFKKWK	REG1B	136	P48304
TSCSGFKKWKDESCE	REG1B	141	P48304
KIASAEGWKKTFATC	OR10J6P	226	Q8NGY7
AKEKFKGWVTCSSTD	STARD13	921	Q9Y3M8
TVGKQWTCSVCDKKY	PRDM15	1191	P57071
EKSACKSSDLWALGC	PDPK1	256	O15530
KPSKYCSWKCAALSA	TENM2	366	Q9NT68
DECKWAGKDILKECA	SEMA3A	101	Q14563
SYDEKKGDCSWTKSL	TLR1	411	Q15399
CEECGKTFKWFPDLT	ZNF727	426	A8MUV8
LDKGKLWFRCSLCSA	ZNF451	746	Q9Y4E5
EECGKAFKWSSKLTV	ZNF99	736	A8MXY4
KLYKCEECGKAFTWS	ZNF595	366	Q8IYB9
KCEECGKAFIWSASL	ZNF595	481	Q8IYB9
KCEKCGKAFSWSSAF	ZNF92	426	Q03936
CTECGKGFSKKWALV	ZNF599	201	Q96NL3
KCEECGKAFSWSSIL	ZNF676	506	Q8N7Q3
KCTECGKAFCWKSQL	ZNF268	921	Q14587
KEPKTKSSWQCKVCS	ZFHX2	561	Q9C0A1
GWAAVYLSTCKDSKK	TAPBP	431	O15533
KCEECDKAFKWSSSL	ZNF679	381	Q8IYX0
NTKWKKDACTICECK	PXDN	1426	Q92626
YKCEECGKTFKWSST	ZNF728	396	P0DKX0
KCEECGKAFKWSSNL	ZNF728	481	P0DKX0
ECSTLGKNWKCEDLF	ZNF470	131	Q6ECI4
EECGKAFKWSSKLTE	ZNF43	401	P17038
KCEECGKAFKWSSKL	ZNF43	511	P17038
KCEECGKAFKWSSTL	ZNF43	651	P17038
KCKECEKTFHWSSTL	ZNF91	211	Q05481
PFKCKECGKAFIWSS	ZNF91	461	Q05481
KCKECGKAFIWSSTL	ZNF91	771	Q05481
FKCSKCGKTFRWSSN	ZNF445	1006	P59923
KECGKSFGWASCLLK	ZNF221	481	Q9UK13
QKKSWKCNECGKTFT	ZNF502	151	Q8TBZ5
VDCEWALKCDEKCTK	TTC12	161	Q9H892
MWSKKCSGVACLVKD	WASL	56	O00401
CPECDKSFSWKASMK	ZNF425	556	Q6IV72
KWCKFDDDVVSRCTK	USP7	476	Q93009
KCEECGKEFSWSAGL	ZNF235	656	Q14590
CWLCSAKFKISSDLK	ZFP64	416	Q9NTW7
KCEECGKGFSWSSSL	ZNF45	641	Q02386
KTCTFCKKEIWNTKD	ZMYM3	351	Q14202
KCKECGKTFNWSSTL	ZNF254	211	O75437
QTCKVKCKWKGDNSS	WDR43	156	Q15061
KCKWKGDNSSVSSLC	WDR43	161	Q15061
CEECGKAFKWSSKLT	ZNF729	546	A6NN14
KCEECGKAFKWLSKL	ZNF729	881	A6NN14
EECGKAFKWSSKLTE	ZNF729	1051	A6NN14
CKECGKAFSWGSSLV	ZNF283	461	Q8N7M2
FKCKECGKAFSWGSS	ZNF283	571	Q8N7M2
WKVDLKFLDDCCKSH	KCNF1	116	Q9H3M0