Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

GLB1L NRP2 MFGE8 ANAPC10 CNTNAP2

6.76e-057310952.60.120.260
DomainGalactose-bd-like

GLB1L NRP2 MFGE8 ANAPC10 CNTNAP2

2.24e-04941095IPR008979
DomainFA58C

NRP2 MFGE8 CNTNAP2

2.38e-04211093SM00231
DomainFA58C_3

NRP2 MFGE8 CNTNAP2

2.38e-04211093PS50022
DomainFA58C_1

NRP2 MFGE8 CNTNAP2

2.38e-04211093PS01285
DomainFA58C_2

NRP2 MFGE8 CNTNAP2

2.38e-04211093PS01286
DomainQuinoprotein_ADH-like_supfam

GEMIN5 OLFM1 WDR1 WDR17

2.58e-04531094IPR011047
DomainPHR

BTBD1 BTBD2

3.34e-0451092IPR012983
DomainPHR

BTBD1 BTBD2

3.34e-0451092PF08005
DomainF5_F8_type_C

NRP2 MFGE8 CNTNAP2

3.58e-04241093PF00754
DomainFA58C

NRP2 MFGE8 CNTNAP2

3.58e-04241093IPR000421
Domainfn3

CHL1 NPHS1 FNDC3B DSCAM COL20A1 FNDC4

3.76e-041621096PF00041
DomainWD40_repeat_CS

NUP43 GEMIN5 AMBRA1 WDR1 WDR17 BRWD1

4.02e-041641096IPR019775
DomainSTAT_TF_DNA-bd_sub

STAT5A STAT5B

6.95e-0471092IPR012345
DomainSTAT

STAT5A STAT5B

6.95e-0471092IPR001217
DomainSTAT_int

STAT5A STAT5B

6.95e-0471092SM00964
DomainSTAT_TF_DNA-bd

STAT5A STAT5B

6.95e-0471092IPR013801
DomainSTAT_bind

STAT5A STAT5B

6.95e-0471092PF02864
DomainSTAT_int

STAT5A STAT5B

6.95e-0471092PF02865
Domain-

STAT5A STAT5B

6.95e-04710921.10.532.10
DomainSTAT_alpha

STAT5A STAT5B

6.95e-0471092PF01017
Domain-

STAT5A STAT5B

6.95e-04710921.20.1050.20
DomainSTAT_TF_prot_interaction

STAT5A STAT5B

6.95e-0471092IPR013799
DomainSTAT_TF_coiled-coil

STAT5A STAT5B

6.95e-0471092IPR015988
Domain-

STAT5A STAT5B

6.95e-04710922.60.40.630
DomainFN3

CHL1 NPHS1 FNDC3B DSCAM COL20A1 FNDC4

7.58e-041851096SM00060
DomainWD40

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

8.15e-042591097PF00400
DomainFIBRINOGEN_C_1

ITLN1 FCN3 CNTNAP2

8.48e-04321093PS00514
DomainFibrinogen_a/b/g_C_dom

ITLN1 FCN3 CNTNAP2

8.48e-04321093IPR002181
DomainFIBRINOGEN_C_2

ITLN1 FCN3 CNTNAP2

8.48e-04321093PS51406
DomainSTAT_TF_alpha

STAT5A STAT5B

9.24e-0481092IPR013800
DomainBcl2_BH3_motif_CS

BCL2L1 BID

9.24e-0481092IPR020728
DomainWD40

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

9.94e-042681097SM00320
DomainWD40_repeat

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

1.08e-032721097IPR001680
Domain-

GLB1L LCT SLC3A2

1.10e-033510933.20.20.80
DomainFN3

CHL1 NPHS1 FNDC3B DSCAM COL20A1 FNDC4

1.11e-031991096PS50853
DomainWD_REPEATS_1

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

1.23e-032781097PS00678
DomainWD_REPEATS_2

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

1.25e-032791097PS50082
DomainWD_REPEATS_REGION

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

1.25e-032791097PS50294
DomainGlyco_hydro_catalytic_dom

GLB1L LCT SLC3A2

1.41e-03381093IPR013781
DomainFN3_dom

CHL1 NPHS1 FNDC3B DSCAM COL20A1 FNDC4

1.42e-032091096IPR003961
DomainArrestin-like_N

ARRDC1 ARRDC5

1.47e-03101092IPR011021
DomainArrestin_C-like

ARRDC1 ARRDC5

1.47e-03101092IPR011022
DomainArrestin_C

ARRDC1 ARRDC5

1.47e-03101092SM01017
DomainArrestin_C

ARRDC1 ARRDC5

1.47e-03101092PF02752
DomainArrestin_N

ARRDC1 ARRDC5

1.47e-03101092PF00339
DomainWD40_repeat_dom

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

1.79e-032971097IPR017986
DomainN2O_reductase_N

WDR1 WDR17

3.37e-03151092IPR011045
Domain-

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

3.39e-0333310972.130.10.10
DomainWD40/YVTN_repeat-like_dom

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

3.51e-033351097IPR015943
DomainGlycoside_hydrolase_SF

GLB1L LCT SLC3A2

3.66e-03531093IPR017853
Domain-

SYNRG EFCAB6 HRNR STAT5A STAT5B CRNN

4.29e-0326110961.10.238.10
DomainBH3

BCL2L1 BID

4.33e-03171092PS01259
DomainLaminin_G

COL20A1 TSPEAR CNTNAP2

4.73e-03581093IPR001791
PathwayREACTOME_STAT5_ACTIVATION_DOWNSTREAM_OF_FLT3_ITD_MUTANTS

BCL2L1 STAT5A STAT5B

1.90e-0510783M41731
PathwayREACTOME_INTERLEUKIN_7_SIGNALING

STAT5A STAT5B BRWD1

7.07e-0515783MM14536
PathwayREACTOME_SIGNALING_BY_FLT3_ITD_AND_TKD_MUTANTS

BCL2L1 STAT5A STAT5B

8.66e-0516783M41733
PathwayWP_NEPHROTIC_SYNDROME

NPHS1 ITGA3 CUBN WDR73

1.09e-0445784M39864
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

2.99e-045782M48987
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

2.99e-045782M48986
PathwayKEGG_MEDICUS_REFERENCE_PRL_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

2.99e-045782M49006
PathwayWP_IL7_SIGNALING

BCL2L1 STAT5A STAT5B

3.43e-0425783M39499
PathwayPID_IL3_PATHWAY

BCL2L1 STAT5A STAT5B

3.87e-0426783M182
PathwayREACTOME_INTERLEUKIN_9_SIGNALING

STAT5A STAT5B

4.47e-046782MM15581
PathwayREACTOME_INTERLEUKIN_21_SIGNALING

STAT5A STAT5B

4.47e-046782MM15621
PathwayREACTOME_FLT3_SIGNALING_IN_DISEASE

BCL2L1 STAT5A STAT5B

4.83e-0428783M41724
PathwayPID_IL2_STAT5_PATHWAY

BCL2L1 STAT5A STAT5B

5.94e-0430783M234
PathwayREACTOME_STAT5_ACTIVATION

STAT5A STAT5B

6.23e-047782M27953
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

6.23e-047782M47581
PathwayKEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

6.23e-047782M47646
PathwayREACTOME_BH3_ONLY_PROTEINS_ASSOCIATE_WITH_AND_INACTIVATE_ANTI_APOPTOTIC_BCL_2_MEMBERS

BCL2L1 BID

6.23e-047782MM14483
PathwayKEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY

STAT5A STAT5B

6.23e-047782M47430
PathwayREACTOME_ERYTHROPOIETIN_ACTIVATES_STAT5

STAT5A STAT5B

6.23e-047782M27907
PathwayPID_EPO_PATHWAY

BCL2L1 STAT5A STAT5B

7.89e-0433783M233
PathwayREACTOME_INTERLEUKIN_7_SIGNALING

STAT5A STAT5B BRWD1

1.02e-0336783M542
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

RANBP2 DUSP6 FRS2 BCL2L1 STAT5A STAT5B KDM7A FAM131B SMAD2

1.02e-03464789M27547
PathwayREACTOME_BH3_ONLY_PROTEINS_ASSOCIATE_WITH_AND_INACTIVATE_ANTI_APOPTOTIC_BCL_2_MEMBERS

BCL2L1 BID

1.06e-039782M26904
PathwayREACTOME_INTERLEUKIN_9_SIGNALING

STAT5A STAT5B

1.06e-039782M27861
PathwayBIOCARTA_IL22BP_PATHWAY

STAT5A STAT5B

1.06e-039782MM1419
PathwayBIOCARTA_IL22BP_PATHWAY

STAT5A STAT5B

1.06e-039782M8066
PathwayREACTOME_SIGNALING_BY_FGFR1_IN_DISEASE

FRS2 STAT5A STAT5B

1.20e-0338783M27536
PathwayREACTOME_INTERLEUKIN_21_SIGNALING

STAT5A STAT5B

1.32e-0310782M27898
PathwayREACTOME_INTERLEUKIN_2_SIGNALING

STAT5A STAT5B

1.32e-0310782MM15618
Pubmed

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

SEMG1 GEMIN5 HRNR SLC3A2 TMPO MTDH

2.47e-0854114625631074
Pubmed

Association study of IL-17RC, CHL1, DSCAM and CNTNAP2 genes polymorphisms with adolescent idiopathic scoliosis susceptibility in a Chinese Han population.

CHL1 DSCAM CNTNAP2

1.37e-074114322744455
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

EFCAB6 DSCAM FRS2 SPECC1L HRNR DNAH7 ARL5A SLC3A2 ARL5B TMPO DCLRE1A EBNA1BP2 MTDH AGAP1

2.73e-077771141435844135
Pubmed

Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter.

BCL2L1 STAT5A STAT5B

3.41e-075114322729867
Pubmed

Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation.

BCL2L1 STAT5A STAT5B

6.81e-076114310652277
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DSCAM TRPS1 NUP43 BTBD1 BTBD2 MED13L STAT5B MFGE8 OTOF ADAMTS9 LRP4 OLFM1 WDR17 GPRASP2 SMAD2 AGAP1 BRWD1

1.01e-0612851141735914814
Pubmed

Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways.

BCL2L1 STAT5A STAT5B

1.19e-067114322086418
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

NPHS1 ARRDC1 ITLN1 ACP1 TM7SF3 ITGA3 CUBN SLC3A2 MFGE8 SLC46A3 CRNN GATD1 WDR1 TBC1D21 PACSIN2

1.22e-0610161141519056867
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

SEMG1 RANBP2 ACP1 GEMIN5 HRNR SLC3A2 MEMO1 ATAD3A TMPO EBNA1BP2 WDR1 MTDH

1.39e-066411141236057605
Pubmed

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.

BCL2L1 STAT5A STAT5B

2.84e-069114319946273
Pubmed

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

BCL2L1 STAT5A STAT5B

4.05e-0610114318694996
Pubmed

Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.

STAT5A STAT5B

1.07e-052114223151802
Pubmed

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

STAT5A STAT5B

1.07e-052114226999798
Pubmed

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.

STAT5A STAT5B

1.07e-052114231443474
Pubmed

Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.

STAT5A STAT5B

1.07e-052114212377952
Pubmed

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.

STAT5A STAT5B

1.07e-052114221127177
Pubmed

The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.

STAT5A STAT5B

1.07e-052114216289657
Pubmed

Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.

STAT5A STAT5B

1.07e-052114225552366
Pubmed

Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.

STAT5A STAT5B

1.07e-052114225470773
Pubmed

Constitutively active Stat5A and Stat5B promote adipogenesis.

STAT5A STAT5B

1.07e-052114221431790
Pubmed

Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.

STAT5A STAT5B

1.07e-052114228500076
Pubmed

STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.

STAT5A STAT5B

1.07e-052114221826656
Pubmed

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

STAT5A STAT5B

1.07e-05211427720707
Pubmed

Mapping the interaction of pro-apoptotic tBID with pro-survival BCL-XL.

BCL2L1 BID

1.07e-052114219670908
Pubmed

STAT5A and STAT5B have opposite correlations with drug response gene expression.

STAT5A STAT5B

1.07e-052114227264955
Pubmed

Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.

STAT5A STAT5B

1.07e-052114222159083
Pubmed

STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.

STAT5A STAT5B

1.07e-052114220008792
Pubmed

STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.

STAT5A STAT5B

1.07e-052114233199496
Pubmed

The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.

STAT5A STAT5B

1.07e-052114216502315
Pubmed

Stat5: an essential regulator of mast cell biology.

STAT5A STAT5B

1.07e-052114212217382
Pubmed

Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.

STAT5A STAT5B

1.07e-052114231599926
Pubmed

DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.

STAT5A STAT5B

1.07e-052114210594041
Pubmed

Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.

STAT5A STAT5B

1.07e-052114221036145
Pubmed

Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.

STAT5A STAT5B

1.07e-052114210486277
Pubmed

The C(H)1 and transmembrane domains of mu in the context of a gamma2b transgene do not suffice to promote B cell maturation.

BCL2L1 IGHM

1.07e-052114210508184
Pubmed

Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.

STAT5A STAT5B

1.07e-052114216840779
Pubmed

The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.

STAT5A STAT5B

1.07e-052114215128421
Pubmed

STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.

STAT5A STAT5B

1.07e-052114230377054
Pubmed

Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.

STAT5A STAT5B

1.07e-052114223565285
Pubmed

Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.

STAT5A STAT5B

1.07e-052114232790723
Pubmed

In vivo identification of novel STAT5 target genes.

STAT5A STAT5B

1.07e-052114218492722
Pubmed

Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.

STAT5A STAT5B

1.07e-052114210066807
Pubmed

Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.

STAT5A STAT5B

1.07e-052114210835485
Pubmed

Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.

STAT5A STAT5B

1.07e-052114235464049
Pubmed

Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.

STAT5A STAT5B

1.07e-052114218286195
Pubmed

Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.

STAT5A STAT5B

1.07e-052114223773921
Pubmed

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.

STAT5A STAT5B

1.07e-05211428631883
Pubmed

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.

STAT5A STAT5B

1.07e-052114211030348
Pubmed

Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.

STAT5A STAT5B

1.07e-052114224878107
Pubmed

Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells.

BCL2L1 STAT5A

1.07e-052114216684963
Pubmed

Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.

STAT5A STAT5B

1.07e-052114212847485
Pubmed

Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.

STAT5A STAT5B

1.07e-052114212835478
Pubmed

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.

STAT5A STAT5B

1.07e-05211427568026
Pubmed

Identification of STAT5A and STAT5B target genes in human T cells.

STAT5A STAT5B

1.07e-052114224497979
Pubmed

Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.

STAT5A STAT5B

1.07e-052114217536022
Pubmed

STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.

STAT5A STAT5B

1.07e-052114217382296
Pubmed

STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.

STAT5A STAT5B

1.07e-052114217911616
Pubmed

STAT5 signaling in sexually dimorphic gene expression and growth patterns.

STAT5A STAT5B

1.07e-052114210486314
Pubmed

The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.

STAT5A STAT5B

1.07e-052114217599554
Pubmed

MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.

STAT5A STAT5B

1.07e-052114224497923
Pubmed

Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.

STAT5A STAT5B

1.07e-052114224335105
Pubmed

Brain STAT5 signaling modulates learning and memory formation.

STAT5A STAT5B

1.07e-052114229460051
Pubmed

STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.

STAT5A STAT5B

1.07e-052114228606561
Pubmed

Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.

STAT5A STAT5B

1.07e-052114212393407
Pubmed

The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.

STAT5A STAT5B

1.07e-052114212039059
Pubmed

Differential changes in responses of hypothalamic and brainstem neuronal populations to prolactin during lactation in the mouse.

STAT5A STAT5B

1.07e-052114221178171
Pubmed

Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.

STAT5A STAT5B

1.07e-052114220233708
Pubmed

Involvement of the STAT5 signaling pathway in the regulation of mouse preimplantation development.

STAT5A STAT5B

1.07e-052114216775227
Pubmed

STAT5 isoforms: controversies and clarifications.

STAT5A STAT5B

1.07e-052114217447893
Pubmed

Membrane promotes tBID interaction with BCL(XL).

BCL2L1 BID

1.07e-052114219820711
Pubmed

Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence.

STAT5A STAT5B

1.07e-052114216115927
Pubmed

Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.

STAT5A STAT5B

1.07e-052114223275557
Pubmed

Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation.

STAT5A STAT5B

1.07e-052114211867689
Pubmed

Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.

STAT5A STAT5B

1.07e-052114215980098
Pubmed

Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.

STAT5A STAT5B

1.07e-052114215340066
Pubmed

STAT5A/B gene locus undergoes amplification during human prostate cancer progression.

STAT5A STAT5B

1.07e-052114223660011
Pubmed

Role of Stat5 in type I interferon-signaling and transcriptional regulation.

STAT5A STAT5B

1.07e-052114212901872
Pubmed

Identification and characterization of BTBD1, a novel BTB domain containing gene on human chromosome 15q24.

BTBD1 BTBD2

1.07e-052114211179693
Pubmed

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.

STAT5A STAT5B

1.07e-052114228074064
Pubmed

STAT5b: A master regulator of key biological pathways.

STAT5A STAT5B

1.07e-052114236755813
Pubmed

Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling.

STAT5A STAT5B

1.07e-052114225333863
Pubmed

A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance.

STAT5A STAT5B

1.07e-052114212421978
Pubmed

A single amino acid in the DNA binding regions of STAT5A and STAT5B confers distinct DNA binding specificities.

STAT5A STAT5B

1.07e-05211429852045
Pubmed

Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior.

STAT5A STAT5B

1.07e-052114219966185
Pubmed

Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer.

STAT5A STAT5B

1.07e-052114221704724
Pubmed

Suppression of mitochondrial function by oxidatively truncated phospholipids is reversible, aided by bid, and suppressed by Bcl-XL.

BCL2L1 BID

1.07e-052114219654426
Pubmed

Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.

STAT5A STAT5B

1.07e-052114238618957
Pubmed

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

BCL2L1 BID

1.07e-052114215353804
Pubmed

Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.

STAT5A STAT5B

1.07e-05211428732682
Pubmed

How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5.

STAT5A STAT5B

1.07e-052114226717567
Pubmed

The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5.

STAT5A STAT5B

1.07e-052114232281944
Pubmed

Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice.

STAT5A STAT5B

1.07e-052114234818373
Pubmed

CD82/KAI1 Maintains the Dormancy of Long-Term Hematopoietic Stem Cells through Interaction with DARC-Expressing Macrophages.

CD82 ACKR1

1.07e-052114226996598
Pubmed

Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting.

STAT5A STAT5B

1.07e-052114223465551
Pubmed

STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells.

STAT5A STAT5B

1.07e-052114211756158
Pubmed

Lack of Association of Polymorphism Located Upstream of ABCA1 (rs2472493), in FNDC3B (rs7636836), and Near ANKRD55-MAP3K1 Genes (rs61275591) in Primary Open-Angle Glaucoma Patients of Saudi Origin.

FNDC3B ABCA1

1.07e-052114236980976
Pubmed

IL-3 Differentially Regulates Membrane and Soluble RANKL in Osteoblasts through Metalloproteases and the JAK2/STAT5 Pathway and Improves the RANKL/OPG Ratio in Adult Mice.

STAT5A STAT5B

1.07e-052114229203513
Pubmed

LMW-PTP associates and dephosphorylates STAT5 interacting with its C-terminal domain.

ACP1 STAT5A

1.07e-052114214637146
Pubmed

Prognostic significance of signal transducer and activator of transcription 5 and 5b expression in Epstein-Barr virus-positive patients with chronic lymphocytic leukemia.

STAT5A STAT5B

1.07e-052114227367207
Pubmed

Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation.

STAT5A STAT5B

1.07e-052114216493008
GeneFamilyWD repeat domain containing|DDB1 and CUL4 associated factors

AMBRA1 DCAF16 BRWD1

5.79e-0518773498
GeneFamilyFibronectin type III domain containing

CHL1 NPHS1 FNDC3B DSCAM COL20A1 FNDC4

6.17e-05160776555
GeneFamilyWD repeat domain containing

NUP43 GEMIN5 AMBRA1 WDR73 WDR1 WDR17 BRWD1

1.26e-04262777362
GeneFamilyAlpha arrestins

ARRDC1 ARRDC5

2.66e-0467721311
GeneFamilyEF-hand domain containing|S100 fused type protein family

HRNR CRNN

3.71e-0477721350
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CHL1 FNDC3B DENND2A ABCA1 CD82 MRC2 OLFM1

7.74e-0719911378b86c69aaf60feff53aa782559cfece7342a23de
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte|GW23 / Sample Type, Dataset, Time_group, and Cell type.

COL20A1 DUSP6 TRPS1 MFGE8 CD82 MRC2 LRP4

8.01e-0720011374fe3b2d80c567c18621bff3341f9a73578c81621
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

MAP1A TRPS1 ADAMTS9 MRC2 SORCS2 FAM131B

6.27e-061781136ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHL1 DLGAP2 TRPS1 NRP2 CD82 CNTNAP2

8.06e-0618611367def03dd856b765bd3f493288641981c4f7fd26e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 FNDC3B DENND2A PPP1R9A ITGA3 DNAH7

9.95e-061931136f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 FNDC3B DENND2A PPP1R9A ITGA3 DNAH7

9.95e-06193113642df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 ABCA1 ITGA3 LENG8 ADAMTS9 MRC2

1.09e-051961136b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

FNDC3B PPP1R9A TRPS1 AMBRA1 MED13L AGAP1

1.18e-05199113694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellTransplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

ITLN1 FNDC4 MED13L KHDRBS3 ADAMTS9 ACKR1

1.18e-0519911366cfefd81e8a1a883fb4279ac4ab0b298ed2a0817
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial|GW23 / Sample Type, Dataset, Time_group, and Cell type.

COL20A1 DUSP6 TRPS1 MFGE8 CD82 MRC2

1.22e-05200113670c2e577efb6b6fe8f9d970d7ecc470788efb85b
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DENND2A NUP43 GEMIN5 AMBRA1 STAT5A

2.81e-05139113539f3c28f89c37bb8cc049c56d2948ea906fb3d86
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DENND2A NUP43 GEMIN5 AMBRA1 STAT5A

2.81e-0513911354efab4421e3448880a1dcf981f6a65131b038010
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FRS2 AMBRA1 CDH8 GPRASP2 AGAP1

3.01e-051411135dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 ABCA1 NRP2 LENG8 MRC2

4.88e-051561135bb505f639dbcad2b788db62d6084c2cb4e884bec
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 RANBP2 COL20A1 LCT CCKAR

5.18e-05158113512661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 RANBP2 COL20A1 LCT CCKAR

5.18e-051581135e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHS1 RANBP2 COL20A1 LCT CCKAR

5.18e-0515811350792c39e6fc0745095af7812de2d50949540d60f
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A GEMIN5 CHD5 POFUT1 TBC1D21

6.01e-051631135953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNRG MAP1A GEMIN5 STAT5A TBC1D21

6.01e-051631135132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellTuft-tuft-1|World / Class top

COL20A1 PPP1R9A TRPS1 CUBN CNTNAP2

6.93e-0516811358ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 C19orf67 PCDHB12 CNTNAP2 CDH8

6.93e-051681135b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 C19orf67 PCDHB12 CNTNAP2 CDH8

6.93e-051681135b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

ABCA1 NRP2 ADAMTS9 SORCS2 LRP4

6.93e-05168113500646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHL1 HLA-E ITGA3 CD82 CDH8

7.13e-051691135225aec04ba762d4c55885257de03a65b63503fbb
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CHL1 HLA-E ITGA3 CD82 CDH8

7.13e-051691135278960f940b646a788360b1c84d641a8d169896b
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D122|Adult / Lineage, Cell type, age group and donor

DLGAP2 TSPEAR ADAMTS9 EBNA1BP2 ACKR1

7.33e-051701135a99cb3d21f8eb926886340ea99491e078e607648
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

DENND2A DLGAP2 TSPEAR NRP2 ADAMTS9

8.63e-05176113598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCelldroplet-Marrow-nan-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACP1 BCL2L1 SLC3A2 MEMO1 ACKR1

8.63e-051761135f92063b72ebfeb9b192281dc63d6bf2759c78554
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

DENND2A DLGAP2 TSPEAR NRP2 ADAMTS9

8.63e-051761135c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellmetastatic_Brain-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

MAP1A AMBRA1 BTBD2 KHDRBS3 GATD1

8.63e-05176113542541dfe20eb29625d47c0bb79bf3c21a2460340
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 MAP1A OTOF CHD5 CNTNAP2

9.10e-051781135a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP2 MAP1A OTOF CHD5 CNTNAP2

9.10e-0517811351bddbc083c36657bd6910f7466126ab325e88176
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

DENND2A DLGAP2 TSPEAR NRP2 ADAMTS9

9.10e-051781135c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

DLGAP2 HLA-E TSPEAR NRP2 OLFM1

9.35e-051791135411620201a860716a8773b92f50f7b94ef34a586
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

CHL1 HLA-E ITGA3 FCN3 CDH8

9.60e-051801135162cec1734e560c068cd61717e40e18dcf92308c
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

CHL1 HLA-E ITGA3 FCN3 CDH8

9.60e-05180113533c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2A COL20A1 CD82 LRP4 AGAP1

1.01e-0418211358a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DLGAP2 OTOF CHD5 OLFM1 FAM131B

1.01e-041821135be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A TRPS1 ADAMTS9 MRC2 LRP4

1.01e-041821135ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CHL1 TRPS1 NRP2 KDM7A AGAP1

1.01e-0418211357b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2A COL20A1 CD82 LRP4 AGAP1

1.01e-041821135e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DENND2A FNDC4 TEX11 MFGE8 SORCS2

1.04e-041831135269afec240a756eec3bbae5f30ec784281af3433
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CCDC169 ITLN1 BCL2L1 MRC2 ACKR1

1.09e-041851135e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

TSPEAR FCN3 MFGE8 ADAMTS9 ACKR1

1.15e-041871135e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

DENND2A NUP43 GEMIN5 AMBRA1 ITGA3

1.18e-041881135c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

HLA-E ITGA3 MED13L CD82 AGAP1

1.18e-0418811351aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

DENND2A NUP43 GEMIN5 AMBRA1 ITGA3

1.18e-0418811359155b9a92496e75646778c025b02947e9e9ec73a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CHL1 DLGAP2 TRPS1 NRP2 CNTNAP2

1.24e-0419011357986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

DENND2A DLGAP2 TSPEAR NRP2 ADAMTS9

1.24e-04190113591bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPECC1L NRP2 CD82 MRC2 LRP4

1.27e-041911135beb5bb42bd53bce01339da9110d374901548793c
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPECC1L NRP2 CD82 MRC2 LRP4

1.27e-0419111356609d85fd2577633dcc067507304a6f9e5865ca3
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPECC1L NRP2 MFGE8 MRC2 LRP4

1.27e-0419111350b3dbbc35d9970d3c749aef16dda59886b960e3d
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

HLA-E BCL2L1 FCN3 CD82 ADAMTS9

1.33e-041931135e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell18-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

DLGAP2 DSCAM CHD5 OLFM1 FAM131B

1.36e-041941135d3c90e1f1228f8ba0ba56105c6cf4f302c388f28
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

HLA-E BCL2L1 FCN3 ADAMTS9 ACKR1

1.40e-041951135fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

C19orf67 PPP1R9A PRDM7 SORCS2 AGAP1

1.43e-041961135ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

PPP1R9A AMBRA1 MED13L LRP4 AGAP1

1.43e-041961135ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A DLGAP2 TSPEAR NRP2 ADAMTS9

1.43e-04196113509a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A DLGAP2 TSPEAR NRP2 ADAMTS9

1.43e-041961135e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

ABCA1 DUSP6 MED13L LENG8 OTOF

1.43e-0419611353729d1444c65cad640377894decc64129bc3fd5b
ToppCell368C-Fibroblasts-Fibroblast-I|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NRP2 CD82 ATAD3A IGHM EBNA1BP2

1.46e-041971135a3d5225b2b0dd5199f3c3f86713a05d48f1be8f4
ToppCell368C-Fibroblasts-Fibroblast-I-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NRP2 CD82 ATAD3A IGHM EBNA1BP2

1.46e-041971135d7a10eca2d810ab87dea570676f0b7041f99f017
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CHL1 DENND2A ABCA1 MRC2 OLFM1

1.53e-041991135ba586690f88fd051f449753bfe7603a2cb431782
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CHL1 DENND2A ABCA1 MRC2 OLFM1

1.53e-04199113506a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellILEUM-inflamed-(7)_ACKR1+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FNDC4 FCN3 ADAMTS9 OLFM1 ACKR1

1.53e-0419911355c799115a6e95bcd896e4ad10bd272705c9a4e2c
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

CHL1 DENND2A ABCA1 MRC2 OLFM1

1.53e-041991135fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CHL1 DENND2A ABCA1 SPECC1L MRC2

1.53e-041991135a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

CHL1 DENND2A ABCA1 MRC2 OLFM1

1.53e-041991135211c3a08f2d484ab7a3368006767289088f0d957
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 DSCAM PPP1R9A CD82 LRP4

1.53e-04199113519a97e27a4758e794ce7246d295e112b47931a48
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 DENND2A SPECC1L MRC2 OLFM1

1.53e-041991135e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

CHL1 DENND2A ABCA1 MRC2 OLFM1

1.53e-0419911351a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PPP1R12A ITGA3 MFGE8 ADAMTS9 WDR1

1.57e-0420011352bc7f462a551292de2501028164573935232f899
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPP1R12A ARL5B ADAMTS9 EBNA1BP2 ACKR1

1.57e-04200113589eae23195d57f1b23a337ff19c9b8a367e22c96
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FCN3 SLC3A2 ADAMTS9 OLFM1 ACKR1

1.57e-04200113550b8788494b744e0f0ec8c4d67a1c90ae09dca65
ToppCell390C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FCN3 SLC3A2 ADAMTS9 OLFM1 ACKR1

1.57e-042001135f5f24273bee3259a4a3be99ba53b88defa1286c0
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Intermediate|1m / Sample Type, Dataset, Time_group, and Cell type.

BTBD2 KHDRBS3 CNTNAP2 OLFM1 FAM131B

1.57e-042001135805f50236113713b02f77aa5e208efb3b3b959d5
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PPP1R12A ARL5B ADAMTS9 EBNA1BP2 ACKR1

1.57e-042001135fa99901388eec28004bef85d84f0d7d5bd4df4a8
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PPP1R12A ITGA3 MFGE8 ADAMTS9 WDR1

1.57e-0420011358b80a65b69b36ed405214564b939452c90aa40d6
Diseaserostral middle frontal gyrus volume measurement

ARRDC1 MAPK6 HSP90AA4P

1.55e-05141053EFO_0010328
Diseasedisease free survival

SLC3A2 CNTNAP2 CDH8

3.44e-05181053EFO_0000409
Diseasebombesin receptor-activated protein C6orf89 measurement

CUBN IGHM

1.25e-0451052EFO_0801428
Diseaseprimary ciliary dyskinesia (is_implicated_in)

DNAH7 BRWD1

1.86e-0461052DOID:9562 (is_implicated_in)
DiseaseCarcinomatosis

DUSP6 TRPS1 BCL2L1 STAT5A MRC2

2.99e-041631055C0205699
DiseaseCarcinoma, Spindle-Cell

DUSP6 TRPS1 BCL2L1 STAT5A MRC2

2.99e-041631055C0205697
DiseaseUndifferentiated carcinoma

DUSP6 TRPS1 BCL2L1 STAT5A MRC2

2.99e-041631055C0205698
DiseaseAnaplastic carcinoma

DUSP6 TRPS1 BCL2L1 STAT5A MRC2

2.99e-041631055C0205696
DiseaseCarcinoma

DUSP6 TRPS1 BCL2L1 STAT5A MRC2

3.08e-041641055C0007097
DiseaseBipolar Disorder

DSCAM DUSP6 HLA-E CCKAR BID MFGE8 CNTNAP2 SORCS2

3.12e-044771058C0005586
Diseasekidney disease (implicated_via_orthology)

NPHS1 CUBN LCT

4.23e-04411053DOID:557 (implicated_via_orthology)
Diseasecorneodesmosin measurement

TRPS1 ACKR1

4.44e-0491052EFO_0801499
Diseaseinformation processing speed, cognitive function measurement

DLGAP2 HSP90AA4P

5.54e-04101052EFO_0004363, EFO_0008354
Diseaseperipheral arterial disease, traffic air pollution measurement

DLGAP2 ABCA1 TRPS1 ANAPC10 SMAD2

6.62e-041941055EFO_0004265, EFO_0007908
Diseaseattention deficit hyperactivity disorder, unipolar depression

DUSP6 CDH8

9.54e-04131052EFO_0003761, EFO_0003888
Diseasemembranous glomerulonephritis (biomarker_via_orthology)

NPHS1 ABCA1

1.11e-03141052DOID:10976 (biomarker_via_orthology)
DiseaseAnimal Mammary Neoplasms

DUSP6 TRPS1 STAT5A MRC2

1.69e-031421054C0024667
DiseaseMammary Carcinoma, Animal

DUSP6 TRPS1 STAT5A MRC2

1.69e-031421054C1257925
Diseasebreast carcinoma (is_marker_for)

BCL2L1 CD82 SMAD2

1.70e-03661053DOID:3459 (is_marker_for)
Diseaseclostridium difficile infection

DLGAP2 TRPS1 SORCS2 CDH8

1.78e-031441054EFO_0009130
Diseaseautism spectrum disorder (implicated_via_orthology)

DSCAM NRP2 CNTNAP2 GPRASP2

2.16e-031521054DOID:0060041 (implicated_via_orthology)
Diseaseurinary microalbumin measurement

CUBN CNTNAP2

2.29e-03201052EFO_0010967
DiseaseMammary Neoplasms, Experimental

DUSP6 TRPS1 STAT5A MRC2

2.32e-031551054C0024668
Diseasemucocutaneous lymph node syndrome

SPECC1L BTBD1 CUBN

2.55e-03761053EFO_0004246
Diseaseinterleukin 10 measurement

DSCAM SORCS2 OLFM1

2.74e-03781053EFO_0004750

Protein segments in the cluster

PeptideGeneStartEntry
HSSYGRNSLEDNSWV

AZI2

336

Q9H6S1
SGNATFYDENSDIWL

ERICH6B

536

Q5W0A0
RSYSVSSADQWSEAT

AGAP1

471

Q9UPQ3
DIGGQESLRSSWNTY

ARL5A

66

Q9Y689
DIGGQESLRSSWNTY

ARL5B

66

Q96KC2
TDNEGSEWKTRYETQ

CCDC169

51

A6NNP5
WQDELSDNQSEYSIG

CHD5

1361

Q8TDI0
LAVSWQATAYASEDG

ATAD3A

581

Q9NVI7
QLGSTNHYWNETVRD

FBXO4

81

Q9UKT5
SSNGSVYTWREAFNE

ABCA1

476

O95477
EGYQNIDITNFSSSW

SPECC1L

1026

Q69YQ0
GYSWSQFSDVEENRT

BCL2L1

21

Q07817
DFEDVWNSSYGVNDS

ACKR1

21

Q16570
WSSDDNLDSDSTYRT

DLGAP2

296

Q9P1A6
SANAWRAYDTASAER

CCKAR

331

P32238
NQETGHWERIYTQSS

AMBRA1

651

Q9C0C7
NISYLNESSGEEWDS

DCAF16

21

Q9NXF7
NDTAWVVEEGYFNSS

ARRDC1

56

Q8N5I2
RDYNSSREDSLQDAW

CD82

126

P27701
TFATGSWDNEENYIS

NUP43

31

Q8NFH3
FDAEETWTNTSANYN

MMP8

196

P22894
AVDSRWSSYGNEATS

RC3H2

946

Q9HBD1
NALVWTASDYADGEA

RANBP2

3001

P49792
WDLQTYSADQRTTGN

RAD52

386

P43351
YSADQRTTGNWESHR

RAD52

391

P43351
SWSSYRAGFGNQESE

FCN3

146

O75636
RNEYEESQWTGERDT

NPHS1

1111

O60500
YSKAEWSDSAQGSES

HLA-E

341

P13747
IATTRGWSTDEANTY

ITLN1

11

Q8WWA0
LARYESWSSSVTQSE

KDM7A

311

Q6ZMT4
EEQSQGSSSYSDWVK

MAP1A

111

P78559
TYAAEEDSTSGNFWL

MED13L

1686

Q71F56
NYTLWRQSDEGSSNQ

MAGEA2

76

P43356
NYTLWSQSDEGSSNE

MAGEA12

76

P43365
INRTTEEDAGSYSCW

CHL1

481

O00533
DSANWTEYQDPRTGS

MFGE8

326

Q08431
DEEQYSWVSSAGSSF

HSP90AB4P

126

Q58FF6
WSEEAGASCDYSRNV

ARRDC5

66

A6NEK1
GDQRSTDWSSQYSMV

LENG8

6

Q96PV6
GSKWNTRESYDDVSS

EBNA1BP2

256

Q99848
AHRYTQVLWSGSEDQ

ITGA3

141

P26006
GNDLELDSSDDWQTY

ITGA3

166

P26006
EALYQSSWDSQFVSG

MAPK6

586

Q16659
PEESWQVYSSAQDSE

OLFM1

56

Q99784
SWSAGENDSYSRNVR

HRNR

131

Q86YZ3
EQISASSTYSDGRWT

NRP2

291

O60462
VSSSAYQIEGAWDAD

LCT

911

P09848
DQTRSGQWRIYGSEE

MRC2

151

Q9UBG0
QSYSQAGITETEWTS

TMPO

221

P42167
GQATGSAWVSSYDRQ

CRNN

156

Q9UBG3
SAWVSSYDRQAESQS

CRNN

161

Q9UBG3
STEQTRTDFSWDGIN

FAM131B

16

Q86XD5
AWDLDSGTNSELSYT

PCDHB12

266

Q9Y5F1
AWDGTTDYQVEETSR

HTATSF1

346

O43719
TQSYPTDWSDDESNN

PACSIN2

391

Q9UNF0
DQIDTRSGFSAYWDG

CUBN

1146

O60494
NEDRSWVFDSYSLTG

GATD1

136

Q8NB37
RDDNLETYWQSDGSQ

ANAPC10

46

Q9UM13
TESARWISQGNYAVS

ADAMTS9

1886

Q9P2N4
AAHTAQGDYQRWVSE

LACTBL1

191

A8MY62
TYDSVTISWTRQNGE

IGHM

251

P01871
LQSSSESSRVDWYAQ

DENND2A

341

Q9ULE3
GSASSEDIWRNYSLD

EFCAB6

271

Q5THR3
TQYSGDAQTEWDLNS

COL20A1

221

Q9P218
ANNTEWDTGYDSDER

FRS2

281

Q8WU20
SEANQWEVAYSGSAT

FNDC3B

616

Q53EP0
WGLAEDSDYTVQVRS

FNDC4

106

Q9H6D8
QQVESRWGYSGTSDR

BTBD1

336

Q9H0C5
ETAVEFSSNYRAWTE

DNAH7

771

Q8WXX0
DYWGQNHSTRSVSAV

GLB1L

271

Q6UWU2
YRDTWEDTGQSPANS

C19orf67

261

A6NJJ6
NYRGENSWFSTQVDT

SLC3A2

311

P08195
SSSRYSDWTADAGIN

BRWD1

861

Q9NSI6
WEGYDELQTDGNRSS

BID

51

P55957
FDGRWYTDINATLSS

DNAAF11

206

Q86X45
VSQSTTSDYQWDVSR

MTDH

356

Q86UE4
ETYDSYGQEEWTNSR

KHDRBS3

311

O75525
SAIATQGRYSSSDWV

CNTNAP2

96

Q9UHC6
ERWSSYQNQTDNSVS

DCLRE1A

211

Q6PJP8
NDEQYAWESSLRGSF

HSP90AA4P

96

Q58FG1
TSDSDQNFDYLSDWG

CDH8

766

P55286
RFQQVESRWGYSGTS

BTBD2

376

Q9BX70
VLYDESSSDWNENTG

DUSP6

96

Q16828
ASTERPSTDSQGYWN

SLC17A4

76

Q9Y2C5
DQSGQTFDQSSETWR

ATP4A

416

P20648
VRYQATDGTVGSWDD

OTOF

116

Q9HC10
NWQDSSVSYAAGALT

MEMO1

281

Q9Y316
TGISFSASYREQWSQ

POFUT1

166

Q9H488
SVTGTEDQELSWYRN

DSCAM

336

O60469
TGYFSWQSSQDERLT

TBC1D21

71

Q8IYX1
LTSYDWSDRDDATQG

SYNRG

891

Q9UMZ2
RSKQEAYVDSWSGSE

GPRASP2

271

Q96D09
AYVDSWSGSEDEASN

GPRASP2

276

Q96D09
TEDEEAANSGYSWLI

PRDM7

281

Q9NQW5
ISENWRVDSAATSGY

ACP1

36

P24666
RIWEETGNYTFSSDS

SLC46A3

31

Q7Z3Q1
SSQYSNTEERLWVHG

SEMG1

156

P04279
SRQCGEEDYSSWELS

SORCS2

646

Q96PQ0
INNDYSEWDLSTDAG

SLC38A7

6

Q9NVC3
EDYSGLSVSWSQFNR

STAT5B

546

P51692
SDDGTVRIWDYTQDA

WDR17

586

Q8IZU2
INYWDSETGENDSFA

WDR1

346

O75083
NSEWEEAYINSGRTG

PMIS2

116

A0A1W2PS18
EDYSGLSVSWSQFNR

STAT5A

546

P42229
DSSRQNGTEATSYYW

TRPS1

421

Q9UHF7
NTIDQWDTTGLYSFS

SMAD2

91

Q15796
WDTTGLYSFSEQTRS

SMAD2

96

Q15796
YTGEDRDRAFGWSTN

ZNF721

181

Q8TF20
VSASYDGTAQVWDAL

GEMIN5

656

Q8TEQ6
LTYISEGWENVDDSS

UNC5CL

311

Q8IV45
WRQAASSFEVQNYTD

TEX11

421

Q8IYF3
LAWLSTYVADSGSNQ

TMUB2

51

Q71RG4
EANQTIATSGAYDWE

TSPEAR

466

Q8WU66
QVYDATSWDGTRSQD

WDR73

301

Q6P4I2
DAGTDQDSRWRLQYD

TM7SF3

181

Q9NS93
ARVSSWDSQSYDIEQ

LEUTX

131

A8MZ59
YWTDAGTDRIEVANT

LRP4

831

O75096
NLYWTDTGRNTIEAS

LRP4

1441

O75096
RSTGVSFWTQDSDEN

PPP1R12A

851

O14974
VRSRYNSDWGETGTE

PPP1R9A

406

Q9ULJ8