Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone acetyltransferase activity	KAT6B BRPF1 KAT6A	4.40e-05	51	27	3	GO:0004402
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	KAT6B BRPF1 KAT6A	5.52e-05	55	27	3	GO:0061733
GeneOntologyMolecularFunction	histone H3K14 acetyltransferase activity	KAT6B KAT6A	6.30e-05	9	27	2	GO:0036408
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	KAT6B BRPF1 KAT6A	7.17e-05	60	27	3	GO:0034212
GeneOntologyMolecularFunction	retromer complex binding	WASHC2C WASHC2A	7.87e-05	10	27	2	GO:1905394
GeneOntologyMolecularFunction	histone H4K8 acetyltransferase activity	BRPF1 KAT6A	9.61e-05	11	27	2	GO:0043996
GeneOntologyMolecularFunction	histone H4K5 acetyltransferase activity	BRPF1 KAT6A	9.61e-05	11	27	2	GO:0043995
GeneOntologyMolecularFunction	histone H4K12 acetyltransferase activity	BRPF1 KAT6A	1.15e-04	12	27	2	GO:0043997
GeneOntologyMolecularFunction	N-acetyltransferase activity	KAT6B BRPF1 KAT6A	1.57e-04	78	27	3	GO:0008080
GeneOntologyMolecularFunction	ubiquitin-ubiquitin ligase activity	STUB1 UBR5	1.59e-04	14	27	2	GO:0034450
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	KAT6B KAT6A	1.83e-04	15	27	2	GO:0010484
GeneOntologyMolecularFunction	N-acyltransferase activity	KAT6B BRPF1 KAT6A	3.46e-04	102	27	3	GO:0016410
GeneOntologyMolecularFunction	acetyltransferase activity	KAT6B BRPF1 KAT6A	3.67e-04	104	27	3	GO:0016407
GeneOntologyMolecularFunction	histone H4 acetyltransferase activity	BRPF1 KAT6A	4.38e-04	23	27	2	GO:0010485
GeneOntologyMolecularFunction	phosphatidylinositol-5-phosphate binding	WASHC2C WASHC2A	4.38e-04	23	27	2	GO:0010314
GeneOntologyMolecularFunction	phosphatidylinositol-3,5-bisphosphate binding	WASHC2C WASHC2A	7.99e-04	31	27	2	GO:0080025
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	WASHC2C WASHC2A	1.02e-03	35	27	2	GO:0043325
GeneOntologyMolecularFunction	phosphatidylinositol-4-phosphate binding	WASHC2C WASHC2A	1.08e-03	36	27	2	GO:0070273
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1H CACHD1	1.76e-03	46	27	2	GO:0005245
GeneOntologyMolecularFunction	phosphatidylinositol-3-phosphate binding	WASHC2C WASHC2A	1.91e-03	48	27	2	GO:0032266
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	WASHC2C WASHC2A	1.99e-03	49	27	2	GO:0005547
GeneOntologyMolecularFunction	acyltransferase activity	STUB1 KAT6B UBR5 BRPF1 KAT6A	3.45e-03	775	27	5	GO:0016746
GeneOntologyMolecularFunction	histone modifying activity	KAT6B BRPF1 KAT6A	3.55e-03	229	27	3	GO:0140993
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	KAT6B BRPF1 KAT6A	3.96e-03	238	27	3	GO:0016747
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate binding	WASHC2C WASHC2A	7.28e-03	95	27	2	GO:0005546
GeneOntologyCellularComponent	MOZ/MORF histone acetyltransferase complex	KAT6B BRPF1 KAT6A	5.96e-08	7	26	3	GO:0070776
GeneOntologyCellularComponent	H3 histone acetyltransferase complex	KAT6B BRPF1 KAT6A	9.53e-08	8	26	3	GO:0070775
GeneOntologyCellularComponent	WASH complex	WASHC2C WASHC2A	1.55e-04	15	26	2	GO:0071203
GeneOntologyCellularComponent	histone acetyltransferase complex	KAT6B BRPF1 KAT6A	2.12e-04	94	26	3	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	KAT6B BRPF1 KAT6A	2.86e-04	104	26	3	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	KAT6B BRPF1 KAT6A	3.29e-04	109	26	3	GO:1902493
GeneOntologyCellularComponent	transferase complex	ZNFX1 LEO1 STUB1 KAT6B BRPF1 KAT6A	9.80e-04	963	26	6	GO:1990234
GeneOntologyCellularComponent	intracellular protein-containing complex	ZNFX1 LEO1 STUB1 KAT6B BRPF1 KAT6A	1.03e-03	972	26	6	GO:0140535
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1H CACHD1	1.49e-03	46	26	2	GO:0005891
GeneOntologyCellularComponent	calcium channel complex	CACNA1H CACHD1	3.70e-03	73	26	2	GO:0034704
Domain	FAM21	WASHC2C WASHC2A	2.01e-06	2	27	2	IPR027308
Domain	FAM21/CAPZIP	WASHC2C WASHC2A	6.03e-06	3	27	2	IPR029341
Domain	CAP-ZIP_m	WASHC2C WASHC2A	6.03e-06	3	27	2	PF15255
Domain	MOZ_SAS	KAT6B KAT6A	2.01e-05	5	27	2	PF01853
Domain	HAT_MYST-type	KAT6B KAT6A	2.01e-05	5	27	2	IPR002717
Domain	MYST_HAT	KAT6B KAT6A	2.01e-05	5	27	2	PS51726
Domain	H15	KAT6B KAT6A	1.55e-04	13	27	2	SM00526
Domain	H15	KAT6B KAT6A	1.55e-04	13	27	2	PS51504
Domain	Histone_H1/H5_H15	KAT6B KAT6A	1.81e-04	14	27	2	IPR005818
Domain	Znf_PHD-finger	KAT6B BRPF1 KAT6A	1.98e-04	79	27	3	IPR019787
Domain	PHD	KAT6B BRPF1 KAT6A	2.82e-04	89	27	3	SM00249
Domain	Znf_PHD	KAT6B BRPF1 KAT6A	3.01e-04	91	27	3	IPR001965
Domain	ZF_PHD_2	KAT6B BRPF1 KAT6A	3.41e-04	95	27	3	PS50016
Domain	ZF_PHD_1	KAT6B BRPF1 KAT6A	3.52e-04	96	27	3	PS01359
Domain	Znf_FYVE_PHD	KAT6B BRPF1 KAT6A	1.22e-03	147	27	3	IPR011011
Domain	-	KAT6B KAT6A	1.52e-03	40	27	2	3.40.630.30
Domain	Acyl_CoA_acyltransferase	KAT6B KAT6A	1.92e-03	45	27	2	IPR016181
Domain	-	STUB1 KAT6B BRPF1 KAT6A	3.73e-03	449	27	4	3.30.40.10
Domain	Znf_RING/FYVE/PHD	STUB1 KAT6B BRPF1 KAT6A	4.04e-03	459	27	4	IPR013083
Domain	PHD	KAT6B KAT6A	5.23e-03	75	27	2	PF00628
Pathway	REACTOME_HATS_ACETYLATE_HISTONES	KAT6B BRPF1 KAT6A	2.14e-05	46	17	3	MM14935
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION	BRPF1 KAT6A	5.45e-04	29	17	2	MM15340
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ACETYLATION	BRPF1 KAT6A	5.84e-04	30	17	2	M27637
Pathway	REACTOME_HATS_ACETYLATE_HISTONES	KAT6B BRPF1 KAT6A	6.14e-04	142	17	3	M27233
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	KAT6B BRPF1 KAT6A	1.13e-03	175	17	3	MM14941
Pubmed	Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.	KAT6B BRPF1 KAT6A	1.46e-08	7	27	3	18794358
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NOL4L WASHC2C LMNA LEO1 STUB1 KAT6B DNMBP BRPF1	8.86e-08	774	27	8	15302935
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	FNBP1L WASHC2C LEO1 STUB1 DNMBP WASHC2A UBR5	2.52e-07	588	27	7	38580884
Pubmed	Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).	WASHC2C WASHC2A	5.80e-07	2	27	2	20827171
Pubmed	FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.	WASHC2C WASHC2A	5.80e-07	2	27	2	36717248
Pubmed	Tuba stimulates intracellular N-WASP-dependent actin assembly.	FNBP1L DNMBP	5.80e-07	2	27	2	16757518
Pubmed	Identification of a novel Rev-interacting cellular protein.	WASHC2C WASHC2A	5.80e-07	2	27	2	15847701
Pubmed	ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B.	KAT6B KAT6A	5.80e-07	2	27	2	39505971
Pubmed	The multidomain protein Brpf1 binds histones and is required for Hox gene expression and segmental identity.	BRPF1 KAT6A	5.80e-07	2	27	2	18469222
Pubmed	Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos.	BRPF1 KAT6A	5.80e-07	2	27	2	24646517
Pubmed	Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease.	KAT6B KAT6A	5.80e-07	2	27	2	27185879
Pubmed	The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.	KAT6B KAT6A	5.80e-07	2	27	2	24150941
Pubmed	MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.	KAT6B KAT6A	1.74e-06	3	27	2	36754959
Pubmed	Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin.	KAT6B KAT6A	1.74e-06	3	27	2	23063713
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	WASHC2C STUB1 DNMBP WASHC2A UBR5 BRPF1 PDCL3	3.01e-06	853	27	7	28718761
Pubmed	Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF).	KAT6B KAT6A	3.48e-06	4	27	2	21880731
Pubmed	The interaction of ETV6 (TEL) and TIP60 requires a functional histone acetyltransferase domain in TIP60.	KAT6B KAT6A	3.48e-06	4	27	2	17980166
Pubmed	Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.	BRPF1 KAT6A	3.48e-06	4	27	2	24258712
Pubmed	The chromatin regulator Brpf1 regulates embryo development and cell proliferation.	KAT6B BRPF1 KAT6A	4.04e-06	40	27	3	25773539
Pubmed	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.	KAT6B BRPF1 KAT6A	4.69e-06	42	27	3	16387653
Pubmed	Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.	KAT6B KAT6A	5.80e-06	5	27	2	17182677
Pubmed	MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.	KAT6B KAT6A	5.80e-06	5	27	2	11965546
Pubmed	Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.	STUB1 UBR5	8.69e-06	6	27	2	25594175
Pubmed	Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest.	BRPF1 KAT6A	8.69e-06	6	27	2	19001415
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	FAM171A1 ZNF131 DMXL2 TYW1 LMNA STUB1 WASHC2A UBR5	1.17e-05	1487	27	8	33957083
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CACNA1H ARRDC3 WASHC2C WASHC2A UBR5	1.40e-05	407	27	5	12693553
Pubmed	A FAM21-containing WASH complex regulates retromer-dependent sorting.	WASHC2C WASHC2A	1.62e-05	8	27	2	19922874
Pubmed	The E3 Ubiquitin Ligase SYVN1 Ubiquitinates Atlastins to Remodel the Endoplasmic Reticulum Network.	STUB1 ATL2	2.08e-05	9	27	2	32916628
Pubmed	Acetylation of HIV-1 integrase by p300 regulates viral integration.	KAT6B KAT6A	3.18e-05	11	27	2	16096645
Pubmed	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.	WASHC2C WASHC2A	3.81e-05	12	27	2	19922875
Pubmed	Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour.	WASHC2C WASHC2A	3.81e-05	12	27	2	27390154
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	FAM171A1 DMXL2 TYW1 WASHC2C WASHC2A	3.89e-05	504	27	5	34432599
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	STUB1 UBR5	5.25e-05	14	27	2	27626314
Pubmed	The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors.	BRPF1 KAT6A	5.25e-05	14	27	2	25757017
Pubmed	Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.	WASHC2C WASHC2A	6.06e-05	15	27	2	28892079
Pubmed	Placentation defects are highly prevalent in embryonic lethal mouse mutants.	DMXL2 WASHC2C WASHC2A	7.01e-05	103	27	3	29539633
Pubmed	COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A.	WASHC2C WASHC2A	9.84e-05	19	27	2	25355947
Pubmed	Ubiquitin-specific protease 7 sustains DNA damage response and promotes cervical carcinogenesis.	LMNA UBR5	1.21e-04	21	27	2	30179224
Pubmed	Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6.	STUB1 UBR5	1.33e-04	22	27	2	24981174
Pubmed	Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.	WASHC2C WASHC2A	1.45e-04	23	27	2	31748650
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	NOL4 STUB1 KAT6B UBR5 BRPF1 KAT6A	1.79e-04	1116	27	6	31753913
Pubmed	Little skate genome provides insights into genetic programs essential for limb-based locomotion.	DNMBP SERINC1	2.01e-04	27	27	2	36288084
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	STUB1 UBR5	2.17e-04	28	27	2	35474067
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KAT6B BRPF1 KAT6A	2.44e-04	157	27	3	30186101
Pubmed	Lem2 is essential for cardiac development by maintaining nuclear integrity.	ARRDC3 LMNA	2.84e-04	32	27	2	37067297
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF131 NOL4 NOL4L UBR5	2.90e-04	418	27	4	34709266
Pubmed	RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.	ZNF131 LMNA	3.60e-04	36	27	2	17573780
Pubmed	Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes.	STUB1 UBR5	4.67e-04	41	27	2	32723828
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	WASHC2C LMNA LEO1 STUB1	5.83e-04	503	27	4	16964243
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	FNBP1L FLG2 LMNA LEO1 STUB1 UBR5	6.36e-04	1415	27	6	28515276
Pubmed	Human transcription factor protein interaction networks.	ZNF131 NOL4 NOL4L FLG2 STUB1 WASHC2A	6.70e-04	1429	27	6	35140242
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DMXL2 KAT6B UBR5	6.97e-04	225	27	3	12168954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CACHD1 KAT6B DNMBP SERINC1	7.03e-04	529	27	4	14621295
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	WASHC2C LEO1 KAT6B UBR5	7.49e-04	538	27	4	28524877
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	LMNA LEO1 STUB1	7.52e-04	231	27	3	16452087
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	CACHD1 UBR5 PDCL3	7.61e-04	232	27	3	25515538
Interaction	KAT6B interactions	KAT6B BRPF1 KAT6A	1.25e-05	34	27	3	int:KAT6B
Interaction	JADE2 interactions	KAT6B BRPF1 KAT6A	3.56e-05	48	27	3	int:JADE2
Interaction	JADE3 interactions	KAT6B BRPF1 KAT6A	4.28e-05	51	27	3	int:JADE3
Cytoband	15q21.2	DMXL2 LEO1	1.34e-04	29	27	2	15q21.2
Cytoband	Ensembl 112 genes in cytogenetic band chr15q21	DMXL2 LEO1	4.87e-03	177	27	2	chr15q21
Cytoband	Ensembl 112 genes in cytogenetic band chr10q11	WASHC2C WASHC2A	5.47e-03	188	27	2	chr10q11
Cytoband	16p13.3	CACNA1H STUB1	9.05e-03	244	27	2	16p13.3
GeneFamily	WASH complex	WASHC2C WASHC2A	1.40e-05	6	18	2	1331
GeneFamily	PHD finger proteins	KAT6B BRPF1 KAT6A	9.22e-05	90	18	3	88
GeneFamily	Zinc fingers C2HC-type\|PHD finger proteins\|Lysine acetyltransferases	KAT6B KAT6A	1.11e-04	16	18	2	66
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT6B KAT6A	1.26e-04	17	18	2	486
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	FAM171A1 FNBP1L KAT6B DNMBP UBR5 KAT6A	6.59e-06	466	27	6	M13522
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	FNBP1L KAT6B UBR5 KAT6A	1.43e-05	145	27	4	M1810
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	FAM171A1 DMXL2 FNBP1L KAT6B DNMBP UBR5 KAT6A	1.94e-05	856	27	7	M4500
Coexpression	GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP	ZNFX1 LMNA SERINC1 PDCL3	5.03e-05	200	27	4	M7022
ToppCell	COPD-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	DMXL2 LMNA DNMBP WASHC2A	5.44e-06	194	27	4	7d682408e9a6239a4e47befc9376e760cc3d133a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ARRDC3 FNBP1L SERINC1	2.65e-05	96	27	3	56e993d37b7958abe56682422536045550e29b41
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D175\|Adult / Lineage, Cell type, age group and donor	FAM171A1 CACHD1 ATL2	1.00e-04	150	27	3	b0b6ba3686d3eb8a9b249d30be14111de3b893be
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	WASHC2C WASHC2A KAT6A	1.19e-04	159	27	3	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh\|GI_large-bowel / Manually curated celltypes from each tissue	CACNA1H ZNFX1 SERINC1	1.28e-04	163	27	3	4104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TYW1 WASHC2A KAT6A	1.30e-04	164	27	3	1aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	LMNA KAT6B KAT6A	1.48e-04	171	27	3	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM171A1 NOL4L CACHD1	1.66e-04	178	27	3	31c847d7f7aa0f6d820afbb45d507992f5e9dc2f
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HRC LMNA PDCL3	1.77e-04	182	27	3	da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCell	COPD-Myeloid-Mast\|World / Disease state, Lineage and Cell class	FAM171A1 CACNA1H LMNA	1.77e-04	182	27	3	68a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCell	Cerebellum-Endothelial-MURAL\|Cerebellum / BrainAtlas - Mouse McCarroll V32	HRC LMNA PDCL3	1.77e-04	182	27	3	b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	NOL4L WASHC2C WASHC2A	1.80e-04	183	27	3	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 NOL4L LMNA	1.86e-04	185	27	3	afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	FAM171A1 CACHD1 FNBP1L	1.86e-04	185	27	3	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 NOL4L LMNA	1.86e-04	185	27	3	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	COPD-Myeloid-Mast\|COPD / Disease state, Lineage and Cell class	FAM171A1 CACNA1H LMNA	1.89e-04	186	27	3	def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 NOL4L LMNA	1.98e-04	189	27	3	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DMXL2 CACNA1H LMNA	1.98e-04	189	27	3	2aebea7a6c2f83112d7c504b742f2c04b92e459a
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DMXL2 NOL4L LMNA	1.98e-04	189	27	3	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HRC CACNA1H LMNA	2.01e-04	190	27	3	a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCell	PBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DMXL2 WASHC2C WASHC2A	2.08e-04	192	27	3	b86476037ddf8904c1d8a6b3763af7242c031cf3
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HRC CACNA1H LMNA	2.08e-04	192	27	3	5995bae840c0b3f420288f557634d0ae9a12a6ae
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HRC CACNA1H LMNA	2.08e-04	192	27	3	dee97f650ae6f4d07a142ade402aae1905791a22
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACHD1 ARRDC3 SERINC1	2.20e-04	196	27	3	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACHD1 ARRDC3 SERINC1	2.20e-04	196	27	3	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	FNBP1L WASHC2C WASHC2A	2.24e-04	197	27	3	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HRC CACNA1H LMNA	2.24e-04	197	27	3	fd65a9b41df618ff2a09d76dcf9f1ca3f3bdf52a
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HRC CACNA1H LMNA	2.27e-04	198	27	3	3222d064b6ecab0caa450a59fc1dc79e26fc6fd5
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-Neuronal-Immature_Interneurons\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	ARRDC3 FNBP1L KAT6B	2.27e-04	198	27	3	5798640425cabf4ac517b7f96a9dfd32f6e5e7c5
ToppCell	COPD-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	DMXL2 ARRDC3 DNMBP	2.31e-04	199	27	3	1cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	NOL4 ARRDC3 FNBP1L	2.31e-04	199	27	3	a255484ba77bd2741a541da278efc8cf4abbe570
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-MAIT\|ICU-SEP / Disease, condition lineage and cell class	FAM171A1 LEO1 KAT6A	2.31e-04	199	27	3	2f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	DMXL2 LMNA DNMBP	2.31e-04	199	27	3	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	NOL4 NOL4L FNBP1L	2.34e-04	200	27	3	1decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	NOL4 ARRDC3 FNBP1L	2.34e-04	200	27	3	e4f0bb57be1112869c7068d0a789c2b802a442dd
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	NOL4 ARRDC3 FNBP1L	2.34e-04	200	27	3	306926cb7a847871641f02e03d52dc56fd55711c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	NOL4 FNBP1L SERINC1	2.34e-04	200	27	3	04699d1149a143b96d6f292c0d70c4d3e6dfc611
Drug	anacardic acid	CACNA1H KAT6B KAT6A	5.91e-06	30	27	3	CID000167551

Protein segments in the cluster

Peptide	Gene	Start	Entry
NDRDERDDDSHEDRG	CACHD1	1146	Q5VU97
EQRHETSDHEAEEPD	DNMBP	336	Q6XZF7
HENDDADREDEEHSQ	DMXL2	421	Q8TDJ6
ADREDEEHSQEDRER	DMXL2	426	Q8TDJ6
HERDDDNSEEGFHTI	ARRDC3	91	Q96B67
NEDHDADDEDDSHME	KAT6B	1421	Q8WYB5
HRHQEEESETEEDEE	FLG2	106	Q5D862
HQRRSAHEEEEDDDD	FAM171A1	851	Q5VUB5
SDDERPQASDEEHRH	LEO1	246	Q8WVC0
EEHRHSDDEEEQDHK	LEO1	256	Q8WVC0
EDDEDEDGDDLLHHH	LMNA	551	P02545
EMDAEDAHHQREAND	GPR179	1046	Q6PRD1
DAHHQREANDVDEDR	GPR179	1051	Q6PRD1
LEDHEDEFNEEDERA	PDCL3	56	Q9H2J4
DDDDDDHDDHEDNDK	NOL4L	161	Q96MY1
NDDHDADDEDDGHLE	KAT6A	1311	Q92794
HGHHNEFDDEFEDDD	FNBP1L	521	Q5T0N5
QRNHEGDEDDSHVRA	STUB1	181	Q9UNE7
AHEDDHNFELDEEAL	ATL2	66	Q8NHH9
RIDSHREDAAELDDD	CACNA1H	1231	O95180
PSHRHQGHEEDDDDD	HRC	236	P23327
RHRSHEEDDNDDDDV	HRC	296	P23327
PDHRHQGHRDEEEDE	HRC	341	P23327
DDHEDHDDSEKVNET	NOL4	386	O94818
EDGDDVHRAVDNERD	SERINC1	366	Q9NRX5
DEATHHTEDAAEEER	BRPF1	756	P55201
EEEESDEDFAHHSDN	WASHC2C	226	Q9Y4E1
GHASDEARDQRHDQE	ZNFX1	86	Q9P2E3
EEEESDEDFAHHSDN	WASHC2A	226	Q641Q2
EAAREDHEDAEDLET	ZNF131	586	P52739
HEQDELHHRDTEEEE	TYW1	276	Q9NV66
EEDHHDEQEEHGEEN	UBR5	1581	O95071