Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP8B3 SMCHD1 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ATP2C1 ABCD3 DDX23 MACF1 CHD6 ABCC2 DYNC1H1

2.06e-0844114417GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

ATP8B3 SMCHD1 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ATP2C1 DNAH17 ABCD3 DDX23 MACF1 CHD6 ABCC2 DYNC1H1 CDK7

9.50e-0861414419GO:0140657
GeneOntologyMolecularFunctionpyrophosphatase activity

ATP8B3 ENPP2 SMCHD1 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ATP2C1 ABCD3 DDX23 MACF1 CHD6 ABCC2 DYNC1H1

3.50e-0583914418GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ATP8B3 ENPP2 SMCHD1 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ATP2C1 ABCD3 DDX23 MACF1 CHD6 ABCC2 DYNC1H1

3.55e-0584014418GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ATP8B3 ENPP2 SMCHD1 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ATP2C1 ABCD3 DDX23 MACF1 CHD6 ABCC2 DYNC1H1

3.55e-0584014418GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ATP8B3 SMCHD1 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ATP2C1 ABCD3 DDX23 MACF1 CHD6 ABCC2 DYNC1H1

4.46e-0577514417GO:0017111
GeneOntologyMolecularFunctioncarbohydrate binding

KRT1 CALR3 ENPP2 SIGLEC14 APCS SIGLEC5 ADGRL1 PPP1R3A ACAN GALNT8

8.63e-0531014410GO:0030246
GeneOntologyMolecularFunctionATP-dependent activity, acting on DNA

CHD3 CHD7 MSH2 DHX9 CHD6 CDK7

3.20e-041271446GO:0008094
GeneOntologyMolecularFunctionribonucleoprotein complex binding

NVL GEMIN5 OLA1 DHX9 XPO5 PRMT7 BAG6

7.49e-042061447GO:0043021
GeneOntologyMolecularFunctionRISC complex binding

DHX9 XPO5

7.60e-0461442GO:1905172
GeneOntologyCellularComponentHCN channel complex

HCN3 HCN2

2.88e-0441462GO:0098855
GeneOntologyCellularComponentHULC complex

UBE2A UBE2B

2.88e-0441462GO:0033503
GeneOntologyCellularComponentleading edge membrane

DOCK8 GRIA2 HCN2 EPHA2 CNTNAP2 MACF1 USH2A

6.97e-042101467GO:0031256
GeneOntologyCellularComponentpresynaptic membrane

GABRB2 ADGRL1 GRIA2 GABBR2 PTPRD ITSN2 CNTNAP2 STX11

7.49e-042771468GO:0042734
GeneOntologyCellularComponentneuronal cell body

MAOB PTBP2 HCN3 MAGOHB GRIA2 CASR KCNB2 HCN2 CIT TXNRD1 ACAN CNTNAP2 DLG3 USH2A DYNC1H1

7.60e-0483514615GO:0043025
GeneOntologyCellularComponentcell leading edge

DOCK8 GRIA2 HCN2 CIT FAT1 DST EPHA2 CNTNAP2 MACF1 USH2A APBB1IP

7.91e-0450014611GO:0031252
GeneOntologyCellularComponentcell body

MAOB PTBP2 HCN3 MAGOHB GRIA2 CASR KCNB2 HCN2 CIT TXNRD1 ACAN CNTNAP2 CD40LG DLG3 USH2A DYNC1H1

7.93e-0492914616GO:0044297
DomainDNA/RNA_helicase_DEAH_CS

CHD3 CHD7 DHX9 CHD6

1.40e-04351424IPR002464
DomainAFAP

AFAP1L1 AFAP1

1.71e-0431422IPR030113
DomainDUF3528

HOXA11 HOXD11

1.71e-0431422IPR021918
DomainDUF3528

HOXA11 HOXD11

1.71e-0431422PF12045
DomainDEAH_ATP_HELICASE

CHD3 CHD7 DHX9 CHD6

1.93e-04381424PS00690
DomainNebulin

NEBL NEB

3.41e-0441422PF00880
DomainIon_trans_N

HCN3 HCN2

3.41e-0441422IPR013621
DomainNEBULIN

NEBL NEB

3.41e-0441422PS51216
DomainNEBU

NEBL NEB

3.41e-0441422SM00227
DomainNebulin

NEBL NEB

3.41e-0441422IPR013998
DomainIon_trans_N

HCN3 HCN2

3.41e-0441422PF08412
DomainNebulin_repeat

NEBL NEB

3.41e-0441422IPR000900
Domain-

SAMD9 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ABCD3 DDX23 DLG3 CHD6 ABCC2 DYNC1H1

5.64e-04746142153.40.50.300
DomainScramblase

PLSCR5 PLSCR1

5.65e-0451422PF03803
DomainScramblase

PLSCR5 PLSCR1

5.65e-0451422IPR005552
DomainP-loop_NTPase

SAMD9 ABCB5 NVL CHD3 CHD7 MSH2 OLA1 ATAD2 DHX9 ASPM ABCD3 DDX23 DLG3 CHD6 ABCC2 DYNC1H1

7.31e-0484814216IPR027417
DomainChromo_domain

CHD3 CHD7 CHD6

7.75e-04241423IPR023780
Domain-

CALR3 APCS FAT1 CNTNAP2 USH2A

7.92e-049514252.60.120.200
DomainAAA

ABCB5 NVL ATAD2 ABCD3 ABCC2 DYNC1H1

8.20e-041441426SM00382
DomainAAA+_ATPase

ABCB5 NVL ATAD2 ABCD3 ABCC2 DYNC1H1

8.20e-041441426IPR003593
DomainBRK

CHD7 CHD6

8.44e-0461422SM00592
Domain-

DST MACF1

8.44e-04614223.90.1290.10
DomainGAR

DST MACF1

8.44e-0461422PS51460
DomainBRK_domain

CHD7 CHD6

8.44e-0461422IPR006576
DomainGAS2

DST MACF1

8.44e-0461422PF02187
Domain-

DST MACF1

8.44e-04614223.30.920.20
DomainBRK

CHD7 CHD6

8.44e-0461422PF07533
DomainGAS_dom

DST MACF1

8.44e-0461422IPR003108
DomainGAS2

DST MACF1

8.44e-0461422SM00243
DomainChromo

CHD3 CHD7 CHD6

9.84e-04261423PF00385
DomainPlectin

DST MACF1

1.18e-0371422PF00681
DomainPlectin_repeat

DST MACF1

1.18e-0371422IPR001101
DomainPLEC

DST MACF1

1.18e-0371422SM00250
DomainCHROMO_1

CHD3 CHD7 CHD6

1.23e-03281423PS00598
DomainABC_TM1F

ABCB5 ABCD3 ABCC2

1.23e-03281423PS50929
DomainABC1_TM_dom

ABCB5 ABCD3 ABCC2

1.23e-03281423IPR011527
DomainCHROMO_2

CHD3 CHD7 CHD6

1.23e-03281423PS50013
DomainSH3

DOCK2 NEBL NEB DST ITSN2 MACF1 DLG3

1.34e-032161427PS50002
DomainHelicase_C

CHD3 CHD7 DHX9 DDX23 CHD6

1.35e-031071425PF00271
DomainHELICc

CHD3 CHD7 DHX9 DDX23 CHD6

1.35e-031071425SM00490
DomainHelicase_C

CHD3 CHD7 DHX9 DDX23 CHD6

1.41e-031081425IPR001650
DomainHELICASE_CTER

CHD3 CHD7 DHX9 DDX23 CHD6

1.47e-031091425PS51194
DomainHELICASE_ATP_BIND_1

CHD3 CHD7 DHX9 DDX23 CHD6

1.47e-031091425PS51192
DomainDEXDc

CHD3 CHD7 DHX9 DDX23 CHD6

1.47e-031091425SM00487
DomainSH3_domain

DOCK2 NEBL NEB DST ITSN2 MACF1 DLG3

1.48e-032201427IPR001452
DomainHelicase_ATP-bd

CHD3 CHD7 DHX9 DDX23 CHD6

1.53e-031101425IPR014001
DomainEnoyl-CoA_hyd/isom_CS

ECHS1 HADHA

1.56e-0381422IPR018376
DomainSNF2_N

CHD3 CHD7 CHD6

1.82e-03321423IPR000330
DomainSNF2_N

CHD3 CHD7 CHD6

1.82e-03321423PF00176
DomainChromodomain-like

CHD3 CHD7 CHD6

1.82e-03321423IPR016197
DomainChromo/shadow_dom

CHD3 CHD7 CHD6

1.99e-03331423IPR000953
DomainCHROMO

CHD3 CHD7 CHD6

1.99e-03331423SM00298
DomainENOYL_COA_HYDRATASE

ECHS1 HADHA

2.48e-03101422PS00166
DomainPTPc

PTPRT PTPN4 PTPRD

2.56e-03361423SM00194
DomainANF_lig-bd_rcpt

GRIA2 CASR GABBR2

2.77e-03371423IPR001828
DomainANF_receptor

GRIA2 CASR GABBR2

2.77e-03371423PF01094
DomainLAM_G_DOMAIN

FAT1 CNTNAP2 USH2A

2.99e-03381423PS50025
DomainDHR-1_domain

DOCK2 DOCK8

3.02e-03111422IPR027007
DomainDHR_2

DOCK2 DOCK8

3.02e-03111422PS51651
DomainDHR_1

DOCK2 DOCK8

3.02e-03111422PS51650
DomainDHR-2

DOCK2 DOCK8

3.02e-03111422PF06920
DomainDOCK

DOCK2 DOCK8

3.02e-03111422IPR026791
DomainDOCK_C

DOCK2 DOCK8

3.02e-03111422IPR010703
DomainDOCK-C2

DOCK2 DOCK8

3.02e-03111422PF14429
DomainDHR-2

DOCK2 DOCK8

3.02e-03111422IPR027357
DomainPeripla_BP_I

GRIA2 CASR GABBR2

3.22e-03391423IPR028082
DomainTYR_PHOSPHATASE_PTP

PTPRT PTPN4 PTPRD

3.22e-03391423PS50055
DomainLaminin_G_2

FAT1 CNTNAP2 USH2A

3.46e-03401423PF02210
DomainMit_uncoupling

SLC25A14 SLC25A30

3.60e-03121422IPR002030
DomainPTPase_domain

PTPRT PTPN4 PTPRD

3.71e-03411423IPR000242
DomainY_phosphatase

PTPRT PTPN4 PTPRD

3.71e-03411423PF00102
DomainABC_transporter_CS

ABCB5 ABCD3 ABCC2

3.98e-03421423IPR017871
DomainLamG

FAT1 CNTNAP2 USH2A

4.54e-03441423SM00282
DomainK_chnl_volt-dep_EAG/ELK/ERG

HCN3 HCN2

4.92e-03141422IPR003938
DomainGPCR_3_CS

CASR GABBR2

4.92e-03141422IPR017979
DomainABC_tran

ABCB5 ABCD3 ABCC2

5.80e-03481423PF00005
DomainABC_TRANSPORTER_2

ABCB5 ABCD3 ABCC2

5.80e-03481423PS50893
DomainEF-hand_1

TCHH DST ITSN2 MACF1 CAPS2

6.14e-031521425PF00036
DomainABC_TRANSPORTER_1

ABCB5 ABCD3 ABCC2

6.14e-03491423PS00211
DomainABC_transporter-like

ABCB5 ABCD3 ABCC2

6.50e-03501423IPR003439
DomainConA-like_dom

CALR3 APCS PTPRT FAT1 CNTNAP2 USH2A

6.63e-032191426IPR013320
DomainECH_1

ECHS1 HADHA

7.24e-03171422PF00378
DomainCrotonase_core_superfam

ECHS1 HADHA

7.24e-03171422IPR001753
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK2 DOCK8 PTBP2 SMCHD1 CHD3 CHD7 MSH2 NUF2 OLA1 DHX9 XPO5 ANAPC2 DDX23 MACF1 DYNC1H1 APBB1IP

4.40e-095821481620467437
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

MSH2 UBE2A UBE2B AFAP1 XPO5 EPHA2 HADHA DYNC1H1

4.38e-08118148827377895
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT1 PTBP2 PSMA2 SMCHD1 ABCB5 GRIA2 CHD3 NDUFA5 NEB CCDC27 DST SACS CTR9 FAM186A ITSN2 ASPM DDX23 MACF1 DLG3 CHD6 HADHA ABCC2 BBOF1

4.94e-0814421482335575683
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

DOCK2 DOCK8 PSMA2 SMCHD1 RNF113A MAGOHB CHD3 CHD7 MSH2 OLA1 CIT TXNRD1 KMT2C XPO5 CTR9 DDX23 HADHA BAG6 DYNC1H1 CDK7

5.23e-0811031482034189442
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

H1-10 EYA4 RBBP6 SMCHD1 MAGOHB ZNF205 CHD3 CHD7 MSH2 NDUFA5 DHX9 HOXA11 KMT2C DST CTR9 ANAPC2 DDX23 CHD6 HADHA PRPF38A MGA

1.51e-0712941482130804502
Pubmed

A human MAP kinase interactome.

RBBP6 RAP1GAP2 ADGRL1 NEB KMT2C DST ITSN2 MACF1 AKAP13 CHD6 MBD5 CPLANE1 MGA

1.82e-074861481320936779
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KRT1 SMCHD1 GEMIN5 MSH2 CIT DHX9 XPO5 CNTNAP2 AKAP13

2.30e-07202148933005030
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

PSMA2 E2F7 MSH2 NUF2 OLA1 ECHS1 AFAP1L1 DHX9 KMT2C TCHH XPO5 ASPM ABCD3 DDX23 DLG3 AKAP13 HADHA BCAR3 BAG6 DYNC1H1

5.85e-0712841482017353931
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

SMCHD1 NVL MAGOHB MSH2 CIT DHX9 AFAP1 DST CTR9 EPHA2 DDX23 MACF1 HADHA PRPF38A

9.76e-076601481432780723
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

H1-10 PSMA2 SMCHD1 GEMIN5 CHD7 MSH2 ATAD2 DHX9 DST CTR9 ASPM ABCD3 DDX23 MACF1 AKAP13 HADHA PRPF38A MGA BAG6 DYNC1H1

1.31e-0613531482029467282
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

RBBP6 PSMA2 SMCHD1 NVL GEMIN5 CHD3 MSH2 OLA1 NPLOC4 DHX9 TXNRD1 BROX UBE2A XPO5 CTR9 DDX23 CDK7

1.65e-0610141481732416067
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

H1-10 SMCHD1 CHD3 MSH2 OLA1 ECHS1 CIT DHX9 DST SACS ABCD3 DDX23 MACF1 HADHA MGA BAG6 DYNC1H1

1.88e-0610241481724711643
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

DHX9 ANAPC2 DYNC1H1 ANAPC4

3.13e-0624148433705438
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

KRT1 H1-10 RBBP6 SMCHD1 MAGOHB GEMIN5 CHD7 MSH2 NDUFA5 ECHS1 DHX9 XPO5 CTR9 ABCD3 DDX23 CHD6 HADHA PRPF38A DYNC1H1

3.55e-0613181481930463901
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

CHD3 CHD7 OLA1 XPO5 CTR9 ANAPC2 MACF1 CHD6 ANAPC4

3.66e-06282148923667531
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

H1-10 SMCHD1 NVL GEMIN5 CHD7 MSH2 ATAD2 DST XPO5 DDX23 MACF1 HADHA DYNC1H1

4.82e-066531481322586326
Pubmed

Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.

RNF113A MSH2 AFAP1 EPHA2 MACF1 HADHA BAG6 DYNC1H1

8.06e-06235148828378594
Pubmed

Functional proteomics mapping of a human signaling pathway.

DOCK8 RBBP6 CHD3 DST XPO5 CTR9 ANAPC2 MACF1 CHD6 MGA BAG6 DYNC1H1

9.31e-065911481215231748
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

KRT1 H1-10 SMCHD1 MAGOHB GEMIN5 MSH2 NDUFA5 OLA1 NPLOC4 DHX9 TXNRD1 CTR9 ABCD3 DDX23 MACF1 AKAP13 HADHA BAG6 DYNC1H1

9.73e-0614151481928515276
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

ABCB5 NEB CIT KMT2C DST PTPRD MACF1 BAG6 DYNC1H1

1.06e-05322148926514267
Pubmed

Defining the membrane proteome of NK cells.

DOCK2 KRT1 DOCK8 NVL GEMIN5 MSH2 NUF2 OLA1 CIT DHX9 ATP2C1 LPXN ABCD3 AKAP13 BAG6 PLSCR1 DYNC1H1

1.06e-0511681481719946888
Pubmed

Human transcription factor protein interaction networks.

H1-10 ASXL1 EYA4 RBBP6 PSMA2 SMCHD1 CHD3 CHD7 NDUFA5 CIT KMT2C FAT1 DST HOXD11 ABCD3 CHD6 HADHA MGA DYNC1H1

1.12e-0514291481935140242
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

KRT1 RBBP6 PTBP2 CHD7 NDUFA5 DHX9 AFAP1 DST SACS ABCD3 DDX23 MACF1 CHD6 HADHA PRPF38A DYNC1H1

1.62e-0510821481638697112
Pubmed

Global proteomics of Ubqln2-based murine models of ALS.

EYA4 NEBL SMCHD1 NUF2 NPLOC4 DST ITSN2 ABCD3

1.72e-05261148833277362
Pubmed

Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus.

SIGLEC14 SIGLEC5

1.80e-052148224799499
Pubmed

FAT1 and MSH2 Are Predictive Prognostic Markers for Chinese Osteosarcoma Patients Following Chemotherapeutic Treatment.

MSH2 FAT1

1.80e-052148235279875
Pubmed

Hyperpolarization-activated cyclic nucleotide-modulated 'HCN' channels confer regular and faster rhythmicity to beating mouse embryonic stem cells.

HCN3 HCN2

1.80e-052148218033814
Pubmed

ASPM and citron kinase co-localize to the midbody ring during cytokinesis.

CIT ASPM

1.80e-052148217534152
Pubmed

The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.

UBE2A UBE2B

1.80e-052148215169909
Pubmed

Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.

UBE2A UBE2B

1.80e-052148212556476
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

1.80e-052148211002341
Pubmed

Two new cases of interstitial 7q35q36.1 deletion including CNTNAP2 and KMT2C.

KMT2C CNTNAP2

1.80e-052148234582124
Pubmed

Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity.

CASR HIF1AN

1.80e-052148215239670
Pubmed

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

UBE2A UBE2B

1.80e-05214821717990
Pubmed

Functional equivalence and rescue among group 11 Hox gene products in vertebral patterning.

HOXA11 HOXD11

1.80e-05214828660870
Pubmed

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.

UBE2A UBE2B

1.80e-05214821559696
Pubmed

The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.

UBE2A UBE2B

1.80e-052148211885984
Pubmed

DOCK family proteins: key players in immune surveillance mechanisms.

DOCK2 DOCK8

1.80e-052148231630188
Pubmed

The human uncoupling proteins 5 and 6 (UCP5/SLC25A14 and UCP6/SLC25A30) transport sulfur oxyanions, phosphate and dicarboxylates.

SLC25A14 SLC25A30

1.80e-052148231356773
Pubmed

PTPRD and CNTNAP2 as markers of tumor aggressiveness in oligodendrogliomas.

PTPRD CNTNAP2

1.80e-052148235982066
Pubmed

Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11.

HOXA11 HOXD11

1.80e-05214827596412
Pubmed

Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14.

SIGLEC14 SIGLEC5

1.80e-052148226459514
Pubmed

Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.

UBE2A UBE2B

1.80e-052148231683936
Pubmed

Immunocytochemical localization of the GABAB2 receptor subunit in the glomeruli of the mouse main olfactory bulb.

GABRB2 GABBR2

1.80e-052148216714082
Pubmed

Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.

NEBL NEB

1.80e-052148219851499
Pubmed

A novel hemizygous CD40L mutation of X-linked hyper IgM syndromes and compound heterozygous DOCK8 mutations of hyper IgE syndromes in two Chinese families.

DOCK8 CD40LG

1.80e-052148238587548
Pubmed

RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.

UBE2A UBE2B

1.80e-052148228806395
Pubmed

Absence of mutations in the HOXA11 and HOXD11 genes in children with congenital renal malformations.

HOXA11 HOXD11

1.80e-052148219255789
Pubmed

Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development.

HOXA11 HOXD11

1.80e-052148216581055
Pubmed

CHD6 is a DNA-dependent ATPase and localizes at nuclear sites of mRNA synthesis.

CHD3 CHD6

1.80e-052148217027977
Pubmed

HCN3 ion channels: roles in sensory neuronal excitability and pain.

HCN3 HCN2

1.80e-052148231290157
Pubmed

Immune regulatory functions of DOCK family proteins in health and disease.

DOCK2 DOCK8

1.80e-052148223911989
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

EYA4 PSMA2 SMCHD1 MSH2 NPLOC4 PTPN4 ATP2C1 PTPRD SNX6 XPO5 CTR9 EPHA2 ABCD3 PRORP BAG6

1.89e-059741481528675297
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

DST CTR9 ITSN2 CNTNAP2 MACF1 MBD5

2.07e-05130148612421765
Pubmed

Differential gene expression in migrating cortical interneurons during mouse forebrain development.

CHL1 PTPRT PTPRD

2.09e-0513148320151419
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NEBL RBBP6 GEMIN5 CHD7 OLA1 ATAD2 CIT KMT2C AFAP1 DST SLC25A40 CTR9 ITSN2 ABCD3 MACF1 DLG3 CHD6 PRPF38A CDK7

2.12e-0514971481931527615
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

RBBP6 PTBP2 CHD3 MSH2 OLA1 DHX9 PPP1R3A XPO5 CTR9 DDX23 HADHA BAG6

2.49e-056531481233742100
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

PSMA2 NVL APCS ZNF205 CHD3 MSH2 KMT2C PTPN4 UBE2A FRZB ANAPC2 LPXN PRPF38A STX11 BAG6 PLSCR1

2.57e-0511241481621900206
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

SMCHD1 CHD7 DHX9 BROX DST ASPM DLG3 CHD6 MGA

2.73e-05363148914691545
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

RBBP6 SMCHD1 CIT NPLOC4 CTR9 ANAPC2 MACF1 ANAPC4

2.92e-05281148824163370
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

H1-10 SMCHD1 GEMIN5 SNX6 ANAPC2 ASPM ABCD3 DDX23 USH2A DYNC1H1 ANAPC4 BBOF1

3.19e-056701481222990118
Pubmed

The apical ectodermal ridge is a timer for generating distal limb progenitors.

HOXA11 HOXD11 FGFR2

3.31e-0515148318359901
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

KRT1 H1-10 PSMA2 E2F7 GEMIN5 CHD3 CHD7 DHX9 XPO5 CTR9 MACF1 CHD6 HADHA FGFR2 BAG6 DYNC1H1

3.49e-0511531481629845934
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

RNF113A MAGOHB GRIA2 DST CTR9 EPHA2 ANAPC2 FGFR2 MMP1 BCAR3 CPLANE1 CFAP97 ANAPC4 CDK7

3.68e-059101481436736316
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

SAMD9 MSH2 AFAP1 DST ASPM ABCD3 MACF1 PRMT7 ANAPC4 CDK7

3.71e-054721481038943005
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

KRT1 DOCK8 GEMIN5 ADGRL1 GRIA2 CHD3 OLA1 CIT DHX9 AFAP1 DST SACS ITSN2 ABCD3 MACF1 DLG3 HADHA DYNC1H1

4.00e-0514311481837142655
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

RBBP6 SMCHD1 GEMIN5 DHX9 FAT1 FOXRED2 UBE2B AFAP1 DST SNX6 XPO5 LPL MACF1 AKAP13 HADHA DYNC1H1 CDK7

4.00e-0512971481733545068
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

DOCK2 H1-10 PSMA2 OLA1 ECHS1 DHX9 TXNRD1 DST LPXN MACF1 AKAP13 HADHA DYNC1H1

4.43e-058071481330575818
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

H1-10 E2F7 DHX9 HADHA MGA BAG6 DYNC1H1

4.76e-05221148729991511
Pubmed

Functional interaction of ubiquitin ligase RNF167 with UBE2D1 and UBE2N promotes ubiquitination of AMPA receptor.

GRIA2 UBE2A UBE2B

4.91e-0517148333650289
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK2 PIKFYVE ATP2C1 SACS DNAH17 MACF1 PRORP PRMT7 MBD5 MGA

5.33e-054931481015368895
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ASXL1 CHD7 KMT2C DST XPO5 MACF1 CHD6

5.33e-05225148712168954
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

KRT1 PSMA2 SMCHD1 NDUFA5 OLA1 DHX9 BROX XPO5 MACF1 HADHA BAG6 DYNC1H1

5.35e-057071481219738201
Pubmed

Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.

SIGLEC14 SIGLEC5

5.38e-053148211579105
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

5.38e-053148212399109
Pubmed

The human RAD18 gene product interacts with HHR6A and HHR6B.

UBE2A UBE2B

5.38e-053148210908344
Pubmed

Mast Cell-Specific Expression of Human Siglec-8 in Conditional Knock-in Mice.

SIGLEC14 SIGLEC5

5.38e-053148230577572
Pubmed

A novel Siglec-F+ neutrophil subset in the mouse nasal mucosa exhibits an activated phenotype and is increased in an allergic rhinitis model.

SIGLEC14 SIGLEC5

5.38e-053148232247614
Pubmed

Enhanced genomic instability and defective postreplication repair in RAD18 knockout mouse embryonic stem cells.

UBE2A UBE2B

5.38e-053148212509447
Pubmed

UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.

UBE2A UBE2B

5.38e-053148238182926
Pubmed

The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.

CHD7 CHD6

5.38e-053148228533432
Pubmed

Deletion of a HoxD enhancer induces transcriptional heterochrony leading to transposition of the sacrum.

HOXA11 HOXD11

5.38e-05314829250683
Pubmed

Complex formation with the Type B gamma-aminobutyric acid receptor affects the expression and signal transduction of the extracellular calcium-sensing receptor. Studies with HEK-293 cells and neurons.

CASR GABBR2

5.38e-053148217591780
Pubmed

Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagens.

UBE2A UBE2B

5.38e-053148210884424
Pubmed

E2F7 drives autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not in human carcinomas.

ENPP2 E2F7

5.38e-053148237358838
Pubmed

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.

SIGLEC14 SIGLEC5

5.38e-053148225497369
Pubmed

Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.

SIGLEC14 SIGLEC5

5.38e-053148224698729
Pubmed

Functional specificity of the Hoxa13 homeobox.

HOXA11 HOXD11

5.38e-053148211688568
Pubmed

RNF168 forms a functional complex with RAD6 during the DNA damage response.

UBE2A UBE2B

5.38e-053148223525009
Pubmed

Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates.

SIGLEC14 SIGLEC5

5.38e-053148217012248
Pubmed

Siglec-F is induced by granulocyte-macrophage colony-stimulating factor and enhances interleukin-4-induced expression of arginase-1 in mouse macrophages.

SIGLEC14 SIGLEC5

5.38e-053148231520477
Pubmed

Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.

SIGLEC14 SIGLEC5

5.38e-053148223710953
Pubmed

Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.

SIGLEC14 SIGLEC5

5.38e-053148219783675
Pubmed

Coordinated molecular control of otic capsule differentiation: functional role of Wnt5a signaling and opposition by sfrp3 activity.

ACAN FRZB

5.38e-053148218991062
Pubmed

DNA methylation profiling identifies EYA4 gene as a prognostic molecular marker in hepatocellular carcinoma.

EYA4 HOXA11

5.38e-053148224306662
Pubmed

Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls.

SIGLEC14 SIGLEC5

5.38e-053148232134149
Pubmed

Siglec-F is a novel intestinal M cell marker.

SIGLEC14 SIGLEC5

5.38e-053148227524237
Pubmed

A family of hyperpolarization-activated mammalian cation channels.

HCN3 HCN2

5.38e-05314829634236
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

ASXL1 PSMA2 SMCHD1 CHD3 NUF2 KMT2C GALNT8 ABCD3 MBD5 MGA

5.51e-054951481027705803
Pubmed

RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells.

UBE2A UBE2B CTR9

5.88e-0518148319410543
InteractionEED interactions

CHL1 KRT1 H1-10 ASXL1 RBBP6 SMCHD1 HCN3 NVL MAGOHB GEMIN5 CHD3 CHD7 MSH2 OLA1 ATAD2 CIT DHX9 SNX6 XPO5 ITSN2 ABCD3 MACF1 HADHA PRPF38A MGA BAG6 DYNC1H1

3.54e-06144514427int:EED
InteractionRAD18 interactions

H1-10 RBBP6 MAGOHB MSH2 UBE2A UBE2B AFAP1 XPO5 CTR9 EPHA2 DDX23 HADHA PRPF38A DYNC1H1

5.24e-0645714414int:RAD18
InteractionLRRC31 interactions

KRT1 SMCHD1 GEMIN5 MSH2 CIT DHX9 XPO5 CNTNAP2 AKAP13

1.70e-052051449int:LRRC31
GeneFamilyPhospholipid scramblases

PLSCR5 PLSCR1

3.56e-0451092954
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

EYA4 CHD7 NUF2 ECHS1 DHX9 SORCS1 TXNRD1 FAT1 AFAP1 PTPRD DMRT2 SACS CTR9 ITSN2 ABCD3 CHD6 FGFR2 BCAR3 STX11

3.20e-06100914519M157
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ASXL1 SMCHD1 NVL MSH2 TXNRD1 PIKFYVE PTPN4 FAT1 AFAP1 ATP2C1 DST SACS ITSN2 MACF1 AKAP13 BCAR3 PLSCR1

5.49e-0685614517M4500
CoexpressionGSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_DN

H1-10 SAMD9 RNF113A CHD7 HIF1AN PRMT7 PLSCR1 APBB1IP

1.46e-051971458M9580
CoexpressionBENPORATH_CYCLING_GENES

ASXL1 RNF113A MSH2 NUF2 ATAD2 CIT TXNRD1 AFAP1 CTR9 FRZB AKAP13 ABCC2 CPLANE1 CDK7

1.54e-0564814514M8156
CoexpressionHE_LIM_SUN_FETAL_LUNG_C7_PROLIFERATING_SCHWANN_CELL

ATP8B3 NEBL MAOB ENPP2 PSMA2 E2F7 PARD3B NUF2 ATAD2 NPLOC4 NSUN7 BROX FOXRED2 PTPRD SLC25A40 LPL FRZB ASPM

2.21e-05105414518M45798
CoexpressionBAELDE_DIABETIC_NEPHROPATHY_DN

NEBL PSMA2 CHD3 MSH2 FAT1 DST PTPRD LPL FGFR2 BCAR3 PLSCR1

3.34e-0543714511M4665
CoexpressionGEORGES_TARGETS_OF_MIR192_AND_MIR215

PTBP2 HCN3 SLC25A30 CHD7 NUF2 ATAD2 CIT ZNF248 AFAP1L1 OVOL1 DST SLC25A40 ASPM MACF1 PRPF38A BBOF1

3.64e-0589214516M18120
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EYA4 PARD3B PTPRT FAT1 CRYGS DMRT2 CNTNAP2 CAPS2

1.50e-081341468657ad905b40ec3f82acdef824431b8276d291ef7
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 PARD3B MSH2 ATAD2 ABCD3 NDUFAF6 CHD6 ABCC2

2.52e-071931468503a979328c68b096680b71359a26f02fafdff35
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

CHL1 ASXL1 SAMD9 SMCHD1 PARD3B CHD3 MACF1 CHD6

3.06e-071981468ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

CHL1 GRIA2 CHD3 PTPRT SORCS1 DST PTPRD LPL

3.18e-0719914681b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

CHL1 GRIA2 CHD3 PTPRT SORCS1 DST PTPRD LPL

3.18e-0719914684bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 RHBDF2 DOCK8 CPED1 BROX KBTBD12 AKAP13 APBB1IP

3.30e-072001468a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 RHBDF2 DOCK8 CPED1 BROX KBTBD12 AKAP13 APBB1IP

3.30e-072001468dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 RHBDF2 DOCK8 CPED1 BROX KBTBD12 AKAP13 APBB1IP

3.30e-0720014683bba5219453322198e8fdb0921d5f8c403598751
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SAMD9 DOCK8 SMCHD1 KMT2C ITSN2 MACF1 AKAP13 DYNC1H1

3.30e-07200146812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 RHBDF2 DOCK8 CPED1 BROX KBTBD12 AKAP13 APBB1IP

3.30e-07200146821bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 RHBDF2 DOCK8 CPED1 BROX KBTBD12 AKAP13 APBB1IP

3.30e-072001468a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK2 RHBDF2 DOCK8 CPED1 BROX KBTBD12 AKAP13 APBB1IP

3.30e-07200146833036d21c1c82109284473a515c4f890b33fdd5c
ToppCelldroplet-Spleen-nan-3m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

H1-10 RAP1GAP2 E2F7 SIGLEC5 TCHH TMEM40 BBOF1

1.52e-061701467dbd6c9c7be824a1ff1b31af791064127cafbd194
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ODAD2 NEB SORCS1 FAT1 PTPRD USH2A

2.56e-0618414672cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ODAD2 NEB SORCS1 FAT1 PTPRD USH2A

2.56e-061841467ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB2 ODAD2 NEB SORCS1 FAT1 PTPRD USH2A

2.56e-0618414672b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

CHL1 EYA4 NEBL FAT1 EPHA2 SERPINB11 FGFR2

2.75e-061861467d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GABRB2 DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.40e-06192146786d792682ba51696f503c79625dd20f87bcf651f
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOB ENPP2 GABBR2 DST FRZB CNTNAP2 USH2A

3.40e-0619214675b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ASXL1 ENPP2 PARD3B UBE2B NDUFAF6 CHD6 MBD5

3.40e-061921467916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GABRB2 DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.40e-061921467d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRB2 EYA4 NEBL CSMD2 PTPRT SORCS1 PTPRD

3.76e-061951467787e95fb59c40bba784544b662fac37606ae1427
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid-Microglia|GW08 / Sample Type, Dataset, Time_group, and Cell type.

DOCK2 RHBDF2 DOCK8 SIGLEC14 CPED1 ANAPC2 APBB1IP

3.89e-06196146789a0ccd0684777927d99d5fc5b7c498f3f124250
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08-Myeloid|GW08 / Sample Type, Dataset, Time_group, and Cell type.

DOCK2 RHBDF2 DOCK8 SIGLEC14 CPED1 ANAPC2 APBB1IP

3.89e-06196146791a8c4798572d6c1f03cef5e8e5464ed0046c7cf
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 EYA4 CASR FAT1 OVOL1 EPHA2 FGFR2

4.02e-0619714671e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ENPP2 PARD3B DST PTPRD LPL CNTNAP2 MACF1

4.02e-0619714670034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ENPP2 PARD3B DST PTPRD LPL CNTNAP2 MACF1

4.02e-06197146711a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

NEBL MAOB ENPP2 DST LPL FRZB MACF1

4.16e-061981467e0e47cf65774191981840b22905b2094b95abe0f
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 CPED1 AFAP1 DST PTPRD LPL MACF1

4.30e-06199146730d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 MAOB AFAP1 DST PTPRD LPL MACF1

4.30e-061991467e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHD7 NUF2 SORCS1 DST LPL ASPM BCAR3

4.30e-0619914679940f347973bf976ee23fb4b1cf1f349d96c21df
ToppCellVE|World / Condition, Cell_class and T cell subcluster

H1-10 SAMD9 SMCHD1 SNX6 MACF1 AKAP13 APBB1IP

4.44e-0620014678ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 MAOB AFAP1 DST PTPRD LPL MACF1

4.44e-06200146744a68bacdb3d5bf563bd35952176995850933a81
ToppCellCOVID-19|World / Disease, condition lineage and cell class

H1-10 RBBP6 SMCHD1 KMT2C MACF1 AKAP13 DYNC1H1

4.44e-0620014677dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CHL1 MAOB AFAP1 DST PTPRD LPL MACF1

4.44e-062001467dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

CHL1 RAP1GAP2 GABBR2 CSMD2 PTPRT LPL FRZB

4.44e-0620014675c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EYA4 PARD3B FAT1 CRYGS CAPS2

7.50e-0682146542017b8ace6f142a8358213c95a2632226c3a867
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EYA4 PTPRT FAT1 CRYGS CNTNAP2 CAPS2

7.80e-06143146624fd24846fbef049af669a57d42fcc18928d2b27
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CHL1 KRT1 PTPRT FAT1 CNTNAP2 APBB1IP

1.11e-0515214668ff5a178a8f3550d89a003c0858820aab3773386
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

DOCK2 GRIA2 GABBR2 PTPRT CNTNAP2 USH2A

1.64e-05163146619c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B3 E2F7 NUF2 ATAD2 ACAN ASPM

1.76e-051651466eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellfacs-BAT-Fat-24m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ATP8B3 PDCL2 NEB CRYGS STX11

1.82e-051661466001a31aaa4ab4d5606b894faf6fcaad524405064
ToppCellfacs-BAT-Fat-24m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ATP8B3 PDCL2 NEB CRYGS STX11

1.82e-05166146631ed1290b4a977eabfc29674a5c593985bff6a74
ToppCellfacs-BAT-Fat-24m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 ATP8B3 PDCL2 NEB CRYGS STX11

1.82e-051661466c71ad3fc6a14507609d17756431d3deff9fda418
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP2 PDCL2 GABBR2 PTPRT TXNRD1 CNTNAP2

2.38e-051741466f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUF2 ATAD2 LPL ASPM BCAR3 APBB1IP

2.38e-05174146665147b0f8c2ccadd5685430d31081520c157536a
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHL1 GRIA2 CSMD2 HCN2 SORCS1 PPP1R3A

2.46e-0517514668362a46f5804333baa84cd56d450bc147f372a7e
ToppCellwk_15-18-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EYA4 ENPP2 GRIA2 ACAN FRZB FGFR2

2.46e-051751466a84965d28438a4228d841b357c2cd75cf4b59a63
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHL1 GRIA2 CSMD2 HCN2 SORCS1 PPP1R3A

2.46e-0517514668b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CHL1 DOCK8 ODAD2 NSUN7 DMRT2 KBTBD12

2.46e-0517514661d8da48236549c01381f777ce5b2937f9f86acc2
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA2 CIT VWDE SORCS1 PTPRD LPL

2.62e-0517714661dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIA2 CIT VWDE SORCS1 PTPRD LPL

2.62e-051771466426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

DOCK2 PLSCR5 DOCK8 SIGLEC5 CSMD2 AFAP1L1

2.79e-051791466cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

H1-10 E2F7 NUF2 ATAD2 CIT ASPM

2.79e-05179146654191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c14-MKI67-CCL5_h|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HCN3 E2F7 NUF2 CIT ACAN ASPM

2.88e-05180146642f48e646fc6e72ad3cce72409ace3a0b64020a2
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK2 RHBDF2 DOCK8 SIGLEC14 LILRB1 APBB1IP

2.97e-051811466090e89b506d945e123e647d08947e9649a65ce7c
ToppCellwk_15-18-Mesenchymal-Chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EYA4 ENPP2 GRIA2 ACAN FRZB FGFR2

2.97e-0518114668950844b3e65c7028d80da5787ae2ce509c3d52d
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYA4 NEBL CPED1 PPP1R3A LPL KBTBD12

2.97e-051811466719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT1 MAOB E2F7 VWDE FOXRED2 GALNT8

3.06e-0518214664cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

SAMD9 RBBP6 SMCHD1 KMT2C DST PLSCR1

3.16e-0518314668f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.25e-051841466371c1927ac06b77ff462a94cca6acb802f9724ff
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK8 SMCHD1 DHX9 ITSN2 DDX23 MACF1

3.25e-0518414661154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

EYA4 NEBL CPED1 DST LPL AKAP13

3.25e-051841466ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.25e-051841466fbac70333e4f028bfbdd9cc9401427caac9f0c47
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.25e-051841466dd6777a0cb49cd79fc439920c3c930a1e4681bb0
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 GRIA2 ACAN GALNT8 FRZB FGFR2

3.35e-0518514668ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

EYA4 NEBL CPED1 PPP1R3A LPL KBTBD12

3.35e-051851466549eeb521c3985bff396ea0f202db21822efa51f
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.35e-0518514666b832b3e080dfadd21253ac45022192f4d3cb37b
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHL1 GRIA2 ACAN GALNT8 FRZB FGFR2

3.35e-051851466b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.46e-051861466e41f14aee8cfbf76b8d0d4695a6170e2cd92aec8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CSMD2 CPED1 PPP1R3A FAT1 ACAN FRZB

3.46e-0518614664780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CASR CPED1 HOXA11 HOXD11 FRZB MMP1

3.46e-051861466360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.46e-051861466b3633cd4e360c5b45060c50b4f606d483e03a89a
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.46e-0518614669dd31dc9af1704f35c74de726a6c27fa21e9a014
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.56e-05187146623a42c172d5cc36cb8793c0bc2ce357c6c8e5d39
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.56e-0518714665ce7cf02990465b6f793205e4be07e8337b3570a
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.56e-05187146617a37fc3a1d62fef3137e5ff26a84c0b8c80e124
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.56e-0518714661b0eb29394040555516677b9de75c15e769c4c53
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.56e-05187146611c773cf3dc1e725b7e4d8edd676c8a94a231d2a
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GABRB2 GRIA2 NEB KCNB2 DMRT2 CNTNAP2

3.67e-0518814661f912ea015f50570e848259d948a0ba682d64bb4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.67e-05188146626c0a94951236a5d17a169920b0a8a9d0dd7d0ed
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.67e-051881466af300574c4e95505f56bf716bcee1e4777944e8e
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.67e-0518814665df5a0890e17d19f55770525345a656253696887
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.67e-051881466c65fb9a3c910dd6166853f4f3a2f2c2411ccf03b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.67e-051881466e169e9bb85892e52880ee949d0f691d0ea0c8dc9
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.67e-0518814669e923b0d79495ee1a3a097741a877f25d439eda3
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.67e-05188146614dbc985abc2012c9f53deb243d465e4175f419f
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.78e-051891466389ccb68acb82893709f256315111470cf4beed3
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ENPP2 ZNF248 STX11 RNF122 DYNC1H1 ANAPC4

3.78e-05189146699b01893da9f9f7c9528afaffad178285211738b
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

EYA4 PIKFYVE SACS ITSN2 LPXN BCAR3

3.78e-05189146611cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.78e-05189146658465b9407fbce91cca8f199950d6e0054c38fbc
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK8 ENPP2 PARD3B CHD7 FGFR2 APBB1IP

3.78e-05189146642ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.78e-051891466e9fe8d17f4b7cca9bbf3655047e27b2fec5060c1
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.78e-0518914667ac78441a15a82218deaafd47accff2ea5c8de20
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

EYA4 NEBL CPED1 FAT1 LPL AKAP13

3.89e-05190146693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK2 RHBDF2 DOCK8 CPED1 LILRB1 APBB1IP

3.89e-051901466d4f954e0748898df69e1710df558564db703dd61
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK2 E2F7 NUF2 ATAD2 CIT ASPM

4.01e-051911466bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

H1-10 E2F7 NUF2 ATAD2 CIT ASPM

4.01e-051911466b978afe76754cc56e1672abca27be289bb56375b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK8 ENPP2 PARD3B CHD7 FGFR2 APBB1IP

4.01e-051911466a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

CHL1 NEBL FAT1 EPHA2 SERPINB11 FGFR2

4.13e-05192146693b2ca0a97776d28c7e8f1a0642c4b63a5554aab
DiseaseColorectal Carcinoma

CHL1 EYA4 PSMA2 ABCB5 MSH2 KCNB2 PTPRT TXNRD1 KMT2C FAT1 PTPRD SACS ABCD3 DLG3 MMP1 ABCC2 ANAPC4

5.83e-0870214317C0009402
Diseaselung non-small cell carcinoma (is_implicated_in)

MSH2 KMT2C FAT1 XPO5 FRZB ABCC2 BAG6

5.42e-061391437DOID:3908 (is_implicated_in)
DiseaseColorectal Neoplasms

EYA4 ABCB5 MSH2 TXNRD1 FAT1 PTPRD ABCD3 MMP1 ABCC2

8.86e-062771439C0009404
DiseaseIntellectual Disability

CHL1 GABRB2 DOCK8 RNF113A GRIA2 CHD3 KMT2C SACS MACF1 FGFR2 DYNC1H1

1.23e-0544714311C3714756
Diseasecongenital heart disease (implicated_via_orthology)

CHD7 KMT2C UBE2A UBE2B CHD6

2.18e-05691435DOID:1682 (implicated_via_orthology)
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

MSH2 PTPRT KMT2C FAT1

6.75e-05451434DOID:3748 (is_implicated_in)
DiseaseLimb Deformities, Congenital

HOXA11 HOXD11 FGFR2

7.21e-05171433C0206762
Diseasephotoreceptor cell layer thickness measurement

CHD7 NPLOC4 AFAP1L1 DST FGFR2 BBOF1

8.73e-051481436EFO_0803370
Diseasecomplement factor H-related protein 3 measurement

RAP1GAP2 PTPRT SORCS1 ACAN ASPM USH2A

1.81e-041691436EFO_0600056
Diseaseresponse to TNF antagonist, joint damage measurement

NEBL GABBR2 PRORP

2.37e-04251433EFO_0004653, EFO_0005413
Diseasebody surface area

EYA4 ENPP2 SMCHD1 E2F7 KCNB2 CPED1 HIF1AN ACAN ITSN2 MACF1 AKAP13

3.11e-0464314311EFO_0022196
Diseasegout

FAT1 OVOL1 DST PTPRD CNTNAP2 FGFR2

4.00e-041961436EFO_0004274
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD7 CHD6

4.82e-0471432DOID:0050834 (implicated_via_orthology)
Diseasedegenerative disc disease (implicated_via_orthology)

ACAN MMP1

4.82e-0471432DOID:90 (implicated_via_orthology)
Diseaseurinary bladder cancer (is_implicated_in)

NAT2 MSH2 FGFR2 MMP1

5.18e-04761434DOID:11054 (is_implicated_in)
Diseasevisual epilepsy (implicated_via_orthology)

CIT CNTNAP2 ABCC2

5.97e-04341433DOID:11832 (implicated_via_orthology)
Diseasecoronary aneurysm

DOCK2 NEBL CSMD2

6.51e-04351433EFO_1000881
Diseasenon-alcoholic fatty liver disease (implicated_via_orthology)

UBE2A UBE2B LPL

7.08e-04361433DOID:0080208 (implicated_via_orthology)
Diseaseaplastic anemia (is_marker_for)

ANAPC2 CD40LG

8.21e-0491432DOID:12449 (is_marker_for)
DiseaseProstatic Neoplasms

NAT2 SAMD9 CHD3 CHD7 KMT2C LPL ITSN2 AKAP13 CHD6 MGA

8.73e-0461614310C0033578
DiseaseMalignant neoplasm of prostate

NAT2 SAMD9 CHD3 CHD7 KMT2C LPL ITSN2 AKAP13 CHD6 MGA

8.73e-0461614310C0376358
Diseasedolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 measurement

SIGLEC14 SIGLEC5

1.02e-03101432EFO_0801544
Diseasehydroxyproline measurement

PTPRT SORCS1

1.02e-03101432EFO_0010498
DiseaseNeurodevelopmental Disorders

GABRB2 DOCK8 PARD3B KMT2C

1.11e-03931434C1535926
Diseasedilated cardiomyopathy (is_implicated_in)

EYA4 NEBL MMP1

1.19e-03431433DOID:12930 (is_implicated_in)
Diseaseretinal nerve fibre layer thickness measurement

NPLOC4 PTPRD BBOF1

1.19e-03431433EFO_0600004
Diseasevisual epilepsy (is_implicated_in)

CNTNAP2 ASPM

1.25e-03111432DOID:11832 (is_implicated_in)
DiseaseLiver Cirrhosis, Experimental

ENPP2 SIGLEC5 SLC25A30 FAT1 PTPRD LPL LPXN MMP1 ABCC2 PLSCR1 APBB1IP

1.42e-0377414311C0023893
DiseaseAdenoid Cystic Carcinoma

KMT2C FAT1 ASPM MGA

1.45e-031001434C0010606
Diseasesialic acid-binding Ig-like lectin 14 measurement

SIGLEC14 SIGLEC5

1.49e-03121432EFO_0008284
Diseaseperiodontitis (is_marker_for)

CD40LG MMP1

1.49e-03121432DOID:824 (is_marker_for)
DiseaseAlzheimer's disease (is_marker_for)

NDUFA5 LPL CD40LG HADHA DYNC1H1 CDK7

1.63e-032571436DOID:10652 (is_marker_for)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRB2 PARD3B DLG3

1.74e-03491433DOID:0060037 (implicated_via_orthology)
DiseaseMuscular Dystrophy, Facioscapulohumeral

SMCHD1 ACAN

1.76e-03131432C0238288
Diseasenon-alcoholic fatty liver disease

PTPRD EPHA2 LPL CNTNAP2 NDUFAF6

1.98e-031821435EFO_0003095
DiseaseMalignant neoplasm of breast

NAT2 APCS MAGOHB OLA1 SORCS1 PPP1R3A PTPRD HOXD11 ITSN2 MACF1 FGFR2 MMP1 BCAR3

2.24e-03107414313C0006142
Diseaselow density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor

APCS CSMD2

2.35e-03151432EFO_0004611, EFO_0005658
Diseasesphingomyelin measurement

KRT1 NVL CASR LPL USH2A DYNC1H1

2.41e-032781436EFO_0010118
Diseasesyndromic intellectual disability (implicated_via_orthology)

UBE2A UBE2B

2.68e-03161432DOID:0050888 (implicated_via_orthology)
Diseasecentral nervous system disease (implicated_via_orthology)

GEMIN5 GRIA2

2.68e-03161432DOID:331 (implicated_via_orthology)
Diseaseautism spectrum disorder (is_implicated_in)

CNTNAP2 MBD5

2.68e-03161432DOID:0060041 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

MSH2 PTPRT FAT1 XPO5

2.90e-031211434DOID:9256 (is_implicated_in)
Diseasepartial epilepsy

TBC1D32 PTPRD

3.02e-03171432EFO_0004263
Diseasepost-traumatic stress disorder

GABRB2 KCNB2 GABBR2 VWDE ANAPC4

3.10e-032021435EFO_0001358
Diseaseretinal layer thickness measurement

NPLOC4 PTPRD BBOF1

3.12e-03601433EFO_0600002
Diseaseplatelet-derived growth factor BB measurement

DOCK2 PLSCR5 RNF122

3.27e-03611433EFO_0008264
DiseaseMalignant neoplasm of endometrium

MSH2 FGFR2

3.39e-03181432C0007103
DiseaseCarcinoma in situ of endometrium

MSH2 FGFR2

3.39e-03181432C0346191
Diseaseage at menopause

H1-10 GEMIN5 CHD7 CHD6 MGA DYNC1H1

3.63e-033021436EFO_0004704
Diseaseresponse to mitochondrial complex I inhibitor

GABBR2 TXNRD1

3.78e-03191432EFO_0600033
DiseaseCoronary Arteriosclerosis

NAT2 APCS CD40LG

3.91e-03651433C0010054
DiseaseCoronary Artery Disease

NAT2 APCS CD40LG

3.91e-03651433C1956346
Diseaseatherosclerosis (biomarker_via_orthology)

CASR CD40LG

4.18e-03201432DOID:1936 (biomarker_via_orthology)
Diseasetype 2 diabetes mellitus (is_marker_for)

LPL FRZB CD40LG MMP1

4.40e-031361434DOID:9352 (is_marker_for)
Diseaselifestyle measurement, anxiety disorder measurement

CSMD2 NPLOC4 SORCS1 USH2A

4.52e-031371434EFO_0007795, EFO_0010724
DiseaseProfound Mental Retardation

CHL1 DOCK8 FGFR2 DYNC1H1

4.75e-031391434C0020796
DiseaseMental Retardation, Psychosocial

CHL1 DOCK8 FGFR2 DYNC1H1

4.75e-031391434C0025363
DiseaseMental deficiency

CHL1 DOCK8 FGFR2 DYNC1H1

4.75e-031391434C0917816

Protein segments in the cluster

PeptideGeneStartEntry
DLYNRKGKYFNVERV

ANAPC4

461

Q9UJX5
QGYLQKKVRDQQLVY

ANAPC2

796

Q9UJX6
ENYLTEKGNERNVKF

CFAP97

61

Q9P2B7
QRGFSAQYQVKKQIE

CSMD2

296

Q7Z408
TEIKEGYKQYSQRNA

CAPS2

141

Q9BXY5
GYKQYSQRNAENTKS

CAPS2

146

Q9BXY5
EKDKGLQTTQNGRFY

CALR3

61

Q96L12
ESKAYQKINNERRTY

CCDC169

136

A6NNP5
ENGKQLTVKRQGLYY

CD40LG

156

P29965
RLYRSDVFKGENYQK

CPED1

426

A4D0V7
RNKQKTFYYLGQELQ

TBC1D32

411

Q96NH3
YQGRVLQDDKKLQEY

BAG6

61

P46379
KGAQVNQTERYEKFN

BCAR3

791

O75815
LQRYTQNLKDAKDFG

ABCB5

266

Q2M3G0
GAVFYNKERTRNIVK

ADGRL1

221

O94910
YNVYAKKGERLFINE

CASR

511

P41180
AQYKYGKNRVEADAK

AFAP1

551

Q8N556
KTLYDNYQRAVAKAG

APBB1IP

421

Q7Z5R6
EREELQQKKGTYQYD

AKAP13

2636

Q12802
QQKKGTYQYDLERLR

AKAP13

2641

Q12802
ANNRAYNGQFKEKVI

ATP8B3

111

O60423
GEEENQKRYYLRQRK

ATAD2

286

Q6PL18
AGRNVFKENDYLQKA

BBOF1

221

Q8ND07
EYKNNNKLREYQLEG

CHD7

961

Q9P2D1
ELRQQKFYLETQAGK

CIT

811

O14578
IQSAFRGYNKRVKYQ

ASPM

1831

Q8IZT6
EGKGIYNNIKNFVRF

ATP2C1

691

P98194
RRNLYKKQESEQAGV

ASXL1

421

Q8IXJ9
ERSDYYNQLKQKGVK

CCDC27

621

Q2M243
VTFEDKRKANYERGN

ITSN2

361

Q9NZM3
AVKAAGKYRQQGRNY

OLA1

361

Q9NTK5
AGFVDNKLKQRVIQY

NVL

6

O15381
RTEVQSVQYGKEKAN

PTPN4

336

P29074
GDLAYRRQEYQKALQ

C8orf76

61

Q96K31
GRTYTLRNQKVKYVD

MAOB

41

P27338
GNSYVKYRLTENENK

FAT1

3836

Q14517
GLARDINNIDYYKKT

FGFR2

646

P21802
INNIDYYKKTTNGRL

FGFR2

651

P21802
GSTDRIQKLRKEYYQ

PARD3B

1021

Q8TEW8
NRKEKLYESQNRGVY

KMT2C

4811

Q8NEZ4
KIENVSYQDKGNYRC

CHL1

296

O00533
RYLLRYKSDSDKQQG

IGLV5-39

66

A0A0G2JS06
DYKDVNEEYGARNRK

MGA

2061

Q8IWI9
DEQQNFFAQIKGYKR

HIF1AN

201

Q9NWT6
CAKRFQVEQIGDNKY

DST

7291

Q03001
DQQNGRTYLKYSIKA

H1-10

81

Q92522
ANFEYIIAEKRGKNN

ECHS1

31

P30084
KFDQNGKRINYTINI

GRIA2

361

P42262
KQKFGELREISGNQY

PDCL2

86

Q8N4E4
NNKYEIKNSFGQRVY

PLSCR1

126

O15162
NKYEIKNSLGQRIYF

PLSCR5

86

A0PG75
YRNKYEDEINKRTNA

KRT1

266

P04264
NNLGYEINKVRAKRS

LPL

311

P06858
KNARQEVVEKYEIYG

NUF2

266

Q9BZD4
REGYNKAVYISVQDK

PBDC1

151

Q9BVG4
KAYRNIKELENYAEN

NDUFAF6

166

Q330K2
DQYLSKQDGKIYRSR

NPLOC4

111

Q8TAT6
QLSKGIFREQNDKTY

LPXN

361

O60711
FYKDIKQNGTQYRSL

GABRB2

361

P47870
SKGKIQFNNYQVRYR

ABCC2

1296

Q92887
EKKINRDRLQYYSAN

HOXA11

296

P31270
GIDLKQQKREQSRFY

DDX23

306

Q9BUQ8
INKRYTGKANAEFNL

FOXRED2

81

Q8IWF2
QSLDSSRRQYQEKYK

HCN3

351

Q9P1Z3
GKEDDKIYRGINNYQ

RNF113A

146

O15541
AKRFQVEQIGENKYR

MACF1

7136

Q9UPN3
IHGVQQKYAYKERRA

OVOL1

196

O14753
ARTFGQKKDRYEINS

ACAN

2456

P16112
RQAVNNFKNETGYTK

RBBP6

316

Q7Z6E9
TAKEDENRNKNRYGN

PTPRT

906

O14522
ENRNKNRYGNIISYD

PTPRT

911

O14522
RIYLGVNEKQRKNFQ

PPP1R3A

521

Q16821
VYRIGYKNSQNNTEK

PIKFYVE

1916

Q9Y2I7
RRVKELYNTYKNNVG

EYA4

486

O95677
QGQTNDAKFKEIRYR

SLC25A30

36

Q5SVS4
IVNNFSEFYKEQKRQ

KCNB2

416

Q92953
VYRQKIEDNSQGKAF

E2F7

451

Q96AV8
LQGDFDKYNKTTQRN

DOCK2

431

Q92608
TADQREYQQELKKNY

DOCK8

2036

Q8NF50
SGKQNNFERKAVYQR

DMRT2

181

Q9Y5R5
YSCRQYQKARENVKG

CPLANE1

1291

Q9H799
EEGYENAIRDYNKKQ

DNAH17

1716

Q9UFH2
DKDRNVKYYQGIRAA

PRMT7

41

Q9NVM4
KSREYKNSNQLREYQ

CHD6

451

Q8TD26
GQFATVYKARDKNTN

CDK7

21

P50613
NQSKFFRVLNGYKID

CHD3

891

Q12873
TKITFYEDKNFQGRR

CRYGS

6

P22914
QQKAAQDLFRKFGYN

GALNT8

136

Q9NY28
VTYRKKGDSNSYNVR

EPHA2

471

P29317
EKKLNRDRLQYFTGN

HOXD11

321

P31277
AYYVQQARKEKNKDN

CTR9

91

Q6PD62
RRQTYEQANKIYDKA

DLG3

756

Q92796
GDKILEENFRYNNYK

MBD5

1256

Q9P267
YFERIGYKNSRNKLD

NAT2

6

P11245
FYIYQEGVKRKDLNS

HADHA

636

P40939
SGKTPQQYEREYNNK

GABBR2

331

O75899
KQFEKQVELYRNGQR

DYNC1H1

1181

Q14204
QYVKRYKGHRNNDTI

DCAF8L1

426

A6NGE4
NYNGVNITDLARRKK

CNTNAP2

341

Q9UHC6
QRSYEGKEFQRNLKT

FAM186A

1021

A6NE01
NKYKNNFRELFETVG

SACS

2376

Q9NZJ4
SSRRQYQEKYKQVEQ

HCN2

471

Q9UL51
RQYRVEVYKNRAGNK

MSH2

96

P43246
FQRVLVKKYASERNG

ENPP2

716

Q13822
RGANLKDYYSRKEEQ

DHX9

141

Q08211
YKNGSSEKREVRQFQ

PTPRD

1501

P23468
SRQKNKNVEIYRYHD

KBTBD12

346

Q3ZCT8
DGKLRYANNSNYKND

MAGOHB

31

Q96A72
VQNGKITKYLVRYDN

USH2A

4381

O75445
VNNTFKFGVIYQKAR

RAP1GAP2

256

Q684P5
EKNKEAIYSGYIRNR

SMCHD1

276

A6NHR9
NVKYNNDKSRDYTRP

PTBP2

261

Q9UKA9
YEFGKAFFQKQNVRR

SLC25A40

321

Q8TBP6
GGQETQEYRLYREKK

LILRB1

51

Q8NHL6
QYLLRYKSDSDKQQG

IGLV5-45

66

A0A087WSX0
YYNLKNDGRQVEKRR

MMP1

41

P03956
YYNQGETRKKELLQS

PIGL

81

Q9Y2B2
QNEEAKTRRKVAGYF

SAMD9

1286

Q5K651
EEVYNNLKRRGYNKV

NSUN7

216

Q8NE18
DVNYERKGSIYKNLV

ODAD2

281

Q5T2S8
ERGRDVKYSYQQNKL

SIGLEC5

121

O15389
IIYFKGQRQNKFQVR

SERPINB11

181

Q96P15
NAAYRKYTEQITNEK

NDUFA5

41

Q16718
RYLRKDEGSNKQVYS

PRORP

66

O15091
SEEIAFYNGNKREKQ

ABCD3

276

P28288
EKCQRENGFIYFQKI

BROX

321

Q5VW32
NQYKYGKNRAEEDAR

AFAP1L1

606

Q8TED9
KYQREYNKNERNDLS

C12orf40

376

Q86WS4
REKKVVYENAYGQFI

TXNRD1

271

Q16881
QGQSIDARFKEIKYR

SLC25A14

71

O95258
DSLQYLANKKYTQGR

VWDE

721

Q8N2E2
SKLRNQAQSERYGYK

RNF122

61

Q9H9V4
YNTQGRDNELLVYKE

APCS

71

P02743
VNRLYKENEENQKSY

RNF34

296

Q969K3
KEVQRFGQNYKRIFI

SAGE2P

541

A6NJ88
FRNNYNYVIRAKVKE

FRZB

191

Q92765
TGQAKAQVRKAVQYE

STX11

256

O75558
KAGLFSQEQYERNKS

TMEM40

36

Q8WWA1
AQELLQKYGNTKTYR

GEMIN5

1486

Q8TEQ6
AAQLYQENKREYEKR

UBE2A

126

P49459
SNQFKNYERQKVFLE

XPO5

656

Q9HAV4
NYVNGKTFLEKRYNE

PSMA2

166

P25787
DYRKIKSQNRNGEFE

PRPF38A

126

Q8NAV1
FLEYNQDLSVRGKNK

SNX6

166

Q9UNH7
QNFYRDVLQKKNGLS

ZNF205

146

O95201
DNQVKTFITYNKGRD

SORCS1

486

Q8WY21
RNKGVYESVKYIQQE

RHBDF2

441

Q6PJF5
RDNKVYCKGRENEQF

TCHH

1236

Q07283
ERGRDVKYSYQQNKL

SIGLEC14

121

Q08ET2
AAQLYQENKREYEKR

UBE2B

126

P63146
GEKSYKYDQKRNAIN

ZNF248

186

Q8NDW4
RAKENQKNISNVYYR

NEBL

706

O76041
VAKNQSDRLYKENYE

NEB

626

P20929
TAGDQISQIKYRKNY

NEB

5431

P20929