Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscalcium-independent cell-matrix adhesion

FN1 PKD1

2.31e-054412GO:0007161
GeneOntologyCellularComponentGolgi lumen

MUC19 MUC16 MUC12 ACAN

6.72e-05109424GO:0005796
MousePhenopolyhydramnios

ACAN PKD1

1.52e-053322MP:0004020
DomainVWC_out

JAG2 MUC19

7.85e-0419412SM00215
DomainSEA

MUC16 MUC12

1.06e-0322412PF01390
DomainSEA

MUC16 MUC12

1.16e-0323412PS50024
DomainSEA_dom

MUC16 MUC12

1.16e-0323412IPR000082
DomainUBA

VPS13D UBAP2L

1.97e-0330412SM00165
DomainUBA

VPS13D UBAP2L

2.83e-0336412PF00627
DomainVWC

JAG2 MUC19

3.14e-0338412SM00214
DomainVWFC_2

JAG2 MUC19

3.14e-0338412PS50184
DomainVWF_dom

JAG2 MUC19

3.83e-0342412IPR001007
DomainUBA

VPS13D UBAP2L

4.20e-0344412IPR015940
DomainUBA

VPS13D UBAP2L

4.77e-0347412PS50030
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

NFASC HDAC6 MYLK EHMT2 RGL2 WNK2 PKD1

1.29e-0732942717474147
Pubmed

Gain of LINC00624 Enhances Liver Cancer Progression by Disrupting the Histone Deacetylase 6/Tripartite Motif Containing 28/Zinc Finger Protein 354C Corepressor Complex.

HDAC6 UBAP2L TRIM28

1.37e-07942332869873
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CEP170 ARHGAP4 ZNF536 TSG101 SF3B3 HDAC6 EHMT2 TRIM28 ADCY6 ZNF574

6.43e-071116421031753913
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC19 MUC16 MUC12

1.32e-061842318834073
Pubmed

Tolvaptan plus pasireotide shows enhanced efficacy in a PKD1 model.

ADCY6 PKD1

1.42e-06242224994926
Pubmed

Adenylyl cyclase 6 deficiency ameliorates polycystic kidney disease.

ADCY6 PKD1

1.42e-06242224158982
Pubmed

An ESCRT-dependent step in fatty acid transfer from lipid droplets to mitochondria through VPS13D-TSG101 interactions.

VPS13D TSG101

1.42e-06242233623047
Pubmed

Outcome of lumbar epidural steroid injection is predicted by assay of a complex of fibronectin and aggrecan from epidural lavage.

FN1 ACAN

1.42e-06242221224775
Pubmed

Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease.

HDAC6 PKD1

1.42e-06242228887310
Pubmed

Interaction of the leucine-rich repeats of polycystin-1 with extracellular matrix proteins: possible role in cell proliferation.

FN1 PKD1

4.27e-06342211752017
Pubmed

Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier.

NFASC FN1

4.27e-06342222009740
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12

4.27e-06342226770020
Pubmed

HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.

HDAC6 PKD1

4.27e-06342223152903
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CEP170 NAV1 NFASC TSG101 SF3B3 GTPBP1 FN1 UBAP2L TRIM28 WNK2

5.95e-061431421037142655
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

JAG2 CEP170 NAV1 NFASC MBTPS1 BOD1L1 USF3 ZBTB20 UBAP2L WNK2

8.43e-061489421028611215
Pubmed

Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis.

NAV1 ACAN

8.53e-06442238172636
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NAV1 MBTPS1 BOD1L1 ZNF536 UBAP2L ADCY6

9.09e-0640742612693553
Pubmed

Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1.

FN1 ACAN

1.42e-05542216061471
Pubmed

A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.

GTPBP1 TRIM28 ZNF574

2.10e-054442326471122
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC19 MUC16

2.13e-05642219110483
Pubmed

SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response.

EHMT2 TRIM28

2.13e-05642223034801
Pubmed

Adamts5-/- Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate With Ascending Aortic Anomalies.

MYLK ACAN

2.13e-05642231366218
Pubmed

A human MAP kinase interactome.

NAV1 USF3 MUC12 RGL2 TRIM28 WNK2

2.47e-0548642620936779
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

CEP170 NAV1 BOD1L1 TSG101 GTPBP1 UBAP2L

2.83e-0549842636634849
Pubmed

Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.

EHMT2 TRIM28

2.98e-05742224735877
Pubmed

Calcium signaling induces partial EMT and renal fibrosis in a Wnt4mCherry knock-in mouse model.

FN1 ADCY6 PKD1

3.68e-055342338653356
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

CEP170 SF3B3 HDAC6 PPAT UBAP2L TRIM28

4.97e-0555142634728620
Pubmed

Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities.

FN1 ACAN

5.10e-05942215296947
Pubmed

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration.

TSG101 FN1

5.10e-05942226456826
Pubmed

MBTPS1/SKI-1/S1P proprotein convertase is required for ECM signaling and axial elongation during somitogenesis and vertebral development†.

MBTPS1 FN1

5.10e-05942225652402
Pubmed

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.

NAV1 NFASC

5.10e-05942226671463
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CEP170 NADK NAV1 BOD1L1 VPS13D DENND4A RGL2

7.05e-0586142736931259
Pubmed

The etiology of cleft palate formation in BMP7-deficient mice.

JAG2 FN1

7.78e-051142223516636
Pubmed

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development.

FN1 ACAN

7.78e-051142238750698
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

CEP170 NADK DENND4A TRIM28

8.21e-0519042415161933
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

JAG2 MAGEE1 GMEB2 UBAP2L ADCY6 WNK2

8.56e-0560842616713569
Pubmed

TRIM28 functions as a negative regulator of aggresome formation.

HDAC6 TRIM28

9.32e-051242233783327
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CEP170 NAV1 NFASC EHMT2 UBAP2L TRIM28 WNK2

1.41e-0496342728671696
Pubmed

Apical ectodermal ridge morphogenesis in limb development is controlled by Arid3b-mediated regulation of cell movements.

JAG2 FN1

1.48e-041542221307092
Pubmed

Satb2 is required for the regionalization of retrosplenial cortex.

ZBTB20 FN1

1.48e-041542231666685
Pubmed

Disrupting the TRIB3-SQSTM1 interaction reduces liver fibrosis by restoring autophagy and suppressing exosome-mediated HSC activation.

TSG101 FN1

1.48e-041542231286822
Pubmed

Muscleblind-like 1 is required for normal heart valve development in vivo.

FN1 ACAN

1.48e-041542226472242
Pubmed

Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.

FN1 ACAN

1.48e-041542238018454
Pubmed

TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.

HDAC6 TRIM28

1.48e-041542219321449
Pubmed

Patterning and folding of intestinal villi by active mesenchymal dewetting.

MYLK FN1

1.48e-041542238781967
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

MUC19 BOD1L1 VPS13D

1.62e-048742337495603
Pubmed

A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.

SF3B3 TRIM28

1.69e-041642211013263
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

VPS13D SF3B3 TRIM28 WNK2

1.86e-0423542430258100
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CEP170 NADK NAV1 DENND4A HDAC6

1.95e-0444642524255178
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

CEP170 BOD1L1 SF3B3 HDAC6 UBAP2L TRIM28

1.96e-0470842639231216
Pubmed

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.

FN1 ACAN

2.15e-041842235503090
Pubmed

Sox5 and Sox6 are required for notochord extracellular matrix sheath formation, notochord cell survival and development of the nucleus pulposus of intervertebral discs.

FN1 ACAN

2.15e-041842212571105
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

CEP170 SF3B3 GTPBP1 PPAT UBAP2L TRIM28

2.23e-0472542627025967
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ADAMTS12 RC3H2 ZBTB20 MYLK EHMT2 WNK2

2.31e-0473042634857952
Pubmed

The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification.

ADAMTS12 ACAN

2.40e-041942229618652
Pubmed

Site-1 protease is essential for endochondral bone formation in mice.

MBTPS1 ACAN

2.40e-041942218025304
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RC3H2 BOD1L1 EHMT2 UBAP2L TRIM28

2.46e-0446942527634302
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

CEP170 NADK DENND4A SF3B3

2.54e-0425542415324660
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

BOD1L1 TSG101 DENND4A SF3B3 GTPBP1 PPAT UBAP2L TRIM28

2.65e-04142542830948266
Pubmed

BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response.

FN1 ACAN

2.67e-042042229483282
Pubmed

Identification and proteomic profiling of exosomes in human urine.

TSG101 PKD1

2.95e-042142215326289
Pubmed

Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis.

MBTPS1 ACAN

3.24e-042242225147951
Pubmed

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.

FN1 ACAN

3.24e-042242227527664
Pubmed

Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis.

MYLK FN1

3.24e-042242221979435
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

JAG2 NADK NAV1 RGL2 TRIM28 WNK2 PKD1

3.27e-04110542735748872
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

CEP170 SF3B3 GTPBP1 UBAP2L

3.33e-0427442434244482
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

HDAC6 EHMT2 UBAP2L TRIM28 ZNF574

3.39e-0450342516964243
Pubmed

Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.

SF3B3 EHMT2 TRIM28

3.77e-0411642321549307
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

JAG2 FN1 EHMT2

3.97e-0411842321078624
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

CEP170 BOD1L1 SF3B3 FN1 UBAP2L TRIM28

3.99e-0480942632129710
Pubmed

Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1.

TSG101 SF3B3

4.20e-042542212029088
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARHGAP4 NFASC SF3B3 GMEB2 WNK2

4.27e-0452942514621295
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FN1 ACAN

4.54e-042642234189436
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

FN1 ACAN

4.90e-042742235894043
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

NAV1 VPS13D UBAP2L

5.27e-0413042312421765
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

CEP170 NAV1 TRIM28

5.51e-0413242316944949
Pubmed

Isolation and characterization of proteins associated with histone H3 tails in vivo.

EHMT2 TRIM28

6.06e-043042217403666
Pubmed

Heritable Thoracic Aortic Disease Overview

MYLK PKD1

6.06e-043042220301299
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

TSG101 DENND4A ZBTB20 GMEB2 EHMT2 TRIM28

6.11e-0487742620211142
Pubmed

Functional analysis of secreted and transmembrane proteins critical to mouse development.

MBTPS1 FN1

6.47e-043142211431694
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

ZNF536 ZBTB20

6.47e-043142227798109
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

CEP170 SF3B3 UBAP2L TRIM28

6.70e-0433042432529326
Pubmed

Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus.

ZBTB20 FN1

6.90e-043242220308569
Pubmed

MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases.

MAGEE1 TRIM28

6.90e-043242220864041
Pubmed

MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity.

ZNF536 HDAC6 PPAT

7.98e-0415042322678362
Pubmed

The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.

TSG101 HDAC6 GTPBP1 TRIM28

8.35e-0435042426549023
Pubmed

Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate.

JAG2 FN1

8.74e-043642220672350
Pubmed

Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.

CEP170 FN1 UBAP2L

8.94e-0415642329961565
Pubmed

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.

RC3H2 UBAP2L TRIM28

8.94e-0415642326170170
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

CEP170 NADK SEC16B DENND4A

9.36e-0436142426167880
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

CEP170 FN1 EHMT2

9.44e-0415942330581152
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CEP170 NADK NAV1 TSG101 DENND4A SF3B3 ADCY6

9.45e-04132142727173435
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MBTPS1 MUC12 SF3B3 PPAT EHMT2 TRIM28 ZNF574

9.70e-04132742732694731
Pubmed

Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.

FN1 ACAN

9.74e-043842229743679
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

ARHGAP4 FGD3

9.74e-043842211756498
Pubmed

A SMAD1/5-YAP signalling module drives radial glia self-amplification and growth of the developing cerebral cortex.

NAV1 EHMT2

9.74e-043842232541003
Pubmed

Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse.

FN1 ACAN

1.03e-033942221606205
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RC3H2 DENND4A GTPBP1 ADCY6 ZNF574

1.08e-0365042538777146
Pubmed

Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis.

FN1 ACAN

1.08e-034042230578393
Pubmed

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.

ZNF536 FGD3

1.08e-034042227657450
InteractionINPP5E interactions

CEP170 NADK NAV1 DENND4A

9.12e-0665414int:INPP5E
InteractionKIF13B interactions

NADK NAV1 DENND4A SF3B3 TRIM28

9.89e-06142415int:KIF13B
InteractionCBY1 interactions

CEP170 NADK NAV1 TSG101 DENND4A

3.27e-05182415int:CBY1
InteractionKLHL4 interactions

MUC19 BOD1L1 VPS13D

4.09e-0533413int:KLHL4
InteractionCCAR2 interactions

CEP170 RC3H2 SF3B3 HDAC6 FN1 TRIM28

5.74e-05337416int:CCAR2
InteractionEIF5B interactions

RC3H2 BOD1L1 HDAC6 FN1 ZNF574

6.77e-05212415int:EIF5B
InteractionLINC00624 interactions

HDAC6 UBAP2L TRIM28

6.79e-0539413int:LINC00624
InteractionIGF2BP2 interactions

RC3H2 HDAC6 GTPBP1 FN1 UBAP2L TRIM28

7.89e-05357416int:IGF2BP2
InteractionHNRNPAB interactions

RC3H2 BOD1L1 HDAC6 MYLK FN1 TRIM28

9.75e-05371416int:HNRNPAB
InteractionYBX1 interactions

RC3H2 TSG101 SF3B3 HDAC6 FN1 UBAP2L TRIM28 ZNF574

1.16e-04752418int:YBX1
InteractionDCLK1 interactions

CEP170 NADK NAV1 DENND4A

1.27e-04127414int:DCLK1
InteractionMAST3 interactions

NADK NAV1 DENND4A TRIM28

1.35e-04129414int:MAST3
InteractionLASP1 interactions

CEP170 HDAC6 FN1 EHMT2 TRIM28

1.39e-04247415int:LASP1
InteractionANXA10 interactions

TSG101 PKD1

1.44e-049412int:ANXA10
InteractionUPF1 interactions

CEP170 RC3H2 TSG101 HDAC6 FN1 UBAP2L TRIM28

1.53e-04581417int:UPF1
InteractionYWHAG interactions

CEP170 NADK NAV1 RC3H2 BOD1L1 VPS13D DENND4A SF3B3 FN1 RGL2

1.53e-0412484110int:YWHAG
InteractionMYL6 interactions

ADAMTS12 BOD1L1 HDAC6 MYLK FN1

1.61e-04255415int:MYL6
InteractionYWHAE interactions

CEP170 NADK NAV1 RC3H2 DENND4A HDAC6 FN1 RGL2 TRIM28 WNK2

1.62e-0412564110int:YWHAE
InteractionZNF518A interactions

HDAC6 EHMT2 TRIM28

1.80e-0454413int:ZNF518A
InteractionFASN interactions

MBTPS1 TSG101 MUC12 SF3B3 HDAC6 PPAT FN1 TRIM28 ZNF574

2.30e-041062419int:FASN
InteractionKRT8 interactions

NAV1 DENND4A SF3B3 HDAC6 FN1 PKD1

2.49e-04441416int:KRT8
InteractionPABPC4 interactions

RC3H2 TSG101 HDAC6 FN1 UBAP2L TRIM28

2.52e-04442416int:PABPC4
InteractionYWHAH interactions

CEP170 NADK NAV1 BOD1L1 VPS13D DENND4A FN1 RGL2 WNK2

3.03e-041102419int:YWHAH
InteractionZNF10 interactions

HDAC6 TRIM28

3.11e-0413412int:ZNF10
InteractionMRPS23 interactions

RC3H2 HDAC6 FN1 TRIM28 ZNF574

3.21e-04296415int:MRPS23
InteractionPOLR1B interactions

RC3H2 HDAC6 GMEB2 TRIM28

3.23e-04162414int:POLR1B
InteractionFUBP3 interactions

RC3H2 GTPBP1 FN1 UBAP2L TRIM28

3.26e-04297415int:FUBP3
InteractionGSK3A interactions

RC3H2 VPS13D DENND4A SF3B3 HDAC6 TRIM28

3.27e-04464416int:GSK3A
InteractionUBAP2L interactions

RC3H2 GTPBP1 FN1 UBAP2L TRIM28

3.31e-04298415int:UBAP2L
InteractionYWHAQ interactions

CEP170 NADK NAV1 VPS13D DENND4A HDAC6 FN1 RGL2 TRIM28

3.37e-041118419int:YWHAQ
Cytoband3q13.2

USF3 ZBTB20

3.74e-04314223q13.2
CytobandEnsembl 112 genes in cytogenetic band chr3q13

CASR USF3 ZBTB20

1.10e-03221423chr3q13
GeneFamilyCD molecules|Mucins

MUC19 MUC16 MUC12 MUC22

1.98e-0821264648
GeneFamilyFibronectin type III domain containing

NFASC MYLK FN1

1.52e-03160263555
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

ACAN PKD1

1.58e-03412621298
CoexpressionGSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_UP

BOD1L1 ZBTB20 RGL2 ADCY6 PKD1

1.66e-05200425M8514
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

NAV1 ARHGAP4 RC3H2 ZBTB20 MYLK FN1 ADCY6

1.35e-04721427M1999
CoexpressionGARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TAN_DN

NAV1 FN1

1.37e-0411422M27966
CoexpressionNABA_ECM_AFFILIATED

MUC19 MUC16 MUC12 MUC22

1.58e-04170424M5880
CoexpressionGSE40493_BCL6_KO_VS_WT_TREG_UP

CEP170 BOD1L1 VPS13D FGD3

1.84e-04177424M9401
CoexpressionGSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_UP

ARHGAP4 MAGEE1 RGL2 FGD3

2.56e-04193424M6505
CoexpressionGSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN

BOD1L1 VPS13D RGL2 ZNF574

2.88e-04199424M9443
CoexpressionGSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP

ARHGAP4 DENND4A MYLK FGD3

2.93e-04200424M5276
CoexpressionGSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN

NADK GTPBP1 FN1 RGL2

2.93e-04200424M9675
CoexpressionGSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_UP

ARHGAP4 BOD1L1 HDAC6 UBAP2L

2.93e-04200424M6653
CoexpressionGSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN

NADK RC3H2 UBAP2L FGD3

2.93e-04200424M4022
CoexpressionGSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP

TSG101 HDAC6 ADCY6 PKD1

2.93e-04200424M3425
CoexpressionGSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP

RC3H2 ZBTB20 FGD3 PKD1

2.93e-04200424M3614
CoexpressionGSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP

TSG101 ZBTB20 FGD3 PKD1

2.93e-04200424M3612
CoexpressionGSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN

JAG2 MBTPS1 ZBTB20 PKD1

2.93e-04200424M9765
CoexpressionGSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_UP

RC3H2 TSG101 MAGEE1 FN1

2.93e-04200424M3850
CoexpressionKAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN

ZBTB20 RGL2 ADCY6 PKD1

2.93e-04200424M3025
CoexpressionKAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP

ZBTB20 SF3B3 ADCY6 PKD1

2.93e-04200424M3012
CoexpressionVETTER_TARGETS_OF_PRKCA_AND_ETS1_UP

FN1 UBAP2L

2.97e-0416422M14495
CoexpressionZHANG_UTERUS_C3_PROLIFERATIVE_STROMAL1_STROCXCL14_HIGH_CELL

ZBTB20 MYLK FN1

2.99e-0481423MM16609
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

ADAMTS12 NAV1 MYLK FN1

1.71e-051644242ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

NFASC MYLK FN1 ACAN

2.01e-05171424e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK ACAN WNK2

2.11e-05173424901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK ACAN WNK2

2.11e-05173424fc2602b2ce051cd4c33957d7e3d041ff8a529883
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ADAMTS12 NFASC MYLK ACAN

2.26e-051764242015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF536 MYLK FN1 ACAN

2.68e-051844247b5678718719020b52e7c2a7bd9797987defd7ff
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF536 MYLK FN1 ACAN

2.68e-0518442454e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ADAMTS12 ZNF536 MYLK FN1

2.86e-05187424bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

ADAMTS12 NFASC MYLK FN1

2.86e-0518742492d468dde81125d51daf7abd4703741abe1ab91c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK ACAN WNK2

2.92e-05188424b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Interneuron|GW26 / Sample Type, Dataset, Time_group, and Cell type.

ZNF536 ZBTB20 FGD3

3.03e-0564423fefabdf8d72a8f3caf78eb79d759edb475bdb2ad
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 NFASC FN1 ACAN

3.04e-0519042470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ADAMTS12 NFASC MYLK FN1

3.04e-051904243a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

ADAMTS12 NFASC MYLK FN1

3.23e-05193424ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAMTS12 MYLK FN1 ACAN

3.30e-0519442478dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

ADAMTS12 NFASC MYLK FN1

3.30e-0519442403a269f75a481ea54aea8e6444605db8d6df493d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 NFASC MYLK FN1

3.37e-05195424dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

ADAMTS12 NFASC MYLK FN1

3.37e-0519542461c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

ADAMTS12 NFASC MYLK FN1

3.37e-05195424603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 NFASC MYLK FN1

3.37e-0519542449c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellMesenchymal_cells-Fibro/Chondro_p.|Mesenchymal_cells / Lineage and Cell class

CASR FN1 ACAN FGD3

3.37e-05195424b95a631d54c6cf85e48e1e638703206aaaebc073
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTS12 NFASC MYLK FN1

3.37e-05195424aa0add081881d349099d12efca5cdee098038d4e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 NFASC MYLK FN1

3.43e-05196424802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK ACAN WNK2

3.43e-051964241522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK ACAN WNK2

3.43e-051964241c8294014713684b50885e638668f2ce75f357f0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 NFASC MYLK FN1

3.43e-05196424fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellproximal-mesenchymal-Myofibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CASR ZNF536 MUC12 FN1

3.50e-05197424ab21baea931ff134cf5a7ee369c091230988108b
ToppCellproximal-mesenchymal-Myofibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CASR ZNF536 MUC12 FN1

3.50e-0519742415f2f169758a07143fc7d1bdb58d0b4d750a0be4
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NFASC ZNF536 MYLK FN1

3.50e-05197424bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell(3)_Chondrocytes-(30)_Chondro|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ZBTB20 FN1 ACAN WNK2

3.50e-05197424a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCellproximal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CASR ZNF536 MUC12 FN1

3.50e-05197424c59b64674fb4aaa945c1df7e4a9a3605c7cd2b75
ToppCellBronchial_Biopsy-Mesenchymal-Smooth_muscle|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

JAG2 ARHGAP4 NFASC ACAN

3.50e-0519742498f0184a09563a544f0c2d4df22c9db2fbc95019
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

ZBTB20 FN1 ACAN PKD1

3.57e-051984249f9dcf23ffb333105263132d87b90095642294cf
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

ADAMTS12 NFASC MYLK FN1

3.57e-0519842426e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFASC ZBTB20 FN1 ACAN

3.72e-05200424be527df943a8cedc6452ecef3cafc282db34ceb8
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 NFASC MYLK FN1

3.72e-05200424cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

ZNF536 ZBTB20 MYLK FGD3

3.72e-05200424e16bde12326f0cfc4d03f9307cba0e21ea2389cb
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 NFASC MYLK FN1

3.72e-05200424389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 NFASC MYLK FN1

3.72e-05200424e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NFASC ZBTB20 FN1 ACAN

3.72e-05200424c935caef2988f165e96d8f1ef99ae8963ab9377f
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 NFASC MYLK FN1

3.72e-05200424311fab076f2ceb258e3970eb21e39344b894042a
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFASC ZBTB20 FN1 ACAN

3.72e-05200424d254f6634895486f81d7a8b6f006fbc2679eaa5b
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS12 NFASC MYLK FN1

3.72e-0520042434f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

CEP170 NAV1 NFASC WNK2

3.72e-05200424c92e4fc0442404481fcac623d691dae6215b852d
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NFASC ZBTB20 FN1 ACAN

3.72e-052004248e41a484038216f0c2ad258fd46c0e702a4bb8bf
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 NAV1 SEC16B

1.29e-04104423424a58b04c8b5108b70f15d8353c8e4b9db1e730
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 NAV1 SEC16B

1.29e-0410442311d91471b6c4fa6b00a91d9fd4db72ee60d1f801
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Mgp_(Mgp)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADAMTS12 NAV1 SEC16B

1.29e-041044239b05ae514437eb0c8b1b23607ae8cbc371ffa85b
ToppCellGlobus_pallidus|World / BrainAtlas - Mouse McCarroll V32

ZBTB20 RGL2 PKD1

2.27e-0412642344b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 NFASC MUC22

2.84e-0413642327a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 NFASC MUC22

2.84e-0413642388b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAG2 MUC19 NADK

3.30e-04143423d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

JAG2 MUC19 NADK

3.30e-041434238900b92a24289204b9ec7baccc11594fec7694f1
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CASR ADHFE1 MUC12

3.43e-04145423e808502fa52baf1c400f3c9b918a167127e78af9
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

NAV1 NFASC CASR

3.50e-04146423a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NAV1 MUC16 SEC16B

3.72e-04149423a85a051e0d82430160967e72fa04b55f43e84513
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAV1 MUC16 SEC16B

3.79e-041504237a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK ACAN

3.94e-041524230cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK ACAN

3.94e-04152423ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

ADAMTS12 MYLK FN1

4.49e-041594233f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

NFASC MYLK FN1

4.58e-0416042329c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

NFASC MYLK FN1

4.66e-0416142347b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

USF3 UBAP2L PKD1

4.75e-041624232f19539c455d1e5d514725845234c7547020e6ad
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF536 MYLK FN1

4.92e-04164423e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|E18.5-samps / Age Group, Lineage, Cell class and subclass

ADHFE1 MYLK FN1

4.92e-04164423519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCellLV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

NFASC MYLK ACAN

5.01e-04165423f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GMEB2 EHMT2 PKD1

5.09e-0416642313027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GMEB2 EHMT2 PKD1

5.09e-04166423b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CASR ZNF536 FN1

5.46e-04170423b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 FN1 ACAN

5.55e-04171423b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 FN1 ACAN

5.55e-04171423b0373ed8283ee1792b6a490bff93906546978593
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

NFASC ZNF536 MYLK

5.74e-04173423a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS12 FN1 ACAN

5.84e-04174423778e0317c0c63fa4efd74114feb760975b819d92
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC ACAN WNK2

5.94e-04175423d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC ACAN WNK2

5.94e-04175423454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFASC MYLK ACAN

6.04e-0417642390f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

NAV1 MYLK ADCY6

6.14e-0417742333cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS12 MAGEE1 FN1

6.24e-041784239fc5688cf705a74398d24e10e0aab4758612e72b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JAG2 NAV1 FN1

6.24e-041784235f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JAG2 MUC19 ARHGAP4

6.24e-04178423c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

NFASC MYLK ACAN

6.34e-04179423111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS12 MYLK FN1

6.45e-04180423137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS12 MYLK FN1

6.45e-04180423cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellPericytes-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ADAMTS12 NFASC ACAN

6.55e-0418142335c470988a93381eefa300831aabb813fa1b90bd
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

ADAMTS12 MYLK FN1

6.55e-04181423bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS12 MYLK FN1

6.55e-041814239ede19228ba5c0668a9c06c915510b95585216ef
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 ZBTB20 ACAN

6.55e-0418142335bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 ZBTB20 ACAN

6.55e-0418142370eff83dd85691e977972c660731394d2fcf5cdf
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZNF536 MYLK FN1

6.55e-04181423d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 NFASC FN1

6.55e-04181423c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS12 NFASC FN1

6.55e-04181423c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 MYLK FN1

6.66e-04182423728a2152c166551ac229370c0900fe2bc426ea9b
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-5|TCGA-Breast / Sample_Type by Project: Shred V9

ADAMTS12 DPP3 FN1

6.66e-041824239e48d5b634603bc7a8d29290202a311457678328
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SEC16B ACAN WNK2

6.66e-0418242300a148b1e499bf16325491536d187d4dd6b70c06
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

ADAMTS12 NFASC VPS13D

6.76e-04183423273db6a3b00a93ca852498471187b642b5368185
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC MYLK FN1

6.76e-04183423667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAV1 MYLK FN1

6.76e-041834236b5eef96b28911c752a8b6c0975918c4572cec38
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

NFASC MYLK ACAN

6.76e-04183423a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS12 ZNF536 MYLK

6.76e-0418342312daaea821e49bc94a01e2496331e92a80d27339
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 MYLK FN1

6.76e-04183423af8d86f15a549064530d94bd47081daf59d58ecd
DrugCaCl2

NADK CASR MYLK PPAT ADCY6

8.70e-06156415CID000024854
Drug16 beta-hydroxydigitoxigenin

CASR ADHFE1

1.89e-054412CID000011012
Drug0316684-0000 [391209-55-5]; Up 200; 10uM; PC3; HT_HG-U133A

JAG2 NADK VPS13D MYLK UBAP2L

2.43e-051934157057_UP
DrugCephalothin sodium salt [58-71-9]; Down 200; 9.6uM; HL60; HT_HG-U133A

NADK RC3H2 VPS13D SF3B3 UBAP2L

2.55e-051954152517_DN
DrugCinnarizine [298-57-7]; Up 200; 10.8uM; HL60; HG-U133A

NADK VPS13D FN1 ACAN ZNF574

2.68e-051974151558_UP
Drug0173570-0000 [211245-44-2]; Up 200; 1uM; PC3; HT_HG-U133A

DENND4A ZBTB20 MYLK FN1 ADCY6

2.75e-051984157391_UP
DrugHomochlorcyclizine dihydrochloride [1982-36-1]; Down 200; 10.4uM; MCF7; HT_HG-U133A

VPS13D SF3B3 HDAC6 UBAP2L ZNF574

2.75e-051984157417_DN
Diseasecalcium oxalate nephrolithiasis (is_implicated_in)

CASR FN1

1.88e-055412DOID:0080652 (is_implicated_in)
Diseasepolycystic liver disease (implicated_via_orthology)

HDAC6 PKD1

3.94e-057412DOID:0050770 (implicated_via_orthology)
Diseasepolycystic kidney disease (implicated_via_orthology)

HDAC6 PKD1

1.70e-0414412DOID:0080322 (implicated_via_orthology)
DiseaseSjogren's syndrome (is_marker_for)

MUC19 MUC16

5.10e-0424412DOID:12894 (is_marker_for)
Diseaseessential tremor

NFASC ZBTB20 WNK2

8.98e-04136413EFO_0003108
Diseaseaortic stenosis, aortic valve calcification

NAV1 ACAN

1.57e-0342412EFO_0000266, EFO_0005239
Diseaseureteral obstruction (biomarker_via_orthology)

FN1 ADCY6

1.80e-0345412DOID:5199 (biomarker_via_orthology)
Diseaseend stage renal disease (is_marker_for)

CASR FN1

1.88e-0346412DOID:783 (is_marker_for)
Diseasecomplement C4 measurement

MUC22 EHMT2

2.39e-0352412EFO_0004984
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

MYLK PKD1

2.48e-0353412C4707243

Protein segments in the cluster

PeptideGeneStartEntry
GEIDSVTSSGTAPST

CEP170

1321

Q5SW79
VTTTAGGTAEVAPDA

ADCY6

96

O43306
PSTIAVVGATGSGVS

CASR

136

P41180
DTYSVPGVGTVVSGT

GTPBP1

401

O00178
SPASVTVTVGDEGAD

EHMT2

66

Q96KQ7
VSSSDTGPTSEGGLV

ADAMTS12

1106

P58397
VTTPDTAVDGSGVEG

GMEB2

16

Q9UKD1
EGPISSQETSATSGT

DENND4A

1381

Q7Z401
GSTETTGKIVPSTNG

RC3H2

481

Q9HBD1
SSVTGLSETPVGASI

MUC16

2126

Q8WXI7
ATTTDILGTSTEPGT

MUC16

7726

Q8WXI7
TEGSTVLSEVPSGAT

MUC16

8431

Q8WXI7
AESAITIETGSPGAT

MUC16

8491

Q8WXI7
TIETGSPGATSEGTL

MUC16

8496

Q8WXI7
GTSEPSQESELTTVG

MYLK

1411

Q15746
TEGLSTSVQPTAGEG

MAGEE1

301

Q9HCI5
SGTSVASPVVAGAVT

MBTPS1

411

Q14703
TAGSETITPSTAGSE

MUC22

431

E2RYF6
GSETIPASTAGSETT

MUC22

1081

E2RYF6
ETVVTGGSSTGLLVP

JAG2

1071

Q9Y219
VQGDGVIVSTPTGST

NADK

311

O95544
SSGVTVASEPSVGVS

MUC19

2096

Q7Z5P9
SVGVSGTTGPLAEIS

MUC19

2106

Q7Z5P9
SFIESGPSVVGSGTT

MUC19

2276

Q7Z5P9
ESGTTEPSARVAGVT

MUC19

2326

Q7Z5P9
GTSAEVSGRIEPSAT

MUC19

2341

Q7Z5P9
GSEATGPSVIGSETT

MUC19

2376

Q7Z5P9
TGTTEPSTEGSVAAV

MUC19

2516

Q7Z5P9
ETTRPSGGVTVTSGQ

MUC19

2636

Q7Z5P9
SVVKSGTTGPSVIGT

MUC19

2761

Q7Z5P9
AGSVTTGPSVTGVET

MUC19

2981

Q7Z5P9
TTGLSAEATGTIGPS

MUC19

3076

Q7Z5P9
TTGQSAAESVTTGPV

MUC19

3136

Q7Z5P9
ITGISAVVTGTTGPS

MUC19

3496

Q7Z5P9
AVVTGTTGPSAGVTE

MUC19

3501

Q7Z5P9
EVTGTTGPSAEATGL

MUC19

3721

Q7Z5P9
LSAGVTGTTGPSAEE

MUC19

4186

Q7Z5P9
TGATGPSAEVTETTG

MUC19

4201

Q7Z5P9
LSAEVTGTTGPSAEV

MUC19

4226

Q7Z5P9
ESAEVTGTIGSPAGV

MUC19

4246

Q7Z5P9
PLAGVTGTTGISTEV

MUC19

4366

Q7Z5P9
SAGVTGTTGPSAEET

MUC19

4506

Q7Z5P9
SAEETGATGPSAEVT

MUC19

4516

Q7Z5P9
SAEVTGTTGPSAEET

MUC19

4526

Q7Z5P9
SAEETGATGPSAEVT

MUC19

4536

Q7Z5P9
SAEVTGTTGPSAEVT

MUC19

4566

Q7Z5P9
SAEVTGLPGVSAGVT

MUC19

4576

Q7Z5P9
SAEVTGTTGPLAGVT

MUC19

4726

Q7Z5P9
SAGVTGTTGPSAEET

MUC19

4786

Q7Z5P9
SAEETGATGPSAEVT

MUC19

4796

Q7Z5P9
SAEVTGTTGPSAEVT

MUC19

4826

Q7Z5P9
SAEVTGLPGVSAGVT

MUC19

4836

Q7Z5P9
SAEATETTGPSAGVT

MUC19

4906

Q7Z5P9
SSGVTGTIGPSAEET

MUC19

4986

Q7Z5P9
SAGVTESTGLSPGVT

MUC19

5096

Q7Z5P9
SPGVTGTIGSSAVVT

MUC19

5106

Q7Z5P9
SAGVTGTTGPSAEET

MUC19

5126

Q7Z5P9
SAEETGATGPSAEVT

MUC19

5136

Q7Z5P9
GTSVLSVEVTGTTGP

MUC19

5161

Q7Z5P9
SAGVTGTIGPSAEET

MUC19

5376

Q7Z5P9
LAGVTGTTGPSAVVT

MUC19

5406

Q7Z5P9
VEESTTTGPSAGITG

MUC19

5896

Q7Z5P9
TRGEIITDTTEGTSG

MUC19

7316

Q7Z5P9
GVTGTGPTAETTTFL

MUC19

7711

Q7Z5P9
IVSGTTVAPGSSNTE

MUC19

7946

Q7Z5P9
QEGTTVVSSGITGIP

MUC19

8061

Q7Z5P9
EAGEGLVTITPTTGS

DPP3

581

Q9NY33
EPVVTTEGSSGAAGL

FGD3

506

Q5JSP0
SSGLTSTVGSGLPVE

ACAN

901

P16112
SGATSGVPDLVSGTT

ACAN

1806

P16112
PTTVGATGAVSSTDA

NFASC

1041

O94856
VTSTGITEDGEGPAS

BOD1L1

1791

Q8NFC6
VTSDSGSIVVSGLTP

FN1

1131

P02751
ATPDQTTSEETVGGA

HDAC6

946

Q9UBN7
VSGPSVTLTEGLGTV

C1orf127

366

Q8N9H9
ETTAGTVTPTAIGDS

PKD1

2701

P98161
LIAVPTTSGTGSETT

ADHFE1

181

Q8IWW8
STSSSVGTDVTEGPA

NAV1

1271

Q8NEY1
VVSSVLGATSTGEGP

RGL2

301

O15211
AGRSVPTTTAGATEA

ARHGAP4

196

P98171
TTVGPSRDGTISEDT

TSG101

211

Q99816
VTSSNTGVPDISGSV

UBAP2L

971

Q14157
DPGVTVATDTASGTG

ZNF574

51

Q6ZN55
ESAGIVTSDGSSVPT

PPAT

46

Q06203
TSTATVVASSAPGVG

USF3

366

Q68DE3
VEEVTDSGFLGTTPT

SF3B3

491

Q15393
LPGTGSSVAVTEATG

SEC16B

806

Q96JE7
DSGVSSSIGTEPDSV

ZBTB20

376

Q9HC78
STTPGSSNVTEESGV

ZNF536

686

O15090
ASSIEVGVGEPVSSD

WNK2

1831

Q9Y3S1
SGSTSSGLEVVAPEG

TRIM28

596

Q13263
TSTVEGVKTEGGVSG

VPS13D

4166

Q5THJ4
GESTTSRISPGSTEI

MUC12

2771

Q9UKN1