Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentlateral element

SYCP2 SMC3

2.51e-0419262GO:0000800
DomainBromodomain_CS

TAF1 BRWD1

5.48e-0426252IPR018359
DomainBROMODOMAIN_1

TAF1 BRWD1

1.11e-0337252PS00633
DomainBromodomain

TAF1 BRWD1

1.17e-0338252PF00439
DomainBROMODOMAIN_2

TAF1 BRWD1

1.37e-0341252PS50014
DomainBROMO

TAF1 BRWD1

1.43e-0342252SM00297
DomainBromodomain

TAF1 BRWD1

1.43e-0342252IPR001487
Domain-

TAF1 BRWD1

1.43e-03422521.20.920.10
DomainZF_RING_1

ZSWIM2 TRAF4 RNF217

6.68e-03291253PS00518
DomainZF_RING_2

ZSWIM2 TRAF4 RNF217

7.13e-03298253PS50089
Pubmed

FOXM1 regulates expression of eukaryotic elongation factor 2 kinase and promotes proliferation, invasion and tumorgenesis of human triple negative breast cancer cells.

FOXM1 EEF2K

6.25e-07228226918606
Pubmed

SYCP2 and SYCP3 are required for cohesin core integrity at diplotene but not for centromere cohesion at the first meiotic division.

SYCP2 SMC3

1.31e-05728215870106
Pubmed

Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

EEF2K RPS6KA5

3.42e-051128211500364
Pubmed

A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.

SYCP2 SMC3

4.10e-051228221274006
Pubmed

Meiotic cohesin complexes are essential for the formation of the axial element in mice.

SYCP2 SMC3

4.10e-051228222711701
Pubmed

Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis.

SYCP2 SMC3

5.65e-051428222346761
Pubmed

STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis.

SYCP2 SMC3

1.18e-042028224797475
Pubmed

Meiosis in mice without a synaptonemal complex.

SYCP2 SMC3

1.43e-042228222164254
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ANKRD17 ZKSCAN2 TAF1 SENP7 BRWD1 INO80E

2.21e-04111628631753913
Pubmed

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

FOXM1 ZSWIM2

3.25e-043328230783098
Pubmed

A human MAP kinase interactome.

ANKRD17 TAF1 RPS6KA5 SMC3

5.91e-0448628420936779
Pubmed

Congenital Diaphragmatic Hernia Overview

SMC3 HES7

6.33e-044628220301533
Pubmed

Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.

FOXM1 TRAF4 SMC3

7.87e-0422628331452512
CytobandEnsembl 112 genes in cytogenetic band chr2q14

AMMECR1L NT5DC4

4.56e-03165282chr2q14
CytobandEnsembl 112 genes in cytogenetic band chr16p12

EEF2K ZKSCAN2

4.95e-03172282chr16p12
GeneFamilyRing finger proteins

TRAF4 RNF217

3.00e-0227518258
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 HHIP RNF217 PGF

5.36e-06186284aa88d9573a237b2b8e6025fee31f69fbce824497
ToppCellfacs-Lung-EPCAM-18m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 HHIP RNF217 PGF

5.36e-06186284ecc5acd111a6ee50d59544d1bdd7ed94e2812aae
Diseasepeak expiratory flow

PAQR8 HHIP ZKSCAN2 NCMAP

8.92e-04498264EFO_0009718
Diseaselung adenocarcinoma (is_marker_for)

EEF2K TRAF4

2.55e-0385262DOID:3910 (is_marker_for)
DiseaseAdenocarcinoma of large intestine

EEF2K TAF1

3.24e-0396262C1319315
Diseasealpha fetoprotein measurement

ANKRD17 SENP7

3.50e-03100262EFO_0010583

Protein segments in the cluster

PeptideGeneStartEntry
MGKRRCVPPLEPKLA

AMMECR1L

1

Q6DCA0
PRGMVRVCDLLLKKK

ANKRD17

51

O75179
CRLFIGGIPKMKKRE

RBM47

151

A0AV96
RRPMLPLEAQKKKDC

EXO5

201

Q9H790
DLLRKGPVMEVPCDK

CAMKK1

231

Q8N5S9
CPRERLKGMLKEIKP

HMGN2P46

71

Q86SG4
QRLLMKDPKKRLGCG

RPS6KA5

291

O75582
RKMRTRRELEPKGPK

NCMAP

56

Q5T1S8
EKRPRLPRKLKMAVG

INO80E

161

Q8NBZ0
RLPKILEDGLPKMPC

PAQR8

21

Q8TEZ7
KKDPRLPILLGKMKE

NT5DC4

196

Q86YG4
LKAKMVPEKVPRRCA

BRWD1

2221

Q9NSI6
KTELPLGARRKMKPL

FOXM1

356

Q08050
QMCIIELKDRPGKPL

EEF2K

211

O00418
DGPKMLKPLVEKRRR

HES7

11

Q9BYE0
GPARRLSIKMKKLPE

SYDE1

161

Q6ZW31
PKKMCKRPCILILDS

SENP7

926

Q9BQF6
KEECMKKIRELGSLP

SMC3

936

Q9UQE7
PKKMKERPDLKLKCG

TAF1

1251

P21675
LMCRVCLEDKPIKPL

RNF217

261

Q8TC41
KIVDPKRPLMPEECR

HHIP

581

Q96QV1
QRKPLREKMKPERCG

PGF

201

P49763
KKMDKTIPEGRIRLP

SYCP2

1001

Q9BX26
RKLKPMDPRRKVCHL

MYCBPAP

96

Q8TBZ2
KPKRRLLCPLCGKPM

TRAF4

11

Q9BUZ4
MLKCPLCRKEFAPLK

ZSWIM2

191

Q8NEG5
DKPKEMIPVPRLKRI

ZKSCAN2

436

Q63HK3
PKRIRKAAKRELMPC

ZNF692

316

Q9BU19